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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Team

Moisés Labrador Horrillo

Moisés Labrador Horrillo

Main researcher
Systemic Diseases
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Vicenç Fonollosa Pla

Vicenç Fonollosa Pla

Systemic Diseases
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Victòria Cardona Dahl

Victòria Cardona Dahl

Main researcher
Systemic Diseases
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Francesc Miro Mur

Francesc Miro Mur

Postdoctoral researcher
Systemic Diseases
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Galvan Blasco, Paula

Galvan Blasco, Paula

Predoctoral researcher
Systemic Diseases
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Laura Donaire Lancharro

Laura Donaire Lancharro

Research technician
Systemic Diseases
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Moisés Labrador Horrillo

Moisés Labrador Horrillo

Main researcher
Systemic Diseases
Read more
Vicenç Fonollosa Pla

Vicenç Fonollosa Pla

Systemic Diseases
Read more
Victòria Cardona Dahl

Victòria Cardona Dahl

Main researcher
Systemic Diseases
Read more
Francesc Miro Mur

Francesc Miro Mur

Postdoctoral researcher
Systemic Diseases
Read more
Galvan Blasco, Paula

Galvan Blasco, Paula

Predoctoral researcher
Systemic Diseases
Read more
Laura Donaire Lancharro

Laura Donaire Lancharro

Research technician
Systemic Diseases
Read more

Research lines

Cardiac involvement in Churg-Strauss Granulomatosis (EGPE).

Cardiac involvement is one of the most important causes of dead in EGPE. The aim of this study is to investigate the prevalence of silent cardiac involvement in patients with EGPE, and if some chemotaxins (eotaxins 1, 2 and 3) may play a key role in its development, in order to establish an early tretament.

IP: Roser Solans Laque

Cellular microparticles study in women with and without antiphospholipid antibodies with recurrent pregnancy loses and preeclampsia.

Cellular microparticles (CMP) are released depending on the activation and/or the presence of cell apoptosis. They are capable of activating both inflammatory and coagulation pathways. It seems that levels of CMP are higher in healthy pregnant women. A working hypothesis establishes that an increase of CMP levels may be found in recurrent pregnancy loses and preeclampsia. It is thought that their thrombophilic capacity may be higher in those patients with anti-phospholipid antibodies, especially among those with lupus anticoagulant. We want to determine MPC levels in non-pregnant healthy women, pregnant women without previous abnormal obstetric events, women with recurrent pregnancy loses, and women with severe preeclampsia. We are also evaluating whether there are differences related to the presence or absence of antiphospholipid antibodies. Finally, we will also characterize the exact type of CMP (endothelial, platelet-like, leuco-monocyte, and throphoblastic).

IP: Jaume Alijotas Reig

Characterization of inhibitors in patients with acquired haemophilia

Spanish multicenter clinical assay in collaboration with Vall d´Hebrón Hospital Haemophilia Unit and Spanish Society of Thrombosis and Haemostasis. The objective is to characterize the FVIII domains that act as epitopes for autoantibodies in acquired haemophilia, and its relationship with clinical manifestations and treatment of disease.

IP: José Pardos Gea

Construcción de un Predictor Diagnóstico para las enfermedades Inflamatorias mediadas por mecanismos inmunes (predictor-IMID)

Subprograma de apoyo a proyectos singulares y estratégicos 2008-2009

IP: Sara Marsal Barril

Projects

New nanotechnological therapy for Parkinson's disease: nose-to-brain delivery of GBA-polymer nanoconjugates (NANOGBAtoBRAIN)

IP: Marta Martínez Vicente
Collaborators: José Antonio Arranz Amo, Eddie Pradas Gracia, Laura Castillo Ribelles, Clara Carnicer Cáceres, David Moreno Martinez, Jordi Riera Heredia, Marta Montpeyó Garcia-Moreno, Pablo Castillo Sánchez
Funding agency: Fundació "La Caixa"
Funding: 249950
Reference: HR22-00602
Duration: 01/11/2022 - 31/10/2025

(LOCAL-NKs) - Estudio de NK residentes de memoria en tejido para el control de infecciones virales

IP: María José Buzón Gómez
Collaborators: David Perea Pérez, Oriol Ruiz Isant, Nerea Sanchez Gaona, Joan Rey Cano, (LOCAL-NKs) - Estudio de NK residentes de memoria en tejido para el control de infecciones virales, Alba González Robles
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 363000
Reference: PID2021-123321OB-I00
Duration: 01/09/2022 - 31/08/2025

Ministerio de Ciencia

Desarrollo y evaluación de la implantación de una herramienta co-creada para la identificación y notificación por parte del paciente de cuasi-incidentes de seguridad en la atención hospitalaria.

IP: Dimelza Osorio Sánchez
Collaborators: Jesús Martínez Pérez, Karla Salas Gama, Percy Efrain Pantoja Bustillos, Anna Sala Cunill, Roser Martin Campos, Julia Salvador Lodosa, Daniel López Torres, Victoria Valls Comamala, Marta Aguayo Álvarez , Dimelza Osorio Sánchez
Funding agency: Instituto de Salud Carlos III
Funding: 62920
Reference: PI22/00371
Duration: 01/01/2023 - 31/12/2025

Caracterización de las células patogénicas del músculo y piel de pacientes con Dermatomiositis y Síndrome Antisintetasa y estudio de aplicabilidad traslacional.

IP: Ernesto Trallero Araguas
Collaborators: Albert Selva O'Callaghan, Raul Tortosa Mendez, Albert Gil Vila, Gloria Aparicio Español, Adria Aterido Ballonga, Hugo Fernando Avalos Bogado
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI22/00708
Duration: 01/01/2023 - 31/12/2025

Publications

Impact of the COVID-19 pandemic in the early-onset colorectal cancer.

PMID: 37031602
Journal: Translational Oncology
Year: 2023
Reference: Transl Oncol. 2023 Jun;32:101668. doi: 10.1016/j.tranon.2023.101668. Epub 2023 Apr 5.
Impact factor:
Publication type: Paper in international publication
Authors: Baraibar, Iosune; Capdevila, Jaume; Castells, Marta R; Castillo, Gloria; Comas, Raquel; Comas, Raquel; Dopazo, Cristina; Elez, Elena; Espin, Eloy; Garcia, Ariadna et al.
DOI: 10.1016/j.tranon.2023.101668

Patient-centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA-EAACI approach.

PMID: 37042071
Journal: ALLERGY
Year: 2023
Reference: Allergy. 2023 Apr 11. doi: 10.1111/all.15740.
Impact factor:
Publication type: Review in international publication
Authors: Amaral, Rita; Ansotegui, Ignacio J; Anto, Josep M; Barbara, Cristina; Bedbrook, Anna; Bergmann, Karl C; Bewick, Michael; Blain, Hubert; Bonini, Matteo; Bosnic-Anticevich, Sinthia et al.
DOI: 10.1111/all.15740

Anti-U11/U12 Antibodies as a Rare but Important Biomarker in Patients with Systemic Sclerosis: A Narrative Review.

PMID: 37046475
Journal: Diagnostics
Year: 2023
Reference: Diagnostics (Basel). 2023 Mar 27;13(7):1257. doi: 10.3390/diagnostics13071257.
Impact factor:
Publication type: Review in international publication
Authors: Bentow, Chelsea; Beretta, Lorenzo; Callejas-Moraga, Eduardo; Fonollosa-Pla, Vicent; Fritzler, Marvin J; Guillen-Del-Castillo, Alfredo; Mahler, Michael; Marin, Ana; Palterer, Boaz; Perurena-Prieto, Janire et al.
DOI: 10.3390/diagnostics13071257

INMUNOCAT study: The impact of molecular diagnosis on immunotherapy prescription in pollen polysensitized patients from Catalonia.

PMID: 37227418
Journal: Clinical and Translational Allergy
Year: 2023
Reference: Clin Transl Allergy. 2023 May;13(5):e12246. doi: 10.1002/clt2.12246.
Impact factor:
Publication type: Paper in international publication
Authors: Asensio, O; Bartra, J; Belmonte, J; Bobolea, I; De Linares, C; Farrarons, L; Garriga-Baraut, Teresa; Labrador-Horrillo, Moises; Miquel, S; Moncin, M M San Miguel et al.
DOI: 10.1002/clt2.12246

Recurrent thrombosis as a clinical presentation of Whipple disease.

PMID: 35144962
Journal: BMJ case reports
Year: 2022
Reference: BMJ Case Rep. 2022 Feb 10;15(2). pii: 15/2/e247020. doi: 10.1136/bcr-2021-247020.
Impact factor: 0
Publication type: Letter or abstract
Authors: Solans-Laque, Roser; Terrones-Peinador, Maria; Eremiev-Eremiev, Simeon; Pigrau-Serrallach, Carlos et al.
DOI: 10.1136/bcr-2021-247020

Clinical and therapeutic value of the adjusted Global Antiphospholipid Syndrome Score in primary obstetric antiphospholipid syndrome.

PMID: 35157809
Journal: LUPUS
Year: 2022
Reference: Lupus. 2022 Mar;31(3):354-362. doi: 10.1177/09612033221078223. Epub 2022 Feb 14.
Impact factor: 2.911
Publication type: Paper in international publication
Authors: Udry, Sebastian; Perez, Stephanie Morales; Belizna, Cristina; Aranda, Federico; Esteve-Valverde, Enrique; Wingeyer, Silvia Peres; Fernandez-Romero, Diego S; Latino, Jose O; de Larranaga, Gabriela; Alijotas-Reig, Jaume et al.
DOI: 10.1177/09612033221078223

Pulmonary involvement in Sjogren's syndrome.

PMID: 34392987
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin (Barc). 2022 Feb 25;158(4):181-185. doi: 10.1016/j.medcli.2021.06.016. Epub 2021 Aug 13.
Impact factor: 1.725
Publication type: Review in national publication
Authors: Mestre-Torres, Jaume; Solans-Laque, Roser et al.
DOI: 10.1016/j.medcli.2021.06.016

Pathogenesis, Diagnosis and Management of Obstetric Antiphospholipid Syndrome: A Comprehensive Review.

PMID: 35160128
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Jan 28;11(3). pii: jcm11030675. doi: 10.3390/jcm11030675.
Impact factor: 4.242
Publication type: Review in international publication
Authors: Alijotas-Reig, Jaume; Esteve-Valverde, Enrique; Anunciacion-Llunell, Ariadna; Marques-Soares, Joana; Pardos-Gea, Josep; Miro-Mur, Francesc et al.
DOI: 10.3390/jcm11030675

Implantation of a biochemical and genetic screening programme for family hypercholesterolaemia. Collaboration between the clinical laboratory and lipid units: Design of the ARIAN Project.

PMID: 34090714
Journal: Clinica e investigacion en arteriosclerosis : publ
Year: 2021
Reference: Clin Investig Arterioscler. 2021 Nov-Dec;33(6):289-295. doi: 10.1016/j.arteri.2021.03.004. Epub 2021 Jun 3.
Impact factor: 0
Publication type: Paper in national publication
Authors: Perez, Enrique Ruiz, Albarran, Olga Gonzalez, Puebla, Mercedes Herranz, Robles, Carolina Puertas, Anguila, Silvia Campos, Ruiz, Joan Lima, Ruiz, Armando Raul Guerra, Hernandez, Jose Luis Hernandez, Lario, Jose Vicente Garcia, Busto, Pablo Gonzalez et al.
DOI: 10.1016/j.arteri.2021.03.004

Childhood-onset of primary Sjogren's syndrome: phenotypic characterization at diagnosis of 158 children.

PMID: 33493333
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Oct 2;60(10):4558-4567. doi: 10.1093/rheumatology/keab032.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Hinrichs, Anneline, Gandolfo, Saviana, Hashimoto, Kunio, Hernandez-Molina, Gabriela, Hofauer, Benedikt, Mendieta-Zeron, Samara, Rasmussen, Astrid, Sandhya, Pulukool, Sene, Damien, Trevisani, Virginia Fernandes Moca et al.
DOI: 10.1093/rheumatology/keab032

DERMATOMYOSITIS.

PMID: 34247244
Journal: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Year: 2021
Reference: QJM. 2021 Dec 20;114(10):749. doi: 10.1093/qjmed/hcab187.
Impact factor: 3.21
Publication type: Letter or abstract
Authors: Selva-O'Callaghan, A, Pardos-Gea, J, Marques-Soares, J R et al.
DOI: 10.1093/qjmed/hcab187

COVID GEAS: COVID-19 National Survey in Patients With Systemic Autoimmune Diseases.

PMID: 35155485
Journal: Frontiers in Medicine
Year: 2021
Reference: Front Med (Lausanne). 2022 Jan 27;8:808608. doi: 10.3389/fmed.2021.808608. eCollection 2021.
Impact factor: 5.093
Publication type: Paper in international publication
Authors: Saez, Luis, Pallares, Lucio, Velilla, Jose, Marin, Adela, Martinez-Lostao, Luis, Simeon, Carmen Pilar, Fanlo, Patricia, Gracia, Borja Del Carmelo et al.
DOI: 10.3389/fmed.2021.808608

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.

PMID: 31851795
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2020
Reference: N Engl J Med. 2020 Jan 16;382(3):211-221. doi: 10.1056/NEJMoa1912196. Epub 2019 Dec 18.
Impact factor: 74.699
Publication type: Paper in international publication
Authors: McCune, W J, Najam, S, Waller, P, Suh, C-H, Worm, M, Kivitz, A, Snyder, A, Kempf, P, Kenney, H, Scheinberg, M et al.
DOI: 10.1056/NEJMoa1912196

Expert Consensus on a Set of Outcomes to Assess the Effectiveness of Biologic Treatment in Psoriatic Arthritis: The MERECES Study.

PMID: 32007930
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2020
Reference: J Rheumatol. 2020 Nov 1;47(11):1637-1643. doi: 10.3899/jrheum.191056. Epub 2020 Feb 1.
Impact factor: 3.35
Publication type: Paper in international publication
Authors: Sanchez-Carazo, Jose L, Rodriguez, Miguel J, Ruiz, Miguel, Lizan, Luis, Belinchon, Isabel, Chamizo, Eugenio, Babio, Jesus, Almodovar, Raquel, Rio, Tamara Del, Poveda, Jose Luis et al.
DOI: 10.3899/jrheum.191056

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.

PMID: 32341526
Journal: NATURE GENETICS
Year: 2020
Reference: Nat Genet. 2020 May;52(5):482-493. doi: 10.1038/s41588-020-0610-9. Epub 2020 Apr 27.
Impact factor: 27.603
Publication type: Paper in international publication
Authors: Hakonarson, Hakon, Brueggeman, Leo, Breen, Gerome, Bulik, Cynthia M, Arenas, Ernest, Hjerling-Leffler, Jens, Sullivan, Patrick F, Adan, Roger, Alfredsson, Lars, Ando, Tetsuya et al.
DOI: 10.1038/s41588-020-0610-9

Anti-TIF-1gamma Antibody Detection Using a Commercial Kit vs In-House Immunoblot: Usefulness in Clinical Practice.

PMID: 33613568
Journal: Frontiers in Immunology
Year: 2020
Reference: Front Immunol. 2021 Feb 1;11:625896. doi: 10.3389/fimmu.2020.625896. eCollection 2020.
Impact factor: 5.085
Publication type: Paper in international publication
Authors: Mariscal, Anais, Milan, Milena, Baucells, Andres, Martinez, Maria Angeles, Guillen, Andrea Garcia, Trallero-Araguas, Ernesto, Alvarado-Cardenas, Marcelo, Martinez-Martinez, Laura, Alserawan, Leticia, Franco-Leyva, Teresa et al.
DOI: 10.3389/fimmu.2020.625896

Myalgic encephalomyelitis/chronic fatigue Syndrome (ME/CFS): Investigating care practices pointed out to disparities in diagnosis and treatment across European Union.

PMID: 31805176
Journal: PLoS One
Year: 2019
Reference: PLoS One. 2019 Dec 5;14(12):e0225995. doi: 10.1371/journal.pone.0225995. eCollection 2019.
Impact factor: 2.776
Publication type: Paper in international publication
Authors: Sirbu, Carmen Adella, Authier, F Jerome, Sakkas, Giorgos K, Pheby, Derek, Efrim-Budisteanu, Magdalena, Strand, Elin B, Nacul, Luis, Mengshoel, Anne Marit, Helland, Ingrid B, Grabowski, Patricia et al.
DOI: 10.1371/journal.pone.0225995

Simplification of the Barthel scale for screening for frailty and severe dependency in polypathological patients.

PMID: 31126711
Journal: REVISTA CLINICA ESPANOLA
Year: 2019
Reference: Rev Clin Esp. 2019 Nov;219(8):433-439. doi: 10.1016/j.rce.2019.04.005. Epub 2019 May 21.
Impact factor: 1.043
Publication type: Paper in national publication
Authors: Barbe Gil-Ortega, Jose, Baron-Franco, Bosco, Bernabeu-Wittel, Maximo, de la Calle-Cabrera, Cristina, Cassani-Garza, Manuel, Castillo-Blasco, Manuela, Diez, Felipe, Diez-Manglano, Jesus, Escalera-Zalvide, Alberto, Feliu-Mazaria, Luis et al.
DOI: 10.1016/j.rce.2019.04.005

Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.

PMID: 30911372
Journal: Clinical and Translational Allergy
Year: 2019
Reference: Clin Transl Allergy. 2019 Mar 11;9:16. doi: 10.1186/s13601-019-0252-0. eCollection 2019.
Impact factor: 4.232
Publication type: Review in international publication
Authors: Anto, J M, Bousquet, J, Bedbrook, A, Czarlewski, W, Onorato, G L, Rodriguez-Zagal, E, Valiulis, A, Dubakiene, R, Emuzyte, R, Kvedariene, V et al.
DOI: 10.1186/s13601-019-0252-0

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status.

PMID: 31719529
Journal: Nature Communications
Year: 2019
Reference: Nat Commun. 2019 Nov 12;10(1):5120. doi: 10.1038/s41467-019-12515-9.
Impact factor: 11.878
Publication type: Paper in international publication
Authors: Ramirez, Giuseppe A, Rewerska, Barbara, Schett, Georg, Sinico, Renato A, Szczeklik, Wojciech, Tesar, Vladimir, Vukcevic, Damjan, Terrier, Benjamin, Watts, Richard A, Vaglio, Augusto et al.
DOI: 10.1038/s41467-019-12515-9

The combination of IL-6 and its soluble receptor is associated with the response of rheumatoid arthritis patients to tocilizumab.

PMID: 29157669
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2018
Reference: Semin Arthritis Rheum. 2018 Jun;47(6):757-764. doi: 10.1016/j.semarthrit.2017.10.022. Epub 2017 Nov 20.
Impact factor: 4.498
Publication type: Paper in international publication
Authors: Corominas, Hector, Diaz-Torne, Cesar, Ortiz, Maria Dels Angels, Moya, Patricia, Hernandez, Maria Victoria, Reina, Delia, Castellvi, Ivan, De Agustin, Juan Jose, Fuente, Diana de la, Canto, Elisabet et al.
DOI: 10.1016/j.semarthrit.2017.10.022

Challenges in the implementation of the EAACI AIT guidelines: A situational analysis of current provision of allergen immunotherapy.

PMID: 28850687
Journal: ALLERGY
Year: 2018
Reference: Allergy. 2018 Apr;73(4):827-836. doi: 10.1111/all.13264. Epub 2017 Dec 12.
Impact factor: 7.361
Publication type: Paper in international publication
Authors: Varga, E M, Ryan, D, Gerth van Wijk, R, Angier, E, Kristiansen, M, Zaman, H, Sheikh, A, Cardona, V, Vidal, C, Warner, A et al.
DOI: 10.1111/all.13264

Severe anaphylaxis due to crocodile-meat allergy exhibiting wide cross-reactivity with fish allergens.

PMID: 28923489
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2018
Reference: J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):669-670.e1. doi: 10.1016/j.jaip.2017.07.015. Epub 2017 Sep 8.
Impact factor: 6.966
Publication type: Paper in international publication
Authors: Haroun-Diaz, Elisa, Blanca-Lopez, Natalia, Vazquez de la Torre, Maria, Ruano, Francisco Javier, Somoza Alvarez, Maria Luisa, Labrador Horrillo, Moises, Bartolome, Borja, Blanca, Miguel, Canto Diez, Gabriela et al.
DOI: 10.1016/j.jaip.2017.07.015

Timing of onset affects arthritis presentation pattern in antisyntethase syndrome.

PMID: 28770709
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2018
Reference: Clin Exp Rheumatol. 2018 Jan-Feb;36(1):44-49. Epub 2017 Jul 26.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Emmi, Giacomo, Rojas-Serrano, Jorge, Perez-Roman, Diana Isabel, Bauhammer, Jutta, Fiehn, Christoph, Neri, Rossella, Barsotti, Simone, Lorenz, Hannes M, Doria, Andrea, Ghirardello, Anna et al.
DOI:

Management of chronic spontaneous urticaria in routine clinical practice: A Delphi-method questionnaire among specialists to test agreement with current European guidelines statements.

PMID: 28029407
Journal: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Year: 2017
Reference: Allergol Immunopathol (Madr). 2017 Mar - Apr;45(2):134-144. doi: 10.1016/j.aller.2016.06.007. Epub 2016 Oct 28.
Impact factor: 1.439
Publication type: Paper in international publication
Authors: Gimenez-Arnau, A, Ferrer, M, Bartra, J, Jauregui, I, Labrador-Horrillo, M, Frutos, J Ortiz de, Silvestre, J F, Sastre, J, Velasco, M, Valero, A et al.
DOI: 10.1016/j.aller.2016.06.007

Food allergy in Catalonia: Clinical manifestations and its association with airborne allergens.

PMID: 27592278
Journal: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Year: 2017
Reference: Allergol Immunopathol (Madr). 2017 Jan - Feb;45(1):48-54. doi: 10.1016/j.aller.2016.06.004. Epub 2016 Aug 31.
Impact factor: 1.439
Publication type: Paper in international publication
Authors: Basagana, M, Sanchez-Lopez, J, Gazquez, V, Rubira, N, Valdesoiro, L, Guilarte, M, Garcia-Moral, A, Depreux, N, Soto-Retes, L, De Molina, M et al.
DOI: 10.1016/j.aller.2016.06.004

Omalizumab use during pregnancy for chronic spontaneous urticaria (CSU): report of two cases.

PMID: 27868240
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2017
Reference: J Eur Acad Dermatol Venereol. 2017 May;31(5):e245-e246. doi: 10.1111/jdv.14034. Epub 2016 Nov 20.
Impact factor: 3.528
Publication type: Letter or abstract
Authors: Gonzalez-Medina, M, Curto-Barredo, L, Labrador-Horrillo, M, Gimenez-Arnau, A et al.
DOI: 10.1111/jdv.14034

Cardiac tamponade and severe pericardial effusion in systemic sclerosis: report of nine patients and review of the literature.

PMID: 27943614
Journal: International Journal of Rheumatic Diseases
Year: 2017
Reference: Int J Rheum Dis. 2017 Oct;20(10):1582-1592. doi: 10.1111/1756-185X.12952. Epub 2016 Dec 10.
Impact factor: 2.624
Publication type: Review in international publication
Authors: Fernandez Morales, Alejandro, Iniesta, Nerea, Fernandez-Codina, Andreu, Vaz de Cunha, Joana, Perez Romero, Teresa, Hurtado Garcia, Robert, Simeon-Aznar, Carmen Pilar, Fonollosa, Vicent, Cervera, Ricard, Espinosa, Gerard et al.
DOI: 10.1111/1756-185X.12952

Component-resolved diagnosis in anaphylaxis.

PMID: 26945180
Journal: Current Opinion in Allergy and Clinical Immunology
Year: 2016
Reference: Curr Opin Allergy Clin Immunol. 2016 Jun;16(3):244-9. doi: 10.1097/ACI.0000000000000261.
Impact factor: 2.771
Publication type: Review in international publication
Authors: Ansotegui, Ignacio J, Cardona, Victoria et al.
DOI: 10.1097/ACI.0000000000000261

Particularities of allergy in the Tropics.

PMID: 27386040
Journal: The World Allergy Organization journal
Year: 2016
Reference: World Allergy Organ J. 2016 Jun 27;9:20. doi: 10.1186/s40413-016-0110-7. eCollection 2016.
Impact factor: 0
Publication type: Review in international publication
Authors: Ansotegui, Ignacio, Caraballo, Luis, Zakzuk, Josefina, Lee, Bee Wah, Acevedo, Nathalie, Soh, Jian Yi, Sanchez-Borges, Mario, Hossny, Elham, Garcia, Elizabeth, Rosario, Nelson et al.
DOI: 10.1186/s40413-016-0110-7

Relevance of Allergenic Sensitization to Cynodon dactylon and Phragmites communis: Cross-reactivity With Pooideae Grasses.

PMID: 27763856
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2016
Reference: J Investig Allergol Clin Immunol. 2016;26(5):295-303. doi: 10.18176/jiaci.0049.
Impact factor: 2.131
Publication type: Paper in international publication
Authors: Lopez-Matas, M A, Moya, R, Cardona, V, Valero, A, Gaig, P, Malet, A, Vinas, M, Garcia-Moral, A, Labrador, M, Alcoceba, E et al.
DOI: 10.18176/jiaci.0049

Safe and Time-Saving Desensitization Protocol to Intravenous Etoposide.

PMID: 27393789
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2016
Reference: J Allergy Clin Immunol Pract. 2016 Jul-Aug;4(4):793-4. doi: 10.1016/j.jaip.2016.03.026.
Impact factor: 5.429
Publication type: Letter or abstract
Authors: Gomez-Duque, Manuel, Sala-Cunill, Anna, Farriols, Anna, Cardona, Victoria, Luengo, Olga et al.
DOI: 10.1016/j.jaip.2016.03.026

Inflammatory myopathy: diagnosis and clinical course, specific clinical scenarios and new complementary tools.

PMID: 25926278
Journal: Expert Review of Clinical Immunology
Year: 2015
Reference: Expert Rev Clin Immunol. 2015 Jun;11(6):737-47. doi: 10.1586/1744666X.2015.1035258. Epub 2015 Apr 30.
Impact factor: 2.484
Publication type: Paper in international publication
Authors: Selva-O'Callaghan, Albert, Trallero-Araguas, Ernesto, Martinez, Maria Angeles, Labrador-Horrillo, Moises, Pinal-Fernandez, Iago, Grau-Junyent, Josep Maria, Juarez, Candido et al.
DOI: 10.1586/1744666X.2015.1035258

New diagnostic criteria for fibromyalgia: Here to stay?

PMID: 25443560
Journal: Reumatologia clinica
Year: 2015
Reference: Reumatol Clin. 2015 Jul-Aug;11(4):210-4. doi: 10.1016/j.reuma.2014.07.008. Epub 2014 Oct 23.
Impact factor: 0
Publication type: Paper in national publication
Authors: Moyano, Sebastian, Kilstein, Jorge Guillermo, Alegre de Miguel, Cayetano et al.
DOI: 10.1016/j.reuma.2014.07.008

Pleural irregularity, a new ultrasound sign for the study of interstitial lung disease in systemic sclerosis and antisynthetase syndrome.

PMID: 26315813
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2015
Reference: Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S136-41. Epub 2015 Aug 27.
Impact factor: 2.724
Publication type: Paper in international publication
Authors: Pallisa-Nunez, Esther, Selva-O'Callaghan, Albert, Castella-Fierro, Eva, Simeon-Aznar, Carmen Pilar, Fonollosa-Pla, Vicent, Vilardell-Tarres, Miquel, Pinal-Fernandez, Iago et al.
DOI:

Analysis of employment rate and social status in young adults with childhood-onset rheumatic disease in Catalonia.

PMID: 26162373
Journal: Pediatric Rheumatology
Year: 2015
Reference: Pediatr Rheumatol Online J. 2015 Jul 11;13:29. doi: 10.1186/s12969-015-0026-8.
Impact factor: 1.607
Publication type: Paper in international publication
Authors: Modesto Caballero, Consuelo, Navarro-Cendejas, Jose, Diaz-Mendoza, Ana Carolina et al.
DOI: 10.1186/s12969-015-0026-8

Diagnosis and allergen immunotherapy treatment of polysensitised patients with respiratory allergy in Spain: an Allergists' Consensus.

PMID: 25699172
Journal: Clinical and Translational Allergy
Year: 2014
Reference: Clin Transl Allergy. 2014 Nov 7;4:36. doi: 10.1186/2045-7022-4-36. eCollection 2014.
Impact factor: 0
Publication type: Paper in international publication
Authors: Vidal, Carmen, Enrique, Ernesto, Gonzalo, Angeles, Moreno, Carmen, Tabar, Ana I, Expert Clinical Participants, Cardona, Victòria et al.
DOI: 10.1186/2045-7022-4-36

Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus.

PMID: 24946689
Journal: ARTHRITIS RES THER
Year: 2014
Reference: Arthritis Res Ther. 2014 Jun 19;16(3):R128. doi: 10.1186/ar4585.
Impact factor: 4.117
Publication type: Paper in international publication
Authors: Skopouli, Fotini N, Alonso-Perez, Elisa, Suarez-Gestal, Marian, Calaza, Manuel, Blanco, Francisco J, Suarez, Ana, Santos, Maria Jose, Papasteriades, Chryssa, Carreira, Patricia, Pullmann, Rudolf et al.
DOI: 10.1186/ar4585

Diagnosis and classification of sporadic inclusion body myositis (sIBM).

PMID: 24424185
Journal: AUTOIMMUN REV
Year: 2014
Reference: Autoimmun Rev. 2014 Apr-May;13(4-5):363-6. doi: 10.1016/j.autrev.2014.01.016. Epub 2014 Jan 12.
Impact factor: 7.095
Publication type: Review in international publication
Authors: Catalan, M, Selva-O'Callaghan, A, Grau, J M et al.
DOI: 10.1016/j.autrev.2014.01.016

Groove sign in eosinophilic fasciitis.

PMID: 25043386
Journal: LANCET
Year: 2014
Reference: Lancet. 2014 Nov 15;384(9956):1774. doi: 10.1016/S0140-6736(14)60526-2. Epub 2014 Jul 17.
Impact factor: 39.207
Publication type: Letter or abstract
Authors: Pinal-Fernandez, Iago, Callejas-Moraga, Eduardo Luis, Roade-Tato, Maria Luisa, Simeon-Aznar, Carmen Pilar et al.
DOI: 10.1016/S0140-6736(14)60526-2

Evidence of association of the NLRP1 gene with giant cell arteritis.

PMID: 23253924
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2013
Reference: Ann Rheum Dis. 2013 Apr;72(4):628-30. doi: 10.1136/annrheumdis-2012-202609. Epub 2012 Dec 19.
Impact factor: 9.111
Publication type: Letter or abstract
Authors: Serrano, Aurora, Carmona, F David, Castaneda, Santos, Solans, Roser, Hernandez-Rodriguez, Jose, Cid, Maria C, Prieto-Gonzalez, Sergio, Miranda-Filloy, Jose A, Rodriguez-Rodriguez, Luis, Morado, Inmaculada C et al.
DOI: 10.1136/annrheumdis-2012-202609

Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.

PMID: 23946333
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2013
Reference: Ann Rheum Dis. 2013 Nov;72(11):1882-6. doi: 10.1136/annrheumdis-2013-203641. Epub 2013 Aug 14.
Impact factor: 9.111
Publication type: Paper in international publication
Authors: Braun, N, Latus, J, Molberg, O, Lie, B A, Moosig, F, Witte, T, Morgan, A W, Gonzalez-Gay, M A, Martin, J, Raya, E et al.
DOI: 10.1136/annrheumdis-2013-203641

HLA and non-HLA genes in Behcet's disease: a multicentric study in the Spanish population.

PMID: 24286189
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2013
Reference: Arthritis Res Ther. 2013 Oct 4;15(5):R145. doi: 10.1186/ar4328.
Impact factor: 4.302
Publication type: Paper in international publication
Authors: Camps, Teresa, Montes-Cano, Marco Antonio, Conde-Jaldon, Marta, Garcia-Lozano, Jose Raul, Ortiz-Fernandez, Lourdes, Ortego-Centeno, Norberto, Castillo-Palma, Maria Jesus, Espinosa, Gerard, Grana-Gil, Genaro, Gonzalez-Gay, Miguel Angel et al.
DOI: 10.1186/ar4328

Is faster safer? Cluster versus short conventional subcutaneous allergen immunotherapy.

PMID: 24283840
Journal: Immunotherapy
Year: 2013
Reference: Immunotherapy. 2013 Dec;5(12):1295-303. doi: 10.2217/imt.13.133.
Impact factor: 2.393
Publication type: Paper in international publication
Authors: Quiralte, Joaquin, Justicia, Jose L, Cardona, Victoria, Davila, Ignacio, Moreno, Estefania, Ruiz, Berta, Garcia, Mario A et al.
DOI: 10.2217/imt.13.133

Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus.

PMID: 23217273
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2012
Reference: Arthritis Res Ther. 2012 Dec 7;14(6):R265. doi: 10.1186/ar4111.
Impact factor: 4.445
Publication type: Paper in international publication
Authors: Ordi-Ros, Josep, Vilardell-Tarres, Miquel, Avila, Gabriela, Cortes-Hernandez, Josefina et al.
DOI: 10.1186/ar4111

Research needs in allergy: an EAACI position paper, in collaboration with EFA.

PMID: 23121771
Journal: Clinical and translational allergy
Year: 2012
Reference: Clin Transl Allergy. 2012 Nov 2;2(1):21. doi: 10.1186/2045-7022-2-21.
Impact factor:
Publication type: Letter or abstract
Authors: Mazon, Angel, Grattan, Clive, Heffler, Enrico, Hellings, Peter W, Jutel, Marek, Knol, Edward, Lotvall, Jan, Muraro, Antonella, Poulsen, Lars K, Roberts, Graham et al.
DOI: 10.1186/2045-7022-2-21

EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy.

PMID: 23110958
Journal: Clinical & Translational Oncology
Year: 2012
Reference: Clin Transl Allergy. 2012 Oct 30;2(1):20. doi: 10.1186/2045-7022-2-20.
Impact factor: 1.327
Publication type: Paper in international publication
Authors: Demoly, Pascal, Gerth van Wijk, Roy, Bousquet, Jean, Sheikh, Aziz, Frew, Anthony, Scadding, Glenis, Bachert, Claus, Malling, Hans J, Valenta, Rudolph, Bilo, Beatrice et al.
DOI: 10.1186/2045-7022-2-20

alpha1-Antitrypsin in Fibromyalgia: Results of a Randomized, Placebo-Controlled, Double-Blind and Crossover Pilot Trial.

PMID: 22190533
Journal: Musculoskeletal care
Year: 2012
Reference: Musculoskeletal Care. 2012 Sep;10(3):178-83. doi: 10.1002/msc.1000. Epub 2011 Dec 22.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , et al.
DOI: 10.1002/msc.1000

Allergic diseases in the elderly.

PMID: 22409889
Journal: Clinical and translational allergy
Year: 2011
Reference: Clin Transl Allergy. 2011 Oct 17;1(1):11.
Impact factor:
Publication type: Letter or abstract
Authors: Cardona, Victoria, Guilarte, Mar, Luengo, Olga, Labrador-Horrillo, Moises, Sala-Cunill, Anna, Garriga, Teresa et al.
DOI: 10.1186/2045-7022-1-11

Infections in patients treated with tumor necrosis factor antagonists: incidence, etiology and mortality in the BIOBADASER registry.

PMID: 21514606
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Nov 12;137(12):533-40. Epub 2011 Apr 22.
Impact factor: 1.413
Publication type: Paper in national publication
Authors: Montoro, Maria, Montesinos, Dolores, Perez-Pampin, Eva, Vela, Paloma, Maiz, Olga, Ortiz, Ana Maria, Tomero, Eva, Abreu, Paloma, Granados, Isabel, Ruiz, Francisco Javier Manero et al.
DOI: 10.1016/j.medcli.2010.11.032

[Consensus on the Use of Rituximab in Rheumatoid Arthritis. A document with evidence-based recommendations. Grupo de Expertos en Rituximab. ].

PMID: 21794777
Journal: Reumatologia clinica
Year: 2011
Reference: Reumatol Clin. 2011 Jan-Feb;7(1):30-44. Epub 2010 Dec 17.
Impact factor:
Publication type: Letter or abstract
Authors: Perez Venegas, Jose J, Tornero Molina, Jesus, Vela, Paloma, Perez Sandoval, Trinidad, Pantoja Zarza, Lucia, Narvaez, Javier, Munoz Fernandez, Santiago, Martin Mola, Emilio, Hernandez, Blanca, Garcia-Arias, Miriam et al.
DOI: 10.1016/j.reuma.2010.11.002

Hepatitis B virus (HBV) reactivation in patients receiving tumor necrosis factor (TNF)-targeted therapy: analysis of 257 cases.

PMID: 22033451
Journal: MEDICINE
Year: 2011
Reference: Medicine (Baltimore). 2011 Nov;90(6):359-71.
Impact factor: 4.256
Publication type: Paper in international publication
Authors: Colodro, A, de Ramon, E, Diaz-Lagares, C, Donate, C, Egurbide, M V, Escoda, O, Galiana, D, Garcia Hernandez, F J, Gil, A, Gomez de la Torre, R et al.
DOI: 10.1097/MD.0b013e3182380a76

High prevalence of growth hormone deficiency in severe fibromyalgia syndromes.

PMID: 20631018
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2010
Reference: J Clin Endocrinol Metab. 2010 Sep;95(9):4331-7. Epub 2010 Jul 14.
Impact factor: 6.202
Publication type: Paper in international publication
Authors: Cuatrecasas, G, Gonzalez, M J, Alegre, C, Sesmilo, G, Fernandez-Sola, J, Casanueva, F F, Garcia-Fructuoso, F, Poca-Dias, V, Izquierdo, J P, Puig-Domingo, M et al.
DOI: 10.1210/jc.2010-0061

Incidence and prevalence of juvenile idiopathic arthritis in Catalonia (Spain).

PMID: 20858139
Journal: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
Year: 2010
Reference: Scand J Rheumatol. 2010 Nov;39(6):472-9. Epub 2010 Sep 21.
Impact factor: 2.507
Publication type: Paper in international publication
Authors: Modesto, C, Anton, J, Rodriguez, B, Bou, R, Arnal, C, Ros, J, Tena, X, Rodrigo, C, Rotes, I, Hermosilla, E et al.
DOI: 10.3109/03009741003742722

[Treatment on fatigue of patients with postpolio syndrome. A systematic review].

PMID: 20473835
Journal: REVISTA DE NEUROLOGIA
Year: 2010
Reference: Rev Neurol. 2010 May 16;50(10):595-602.
Impact factor: 1.234
Publication type: Review in national publication
Authors: Aguila-Maturana, Ana M, Alegre-De Miquel, Cayetano et al.
DOI:

Interdisciplinary consensus document for the treatment of fibromyalgia.

PMID: 21361054
Journal: ACTAS ESPANOLAS DE PSIQUIATRIA
Year: 2010
Reference: Actas Esp Psiquiatr. 2010 Mar;38(2):108-20.
Impact factor: 0.515
Publication type: Review in national publication
Authors: de Miquel, C Alegre, Campayo, J Garcia, Florez, M Tomas, Arguelles, J M Gomez, Tarrio, E Blanco, Montoya, M Gobbo, Martin, A Perez, Salio, A Martinez, Fuentes, J Vidal, Alberch, E Altarriba et al.
DOI:

Ultrasound validity in the measurement of knee cartilage thickness.

PMID: 18684742
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2009
Reference: Ann Rheum Dis. 2009 Aug;68(8):1322-7. Epub 2008 Aug 6.
Impact factor: 7.188
Publication type: Paper in international publication
Authors: Tuneu, R, Uson, J, Naredo, E, Canillas, F, de Agustin, J J, de Miguel, E, Filippucci, E, Iagnocco, A, Moragues, C, Acebes, C et al.
DOI: 10.1136/ard.2008.090738

Pleural fluid mesothelin for the differential diagnosis of exudative pleural effusions.

PMID: 19783262
Journal: MEDICINA CLINICA
Year: 2009
Reference: Med Clin (Barc). 2009 Oct 3;133(12):449-53. Epub 2009 Sep 24.
Impact factor: 1.258
Publication type: Paper in national publication
Authors: Ma Segura, Rosa, Alegre, Jose, Esquerda, Aureli, Ruiz, Eva, Bielsa, Silvia, de Sevilla, Tomas Fernandez, Manuel Porcel, Jose, Aleman, Carmen et al.
DOI: 10.1016/j.medcli.2008.11.047

Guidelines on the clinical usefulness of determination of specific immunoglobulin E to foods.

PMID: 20128415
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2009
Reference: J Investig Allergol Clin Immunol. 2009;19(6):423-32.
Impact factor: 1.254
Publication type: Paper in international publication
Authors: Garcia, B E, Gamboa, P M, Asturias, J A, Lopez-Hoyos, M, Sanz, M L, Caballero, M T, Garcia, J M, Labrador, M, Longo Areso, N, Martinez Quesada, J et al.
DOI:

Comparison of the efficacy and safety of bilastine 20 mg vs desloratadine 5 mg in seasonal allergic rhinitis patients.

PMID: 19132976
Journal: ALLERGY
Year: 2009
Reference: Allergy. 2009 Jan;64(1):158-65.
Impact factor: 6.204
Publication type: Paper in international publication
Authors: Wessel, F, Belder, T de, Sys, L, Schmelzer, A A, van Vliet, J, Van-nieuwenhuyse, P, D'Hont, G, Jorissen, M B M, Gevers, G, Mandazhieva-Pepelanova, M A et al.
DOI: 10.1111/j.1398-9995.2008.01813.x

Thesis

Malaltia Relacionada amb la IgG4

PhD student: Andreu Fernández Codina, Andreu Fernández Codina, Andreu Fernández Codina
Director/s: Inés de Torres Ramirez, Fernando Martínez Valle, Roser Solans Laque
University: Universidad Autònoma de Barcelona
Year: 2019

Evaluación inmunogénica de los tumores de mama triple negativos en relación a la presencia o no de linfocitos intratumorales

PhD student:
Director/s: Javier Cortés Castan, Eva Muñoz Couselo, Vicente Peg Camara
University: Universitat Autònoma de Barcelona
Year: 2019

Factors pronòstics en la pèrdua visual en larteritis de cèl·lules gegants

PhD student: Jaume Mestre Torres
Director/s: Roser Solans Laque
University: Universidad Autònoma de Barcelona
Year: 2019

Relación entre constructos psicológicos y discapacidad funcional y diestrés en subgrupos de pacientes con fibromialgia

PhD student: Sara Nieves Maurel Ibáñez
Director/s: José Alegre Martin
University: Universidad Autònoma de Barcelona
Year: 2018

Blog

News

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.

The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.