About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
The presence of the recently discovered retrovirus XMRV ("xenotropic murine leukaemia virus-related virus") is being currently studied in our lab in patients with SLE. This virus has been detected in blood samples of patients suffering from chronic fatigue syndrome (CFS). Interestingly, many patients with lupus also suffer from CFS. Based on these facts, with this project we establish as a hypothesis the possibility of finding XMRV DNA and RNA sequences in peripheral blood mononuclear cells from SLE patients, especially in those with CFS. We are nowadays setting up the already described XMRV-specific PCR and RT-PCR assays. We will also study the immunologic response of these patients against particular XMRV proteins.
IP: -
We are currently enrolled in this multicentre study supported by the “EULAR Sjögren’s Task Force” to elaborate and agree on a systemic disease activity index for patients with primary Sjögren’s syndrome, that will be useful in the management of the disease. This study is coordinated by Dr. Raphaele Seror from the “Service de Rheumatologie Hôpital Bicêtre”, France.
IP: Roser Solans Laque
The so-called obstetric antiphospholipid syndrome seems to have pathogenic, biologic, therapeutic, and evolution features somehow different from the ones observed in those patients who suffer from "classic" antiphospholipid syndrome. Although experience and scientific evidence seem to support this idea, there is a lack of information that allows us to suggest changes in the classification and/or therapeutic criteria. The European Forum on Antiphospholipid Antibody Syndrome has decided to carry on this project and it has chosen the Vall d'Hebron Hospital as the European Coordinating Centre. Many important Spanish and European hospitals will participate in this multicentric study.
IP: Jaume Alijotas Reig
DNA is hypomethylated in T cells from SLE patients. It may lead to an increase in the expression of some genes that are usually silenced and, consequently, autoimmune phenomena may develop. On the other hand, this "unprotected" DNA could be the responsible for triggering anti-DNA antibodies. To find out the reason why this DNA hypomethylation is taking place, we have evaluated the expression level of different DNA methylases and demethylases. We have observed that two demethylases (MBD2 and MBD4) are overexpressed in T CD4+ lymphocytes of patients with SLE. We are now studying the effect the overexpression of these proteins may have in the expression regulation of different molecules involved in the immunologic response.
IP: Alfredo Guillen Del Castillo Collaborators: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Maria Roca Herrera, Janire Perurena Prieto, Irene Sansano Valero Funding agency: Instituto de Salud Carlos III Funding: 75020 Reference: PI22/01804 Duration: 01/01/2023 - 31/12/2025
IP: Sara Marsal Barril Collaborators: Alejandro Gòmez Gomez, Miriam Izquierdo Sans, Judit Álvarez González Funding agency: Fundación Española de Reumatología Funding: 135000 Reference: FER/RECERCA/2021/MARSAL Duration: 14/02/2022 - 13/02/2025
IP: Sara Marsal Barril Collaborators: Antonio Julia Cano, Javier Hoyo Pérez, Elena Granell Pallares, Adria Aterido Ballonga, Montse Sender Beleta Funding agency: EUROPEAN COMMISSION Funding: 1079085 Reference: DOCTIS_H2020_SC1-BHC2019 Duration: 01/01/2020 - 31/12/2025
IP: Sara Marsal Barril Collaborators: Nuria Palau Balaña, Luis Riera Soler, Estefania Moreno Ruzafa, Mireia Lopez Corbeto, Adria Aterido Ballonga Funding agency: Instituto de Salud Carlos III Funding: 208120 Reference: PI19/00225 Duration: 01/01/2020 - 30/06/2024
PMID: 37260447 Journal: Frontiers in Endocrinology Year: 2023 Reference: Front Endocrinol (Lausanne). 2023 May 16;14:1167087. doi: 10.3389/fendo.2023.1167087. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Abumayyaleh, Mohammad; Akin, Ibrahim; Alfonso-Rodriguez, Emilio; Becerra-Munoz, Victor Manuel; Castro Mejia, Alex Fernando; Chipayo, David; El-Battrawy, Ibrahim; Feltes, Gisela; Fernandez-Ortiz, Antonio; Gonzalez, Adelina et al. DOI: 10.3389/fendo.2023.1167087
PMID: 37325877 Journal: ULTRASOUND IN OBSTETRICS & GYNECOLOGY Year: 2023 Reference: Ultrasound Obstet Gynecol. 2023 Jun 16. doi: 10.1002/uog.26290. Impact factor: Publication type: Paper in international publication Authors: Armengol-Alsina, M; Boada, D; Bonacina, E; Comas, M; De Diego, R; Figueras, F; Galindo, A; Gomez Roig, M D; Gonzalez, A; Herraiz, I et al. DOI: 10.1002/uog.26290
PMID: 37597162 Journal: ALLERGY Year: 2023 Reference: Allergy. 2023 Aug 19. doi: 10.1111/all.15854. Impact factor: Publication type: Paper in international publication Authors: Baron, Jens; Brehler, Randolf; Ferrer, Marta; Gimenez-Arnau, Ana Maria; Groffik, Adriane; Grundmann, Sonja; Jakob, Thilo; Labrador-Horrillo, Moises; Maurer, Marcus; Metz, Martin et al. DOI: 10.1111/all.15854
PMID: 37653444 Journal: Orphanet Journal of Rare Diseases Year: 2023 Reference: Orphanet J Rare Dis. 2023 Aug 31;18(1):256. doi: 10.1186/s13023-023-02887-z. Impact factor: Publication type: Paper in international publication Authors: Barba-Romero, Miguel Angel; de la Pena, Jose Luis Patier; de Los Santos Moreno, Alberto; de Los Santos Moreno, Alberto; de Pedro, Ivan Perez; de Ureta, Pablo Tutor; Garate, Igor Gomez; Garcia, Andres Gonzalez; Gil, Roi Suarez; Gomez-Belda, Ana et al. DOI: 10.1186/s13023-023-02887-z
PMID: 33349612 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2022 Reference: J Investig Allergol Clin Immunol. 2022 Jun 20;32(3):191-199. doi: 10.18176/jiaci.0661. Epub 2020 Dec 22. Impact factor: 3.488 Publication type: Paper in international publication Authors: Pedraz, J; Serra-Baldrich, E; Tejedor-Alonso, M A; Velasco, M; Terradas, P; Labrador, M; Munoz-Bellido, F J; Figueras, I; Borbujo, J; Jauregui, I et al. DOI: 10.18176/jiaci.0661
PMID: 35755602 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin. 2022 Jun 10;158(11):509-518. doi: 10.1016/j.medcle.2021.06.023. Epub 2022 Jun 18. Impact factor: 1.725 Publication type: Paper in international publication Authors: Sellares-Nadal, Julia; Almirante, Benito; Guillen-Del-Castillo, Alfredo; Sampol, Julia; Augustin, Salvador; Bosch-Nicolau, Pau; Monforte-Pallares, Arnau; Sempere-Gonzalez, Abiu; Eremiev-Eremiev, Simeon; Miarons, Marta et al. DOI: 10.1016/j.medcle.2021.06.023
PMID: 34932829 Journal: ALLERGY Year: 2022 Reference: Allergy. 2022 Jul;77(7):2147-2162. doi: 10.1111/all.15199. Epub 2022 Jan 15. Impact factor: 13.146 Publication type: Paper in international publication Authors: Valero, Antonio; Toppila-Salmi, Sanna; Tomazic, Peter Valentin; Todo-Bom, Ana; Stellato, Cristiana; Sheikh, Aziz; Sousa-Pinto, Bernardo; Jutel, Marek; De Feo, Giulia; Gerth van Wijk, Roy et al. DOI: 10.1111/all.15199
PMID: 35780057 Journal: Journal of healthcare quality research Year: 2022 Reference: J Healthc Qual Res. 2022 Mar 10. pii: S2603-6479(22)00012-4. doi: 10.1016/j.jhqr.2022.02.006. Impact factor: 0 Publication type: Paper in international publication Authors: Rodriguez, I; Barba, M-A; Cebrian, R; Abadias, M-J; Aller, M-B; Cossio-Gil, Y; Roman, A; Dominguez, J-M; Campins, M; Martinez, J et al. DOI: 10.1016/j.jhqr.2022.02.006
PMID: 34965883 Journal: Allergy Asthma and Clinical Immunology Year: 2021 Reference: Allergy Asthma Clin Immunol. 2021 Dec 29;17(1):137. doi: 10.1186/s13223-021-00641-3. Impact factor: 3.406 Publication type: Paper in international publication Authors: Guilarte, Mar, Sala-Cunill, Anna, Baeza, Maria Luisa, Cabanas, Rosario, Hernandez, Maria Dolores, Ibanez, Ethel, de Larramendi, Carlos Hernando, Lleonart, Ramon, Lobera, Teofilo, Marques, Luis et al. DOI: 10.1186/s13223-021-00641-3
PMID: 34943483 Journal: Diagnostics Year: 2021 Reference: Diagnostics (Basel). 2021 Nov 30;11(12). pii: diagnostics11122246. doi: 10.3390/diagnostics11122246. Impact factor: 3.706 Publication type: Paper in international publication Authors: Mahler, Michael, Malyavantham, Kishore, Seaman, Andrea, Bentow, Chelsea, Anunciacion-Llunell, Ariadna, Sanz-Martinez, Maria Teresa, Vinas-Gimenez, Laura, Selva-O'Callaghan, Albert et al. DOI: 10.3390/diagnostics11122246
PMID: 34944673 Journal: Biomedicines Year: 2021 Reference: Biomedicines. 2021 Dec 7;9(12). pii: biomedicines9121857. doi: 10.3390/biomedicines9121857. Impact factor: 6.081 Publication type: Paper in international publication Authors: Domingo, Sandra, Sole, Cristina, Moline, Teresa, Ferrer, Berta, Cortes-Hernandez, Josefina et al. DOI: 10.3390/biomedicines9121857
PMID: 34936544 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2021 Reference: Clin Exp Rheumatol. 2021 Dec 16. pii: 17754. Impact factor: 4.473 Publication type: Paper in international publication Authors: Gracia Tello, Borja, Ramos Ibanez, Eduardo, Fanlo Mateo, Patricia, Saez Comet, Luis, Martinez Robles, Elena, Rios Blanco, Juan Jose, Mari Alfonso, Begona, Espinosa Garriga, Gerard, Todoli Parra, Jose, Ortego Centeno, Norberto et al. DOI:
PMID: 31594659 Journal: MEDICINA CLINICA Year: 2020 Reference: Med Clin (Barc). 2020 Dec 11;155(11):509-510. doi: 10.1016/j.medcli.2019.07.012. Epub 2019 Oct 5. Impact factor: 1.635 Publication type: Letter whit IF Authors: Gracia-Tello, Borja, Antonio Todoli Parra, Jose, Freire-Dapena, Mayka, Espinosa-Garriga, Gerard, Mari Alfonso, Begona, Garcia-Hernandez, Francisco, Guillen Del Castillo, Alfredo, Ortego Centeno, Norberto, Jose Rios Blanco, Juan, Selva-O'Callaghan, Albert et al. DOI: 10.1016/j.medcli.2019.07.012
PMID: 31694752 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2020 Reference: Clin Exp Rheumatol. 2020 Jul-Aug;38(4):662-669. Epub 2019 Oct 30. Impact factor: 3.319 Publication type: Paper in international publication Authors: Pagan Garcia, Encarnacion, Zegarra-Mondragon, Sixto, Lopez-Gonzalez, Ruth, Martin-Martinez, Maria Auxiliadora, Garcia-Gomez, Carmen, Sanchez-Alonso, Fernando, Gonzalez-Juanatey, Carlos, Manrique Arija, Sara, Bonilla Hernan, Gema, Martinez Pardo, Silvia et al. DOI:
PMID: 32306414 Journal: ALLERGY Year: 2020 Reference: Allergy. 2020 Sep;75(9):2161-2169. doi: 10.1111/all.14329. Impact factor: 8.706 Publication type: Paper in international publication Authors: Vieths, Stefan, Klimek, Ludger, Hoffmann, Hans J, Kalpaklioglu, Ayse F, Demoly, Pascal, Agache, Ioana, Popov, Todor A, Muraro, Antonella, Schmid-Grendelmeier, Peter, Bonini, Sergio et al. DOI: 10.1111/all.14329
PMID: 33110492 Journal: Clinical and Translational Allergy Year: 2020 Reference: Clin Transl Allergy. 2020 Oct 26;10:44. doi: 10.1186/s13601-020-00351-w. eCollection 2020. Impact factor: 5.129 Publication type: Letter or abstract Authors: Bonini, Matteo, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas-Linnemann, Desiree, Mullol, Joaquim, Papadopoulos, Nikos G, Pfaar, Oliver et al. DOI: 10.1186/s13601-020-00351-w
PMID: 31754890 Journal: Current Rheumatology Reports Year: 2019 Reference: Curr Rheumatol Rep. 2019 Nov 21;21(11):64. doi: 10.1007/s11926-019-0864-3. Impact factor: 3.645 Publication type: Review in international publication Authors: Selva-O'Callaghan, Albert, Gil-Vila, Albert, Simo-Perdigo, Marc, Trallero-Araguas, Ernesto, Alvarado-Cardenas, Marcelo, Pinal-Fernandez, Iago et al. DOI: 10.1007/s11926-019-0864-3
PMID: 31752231 Journal: Journal of Clinical Medicine Year: 2019 Reference: J Clin Med. 2019 Nov 18;8(11). pii: jcm8112013. doi: 10.3390/jcm8112013. Impact factor: 5.688 Publication type: Paper in international publication Authors: Villa Blanco, Ignacio, Cavagna, Lorenzo, Trallero-Araguas, Ernesto, Meloni, Federica, Cavazzana, Ilaria, Rojas-Serrano, Jorge, Feist, Eugen, Zanframundo, Giovanni, Morandi, Valentina, Meyer, Alain et al. DOI: 10.3390/jcm8112013
PMID: 30953541 Journal: ARTHRITIS RESEARCH & THERAPY Year: 2019 Reference: Arthritis Res Ther. 2019 Apr 5;21(1):88. doi: 10.1186/s13075-019-1873-3. Impact factor: 4.148 Publication type: Paper in international publication Authors: Reyner, Patricia, Sala, Miquel, Sellas, Agusti, Pitarch, Concepcio, Reina, Delia, Blanco, Jordi, Centelles, Montse, Figuls, Ramon, Gelman, Mario, Arasa, Xavier et al. DOI: 10.1186/s13075-019-1873-3
PMID: 30951790 Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Year: 2019 Reference: J Allergy Clin Immunol. 2019 Jul;144(1):135-143.e6. doi: 10.1016/j.jaci.2019.01.053. Epub 2019 Apr 3. Impact factor: 14.11 Publication type: Paper in international publication Authors: Bindslev-Jensen, Carsten, Bedard, Annabelle, Basagana, Xavier, Anto, Josep M, Garcia-Aymerich, Judith, Devillier, Philippe, Arnavielhe, Sylvie, Bedbrook, Anna, Onorato, Gabrielle L, Czarlewski, Wienczyslawa et al. DOI: 10.1016/j.jaci.2019.01.053
PMID: 28408277 Journal: JOINT BONE SPINE Year: 2018 Reference: Joint Bone Spine. 2018 Jan;85(1):79-84. doi: 10.1016/j.jbspin.2017.03.012. Epub 2017 Apr 11. Impact factor: 3.329 Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu, Berastegui, Cristina, Pinal-Fernandez, Iago, Silveira, Maria Guadalupe, Lopez-Meseguer, Manuel, Monforte, Victor, Castillo, Alfredo Guillen-Del, Simeon-Aznar, Carmen Pilar, Fonollosa-Pla, Vicent, Sole, Joan et al. DOI: 10.1016/j.jbspin.2017.03.012
PMID: 28284772 Journal: Reumatologia clinica Year: 2018 Reference: Reumatol Clin. 2018 May - Jun;14(3):155-159. doi: 10.1016/j.reuma.2016.12.003. Epub 2017 Mar 9. Impact factor: 0 Publication type: Paper in national publication Authors: Zarco, Pedro, Loza, Estibaliz, Sanz, Jesus, Almodovar, Raquel, Torre Alonso, Juan C, Batlle, Enrique, Castillo, Concepcion, Collantes-Estevez, Eduardo, de Miguel, Eugenio, Gonzalez, Senen et al. DOI: 10.1016/j.reuma.2016.12.003
PMID: 30586461 Journal: PLoS One Year: 2018 Reference: PLoS One. 2018 Dec 26;13(12):e0209343. doi: 10.1371/journal.pone.0209343. eCollection 2018. Impact factor: 2.766 Publication type: Paper in international publication Authors: Gonzalez-Serna, David, Carmona, Elio G, Ortego-Centeno, Norberto, Simeon, Carmen P, Solans, Roser, Hernandez-Rodriguez, Jose, Tolosa, Carlos, Castaneda, Santos, Narvaez, Javier, Martinez-Valle, Ferran et al. DOI: 10.1371/journal.pone.0209343
PMID: 30567570 Journal: ARTHRITIS RESEARCH & THERAPY Year: 2018 Reference: Arthritis Res Ther. 2018 Dec 19;20(1):281. doi: 10.1186/s13075-018-1775-9. Impact factor: 4.269 Publication type: Paper in international publication Authors: Guillen-Del-Castillo, Alfredo, Tolosa-Vilella, Carles, Alonso-Vila, Serafin, Fonollosa-Pla, Vicente, Selva-O'Callaghan, Albert, Callejas-Moraga, Eduardo L, Simeon-Aznar, Carmen Pilar et al. DOI: 10.1186/s13075-018-1775-9
PMID: 29322678 Journal: International Journal of Rheumatic Diseases Year: 2017 Reference: Int J Rheum Dis. 2017 Nov;20(11):1865-1867. doi: 10.1111/1756-185X.12739. Epub 2015 Sep 10. Impact factor: 2.624 Publication type: Letter or abstract Authors: Hernandez-Gonzalez, Manuel, Solans-Laque, Roser, Bujan-Rivas, Segundo, Vilardell-Tarres, Miquel, Martinez-Valle, Fernando, Fernandez-Codina, Andreu et al. DOI: 10.1111/1756-185X.12739
PMID: 30416569 Journal: European cardiology Year: 2017 Reference: Eur Cardiol. 2017 Dec;12(2):99. doi: 10.15420/ecr.2017:23:8. Impact factor: Publication type: Letter or abstract Authors: Perez-Rodon, Jordi, Galve, Enrique, Perez-Bocanegra, Carmen, Soriano-Sanchez, Teresa, Recio-Iglesias, Jesus, Domingo-Baldrich, Eva, Alzola-Guevara, Mila, Marsal, Josep Ramon, Ribera-Sole, Aida, Garcia-Moreno, Laura Gutierrez et al. DOI: 10.15420/ecr.2017:23:8
PMID: 27935079 Journal: MUSCLE & NERVE Year: 2017 Reference: Muscle Nerve. 2017 Sep;56(3):386-392. doi: 10.1002/mus.25507. Epub 2017 Apr 4. Impact factor: 2.713 Publication type: Paper in international publication Authors: Casal-Dominguez, Maria, Pinal-Fernandez, Iago, Mego, Marianela, Accarino, Anna, Jubany, Lluis, Azpiroz, Fernando, Selva-O'Callaghan, Albert et al. DOI: 10.1002/mus.25507
PMID: 27899373 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2017 Reference: Ann Rheum Dis. 2017 Jun;76(6):1042-1050. doi: 10.1136/annrheumdis-2016-209952. Epub 2016 Nov 29. Impact factor: 12.384 Publication type: Paper in international publication Authors: Garcia-Sanchez, I, Brito-Zeron, Pilar, Acar-Denizli, Nihan, Zeher, Margit, Rasmussen, Astrid, Brun, Johan G, Fraile, Guadalupe, Carsons, Steven E, Gheita, Tamer A, Morel, Jacques et al. DOI: 10.1136/annrheumdis-2016-209952
PMID: 26343153 Journal: MEDICINA CLINICA Year: 2016 Reference: Med Clin (Barc). 2016 Jan 1;146(1):21-3. doi: 10.1016/j.medcli.2015.07.002. Epub 2015 Sep 3. Impact factor: 1.267 Publication type: Editorial in national publication Authors: Fonollosa-Pla, Vicent, Simeon-Aznar, Carmen Pilar et al. DOI: 10.1016/j.medcli.2015.07.002
PMID: 26552061 Journal: MOLECULAR MEDICINE Year: 2016 Reference: Mol Med. 2016 Mar;21(1):817-823. doi: 10.2119/molmed.2015.00168. Epub 2015 Nov 3. Impact factor: 3.53 Publication type: Paper in international publication Authors: Villarroya, Francesc, Catalan-Garcia, Marc, Garrabou, Gloria, Moren, Constanza, Guitart-Mampel, Mariona, Gonzalez-Casacuberta, Ingrid, Hernando, Adriana, Gallego-Escuredo, Jose Miquel, Yubero, Delia, Cardellach, Francesc et al. DOI: 10.2119/molmed.2015.00168
PMID: 26454514 Journal: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE Year: 2016 Reference: QJM. 2016 Mar;109(3):205-6. doi: 10.1093/qjmed/hcv196. Epub 2015 Oct 10. Impact factor: 2.824 Publication type: Letter or abstract Authors: Pinal-Fernandez, I, Fonollosa-Pla, V, Selva-O'Callaghan, A et al. DOI: 10.1093/qjmed/hcv196
PMID: 25896534 Journal: PHARMACOGENOMICS JOURNAL Year: 2016 Reference: Pharmacogenomics J. 2016 Apr;16(2):147-50. doi: 10.1038/tpj.2015.31. Epub 2015 Apr 21. Impact factor: 3.784 Publication type: Paper in international publication Authors: Julia, A, Fernandez-Nebro, A, Blanco, F, Ortiz, A, Canete, J D, Maymo, J, Alperi-Lopez, M, Fernandez-Gutierrez, B, Olive, A, Corominas, H et al. DOI: 10.1038/tpj.2015.31
PMID: 25403996 Journal: PHARMACOGENOMICS JOURNAL Year: 2015 Reference: Pharmacogenomics J. 2015 Aug;15(4):322-5. doi: 10.1038/tpj.2014.71. Epub 2014 Nov 18. Impact factor: 4.229 Publication type: Paper in international publication Authors: Julia, A, Ferrandiz, C, Dauden, E, Fonseca, E, Fernandez-Lopez, E, Sanchez-Carazo, J L, Vanaclocha, F, Puig, L, Moreno-Ramirez, D, Lopez-Estebaranz, J L et al. DOI: 10.1038/tpj.2014.71
PMID: 25651522 Journal: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE Year: 2015 Reference: Int J Clin Pract. 2015 Aug;69(8):829-39. doi: 10.1111/ijcp.12616. Epub 2015 Feb 4. Impact factor: 2.566 Publication type: Paper in international publication Authors: Satue, J A, Davila, M F, Diez-Manglano, J, Epelde, F, Formiga, F, Gallego, J, Gonzalez-Franco, A, Guisado, M E, Herrero, A, Lopez-Castellanos, G et al. DOI: 10.1111/ijcp.12616
PMID: 26110683 Journal: Current Opinion in Allergy and Clinical Immunology Year: 2015 Reference: Curr Opin Allergy Clin Immunol. 2015 Aug;15(4):329-36. doi: 10.1097/ACI.0000000000000184. Impact factor: 3.574 Publication type: Review in international publication Authors: Sala-Cunill, Anna, Cardona, Victoria et al. DOI: 10.1097/ACI.0000000000000184
PMID: 26346472 Journal: Drug Design Development and Therapy Year: 2015 Reference: Drug Des Devel Ther. 2015 Aug 25;9:4909-15. doi: 10.2147/DDDT.S56004. eCollection 2015. Impact factor: 3.028 Publication type: Review in international publication Authors: Labrador-Horrillo, Moises, Ferrer, Marta et al. DOI: 10.2147/DDDT.S56004
PMID: 24120109 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 Mar 20;142(6):275-8. doi: 10.1016/j.medcli.2013.07.022. Epub 2013 Oct 8. Impact factor: 1.252 Publication type: Letter or abstract Authors: Garriga-Companys, Silvia, Labrador-Horrillo, Moises et al. DOI: 10.1016/j.medcli.2013.07.022
PMID: 24424187 Journal: AUTOIMMUN REV Year: 2014 Reference: Autoimmun Rev. 2014 Apr-May;13(4-5):379-82. doi: 10.1016/j.autrev.2014.01.019. Epub 2014 Jan 11. Impact factor: 7.095 Publication type: Review in international publication Authors: Pinal-Fernandez, I, Selva-O' Callaghan, A, Grau, J M et al. DOI: 10.1016/j.autrev.2014.01.019
PMID: 25005322 Journal: REV NEUROLOGIA Year: 2014 Reference: Rev Neurol. 2014 Jul 16;59(2):93. Impact factor: 0.926 Publication type: Letter or abstract Authors: Aranda-Rodriguez, Santiago, Marques-Vilallonga, Adalbert, Jimenez-Moreno, Francesc X, Trallero-Araguas, Ernesto et al. DOI:
PMID: 25493569 Journal: PHARMACOGENOMICS Year: 2014 Reference: Pharmacogenomics. 2014 Nov;15(14):1763-1769. doi: 10.2217/pgs.14.125. Impact factor: 3.425 Publication type: Paper in international publication Authors: Blanco, Ricardo, Dominguez, Alfredo Willisch, Mosquera, Jose Antonio, Vela, Paloma, Tornero, Jesus, Sanchez-Fernandez, Simon, Corominas, Hector, Ramirez, Julio, Avila, Gabriela, Alonso, Arnald et al. DOI: 10.2217/pgs.14.125
PMID: 24098674 Journal: PLoS One Year: 2013 Reference: PLoS One. 2013 Sep 30;8(9):e74873. doi: 10.1371/journal.pone.0074873. eCollection 2013. Impact factor: 3.73 Publication type: Paper in international publication Authors: Estivill, Xavier, Rabionet, Raquel, Alegre, Jose, Docampo, Elisa, Collado, Antonio, Escaramis, Georgia, Carbonell, Jordi, Rivera, Javier, Vidal, Javier et al. DOI: 10.1371/journal.pone.0074873
PMID: 23740937 Journal: HUMAN MOLECULAR GENETICS Year: 2013 Reference: Hum Mol Genet. 2013 Oct 1;22(19):4021-9. doi: 10.1093/hmg/ddt248. Epub 2013 Jun 4. Impact factor: 7.692 Publication type: Paper in international publication Authors: Kovacs, Laszlo, Chee, Meng May, Worthington, Jane, Herrick, Arianne, Denton, Christopher, Fonseca, Carmen, Tan, Filemon K, Arnett, Frank, Zhou, Xiaodong, Reveille, John D et al. DOI: 10.1093/hmg/ddt248
PMID: 24645995 Journal: Pain Management Year: 2013 Reference: Pain Manag. 2013 Mar;3(2):119-22. doi: 10.2217/pmt.12.84. Impact factor: 0.86 Publication type: Paper in international publication Authors: Alegre, Jose, Camprubi, Sandra, Garcia-Quintana, Ana et al. DOI: 10.2217/pmt.12.84
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The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
