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Neurodegenerative Diseases

The research conducted in our group is geared toward elucidating the cause and molecular mechanisms of neurodegeneration in Parkinson's disease (PD), a disabling, currently incurable common neurodegenerative disorder. To this end, we perform clinical and pre-clinical translational research in both PD patients and in human-relevant experimental in vitro and in vivo PD-related models. 

Elucidating the molecular mechanisms underlying neurodegeneration in PD should allow to: 

  • Identify biomarkers for PD diagnosis, early detection, patient stratification, disease progression, prognosis or response to treatment. This is the objective of the VHIP Project that the team is carrying out.
  • Identify new molecular targets for potential therapeutic intervention and prevention.
  • Develop novel therapeutic strategies with disease-modifying potential.
  • Unravel molecular pathways common to other neurodegenerative diseases and, in a broader sense, brain aging.
     
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News

Vall d'Hebron has participated in a phase III clinical trial which confirmed the efficacy and safety of subcutaneous infusion of levodopa therapy.

This initiative is part of a pioneering study that seeks to assess how the relationship between different age groups can influence the quality of life and mental health of patients.

Dr. Miquel Vila, head of the Neurodegenerative Diseases research group at VHIR, is the co-chair of the local organising committee. And Dr. Ariadna Laguna, principal investigator of the same group, is a scientific ambassador.

Job offers

Study Coordinator - Neurodegenerative diseases group.
Start date:
09/02/2022
End date:
28/02/2022
Document: Download
Research Technician Neurodegenerative Diseases Research Group
Start date:
20/01/2022
End date:
04/02/2022
Document: Download
Postdoctoral Researcher.
Start date:
12/01/2022
End date:
23/02/2022

Coneix i participa al projecte VHIP

Vall d'Hebron Iniciativa per al Parkinson (VHIP) is a research project aimed at the development of biochemical markers for the early detection of Parkinson's disease. This study is carried out in people at high risk of having this disease, because they carry genetic mutations that predispose to the development of Parkinson's or because they present non-motor symptoms that manifest themselves years before motor symptoms.

Access the project and study