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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Team

Jaume Mestre Torres

Jaume Mestre Torres

Predoctoral researcher
Systemic Diseases
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Joan Lima Ruiz

Joan Lima Ruiz

Systemic Diseases
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Joan Rey Cano

Joan Rey Cano

Research technician
Systemic Diseases
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Joana Rita Marques Soares

Joana Rita Marques Soares

Predoctoral researcher
Systemic Diseases
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José Manuel Rodríguez Moreno

José Manuel Rodríguez Moreno

Systemic Diseases
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Mari Carmen Pérez Bocanegra

Mari Carmen Pérez Bocanegra

Systemic Diseases
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Jaume Mestre Torres

Jaume Mestre Torres

Predoctoral researcher
Systemic Diseases
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Joan Lima Ruiz

Joan Lima Ruiz

Systemic Diseases
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Joan Rey Cano

Joan Rey Cano

Research technician
Systemic Diseases
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Joana Rita Marques Soares

Joana Rita Marques Soares

Predoctoral researcher
Systemic Diseases
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José Manuel Rodríguez Moreno

José Manuel Rodríguez Moreno

Systemic Diseases
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Mari Carmen Pérez Bocanegra

Mari Carmen Pérez Bocanegra

Systemic Diseases
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Research lines

Infection and Autoimmunity: relevance of Human Endogenous Retrovirus (HERV) in Systemic Lupus Erythematosus (SLE).

Antibodies against HERVs have been detected in patients suffering from some autoimmune diseases such as SLE, rheumatoid arthritis, Sjögren's syndrome, and multiple sclerosis. We mainly focus our research on trying to detect these antibodies in our patients affected with SLE. We have recently cloned some recombinant proteins specific for HERVs. We are simultaneously evaluating the transcription levels of several HERV proteins in T CD4+ lymphocytes from SLE patients.

IP: -

International Classification Criteria project for neuro-Behçet disease.

We are currently enrolled in this multicentre study coordinated by Dr. Seema Kalra from University Hospital of North Staffordshire (UK). The study aims to define new diagnostic criteria for neuro-Behçet disease. A set of neurologists, rheumatologists and specialists in Internal Medicine from different countries, experts in the diagnosis and management of this disease, will try to define a new set of diagnostic criteria based on clinical expertise, and in the most new laboratory and radiology modern tests.

IP: Roser Solans Laque

International Classification Criteria Project.

This is a multicentric study aimed at defining new diagnosis criteria for muscular inflammatory diseases. Although criteria given by Bohan and Peter are still used in clinical practice, some inflammatory diseases such as inclusion body myositis are not included. The hytopathological classification performed by Dalakas includes the latter entity but it does not take into account neither the paraneoplastic myositis nor those associated to systemic diseases.

IP: Albert Selva O'Callaghan

Lung involvement in inflammatory myopathies.

With this study we want to study the natural history of this syndrome mediated by anti-synthetase antibodies, the characterization of new antibodies that may be used as markers for lung involvement, as well as we aim at understanding better the etiopathogenicity and the treatment of this organic illness in patients with myositis.

IP: Albert Selva O'Callaghan

Publications

Ocular involvement in adult and paediatric patients with monogenic autoinflammatory diseases: a Spanish multicentre retrospective study.

PMID: 37812477
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2023
Reference: Clin Exp Rheumatol. 2023 Sep 28. doi: 10.55563/clinexprheumatol/ukegcc.
Impact factor:
Publication type: Paper in international publication
Authors: Adan, Alfredo; Anton, Jordi; Araujo, Olga; Artaraz, Joseba; Blanco, Ricardo; Bujan-Rivas, Segundo; Cantarini, Luca; Carreno, Ester; Cocho, Lidia; Distefano, Laura et al.
DOI: 10.55563/clinexprheumatol/ukegcc

Changes in echocardiographic parameters over time in paradoxical low-flow low-gradient aortic stenosis.

PMID: 37131301
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2023
Reference: Eur Heart J Cardiovasc Imaging. 2023 May 3:jead067. doi: 10.1093/ehjci/jead067.
Impact factor:
Publication type: Paper in international publication
Authors: Arnau Vives, Miguel Angel; Aviles, Augusto Sao; Bouzas, Alberto; Calvo, Francisco; Casas, Guillem; Dux-Santoy, Lydia; Evangelista, Artur; Fernandez-Galera, Ruben; Ferreira-Gonzalez, Ignacio; Ferrer-Sistach, Elena et al.
DOI: 10.1093/ehjci/jead067

Changes in vascular access profile for pediatric hemodialysis patients over time: A registry-based study from Catalonia.

PMID: 37817674
Journal: Journal of Vascular Access
Year: 2023
Reference: J Vasc Access. 2023 Oct 11:11297298231202634. doi: 10.1177/11297298231202634.
Impact factor:
Publication type: Paper in international publication
Authors: Ariceta, Gema; Cardona, Victoria; Comas, Jordi; Cruz, Alejandro; Dolle-Bierke, Sabine; Ensina, Luis Felipe; Francuzik, Wojciech; Hartmann, Karin; Hofer, Veronika; Moeser, Anne et al.
DOI: 10.1177/11297298231202634

Anaphylaxis.

PMID: 37833106
Journal: MEDICINA CLINICA
Year: 2023
Reference: Med Clin (Barc). 2023 Oct 11:S0025-7753(23)00552-3. doi: 10.1016/j.medcli.2023.08.010.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Andrade, Fernanda; Cardona, Victoria; Duran-Lara, Esteban F; Galvan-Blasco, Paula; Gil-Serrano, Johana; Lobos G, Olga; Rafael, Diana; Vijayakumar, Sekar et al.
DOI: 10.1016/j.medcli.2023.08.010

Recommendations by the Spanish Society of Rheumatology on the management of patients with fibromyalgia. Part II.

PMID: 34538611
Journal: Reumatologia clinica
Year: 2022
Reference: Reumatol Clin. 2022 May;18(5):260-265. doi: 10.1016/j.reumae.2021.01.005. Epub 2021 Sep 15.
Impact factor: 0
Publication type: Paper in national publication
Authors: Trillo Calvo, Eva, Rivera Redondo, Javier, Diaz Del Campo Fontecha, Petra, Alegre de Miquel, Cayetano, Almirall Bernabe, Miriam, Casanueva Fernandez, Benigno, Castillo Ojeda, Cristina, Collado Cruz, Antonio, Monteso-Curto, Pilar, Palao Tarrero, Angela et al.
DOI: 10.1016/j.reuma.2021.01.006

Retention of subcutaneous abatacept for the treatment of rheumatoid arthritis: real-world results from the ASCORE study: an international 2-year observational study.

PMID: 35536413
Journal: CLINICAL RHEUMATOLOGY
Year: 2022
Reference: Clin Rheumatol. 2022 Aug;41(8):2361-2373. doi: 10.1007/s10067-022-06176-1. Epub 2022 May 10.
Impact factor: 2.98
Publication type: Paper in international publication
Authors: Patel, Yusuf, Marsal, Sara, Sanmarti, Raimon, Nurmohamed, Michael T, Griffiths, Hedley, Peichl, Peter, Bannert, Bettina, Chartier, Melanie, Connolly, Sean E, Lozenski, Karissa et al.
DOI: 10.1007/s10067-022-06176-1

Clinical features and outcomes of COVID-19 in patients with IgG4-related disease: a European multi-center study.

PMID: 34919665
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 May 5;61(5):e109-e111. doi: 10.1093/rheumatology/keab930.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Schleinitz, Nicolas, Martinez-Valle, Fernando, Culver, Emma L, Della-Torre, Emanuel, Dagna, Lorenzo, Orozco-Galvez, Olimpia, Fernandez-Codina, Andreu, Ramirez, Giuseppe A, Lanzillotta, Marco, Ebbo, Mikael et al.
DOI: 10.1093/rheumatology/keab930

Consensus on the definition of disease control and response assessment in chronic urticaria.

PMID: 35503509
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Investig Allergol Clin Immunol. 2022 May 2:0. doi: 10.18176/jiaci.0820.
Impact factor: 7.033
Publication type: Review in international publication
Authors: Gimenez-Arnau, A M, Jauregui, I, Silvestre-Salvador, J F, Valero, A, Ferrer, M, Sastre, J, Ortiz de Frutos, F J, Labrador-Horrillo, M, Bartra, J, Miquel Miquel, J et al.
DOI: 10.18176/jiaci.0820

[World Allergy Organization Anaphylaxis Guidance 2020].

PMID: 34759087
Journal: Japanese Journal of Allergology
Year: 2021
Reference: Arerugi. 2021;70(9):1211-1234. doi: 10.15036/arerugi.70.1211.
Impact factor: 0
Publication type: Paper in international publication
Authors: Worm, Margitta, Thong, Bernard Y, Cardona, Victoria, Ansotegui, Ignacio J, Ebisawa, Motohiro, El-Gamal, Yehia, Rivas, Montserrat Fernandez, Fineman, Stanley, Geller, Mario, Gonzalez-Estrada, Alexei et al.
DOI: 10.15036/arerugi.70.1211

Clinical features and health-related quality of life in adult patients with mucopolysaccharidosis IVA: the Spanish experience.

PMID: 34732228
Journal: Orphanet Journal of Rare Diseases
Year: 2021
Reference: Orphanet J Rare Dis. 2021 Nov 3;16(1):464. doi: 10.1186/s13023-021-02074-y.
Impact factor: 4.123
Publication type: Paper in international publication
Authors: Quijada-Fraile, Pilar, Arranz Canales, Elena, Martin-Hernandez, Elena, Ballesta-Martinez, Maria Juliana, Guillen-Navarro, Encarna, Pintos-Morell, Guillem, Molto-Abad, Marc, Moreno-Martinez, David, Garcia Morillo, Salvador, Blasco-Alonso, Javier et al.
DOI: 10.1186/s13023-021-02074-y

Pharmacologic Treatment of Anti-MDA5 Rapidly Progressive Interstitial Lung Disease.

PMID: 34603940
Journal: Current treatment options in rheumatology
Year: 2021
Reference: Curr Treatm Opt Rheumatol. 2021;7(4):319-333. doi: 10.1007/s40674-021-00186-x. Epub 2021 Sep 28.
Impact factor: 0
Publication type: Review in international publication
Authors: Sanchez-Pernaute, O, Pinal-Fernandez, I, Ruiz-Rodriguez, J C, Gil-Vila, A, Trallero-Araguas, E, Romero-Bueno, F, Selva-O'Callaghan, A et al.
DOI: 10.1007/s40674-021-00186-x

Trajectories in early rheumatoid arthritis related fatigue over 10 years: results from the ESPOIR cohort.

PMID: 34596027
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2021
Reference: Clin Exp Rheumatol. 2021 Sep 21. pii: 17302.
Impact factor: 4.473
Publication type: Paper in international publication
Authors: Rodriguez-Muguruza, Samantha, Combe, Bernard, Guillemin, Francis, Fautrel, Bruno, Olive, Alejandro, Marsal, Sara, Valero, Oliver, Lukas, Cedric et al.
DOI:

Tocilizumab in giant cell arteritis: differences between the GiACTA trial and a multicentre series of patients from the clinical practice.

PMID: 32441643
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2020
Reference: Clin Exp Rheumatol. 2020 Mar-Apr;38 Suppl 124(2):112-119. Epub 2020 May 21.
Impact factor: 3.319
Publication type: Paper in international publication
Authors: Calderon-Goercke, Monica, Castaneda, Santos, Aldasoro, Vicente, Villa, Ignacio, Prieto-Pena, Diana, Atienza-Mateo, Belen, Patino, Esther, Moriano, Clara, Romero-Yuste, Susana, Narvaez, Javier et al.
DOI:

Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis.

PMID: 32843099
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2020
Reference: Arthritis Res Ther. 2020 Aug 25;22(1):196. doi: 10.1186/s13075-020-02287-9.
Impact factor: 4.103
Publication type: Paper in international publication
Authors: Julia, Antonio, Avila, Gabriela, Celis, Raquel, Sanmarti, Raimon, Ramirez, Julio, Marsal, Sara, Canete, Juan D et al.
DOI: 10.1186/s13075-020-02287-9

Anti-HMGCR Specificity of HALIP: A Confirmatory Study.

PMID: 32766318
Journal: Journal of Immunology Research
Year: 2020
Reference: J Immunol Res. 2020 Jul 16;2020:6292631. doi: 10.1155/2020/6292631. eCollection 2020.
Impact factor: 3.327
Publication type: Paper in international publication
Authors: Baucells, Andres, Martinez, Maria Angeles, Alvarado-Cardenas, Marcelo, Mariscal, Anais, Martinez-Martinez, Laura, Juarez, Candido, Selva-O'Callaghan, Albert et al.
DOI: 10.1155/2020/6292631

Peripheral Corticotropin-Releasing Factor Triggers Jejunal Mast Cell Activation and Abdominal Pain in Patients With Diarrhea-Predominant Irritable Bowel Syndrome.

PMID: 32740086
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2020
Reference: Am J Gastroenterol. 2020 Dec;115(12):2047-2059. doi: 10.14309/ajg.0000000000000789.
Impact factor: 10.171
Publication type: Paper in international publication
Authors: Guilarte, Mar, Vicario, Maria, Martinez, Cristina, de Torres, Ines, Lobo, Beatriz, Pigrau, Marc, Gonzalez-Castro, Ana, Rodino-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina et al.
DOI: 10.14309/ajg.0000000000000789

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.

PMID: 31672989
Journal: Nature Communications
Year: 2019
Reference: Nat Commun. 2019 Oct 31;10(1):4955. doi: 10.1038/s41467-019-12760-y.
Impact factor: 11.878
Publication type: Paper in international publication
Authors: Rios, R, de Vries-Bouwstra, Jeska, Wijmenga, Cisca, Koeleman, Bobby P C, Nordin, Annika, Padyukov, Leonid, Hoffmann-Vold, Anna-Maria, Lie, Benedicte, Proudman, Susanna, Stevens, Wendy et al.
DOI: 10.1038/s41467-019-12760-y

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 2).

PMID: 31656683
Journal: Journal of Thoracic Disease
Year: 2019
Reference: J Thorac Dis. 2019 Sep;11(9):4072-4084. doi: 10.21037/jtd.2019.09.38.
Impact factor: 2.027
Publication type: Review in international publication
Authors: Williams, Sian, Pham-Thi, Nhan, Bedbrook, Anna, Agache, Ioana, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep M, Bachert, Claus, Benveniste, Samuel, Bewick, Mike et al.
DOI: 10.21037/jtd.2019.09.38

Malignancy and myositis, from molecular mimicry to tumor infiltrating lymphocytes.

PMID: 31635909
Journal: NEUROMUSCULAR DISORDERS
Year: 2019
Reference: Neuromuscul Disord. 2019 Nov;29(11):819-825. doi: 10.1016/j.nmd.2019.09.014. Epub 2019 Sep 26.
Impact factor: 2.612
Publication type: Review in international publication
Authors: Selva-O'Callaghan, Albert, Ros, Javier, Gil-Vila, Albert, Vila-Pijoan, Gemma, Trallero-Araguas, Ernesto, Pinal-Fernandez, Iago et al.
DOI: 10.1016/j.nmd.2019.09.014

Agreement between results of meta-analyses from case reports and clinical studies, regarding efficacy and safety of idursulfase therapy in patients with mucopolysaccharidosis type II (MPS-II). A new tool for evidence-based medicine in rare diseases.

PMID: 31639024
Journal: Orphanet Journal of Rare Diseases
Year: 2019
Reference: Orphanet J Rare Dis. 2019 Oct 21;14(1):230. doi: 10.1186/s13023-019-1202-6.
Impact factor: 3.687
Publication type: Paper in international publication
Authors: Sampayo-Cordero, Miguel, Miguel-Huguet, Bernat, Pardo-Mateos, Almudena, Malfettone, Andrea, Perez-Garcia, Jose, Llombart-Cussac, Antonio, Cortes, Javier, Molto-Abad, Marc, Munoz-Delgado, Cecilia, Perez-Quintana, Marta et al.
DOI: 10.1186/s13023-019-1202-6

Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure who reach complete response after rescue treatment.

PMID: 30129233
Journal: HEMATOLOGICAL ONCOLOGY
Year: 2018
Reference: Hematol Oncol. 2018 Dec;36(5):765-772. doi: 10.1002/hon.2553. Epub 2018 Sep 12.
Impact factor: 3.193
Publication type: Paper in international publication
Authors: Jarque, Isidro, Martinez-Sanchez, Pilar, Martin, Alejandro, Coria, Erika, Lopez-Guillermo, Armando, Salar, Antonio, Lahuerta, Juan Jose, Palomera, Luis, Magnano, Laura, Perez, Elena et al.
DOI: 10.1002/hon.2553

Dimensional Personality Assessment among a Chronic Fatigue Syndrome (CFS) sample with Personality Inventory for DSM-5 (PID-5).

PMID: 30079926
Journal: ACTAS ESPANOLAS DE PSIQUIATRIA
Year: 2018
Reference: Actas Esp Psiquiatr. 2018 Jul;46(4):125-32. Epub 2018 Jul 1.
Impact factor: 0.878
Publication type: Paper in national publication
Authors: Pueyo, Natalia, Gutierrez, Fernando, Ferrer, Marc, Castro-Marrero, Jesus, Alegre, Jose, Casas, Miquel, Ramos Quiroga, Josep-Antoni, Saez-Francas, Naia, Calvo, Natalia et al.
DOI:

Microbiome and Allergic Diseases.

PMID: 30065721
Journal: Frontiers in Immunology
Year: 2018
Reference: Front Immunol. 2018 Jul 17;9:1584. doi: 10.3389/fimmu.2018.01584. eCollection 2018.
Impact factor: 5.511
Publication type: Review in national publication
Authors: Mayorga, Cristobalina, Labrador, Moises, Zamorano, Miguel, Pascal, Mariona, Perez-Gordo, Marina, Caballero, Teresa, Escribese, Maria M, Lopez Longo, M Natividad, Luengo, Olga, Manso, Luis et al.
DOI: 10.3389/fimmu.2018.01584

Geolocation with respect to personal privacy for the Allergy Diary app - a MASK study.

PMID: 30061979
Journal: World Allergy Organization Journal
Year: 2018
Reference: World Allergy Organ J. 2018 Jul 16;11(1):15. doi: 10.1186/s40413-018-0194-3. eCollection 2018.
Impact factor: 5.676
Publication type: Paper in international publication
Authors: Onorato, G L, Samreth, D, Arnavielhe, S, Ingenrieth, F, Bedbrook, A, Almeida, R, Samolinski, B, Klimek, L, Mosges, R, Pfaar, O et al.
DOI: 10.1186/s40413-018-0194-3

New trends in anaphylaxis.

PMID: 29214141
Journal: Allergo journal international
Year: 2017
Reference: Allergo J Int. 2017;26(8):295-300. doi: 10.1007/s40629-017-0042-y. Epub 2017 Nov 15.
Impact factor: 0
Publication type: Review in national publication
Authors: Worm, Margitta, Sturm, Gunter, Kleine-Tebbe, Jorg, Cichocka-Jarosz, Ewa, Cardona, Victoria, Maris, Ioana, Dolle, Sabine et al.
DOI: 10.1007/s40629-017-0042-y

EULAR/ACR classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups: a methodology report.

PMID: 29177080
Journal: RMD open
Year: 2017
Reference: RMD Open. 2017 Nov 14;3(2):e000507. doi: 10.1136/rmdopen-2017-000507. eCollection 2017.
Impact factor: 0
Publication type: Paper in international publication
Authors: Danko, Katalin, Dimachkie, Mazen M, Feldman, Brian M, Garcia-De La Torre, Ignacio, Gordon, Patrick, Hayashi, Taichi, Katz, James D, Kohsaka, Hitoshi, Lachenbruch, Peter A, Lang, Bianca A et al.
DOI: 10.1136/rmdopen-2017-000507

2017 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and Their Major Subgroups.

PMID: 29106061
Journal: Arthritis & Rheumatology
Year: 2017
Reference: Arthritis Rheumatol. 2017 Dec;69(12):2271-2282. doi: 10.1002/art.40320. Epub 2017 Oct 27.
Impact factor: 6.918
Publication type: Paper in international publication
Authors: Bottai, Matteo, Lundberg, Ingrid E, Tjarnlund, Anna, Sanner, Helga, Selva-O'Callaghan, Albert, Song, Yeong-Wook, Vencovsky, Jiri, Ytterberg, Steven R, Miller, Frederick W, Rider, Lisa G et al.
DOI: 10.1002/art.40320

2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups.

PMID: 29079590
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2017
Reference: Ann Rheum Dis. 2017 Dec;76(12):1955-1964. doi: 10.1136/annrheumdis-2017-211468. Epub 2017 Oct 27.
Impact factor: 12.811
Publication type: Editorail in international publication
Authors: Sanner, Helga, Liang, Matthew H, Singh, Jasvinder A, Aggarwal, Rohit, Arnardottir, Snjolaug, Chinoy, Hector, Cooper, Robert G, Danko, Katalin, Dimachkie, Mazen M, Feldman, Brian M et al.
DOI: 10.1136/annrheumdis-2017-211468

Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children.

PMID: 27554814
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2016
Reference: J Allergy Clin Immunol. 2016 Dec;138(6):1752-1755. doi: 10.1016/j.jaci.2016.07.015. Epub 2016 Aug 20.
Impact factor: 12.485
Publication type: Letter whit IF
Authors: Fremond, Marie-Louise, Neven, Benedicte, Crow, Yanick Joseph, Rieux-Laucat, Frederic, Rodero, Mathieu Paul, Jeremiah, Nadia, Belot, Alexandre, Jeziorski, Eric, Duffy, Darragh, Bessis, Didier et al.
DOI: 10.1016/j.jaci.2016.07.015

Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway.

PMID: 26338038
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2016
Reference: Ann Rheum Dis. 2016 Aug;75(8):1521-6. doi: 10.1136/annrheumdis-2015-208154. Epub 2015 Sep 2.
Impact factor: 10.377
Publication type: Paper in international publication
Authors: Bellocchi, Chiara, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jorg Hw, Voskuyl, Alexandre E et al.
DOI: 10.1136/annrheumdis-2015-208154

[Study of prognostic factors and prevalence of post-thrombotic syndrome in Spain in patients with deep vein thrombosis].

PMID: 26198362
Journal: MEDICINA CLINICA
Year: 2016
Reference: Med Clin (Barc). 2016 Jan 15;146(2):49-54. doi: 10.1016/j.medcli.2015.04.030. Epub 2015 Jul 18.
Impact factor: 1.417
Publication type: Paper in national publication
Authors: Camacho, Isabel, Marin, Nuria, Acosta, Fernando, Salmeron, Luis, Ordi, Josep et al.
DOI: 10.1016/j.medcli.2015.04.030

Effect of coenzyme Q plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise testing in chronic fatigue syndrome - A randomized, controlled, double-blind trial.

PMID: 26212172
Journal: CLINICAL NUTRITION
Year: 2016
Reference: Clin Nutr. 2016 Aug;35(4):826-34. doi: 10.1016/j.clnu.2015.07.010. Epub 2015 Jul 17.
Impact factor: 4.476
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Saez-Francas, Naia, Segundo, Maria Jose, Calvo, Natalia, Faro, Monica, Aliste, Luisa, Fernandez de Sevilla, Tomas, Alegre, Jose et al.
DOI: 10.1016/j.clnu.2015.07.010

Management of urticaria: not too complicated, not too simple.

PMID: 25429900
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2015
Reference: Clin Exp Allergy. 2015 Apr;45(4):731-43. doi: 10.1111/cea.12465.
Impact factor: 4.324
Publication type: Paper in international publication
Authors: Ferrer, M, Bartra, J, Gimenez-Arnau, A, Jauregui, I, Labrador-Horrillo, M, Silvestre, Jf, Sastre, J, Velasco, M, Valero, A, de Frutos, J Ortiz et al.
DOI: 10.1111/cea.12465

[Fibromyalgia as a comorbid phenomenon in autoinflammatory diseases.]

PMID: 25433788
Journal: MEDICINA CLINICA
Year: 2015
Reference: Med Clin (Barc). 2015 Jun 8;144(11):525. doi: 10.1016/j.medcli.2014.07.033. Epub 2014 Nov 26.
Impact factor: 1.252
Publication type: Letter whit IF
Authors: Faro, Monica, Alegre, Jose et al.
DOI: 10.1016/j.medcli.2014.07.033

Inappropriate prescribing to the oldest old patients admitted to hospital: prevalence, most frequently used medicines, and associated factors.

PMID: 25887546
Journal: BMC Geriatrics
Year: 2015
Reference: BMC Geriatr. 2015 Apr 9;15:42. doi: 10.1186/s12877-015-0038-8.
Impact factor: 1.676
Publication type: Paper in international publication
Authors: Lopez-Soto, Alfonso, Ramirez-Duque, Nieves, Torres, Olga H, Barbe, Jose, San-Jose, Antonio, Agusti, Antonia, Vidal, Xavier, Aguilera, Cristina, Ballarin, Elena, Perez, Eulalia et al.
DOI: 10.1186/s12877-015-0038-8

[Anemia in elderly patients admitted to an acute geriatric ward].

PMID: 25749584
Journal: Revista espanola de geriatria y gerontologia
Year: 2015
Reference: Rev Esp Geriatr Gerontol. 2015 May-Jun;50(3):122-5. doi: 10.1016/j.regg.2014.09.002. Epub 2015 Mar 4.
Impact factor: 0
Publication type: Paper in national publication
Authors: San Jose-Laporte, Antonio, Barbe-Gil Ortega, Jose, Duran-Taberna, Montserrat, Romero-Ruperto, Sheila, Perez-Bocanegra, Maria Carmen, Toscano-Rivera, Ainhoa et al.
DOI: 10.1016/j.regg.2014.09.002

Health related quality of life measure in systemic pediatric rheumatic diseases and its translation to different languages: an international collaboration.

PMID: 25705138
Journal: PEDIATR RHEUMATOL
Year: 2014
Reference: Pediatr Rheumatol Online J. 2014 Nov 25;12:49. doi: 10.1186/1546-0096-12-49. eCollection 2014.
Impact factor: 1.622
Publication type: Paper in international publication
Authors: Hassett, Afton L, Lehman, Thomas J A, Scott, Christiaan, El-Ghoneimy, Dalia, Saad, Shereen, El Feky, Reem, Al-Mayouf, Sulaiman, Dolezalova, Pavla, Malcova, Hana, Herlin, Troels et al.
DOI: 10.1186/1546-0096-12-49

Anti-TNF-alpha therapy in patients with refractory uveitis due to Behcet's disease: a 1-year follow-up study of 124 patients.

PMID: 24996907
Journal: RHEUMATOLOGY
Year: 2014
Reference: Rheumatology (Oxford). 2014 Dec;53(12):2223-31. doi: 10.1093/rheumatology/keu266. Epub 2014 Jul 4.
Impact factor: 4.435
Publication type: Paper in international publication
Authors: Vazquez, Julio, Peiteado-Lopez, Diana, Pato, Esperanza, Cruz, Juan, Fernandez-Cid, Carlos, Aurrecoechea, Elena, Garcia, Miriam, Caracuel, Miguel A, Montilla, Carlos, Atanes, Antonio et al.
DOI: 10.1093/rheumatology/keu266

A genome-wide association study of anorexia nervosa.

PMID: 24514567
Journal: MOL PSYCHIATR
Year: 2014
Reference: Mol Psychiatry. 2014 Oct;19(10):1085-94. doi: 10.1038/mp.2013.187. Epub 2014 Feb 11.
Impact factor: 15.147
Publication type: Paper in international publication
Authors: Rajewski, A, Santonastaso, P, Fernandez-Aranda, F, Gratacos, M, Rybakowski, F, Dmitrzak-Weglarz, M, Kaprio, J, Keski-Rahkonen, A, Raevuori, A, Van Furth, E F et al.
DOI: 10.1038/mp.2013.187

The Pathogenesis and Genetics of Psoriasis.

PMID: 23369832
Journal: Actas dermo-sifiliograficas
Year: 2014
Reference: Actas Dermosifiliogr. 2014 Jul-Aug;105(6):535-45. doi: 10.1016/j.ad.2012.11.006. Epub 2013 Jan 29.
Impact factor: 0
Publication type: Review in national publication
Authors: Puig, L, Julia, A, Marsal, S et al.
DOI: 10.1016/j.ad.2012.11.006

Identification of thaumatin-like protein and aspartyl protease as new major allergens in lettuce (Lactuca sativa).

PMID: 23983075
Journal: MOLECULAR NUTRITION & FOOD RESEARCH
Year: 2013
Reference: Mol Nutr Food Res. 2013 Dec;57(12):2245-52. doi: 10.1002/mnfr.201300139. Epub 2013 Aug 25.
Impact factor: 4.31
Publication type: Paper in international publication
Authors: Labrador-Horrillo, Moises, Munoz-Garcia, Esther, Luengo-Sanchez, Olga, Haroun-Diaz, Elisa, Maroto, Aroa Sanz, Palacin, Arancha, Diaz-Perales, Araceli, de Las Heras Gozalo, Manuel, Pastor-Vargas, Carlos, Cuesta-Herranz, Javier et al.
DOI: 10.1002/mnfr.201300139

Efficacy of omalizumab in chronic spontaneous urticaria refractory to conventional therapy: analysis of 110 patients in real-life practice.

PMID: 23875845
Journal: EXPERT OPINION ON BIOLOGICAL THERAPY
Year: 2013
Reference: Expert Opin Biol Ther. 2013 Sep;13(9):1225-8. doi: 10.1517/14712598.2013.822484. Epub 2013 Jul 23.
Impact factor: 3.345
Publication type: Paper in international publication
Authors: Gimenez-Arnau, Ana, Ferrer, Marta, Ortiz de Frutos, Javier, Silvestre, Juan Francisco, Bartra, Joan, Sastre, Joaquin, Labrador-Horrillo, Moises, Valero, Antonio, Velasco, Manuel, Jauregui, Ignacio et al.
DOI: 10.1517/14712598.2013.822484

A 72 year-old man with dyspnea, circumferential aortic thickening and weight loss.

PMID: 23925898
Journal: ARTHRITIS CARE & RESEARCH
Year: 2013
Reference: Arthritis Care Res (Hoboken). 2013 Dec;65(12):2056-61. doi: 10.1002/acr.22100.
Impact factor: 3.731
Publication type: Paper in international publication
Authors: Arcos-Bertiz, Ibai Los, Santos-Ortega, Alba, Palomares, Jose Rodriguez, Juanos-Iborra, Montserrat, Bujan-Rivas, Segundo, Tornos-Mas, Pilar, Martinez-Valle, Fernando et al.
DOI: 10.1002/acr.22100

Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier.

PMID: 22637702
Journal: GUT
Year: 2013
Reference: Gut. 2013 Aug;62(8):1160-8. doi: 10.1136/gutjnl-2012-302093. Epub 2012 May 25.
Impact factor: 10.732
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/gutjnl-2012-302093

Systemic lupus erythematosus: genomics, mechanisms, and therapies.

PMID: 22844327
Journal: Clinical & Developmental Immunology
Year: 2012
Reference: Clin Dev Immunol. 2012;2012:926931. Epub 2012 Jul 16.
Impact factor: 1.838
Publication type: Editorail in international publication
Authors: Fernandez-Nebro, Antonio, Marsal, Sara, Chatham, Winn, Rahman, Anisur et al.
DOI: 10.1155/2012/926931

Development of a disease-specific quality of life questionnaire for adult patients with hereditary angioedema due to C1 inhibitor deficiency (HAE-QOL): Spanish multi-centre research project.

PMID: 22817696
Journal: Health and Quality of Life Outcomes
Year: 2012
Reference: Health Qual Life Outcomes. 2012 Jul 20;10:82. doi: 10.1186/1477-7525-10-82.
Impact factor: 2.112
Publication type: Paper in international publication
Authors: Prior, Nieves, Remor, Eduardo, Gomez-Traseira, Carmen, Lopez Serrano, Concepcion, Cabanas, Rosario, Contreras, Javier, Campos, Angel, Cardona, Victoria, Cimbollek, Stefan, Gonzalez-Quevedo, Teresa et al.
DOI: 10.1186/1477-7525-10-82

Risk Variants for Psoriasis Vulgaris in a Large Case-Control Collection and Association with Clinical Subphenotypes.

PMID: 22814393
Journal: HUMAN MOLECULAR GENETICS
Year: 2012
Reference: Hum Mol Genet. 2012 Oct 15;21(20):4549-57. Epub 2012 Jul 19.
Impact factor: 7.636
Publication type: Paper in international publication
Authors: Julia, Antonio, Tortosa, Raul, Hernanz, Jose Manuel, Canete, Juan D, Fonseca, Eduardo, Ferrandiz, Carlos, Unamuno, Pablo, Puig, Lluis, Marsal, Sara, Absher, Devin et al.
DOI: 10.1093/hmg/dds295

Churg-Strauss Syndrome: An evolving paradigm.

PMID: 22796280
Journal: AUTOIMMUNITY REVIEWS
Year: 2012
Reference: Autoimmun Rev. 2012 Dec;12(2):235-40. doi: 10.1016/j.autrev.2012.07.009. Epub 2012 Jul 13.
Impact factor: 6.624
Publication type: Review in international publication
Authors: , , et al.
DOI: 10.1016/j.autrev.2012.07.009

[Chronic fatigue syndrome: study of a consecutive series of 824 cases assessed in two specialized units.]

PMID: 21794854
Journal: REVISTA CLINICA ESPANOLA
Year: 2011
Reference: Rev Clin Esp. 2011 Sep;211(8):385-90. Epub 2011 Jul 27.
Impact factor: 0.762
Publication type: Paper in national publication
Authors: , , , , , et al.
DOI: 10.1016/j.rce.2011.02.013

Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy.

PMID: 21779181
Journal: PLoS Genetics
Year: 2011
Reference: PLoS Genet. 2011 Jul;7(7):e1002178. Epub 2011 Jul 14.
Impact factor: 9.543
Publication type: Paper in international publication
Authors: Hunzelmann, Nicolas, Gorlova, Olga, Martin, Jose-Ezequiel, Rueda, Blanca, Koeleman, Bobby P C, Ying, Jun, Teruel, Maria, Diaz-Gallo, Lina-Marcela, Broen, Jasper C, Vonk, Madelon C et al.
DOI: 10.1371/journal.pgen.1002178

Rates of and risk factors for severe infections in patients with systemic autoimmune diseases receiving biological agents off-label.

PMID: 21745378
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2011
Reference: Arthritis Res Ther. 2011 Jul 11;13(4):R112. doi: 10.1186/ar3397.
Impact factor: 4.357
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1186/ar3397

Risk, Predictors, and Clinical Characteristics of Lymphoma Development in Primary Sjogren's Syndrome.

PMID: 21665245
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2011
Reference: Semin Arthritis Rheum. 2011 Dec;41(3):415-23. Epub 2011 Jun 12.
Impact factor: 4.744
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1016/j.semarthrit.2011.04.006

Incidence and risk of hospitalisation due to shingles and chickenpox in patients with rheumatic diseases treated with TNF antagonists.

PMID: 20551153
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2010
Reference: Ann Rheum Dis. 2010 Oct;69(10):1751-5. Epub 2010 Jun 15.
Impact factor: 8.111
Publication type: Paper in international publication
Authors: Barcelo, Mireia, Cebrian, Laura, Montoro, Maria, Montesinos, Dolores, Perez-Pampin, Eva, Ortiz, Ana Maria, Anton, Fred, Zea, Antonio, Ruiz, Francisco Javier Manero, Beltran, Chesus et al.
DOI: 10.1136/ard.2009.125658

[Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome]

PMID: 20447621
Journal: REVISTA CLINICA ESPANOLA
Year: 2010
Reference: Rev Clin Esp. 2010 Jun;210(6):284-8. Epub 2010 May 5.
Impact factor: 0.584
Publication type: Paper in national publication
Authors: Alegre, J, Roses, J M, Javierre, C, Ruiz-Baques, A, Segundo, M J, de Sevilla, T Fernandez et al.
DOI: 10.1016/j.rce.2009.09.015

Conventional cancer screening versus PET/CT in dermatomyositis/polymyositis.

PMID: 20569766
Journal: AMERICAN JOURNAL OF MEDICINE
Year: 2010
Reference: Am J Med. 2010 Jun;123(6):558-62.
Impact factor: 4.466
Publication type: Paper in international publication
Authors: Selva-O'Callaghan, Albert, Grau, Josep M, Gamez-Cenzano, Cristina, Vidaller-Palacin, Antonio, Martinez-Gomez, Xavier, Trallero-Araguas, Ernesto, Andia-Navarro, Eduard, Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.amjmed.2009.11.012

Long-term outcomes--mycophenolate mofetil treatment for lupus nephritis with addition of tacrolimus for resistant cases.

PMID: 20538787
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2010
Reference: Nephrol Dial Transplant. 2010 Dec;25(12):3939-48. Epub 2010 Jun 10.
Impact factor: 3.306
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.1093/ndt/gfq322

DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features.

PMID: 19318394
Journal: LUPUS
Year: 2009
Reference: Lupus. 2009 Apr;18(5):418-23.
Impact factor: 2.244
Publication type: Paper in international publication
Authors: Vilardell-Tarres, M, Martinez-Valle, F, Balada, E, Ordi-Ros, J, Bujan-Rivas, S, Sellas-Fernandez, A et al.
DOI: 10.1177/0961203308098189

Delayed immune-mediated adverse effects related to polyacrylamide dermal fillers: clinical findings, management, and follow-up.

PMID: 19207326
Journal: DERMATOLOGIC SURGERY
Year: 2009
Reference: Dermatol Surg. 2009 Feb;35 Suppl 1:360-6.
Impact factor: 2.102
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume, Garcia-Gimenez, Victor, Miro-Mur, Francesc, Vilardell-Tarres, Miquel, Alijotas Reig, Jaume et al.
DOI: 10.1111/j.1524-4725.2008.01041.x

[Treatment of Raynaud's phenomenon]

PMID: 19268093
Journal: REVISTA CLINICA ESPANOLA
Year: 2009
Reference: Rev Clin Esp. 2009 Jan;209(1):21-4.
Impact factor: 0.734
Publication type: Paper in national publication
Authors: Fonollosa-Pla, V, Pilar Simeon-Aznar, C, Vilardell-Tarres, M et al.
DOI:

The interleukin 23 receptor gene does not confer risk to systemic sclerosis and is not associated with systemic sclerosis disease phenotype.

PMID: 18713787
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2009
Reference: Ann Rheum Dis. 2009 Feb;68(2):253-6.
Impact factor: 7.188
Publication type: Paper in international publication
Authors: Pros, A, Camps, M T, Gonzalez-Gay, M A, Martin, J, Radstake, T R D J, Garcia-Portales, R, Aguirre-Zamorano, M A, Coenen, M J H, Rueda, B, Broen, J et al.
DOI: 10.1136/ard.2008.096719

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