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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Team

Clàudia Codina Clavaguera

Clàudia Codina Clavaguera

Predoctoral researcher
Systemic Diseases
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Cristina Nolla Fontana

Cristina Nolla Fontana

Predoctoral researcher
Systemic Diseases
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Esteve Valverde, Enrique

Esteve Valverde, Enrique

Postdoctoral researcher
Systemic Diseases
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Júlia Vivancos Pons

Júlia Vivancos Pons

Research assistant
Systemic Diseases
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Maria Roca Herrera

Maria Roca Herrera

Predoctoral researcher
Systemic Diseases
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Pereira González, Mario Javier

Pereira González, Mario Javier

Predoctoral researcher
Systemic Diseases
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Clàudia Codina Clavaguera

Clàudia Codina Clavaguera

Predoctoral researcher
Systemic Diseases
Read more
Cristina Nolla Fontana

Cristina Nolla Fontana

Predoctoral researcher
Systemic Diseases
Read more
Esteve Valverde, Enrique

Esteve Valverde, Enrique

Postdoctoral researcher
Systemic Diseases
Read more
Júlia Vivancos Pons

Júlia Vivancos Pons

Research assistant
Systemic Diseases
Read more
Maria Roca Herrera

Maria Roca Herrera

Predoctoral researcher
Systemic Diseases
Read more
Pereira González, Mario Javier

Pereira González, Mario Javier

Predoctoral researcher
Systemic Diseases
Read more

Research lines

Spanish Registry of patients with Behçet disease (REGEB).

This is a multicentre study supported by the Systemic Autoimmune Diseases Group from the Spanish Internal Medicine Society. The aim of the study is to describe the different clinical forms of disease presentation in our country and the response of the disease to conventional treatment.

IP: Roser Solans Laque

Spanish Registry of patients with primary Sjögren’s syndrome.

This is a multicentre study supported by the Systemic Autoimmune Diseases Group (GEAS) from the Spanish Internal Medicine Society (SEMI). Its main goal consist in investigate the factors involved in extraglandular development in our country. This study is coordinated by Dr. Manel Ramos  from the Clinic Hospital, Barcelona.

IP: Roser Solans Laque

Cardiac involvement in Churg-Strauss Granulomatosis (EGPE).

Cardiac involvement is one of the most important causes of dead in EGPE. The aim of this study is to investigate the prevalence of silent cardiac involvement in patients with EGPE, and if some chemotaxins (eotaxins 1, 2 and 3) may play a key role in its development, in order to establish an early tretament.

IP: Roser Solans Laque

Genetic bases of giant cell arteritis (GCA).

With this study we aim to investigate the genetic background of the disease, to deepen in its pathogenesis and to be able to establish links between genetic variations and different clinic and biologic patterns. This research is based on a multicentric study and it is led by Prof. Javier Martín from the "Instituto López-Neyra" of Parasitology, CSIC (Granada). We contribute by sending samples from our cohort of patients along with the clinical data, and reviewing the results.

IP: Roser Solans Laque

Blog

News

A Vall d’Hebron team demonstrates, for the first time, the potential of optical genome mapping to detect genetic alterations associated with this rare disease that are not identified using conventional methods.

The study describes the first documented case worldwide of hereditary angioedema transmission through assisted reproduction.

15 researchers from the Rheumatology, Systemic Diseases and the Physiology and Pathophysiology of the Digestive Tract groups gave around 25 presentations.