About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 38177531 Journal: EMBO Molecular Medicine Year: 2023 Reference: EMBO Mol Med. 2023 Dec 15. doi: 10.1038/s44321-023-00006-w. Impact factor: Publication type: Paper in international publication Authors: Alberici, Federico; Ansari, Mohammed Javeed; Augustine, Joshua; Ballerini, Paola; Benken, Scott; Bestard, Oriol; Bhati, Chandra; Boer, Judith M; Bueno, Clara; Calvo, Gabriel F et al. DOI: 10.1038/s44321-023-00006-w
PMID: 35373130 Journal: Kidney360 Year: 2022 Reference: Kidney360. 2021 Dec 3;3(2):293-306. doi: 10.34067/KID.0006612021. eCollection 2022 Feb 24. Impact factor: Publication type: Paper in international publication Authors: Agraz Pamplona, Irene; Avello, Alejandro; Bestard, Oriol; Bini, Claudia; Bruchfeld, Annette; Budge, Kelly L; Cantarelli, Chiara; Chrysochou, Constantina; Comai, Giorgia; Cravedi, Paolo et al. DOI: 10.34067/KID.0006612021
PMID: 35320154 Journal: TRANSPLANTATION Year: 2022 Reference: Transplantation. 2022 May 1;106(5):1012-1023. doi: 10.1097/TP.0000000000004075. Epub 2022 Apr 26. Impact factor: Publication type: Paper in international publication Authors: Abd ElHafeez, Samar; Abrahams, Alferso C; Abramowicz, Daniel; Adema, Aaltje Y; Adilovic, Harun; Alferes, Daniela G; Alvila, Goncalo; Ambuehl, Patrice Max; Arias-Cabrales, Carlos; Arnol, Miha et al. DOI: 10.1097/TP.0000000000004075
PMID: 35265335 Journal: Clinical Kidney Journal Year: 2022 Reference: Clin Kidney J. 2021 Jul 10;15(1):5-13. doi: 10.1093/ckj/sfab131. eCollection 2022 Jan. Impact factor: Publication type: Review in international publication Authors: Cruzado, Josep Maria; Montero, Nuria; Oliveras, Laia; Soler, Maria Jose et al. DOI: 10.1093/ckj/sfab131
PMID: 35268550 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 Mar 7;11(5). pii: jcm11051459. doi: 10.3390/jcm11051459. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Bermejo, Sheila; Bestard, Oriol; Bolufer, Monica; Gabaldon, Maria-Alejandra; Garcia-Carro, Clara; Leon, Juan Carlos; Mast, Richard; Seron, Daniel; Soler, Maria Jose et al. DOI: 10.3390/jcm11051459
PMID: 33166580 Journal: KIDNEY INTERNATIONAL Year: 2021 Reference: Kidney Int. 2021 Apr;99(4):986-998. doi: 10.1016/j.kint.2020.10.014. Epub 2020 Nov 7. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Avila, Ana; Bonet, Jose; Cabello, Virginia; Cao, Mercedes; Caravaca-Fontan, Fernando; Diez, Montserrat; Diezhandino, Marian Goicoechea; Egido, Jesus; Espinosa, Mario et al. DOI: 10.1016/j.kint.2020.10.014
PMID: 33623672 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 Aug 11;14(2):482-491. doi: 10.1093/ckj/sfaa110. eCollection 2021 Feb. Impact factor: Publication type: Review in international publication Authors: Agraz, Irene; Ariceta, Gema; Garcia-Carro, Clara; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Moreso, Francesc; Seron, Daniel; Soler, Maria Jose; Toapanta-Gaibor, Nestor; Vergara, Ander et al. DOI: 10.1093/ckj/sfaa110
PMID: 33623683 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 Jan 25;14(2):586-592. doi: 10.1093/ckj/sfz178. eCollection 2021 Feb. Impact factor: Publication type: Paper in international publication Authors: Bada-Bosch, Teresa; Carbayo, Javier; Cases Corona, Clara Maria; Fernandez Lorente, Loreto; Goicoechea, Marian; Huerta, Ana; Malek-Marin, Tamara Gelen; Martinez Valenzuela, Laura; Perez de Jose, Ana; Pocurull, Anna et al. DOI: 10.1093/ckj/sfz178
PMID: 33617203 Journal: TRANSPLANTATION Year: 2021 Reference: Transplantation. 2021 Mar 1;105(3):648-659. doi: 10.1097/TP.0000000000003274. Impact factor: Publication type: Paper in international publication Authors: Astor, Brad C; Chong, Edward; Crespo, Marta; Djamali, Arjang; Gache, Larry; Irish, William; Moreso, Francesc; Nickerson, Peter; Seron, Daniel; Wiebe, Chris et al. DOI: 10.1097/TP.0000000000003274
PMID: 32699615 Journal: Clinical Kidney Journal Year: 2020 Reference: Clin Kidney J. 2020 Jul 16;13(3):297-306. doi: 10.1093/ckj/sfaa104. eCollection 2020 Jun. Impact factor: 3.388 Publication type: Review in international publication Authors: D'Marco, Luis, Puchades, Maria Jesus, Romero-Parra, Maria, Gimenez-Civera, Elena, Soler, Maria Jose, Ortiz, Alberto, Gorriz, Jose Luis et al. DOI: 10.1093/ckj/sfaa104
PMID: 32699618 Journal: Clinical Kidney Journal Year: 2020 Reference: Clin Kidney J. 2020 Jan 3;13(3):380-388. doi: 10.1093/ckj/sfz177. eCollection 2020 Jun. Impact factor: 3.388 Publication type: Paper in international publication Authors: Lopez, Diana, Martin-Gomez, Adoracion, Garcia-Osuna, Rosa, Linares, Tania, Diaz, Montserrat, Martin, Nadia, Barros, Xoana, Marco, Helena, Navarro, Maruja Isabel, Esparza, Noemi et al. DOI: 10.1093/ckj/sfz177
PMID: 32669323 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2020 Reference: J Am Soc Nephrol. 2020 Sep;31(9):1941-1943. doi: 10.1681/ASN.2020050667. Epub 2020 Jul 15. Impact factor: 9.274 Publication type: Letter whit IF Authors: Wysocki, Jan, Lores, Enrique, Ye, Minghao, Soler, Maria Jose, Batlle, Daniel et al. DOI: 10.1681/ASN.2020050667
PMID: 32660793 Journal: NEFROLOGIA Year: 2020 Reference: Nefrologia. 2020 Nov - Dec;40(6):634-639. doi: 10.1016/j.nefro.2020.04.018. Epub 2020 Jul 11. Impact factor: 1.544 Publication type: Paper in national publication Authors: Soler, Maria Jose, Seron, Daniel, Segarra, Alfons, Perez Lafuente, Mercedes, Bolufer, Monica, Garcia-Carro, Clara, Agraz, Irene, Diez Miranda, Iratxe, Jaramillo, Juliana, Arredondo, Karla et al. DOI: 10.1016/j.nefro.2020.04.018
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.