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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Bioavailability of once-daily tacrolimus formulations used in clinical practice in the management of De Novo kidney transplant recipients: the better study.

PMID: 34851532
Journal: CLINICAL TRANSPLANTATION
Year: 2022
Reference: Clin Transplant. 2022 Mar;36(3):e14550. doi: 10.1111/ctr.14550. Epub 2021 Dec 17.
Impact factor:
Publication type: Paper in international publication
Authors: Andres, Amado; Blanco, Gabriel Bernal; Calvo, Natividad; Carbajo, Beatriz Fernandez; Crespo, Marta; Domingo, Hernandez; Fernandez, Ana; Fernandez, Beatriz; Fructuoso, Ana Sanchez; Fuentes, M Carmen Ruiz et al.
DOI: 10.1111/ctr.14550

Haematological disorders following kidney transplantation.

PMID: 33150431
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Feb 25;37(3):409-420. doi: 10.1093/ndt/gfaa219.
Impact factor:
Publication type: Paper in international publication
Authors: Basak, Grzegorz; Batko, Krzysztof; Capasso, Anna; Capasso, Giavambatista; Drozd-Sokolowska, Joanna; Krzanowska, Katarzyna; Kulicki, Pawel; Malyszko, Jacek; Malyszko, Jolanta; Matuszkiewicz-Rowinska, Joanna et al.
DOI: 10.1093/ndt/gfaa219

Podocytopathy in patients with monoclonal gammopathy: three patients and literature review.

PMID: 35211301
Journal: Clinical Kidney Journal
Year: 2022
Reference: Clin Kidney J. 2021 Sep 28;15(3):417-424. doi: 10.1093/ckj/sfab176. eCollection 2022 Mar.
Impact factor:
Publication type: Review in international publication
Authors: Barrios, Clara; Crespo, Marta; Gabaldon, Alejandra; Gimeno, Javier; Lloveras, Belen; Lop, Joan; Marquez, Eva; Naranjo, Dolores; Puche, Adrian; Ramos, Natalia et al.
DOI: 10.1093/ckj/sfab176

Safety and Effectiveness of Isavuconazole Treatment for Fungal Infections in Solid Organ Transplant Recipients (ISASOT Study).

PMID: 35171022
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Feb 23;10(1):e0178421. doi: 10.1128/spectrum.01784-21. Epub 2022 Feb 16.
Impact factor:
Publication type: Paper in international publication
Authors: Berastegui, Cristina; Bravo, Carles; Campany-Herrero, David; Castells, Lluis; Deu, Maria; Gavalda, Joan; Len, Oscar; Los-Arcos, Ibai; Marquez-Algaba, Ester; Martin-Gomez, Maria Teresa et al.
DOI: 10.1128/spectrum.01784-21

Paternal safety of the use of Mycophenolic Acid in kidney transplant recipients. Results of the EMVARON study.

PMID: 33599030
Journal: CLINICAL TRANSPLANTATION
Year: 2021
Reference: Clin Transplant. 2021 May;35(5):e14256. doi: 10.1111/ctr.14256. Epub 2021 Feb 27.
Impact factor:
Publication type: Paper in international publication
Authors: Coca, A; Cruzado-Vega, L; Fernandez-Tagarro, E; Gonzalez-Rinne, A; Jimenez, C; Lopez-Lopez, I; Martin-Moreno, P L; Mazuecos, A; Mir, M; Perez-Mir, M et al.
DOI: 10.1111/ctr.14256

A multicenter blinded preclinical randomized controlled trial on Jak1/2 inhibition in MRL/MpJ-Fas(lpr) mice with proliferative lupus nephritis predicts low effect size.

PMID: 33607177
Journal: KIDNEY INTERNATIONAL
Year: 2021
Reference: Kidney Int. 2021 Jun;99(6):1331-1341. doi: 10.1016/j.kint.2021.01.024. Epub 2021 Feb 16.
Impact factor:
Publication type: Paper in international publication
Authors: Anders, Hans-Joachim; Boor, Peter; Bulow, Roman D; Jacobs-Cacha, Conxita; Lei, Yutian; Ortiz, Alberto; Sanchez-Nino, Maria D; Sehnert, Bettina; Soler, Maria Jose; Voll, Reinhard E et al.
DOI: 10.1016/j.kint.2021.01.024

A roadmap for optimizing chronic kidney disease patient care and patient-oriented research in the Eastern European nephrology community.

PMID: 33570513
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2020 Dec 22;14(1):23-35. doi: 10.1093/ckj/sfaa218. eCollection 2021 Jan.
Impact factor:
Publication type: Review in international publication
Authors: Barbullushi, Myftar; Blankestijn, Peter J; Bruchfeld, Annette; Bumblyte, Inga A; Cozzolino, Mario; Finne, Patrik; Goumenos, Dimitris; Harambat, Jerome; Jager, Kitty J; Massy, Ziad A et al.
DOI: 10.1093/ckj/sfaa218

Optimizing the timing of nephrology referral for patients with diabetic kidney disease.

PMID: 33564400
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2020 Aug 5;14(1):5-8. doi: 10.1093/ckj/sfaa125. eCollection 2021 Jan.
Impact factor:
Publication type: Editorail in international publication
Authors: de Alvaro Moreno, Fernando; Fernandez-Fernandez, Beatriz; Gorriz Teruel, Jose Luis; Martinez-Castelao, Alberto; Navarro-Gonzalez, Juan F; Ortiz, Alberto; Soler, Maria Jose et al.
DOI: 10.1093/ckj/sfaa125

Authors' Reply.

PMID: 32636207
Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Year: 2020
Reference: J Am Soc Nephrol. 2020 Aug;31(8):1918-1919. doi: 10.1681/ASN.2020060799. Epub 2020 Jul 1.
Impact factor: 9.274
Publication type: Letter or abstract
Authors: Batlle, Daniel, Soler, Maria Jose, Welling, Paul A, Swaminathan, Sundararaman et al.
DOI: 10.1681/ASN.2020060799

Exploring Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors for Organ Protection in COVID-19.

PMID: 32605278
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 Jun 28;9(7). pii: jcm9072030. doi: 10.3390/jcm9072030.
Impact factor: 3.303
Publication type: Review in international publication
Authors: Fernandez-Fernandez, Beatriz, D'Marco, Luis, Gorriz, Jose Luis, Jacobs-Cacha, Conxita, Kanbay, Mehmet, Luis-Lima, Sergio, Porrini, Esteban, Sarafidis, Pantelis, Soler, Maria Jose, Ortiz, Alberto et al.
DOI: 10.3390/jcm9072030

Derivation and external validation of the SIMPLICITY Score as a simple immune-based risk score to predict infection in kidney transplant recipients.

PMID: 32540404
Journal: KIDNEY INTERNATIONAL
Year: 2020
Reference: Kidney Int. 2020 Oct;98(4):1031-1043. doi: 10.1016/j.kint.2020.04.054. Epub 2020 Jun 12.
Impact factor: 8.945
Publication type: Paper in international publication
Authors: Andres, Amado, Aguado, Jose Maria, San Juan, Rafael, Lopez-Medrano, Francisco, Munoz-Cepeda, Miguel Angel, Portoles, Jose Maria, Fernandez-Ruiz, Mario, Seron, Daniel, Alonso, Angel, Lora, David et al.
DOI: 10.1016/j.kint.2020.04.054

Case report: tolvaptan-associated creatine kinase elevation in two patients with autosomal dominant polycystic kidney disease (ADPKD).

PMID: 32514744
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2020
Reference: Eur J Clin Pharmacol. 2020 Oct;76(10):1473-1475. doi: 10.1007/s00228-020-02906-z. Epub 2020 Jun 8.
Impact factor: 2.641
Publication type: Letter whit IF
Authors: Agraz-Pamplona, I, Larrosa-Garcia, M, Bury-Macias, R P, Seron-Micas, D, Montoro-Ronsano, J B et al.
DOI: 10.1007/s00228-020-02906-z

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.