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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Team

Olga Luengo Sanchez

Olga Luengo Sanchez

Systemic Diseases
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Roser Solans Laque

Roser Solans Laque

Main researcher
Systemic Diseases
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Segundo Bujan Rivas

Segundo Bujan Rivas

Systemic Diseases
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Olga Luengo Sanchez

Olga Luengo Sanchez

Systemic Diseases
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Roser Solans Laque

Roser Solans Laque

Main researcher
Systemic Diseases
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Segundo Bujan Rivas

Segundo Bujan Rivas

Systemic Diseases
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Research lines

MYOGEN study. Genome Wide Association study in myositis.

We are currently enrolled in this worldwide study to detect global genetic alterations in patients with myositis. Twenty centres from Europe and United States participate in this study. We contribute to add the genetic information of the patients from our population. Professor Frederick W. Miller (Bethesda, USA) and Dr. Ingrid Lundberg (Stockholm, Sweden) lead the project.

IP: Albert Selva O'Callaghan

Paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria is a under diagnosed disease due to its low prevalence and the fact that occasionally debuts as an atypical form. Thrombosis of atypical localization, moreover associated to anemia of unknown origin requires screening for HPN.

IP: José Pardos Gea

Pathogenic role of cellular microparticles and anti-phospholipid/anti-cofactor antibodies in recurrent implantation failures related to In Vitro Fertilization (IVF).

The prevalence of failed IVF is high or very high. Besides problems intrinsic to the technique, we know almost nothing about the possible underlying causes. Anti-phospholipid/anti-cofactor (aPL/aCF) antibodies have been associated to several obstetric complications. Nevertheless, the role that these aPL/aCF antibodies may have in failed IVF is not well defined. With this randomized study we want to understand better the use that these antibodies may have on a clinical daily basis. Along with the microparticles analysis, we could end up by finding several elements that might act as risk markers; in turn, it might even help us to fine-tune the currently used therapeutic approaches.

IP: Jaume Alijotas Reig

Predictive kit to detect the possible establishment of late adverse effects related to bioimplants used in clinical practice.

A high variability in the prevalence of adverse effects with an immunologic basis seems to be related with any implant used in clinical practice. We have managed to find a particular association of HLA haplotypes that increase the risk for developing these effects up to 600 times. We are nowadays working on setting up a safe and reliable biochip or kit which predicts this risk easily in a routine test.

IP: Jaume Alijotas Reig

Publications

Latin American anaphylaxis registry.

PMID: 36816598
Journal: World Allergy Organization Journal
Year: 2023
Reference: World Allergy Organ J. 2023 Feb 5;16(2):100748. doi: 10.1016/j.waojou.2023.100748. eCollection 2023 Feb.
Impact factor:
Publication type: Paper in international publication
Authors: Alacaraz Duarte, Perla; Bernstein, Jonathan A; Cardona, Victoria; Cepeda, Alfonso M; Chavez Vereau, Pierre A; Cherrez-Ojeda, Ivan; Dabove, Fabian; De Falco, Alicia; Diaz, Maria C; Ensina, Luis Felipe et al.
DOI: 10.1016/j.waojou.2023.100748

Expected impact of immunomodulatory agents during pregnancy: A newborn's perspective.

PMID: 36825745
Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY
Year: 2023
Reference: Pediatr Allergy Immunol. 2023 Feb;34(2):e13911. doi: 10.1111/pai.13911.
Impact factor:
Publication type: Review in international publication
Authors: Acevedo, Daniel; Alsina, Laia; Anton, Jordi; Banos, Nuria; Casellas, Manel; Castellanos-Moreira, Raul; Deya-Martinez, Angela; Esteve-Sole, Ana; Garcia-Garcia, Ana; Grados, Dolors et al.
DOI: 10.1111/pai.13911

Infective endocarditis due to Capnocytophaga canimorsus in an immunocompetent patient.

PMID: 36849316
Journal: MEDICINA CLINICA
Year: 2023
Reference: Med Clin (Barc). 2023 May 26;160(10):463-464. doi: 10.1016/j.medcli.2023.01.014. Epub 2023 Feb 26.
Impact factor:
Publication type: Letter or abstract
Authors: Carratala Marin, Pau; Gonzalez Sans, Didac; Guillen-Del-Castillo, Alfredo et al.
DOI: 10.1016/j.medcli.2023.01.014

Pain in individuals with idiopathic inflammatory myopathies, other systemic autoimmune rheumatic diseases, and without rheumatic diseases: A report from the COVAD study.

PMID: 36872076
Journal: International Journal of Rheumatic Diseases
Year: 2023
Reference: Int J Rheum Dis. 2023 Apr;26(4):727-739. doi: 10.1111/1756-185X.14636. Epub 2023 Mar 5.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, Vikas; Agarwal, Vishwesh; Aggarwal, Rohit; Cavagna, Lorenzo; Chatterjee, Tulika; Chinoy, Hector; Cordeiro, Rafael Alves; Day, Jessica; Distler, Oliver; Gheita, Tamer et al.
DOI: 10.1111/1756-185X.14636

A Specialized Therapeutic Approach to Chronic Urticaria Patient's Refractory to H1-Antihistamines Improves the Burden of the Disease. The Spanish AWARE Experience.

PMID: 33349612
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Investig Allergol Clin Immunol. 2022 Jun 20;32(3):191-199. doi: 10.18176/jiaci.0661. Epub 2020 Dec 22.
Impact factor:
Publication type: Paper in international publication
Authors: Bartra, J; Borbujo, J; Ferrer, M; Figueras, I; Gimenez-Arnau, A; Jauregui, I; Labrador, M; Munoz-Bellido, F J; Pedraz, J; Serra-Baldrich, E et al.
DOI: 10.18176/jiaci.0661

COVID-19 vaccination-related adverse events among autoimmune disease patients: results from the COVAD study.

PMID: 35713499
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Dec 23;62(1):65-76. doi: 10.1093/rheumatology/keac305.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, Vikas; Agarwal, Vishwesh; Aggarwal, Rohit; Cavagna, Lorenzo; Chatterjee, Tulika; Chinoy, Hector; Day, Jessica; Distler, Oliver; Gheita, Tamer; Gracia-Ramos, Abraham Edgar et al.
DOI: 10.1093/rheumatology/keac305

Left ventricular diastolic dysfunction in systemic sclerosis: Clinical, immunological and survival differences in the Spanish RESCLE registry.

PMID: 35691226
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2022
Reference: Semin Arthritis Rheum. 2022 Aug;55:152033. doi: 10.1016/j.semarthrit.2022.152033. Epub 2022 May 28.
Impact factor:
Publication type: Paper in international publication
Authors: Argibay, Ana; Callejas Moraga, Eduardo; Chamorro, Antonio-J; Colunga Arguelles, Dolores; Fabregate, Martin; Fonollosa Pla, Vicent; Freire, Mayka; Gonzalez Garcia, Andres; Gonzalez-Echavarri, Cristina; Guillen Del Castillo, Alfredo et al.
DOI: 10.1016/j.semarthrit.2022.152033

Early outcomes in adults hospitalized with severe SARS-CoV-2 infection receiving tocilizumab.

PMID: 34544604
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin (Barc). 2022 Jun 10;158(11):509-518. doi: 10.1016/j.medcli.2021.06.012. Epub 2021 Jun 18.
Impact factor:
Publication type: Paper in national publication
Authors: Almirante, Benito; Anton, Andres; Augustin, Salvador; Bosch-Nicolau, Pau; Dura, Xavier; Eremiev-Eremiev, Simeon; Espinosa-Pereiro, Juan; Fernandez-Hidalgo, Nuria; Guillen-Del-Castillo, Alfredo; Miarons, Marta et al.
DOI: 10.1016/j.medcli.2021.06.012

Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air(R).

PMID: 34567526
Journal: Clinical and Translational Allergy
Year: 2021
Reference: Clin Transl Allergy. 2021 Sep 19;11(7):e12062. doi: 10.1002/clt2.12062. eCollection 2021 Aug.
Impact factor:
Publication type: Review in international publication
Authors: Anto, Josep M; Basagana, Xavier; Bedard, Annabelle; Bedbrook, Anna; Bindslev-Jensen, Carsten; Bosnic-Anticevich, Sinthia; Bousquet, Jean; Brussino, Luisa; Cardona, Victoria; Cruz, Alvaro A et al.
DOI: 10.1002/clt2.12062

Etiologies and 12-month mortality in patients with isolated involuntary weight loss at a rapid diagnostic unit.

PMID: 34555091
Journal: PLoS One
Year: 2021
Reference: PLoS One. 2021 Sep 23;16(9):e0257752. doi: 10.1371/journal.pone.0257752. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Abril, Andres; Aligue, Jordi; Arnau, Anna; Bonet, Mariona; El Boutrouki, Omar; Martinez, Eva; Ordeig, Josep; Ordeig, Roser; Ruiz, Domingo; San Jose, Antonio et al.
DOI: 10.1371/journal.pone.0257752

Galactosemia Diagnosis by Whole Exome Sequencing Later in Life.

PMID: 34514046
Journal: Movement Disorders Clinical Practice
Year: 2021
Reference: Mov Disord Clin Pract. 2021 Sep 3;8(Suppl 1):S37-S39. doi: 10.1002/mdc3.13295. eCollection 2021 Aug.
Impact factor:
Publication type: Letter or abstract
Authors: Camprodon-Gomez, Maria; Hernandez-Vara, Jorge; Lucas-Del-Pozo, Sara; Moreno-Martinez, Daniel; Moreno-Martinez, David et al.
DOI: 10.1002/mdc3.13295

Management of acquired hemophilia A: results from the Spanish Registry.

PMID: 34521101
Journal: Blood Advances
Year: 2021
Reference: Blood Adv. 2021 Oct 12;5(19):3821-3829. doi: 10.1182/bloodadvances.2021004626.
Impact factor:
Publication type: Paper in international publication
Authors: Aguinaco, Reyes; Alonso, Nieves; Alvarez-Roman, Maria-Teresa; Asenjo, Susana; Baena-Cubero, Angela; Bastida, Jose Maria; Caparros-Miranda, Isabel Socorro; Carrasco, Marina; Cervero-Santiago, Carlos; De La Puerta, Rosalia et al.
DOI: 10.1182/bloodadvances.2021004626

Tocilizumab in giant cell arteritis: differences between the GiACTA trial and a multicentre series of patients from the clinical practice.

PMID: 32441643
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2020
Reference: Clin Exp Rheumatol. 2020 Mar-Apr;38 Suppl 124(2):112-119. Epub 2020 May 21.
Impact factor:
Publication type: Paper in international publication
Authors: Aldasoro, Vicente; Alvarez Del Buergo, Maria; Alvarez-Rivas, Noelia; Arca, Beatriz; Atienza-Mateo, Belen; Aurrecoechea, Elena; Becerra-Fernandez, Elena; Blanco, Ricardo; Calderon-Goercke, Monica; Castaneda, Santos et al.
DOI:

Obstetrical outcome and treatments in seronegative primary APS: data from European retrospective study.

PMID: 32848089
Journal: RMD Open
Year: 2020
Reference: RMD Open. 2020 Aug;6(2):0. doi: 10.1136/rmdopen-2020-001340.
Impact factor:
Publication type: Paper in international publication
Authors: Abisror, Noemie; Alijotas-Reig, Jaume; Benedetto, Chiara; Benhamou, Ygal; Bezanahary, Holy; Billoir, Paul; Bornes, Marie; Bourrienne, Marie Charlotte; Carbillon, Lionel; De Moreuil, Claire et al.
DOI: 10.1136/rmdopen-2020-001340

Safety and effectiveness of a microcrystalline tyrosine-associated mite extract immunotherapy for allergic rhinitis.

PMID: 32811270
Journal: Immunotherapy
Year: 2020
Reference: Immunotherapy. 2020 Sep;12(13):1007-1019. doi: 10.2217/imt-2020-0194. Epub 2020 Aug 19.
Impact factor:
Publication type: Paper in international publication
Authors: Almeida-Sanchez, Zulay M; Alvarez-Fernandez, Jose A; Boronat-Barado, Anna; Garcia-Nunez, Ignacio; Justicia, Jose L; Linana-Santafe, Juan J; Martinez-Tadeo, Juan A; Perez-Formoso, Jose L; Sala-Cunill, Anna; Toran-Barona, Carla et al.
DOI: 10.2217/imt-2020-0194

Anti-HMGCR Specificity of HALIP: A Confirmatory Study.

PMID: 32766318
Journal: Journal of Immunology Research
Year: 2020
Reference: J Immunol Res. 2020 Jul 16;2020:6292631. doi: 10.1155/2020/6292631. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarado-Cardenas, Marcelo; Baucells, Andres; Juarez, Candido; Mariscal, Anais; Martinez, Maria Angeles; Martinez-Martinez, Laura; Selva-O'Callaghan, Albert et al.
DOI: 10.1155/2020/6292631

Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture.

PMID: 31557429
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2019
Reference: N Engl J Med. 2019 Dec 5;381(23):2199-2208. doi: 10.1056/NEJMoa1906190. Epub 2019 Sep 26.
Impact factor:
Publication type: Paper in international publication
Authors: ; Andres Peiro, José vicente; Barro Ojeda, Victor ; Bhandari, Mohit; Bzovsky, Sofia; Carbonell Rosell, Carla; Collado Gastalver, Diego; Devereaux, P J; Einhorn, Thomas A; Frihagen, Frede et al.
DOI: 10.1056/NEJMoa1906190

Urinary Neuropilin-1: A Predictive Biomarker for Renal Outcome in Lupus Nephritis.

PMID: 31533337
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2019
Reference: Int J Mol Sci. 2019 Sep 17;20(18). pii: ijms20184601. doi: 10.3390/ijms20184601.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Hotter, Georgina; Moline, Teresa; Ordi-Ros, Josep; Sanchis, Mireia; Sola, Anna; Sole, Cristina; Torres-Salido, Maria Teresa; Vidal, Marta; Vidal, Xavier et al.
DOI: 10.3390/ijms20184601

LAUDES Study: impact of digital ulcers on hand functional limitation, work productivity and daily activities, in systemic sclerosis patients.

PMID: 31522232
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2019
Reference: Rheumatol Int. 2019 Nov;39(11):1875-1882. doi: 10.1007/s00296-019-04436-z. Epub 2019 Sep 14.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Juan Jose; Aspe de la Iglesia, Bruno; Barbado Ajo, Julia; Batista Perdomo, Daniel; Beltran Catalan, Emma; Belzunegui Otano, Joaquin; Blanco Rodriguez, Jorge Santiago; Caamano Freire, Manuel; Callejas-Rubio, Jose Luis; Calvo-Alen, Jaime et al.
DOI: 10.1007/s00296-019-04436-z

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

PMID: 31516692
Journal: Clinical and Translational Allergy
Year: 2019
Reference: Clin Transl Allergy. 2019 Sep 9;9:44. doi: 10.1186/s13601-019-0279-2. eCollection 2019.
Impact factor:
Publication type: Review in international publication
Authors: Aberer, W; Agache, I; Agache, Ioana; Akdis, C A; Akdis, Cezmi A; Akdis, M; Aliberti, M R; Almeida, R; Amat, F; Angles, R et al.
DOI: 10.1186/s13601-019-0279-2

Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.

PMID: 30044938
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 Jul 26;379(4):352-362. doi: 10.1056/NEJMoa1716995.
Impact factor:
Publication type: Clinical Trials
Authors: Aberer, Werner; Aygoren-Pursun, Emel; Baeza, Maria L; Bygum, Anette; Cancian, Mauro; Cicardi, Marco; Clemons, Desiree; Collis, Phil; Cornpropst, Melanie; Dobo, Sylvia et al.
DOI: 10.1056/NEJMoa1716995

Management of asthma in the emergency department: a consensus statement.

PMID: 30033702
Journal: Emergencias
Year: 2018
Reference: Emergencias. 2018 Ago;30(4):268-277.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez Gutierrez, Francisco J; Alvarez Rodriguez, Cesareo; Delgado Romero, Julio; Dominguez Ortega, Javier; Labrador Horrillo, Moises; Martinez Moragon, Eva; Miguel Franco, Jose; Pinera Salmeron, Pascual; Plaza Moral, Vicente et al.
DOI:

Subclinical cardiovascular disease and Systemic Sclerosis: A comparison between risk charts, quantification of coronary calcium and carotid ultrasonography.

PMID: 30005858
Journal: AUTOIMMUNITY REVIEWS
Year: 2018
Reference: Autoimmun Rev. 2018 Sep;17(9):900-905. doi: 10.1016/j.autrev.2018.03.015. Epub 2018 Jul 11.
Impact factor:
Publication type: Review in national publication
Authors: Callejas Moragas, E; Cuellar Calabria, H; Fernandez Codina, A; Fonollosa Pla, V; Guillen Del Castillo, A; Martinez Valle, F; Orozco Galvez, O; Pizzi, M N; Roque Perez, A; Sanz Perez, I et al.
DOI: 10.1016/j.autrev.2018.03.015

Basic Skin Care and Topical Therapies for Atopic Dermatitis: Beyond Essential Approaches.

PMID: 30004024
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2018
Reference: J Investig Allergol Clin Immunol. 2018 Dec;28(6):379-391. doi: 10.18176/jiaci.0293. Epub 2018 Jul 13.
Impact factor:
Publication type: Editorail in international publication
Authors: Herraez, L; Lazaro, M; Moro-Moro, M; Quinones, M D; Sala-Cunill, A; Sanchez, I et al.
DOI: 10.18176/jiaci.0293

Influence of antibody profile in clinical features and prognosis in a cohort of Spanish patients with systemic sclerosis.

PMID: 28980912
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2017
Reference: Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):98-105. Epub 2017 Sep 21.
Impact factor:
Publication type: Paper in international publication
Authors: Chamorro Fernandez, Antonio Javier; Colunga Arguelles, Dolores; Egurbide Arberas, Maria Victoria; Espinosa, Gerard; Fonollosa Pla, Vicent; Freire, Mayka; Garcia Hernandez, Francisco Jose; Guillen Del Castillo, Alfredo; Iniesta Arandia, Nerea; Madronero Vuelta, Ana Belen et al.
DOI:

Clinical and epidemiological differences between men and women with systemic sclerosis: a study in a Spanish systemic sclerosis cohort and literature review.

PMID: 28980905
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2017
Reference: Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):89-97. Epub 2017 Sep 18.
Impact factor:
Publication type: Review in international publication
Authors: Callejas Rubio, Jose Luis; Colunga Arguelles, Dolores; Egurbide Arberas, Maria Victoria; Fonollosa Pla, Vicent; Freire, Mayka; Garcia Hernandez, Francisco Jose; Guillen-Del Castillo, Alfredo; Iniesta Arandia, Nerea; Madronero Vuelta, Ana Belen; Marin Ballve, Adela et al.
DOI:

Positive prayer sign in eosinophilic fasciitis.

PMID: 28934835
Journal: RHEUMATOLOGY
Year: 2017
Reference: Rheumatology (Oxford). 2017 Apr 1;56(4):628. doi: 10.1093/rheumatology/kew415.
Impact factor:
Publication type: Paper in international publication
Authors: Pardos-Gea, Jose et al.
DOI: 10.1093/rheumatology/kew415

Corrigendum to "Increasing Dose of Autologous Bone Marrow Mononuclear Cells Transplantation Is Related to Stroke Outcome: Results from a Pooled Analysis of Two Clinical Trials".

PMID: 28883838
Journal: Stem Cells International
Year: 2017
Reference: Stem Cells Int. 2017;2017:7946930. doi: 10.1155/2017/7946930. Epub 2017 Aug 13.
Impact factor:
Publication type: Letter or abstract
Authors: Bustamante, Alejandro; Cabezas, Juan Antonio; Carmona, Magdalena; de Freitas, Gabriel R; de la Torre Laviana, Francisco Javier; Escudero, Irene; Gonzalez, Alejandro; Lebrato, Lucia; Mendez-Otero, Rosalia; Moniche, Francisco et al.
DOI: 10.1155/2017/7946930

Effect of coenzyme Q plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise testing in chronic fatigue syndrome - A randomized, controlled, double-blind trial.

PMID: 26212172
Journal: CLINICAL NUTRITION
Year: 2016
Reference: Clin Nutr. 2016 Aug;35(4):826-34. doi: 10.1016/j.clnu.2015.07.010. Epub 2015 Jul 17.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Aliste, Luisa; Calvo, Natalia; Castro-Marrero, Jesus; Faro, Monica; Fernandez de Sevilla, Tomas; Saez-Francas, Naia; Segundo, Maria Jose et al.
DOI: 10.1016/j.clnu.2015.07.010

Gastrointestinal endarteropathy in adult dermatomyositis.

PMID: 26184526
Journal: JOINT BONE SPINE
Year: 2016
Reference: Joint Bone Spine. 2016 May;83(3):353-4. doi: 10.1016/j.jbspin.2015.03.004. Epub 2015 Jul 14.
Impact factor:
Publication type: Paper in international publication
Authors: Landolfi, Stefania; Mestre-Torres, Jaume; Selva-O'Callaghan, Albert et al.
DOI: 10.1016/j.jbspin.2015.03.004

Anti-MDA5 dermatomyositis and progressive interstitial pneumonia.

PMID: 25784769
Journal: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Year: 2016
Reference: QJM. 2016 Jan;109(1):49-50. doi: 10.1093/qjmed/hcv068. Epub 2015 Mar 16.
Impact factor:
Publication type: Paper in international publication
Authors: Arredondo-Agudelo, K V; Bravo-Masgoret, C; Labrador-Horrillo, M; Ramos-Terrades, N; Selva-O'Callaghan, A; Silveira, M G et al.
DOI: 10.1093/qjmed/hcv068

Sequence analysis of TMEM173 exon 5 in patients with systemic autoimmune diseases.

PMID: 26593864
Journal: AUTOIMMUNITY
Year: 2016
Reference: Autoimmunity. 2016;49(1):12-6. doi: 10.3109/08916934.2015.1113404. Epub 2015 Nov 22.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, E; Felip, L; Ordi-Ros, J; Selva-O'Callaghan, A; Simeon-Aznar, C P; Solans-Laque, R; Vilardell-Tarres, M et al.
DOI: 10.3109/08916934.2015.1113404

How are we treating our systemic patients with primary Sjogren syndrome? Analysis of 1120 patients.

PMID: 25899085
Journal: INT IMMUNOPHARMACOL
Year: 2015
Reference: Int Immunopharmacol. 2015 Aug;27(2):194-9. doi: 10.1016/j.intimp.2015.03.027. Epub 2015 Apr 18.
Impact factor:
Publication type: Paper in international publication
Authors: Adrianov, B; Akasbi, M; Akasbi, M; Ayala, M M; Bosch, J A; Bosch, J A; Bove, A; Brito-Zeron, P; Brito-Zeron, P; Callejas, J L et al.
DOI: 10.1016/j.intimp.2015.03.027

Geriatric Screening Tools to Select Older Adults Susceptible for Direct Transfer From the Emergency Department to Subacute Intermediate-Care Hospitalization.

PMID: 26027719
Journal: J AM MED DIR ASSOC
Year: 2015
Reference: J Am Med Dir Assoc. 2015 Oct 1;16(10):837-41. doi: 10.1016/j.jamda.2015.04.009. Epub 2015 May 29.
Impact factor:
Publication type: Paper in international publication
Authors: Colprim, Daniel; Gual, Neus; Inzitari, Marco; Jimenez, Xavier; Perez-Bocanegra, Carmen; Roig, Thais; San-Jose, Antonio et al.
DOI: 10.1016/j.jamda.2015.04.009

Validation of EULAR primary Sjogren's syndrome disease activity (ESSDAI) and patient indexes (ESSPRI).

PMID: 24442883
Journal: ANN RHEUM DIS
Year: 2015
Reference: Ann Rheum Dis. 2015 May;74(5):859-66. doi: 10.1136/annrheumdis-2013-204615. Epub 2014 Jan 17.
Impact factor:
Publication type: Paper in international publication
Authors: Bartoloni, Elena; Bartoloni, Elena; Bicetre, Kremlin; Bombardieri, Stefano; Bombardieri, Stefano; Bootsma, Hendrika; Bootsma, Hendrika; Bowman, Netherlands Simon J; Bowman, Simon J; Brun, Johan G et al.
DOI: 10.1136/annrheumdis-2013-204615

[Renopulmonary syndrome, importance of an early diagnosis].

PMID: 25088654
Journal: MED CLIN-BARCELONA
Year: 2015
Reference: Med Clin (Barc). 2015 May 8;144(9):430-1. doi: 10.1016/j.medcli.2014.06.002. Epub 2014 Aug 1.
Impact factor:
Publication type: Letter or abstract
Authors: Martinez-Valle, Ferran; Mestre-Torres, Jaume; Salcedo-Allende, M Teresa; Solans Laque, Roser et al.
DOI: 10.1016/j.medcli.2014.06.002

Outcomes of off-label drug uses in hospitals: a multicentric prospective study.

PMID: 25196202
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2014
Reference: Eur J Clin Pharmacol. 2014 Nov;70(11):1385-93. doi: 10.1007/s00228-014-1746-2. Epub 2014 Sep 9.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, A; Alerany, C; Bonafont, X; Bosch, J A; Danes, I; Ferrer, A; Gratacos, L; Marron, S M Cano; Martinez, J; Olmo, M et al.
DOI: 10.1007/s00228-014-1746-2

Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing.

PMID: 25179678
Journal: European Journal of Internal Medicine
Year: 2014
Reference: Eur J Intern Med. 2014 Oct;25(8):710-6. doi: 10.1016/j.ejim.2014.07.011. Epub 2014 Aug 29.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, Antonia; Barbe, Jose; Fernandez-Moyano, Antonio; Formiga, Francesc; Garcia, Juana; Lopez-Soto, Alfonso; Ramirez-Duque, Nieves; San-Jose, Antonio; Torres, Olga H; Vidal, Xavier et al.
DOI: 10.1016/j.ejim.2014.07.011

Clinical and serological findings associated with the expression of ITGAL, PRF1, and CD70 in systemic lupus erythematosus.

PMID: 24238281
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2014
Reference: Clin Exp Rheumatol. 2014 Jan-Feb;32(1):113-6. Epub 2013 Nov 15.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, Eva; Castro-Marrero, Jesus; Felip, Lledo; Ordi-Ros, Josep; Vilardell-Tarres, Miquel et al.
DOI:

Correlation of ultrasound B-lines with high-resolution computed tomography in antisynthetase syndrome.

PMID: 24773767
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2014
Reference: Clin Exp Rheumatol. 2014 May-Jun;32(3):404-7. Epub 2014 Apr 28.
Impact factor:
Publication type: Clinical Trials
Authors: Castella-Fierro, E; Martinez-Gomez, X; Pallisa Nunez, E; Pinal Fernandez, I; Selva-O'Callaghan, A; Vilardell-Tarres, Miquel et al.
DOI:

[Procalcitonine as a biomarker in patients with systemic lupus erythematosus.]

PMID: 23276619
Journal: MEDICINA CLINICA
Year: 2013
Reference: Med Clin (Barc). 2013 Mar 2;140(5):214-6. doi: 10.1016/j.medcli.2012.10.009. Epub 2012 Dec 29.
Impact factor:
Publication type: Editorial in national publication
Authors: Consiglio, Francisco Javier; Ordi Ros, Josep et al.
DOI: 10.1016/j.medcli.2012.10.009

Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review.

PMID: 23122952
Journal: FERTILITY AND STERILITY
Year: 2013
Reference: Fertil Steril. 2013 Feb;99(2):441-9. doi: 10.1016/j.fertnstert.2012.10.009. Epub 2012 Nov 2.
Impact factor:
Publication type: Review in international publication
Authors: Alijotas-Reig, Jaume; Llurba, Elisa; Palacio-Garcia, Carles; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.fertnstert.2012.10.009

Inflammatory, immune-mediated adverse reactions related to soft tissue dermal fillers.

PMID: 23642806
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2013
Reference: Semin Arthritis Rheum. 2013 Oct;43(2):241-58. doi: 10.1016/j.semarthrit.2013.02.001. Epub 2013 May 2.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume; Fernandez-Figueras, Maria Teresa; Puig, Lluis et al.
DOI: 10.1016/j.semarthrit.2013.02.001

Idiopathic retroperitoneal fibrosis: a clinicopathological study in 24 Spanish cases.

PMID: 23515600
Journal: CLINICAL RHEUMATOLOGY
Year: 2013
Reference: Clin Rheumatol. 2013 Jun;32(6):889-93. doi: 10.1007/s10067-013-2225-3. Epub 2013 Mar 21.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus; Detorres, Ines; Fernandez-Codina, Andreu; Martinez-Valle, Fernando; Ordi-Ros, Jose; Vilardell-Tarres, Miquel et al.
DOI: 10.1007/s10067-013-2225-3

[Erdheim-Chester disease: study of 12 cases.]

PMID: 22795496
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Oct 13;139(9):398-403. doi: 10.1016/j.medcli.2012.05.001. Epub 2012 Jul 12.
Impact factor:
Publication type: Editorial in national publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.medcli.2012.05.001

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.

PMID: 22076442
Journal: HUMAN MOLECULAR GENETICS
Year: 2012
Reference: Hum Mol Genet. 2012 Feb 15;21(4):926-33. Epub 2011 Nov 10.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, Sandeep K; Aguirre, Ma Angeles; Airo, Paolo; Andreu, Jose Luis; Arnett, Frank C; Assassi, Shervin; Beltran, Emma; Beretta, Lorenzo; Bossini-Castillo, Lara; Broen, Jasper et al.
DOI: 10.1093/hmg/ddr522

[New trends in the treatment of amyloidosis.]

PMID: 22197598
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 May 26;138(15):667-72. Epub 2011 Dec 22.
Impact factor:
Publication type: Review in national publication
Authors: ; ; et al.
DOI: 10.1016/j.medcli.2011.09.032

Registry of the Spanish Network for Systemic Sclerosis: Clinical Pattern According to Cutaneous Subsets and Immunological Status.

PMID: 22169458
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2012
Reference: Semin Arthritis Rheum. 2012 Jun;41(6):789-800. Epub 2011 Dec 12.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.semarthrit.2011.10.004

Development of a questionnaire to assess patient satisfaction with allergen-specific immunotherapy in adults: item generation, item reduction, and preliminary validation.

PMID: 21660106
Journal: Patient Preference and Adherence
Year: 2011
Reference: Patient Prefer Adherence. 2011;5:239-50. Epub 2011 May 24.
Impact factor:
Publication type: Letter or abstract
Authors: Baro, Eva; Cardona, Victoria; Guardia, Pedro; Justicia, Jose Luis; Ojeda, Pedro; Olaguibel, Jose Maria; Vega, Jose Maria; Vidal, Carmen et al.
DOI: 10.2147/PPA.S19219

Bosentan in Clinical Practice for Treating Digital and Other Ischemic Ulcers in Spanish Patients with Systemic Sclerosis: IBER-DU Cohort Study.

PMID: 21632679
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2011
Reference: J Rheumatol. 2011 Aug;38(8):1631-5. Epub 2011 Jun 1.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.3899/jrheum.101266

Effectiveness of Combined Pharmacologic and Ligation Therapy in High-Risk Patients With Acute Esophageal Variceal Bleeding.

PMID: 21625271
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2011
Reference: Am J Gastroenterol. 2011 Oct;106(10):1787-95. doi: 10.1038/ajg.2011.173. Epub 2011 May 31.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/ajg.2011.173

[Clinical features and prognosis of patients with scleroderma renal crisis.]

PMID: 21596402
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Oct 15;137(10):431-4. Epub 2011 May 18.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; ; et al.
DOI: 10.1016/j.medcli.2011.03.014

World Allergy Organization survey on global availability of essentials for the assessment and management of anaphylaxis by allergy-immunology specialists in health care settings.

PMID: 20486330
Journal: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Year: 2010
Reference: Ann Allergy Asthma Immunol. 2010 May;104(5):405-12.
Impact factor:
Publication type: Paper in international publication
Authors: Betschel, Stephen; Bilo, Beatrice; Bisyuk, Yuriy; Cardona, Victoria; Chng, Hiok Hee; Dahl, Ronald; deGroot, Hans; Djuric, Vojislav; Dumitrascu, Diana; Durham, Stephen et al.
DOI:

Development of a self-reporting tool to obtain a combined index of severity of fibromyalgia (ICAF).

PMID: 20055985
Journal: Health and Quality of Life Outcomes
Year: 2010
Reference: Health Qual Life Outcomes. 2010 Jan 7;8(1):2.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, C; Alperi, M; Ballina, F J; Belenguer, R; Belmonte, M; Beltran, J; Blanch, J; Collado, A; Esteve-Vives, Joaquim; Fernandez-Dapica, P et al.
DOI: 10.1186/1477-7525-8-2

Transcriptome profile in Williams-Beuren syndrome lymphoblast cells reveals gene pathways implicated in glucose intolerance and visuospatial construction deficits.

PMID: 20401492
Journal: HUMAN GENETICS
Year: 2010
Reference: Hum Genet. 2010 Jul;128(1):27-37. doi: 10.1007/s00439-010-0817-4. Epub 2010 Apr 17.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; et al.
DOI: 10.1007/s00439-010-0817-4

Letter: vasculitis related to non-animal hyaluronic acid skin filler injection.

PMID: 20402961
Journal: DERMATOLOGIC SURGERY
Year: 2010
Reference: Dermatol Surg. 2010 Feb;36(2):272-3.
Impact factor:
Publication type: Letter or abstract
Authors: Alijotas Reig, Jaume; Alijotas-Reig, Jaume et al.
DOI: 10.1111/j.1524-4725.2009.01416.x

Metabotyping of biofluids reveals stress-based differences in gut permeability in healthy individuals.

PMID: 19736998
Journal: JOURNAL OF PROTEOME RESEARCH
Year: 2009
Reference: J Proteome Res. 2009 Oct;8(10):4799-809.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Carmen; Guilarte, Mar; Kochhar, Sunil; Lobo, Beatriz; Malagelada, Juan Ramon; Martin, Francois-Pierre; Martinez, Cristina; Ramos, Laura; Rezzi, Serge; Santos, Javier et al.
DOI: 10.1021/pr900525w

Epstein-Barr virus-associated lymphoma in patients with dermatomyositis. Be aware of double immunosuppression.

PMID: 19696063
Journal: RHEUMATOLOGY
Year: 2009
Reference: Rheumatology (Oxford). 2009 Nov;48(11):1462-3.
Impact factor:
Publication type: Letter or abstract
Authors: Labirua, Anne; Palacios, Andres; Salcedo-Allende, Teresa; Selva-O'Callaghan, Albert; Solans-Laque, Roser; Vilardell-Tarres, Miquel et al.
DOI: 10.1093/rheumatology/kep247

Predicting Early Mortality After Acute Variceal Hemorrhage Based on Classification and Regression Tree Analysis.

PMID: 19699816
Journal: Clinical Gastroenterology and Hepatology
Year: 2009
Reference: Clin Gastroenterol Hepatol. 2009 Dec;7(12):1347-54.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.cgh.2009.08.011

Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity.

PMID: 19714703
Journal: REVIEWS IN MEDICAL VIROLOGY
Year: 2009
Reference: Rev Med Virol. 2009 Sep;19(5):273-86.
Impact factor:
Publication type: Review in international publication
Authors: Balada, Eva; Ordi-Ros, Josep; Vilardell-Tarres, Miquel et al.
DOI: 10.1002/rmv.622

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News

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.