About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 38147137 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2023 Reference: J Am Soc Nephrol. 2023 Dec 26. doi: 10.1681/ASN.0000000000000287. Impact factor: Publication type: Paper in international publication Authors: Abbadessa, Giovanni; Adombi, Caroline Melanie; Ali, Nicole; Bestard, Oriol; Brar, Amarpali; Buti, Maria; Campos, Carolina; Colomer-Castell, Sergi; Cortese, Maria Francesca; Cruzado, Josep M et al. DOI: 10.1681/ASN.0000000000000287
PMID: 38152017 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2023 Reference: Am J Transplant. 2023 Nov 29:S1600-6135(23)00723-2. doi: 10.1016/j.ajt.2023.09.021. Impact factor: Publication type: Paper in international publication Authors: Alberici, Federico; Ansari, Mohammed Javeed; Anton, Jordi; Augustine, Joshua; Benken, Scott; Bestard, Oriol; Bhati, Chandra; Bittermann, Violetta; Bou, Rosa; Calvo Penades, Immaculada et al. DOI: 10.1016/j.ajt.2023.09.021
PMID: 38149524 Journal: European Heart Journal-Acute Cardiovascular Care Year: 2023 Reference: Eur Heart J Acute Cardiovasc Care. 2023 Dec 27:zuad120. doi: 10.1093/ehjacc/zuad120. Impact factor: Publication type: Paper in international publication Authors: Barrabes, Jose A; Calvo-Barcelo, Maria; Campuzano-Ruiz, Raquel; Cebrian-Cuenca, Ana M; Garcia de Lucas, M Dolores; Moreno-Perez, Oscar; Orozco-Beltran, Domingo; Soler, Maria Jose; Vidal-Burdeus, Maria et al. DOI: 10.1093/ehjacc/zuad120
PMID: 38156990 Journal: GENETICS IN MEDICINE Year: 2023 Reference: Genet Med. 2023 Dec 27:101030. doi: 10.1016/j.gim.2023.101030. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Abbadessa, Giovanni; Ali, Nicole; Amendola, Laura M; Astiazaran-Symonds, Esteban; Balmana, Judith; Bestard, Oriol; Brar, Amarpali; Cruzado, Josep M; Dudek, Markus; Foulkes, William D et al. DOI: 10.1016/j.gim.2023.101030
PMID: 35425985 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2022 Reference: J Antimicrob Chemother. 2022 Jun 29;77(7):1989-1991. doi: 10.1093/jac/dkac126. Impact factor: Publication type: Paper in international publication Authors: Bailon, Lucia; Curran, Adrian; Else, Laura; Graterol, Fredzzia; Imaz, Arkaitz; Khoo, Saye; Molto, Jose; Paredes, Roger; Perez, Francisco; Ramos, Natalia et al. DOI: 10.1093/jac/dkac126
PMID: 35410878 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2022 Reference: J Am Soc Nephrol. 2022 Jun;33(6):1223-1224. doi: 10.1681/ASN.2022020164. Epub 2022 Apr 11. Impact factor: Publication type: Letter or abstract Authors: Casal Moura, Marta; Fervenza, Fernando C; Sethi, Sanjeev; Soler, Maria Jose; Specks, Ulrich et al. DOI: 10.1681/ASN.2022020164
PMID: 35384924 Journal: TRANSPLANTATION Year: 2022 Reference: Transplantation. 2022 Jul 1;106(7):1430-1439. doi: 10.1097/TP.0000000000004119. Epub 2022 Apr 1. Impact factor: Publication type: Paper in international publication Authors: Aladren, Maria J; Alcalde, Guillermo; Beneyto, Isabel; Cabello, Sheila; Canal, Cristina; Crespo, Marta; Cruzado, Leonidas; De Arriba, Gabriel; Fernandez-Giron, Fernando; Franco, Antonio et al. DOI: 10.1097/TP.0000000000004119
PMID: 35373449 Journal: CTS-Clinical and Translational Science Year: 2022 Reference: Clin Transl Sci. 2022 Jun;15(6):1544-1555. doi: 10.1111/cts.13276. Epub 2022 Apr 19. Impact factor: Publication type: Paper in international publication Authors: Bilbao, Itxarone; Campos-Varela, Isabel; Caralt, Mireia; Castells, Lluis; Charco, Ramon; Dopazo, Cristina; Garcia, Sonia; Gomez-Gavara, Concepcion; Hidalgo, Ernest; Montoro, Bruno et al. DOI: 10.1111/cts.13276
PMID: 33819521 Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY Year: 2021 Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111268. doi: 10.1016/j.mce.2021.111268. Epub 2021 Apr 2. Impact factor: Publication type: Editorail in international publication Authors: Batlle, Daniel; Soler, Maria Jose et al. DOI: 10.1016/j.mce.2021.111268
PMID: 33777371 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 May 4;14(3):884-890. doi: 10.1093/ckj/sfaa027. eCollection 2021 Mar. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Bolufer, Monica; Draibe, Juliana B; Fulladosa, Xavier; Garcia-Carro, Clara; Martinez-Valenzuela, Laura; Soler, Maria Jose; Tango, Ariel; Torras, Joan et al. DOI: 10.1093/ckj/sfaa027
PMID: 33010054 Journal: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Year: 2021 Reference: Br J Clin Pharmacol. 2021 Apr;87(4):2140-2145. doi: 10.1111/bcp.14582. Epub 2020 Nov 3. Impact factor: Publication type: Paper in international publication Authors: Aguilera, Cristina; Agusti, Antonia; Danes, Immaculada; Gracia, Rosa M; Perello, Manel; Perez, Eulalia; Pigrau, Carles; Sueiras, Maria et al. DOI: 10.1111/bcp.14582
PMID: 33756067 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2021 Reference: Am J Transplant. 2021 Jul;21(7):2573-2582. doi: 10.1111/ajt.16579. Epub 2021 Apr 12. Impact factor: Publication type: Paper in international publication Authors: Aladren, Maria Jose; Andres, Amado; Canal, Cristina; Crespo, Marta; Jimenez-Martin, Carlos; Lopez, Veronica; Mazuecos, Auxiliadora; Melilli, Edoardo; Molina, Maria; Moreso, Francesc et al. DOI: 10.1111/ajt.16579
PMID: 32901289 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Dec 4;35(12):2030-2033. doi: 10.1093/ndt/gfaa193. Impact factor: 4.531 Publication type: Editorail in international publication Authors: Blankestijn, Peter J, Bruchfeld, Annette, Cozzolino, Mario, Fliser, Danilo, Fouque, Denis, Gansevoort, Ron, Goumenos, Dimitrios, Massy, Ziad A, Rychlik, Ivan, Soler, Maria Jose et al. DOI: 10.1093/ndt/gfaa193
PMID: 32905289 Journal: Clinical Kidney Journal Year: 2020 Reference: Clin Kidney J. 2019 Aug 1;13(4):607-612. doi: 10.1093/ckj/sfz105. eCollection 2020 Aug. Impact factor: 3.388 Publication type: Paper in international publication Authors: Segarra-Medrano, Alfons, Martin, Marisa, Agraz, Irene, Vilaprinyo, Merce, Chamoun, Betty, Molina, Maria, Colas-Campas, Laura, Garcia-Carrasco, Alicia, Roche, Sarai, Jatem, Elias et al. DOI: 10.1093/ckj/sfz105
PMID: 32777153 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2020 Reference: Am J Transplant. 2020 Nov;20(11):3030-3041. doi: 10.1111/ajt.16246. Epub 2020 Sep 23. Impact factor: 7.338 Publication type: Paper in international publication Authors: Lorenzo, I, Fava, A, Cucchiari, D, Montero, N, Toapanta, N, Centellas, J, Vila-Santandreu, A, Coloma, A, Meneghini, M, Manonelles, A et al. DOI: 10.1111/ajt.16246
PMID: 32707447 Journal: EBioMedicine Year: 2020 Reference: EBioMedicine. 2020 Aug;58:102899. doi: 10.1016/j.ebiom.2020.102899. Epub 2020 Jul 21. Impact factor: 5.736 Publication type: Paper in international publication Authors: Augustine, Titus, Bhandari, Sunil, Baker, Richard, Berglund, David, Carr, Sue, Game, David, Griffin, Sian, Kalra, Philip A, Lewis, Robert, Mark, Patrick B et al. DOI: 10.1016/j.ebiom.2020.102899
PMID: 24463862 Journal: NEFROLOGIA Year: 2014 Reference: Nefrologia. 2014;34(1):46-52. doi: 10.3265/Nefrologia.pre2013.Oct.12256. Impact factor: 1.442 Publication type: Paper in national publication Authors: Agraz, Irene, Segarra, Alfons, Jatem, Elias, Quiles, M Teresa, Arbos, M Antonia, Ostos, Helena, Valtierra, Naiara, Carnicer, Clara, Salcedo, M Teresa et al. DOI: 10.3265/Nefrologia.pre2013.Oct.12256
PMID: 24321303 Journal: TRANSPLANT REV-ORLAN Year: 2014 Reference: Transplant Rev (Orlando). 2014 Jan;28(1):21-5. doi: 10.1016/j.trre.2013.10.006. Epub 2013 Oct 26. Impact factor: 2.66 Publication type: Paper in international publication Authors: Ibernon, Meritxell, Moreso, Francesc, Seron, Daniel et al. DOI: 10.1016/j.trre.2013.10.006
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.
