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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Research lines

Serological markers study in anaphylaxis.

We are performing a follow up study of different serological markers in patients who have suffered some anaphylactic episodes. The main goal consists on detecting anaphylaxis patients at the intensive care unit and to determine different serological and plasma markers, mainly tryptase and carboxypeptidase levels by means of a sandwich ELISA.

IP: Moisés Labrador Horrillo

Significance of Capillaroscopy in Raynaud's phenomenon and scleroderma.

We want to describe the capillaroscopy alterations observed in patients with Raynaud's phenomenon and scleroderma. Our main objective is to establish the different patterns that may be related to visceral involvement and to the prognosis in the early stages of the disease.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Spanish Registry of patients with Behçet disease (REGEB).

This is a multicentre study supported by the Systemic Autoimmune Diseases Group from the Spanish Internal Medicine Society. The aim of the study is to describe the different clinical forms of disease presentation in our country and the response of the disease to conventional treatment.

IP: Roser Solans Laque

Spanish Registry of patients with primary Sjögren’s syndrome.

This is a multicentre study supported by the Systemic Autoimmune Diseases Group (GEAS) from the Spanish Internal Medicine Society (SEMI). Its main goal consist in investigate the factors involved in extraglandular development in our country. This study is coordinated by Dr. Manel Ramos  from the Clinic Hospital, Barcelona.

IP: Roser Solans Laque

Publications

Incidence, predictors, and prognostic significance of impaired functional status early after transcatheter aortic valve replacement.

PMID: 38000627
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2023
Reference: Rev Esp Cardiol (Engl Ed). 2023 Nov 22:S1885-5857(23)00310-9. doi: 10.1016/j.rec.2023.11.003.
Impact factor:
Publication type: Paper in international publication
Authors: Abisror, Noemie; Alijotas-Reig, Jaume; Asmarats, Luis; Avvedimento, Marisa; Belahnech, Yassin; Bonnet, Guillaume; Cheema, Asim N; Cheloufi, Meryam; Coulomb, Aurore; De La Torre Hernandez, Jose M et al.
DOI: 10.1016/j.rec.2023.11.003

Sustained response off-treatment in eltrombopag-treated adult patients with ITP who are refractory or relapsed after first-line steroids: Primary, final, and ad-hoc analyses of the Phase II TAPER trial.

PMID: 38014779
Journal: AMERICAN JOURNAL OF HEMATOLOGY
Year: 2023
Reference: Am J Hematol. 2023 Nov 28. doi: 10.1002/ajh.27131.
Impact factor:
Publication type: Paper in international publication
Authors: Aguinaco, Reyes; Astigarraga, Itziar; Bastida, Jose Maria; Bernardo, Angel; Carrasco, Marina; Clark, Joan; Closa, Laia; Cooper, Nichola; Corrales, Irene; Ferrero, Ainara et al.
DOI: 10.1002/ajh.27131

A projected cost-utility analysis of avacopan for the treatment of antineutrophil cytoplasmic antibody-associated vasculitis in Spain.

PMID: 38126738
Journal: Expert Review of Pharmacoeconomics & Outcomes Research
Year: 2023
Reference: Expert Rev Pharmacoecon Outcomes Res. 2023 Dec 21. doi: 10.1080/14737167.2023.2297790.
Impact factor:
Publication type: Paper in international publication
Authors: Castells, Alejandra Garcia; de Arellano, Antonio Ramirez; Diaz-Encarnacion, Montserrat; Escribano, Cristina; Macia, Manuel; Mallol, Elisenda Pomares; Solans-Laque, Roser et al.
DOI: 10.1080/14737167.2023.2297790

Thrombosis recurrence and major bleeding in non-anticoagulated thrombotic antiphospholipid syndrome patients: Prospective study from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) clinical database and repository ("Registry").

PMID: 38185079
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2023
Reference: Semin Arthritis Rheum. 2023 Dec 20;65:152347. doi: 10.1016/j.semarthrit.2023.152347.
Impact factor:
Publication type: Paper in international publication
Authors: Artim-Esen, Bahar; Atsumi, Tatsuya; Barber, Megan R W; Belmont, H Michael; Bertolaccini, Maria Laura; Branch, D Ware; Cervera, Ricard; Cheildze, Dachi; Clarke, Ann; Cohen, Hannah et al.
DOI: 10.1016/j.semarthrit.2023.152347

Characterization and outcomes of 414 patients with primary SS who developed hematological malignancies.

PMID: 35385104
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Apr 6. pii: 6564238. doi: 10.1093/rheumatology/keac205.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Takagi, Y, Retamozo, Soledad, Kvarnstrom, Marika, Sebastian, Agata, Atzeni, Fabiola, Giacomelli, Roberto, Carsons, Steven E, Kwok, Seung-Ki, Nakamura, Hideki, Fernandes Moca Trevisani, Virginia et al.
DOI: 10.1093/rheumatology/keac205

Recovery of serum testosterone levels is an accurate predictor of survival from COVID-19 in male patients.

PMID: 35351135
Journal: BMC Medicine
Year: 2022
Reference: BMC Med. 2022 Mar 29;20(1):129. doi: 10.1186/s12916-022-02345-w.
Impact factor: 8.775
Publication type: Paper in international publication
Authors: Gallo, Monica Martinez, Arrese-Munoz, Iria, Gine, Anna, Diaz-Troyano, Noelia, Gabriel-Medina, Pablo, Riveiro-Barciela, Mar, Labrador-Horrillo, Moises, Martinez-Valle, Fernando, Montalva, Adrian Sanchez, Hernandez-Gonzalez, Manuel et al.
DOI: 10.1186/s12916-022-02345-w

The added value of a European Reference Network on rare and complex connective tissue and musculoskeletal diseases: insights after the first 5 years of the ERN ReCONNET.

PMID: 35349419
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2022
Reference: Clin Exp Rheumatol. 2022 May;40 Suppl 134(5):3-11. doi: 10.55563/clinexprheumatol/d2qz38. Epub 2022 Mar 29.
Impact factor: 4.473
Publication type: Review in international publication
Authors: Cornet, Alain, Talarico, Rosaria, Aguilera, Silvia, Alexander, Tobias, Amoura, Zahir, Andersen, Janette, Arnaud, Laurent, Avcin, Tadej, Marsal Barril, Sara, Beretta, Lorenzo et al.
DOI:

Allergen immunotherapy in MASK-air users in real-life: Results of a Bayesian mixed-effects model.

PMID: 35344295
Journal: Clinical and Translational Allergy
Year: 2022
Reference: Clin Transl Allergy. 2022 Mar;12(3):e12128. doi: 10.1002/clt2.12128.
Impact factor: 5.871
Publication type: Paper in international publication
Authors: Klimek, Ludger, Sousa-Pinto, Bernardo, Azevedo, Luis Filipe, Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Kuna, Piotr, Kaidashev, Igor, Kraxner, Helga, Larenas-Linnemann, Desiree E et al.
DOI: 10.1002/clt2.12128

Milestones of Precision Medicine: An Innovative, Multidisciplinary Overview.

PMID: 34331269
Journal: Molecular Diagnosis & Therapy
Year: 2021
Reference: Mol Diagn Ther. 2021 Sep;25(5):563-576. doi: 10.1007/s40291-021-00544-4. Epub 2021 Jul 30.
Impact factor: 4.074
Publication type: Review in international publication
Authors: Garcia-Foncillas, Jesus, Argente, Jesus, Bujanda, Luis, Cardona, Victoria, Casanova, Bonaventura, Fernandez-Montes, Ana, Horcajadas, Jose A, Iniguez, Andres, Ortiz, Alberto, Pablos, Jose L et al.
DOI: 10.1007/s40291-021-00544-4

Anaphylaxis Induced By Beer.

PMID: 32938573
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Investig Allergol Clin Immunol. 2021 Jul 26;31(4):334-336. doi: 10.18176/jiaci.0643. Epub 2020 Sep 15.
Impact factor: 7.033
Publication type: Paper in international publication
Authors: Labrador-Horrillo, M, Roger, A, Basagana, M, Pineda, F, Lazo, C, Navarro, L et al.
DOI: 10.18176/jiaci.0643

PAGE Study: Summary of a study protocol to estimate the prevalence of severe asthma in Spain using big-data methods.

PMID: 31983679
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Investig Allergol Clin Immunol. 2021 Jul 26;31(4):308-315. doi: 10.18176/jiaci.0483. Epub 2020 Jan 23.
Impact factor: 7.033
Publication type: Paper in international publication
Authors: Almonacid Sanchez, C, Melero Moreno, C, Quirce Gancedo, S, Sanchez-Herrero, M G, Alvarez Gutierrez, F J, Banas Conejero, D, Cardona, V, Soriano, J B et al.
DOI: 10.18176/jiaci.0483

Clinical characteristics of COVID-19 in older adults. A retrospective study in long-term nursing homes in Catalonia.

PMID: 34297774
Journal: PLoS One
Year: 2021
Reference: PLoS One. 2021 Jul 23;16(7):e0255141. doi: 10.1371/journal.pone.0255141. eCollection 2021.
Impact factor: 3.24
Publication type: Paper in international publication
Authors: Garcia-Navarro, Jose Augusto, San-Jose, Antonio, Andreu, Antoni L, Campins, Magda, Almirante, Benito, Santaeugenia, Sebastia, Ussi, Anton, Lopez-Segui, Francesc, Meis-Pinheiro, Uxio, Walsh, Sandra et al.
DOI: 10.1371/journal.pone.0255141

Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis.

PMID: 32546599
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2020
Reference: Ann Rheum Dis. 2020 Sep;79(9):1234-1242. doi: 10.1136/annrheumdis-2019-216599. Epub 2020 Jun 16.
Impact factor: 16.102
Publication type: Paper in international publication
Authors: Miller, Frederick W, Milisenda, Jose Cesar, Grau-Junyent, Josep Maria, Selva-O'Callaghan, Albert, Carrion-Ribas, Carme, Paik, Julie J, Albayda, Jemima, Christopher-Stine, Lisa, Lloyd, Thomas E, Corse, Andrea M et al.
DOI: 10.1136/annrheumdis-2019-216599

Recommendations for the treatment of anti-melanoma differentiation-associated gene 5-positive dermatomyositis-associated rapidly progressive interstitial lung disease.

PMID: 32534273
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2020
Reference: Semin Arthritis Rheum. 2020 Aug;50(4):776-790. doi: 10.1016/j.semarthrit.2020.03.007. Epub 2020 Jun 1.
Impact factor: 4.751
Publication type: Paper in international publication
Authors: Selva-O'Callaghan, A, Romero-Bueno, F, Diaz Del Campo, P, Trallero-Araguas, E, Ruiz-Rodriguez, J C, Castellvi, I, Rodriguez-Nieto, M J, Martinez-Becerra, M J, Sanchez-Pernaute, O, Pinal-Fernandez, I et al.
DOI: 10.1016/j.semarthrit.2020.03.007

Tigecycline-associated hypofibrinogenemia in a real-world setting.

PMID: 32504166
Journal: International Journal of Clinical Pharmacy
Year: 2020
Reference: Int J Clin Pharm. 2020 Aug;42(4):1184-1189. doi: 10.1007/s11096-020-01072-7. Epub 2020 Jun 5.
Impact factor: 1.616
Publication type: Paper in international publication
Authors: Campany-Herrero, David, Larrosa-Garcia, Maria, Lalueza-Broto, Pilar, Rivera-Sanchez, Lucas, Espinosa-Pereiro, Juan, Mestre-Torres, Jaume, Pigrau-Serrallach, Carles et al.
DOI: 10.1007/s11096-020-01072-7

Is diet partly responsible for differences in COVID-19 death rates between and within countries?

PMID: 32499909
Journal: Clinical and Translational Allergy
Year: 2020
Reference: Clin Transl Allergy. 2020 May 27;10:16. doi: 10.1186/s13601-020-00323-0. eCollection 2020.
Impact factor: 5.129
Publication type: Review in international publication
Authors: Laune, Daniel, Bousquet, Jean, Anto, Josep M, Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi A, Blain, Hubert, Canonica, G Walter et al.
DOI: 10.1186/s13601-020-00323-0

LAUDES Study: impact of digital ulcers on hand functional limitation, work productivity and daily activities, in systemic sclerosis patients.

PMID: 31522232
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2019
Reference: Rheumatol Int. 2019 Nov;39(11):1875-1882. doi: 10.1007/s00296-019-04436-z. Epub 2019 Sep 14.
Impact factor: 2.2
Publication type: Paper in international publication
Authors: Castellvi, Ivan, Eguiluz, Saioa, Escudero-Contreras, Alejandro, Rios, Juan Jose, Calvo-Alen, Jaime, Callejas-Rubio, Jose Luis, De la Puente, Carlos, Simeon, Carmen Pilar, Narvaez, Francisco Javier, Espinosa, Gerard et al.
DOI: 10.1007/s00296-019-04436-z

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

PMID: 31516692
Journal: Clinical and Translational Allergy
Year: 2019
Reference: Clin Transl Allergy. 2019 Sep 9;9:44. doi: 10.1186/s13601-019-0279-2. eCollection 2019.
Impact factor: 4.232
Publication type: Review in international publication
Authors: Dokic, Dejand, Fonseca, Joao A, Gaga, Mina, Haahtela, Tari, Illario, Maddalena, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L T T, Larenas-Linnemann, Desiree et al.
DOI: 10.1186/s13601-019-0279-2

Biosimilar and interchangeable: Inseparable scientific concepts?

PMID: 31486117
Journal: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2019
Reference: Br J Clin Pharmacol. 2019 Nov;85(11):2460-2463. doi: 10.1111/bcp.14089. Epub 2019 Sep 4.
Impact factor: 3.867
Publication type: Paper in international publication
Authors: de Mora, Fernando, Balsa, Alejandro, Cornide-Santos, Maria, Carrascosa, Jose-Manuel, Marsal, Sara, P Gisbert, Javier, Abad, Miguel-Angel, F Duarte, Rafael, Wiechmann, Michael, Martinez, Rafael et al.
DOI: 10.1111/bcp.14089

Systemic manifestations of primary Sjogren's syndrome out of the ESSDAI classification: prevalence and clinical relevance in a large international, multi-ethnic cohort of patients.

PMID: 31464664
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2019
Reference: Clin Exp Rheumatol. 2019 May-Jun;37 Suppl 118(3):97-106. Epub 2019 Aug 28.
Impact factor: 3.238
Publication type: Paper in international publication
Authors: Danda, Debashish, Praprotnik, Sonja, Kvarnstrom, Marika, Gerli, Roberto, Sebastian, Agata, Solans, Roser, Rischmueller, Maureen, Pasoto, Sandra G, Valim, Valeria, Nordmark, Gunnel et al.
DOI:

Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis.

PMID: 29874259
Journal: PLoS One
Year: 2018
Reference: PLoS One. 2018 Jun 6;13(6):e0198106. doi: 10.1371/journal.pone.0198106. eCollection 2018.
Impact factor: 2.766
Publication type: Paper in international publication
Authors: Cambras, Trinitat, Castro-Marrero, Jesus, Zaragoza, Maria Cleofe, Diez-Noguera, Antoni, Alegre, Jose et al.
DOI: 10.1371/journal.pone.0198106

Cancer-associated Dermatomyositis: Does the PD-1 Checkpoint Pathway Play a Role?

PMID: 29858454
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2018
Reference: J Rheumatol. 2018 Jun;45(6):731-732. doi: 10.3899/jrheum.180007.
Impact factor: 3.47
Publication type: Editorail in international publication
Authors: Labrador-Horrillo, Moises, Selva-O'Callaghan, Albert et al.
DOI: 10.3899/jrheum.180007

Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.

PMID: 29848360
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2018
Reference: Arthritis Res Ther. 2018 May 30;20(1):100. doi: 10.1186/s13075-018-1604-1.
Impact factor: 4.269
Publication type: Paper in international publication
Authors: de la Fuente, Jose Luis Marenco, Zea, Antonio, Pego-Reigosa, Jose Maria, Freire, Mercedes, Diez, Elvira, Rodriguez-Almaraz, Esther, Carreira, Patricia, Blanco, Ricardo, Taboada, Victor Martinez, Lopez-Lasanta, Maria et al.
DOI: 10.1186/s13075-018-1604-1

Efficacy of Idursulfase therapy in patients with Mucopolysaccharidosis type II who initiated enzyme replacement therapy in adult age. A systematic review of the literature.

PMID: 29801985
Journal: MOLECULAR GENETICS AND METABOLISM
Year: 2018
Reference: Mol Genet Metab. 2018 Jul;124(3):216-227. doi: 10.1016/j.ymgme.2018.04.013. Epub 2018 Apr 30.
Impact factor: 3.774
Publication type: Paper in international publication
Authors: Del Toro, M, Ceberio-Hualde, L, Munoz-Delgado, C, Perez-Lopez, J, Molto-Abad, M, Morales-Conejo, M et al.
DOI: 10.1016/j.ymgme.2018.04.013

Mutational profile of rare variants in inflammasome-related genes in Behcet disease: A Next Generation Sequencing approach.

PMID: 28814775
Journal: Scientific Reports
Year: 2017
Reference: Sci Rep. 2017 Aug 16;7(1):8453. doi: 10.1038/s41598-017-09164-7.
Impact factor: 4.259
Publication type: Paper in international publication
Authors: Castaneda, Santos, Alegre-Sancho, Juan-Jose, Martin, Javier, Gonzalez-Escribano, Maria Francisca, Camps, Teresa, Rodriguez-Rodriguez, Luis, Rodriguez-Carballeira, Monica, Fanlo, Patricia, Burillo-Sanz, Sergio, Montes-Cano, Marco-Antonio et al.
DOI: 10.1038/s41598-017-09164-7

Safety of Adrenaline Use in Anaphylaxis: A Multicentre Register.

PMID: 28793302
Journal: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Year: 2017
Reference: Int Arch Allergy Immunol. 2017;173(3):171-177. doi: 10.1159/000477566. Epub 2017 Aug 9.
Impact factor: 2.72
Publication type: Paper in international publication
Authors: Cardona, Victoria, Ferre-Ybarz, Laia, Guilarte, Mar, Moreno-Perez, Nuria, Gomez-Galan, Catalina, Alcoceba-Borras, Eva, Delavalle, Maria Belen, Garriga-Baraut, Teresa et al.
DOI: 10.1159/000477566

The Mast Cell, Contact, and Coagulation System Connection in Anaphylaxis.

PMID: 28798744
Journal: Frontiers in Immunology
Year: 2017
Reference: Front Immunol. 2017 Jul 26;8:846. doi: 10.3389/fimmu.2017.00846. eCollection 2017.
Impact factor: 6.429
Publication type: Review in international publication
Authors: Guilarte, Mar, Sala-Cunill, Anna, Luengo, Olga, Labrador-Horrillo, Moises, Cardona, Victoria et al.
DOI: 10.3389/fimmu.2017.00846

Vaccination and allergy: EAACI position paper, practical aspects.

PMID: 28779496
Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY
Year: 2017
Reference: Pediatr Allergy Immunol. 2017 Nov;28(7):628-640. doi: 10.1111/pai.12762. Epub 2017 Oct 10.
Impact factor: 3.775
Publication type: Review in national publication
Authors: Storsaeter, Jann, Nilsson, Lennart, Brockow, Knut, Alm, Johan, Cardona, Victoria, Caubet, Jean-Christoph, Gomes, Eva, Jenmalm, Maria C, Lau, Susanne, Netterlid, Eva et al.
DOI: 10.1111/pai.12762

Inappropriate prescribing in elderly people with diabetes admitted to hospital.

PMID: 26333026
Journal: DIABETIC MEDICINE
Year: 2016
Reference: Diabet Med. 2016 May;33(5):655-62. doi: 10.1111/dme.12894. Epub 2015 Oct 18.
Impact factor: 3.152
Publication type: Paper in international publication
Authors: Formiga, F, Vidal, X, Agusti, A, Chivite, D, Roson, B, Ponte, Paola, Ortiz, Gabriel, Cobas, Paula-Carlota Rivas, Gil, Paloma, Turbau, Miquel et al.
DOI: 10.1111/dme.12894

A 40-Year-Old Woman With Back Pain.

PMID: 27938773
Journal: CHEST
Year: 2016
Reference: Chest. 2016 Dec;150(6):e159-e165. doi: 10.1016/j.chest.2016.08.1449.
Impact factor: 5.94
Publication type: Paper in international publication
Authors: Fernandez-Codina, Andreu, Aranda-Rodriguez, Santiago, Romagosa, Cleofe, Deu-Martin, Maria, Parra-Farinas, Carmen, Bujan-Rivas, Segundo et al.
DOI: 10.1016/j.chest.2016.08.1449

A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis.

PMID: 27716427
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2016
Reference: Arthritis Res Ther. 2016 Oct 4;18(1):221.
Impact factor: 3.979
Publication type: Paper in international publication
Authors: Torices, Silvia, Julia, Antonio, Munoz, Pedro, Varela, Ignacio, Balsa, Alejandro, Marsal, Sara, Fernandez-Nebro, Antonio, Blanco, Francisco, Lopez-Hoyos, Marcos, Martinez-Taboada, Victor et al.
DOI: 10.1186/s13075-016-1113-z

Statin-associated autoimmune myopathy: A distinct new IFL pattern can increase the rate of HMGCR antibody detection by clinical laboratories.

PMID: 27640317
Journal: AUTOIMMUNITY REVIEWS
Year: 2016
Reference: Autoimmun Rev. 2016 Dec;15(12):1161-1166. doi: 10.1016/j.autrev.2016.09.005. Epub 2016 Sep 15.
Impact factor: 8.49
Publication type: Paper in international publication
Authors: Selva-O'Callaghan, A, Pujol-Borrell, R, Alvarado-Cardenas, M, Marin, A, Martinez, M A, Pinal-Fernandez, I, Labrador-Horrillo, M, Balada, E, Mundet-Tuduri, X, Gonzalez-Mera, L et al.
DOI: 10.1016/j.autrev.2016.09.005

Delayed diagnosis of late-onset Pompe disease in patients with myopathies of unknown origin and/or hyperCKemia.

PMID: 25752415
Journal: MOLECULAR GENETICS AND METABOLISM
Year: 2015
Reference: Mol Genet Metab. 2015 Apr;114(4):580-3. doi: 10.1016/j.ymgme.2015.02.004. Epub 2015 Feb 21.
Impact factor: 2.625
Publication type: Paper in international publication
Authors: Perez-Lopez, Jordi, Selva-O'Callaghan, Albert, Grau-Junyent, Josep M, Gallego-Galindo, Luis, Coll, M Josep, Garcia-Morillo, Salvador, Torralba-Cabeza, Miguel A, Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.ymgme.2015.02.004

IgG4-Related Disease: Results From a Multicenter Spanish Registry.

PMID: 26266361
Journal: MEDICINE
Year: 2015
Reference: Medicine (Baltimore). 2015 Aug;94(32):e1275. doi: 10.1097/MD.0000000000001275.
Impact factor: 5.723
Publication type: Paper in international publication
Authors: DeTorres, Ines, Solans-Laque, Roser, Fraile-Rodriguez, Guadalupe, Casanovas-Martinez, Arnau, Lopez-Dupla, Miguel, Robles-Marhuenda, Angel, Barragan-Gonzalez, Maria Jesus, Cid, Maria Cinta, Prieto-Gonzalez, Sergio, Brito-Zeron, Pilar et al.
DOI: 10.1097/MD.0000000000001275

Increased humoral immunity in the jejunum of diarrhoea-predominant irritable bowel syndrome associated with clinical manifestations.

PMID: 25209656
Journal: GUT
Year: 2015
Reference: Gut. 2015 Sep;64(9):1379-88. doi: 10.1136/gutjnl-2013-306236. Epub 2014 Sep 10.
Impact factor: 13.319
Publication type: Paper in international publication
Authors: Vicario, Maria, Gonzalez-Castro, Ana M, Martinez, Cristina, Lobo, Beatriz, Pigrau, Marc, Guilarte, Mar, de Torres, Ines, Mosquera, Jose L, Fortea, Marina, Sevillano-Aguilera, Cesar et al.
DOI: 10.1136/gutjnl-2013-306236

Intrapleural Fibrinolysis with Urokinase Versus Alteplase in Complicated Parapneumonic Pleural Effusions and Empyemas: A Prospective Randomized Study.

PMID: 26423784
Journal: LUNG
Year: 2015
Reference: Lung. 2015 Dec;193(6):993-1000. doi: 10.1007/s00408-015-9807-6. Epub 2015 Sep 30.
Impact factor: 2.271
Publication type: Paper in international publication
Authors: Martinez-Sogues, Mireia, Lopez, Iker, Pallisa, Esther, Schoenenberger, Joan Antoni, Bruno Montoro, J, de Sevilla, Tomas Fernandez, Sune, Pilar, Deu, Maria, Bielsa, Silvia, Aleman, Carmen et al.
DOI: 10.1007/s00408-015-9807-6

Acute and long-term management of food allergy: systematic review.

PMID: 24215577
Journal: ALLERGY
Year: 2014
Reference: Allergy. 2014 Feb;69(2):159-67. doi: 10.1111/all.12314. Epub 2013 Nov 12.
Impact factor: 5.995
Publication type: Review in national publication
Authors: Akdis, C A, de Silva, D, Geromi, M, Panesar, S S, Muraro, A, Werfel, T, Hoffmann-Sommergruber, K, Roberts, G, Cardona, V, Dubois, A E J et al.
DOI: 10.1111/all.12314

The epidemiology of food allergy in Europe: a systematic review and meta-analysis.

PMID: 24205824
Journal: ALLERGY
Year: 2014
Reference: Allergy. 2014 Jan;69(1):62-75. doi: 10.1111/all.12305. Epub 2013 Nov 11.
Impact factor: 5.995
Publication type: Review in national publication
Authors: Sheikh, A, Vlieg-Boerstra, B J, Roberts, G, Nwaru, B I, Hickstein, L, Panesar, S S, Muraro, A, Werfel, T, Cardona, V, Dubois, A E J et al.
DOI: 10.1111/all.12305

International consensus on (ICON) anaphylaxis.

PMID: 24920969
Journal: World Allergy Organization Journal
Year: 2014
Reference: World Allergy Organ J. 2014 May 30;7(1):9. doi: 10.1186/1939-4551-7-9. eCollection 2014.
Impact factor: 0.44
Publication type: Paper in international publication
Authors: Simons, F Estelle R, Ardusso, Ledit Rf, Bilo, M Beatrice, Cardona, Victoria, Ebisawa, Motohiro, El-Gamal, Yehia M, Lieberman, Phil, Lockey, Richard F, Muraro, Antonella, Roberts, Graham et al.
DOI: 10.1186/1939-4551-7-9

Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology.

PMID: 24909803
Journal: ALLERGY
Year: 2014
Reference: Allergy. 2014 Aug;69(8):1026-45. doi: 10.1111/all.12437. Epub 2014 Jun 9.
Impact factor: 5.995
Publication type: Clinical guide
Authors: Fernandez Rivas, M, Santos, A F, Zolkipli, Z Q, Bellou, A, Beyer, K, Bindslev-Jensen, C, Cardona, V, Clark, A T, Demoly, P, Dubois, A E J et al.
DOI: 10.1111/all.12437

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome.

PMID: 23514202
Journal: Journal of Translational Medicine
Year: 2013
Reference: J Transl Med. 2013 Mar 20;11:68. doi: 10.1186/1479-5876-11-68.
Impact factor: 3.459
Publication type: Paper in international publication
Authors: Curriu, Marta, Carrillo, Jorge, Massanella, Marta, Rigau, Josepa, Alegre, Jose, Puig, Jordi, Garcia-Quintana, Ana M, Castro-Marrero, Jesus, Negredo, Eugenia, Clotet, Bonaventura et al.
DOI: 10.1186/1479-5876-11-68

Erdheim-Chester disease.

PMID: 23505236
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2013
Reference: Ann Rheum Dis. 2013 Jun;72(6):e10. doi: 10.1136/annrheumdis-2013-203519. Epub 2013 Mar 16.
Impact factor: 9.111
Publication type: Letter whit IF
Authors: Juanos-Iborra, Montserrat, Solanich-Moreno, Javier, Selva-O'Callaghan, Albert et al.
DOI: 10.1136/annrheumdis-2013-203519

Could mitochondrial dysfunction be a differentiating marker between Chronic Fatigue Syndrome and Fibromyalgia?

PMID: 23600892
Journal: ANTIOXIDANTS & REDOX SIGNALING
Year: 2013
Reference: Antioxid Redox Signal. 2013 Nov 20;19(15):1855-60. doi: 10.1089/ars.2013.5346. Epub 2013 May 29.
Impact factor: 7.189
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Cordero, Mario D, Saez-Francas, Naia, Jimenez-Gutierrez, Conxita, Aguilar-Montilla, Francisco J, Aliste, Luisa, Alegre-Martin, Jose et al.
DOI: 10.1089/ars.2013.5346

Calcineurin inhibitors in a cohort of patients with antisynthetase-associated interstitial lung disease.

PMID: 23465087
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2013
Reference: Clin Exp Rheumatol. 2013 May-Jun;31(3):436-9. Epub 2013 Mar 7.
Impact factor: 2.655
Publication type: Paper in international publication
Authors: Labrador-Horrillo, Moises, Vilardell-Tarres, Miquel, Trallero-Araguas, Ernesto, Martinez-Gomez, Xavier, Labirua-Iturburu, Ane, Selva-O'Callaghan, Albert et al.
DOI:

Analysis of mite allergic patients in a diverse territory by improved diagnostic tools.

PMID: 22702511
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2012
Reference: Clin Exp Allergy. 2012 Jul;42(7):1129-38. doi: 10.1111/j.1365-2222.2012.03993.x.
Impact factor: 5.032
Publication type: Paper in international publication
Authors: Barber, D, Arias, J, Boquete, M, Cardona, V, Carrillo, T, Gala, G, Gamboa, P, C Garcia-Robaina, J, Hernandez, D, L Sanz, M et al.
DOI: 10.1111/j.1365-2222.2012.03993.x

[A 37-years old man with recurrent episodes of fever and abdominal pain.]

PMID: 22672967
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Oct 6;139(8):348-53. doi: 10.1016/j.medcli.2012.03.017. Epub 2012 Jun 4.
Impact factor: 1.385
Publication type: Editorial in national publication
Authors: , et al.
DOI: 10.1016/j.medcli.2012.03.017

Involvement of Can f 5 in a Case of Human Seminal Plasma Allergy.

PMID: 22653399
Journal: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Year: 2012
Reference: Int Arch Allergy Immunol. 2012;159(2):143-6. doi: 10.1159/000336388. Epub 2012 May 30.
Impact factor: 2.403
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1159/000336388

Can we predict the severity of pulmonary hypertension in patients with scleroderma?

PMID: 22658662
Journal: Reumatologia clinica
Year: 2012
Reference: Reumatol Clin. 2012 Sep-Oct;8(5):259-62. Epub 2012 May 31.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , , et al.
DOI: 10.1016/j.reuma.2012.03.007

[Tracheobronchial involvement in Wegener's granulomatosis.]

PMID: 21450317
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Jul 23;137(5):230-5. Epub 2011 Mar 29.
Impact factor: 1.413
Publication type: Editorial in national publication
Authors: , , et al.
DOI: 10.1016/j.medcli.2011.01.007

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort.

PMID: 21187296
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2011
Reference: Ann Rheum Dis. 2011 Apr;70(4):638-41. Epub 2010 Dec 27.
Impact factor: 9.082
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/ard.2010.141838

Efficacy of Cyclophospamide in the Treatment of Interstitial Lung Disease Associated with Systemic Sclerosis.

PMID: 21458128
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2011
Reference: Arch Bronconeumol. 2011 May;47(5):239-45. Epub 2011 Mar 31.
Impact factor:
Publication type: Letter or abstract
Authors: , , , , , , , et al.
DOI: 10.1016/j.arbres.2011.01.010

Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis.

PMID: 21131644
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2011
Reference: Ann Rheum Dis. 2011 Mar;70(3):454-62. Epub 2010 Dec 3.
Impact factor: 9.082
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/ard.2010.130138

Loss of imprinting of IGF2 characterises high IGF2 mRNA-expressing type of fibroblast-like synoviocytes in rheumatoid arthritis.

PMID: 19556211
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2010
Reference: Ann Rheum Dis. 2010 Jun;69(6):1239-42. Epub 2009 Jun 24.
Impact factor: 8.111
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/ard.2008.106195

Anti-annexin A5 antibodies in women with spontaneous pregnancy loss.

PMID: 20022614
Journal: MEDICINA CLINICA
Year: 2010
Reference: Med Clin (Barc). 2010 Apr 10;134(10):433-438. Epub 2009 Dec 22.
Impact factor: 1.231
Publication type: Paper in national publication
Authors: , , Alijotas Reig, Jaume, , , , , et al.
DOI: 10.1016/j.medcli.2009.09.040

Three-dimensional volumetric ultrasonography. Does it improve reliabililty of musculoskeletal ultrasound?

PMID: 20346243
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2010
Reference: Clin Exp Rheumatol. 2010 Jan-Feb;28(1):79-82.
Impact factor: 2.396
Publication type: Paper in international publication
Authors: Uson, Jacqueline, Naredo, Esperanza, Moller, Ingrid, Acebes, Carlos, Batlle-Gualda, Enrique, Brito, Elia, de Agustin, Juan Jose, de Miguel, Eugenio, Martinez, Agustin, Mayordomo, Lucia et al.
DOI:

Autoimmune diseases induced by biological agents: a double-edged sword?

PMID: 19854301
Journal: AUTOIMMUNITY REVIEWS
Year: 2010
Reference: Autoimmun Rev. 2010 Jan;9(3):188-93. Epub 2009 Oct 23.
Impact factor: 6.368
Publication type: Paper in international publication
Authors: Callejas, J L, Ramos-Casals, Manuel, , Diaz-Lagares, Candido, Cuadrado, Maria-Jose, Khamashta, Munther A, Ramos-Casals, M, Ayala, M M, Brito-Zeron, P, Tolosa, C et al.
DOI: 10.1016/j.autrev.2009.10.003

Epstein-Barr virus-associated lymphoma in patients with dermatomyositis. Be aware of double immunosuppression.

PMID: 19696063
Journal: RHEUMATOLOGY
Year: 2009
Reference: Rheumatology (Oxford). 2009 Nov;48(11):1462-3.
Impact factor: 4.136
Publication type: Letter or abstract
Authors: Selva-O'Callaghan, Albert, Palacios, Andres, Solans-Laque, Roser, Labirua, Anne, Salcedo-Allende, Teresa, Vilardell-Tarres, Miquel et al.
DOI: 10.1093/rheumatology/kep247

Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity.

PMID: 19714703
Journal: REVIEWS IN MEDICAL VIROLOGY
Year: 2009
Reference: Rev Med Virol. 2009 Sep;19(5):273-86.
Impact factor: 7.13
Publication type: Review in international publication
Authors: Balada, Eva, Ordi-Ros, Josep, Vilardell-Tarres, Miquel et al.
DOI: 10.1002/rmv.622

The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype.

PMID: 19286670
Journal: HUMAN MOLECULAR GENETICS
Year: 2009
Reference: Hum Mol Genet. 2009 Jun 1;18(11):2071-7.
Impact factor: 7.249
Publication type: Paper in international publication
Authors: Ortego-Centeno, N, Riemekasten, G, Fonollosa, V, Vonk, M C, van den Hoogen, F H J, Sanchez-Roman, J, Aguirre-Zamorano, M A, Garcia-Portales, R, Pros, A, Camps, M T et al.
DOI: 10.1093/hmg/ddp119

A large multicentre analysis of CTGF -945 promoter polymorphism does not confirm association with systemic sclerosis susceptibility or phenotype.

PMID: 19054816
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2009
Reference: Ann Rheum Dis. 2009 Oct;68(10):1618-20.
Impact factor: 7.188
Publication type: Paper in international publication
Authors: van den Hoogen, F H J, Sanchez-Roman, J, Aguirre-Zamorano, M A, Garcia-Portales, R, Pros, A, Camps, M T, Gonzalez-Gay, M A, Gonzalez-Escribano, M F, Coenen, M J, Lambert, N et al.
DOI: 10.1136/ard.2008.100180

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The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.