About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 35160179 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 Jan 29;11(3). pii: jcm11030728. doi: 10.3390/jcm11030728. Impact factor: Publication type: Paper in international publication Authors: Benaiges, David; Crespo, Marta; Duran, Xavier; Galceran, Isabel; Goday, Albert; Oliveras, Anna; Pascual, Julio; Riera, Marta; Soler, Maria Jose; Vazquez, Susana et al. DOI: 10.3390/jcm11030728
PMID: 35137195 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Nov 23;37(12):2474-2486. doi: 10.1093/ndt/gfac029. Impact factor: Publication type: Paper in international publication Authors: Alpay, Harika; Amouzegar, Atefeh; Ariceta, Gema; Atmis, Bahriye; Bacchetta, Justine; Barany, Peter; Baron, Stephanie; Bayrakci, Umut Selda; Belge, Hendrica; Besouw, Martine et al. DOI: 10.1093/ndt/gfac029
PMID: 35124011 Journal: KIDNEY INTERNATIONAL Year: 2022 Reference: Kidney Int. 2022 May;101(5):1027-1038. doi: 10.1016/j.kint.2021.12.029. Epub 2022 Feb 4. Impact factor: Publication type: Paper in international publication Authors: Ardanuy, Carmen; Bestard, Oriol; Cabanas, Nuria Serra; Cachero, Alba; Calatayud, Laura; Couceiro, Carlos; Crespo, Elena; Crespo, Marta; Cruzado, Josep Maria; Donadeu, Laura et al. DOI: 10.1016/j.kint.2021.12.029
PMID: 34554648 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2022 Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5. Impact factor: Publication type: Letter or abstract Authors: Bestard, Oriol; Campins, Magda; Campos-Varela, Isabel; Castells, Lluis; Crespo, Elena; Esperalba, Juliana; Jouve, Thomas; Len, Oscar; Lopez, Manuel; Moreso, Francesc et al. DOI: 10.1111/ajt.16855
PMID: 33526381 Journal: Hipertension y riesgo vascular Year: 2021 Reference: Hipertens Riesgo Vasc. 2021 Jul-Sep;38(3):125-132. doi: 10.1016/j.hipert.2020.12.001. Epub 2021 Jan 30. Impact factor: Publication type: Review in national publication Authors: Jacobs-Cacha, C; Molina-Van den Bosch, M; Seron, D; Soler, M J; Vergara, A et al. DOI: 10.1016/j.hipert.2020.12.001
PMID: 33406589 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Jan 4;10(1). pii: jcm10010141. doi: 10.3390/jcm10010141. Impact factor: Publication type: Paper in international publication Authors: Castella, Eva; Chamoun, Betty; Cidraque, Ignacio; Gabaldon, Alejandra; Guri, Xavier; Moreso, Francesc; Perello, Manel; Salcedo, Maite; Sellares, Joana; Seron, Daniel et al. DOI: 10.3390/jcm10010141
PMID: 33181156 Journal: KIDNEY INTERNATIONAL Year: 2021 Reference: Kidney Int. 2021 Jan;99(1):227-237. doi: 10.1016/j.kint.2020.10.032. Epub 2020 Nov 9. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Bestard, Oriol; Bini, Claudia; Budge, Kelly L; Cantarelli, Chiara; Comai, Giorgia; Cravedi, Paolo; Delsante, Marco; Fiaccadori, Enrico; Flossmann, Oliver et al. DOI: 10.1016/j.kint.2020.10.032
PMID: 32941394 Journal: TRANSPLANTATION Year: 2021 Reference: Transplantation. 2021 Jan 1;105(1):138-150. doi: 10.1097/TP.0000000000003460. Impact factor: Publication type: Paper in international publication Authors: Alonso-Martinez, Carla; Anton, Andres; Berastegui, Cristina; Castells, Lluis; Del-Rio-Gutierrez, Jose-Manuel; Domenech, Laura; Garcia-Garcia, Sonia; Garcia-Ortega, Patricia; Gomez-Ganda, Laura; Gorgas-Torner, Maria-Queralt et al. DOI: 10.1097/TP.0000000000003460
PMID: 32472097 Journal: LABORATORY INVESTIGATION Year: 2020 Reference: Lab Invest. 2020 Sep;100(9):1169-1183. doi: 10.1038/s41374-020-0440-5. Epub 2020 May 29. Impact factor: 4.197 Publication type: Paper in international publication Authors: Roca-Ho, Heleia, Palau, Vanesa, Gimeno, Javier, Pascual, Julio, Soler, Maria Jose, Riera, Marta et al. DOI: 10.1038/s41374-020-0440-5
PMID: 32463180 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2020 Reference: Am J Transplant. 2020 Sep;20(9):2318-2331. doi: 10.1111/ajt.15898. Epub 2020 May 28. Impact factor: 7.338 Publication type: Paper in international publication Authors: Sapir-Pichhadze, Ruth, Duong van Huyen, Jean-Paul, Farris, Alton B, Fogo, Agnes B, Gibson, Ian W, Glotz, Denis, Gueguen, Juliette, Kikic, Zeljko, Kozakowski, Nicolas, Kraus, Edward et al. DOI: 10.1111/ajt.15898
PMID: 32438732 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2020 Reference: Int J Mol Sci. 2020 May 19;21(10). pii: ijms21103587. doi: 10.3390/ijms21103587. Impact factor: 4.556 Publication type: Review in international publication Authors: Giralt-Lopez, Anna, Molina-Van den Bosch, Mireia, Vergara, Ander, Garcia-Carro, Clara, Seron, Daniel, Jacobs-Cacha, Conxita, Soler, Maria Jose et al. DOI: 10.3390/ijms21103587
PMID: 32399663 Journal: PEDIATRIC NEPHROLOGY Year: 2020 Reference: Pediatr Nephrol. 2020 Oct;35(10):1887-1896. doi: 10.1007/s00467-020-04541-3. Epub 2020 May 12. Impact factor: 2.676 Publication type: Paper in international publication Authors: Garg, Puneet, Cara-Fuentes, Gabriel, Venkatareddy, Madhusudan, Verma, Rakesh, Segarra, Alfons, Cleuren, Audrey C, Martinez-Ramos, Alfonso, Johnson, Richard J et al. DOI: 10.1007/s00467-020-04541-3
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.
