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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Team

Neus Prades Gimeno

Neus Prades Gimeno

Research assistant
Systemic Diseases
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Olga Luengo Sanchez

Olga Luengo Sanchez

Systemic Diseases
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Roser Solans Laque

Roser Solans Laque

Systemic Diseases
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Segundo Bujan Rivas

Segundo Bujan Rivas

Systemic Diseases
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Neus Prades Gimeno

Neus Prades Gimeno

Research assistant
Systemic Diseases
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Olga Luengo Sanchez

Olga Luengo Sanchez

Systemic Diseases
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Roser Solans Laque

Roser Solans Laque

Systemic Diseases
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Segundo Bujan Rivas

Segundo Bujan Rivas

Systemic Diseases
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Research lines

MYOGEN study. Genome Wide Association study in myositis.

We are currently enrolled in this worldwide study to detect global genetic alterations in patients with myositis. Twenty centres from Europe and United States participate in this study. We contribute to add the genetic information of the patients from our population. Professor Frederick W. Miller (Bethesda, USA) and Dr. Ingrid Lundberg (Stockholm, Sweden) lead the project.

IP: Albert Selva O'Callaghan

Paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria is a under diagnosed disease due to its low prevalence and the fact that occasionally debuts as an atypical form. Thrombosis of atypical localization, moreover associated to anemia of unknown origin requires screening for HPN.

IP: José Pardos Gea

Pathogenic role of cellular microparticles and anti-phospholipid/anti-cofactor antibodies in recurrent implantation failures related to In Vitro Fertilization (IVF).

The prevalence of failed IVF is high or very high. Besides problems intrinsic to the technique, we know almost nothing about the possible underlying causes. Anti-phospholipid/anti-cofactor (aPL/aCF) antibodies have been associated to several obstetric complications. Nevertheless, the role that these aPL/aCF antibodies may have in failed IVF is not well defined. With this randomized study we want to understand better the use that these antibodies may have on a clinical daily basis. Along with the microparticles analysis, we could end up by finding several elements that might act as risk markers; in turn, it might even help us to fine-tune the currently used therapeutic approaches.

IP: Jaume Alijotas Reig

Predictive kit to detect the possible establishment of late adverse effects related to bioimplants used in clinical practice.

A high variability in the prevalence of adverse effects with an immunologic basis seems to be related with any implant used in clinical practice. We have managed to find a particular association of HLA haplotypes that increase the risk for developing these effects up to 600 times. We are nowadays working on setting up a safe and reliable biochip or kit which predicts this risk easily in a routine test.

IP: Jaume Alijotas Reig

Publications

Hormonal control during infancy and testicular adrenal rest tumor development in CAH males - a retrospective multi-center cohort study.

PMID: 37837609
Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY
Year: 2023
Reference: Eur J Endocrinol. 2023 Oct 14:lvad143. doi: 10.1093/ejendo/lvad143.
Impact factor:
Publication type: Paper in international publication
Authors: Adriaansen, Bas P H; Ahmed, S Faisal; Ali, Salma R; Amr, Nermine Hussein; Bachega, Tania A S S; Baronio, Federico; Birkebaek, Niels Holtum; Bonfig, Walter; Bryce, Jillian; Cardona, Victoria et al.
DOI: 10.1093/ejendo/lvad143

ESMO Guidance for Reporting Oncology real-World evidence (GROW).

PMID: 37848160
Journal: ANNALS OF ONCOLOGY
Year: 2023
Reference: Ann Oncol. 2023 Oct 10:S0923-7534(23)04018-8. doi: 10.1016/j.annonc.2023.10.001.
Impact factor:
Publication type: Paper in international publication
Authors: Almonacid Sanchez, C; Alvarez Gutierrez, F J; Banas Conejero, D; Bliss, J; Booth, C M; Cardona, V; Castelo-Branco, L; Dafni, U; Delaloge, S; Dellaporta, T et al.
DOI: 10.1016/j.annonc.2023.10.001

Influence of forearm rotation on the kinetic stabilizing efficiency of the muscles that control the scapholunate joint. Clinical application in proprioceptive and neuromuscular rehabilitation programs.

PMID: 37852910
Journal: Journal of Hand Therapy
Year: 2023
Reference: J Hand Ther. 2023 Oct 17:S0894-1130(23)00137-0. doi: 10.1016/j.jht.2023.09.012.
Impact factor:
Publication type: Paper in international publication
Authors: Cruz, M J; Espejo, D; Esplugas, Mireia; Fernandez-Noguera, Nuria; Garcia-Elias, Marc; Gomez-Domingo, M R; Lluch, Alex; Llusa-Perez, Manuel; Luengo, O; Munoz, X et al.
DOI: 10.1016/j.jht.2023.09.012

Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen.

PMID: 37915062
Journal: CRITICAL CARE
Year: 2023
Reference: Crit Care. 2023 Nov 1;27(1):419. doi: 10.1186/s13054-023-04687-0.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin-Amerigo, D; Artigas, Antoni; Asensio Sanchez, M T; Blot, Pierre-Louis; Cartailler, Jerome; Chousterman, Benjamin G; Corrales Vargas, S I; Garcia-de-Acilu, Marina; Jauregui Presa, I; Joral Badas, A et al.
DOI: 10.1186/s13054-023-04687-0

Is humoral and cellular response to SARS-CoV-2 vaccine modified by DMT in patients with multiple sclerosis and other autoimmune diseases?

PMID: 35475363
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27.
Impact factor: 6.312
Publication type: Paper in international publication
Authors: Arrambide, Georgina, Otero-Romero, Susana, Pappolla, Agustin, Tagliani, Paula, Lopez-Maza, Samuel, Cardenas-Robledo, Simon, Esperalba, Juliana, Fernandez-Naval, Candela, Martinez-Gallo, Monica, Castillo, Mireia et al.
DOI: 10.1177/13524585221089540

Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency.

PMID: 35464398
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Apr 8;13:881206. doi: 10.3389/fimmu.2022.881206. eCollection 2022.
Impact factor: 7.561
Publication type: Paper in international publication
Authors: Labrador-Horrillo, Moises, Franco-Jarava, Clara, Parra-Martinez, Alba, Antolin, Maria, Salgado-Perandres, Sandra, Aguilo-Cucurull, Aina, Martinez-Gallo, Monica, Colobran, Roger, Garcia-Prat, Marina et al.
DOI: 10.3389/fimmu.2022.881206

Anti-FHL1 antibody: welcome to a novel autoantibody in myositis.

PMID: 35460231
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Apr 23. pii: 6572805. doi: 10.1093/rheumatology/keac252.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Selva-O'Callaghan, Albert, Trallero-Araguas, Ernesto, Sanz-Martinez, Maria Teresa et al.
DOI: 10.1093/rheumatology/keac252

Antiphospholipid antibodies in women with recurrent embryo implantation failure: A systematic review and meta-analysis.

PMID: 35452853
Journal: AUTOIMMUNITY REVIEWS
Year: 2022
Reference: Autoimmun Rev. 2022 Jun;21(6):103101. doi: 10.1016/j.autrev.2022.103101. Epub 2022 Apr 20.
Impact factor: 9.754
Publication type: Review in international publication
Authors: Jarne-Borras, Marina, Miro-Mur, Francesc, Anunciacion-Llunell, Ariadna, Alijotas-Reig, Jaume et al.
DOI: 10.1016/j.autrev.2022.103101

Complement Component C1q as a Potential Diagnostic Tool for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Subtyping.

PMID: 34575280
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Sep 15;10(18). pii: jcm10184171. doi: 10.3390/jcm10184171.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Zacares, Mario, Almenar-Perez, Eloy, Alegre-Martin, Jose, Oltra, Elisa et al.
DOI: 10.3390/jcm10184171

Integration of in vitro allergy test results and ratio analysis for the diagnosis and treatment of allergic patients (INTEGRA).

PMID: 34582103
Journal: Clinical and Translational Allergy
Year: 2021
Reference: Clin Transl Allergy. 2021 Aug;11(7):e12052. doi: 10.1002/clt2.12052.
Impact factor: 5.871
Publication type: Review in international publication
Authors: Pascal, Mariona, Moreno, Carmen, Davila, Ignacio, Tabar, Ana I, Labrador, Moises, Luengo, Olga, Bartra, Joan et al.
DOI: 10.1002/clt2.12052

Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air(R).

PMID: 34567526
Journal: Clinical and Translational Allergy
Year: 2021
Reference: Clin Transl Allergy. 2021 Sep 19;11(7):e12062. doi: 10.1002/clt2.12062. eCollection 2021 Aug.
Impact factor: 5.871
Publication type: Review in international publication
Authors: Brussino, Luisa, Cardona, Victoria, Cruz, Alvaro A, de Vries, Govert, Devillier, Philippe, Fokkens, Wytske J, Fuentes-Perez, Jose Miguel, Gemicioglu, Bilun, Haahtela, Tari, Huerta-Villalobos, Yunen Rocio et al.
DOI: 10.1002/clt2.12062

Effect of Dietary Coenzyme Q10 Plus NADH Supplementation on Fatigue Perception and Health-Related Quality of Life in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.

PMID: 34444817
Journal: Nutrients
Year: 2021
Reference: Nutrients. 2021 Jul 30;13(8). pii: nu13082658. doi: 10.3390/nu13082658.
Impact factor: 5.719
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Segundo, Maria Jose, Lacasa, Marcos, Martinez-Martinez, Alba, Sentanes, Ramon Sanmartin, Alegre-Martin, Jose et al.
DOI: 10.3390/nu13082658

Antihistamine-resistant chronic spontaneous urticaria remains undertreated: 2-year data from the AWARE study.

PMID: 32735720
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2020
Reference: Clin Exp Allergy. 2020 Oct;50(10):1166-1175. doi: 10.1111/cea.13716. Epub 2020 Sep 3.
Impact factor: 4.217
Publication type: Paper in international publication
Authors: Chapman-Rothe, N, Maurer, M, Costa, C, Gimenez Arnau, A, Guillet, G, Labrador-Horrillo, M, Lapeere, H, Meshkova, R, Savic, S et al.
DOI: 10.1111/cea.13716

Analysis of the correlation between disease activity score 28 and its ultrasonographic equivalent in rheumatoid arthritis patients.

PMID: 32716834
Journal: European journal of rheumatology
Year: 2020
Reference: Eur J Rheumatol. 2020 Jul 21. pii: eurjrheum.2020.20038. doi: 10.5152/eurjrheum.2020.20038.
Impact factor: 0
Publication type: Paper in international publication
Authors: Coras, Roxana, Sturchio, Gustavo Anez, Bru, Mireia Barcelo, Fernandez, Agusti Sellas, Farietta, Sandra, Badia, Salvador Campos, Diez, Basilio Rodriguez, de Agustin de Oro, Juan Jose et al.
DOI: 10.5152/eurjrheum.2020.20038

Efficacy of Thalidomide in Discoid Lupus Erythematosus: Insights into the Molecular Mechanisms.

PMID: 32659758
Journal: DERMATOLOGY
Year: 2020
Reference: Dermatology. 2020;236(5):467-476. doi: 10.1159/000508672. Epub 2020 Jul 13.
Impact factor: 3.695
Publication type: Review in international publication
Authors: Domingo, Sandra, Sole, Cristina, Moline, Teresa, Ferrer, Berta, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al.
DOI: 10.1159/000508672

Application of specific-to-total IgE ratio does not benefit diagnostic performance of serologic testing for rocuronium allergy.

PMID: 32620258
Journal: BRITISH JOURNAL OF ANAESTHESIA
Year: 2020
Reference: Br J Anaesth. 2020 Dec;125(6):e443-e446. doi: 10.1016/j.bja.2020.05.032. Epub 2020 Jun 30.
Impact factor: 6.88
Publication type: Letter or abstract
Authors: Molina-Molina, Gustavo, Van Gasse, Athina L, Hagendorens, Margo M, Faber, Margaretha A, De Puysseleyr, Leander, Elst, Jessy, Mertens, Christel M, Horiuchi, Tatsuo, Sabato, Vito, Ebo, Didier G et al.
DOI: 10.1016/j.bja.2020.05.032

Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial.

PMID: 31610549
Journal: ANNALS OF INTERNAL MEDICINE
Year: 2019
Reference: Ann Intern Med. 2019 Nov 19;171(10):685-694. doi: 10.7326/M19-0291. Epub 2019 Oct 15.
Impact factor: 19.315
Publication type: Paper in international publication
Authors: Cuquet-Pedragosa, Jordi, Ortiz-Santamaria, Vera, Mauri-Plana, Montserrat, Sole, Cristina, Cortes-Hernandez, Josefina, Castro-Salomo, Antoni, Riera-Mestre, Antoni, Vidal, Xavier, Perez-Conesa, Mercedes, Ordi-Ros, Josep et al.
DOI: 10.7326/M19-0291

Functional rare variants influence the clinical response to anti-TNF therapy in Crohn's disease.

PMID: 31598133
Journal: Therapeutic Advances in Gastroenterology
Year: 2019
Reference: Therap Adv Gastroenterol. 2019 Sep 25;12:1756284819867848. doi: 10.1177/1756284819867848. eCollection 2019.
Impact factor: 3.961
Publication type: Paper in international publication
Authors: Olivares, David, Aguilar-Melero, Patricia, Menchen, Luis, Ferreiro-Iglesias, Rocio, Blazquez Gomez, Isabel, Benitez Garcia, Beatriz, Guijarro, Luis G, Marin, Alicia C, Bernardo, David, Marsal, Sara et al.
DOI: 10.1177/1756284819867848

Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis.

PMID: 30621746
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2019
Reference: Arthritis Res Ther. 2019 Jan 8;21(1):11. doi: 10.1186/s13075-018-1772-z.
Impact factor: 4.148
Publication type: Paper in international publication
Authors: Rodriguez-Lozano, Carlos, Linares, Luis Francisco, Urruticoechea, Ana, Collantes, Eduardo, Morla, Rosa Maria, Reina, Delia, Cuende, Eduardo, Zarco, Pedro, Fernandez-Espartero, Maria Cruz, Garcia-Vicuna, Rosario et al.
DOI: 10.1186/s13075-018-1772-z

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1).

PMID: 31559071
Journal: Journal of Thoracic Disease
Year: 2019
Reference: J Thorac Dis. 2019 Aug;11(8):3633-3642. doi: 10.21037/jtd.2019.08.64.
Impact factor: 2.027
Publication type: Paper in international publication
Authors: Tsiligianni, Ioanna, Bousquet, Jean, Pham-Thi, Nhan, Bedbrook, Anna, Agache, Ioana, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep M, Bachert, Claus, Benveniste, Samuel et al.
DOI: 10.21037/jtd.2019.08.64

Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.

PMID: 30044938
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 Jul 26;379(4):352-362. doi: 10.1056/NEJMoa1716995.
Impact factor: 79.258
Publication type: Clinical Trials
Authors: Aygoren-Pursun, Emel, Bygum, Anette, Grivcheva-Panovska, Vesna, Magerl, Markus, Graff, Jochen, Maurer, Marcus, Cicardi, Marco, Sheridan, William, Collis, Phil, Fang, Lei et al.
DOI: 10.1056/NEJMoa1716995

Phenotypes, endotypes and biomarkers in anaphylaxis: current insights.

PMID: 30048251
Journal: Current Opinion in Allergy and Clinical Immunology
Year: 2018
Reference: Curr Opin Allergy Clin Immunol. 2018 Oct;18(5):370-376. doi: 10.1097/ACI.0000000000000472.
Impact factor: 3.544
Publication type: Review in international publication
Authors: Sala-Cunill, Anna, Guilarte, Mar, Cardona, Victoria et al.
DOI: 10.1097/ACI.0000000000000472

Management of asthma in the emergency department: a consensus statement.

PMID: 30033702
Journal: Emergencias
Year: 2018
Reference: Emergencias. 2018 Ago;30(4):268-277.
Impact factor: 3.608
Publication type: Paper in international publication
Authors: Pinera Salmeron, Pascual, Delgado Romero, Julio, Dominguez Ortega, Javier, Labrador Horrillo, Moises, Alvarez Gutierrez, Francisco J, Martinez Moragon, Eva, Plaza Moral, Vicente, Alvarez Rodriguez, Cesareo, Miguel Franco, Jose et al.
DOI:

Subclinical cardiovascular disease and Systemic Sclerosis: A comparison between risk charts, quantification of coronary calcium and carotid ultrasonography.

PMID: 30005858
Journal: AUTOIMMUNITY REVIEWS
Year: 2018
Reference: Autoimmun Rev. 2018 Sep;17(9):900-905. doi: 10.1016/j.autrev.2018.03.015. Epub 2018 Jul 11.
Impact factor: 8.745
Publication type: Review in national publication
Authors: Sanz Perez, I, Martinez Valle, F, Guillen Del Castillo, A, Roque Perez, A, Cuellar Calabria, H, Pizzi, M N, Fernandez Codina, A, Callejas Moragas, E, Orozco Galvez, O, Fonollosa Pla, V et al.
DOI: 10.1016/j.autrev.2018.03.015

CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report.

PMID: 29075437
Journal: Clinical and Translational Allergy
Year: 2017
Reference: Clin Transl Allergy. 2017 Oct 23;7:37. doi: 10.1186/s13601-017-0173-8. eCollection 2017.
Impact factor: 3.239
Publication type: Review in national publication
Authors: Valero, A, Ivancevich, J C, Larenas-Linnemann, D, Millot-Keurinck, J, Ryan, D, Samolinski, B, Sheikh, A, Yorgancioglu, A, Agache, I, Arnavielhe, S et al.
DOI: 10.1186/s13601-017-0173-8

Downregulation of mucosal mast cell activation and immune response in diarrhoea-irritable bowel syndrome by oral disodium cromoglycate: A pilot study.

PMID: 29026603
Journal: United European Gastroenterology Journal
Year: 2017
Reference: United European Gastroenterol J. 2017 Oct;5(6):887-897. doi: 10.1177/2050640617691690. Epub 2017 Jan 29.
Impact factor: 3.673
Publication type: Paper in international publication
Authors: Azpiroz, Fernando, Santos, Javier, Vicario, Maria, Guagnozzi, Danila, Pardo-Camacho, Cristina, Salvo-Romero, Eloisa, Lobo, Beatriz, Ramos, Laura, Martinez, Cristina, Guilarte, Mar et al.
DOI: 10.1177/2050640617691690

Genetic variation associated with cardiovascular risk in autoimmune diseases.

PMID: 28982122
Journal: PLoS One
Year: 2017
Reference: PLoS One. 2017 Oct 5;12(10):e0185889. doi: 10.1371/journal.pone.0185889. eCollection 2017.
Impact factor: 2.806
Publication type: Paper in international publication
Authors: Aterido, Adria, Fernandez-Nebro, Antonio, Canete, Juan D, Ferrandiz, Carlos, Tornero, Jesus, Gisbert, Javier P, Domenech, Eugeni, Fernandez-Gutierrez, Benjamin, Gomollon, Fernando, Garcia-Planella, Esther et al.
DOI: 10.1371/journal.pone.0185889

Influence of antibody profile in clinical features and prognosis in a cohort of Spanish patients with systemic sclerosis.

PMID: 28980912
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2017
Reference: Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):98-105. Epub 2017 Sep 21.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Iniesta Arandia, Nerea, Simeon-Aznar, Carmen Pilar, Guillen Del Castillo, Alfredo, Colunga Arguelles, Dolores, Rubio-Rivas, Manuel, Trapiella Martinez, Luis, Garcia Hernandez, Francisco Jose, Saez Comet, Luis, Egurbide Arberas, Maria Victoria, Ortego-Centeno, Norberto et al.
DOI:

Gastrointestinal endarteropathy in adult dermatomyositis.

PMID: 26184526
Journal: JOINT BONE SPINE
Year: 2016
Reference: Joint Bone Spine. 2016 May;83(3):353-4. doi: 10.1016/j.jbspin.2015.03.004. Epub 2015 Jul 14.
Impact factor: 2.901
Publication type: Paper in international publication
Authors: Mestre-Torres, Jaume, Landolfi, Stefania, Selva-O'Callaghan, Albert et al.
DOI: 10.1016/j.jbspin.2015.03.004

Anti-MDA5 dermatomyositis and progressive interstitial pneumonia.

PMID: 25784769
Journal: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Year: 2016
Reference: QJM. 2016 Jan;109(1):49-50. doi: 10.1093/qjmed/hcv068. Epub 2015 Mar 16.
Impact factor: 2.495
Publication type: Paper in international publication
Authors: Silveira, M G, Selva-O'Callaghan, A, Ramos-Terrades, N, Arredondo-Agudelo, K V, Labrador-Horrillo, M, Bravo-Masgoret, C et al.
DOI: 10.1093/qjmed/hcv068

Fast 1.5 T chest MRI for the assessment of interstitial lung disease extent secondary to systemic sclerosis.

PMID: 27107755
Journal: CLINICAL RHEUMATOLOGY
Year: 2016
Reference: Clin Rheumatol. 2016 Sep;35(9):2339-45. doi: 10.1007/s10067-016-3267-0. Epub 2016 Apr 23.
Impact factor: 2.042
Publication type: Paper in international publication
Authors: Pinal-Fernandez, Iago, Pineda-Sanchez, Victor, Pallisa-Nunez, Esther, Simeon-Aznar, Carmen Pilar, Selva-O'Callaghan, Albert, Fonollosa-Pla, Vicente, Vilardell-Tarres, Miquel et al.
DOI: 10.1007/s10067-016-3267-0

Sequence analysis of TMEM173 exon 5 in patients with systemic autoimmune diseases.

PMID: 26593864
Journal: AUTOIMMUNITY
Year: 2016
Reference: Autoimmunity. 2016;49(1):12-6. doi: 10.3109/08916934.2015.1113404. Epub 2015 Nov 22.
Impact factor: 2.917
Publication type: Paper in international publication
Authors: Balada, E, Selva-O'Callaghan, A, Felip, L, Ordi-Ros, J, Simeon-Aznar, C P, Solans-Laque, R, Vilardell-Tarres, M et al.
DOI: 10.3109/08916934.2015.1113404

Geriatric Screening Tools to Select Older Adults Susceptible for Direct Transfer From the Emergency Department to Subacute Intermediate-Care Hospitalization.

PMID: 26027719
Journal: Journal of the American Medical Directors Association
Year: 2015
Reference: J Am Med Dir Assoc. 2015 Oct 1;16(10):837-41. doi: 10.1016/j.jamda.2015.04.009. Epub 2015 May 29.
Impact factor: 4.939
Publication type: Paper in international publication
Authors: Inzitari, Marco, Colprim, Daniel, Perez-Bocanegra, Carmen, San-Jose, Antonio, Jimenez, Xavier, Roig, Thais, Gual, Neus et al.
DOI: 10.1016/j.jamda.2015.04.009

Association of CCR5Delta32 and Behcet's disease: new data from a case-control study in the Spanish population and meta-analysis.

PMID: 26393284
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2015
Reference: Clin Exp Rheumatol. 2015 Nov-Dec;33(6 Suppl 94):S96-100. Epub 2015 Sep 22.
Impact factor: 2.724
Publication type: Review in national publication
Authors: Martin, Javier, Ortiz-Fernandez, Lourdes, Garcia-Lozano, Jose-Raul, Montes-Cano, Marco-Antonio, Conde-Jaldon, Marta, Ortego-Centeno, Norberto, Castillo-Palma, Maria-Jesus, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan et al.
DOI:

[Anemia in elderly patients admitted to an acute geriatric ward].

PMID: 25749584
Journal: Revista espanola de geriatria y gerontologia
Year: 2015
Reference: Rev Esp Geriatr Gerontol. 2015 May-Jun;50(3):122-5. doi: 10.1016/j.regg.2014.09.002. Epub 2015 Mar 4.
Impact factor: 0
Publication type: Paper in national publication
Authors: San Jose-Laporte, Antonio, Barbe-Gil Ortega, Jose, Duran-Taberna, Montserrat, Romero-Ruperto, Sheila, Perez-Bocanegra, Maria Carmen, Toscano-Rivera, Ainhoa et al.
DOI: 10.1016/j.regg.2014.09.002

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.

PMID: 25817017
Journal: AMERICAN JOURNAL OF HUMAN GENETICS
Year: 2015
Reference: Am J Hum Genet. 2015 Apr 2;96(4):565-80. doi: 10.1016/j.ajhg.2015.02.009. Epub 2015 Mar 26.
Impact factor: 10.931
Publication type: Paper in international publication
Authors: Martin, Javier, Carmona, F David, Mackie, Sarah L, Martin, Jose-Ezequiel, Taylor, John C, Vaglio, Augusto, Eyre, Stephen, Bossini-Castillo, Lara, Castaneda, Santos, Cid, Maria C et al.
DOI: 10.1016/j.ajhg.2015.02.009

The phenotype of TNF receptor-associated autoinflammatory syndrome (TRAPS) at presentation: a series of 158 cases from the Eurofever/EUROTRAPS international registry.

PMID: 23965844
Journal: ANN RHEUM DIS
Year: 2014
Reference: Ann Rheum Dis. 2014 Dec;73(12):2160-7. doi: 10.1136/annrheumdis-2013-204184. Epub 2013 Aug 21.
Impact factor: 9.111
Publication type: Paper in international publication
Authors: Obici, L, Lachmann, H J, Papa, R, Gerhold, K, Frenkel, J, Anton, J, Kone-Paut, I, Cattalini, M, Bader-Meunier, B, Insalaco, A et al.
DOI: 10.1136/annrheumdis-2013-204184

Interlaboratory reproducibility and proficiency testing within the human papillomavirus cervical cancer screening program in Catalonia, Spain.

PMID: 24574284
Journal: J CLIN MICROBIOL
Year: 2014
Reference: J Clin Microbiol. 2014 May;52(5):1511-8. doi: 10.1128/JCM.00100-14. Epub 2014 Feb 26.
Impact factor: 4.232
Publication type: Paper in international publication
Authors: Bravo, I G, Ordi, J, Ibanez, R, Felez-Sanchez, M, Godinez, J M, Guardia, C, Caballero, E, Juve, R, Combalia, N, Bellosillo, B et al.
DOI: 10.1128/JCM.00100-14

A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA.

PMID: 25409453
Journal: PLOS ONE
Year: 2014
Reference: PLoS One. 2014 Nov 19;9(11):e113476. doi: 10.1371/journal.pone.0113476. eCollection 2014.
Impact factor: 3.534
Publication type: Paper in international publication
Authors: Marquez, Ana, Solans, Roser, Hernandez-Rodriguez, Jose, Cid, Maria C, Castaneda, Santos, Ramentol, Marc, Rodriguez-Rodriguez, Luis, Narvaez, Javier, Blanco, Ricardo, Ortego-Centeno, Norberto et al.
DOI: 10.1371/journal.pone.0113476

GIMAP and Behcet disease: no association in the European population.

PMID: 24625627
Journal: ANN RHEUM DIS
Year: 2014
Reference: Ann Rheum Dis. 2014 Jul;73(7):1433-4. doi: 10.1136/annrheumdis-2013-205156. Epub 2014 Mar 13.
Impact factor: 9.27
Publication type: Letter or abstract
Authors: Ortiz-Fernandez, Lourdes, Conde-Jaldon, Marta, Garcia-Lozano, Jose Raul, Montes-Cano, Marco Antonio, Ortego-Centeno, Norberto, Castillo-Palma, Maria Jesus, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Gonzalez-Gay, Miguel Angel et al.
DOI: 10.1136/annrheumdis-2013-205156

Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier.

PMID: 22637702
Journal: GUT
Year: 2013
Reference: Gut. 2013 Aug;62(8):1160-8. doi: 10.1136/gutjnl-2012-302093. Epub 2012 May 25.
Impact factor: 10.732
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/gutjnl-2012-302093

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.

PMID: 23372721
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013;8(1):e54419. doi: 10.1371/journal.pone.0054419. Epub 2013 Jan 23.
Impact factor: 3.73
Publication type: Paper in international publication
Authors: Vonk, Madelon C, Fernandez-Castro, Monica, Saez-Comet, Luis, Beltran, Emma, Camps, Maria Teresa, Egurbide, Maria Victoria, Airo, Paolo, Scorza, Raffaella, Lunardi, Claudio, Hunzelmann, Nicolas et al.
DOI: 10.1371/journal.pone.0054419

The role of neuroticism, perfectionism and depression in chronic fatigue syndrome. A structural equation modeling approach.

PMID: 23759150
Journal: COMPREHENSIVE PSYCHIATRY
Year: 2013
Reference: Compr Psychiatry. 2013 Oct;54(7):1061-7. doi: 10.1016/j.comppsych.2013.04.015. Epub 2013 Jun 5.
Impact factor: 2.376
Publication type: Paper in international publication
Authors: Valero, Sergi, Saez-Francas, Naia, Calvo, Natalia, Alegre, Jose, Casas, Miquel et al.
DOI: 10.1016/j.comppsych.2013.04.015

Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity.

PMID: 23249956
Journal: EUROPEAN JOURNAL OF HUMAN GENETICS
Year: 2013
Reference: Eur J Hum Genet. 2013 Jun;21(6):659-65. doi: 10.1038/ejhg.2012.229. Epub 2012 Dec 19.
Impact factor: 4.319
Publication type: Paper in international publication
Authors: Glavac, Damjan, Gut, Ivo, Klovins, Janis, Krawczak, Michael, Kucinskas, Vaidutis, Lathrop, Mark, Macek, Milan, Marsal, Sara, Meitinger, Thomas, Melegh, Bela et al.
DOI: 10.1038/ejhg.2012.229

[Erdheim-Chester disease: study of 12 cases.]

PMID: 22795496
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Oct 13;139(9):398-403. doi: 10.1016/j.medcli.2012.05.001. Epub 2012 Jul 12.
Impact factor: 1.385
Publication type: Editorial in national publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.medcli.2012.05.001

A 79-year-old man with dyspnea, Dysphagia, and weakness.

PMID: 22796848
Journal: CHEST
Year: 2012
Reference: Chest. 2012 Jul 1;142(1):252-5.
Impact factor: 5.25
Publication type: Paper in international publication
Authors: Riveiro-Barciela, Mar, Labirua-Iturburu, Ane, Selva-O'Callaghan, Albert et al.
DOI: 10.1378/chest.11-2437

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.

PMID: 22076442
Journal: HUMAN MOLECULAR GENETICS
Year: 2012
Reference: Hum Mol Genet. 2012 Feb 15;21(4):926-33. Epub 2011 Nov 10.
Impact factor: 7.636
Publication type: Paper in international publication
Authors: Vaqueiro, Ines, Bossini-Castillo, Lara, Martin, Jose-Ezequiel, Broen, Jasper, Gorlova, Olga, Simeon, Carmen P, Beretta, Lorenzo, Vonk, Madelon C, Callejas, Jose Luis, Castellvi, Ivan et al.
DOI: 10.1093/hmg/ddr522

[New trends in the treatment of amyloidosis.]

PMID: 22197598
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 May 26;138(15):667-72. Epub 2011 Dec 22.
Impact factor: 1.385
Publication type: Review in national publication
Authors: , , et al.
DOI: 10.1016/j.medcli.2011.09.032

Development of a questionnaire to assess patient satisfaction with allergen-specific immunotherapy in adults: item generation, item reduction, and preliminary validation.

PMID: 21660106
Journal: Patient Preference and Adherence
Year: 2011
Reference: Patient Prefer Adherence. 2011;5:239-50. Epub 2011 May 24.
Impact factor:
Publication type: Letter or abstract
Authors: Justicia, Jose Luis, Baro, Eva, Cardona, Victoria, Guardia, Pedro, Ojeda, Pedro, Olaguibel, Jose Maria, Vega, Jose Maria, Vidal, Carmen et al.
DOI: 10.2147/PPA.S19219

Bosentan in Clinical Practice for Treating Digital and Other Ischemic Ulcers in Spanish Patients with Systemic Sclerosis: IBER-DU Cohort Study.

PMID: 21632679
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2011
Reference: J Rheumatol. 2011 Aug;38(8):1631-5. Epub 2011 Jun 1.
Impact factor: 3.551
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.3899/jrheum.101266

[Clinical features and prognosis of patients with scleroderma renal crisis.]

PMID: 21596402
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Oct 15;137(10):431-4. Epub 2011 May 18.
Impact factor: 1.413
Publication type: Paper in national publication
Authors: , , , , et al.
DOI: 10.1016/j.medcli.2011.03.014

Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis.

PMID: 21571730
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2011
Reference: Ann Rheum Dis. 2011 Nov;70(11):2050-2. Epub 2011 May 13.
Impact factor: 9.082
Publication type: Letter or abstract
Authors: , , , , , , , , , et al.
DOI: 10.1136/ard.2010.148874

Off-label use of rituximab in 196 patients with severe, refractory systemic autoimmune diseases.

PMID: 20525449
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2010
Reference: Clin Exp Rheumatol. 2010 Jul-Aug;28(4):468-76. Epub 2010 Aug 30.
Impact factor: 2.396
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI:

[Common variable immunodeficiency. Prognostic factors for lung damage]

PMID: 19811791
Journal: MEDICINA CLINICA
Year: 2010
Reference: Med Clin (Barc). 2010 Jan 30;134(2):64-7. Epub 2009 Oct 6.
Impact factor: 1.231
Publication type: Paper in national publication
Authors: Sala Cunill, Anna, Soler-Palacin, Pere, Martin De Vicente, Carlos, Labrador Horrillo, Moises, Luengo Sanchez, Olga, Figueras Nadal, Concepcio et al.
DOI: 10.1016/j.medcli.2009.06.050

Anti-beta(2)-glycoprotein-I and anti-phosphatidylserine antibodies in women with spontaneous pregnancy loss.

PMID: 19296946
Journal: FERTILITY AND STERILITY
Year: 2010
Reference: Fertil Steril. 2010 May 1;93(7):2330-6.
Impact factor: 3.97
Publication type: Paper in international publication
Authors: Alijotas Reig, Jaume, Vilardell-Tarres, Miquel, Cabero-Roura, Luis, Farran-Codina, Immaculada, Rodrigo-Anoro, Maria Jose, Alijotas-Reig, Jaume, Ferrer-Oliveras, Raquel et al.
DOI: 10.1016/j.fertnstert.2009.01.089

World Allergy Organization survey on global availability of essentials for the assessment and management of anaphylaxis by allergy-immunology specialists in health care settings.

PMID: 20486330
Journal: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Year: 2010
Reference: Ann Allergy Asthma Immunol. 2010 May;104(5):405-12.
Impact factor: 2.457
Publication type: Paper in international publication
Authors: El-Gamal, Yehia, Gaspar, Angela, Gonzalez-Diaz, Sandra, Hanna, Kamal, Hassan, Rashidul, Jia, Yin, Kalayci, Omer, Kaulsay, Ranbir, Khaitov, Rakhim, Kontou-Fili, Kalliopi et al.
DOI:

[Serotonin syndrome associated with linezolid]

PMID: 19211077
Journal: MEDICINA CLINICA
Year: 2009
Reference: Med Clin (Barc). 2009 Feb 7;132(4):157-8.
Impact factor: 1.258
Publication type: Letter or abstract
Authors: Hernandez-Lorente, Eva, Broto, Pilar Lalueza, Simeon Aznar, Carmen P, Brumos, Lourdes Girona et al.
DOI: 10.1016/j.medcli.2008.09.007

Obstructive sleep apnea in patients with inflammatory myopathies.

PMID: 19145652
Journal: MUSCLE & NERVE
Year: 2009
Reference: Muscle Nerve. 2009 Feb;39(2):144-9.
Impact factor: 2.594
Publication type: Paper in international publication
Authors: Sampol, Gabriel, Romero, Odile, Lloberes, Patricia, Trallero-Araguas, Ernesto, Vilardell-Tarres, Miquel, Selva-O'Callaghan, Albert et al.
DOI: 10.1002/mus.21204

NOD2-associated pediatric granulomatous arthritis, an expanding phenotype: study of an international registry and a national cohort in Spain.

PMID: 19479837
Journal: ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
Year: 2009
Reference: Arthritis Rheum. 2009 Jun;60(6):1797-803.
Impact factor: 6.787
Publication type: Paper in international publication
Authors: Rose, Carlos D, Arostegui, Juan I, Martin, Tammy M, Espada, Graciela, Scalzi, Lisabeth, Yague, Jordi, Rosenbaum, James T, Modesto, Consuelo, Cristina Arnal, Maria, Merino, Rosa et al.
DOI: 10.1002/art.24533

[Raynaud's phenomenon]

PMID: 19268319
Journal: MEDICINA CLINICA
Year: 2009
Reference: Med Clin (Barc). 2009 May 16;132(18):712-8.
Impact factor: 1.258
Publication type: Paper in national publication
Authors: Tolosa Vilella, Carles, Simeon Aznar, Carmen Pilar, Gabarro Julia, Lourdes et al.
DOI: 10.1016/j.medcli.2008.11.017

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