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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Research lines

Serological markers study in anaphylaxis.

We are performing a follow up study of different serological markers in patients who have suffered some anaphylactic episodes. The main goal consists on detecting anaphylaxis patients at the intensive care unit and to determine different serological and plasma markers, mainly tryptase and carboxypeptidase levels by means of a sandwich ELISA.

IP: Moisés Labrador Horrillo

Significance of Capillaroscopy in Raynaud's phenomenon and scleroderma.

We want to describe the capillaroscopy alterations observed in patients with Raynaud's phenomenon and scleroderma. Our main objective is to establish the different patterns that may be related to visceral involvement and to the prognosis in the early stages of the disease.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Spanish Registry of patients with Behçet disease (REGEB).

This is a multicentre study supported by the Systemic Autoimmune Diseases Group from the Spanish Internal Medicine Society. The aim of the study is to describe the different clinical forms of disease presentation in our country and the response of the disease to conventional treatment.

IP: Roser Solans Laque

Spanish Registry of patients with primary Sjögren’s syndrome.

This is a multicentre study supported by the Systemic Autoimmune Diseases Group (GEAS) from the Spanish Internal Medicine Society (SEMI). Its main goal consist in investigate the factors involved in extraglandular development in our country. This study is coordinated by Dr. Manel Ramos  from the Clinic Hospital, Barcelona.

IP: Roser Solans Laque

Publications

Efficacy and Safety of Anakinra Plus Standard of Care for Patients With Severe COVID-19: A Randomized Phase 2/3 Clinical Trial.

PMID: 37027155
Journal: JAMA Network Open
Year: 2023
Reference: JAMA Netw Open. 2023 Apr 3;6(4):e237243. doi: 10.1001/jamanetworkopen.2023.7243.
Impact factor:
Publication type: Paper in international publication
Authors: Abdilla-Bonias, Noelia; Alende-Sixto, Rosario; Alvarez-Suarez, Ana Maria; Alvarez-Troncoso, Jorge; Andrade-Pina, Ariadna Helena; Arevalo, Coral; Argibay, Ana Belen; Arnaez, Ruben; Arnalich, Francisco; Bara, Nuria et al.
DOI: 10.1001/jamanetworkopen.2023.7243

Low complement levels are related to poor obstetric outcomes in women with obstetric antiphospholipid syndrome. The EUROAPS Registry Study Group.

PMID: 37028222
Journal: PLACENTA
Year: 2023
Reference: Placenta. 2023 May;136:29-34. doi: 10.1016/j.placenta.2023.04.001. Epub 2023 Apr 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume; Anunciacion-Llunell, Ariadna; Arnau, Anna; Belizna, Cristina; Canti, Valentina; Cervera, Ricard; Chighizola, Cecilia B; De Carolis, Sara; Espinosa, Gerard; Esteve-Valverde, Enrique et al.
DOI: 10.1016/j.placenta.2023.04.001

Impact of the COVID-19 pandemic in the early-onset colorectal cancer.

PMID: 37031602
Journal: Translational Oncology
Year: 2023
Reference: Transl Oncol. 2023 Jun;32:101668. doi: 10.1016/j.tranon.2023.101668. Epub 2023 Apr 5.
Impact factor:
Publication type: Paper in international publication
Authors: Baraibar, Iosune; Capdevila, Jaume; Castells, Marta R; Castillo, Gloria; Comas, Raquel; Comas, Raquel; Dopazo, Cristina; Elez, Elena; Espin, Eloy; Garcia, Ariadna et al.
DOI: 10.1016/j.tranon.2023.101668

Patient-centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA-EAACI approach.

PMID: 37042071
Journal: ALLERGY
Year: 2023
Reference: Allergy. 2023 Apr 11. doi: 10.1111/all.15740.
Impact factor:
Publication type: Review in international publication
Authors: Amaral, Rita; Ansotegui, Ignacio J; Anto, Josep M; Barbara, Cristina; Bedbrook, Anna; Bergmann, Karl C; Bewick, Michael; Blain, Hubert; Bonini, Matteo; Bosnic-Anticevich, Sinthia et al.
DOI: 10.1111/all.15740

Consensus on the definition of disease control and response assessment in chronic urticaria.

PMID: 35503509
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Investig Allergol Clin Immunol. 2022 Jul 22;32(4):261-269. doi: 10.18176/jiaci.0820. Epub 2022 May 3.
Impact factor:
Publication type: Review in international publication
Authors: Bartra, J; Ferrer, M; Gimenez-Arnau, A M; Jauregui, I; Labrador-Horrillo, M; Miquel Miquel, J; Ortiz de Frutos, F J; Sastre, J; Silvestre-Salvador, J F; Valero, A et al.
DOI: 10.18176/jiaci.0820

Clinical features and outcomes of COVID-19 in patients with IgG4-related disease: a European multi-center study.

PMID: 34919665
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 May 5;61(5):e109-e111. doi: 10.1093/rheumatology/keab930.
Impact factor:
Publication type: Paper in international publication
Authors: Culver, Emma L; Dagna, Lorenzo; Della-Torre, Emanuel; Ebbo, Mikael; Fernandez-Codina, Andreu; Lanzillotta, Marco; Mancuso, Gaia; Martinez-Valle, Fernando; Orozco-Galvez, Olimpia; Ramirez, Giuseppe A et al.
DOI: 10.1093/rheumatology/keab930

Is humoral and cellular response to SARS-CoV-2 vaccine modified by DMT in patients with multiple sclerosis and other autoimmune diseases?

PMID: 35475363
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27.
Impact factor:
Publication type: Paper in international publication
Authors: Agraz, Irene; Alvarez, Gary; Arrambide, Georgina; Bertran, Jordina; Bonastre, Merce; Carbonell-Mirabent, Pere; Cardenas-Robledo, Simon; Castillo, Joaquin; Castillo, Mireia; Cobo-Calvo, Alvaro et al.
DOI: 10.1177/13524585221089540

Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency.

PMID: 35464398
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Apr 8;13:881206. doi: 10.3389/fimmu.2022.881206. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilo-Cucurull, Aina; Antolin, Maria; Colobran, Roger; Franco-Jarava, Clara; Garcia-Prat, Marina; Labrador-Horrillo, Moises; Martinez-Gallo, Monica; Parra-Martinez, Alba; Salgado-Perandres, Sandra et al.
DOI: 10.3389/fimmu.2022.881206

Update on latex allergy: New insights into an old problem.

PMID: 34386153
Journal: World Allergy Organization Journal
Year: 2021
Reference: World Allergy Organ J. 2021 Jul 28;14(8):100569. doi: 10.1016/j.waojou.2021.100569. eCollection 2021 Aug.
Impact factor:
Publication type: Review in international publication
Authors: Acuna-Ortega, Natalhie; Ansotegui, Ignacio J; Bilo, Maria Beatrice; Braschi, Maria Chiara; Cardona, Victoria; Gonzalez-Diaz, Sandra Nora; Kelly, Kevin J; Macias-Weinmann, Alejandra; Parisi, Claudio A S; Park, Hae-Sim et al.
DOI: 10.1016/j.waojou.2021.100569

Role of autoantibodies in the diagnosis and prognosis of interstitial lung disease in autoimmune rheumatic disorders.

PMID: 34377160
Journal: Therapeutic Advances in Musculoskeletal Disease
Year: 2021
Reference: Ther Adv Musculoskelet Dis. 2021 Jul 27;13:1759720X211032457. doi: 10.1177/1759720X211032457. eCollection 2021.
Impact factor:
Publication type: Review in international publication
Authors: Gil-Vila, Albert; Kuwana, Masataka; Selva-O'Callaghan, Albert et al.
DOI: 10.1177/1759720X211032457

Circulating Cell Biomarkers in Pulmonary Arterial Hypertension: Relationship with Clinical Heterogeneity and Therapeutic Response.

PMID: 34359858
Journal: Cells
Year: 2021
Reference: Cells. 2021 Jul 4;10(7). pii: cells10071688. doi: 10.3390/cells10071688.
Impact factor:
Publication type: Paper in international publication
Authors: Barbera, Joan Albert; Blanco, Isabel; Crespo, Isabel; Del Pozo, Roberto; Ferrer, Elisabet; Garcia, Agustin Roberto; Garcia-Lucio, Jessica; Lopez-Meseguer, Manuel; Martin-Ontiyuelo, Clara; Peinado, Victor I et al.
DOI: 10.3390/cells10071688

Milestones of Precision Medicine: An Innovative, Multidisciplinary Overview.

PMID: 34331269
Journal: Molecular Diagnosis & Therapy
Year: 2021
Reference: Mol Diagn Ther. 2021 Sep;25(5):563-576. doi: 10.1007/s40291-021-00544-4. Epub 2021 Jul 30.
Impact factor:
Publication type: Review in international publication
Authors: Argente, Jesus; Bujanda, Luis; Cardona, Victoria; Casanova, Bonaventura; Fernandez-Montes, Ana; Garcia-Foncillas, Jesus; Horcajadas, Jose A; Iniguez, Andres; Ortiz, Alberto; Pablos, Jose L et al.
DOI: 10.1007/s40291-021-00544-4

Application of specific-to-total IgE ratio does not benefit diagnostic performance of serologic testing for rocuronium allergy.

PMID: 32620258
Journal: BRITISH JOURNAL OF ANAESTHESIA
Year: 2020
Reference: Br J Anaesth. 2020 Dec;125(6):e443-e446. doi: 10.1016/j.bja.2020.05.032. Epub 2020 Jun 30.
Impact factor:
Publication type: Letter or abstract
Authors: De Puysseleyr, Leander; Ebo, Didier G; Elst, Jessy; Faber, Margaretha A; Hagendorens, Margo M; Horiuchi, Tatsuo; Mertens, Christel M; Molina-Molina, Gustavo; Sabato, Vito; Van Der Poorten, Marie-Line M et al.
DOI: 10.1016/j.bja.2020.05.032

Comparison of the birmingham vasculitis activity score and the five factors score to assess survival in anca-associated vasculitis.

PMID: 31033198
Journal: ARTHRITIS CARE & RESEARCH
Year: 2020
Reference: Arthritis Care Res (Hoboken). 2020 Jul;72(7):1001-1010. doi: 10.1002/acr.23912. Epub 2020 Jun 12.
Impact factor:
Publication type: Paper in international publication
Authors: Abdilla, Monica; Callejas, Jose Luis; Castillo, Maria Jesus; Fanlo, Patricia; Fonseca-Aizpuru, Eva; Fraile, Guadalupe; Frutos, Begona; Garcia-Sanchez, Isabel; Lopez-Dupla, Miguel; Martinez-Zapico, Aleida et al.
DOI: 10.1002/acr.23912

Autoantibodies to stratify systemic sclerosis patients into clinically actionable subsets.

PMID: 32553611
Journal: AUTOIMMUNITY REVIEWS
Year: 2020
Reference: Autoimmun Rev. 2020 Aug;19(8):102583. doi: 10.1016/j.autrev.2020.102583. Epub 2020 Jun 14.
Impact factor:
Publication type: Review in international publication
Authors: Bentow, Chelsea; Beretta, Lorenzo; Casas, Silva; Fritzler, Marvin J; Guillen-Del-Castillo, Alfredo; Hudson, Marie; Mahler, Michael; Roup, Fabrece; Simeon, Carmen Pilar et al.
DOI: 10.1016/j.autrev.2020.102583

Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis.

PMID: 32546599
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2020
Reference: Ann Rheum Dis. 2020 Sep;79(9):1234-1242. doi: 10.1136/annrheumdis-2019-216599. Epub 2020 Jun 16.
Impact factor:
Publication type: Paper in international publication
Authors: Albayda, Jemima; Carrion-Ribas, Carme; Casal-Dominguez, Maria; Christopher-Stine, Lisa; Corse, Andrea M; Derfoul, Assia; Grau-Junyent, Josep Maria; Lloyd, Thomas E; Mammen, Andrew L; Milisenda, Jose Cesar et al.
DOI: 10.1136/annrheumdis-2019-216599

Characteristics, quality of life and control of respiratory allergic diseases caused by house dust mites (HDMs) in Spain: a cross-sectional study.

PMID: 31406567
Journal: Clinical and Translational Allergy
Year: 2019
Reference: Clin Transl Allergy. 2019 Aug 6;9:39. doi: 10.1186/s13601-019-0276-5. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Aldunate, Maria Teresa; Alvarez, Jose Antonio; Ana, Beristain; Ano, Miguel; Campos, Gonzalo; Cardona, Victoria; Cruz, Sergia; de la Torre, Fernando; De Luque, Virginia; Domenech, Joan et al.
DOI: 10.1186/s13601-019-0276-5

[Very elderly institutionalised population of Barcelona: Evaluation of frailty according to the Frail-VIG index and analysis of therapeutic appropriateness according to the STOPP-frail criteria].

PMID: 31362844
Journal: Revista espanola de geriatria y gerontologia
Year: 2019
Reference: Rev Esp Geriatr Gerontol. 2019 Nov - Dec;54(6):334-338. doi: 10.1016/j.regg.2019.06.004. Epub 2019 Jul 28.
Impact factor:
Publication type: Paper in national publication
Authors: Curto Prieto, David; Formiga, Francesc; Mundet Riera, Imma; San Jose Laporte, Antonio; Vivanco, Maria Victoria et al.
DOI: 10.1016/j.regg.2019.06.004

An Exosomal Urinary miRNA Signature for Early Diagnosis of Renal Fibrosis in Lupus Nephritis.

PMID: 31349698
Journal: Cells
Year: 2019
Reference: Cells. 2019 Jul 25;8(8). pii: cells8080773. doi: 10.3390/cells8080773.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Moline, Teresa; Ordi-Ros, Josep; Sole, Cristina; Vidal, Marta et al.
DOI: 10.3390/cells8080773

Effectiveness of a multidisciplinary educational intervention in patients with hip fracture: SWEET HOME study.

PMID: 31320135
Journal: MEDICINA CLINICA
Year: 2019
Reference: Med Clin (Barc). 2019 Dec 27;153(12):446-453. doi: 10.1016/j.medcli.2019.02.026. Epub 2019 Jul 16.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez-Lorenzo, Consuelo; Garrido-Clua, Miriam; Gines-Puertas, Alex; Lalueza-Broto, Pilar; Mestre-Torres, Jaume; Molero-Garcia, Vicente; Ponce-Ruiz, Sandra; Ramentol-Sintas, Marc; Sanchez-Raya, Judith; Sanclemente-Boli, Teresa et al.
DOI: 10.1016/j.medcli.2019.02.026

Cancer-associated Dermatomyositis: Does the PD-1 Checkpoint Pathway Play a Role?

PMID: 29858454
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2018
Reference: J Rheumatol. 2018 Jun;45(6):731-732. doi: 10.3899/jrheum.180007.
Impact factor:
Publication type: Editorail in international publication
Authors: Labrador-Horrillo, Moises; Selva-O'Callaghan, Albert et al.
DOI: 10.3899/jrheum.180007

Poor self-reported sleep quality and health-related quality of life in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

PMID: 29770505
Journal: JOURNAL OF SLEEP RESEARCH
Year: 2018
Reference: J Sleep Res. 2018 Dec;27(6):e12703. doi: 10.1111/jsr.12703. Epub 2018 May 16.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Aliste, Luisa; Castro-Marrero, Jesus; Fernandez de Sevilla, Tomas; Ferre, Alex; Gonzalez-Garcia, Sergio; Romero, Odile; Saez-Francas, Naia; Zaragoza, Maria C et al.
DOI: 10.1111/jsr.12703

Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes.

PMID: 29768139
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 May 17;378(20):1908-1919. doi: 10.1056/NEJMoa1706314.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Jordi; Ben-Chetrit, Eldad; Brogan, Paul; Bujan-Rivas, Segundo; Calvo Penades, Inmaculada; Cattalini, Marco; Constantin, Tamas; De Benedetti, Fabrizio; Frenkel, Joost; Gattorno, Marco et al.
DOI: 10.1056/NEJMoa1706314

Venous thrombosis and relapses in patients with Behcet's disease. Descriptive analysis from Spanish network of Behcet's disease (REGEB cohort).

PMID: 29745871
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2018
Reference: Clin Exp Rheumatol. 2018 Nov-Dec;36 Suppl 115(6):40-44. Epub 2018 May 3.
Impact factor:
Publication type: Paper in international publication
Authors: Boldova, Rafael; de Escalante, Begona; Espinosa, Gerard; Fonseca, Eva; Fraile, Guadalupe; Garcia-Hernandez, Francisco Javier; Hurtado, Robert; Larranaga, Jose Ramon; Martinez-Valle, Ferran; Munoz, Francisco Jose et al.
DOI:

Vaccination and allergy: EAACI position paper, practical aspects.

PMID: 28779496
Journal: PEDIATRIC ALLERGY AND IMMUNOLOGY
Year: 2017
Reference: Pediatr Allergy Immunol. 2017 Nov;28(7):628-640. doi: 10.1111/pai.12762. Epub 2017 Oct 10.
Impact factor:
Publication type: Review in national publication
Authors: Alm, Johan; Brockow, Knut; Cardona, Victoria; Caubet, Jean-Christoph; Gomes, Eva; Jenmalm, Maria C; Lau, Susanne; Netterlid, Eva; Nilsson, Lennart; Schwarze, Jurgen et al.
DOI: 10.1111/pai.12762

RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis.

PMID: 28738907
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2017
Reference: Arthritis Res Ther. 2017 Jul 24;19(1):174. doi: 10.1186/s13075-017-1383-0.
Impact factor:
Publication type: Paper in international publication
Authors: Castellvi, Ivan; De Luna, Noemi; Diaz-Manera, Jordi; Gallardo, Eduard; Grau, Josep M; Illa, Isabel; Lleixa, Cinta; Martinez, M Angeles; Pinal-Fernandez, Iago; Rojas-Garcia, Ricardo et al.
DOI: 10.1186/s13075-017-1383-0

Acquired thrombotic thrombocytopenic purpura and pregnancy: More light than shade but controversies remain.

PMID: 28697902
Journal: THROMBOSIS RESEARCH
Year: 2017
Reference: Thromb Res. 2017 Aug;156:195-197. doi: 10.1016/j.thromres.2017.07.005. Epub 2017 Jul 5.
Impact factor:
Publication type: Editorail in international publication
Authors: Alijotas-Reig, Jaume et al.
DOI: 10.1016/j.thromres.2017.07.005

An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis.

PMID: 28668810
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2017
Reference: J Rheumatol. 2017 Oct;44(10):1453-1457. doi: 10.3899/jrheum.161369. Epub 2017 Jul 1.
Impact factor:
Publication type: Paper in international publication
Authors: Airo, Paolo; Beretta, Lorenzo; Bossini-Castillo, Lara; Callejas-Rubio, Jose Luis; Campillo-Davo, Diana; Carmona, Francisco David; Carreira, Patricia; Castellvi, Ivan; de Vries-Bouwstra, J; Fernandez-Nebro, Antonio et al.
DOI: 10.3899/jrheum.161369

Defining disease activity states and clinically meaningful improvement in primary Sjogren's syndrome with EULAR primary Sjogren's syndrome disease activity (ESSDAI) and patient-reported indexes (ESSPRI).

PMID: 25480887
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2016
Reference: Ann Rheum Dis. 2016 Feb;75(2):382-9. doi: 10.1136/annrheumdis-2014-206008. Epub 2014 Dec 5.
Impact factor:
Publication type: Paper in international publication
Authors: Baron, Gabriel; Bartoloni, Elena; Bartoloni, Elena; Bombardieri, Stefano; Bombardieri, Stefano; Bootsma, Hendrika; Bootsma, Hendrika; Bowman, Simon J; Bowman, Simon J; Brito-Zeron, Pilar et al.
DOI: 10.1136/annrheumdis-2014-206008

Systemic activity and mortality in primary Sjogren syndrome: predicting survival using the EULAR-SS Disease Activity Index (ESSDAI) in 1045 patients.

PMID: 25433020
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2016
Reference: Ann Rheum Dis. 2016 Feb;75(2):348-55. doi: 10.1136/annrheumdis-2014-206418. Epub 2014 Nov 28.
Impact factor:
Publication type: Paper in international publication
Authors: Akasbi, M; Bosch, J A; Brito-Zeron, P; Casanovas, A; Diaz-Lopez, B; Fraile, G; Gheitasi, H; Kostov, B; Morera-Morales, M L; Nava-Mateos, J et al.
DOI: 10.1136/annrheumdis-2014-206418

Inappropriate prescribing in elderly people with diabetes admitted to hospital.

PMID: 26333026
Journal: DIABETIC MEDICINE
Year: 2016
Reference: Diabet Med. 2016 May;33(5):655-62. doi: 10.1111/dme.12894. Epub 2015 Oct 18.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cristina; Agusti, A; Ballarin, Elena; Ballesteros, Isabel; Barbe, J; Bocanegra, Carmen Perez; Bosch, Xavier; Cabot, Carme; Chivite, D; Cobas, Paula-Carlota Rivas et al.
DOI: 10.1111/dme.12894

[Treatment with immunosuppressive and biologic drugs of pregnant women with systemic rheumatic or autoimmune disease].

PMID: 27389618
Journal: MEDICINA CLINICA
Year: 2016
Reference: Med Clin (Barc). 2016 Oct 21;147(8):352-360. doi: 10.1016/j.medcli.2016.05.020. Epub 2016 Jul 5.
Impact factor:
Publication type: Review in national publication
Authors: Alijotas-Reig, Jaume; Esteve-Valverde, Enrique; Ferrer-Oliveras, Raquel et al.
DOI: 10.1016/j.medcli.2016.05.020

Increased humoral immunity in the jejunum of diarrhoea-predominant irritable bowel syndrome associated with clinical manifestations.

PMID: 25209656
Journal: GUT
Year: 2015
Reference: Gut. 2015 Sep;64(9):1379-88. doi: 10.1136/gutjnl-2013-306236. Epub 2014 Sep 10.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Carmen; Azpiroz, Fernando; de Torres, Ines; Fortea, Marina; Gonzalez-Castro, Ana M; Guilarte, Mar; Lobo, Beatriz; Martinez, Cristina; Mosquera, Jose L; Pigrau, Marc et al.
DOI: 10.1136/gutjnl-2013-306236

Hepatitis B virus quasispecies evolution after liver transplantation in patients under long-term lamivudine prophylaxis with or without hepatitis B immune globulin.

PMID: 25641570
Journal: TRANSPL INFECT DIS
Year: 2015
Reference: Transpl Infect Dis. 2015 Apr;17(2):208-20. doi: 10.1111/tid.12360.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, M; Casafont, F; Casillas, R; Castells, L; Esteban, R; Gonzalez, A; Herrero, J I; Homs, M; Mas, A; Miras, M et al.
DOI: 10.1111/tid.12360

Association of haplotypes of the TLR8 locus with susceptibility to Crohn's and Behcet's diseases.

PMID: 26486764
Journal: CLIN EXP RHEUMATOL
Year: 2015
Reference: Clin Exp Rheumatol. 2015 Nov-Dec;33(6 Suppl 94):S117-22. Epub 2015 Oct 19.
Impact factor:
Publication type: Paper in international publication
Authors: Barnosi-Marin, Ana-Celia; Blanco, Ricardo; Camps, Teresa; Castaneda, Santos; Conde-Jaldon, Marta; Espinosa, Gerard; Fanlo, Patricia; Garcia-Hernandez, Francisco-Jose; Garcia-Lozano, Jose-Raul; Gomez-Garcia, Maria et al.
DOI:

Applying the ACR/EULAR Systemic Sclerosis Classification Criteria to the Spanish Scleroderma Registry Cohort.

PMID: 26472418
Journal: J RHEUMATOL
Year: 2015
Reference: J Rheumatol. 2015 Dec;42(12):2327-31. doi: 10.3899/jrheum.150144. Epub 2015 Oct 15.
Impact factor:
Publication type: Paper in international publication
Authors: Colunga-Arguelles, Dolores; Egurbide-Arberas, Maria Victoria; Fonollosa-Pla, Vicent; Freire-Dapena, Mayka; Iniesta-Arandia, Nerea; Ortego-Centeno, Norberto; Perez-Conesa, Mercedes; Rios-Blanco, Juan Jose; Rubio-Rivas, Manuel; Saez-Comet, Luis et al.
DOI: 10.3899/jrheum.150144

Systemic sclerosis sine scleroderma and limited cutaneous systemic sclerosis: similarities and differences.

PMID: 24776173
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2014
Reference: Clin Exp Rheumatol. 2014 Nov-Dec;32 Suppl 86(6):33-40. Epub 2014 Apr 28.
Impact factor:
Publication type: Paper in international publication
Authors: Campillo-Grau, Mercedes; Fonollosa-Pla, Vincent; Gabarro-Julia, Lourdes; Guillen Del Castillo, Alfredo; Simeon-Aznar, Carmen Pilar; Tolosa-Vilella, Carles; Vilardell-Tarres, Miguel et al.
DOI:

Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease: a prospective study.

PMID: 24211744
Journal: JOURNAL OF HEPATOLOGY
Year: 2014
Reference: J Hepatol. 2014 Mar;60(3):561-9. doi: 10.1016/j.jhep.2013.10.027. Epub 2013 Nov 6.
Impact factor:
Publication type: Paper in international publication
Authors: Augustin, Salvador; Esteban, Rafael; Gelabert, Arantzazu; Genesca, Joan; Gonzalez, Antonio; Martell, Maria; Millan, Laura; Segarra, Antoni; Serres, Xavier et al.
DOI: 10.1016/j.jhep.2013.10.027

Good outcome of interstitial lung disease in patients with scleroderma associated to anti-PM/Scl antibody.

PMID: 25110305
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2014
Reference: Semin Arthritis Rheum. 2014 Dec;44(3):331-7. doi: 10.1016/j.semarthrit.2014.07.002. Epub 2014 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Vila, Serafin; Fernandez-Codina, Andreu; Fonollosa-Pla, Vicent; Guillen-Del Castillo, Alfredo; Munoz, Xavier; Pallisa, Esther; Pilar Simeon-Aznar, Carmen; Reverte-Vinaixa, Maria M; Selva-OCallaghan, Albert; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.semarthrit.2014.07.002

Neutrophil gelatinase-associated lipocalin as a biomarker for lupus nephritis.

PMID: 24711435
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2014
Reference: Nephrol Dial Transplant. 2014 Sep;29(9):1740-9. doi: 10.1093/ndt/gfu062. Epub 2014 Apr 7.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Ordi-Ros, Josep; Pedrosa Anna; Torres-Salido, Maria Teresa; Vidal, Xavier; Vilardell-Tarres, Miquel et al.
DOI: 10.1093/ndt/gfu062

Late-Onset Inflammatory Adverse Reactions Related to Soft Tissue Filler Injections.

PMID: 23361999
Journal: CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
Year: 2013
Reference: Clin Rev Allergy Immunol. 2013 Aug;45(1):97-108. doi: 10.1007/s12016-012-8348-5.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume; Fernandez-Figueras, Maria Teresa; Puig, Lluis et al.
DOI: 10.1007/s12016-012-8348-5

Validation of the first treatment-specific questionnaire for the assessment of patient satisfaction with allergen-specific immunotherapy in allergic patients: The ESPIA questionnaire.

PMID: 23352631
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2013
Reference: J Allergy Clin Immunol. 2013 Jun;131(6):1539-46. doi: 10.1016/j.jaci.2012.11.049. Epub 2013 Jan 23.
Impact factor:
Publication type: Paper in international publication
Authors: Baro, Eva; Cardona, Victoria; Garcia, Mario Alberto; Guardia, Pedro; Justicia, Jose Luis; Ojeda, Pedro; Olaguibel, Jose Maria; Vega, Jose Maria; Vidal, Carmen et al.
DOI: 10.1016/j.jaci.2012.11.049

Smoking during Pregnancy: Changes in Mid-Gestation Angiogenic Factors in Women at Risk of Developing Preeclampsia According to Uterine Artery Doppler Findings.

PMID: 22988942
Journal: HYPERTENSION IN PREGNANCY
Year: 2013
Reference: Hypertens Pregnancy. 2013;32(1):50-9. doi: 10.3109/10641955.2012.704107. Epub 2012 Sep 18.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume; Cabero, Lluis; Dominguez, Carmen; Goya, Maria; Llurba, Elisa; Sanchez, Olga; Soro, Gemma et al.
DOI: 10.3109/10641955.2012.704107

A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.

PMID: 22936669
Journal: GUT
Year: 2013
Reference: Gut. 2013 Oct;62(10):1440-5. doi: 10.1136/gutjnl-2012-302865. Epub 2012 Aug 30.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Alonso, Arnald; Andreu, Montserrat; Barreiro-de Acosta, Manuel; Bertanpetit, Jaume; Codo, Laia; Domenech, Eugeni; Esteve, Maria; Garcia-Montero, Andres C; Garcia-Planella, Esther et al.
DOI: 10.1136/gutjnl-2012-302865

[A 37-years old man with recurrent episodes of fever and abdominal pain.]

PMID: 22672967
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Oct 6;139(8):348-53. doi: 10.1016/j.medcli.2012.03.017. Epub 2012 Jun 4.
Impact factor:
Publication type: Editorial in national publication
Authors: ; et al.
DOI: 10.1016/j.medcli.2012.03.017

Can we predict the severity of pulmonary hypertension in patients with scleroderma?

PMID: 22658662
Journal: Reumatologia clinica
Year: 2012
Reference: Reumatol Clin. 2012 Sep-Oct;8(5):259-62. Epub 2012 May 31.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.reuma.2012.03.007

Involvement of Can f 5 in a Case of Human Seminal Plasma Allergy.

PMID: 22653399
Journal: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Year: 2012
Reference: Int Arch Allergy Immunol. 2012;159(2):143-6. doi: 10.1159/000336388. Epub 2012 May 30.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1159/000336388

[Update in hereditary angioedema due to C1 inhibitor deficiency.]

PMID: 22677048
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Oct 20;139(10):452-7. doi: 10.1016/j.medcli.2012.03.024. Epub 2012 Jun 5.
Impact factor:
Publication type: Editorial in national publication
Authors: et al.
DOI: 10.1016/j.medcli.2012.03.024

Xenotropic Murine Leukemia Virus-Related Virus (XMRV) in Patients with Systemic Lupus Erythematosus.

PMID: 21509625
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2011
Reference: J Clin Immunol. 2011 Aug;31(4):584-7. Epub 2011 Apr 21.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1007/s10875-011-9535-5

[Tracheobronchial involvement in Wegener's granulomatosis.]

PMID: 21450317
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Jul 23;137(5):230-5. Epub 2011 Mar 29.
Impact factor:
Publication type: Editorial in national publication
Authors: ; ; et al.
DOI: 10.1016/j.medcli.2011.01.007

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort.

PMID: 21187296
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2011
Reference: Ann Rheum Dis. 2011 Apr;70(4):638-41. Epub 2010 Dec 27.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1136/ard.2010.141838

Efficacy of Cyclophospamide in the Treatment of Interstitial Lung Disease Associated with Systemic Sclerosis.

PMID: 21458128
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2011
Reference: Arch Bronconeumol. 2011 May;47(5):239-45. Epub 2011 Mar 31.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.arbres.2011.01.010

Autoimmune diseases induced by biological agents: a double-edged sword?

PMID: 19854301
Journal: AUTOIMMUNITY REVIEWS
Year: 2010
Reference: Autoimmun Rev. 2010 Jan;9(3):188-93. Epub 2009 Oct 23.
Impact factor:
Publication type: Paper in international publication
Authors: ; Ayala, M M; Brito-Zeron, P; Callejas, J L; Caminal-Montero, L; Camps, M T; Colodro, A; Cuadrado, Maria-Jose; de Ramon, E; Diaz-Lagares, C et al.
DOI: 10.1016/j.autrev.2009.10.003

Age-related survival and clinical features in systemic sclerosis patients older or younger than 65 at diagnosis.

PMID: 20223816
Journal: RHEUMATOLOGY
Year: 2010
Reference: Rheumatology (Oxford). 2010 Jun;49(6):1112-7. doi: 10.1093/rheumatology/keq046. Epub 2010 Mar 11.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1093/rheumatology/keq046

Preliminary cross-cultural adaptation of a new pediatric health-related quality of life scale in children with systemic lupus erythematosus: an international effort.

PMID: 19934176
Journal: LUPUS
Year: 2010
Reference: Lupus. 2010 Jan;19(1):83-8. Epub 2009 Nov 24.
Impact factor:
Publication type: Paper in international publication
Authors: Adams, A; Adcock, K G; Akdeniz, D; Almeida de Jesus, A; Anton, J; Avcin, T; Bader-Meunier, B; Baratelli, M J; Barillas-Arias, L; Barinstein, L et al.
DOI: 10.1177/0961203309345770

[Home intravenous antibiotic therapy of hepatic abscess: Safety, efficacy and predictive factor of hospital readmission.]

PMID: 20202654
Journal: MEDICINA CLINICA
Year: 2010
Reference: Med Clin (Barc). 2010 Apr 17;134(11):473-6. Epub 2010 Mar 4.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; et al.
DOI: 10.1016/j.medcli.2009.10.050

Circulating microparticles, lupus anticoagulant and recurrent miscarriages.

PMID: 19410360
Journal: EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Year: 2009
Reference: Eur J Obstet Gynecol Reprod Biol. 2009 Jul;145(1):22-6.
Impact factor:
Publication type: Review in national publication
Authors: Alijotas-Reig, Jaume; Palacio-Garcia, Carles; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.ejogrb.2009.04.002

Late-Onset Immune-Mediated Adverse Effects after Poly-L-Lactic Acid Injection in Non-HIV Patients: Clinical Findings and Long-Term Follow-Up.

PMID: 19797889
Journal: DERMATOLOGY
Year: 2009
Reference: Dermatology. 2009;219(4):303-8.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; et al.
DOI: 10.1159/000243804

[Neuropsyquiatric manifestations in systemic lupus erythematosus]

PMID: 19442996
Journal: MEDICINA CLINICA
Year: 2009
Reference: Med Clin (Barc). 2009 May 30;132(20):797-801.
Impact factor:
Publication type: Paper in national publication
Authors: Martinez Valle, Fernando; Ordi-Ros, Josep; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.medcli.2009.02.045

Livedo racemosa as a marker of increased risk of recurrent thrombosis in patients with negative anti-phospholipid antibodies.

PMID: 19403146
Journal: MEDICINA CLINICA
Year: 2009
Reference: Med Clin (Barc). 2009 May 30;132(20):767-71.
Impact factor:
Publication type: Paper in national publication
Authors: Balada, Eva; Martinez-Valle, Ferran; Ordi-Ros, Josep; Selva-O'Callaghan, Albert; Solans-Laque, Roser; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.medcli.2008.09.044

Blog

News

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.