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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Research lines

Spanish Registry of patients with Systemic vasculitides (REVAS).

This is a multicentre study supported by the Systemic Autoimmune Diseases Group (GEAS) from the Spanish Internal Medicine Society (SEMI). The aim of the study is to describe the different clinical forms of presentation of these diseases, the response to the conventional treatment of the different subtypes of vasculitides, and the prognostic factors and survival in our country. This study includes 17 Hospitals from Spain with a cohort of 300 patients. We are the study coordinator Centre.

IP: Roser Solans Laque

Spanish Registry of Scleroderma patients (Systemic Autoimmune Diseases Group, Spanish Internal Medicine Association).

This multicentric study includes 14 hospitals with a cohort of 916 scleroderma patients. Its main goal consists in determining both the prognosis factors and the survival of these patients.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Specific Antinuclear antibodies of scleroderma as markers for different clinical patterns.

We want to establish the relationship between the presence of specific autoantibodies for scleroderma (anti-centromere, anti-topoisomerase 1, anti-polymerase III, anti-U3 RNP, Anti-Th/To, Anti-Pm/Scl, anti-Ku) with the different demographic and clinical features as well as with the disease prognosis.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Study of IFN-gamma/STAT and TGF-beta/SMAD pathways in lupus patients with skin involvement. Role in the evolution to fibrosis.

With this project we aim at studying the status of the IFN-gamma/STAT and the TGF-beta/Smad intracellular signal pathways in cutaneous biopsies of patients with lupus. We are now analyzing the expression of several molecules involved in these pathways to be able both to discern the main differences among the different types of cutaneous lupus and to interpret the residual fibrotic lesions observed in discoid lupus.

IP: José Ordi Ros

Publications

Anti-U11/U12 Antibodies as a Rare but Important Biomarker in Patients with Systemic Sclerosis: A Narrative Review.

PMID: 37046475
Journal: Diagnostics
Year: 2023
Reference: Diagnostics (Basel). 2023 Mar 27;13(7):1257. doi: 10.3390/diagnostics13071257.
Impact factor:
Publication type: Review in international publication
Authors: Bentow, Chelsea; Beretta, Lorenzo; Callejas-Moraga, Eduardo; Fonollosa-Pla, Vicent; Fritzler, Marvin J; Guillen-Del-Castillo, Alfredo; Mahler, Michael; Marin, Ana; Palterer, Boaz; Perurena-Prieto, Janire et al.
DOI: 10.3390/diagnostics13071257

Severe and refractory gastrointestinal toxicity due to immune checkpoint inhibitors: clinical experience in a tertiary referral hospital.

PMID: 37170542
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2023
Reference: Rev Esp Enferm Dig. 2023 May 12. doi: 10.17235/reed.2023.9436/2022.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Borruel, Natalia; Casellas, Francesc; Casellas, Francesc; Cespedes Martinez, Elena; Cespedes Martinez, Elena; Herrera-De Guise, Claudia; Herrera-De Guise, Claudia; Mayorga, Luis; Mayorga, Luis et al.
DOI: 10.17235/reed.2023.9436/2022

Evaluation of triple negative breast cancer with heterogeneous immune infiltration.

PMID: 37215143
Journal: Frontiers in Immunology
Year: 2023
Reference: Front Immunol. 2023 May 4;14:1149747. doi: 10.3389/fimmu.2023.1149747. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Arenas, Enrique Javier; Arribas, Joaquin; Bernado, Cristina; Bernado, Cristina; Cortes, Javier; Curigliano, Giuseppe; Esteve-Codina, Anna; Gonzalez, Jonatan; Gonzalez, Jonatan; Marti, Merce et al.
DOI: 10.3389/fimmu.2023.1149747

INMUNOCAT study: The impact of molecular diagnosis on immunotherapy prescription in pollen polysensitized patients from Catalonia.

PMID: 37227418
Journal: Clinical and Translational Allergy
Year: 2023
Reference: Clin Transl Allergy. 2023 May;13(5):e12246. doi: 10.1002/clt2.12246.
Impact factor:
Publication type: Paper in international publication
Authors: Asensio, O; Bartra, J; Belmonte, J; Bobolea, I; De Linares, C; Farrarons, L; Garriga-Baraut, Teresa; Labrador-Horrillo, Moises; Miquel, S; Moncin, M M San Miguel et al.
DOI: 10.1002/clt2.12246

Anti-FHL1 antibody: welcome to a novel autoantibody in myositis.

PMID: 35460231
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Oct 6;61(10):3887-3888. doi: 10.1093/rheumatology/keac252.
Impact factor:
Publication type: Paper in international publication
Authors: Sanz-Martinez, Maria Teresa; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1093/rheumatology/keac252

Antiphospholipid antibodies in women with recurrent embryo implantation failure: A systematic review and meta-analysis.

PMID: 35452853
Journal: AUTOIMMUNITY REVIEWS
Year: 2022
Reference: Autoimmun Rev. 2022 Jun;21(6):103101. doi: 10.1016/j.autrev.2022.103101. Epub 2022 Apr 20.
Impact factor:
Publication type: Review in international publication
Authors: Alijotas-Reig, Jaume; Anunciacion-Llunell, Ariadna; Jarne-Borras, Marina; Miro-Mur, Francesc et al.
DOI: 10.1016/j.autrev.2022.103101

Poly-L-Lysine-Based alphaGal-Glycoconjugates for Treating Anti-alphaGal IgE-Mediated Diseases.

PMID: 35432370
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Mar 31;13:873019. doi: 10.3389/fimmu.2022.873019. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Ricardo N; Bello-Gil, Daniel; Bovin, Nicolai; Ferrero-Alves, Yara; Garcia Figueroa, Blanca Esther; Garcia-Perez, Ana L; Labrador-Horrillo, Moises; Manez, Rafael; Olivera-Ardid, Sara; Tuzikov, Alexander et al.
DOI: 10.3389/fimmu.2022.873019

Effect of tocilizumab versus standard of care in adults hospitalized with moderate-severe COVID-19 pneumonia.

PMID: 34147248
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin (Barc). 2022 Apr 8;158(7):301-307. doi: 10.1016/j.medcli.2021.03.005. Epub 2021 May 6.
Impact factor:
Publication type: Paper in national publication
Authors: Berlana, David; Campany-Herrero, David; Cardona-Pascual, Ignacio; Martinez-Valle, Ferran; Montoro-Ronsano, Jose Bruno et al.
DOI: 10.1016/j.medcli.2021.03.005

PAGE Study: Summary of a study protocol to estimate the prevalence of severe asthma in Spain using big-data methods.

PMID: 31983679
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Investig Allergol Clin Immunol. 2021 Jul 26;31(4):308-315. doi: 10.18176/jiaci.0483. Epub 2020 Jan 23.
Impact factor:
Publication type: Paper in international publication
Authors: Almonacid Sanchez, C; Alvarez Gutierrez, F J; Banas Conejero, D; Cardona, V; Melero Moreno, C; Quirce Gancedo, S; Sanchez-Herrero, M G; Soriano, J B et al.
DOI: 10.18176/jiaci.0483

Clinical characteristics of COVID-19 in older adults. A retrospective study in long-term nursing homes in Catalonia.

PMID: 34297774
Journal: PLoS One
Year: 2021
Reference: PLoS One. 2021 Jul 23;16(7):e0255141. doi: 10.1371/journal.pone.0255141. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Almirante, Benito; Andreu, Antoni L; Campins, Magda; Garcia-Navarro, Jose Augusto; Lopez-Segui, Francesc; Meis-Pinheiro, Uxio; San-Jose, Antonio; Santaeugenia, Sebastia; Ussi, Anton; Walsh, Sandra et al.
DOI: 10.1371/journal.pone.0255141

Anaphylaxis Induced By Beer.

PMID: 32938573
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Investig Allergol Clin Immunol. 2021 Jul 26;31(4):334-336. doi: 10.18176/jiaci.0643. Epub 2020 Sep 15.
Impact factor:
Publication type: Paper in international publication
Authors: Basagana, M; Labrador-Horrillo, M; Lazo, C; Navarro, L; Pineda, F; Roger, A et al.
DOI: 10.18176/jiaci.0643

Myositis and myasteniform syndrome related to pembrolizumab.

PMID: 34290006
Journal: BMJ case reports
Year: 2021
Reference: BMJ Case Rep. 2021 Jul 21;14(7). pii: 14/7/e241766. doi: 10.1136/bcr-2021-241766.
Impact factor:
Publication type: Letter or abstract
Authors: Montoro, Bruno; Ros, Javier; Ros, Javier; Sanchez-Sancho, Pablo; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1136/bcr-2021-241766

Covid-19 and autoimmunity.

PMID: 32535093
Journal: AUTOIMMUNITY REVIEWS
Year: 2020
Reference: Autoimmun Rev. 2020 Aug;19(8):102597. doi: 10.1016/j.autrev.2020.102597. Epub 2020 Jun 11.
Impact factor:
Publication type: Review in international publication
Authors: Alijotas-Reig, Jaume; Amital, Howard; Andreoli, Laura; Cattalini, Marco; Ehrenfeld, Michael; Greenbaum, Assaf; Kanduc, Darja; Semenova, Natalia; Shoenfeld, Yehuda; Tincani, Angela et al.
DOI: 10.1016/j.autrev.2020.102597

Recommendations for the treatment of anti-melanoma differentiation-associated gene 5-positive dermatomyositis-associated rapidly progressive interstitial lung disease.

PMID: 32534273
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2020
Reference: Semin Arthritis Rheum. 2020 Aug;50(4):776-790. doi: 10.1016/j.semarthrit.2020.03.007. Epub 2020 Jun 1.
Impact factor:
Publication type: Paper in international publication
Authors: Castellvi, I; Diaz Del Campo, P; Gono, T; Gonzalez-Gay, M A; Martinez-Becerra, M J; Pinal-Fernandez, I; Plana, M N; Rodriguez-Nieto, M J; Romero-Bueno, F; Ruiz-Rodriguez, J C et al.
DOI: 10.1016/j.semarthrit.2020.03.007

Tigecycline-associated hypofibrinogenemia in a real-world setting.

PMID: 32504166
Journal: International Journal of Clinical Pharmacy
Year: 2020
Reference: Int J Clin Pharm. 2020 Aug;42(4):1184-1189. doi: 10.1007/s11096-020-01072-7. Epub 2020 Jun 5.
Impact factor:
Publication type: Paper in international publication
Authors: Campany-Herrero, David; Espinosa-Pereiro, Juan; Lalueza-Broto, Pilar; Larrosa-Garcia, Maria; Mestre-Torres, Jaume; Pigrau-Serrallach, Carles; Rivera-Sanchez, Lucas et al.
DOI: 10.1007/s11096-020-01072-7

Is diet partly responsible for differences in COVID-19 death rates between and within countries?

PMID: 32499909
Journal: Clinical and Translational Allergy
Year: 2020
Reference: Clin Transl Allergy. 2020 May 27;10:16. doi: 10.1186/s13601-020-00323-0. eCollection 2020.
Impact factor:
Publication type: Review in international publication
Authors: Abdul Latiff, Amir Hamzah; Abdullah, Baharudin; Aberer, Werner; Abusada, Nancy; Adcock, Ian; Afani, Alejandro; Agache, Ioana; Aggelidis, Xenofon; Agustin, Jenifer; Akdis, Cezmi et al.
DOI: 10.1186/s13601-020-00323-0

Clinical characteristics and genetic analyses of 187 patients with undefined autoinflammatory diseases.

PMID: 31278138
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2019
Reference: Ann Rheum Dis. 2019 Oct;78(10):1405-1411. doi: 10.1136/annrheumdis-2018-214472. Epub 2019 Jul 5.
Impact factor:
Publication type: Paper in international publication
Authors: Brogan, Paul A; Cantarini, Luca; Cimaz, Rolando; Eijkelboom, Charlotte; Fingerhutova, Sarka; Frenkel, Joost; Gattorno, Marco; Hofer, Michael; Iagaru, Nicolae; Insalaco, Antonella et al.
DOI: 10.1136/annrheumdis-2018-214472

Correlation of fatigue with other disease related and psychosocial factors in patients with rheumatoid arthritis treated with tocilizumab: ACT-AXIS study.

PMID: 31261500
Journal: MEDICINE
Year: 2019
Reference: Medicine (Baltimore). 2019 Jun;98(26):e15947. doi: 10.1097/MD.0000000000015947.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Cayetano; Alvarez, Ceferino Barbazan; Ares, Laura Losada; Corominas, Hector; Dalmau-Carola, Joan; Ercole, Liliana; Fernandez-Cid, Carlos Marras; Gomez, Manuel Rodriguez; Gomez-Centeno, Antoni; Gonzalez-Albo, Silvia Paredes et al.
DOI: 10.1097/MD.0000000000015947

Sporadic inclusion body myositis: Diagnostic value of p62 immunostaining.

PMID: 31253480
Journal: MEDICINA CLINICA
Year: 2019
Reference: Med Clin (Barc). 2019 Dec 13;153(11):437-440. doi: 10.1016/j.medcli.2019.04.022. Epub 2019 Jun 26.
Impact factor:
Publication type: Paper in national publication
Authors: Garcia, Ana Matas; Grau, Josep Maria; Jou, Cristina; Milisenda, Jose C; O'Callaghan, Albert Selva; Pinal-Fernandez, Iago et al.
DOI: 10.1016/j.medcli.2019.04.022

Changing the history of anaphylaxis mortality statistics through the World Health Organization's International Classification of Diseases-11.

PMID: 31229269
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2019
Reference: J Allergy Clin Immunol. 2019 Sep;144(3):627-633. doi: 10.1016/j.jaci.2019.05.013. Epub 2019 Jun 20.
Impact factor:
Publication type: Review in international publication
Authors: Agache, Ioana; Annesi-Maesano, Isabella; Ansontegui, Ignacio; Bierrenbach, Ana Luiza; Cardona, Victoria; Casale, Thomas; Chalmers, Robert; Demoly, Pascal; Ebisawa, Motohiro; Gomez, Maximiliano et al.
DOI: 10.1016/j.jaci.2019.05.013

Diagnostic delay in acquired haemophilia: Analysis of causes and consequences in a 20-year Spanish cohort.

PMID: 29732654
Journal: HAEMOPHILIA
Year: 2018
Reference: Haemophilia. 2018 May;24(3):e163-e166. doi: 10.1111/hae.13499. Epub 2018 May 6.
Impact factor:
Publication type: Review in international publication
Authors: Altisent, C; Cortina, V; Fernandez-Diaz, N; Pardos-Gea, J; Parra, R et al.
DOI: 10.1111/hae.13499

Utility of the (18)F-Florbetapir positron emission tomography in systemic amyloidosis.

PMID: 29706127
Journal: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
Year: 2018
Reference: Amyloid. 2018 Jun;25(2):109-114. doi: 10.1080/13506129.2018.1467313. Epub 2018 Apr 28.
Impact factor:
Publication type: Paper in international publication
Authors: Bujan-Rivas, Segundo; Castell-Conesa, Joan; Cuberas-Borros, Gemma; Fernandez-Codina, Andreu; Gironella, Mercedes; Lorenzo-Bosquet, Carles; Martinez-Valle, Fernando; Mestre-Torres, Jaume; Solans-Laque, Roser et al.
DOI: 10.1080/13506129.2018.1467313

Critical view of anaphylaxis epidemiology: open questions and new perspectives.

PMID: 29632547
Journal: Allergy Asthma and Clinical Immunology
Year: 2018
Reference: Allergy Asthma Clin Immunol. 2018 Apr 4;14:12. doi: 10.1186/s13223-018-0234-0. eCollection 2018.
Impact factor:
Publication type: Review in national publication
Authors: Bierrenbach, Ana Luiza; Calderon, Moises A; Cardona, Victoria; Casale, Thomas; Chang, Yoon-Seok; Demoly, Pascal; Molinari, Nicolas; Papadopoulos, Nikolaos G; Simons, F Estelle R; Tanno, Luciana Kase et al.
DOI: 10.1186/s13223-018-0234-0

S100A12 and S100A8/9 proteins are biomarkers of articular disease activity in Blau syndrome.

PMID: 29635517
Journal: RHEUMATOLOGY
Year: 2018
Reference: Rheumatology. 2018 Jul 1;57(7):1299-304. doi: 10.1093/rheumatology/key090.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Jordi; Bader-Meunier, Brigitte; Bertin, John; Brissaud, Philippe; Chedeville, Gaelle; Cimaz, Rolando; Fernandez-Martin, Jorge; Foley, Kevin P; Guly, Catherine; Hachulla, Eric et al.
DOI: 10.1093/rheumatology/key090

[Management of anaphylaxis in Latin America: current situation].

PMID: 28658725
Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexi
Year: 2017
Reference: Rev Alerg Mex. 2017 Apr-Jun;64(2):171-177.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez-Perea, Alberto; Ansotegui, Ignacio J; Arias-Cruz, Alfredo; Cardona, Victoria; Gonzalez-Diaz, Sandra Nora; Ivancevich, Juan Carlos; Latour-Staffeld, Patricia; Sanchez-Borges, Mario; Serrano, Carlos; Sole, Dirceu et al.
DOI:

High sensitivity and negative predictive value of the DETECT algorithm for an early diagnosis of pulmonary arterial hypertension in systemic sclerosis: application in a single center.

PMID: 28615037
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2017
Reference: Arthritis Res Ther. 2017 Jun 14;19(1):135. doi: 10.1186/s13075-017-1327-8.
Impact factor:
Publication type: Paper in international publication
Authors: Berastegui, Cristina; Callejas-Moraga, Eduardo L; Domingo, Enric; Fonollosa-Pla, Vicente; Garcia, Gabriela; Guillen-Del Castillo, Alfredo; Lopez-Meseguer, Manuel; Rodriguez-Palomares, Jose F; Roman, Antonio; Simeon-Aznar, Carmen Pilar et al.
DOI: 10.1186/s13075-017-1327-8

Prognostic Role of Exhaled Breath Condensate pH and Fraction Exhaled Nitric Oxide in Systemic Sclerosis Related Interstitial Lung Disease.

PMID: 28038794
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2017
Reference: Arch Bronconeumol. 2017 Mar;53(3):120-127. doi: 10.1016/j.arbres.2016.09.014. Epub 2016 Dec 27.
Impact factor:
Publication type: Paper in national publication
Authors: Cruz, Maria J; Fonollosa-Pla, Vicente; Guillen-Del Castillo, Alfredo; Munoz, Xavier; Sanchez-Vidaurre, Sara; Simeon-Aznar, Carmen P et al.
DOI: 10.1016/j.arbres.2016.09.014

Comorbidity in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Nationwide Population-Based Cohort Study.

PMID: 28596045
Journal: PSYCHOSOMATICS
Year: 2017
Reference: Psychosomatics. 2017 Sep - Oct;58(5):533-543. doi: 10.1016/j.psym.2017.04.010. Epub 2017 Apr 21.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Aliste, Luisa; Calvo, Natalia; Castro-Marrero, Jesus; de Sevilla, Tomas Fernandez; Faro, Monica; Martinez-Martinez, Alba; Saez-Francas, Naia et al.
DOI: 10.1016/j.psym.2017.04.010

Unexplained Recurrent Miscarriage and Recurrent Implantation Failure: Is There a Place for Immunomodulation?

PMID: 26847715
Journal: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Year: 2016
Reference: Am J Reprod Immunol. 2016 Jul;76(1):8-28. doi: 10.1111/aji.12493. Epub 2016 Feb 5.
Impact factor:
Publication type: Review in national publication
Authors: Alijotas-Reig, Jaume; Bornes, Marie; Carbillon, Lionel; Cohen, Jonathan; Darai, Emile; Fain, Olivier; Kayem, Gilles; Mekinian, Arsene; Nicaise-Roland, Pascale et al.
DOI: 10.1111/aji.12493

A 40-Year-Old Woman With Back Pain.

PMID: 27938773
Journal: CHEST
Year: 2016
Reference: Chest. 2016 Dec;150(6):e159-e165. doi: 10.1016/j.chest.2016.08.1449.
Impact factor:
Publication type: Paper in international publication
Authors: Aranda-Rodriguez, Santiago; Bujan-Rivas, Segundo; Deu-Martin, Maria; Fernandez-Codina, Andreu; Parra-Farinas, Carmen; Romagosa, Cleofe et al.
DOI: 10.1016/j.chest.2016.08.1449

Statin-associated autoimmune myopathy: A distinct new IFL pattern can increase the rate of HMGCR antibody detection by clinical laboratories.

PMID: 27640317
Journal: AUTOIMMUNITY REVIEWS
Year: 2016
Reference: Autoimmun Rev. 2016 Dec;15(12):1161-1166. doi: 10.1016/j.autrev.2016.09.005. Epub 2016 Sep 15.
Impact factor:
Publication type: Paper in international publication
Authors: Acebes, E Martinez; Alvarado-Cardenas, M; Balada, E; Casademont, J; Gonzalez-Mera, L; Grau-Junyent, J M; Juarez, C; Labrador-Horrillo, M; Marin, A; Martinez, L et al.
DOI: 10.1016/j.autrev.2016.09.005

Urine metabolome profiling of immune-mediated inflammatory diseases.

PMID: 27609333
Journal: BMC Medicine
Year: 2016
Reference: BMC Med. 2016 Sep 8;14(1):133. doi: 10.1186/s12916-016-0681-8.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre-Zamorano, MariaAngeles; Alonso, Arnald; Alperi-Lopez, Mercedes; Andreu, JoseLuis; Avila, Gabriela; Barreiro-de Acosta, Manuel; Beltran, Antoni; Blanco, Francisco; Blanco, Ricardo; Canete, Juan D et al.
DOI: 10.1186/s12916-016-0681-8

Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis.

PMID: 26336855
Journal: ARTHRITIS RES THER
Year: 2015
Reference: Arthritis Res Ther. 2015 Sep 4;17:242. doi: 10.1186/s13075-015-0737-8.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Alonso, Arnald; Alperi-Lopez, Mercedes; Avila, Gabriela; Blanco, Francisco J; Canete, Juan D; Corominas, Hector; Erra, Alba; Fernandez-Gutierrez, Benjamin; Gonzalez-Alvaro, Isidoro et al.
DOI: 10.1186/s13075-015-0737-8

Assessment of amyloid deposits by F-florbetapir positron emission tomography.

PMID: 26081942
Journal: EUR J NUCL MED MOL I
Year: 2015
Reference: Eur J Nucl Med Mol Imaging. 2015 Oct;42(11):1778-1779. doi: 10.1007/s00259-015-3108-4. Epub 2015 Jun 17.
Impact factor:
Publication type: Paper in international publication
Authors: Gironella, Mercedes; Lorenzo-Bosquet, Carles; Martinez-Valle, Fernando; Riveiro-Barciela, Mar et al.
DOI: 10.1007/s00259-015-3108-4

More on remission of recalcitrant dermatomyositis treated with ruxolitinib.

PMID: 25806935
Journal: NEW ENGL J MED
Year: 2015
Reference: N Engl J Med. 2015 Mar 26;372(13):1273-4. doi: 10.1056/NEJMc1500688#SA1.
Impact factor:
Publication type: Letter whit IF
Authors: Labrador-Horrillo, Moises; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1056/NEJMc1500688#SA1

Treatment of ACEI-related angioedema with icatibant: a case series.

PMID: 25666515
Journal: INTERN EMERG MED
Year: 2015
Reference: Intern Emerg Med. 2015 Apr;10(3):345-50. doi: 10.1007/s11739-015-1205-9. Epub 2015 Feb 10.
Impact factor:
Publication type: Paper in international publication
Authors: Borrelli, Paolo; Bova, Maria; Guilarte, Mar; Rizzelli, Grazia Maria Luisa; Sala-Cunill, Anna; Zanichelli, Andrea et al.
DOI: 10.1007/s11739-015-1205-9

Systemic sclerosis, breast cancer and calcium channel blockers: A new player on the scene?

PMID: 24699394
Journal: AUTOIMMUNITY REVIEWS
Year: 2014
Reference: Autoimmun Rev. 2014 Aug;13(8):880-1. doi: 10.1016/j.autrev.2014.03.003. Epub 2014 Apr 1.
Impact factor:
Publication type: Letter whit IF
Authors: Bernal-Bello, D; Fonollosa-Pla, V; Garcia de Tena, J; Simeon-Aznar, C et al.
DOI: 10.1016/j.autrev.2014.03.003

Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study.

PMID: 25008944
Journal: THROMBOSIS AND HAEMOSTASIS
Year: 2014
Reference: Thromb Haemost. 2014 Oct;112(4):727-35. doi: 10.1160/TH14-03-0191. Epub 2014 Jul 10.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, J; Andreoli, L; Bertero, M T; Bremme, K; Brucato, A; Canti, V; Caramaschi, P; De Carolis, S; Del Ross, T; Di Poi, E et al.
DOI: 10.1160/TH14-03-0191

[Antiphospholipid syndrome registry.]

PMID: 24361153
Journal: MEDICINA CLINICA
Year: 2014
Reference: Med Clin (Barc). 2014 Jul 22;143(2):93. doi: 10.1016/j.medcli.2013.10.013. Epub 2013 Dec 19.
Impact factor:
Publication type: Letter whit IF
Authors: Alijotas-Reig, Jaume; Farran-Codina, Inmaculada; Ferrer-Oliveras, Raquel; Llurba, Elisa et al.
DOI: 10.1016/j.medcli.2013.10.013

[Current therapeutic indications of thalidomide and lenalidomide.]

PMID: 23830554
Journal: MEDICINA CLINICA
Year: 2014
Reference: Med Clin (Barc). 2014 Apr 22;142(8):360-4. doi: 10.1016/j.medcli.2013.04.038. Epub 2013 Jul 3.
Impact factor:
Publication type: Paper in national publication
Authors: Cosiglio, Francisco Javier; Ordi-Ros, Josep et al.
DOI: 10.1016/j.medcli.2013.04.038

Treatment of refractory obstetric antiphospholipid syndrome: the state of the art and new trends in the therapeutic management.

PMID: 23151685
Journal: LUPUS
Year: 2013
Reference: Lupus. 2013 Jan;22(1):6-17. doi: 10.1177/0961203312465782. Epub 2012 Nov 14.
Impact factor:
Publication type: Review in international publication
Authors: Alijotas-Reig, J et al.
DOI: 10.1177/0961203312465782

Usefulness and Limitations of Sequential Serum Tryptase for the Diagnosis of Anaphylaxis in 102 Patients.

PMID: 23018683
Journal: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Year: 2013
Reference: Int Arch Allergy Immunol. 2013;160(2):192-9. doi: 10.1159/000339749. Epub 2012 Sep 25.
Impact factor:
Publication type: Paper in international publication
Authors: Cardona, Victoria; Esteso, Olga; Garriga, Teresa; Guilarte, Mar; Labrador-Horrillo, Moises; Luengo, Olga; Sala-Cunill, Anna; Vicario, Maria et al.
DOI: 10.1159/000339749

Clinical characteristics and one-year survival in heart failure patients more than 85 years of age compared with younger.

PMID: 23385010
Journal: European Journal of Internal Medicine
Year: 2013
Reference: Eur J Intern Med. 2013 Jun;24(4):339-45. doi: 10.1016/j.ejim.2013.01.005. Epub 2013 Feb 4.
Impact factor: 2.049
Publication type: Paper in international publication
Authors: Montero-Perez-Barquero, Manuel, Conde-Martel, Alicia, Formiga, Francesc, Perez-Bocanegra, Carmen, Armengou-Arxe, Arola, Muela-Molinero, Alberto, Sanchez-Sanchez, Cristina, Diez-Manglano, Jesus et al.
DOI: 10.1016/j.ejim.2013.01.005

The epidemiology of anaphylaxis in Europe: a systematic review.

PMID: 24117770
Journal: ALLERGY
Year: 2013
Reference: Allergy. 2013 Nov;68(11):1353-61. doi: 10.1111/all.12272. Epub 2013 Oct 14.
Impact factor: 5.883
Publication type: Review in international publication
Authors: Lack, G, Panesar, S S, Javad, S, de Silva, D, Nwaru, B I, Hickstein, L, Muraro, A, Roberts, G, Worm, M, Bilo, M B et al.
DOI: 10.1111/all.12272

The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis.

PMID: 22012429
Journal: GENES AND IMMUNITY
Year: 2012
Reference: Genes Immun. 2012 Feb;13(2):191-6. doi: 10.1038/gene.2011.72. Epub 2011 Oct 20.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Ma Angeles; Andreu, Jose Luis; Beltran, Emma; Broen, J C A; Callejas-Rubio, Jose Luis; Camps, Mayte; Carmona, F D; Carreira, P; Castellvi, I; Castillo, Ma Jesus et al.
DOI: 10.1038/gene.2011.72

[A 28-years old pregnant woman with systemic lupus erythematosus, proteinuria and arterial hypertension.]

PMID: 22647670
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Nov 3;139(11):489-97. doi: 10.1016/j.medcli.2012.03.016. Epub 2012 May 28.
Impact factor:
Publication type: Editorial in national publication
Authors: ; ; et al.
DOI: 10.1016/j.medcli.2012.03.016

Acute experimental stress evokes a differential gender-determined increase in human intestinal macromolecular permeability.

PMID: 22625665
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2012
Reference: Neurogastroenterol Motil. 2012 Aug;24(8):740-6, e348-9. doi: 10.1111/j.1365-2982.2012.01928.x. Epub 2012 May 24.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2982.2012.01928.x

The European Registry on Obstetric Antiphospholipid Syndrome (EUROAPS): A preliminary first year report.

PMID: 22635227
Journal: LUPUS
Year: 2012
Reference: Lupus. 2012 Jun;21(7):766-8. doi: 10.1177/0961203312440058.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; et al.
DOI: 10.1177/0961203312440058

Efficacy of Cyclophospamide in the Treatment of Interstitial Lung Disease Associated with Systemic Sclerosis.

PMID: 21458128
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2011
Reference: Arch Bronconeumol. 2011 May;47(5):239-45. Epub 2011 Mar 31.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.arbres.2011.01.010

Systemic lupus erythematosus as a first presentation of common variable immunodeficiency associated with infrequent mannose-binding lectin gene polymorphisms.

PMID: 19851769
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2011
Reference: Rheumatol Int. 2011 Apr;31(4):537-41. Epub 2009 Oct 23.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1007/s00296-009-1209-8

SPECT imaging for brain improvement quantification in a patient with cerebrotendinous xanthomatosis.

PMID: 21157207
Journal: CLINICAL NUCLEAR MEDICINE
Year: 2011
Reference: Clin Nucl Med. 2011 Jan;36(1):38-9.
Impact factor:
Publication type: Editorail in international publication
Authors: Bardes, Ignasi; Cuberas-Borros, Gemma; Jacas, Carlos; Jubany, Lluis; Lorenzo-Bosquet, Carles; Selva-O'Callaghan, Albert; Vilardell-Tarres, Miquel et al.
DOI: 10.1097/RLU.0b013e3181feed83

AStream: An R package for annotating LC/MS metabolomic data.

PMID: 21414990
Journal: BIOINFORMATICS
Year: 2011
Reference: Bioinformatics. 2011 May 1;27(9):1339-40. Epub 2011 Mar 16.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1093/bioinformatics/btr138

Aortic involvement in giant cell arteritis.

PMID: 20149900
Journal: AUTOIMMUNITY REVIEWS
Year: 2010
Reference: Autoimmun Rev. 2010 May;9(7):521-4. Epub 2010 Feb 8.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; et al.
DOI: 10.1016/j.autrev.2010.02.014

[Immediate care consultation. An experience of three years.]

PMID: 20144804
Journal: REVISTA CLINICA ESPANOLA
Year: 2010
Reference: Rev Clin Esp. 2010 Jan;210(1):55-56. Epub 2010 Jan 9.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; et al.
DOI: 10.1016/j.rce.2009.02.001

Is obstetric antiphospholipid syndrome a primary nonthrombotic, proinflammatory, complement-mediated disorder related to antiphospholipid antibodies?

PMID: 20040128
Journal: OBSTETRICAL & GYNECOLOGICAL SURVEY
Year: 2010
Reference: Obstet Gynecol Surv. 2010 Jan;65(1):39-45.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas Reig, Jaume; Alijotas-Reig, Jaume; Vilardell-Tarres, Miquel et al.
DOI: 10.1097/OGX.0b013e3181c97809

Inherited antithrombin deficiency and pregnancy: Maternal and fetal outcomes.

PMID: 20047788
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology
Year: 2010
Reference: Eur J Obstet Gynecol Reprod Biol. 2010 Mar;149(1):47-51. Epub 2010 Jan 4.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; Alijotas Reig, Jaume et al.
DOI: 10.1016/j.ejogrb.2009.12.004

[Nutritional support in the home-based hospitalization setting].

PMID: 19266120
Journal: Nutricion Hospitalaria
Year: 2009
Reference: Nutr Hosp. 2009 Jan-Feb;24(1):93-6.
Impact factor: 1.096
Publication type: Paper in national publication
Authors: Chicharro, L, Planas, M, Perez-Portabella, C, Velez, C, San Jose, A et al.
DOI:

Palmar fascitis and polyarthritis as a paraneoplastic syndrome associated with ovarian carcinoma: a case report.

PMID: 22190980
Journal: BMJ case reports
Year: 2009
Reference: BMJ Case Rep. 2009;2009. pii: bcr05.2009.1899. doi: 10.1136/bcr.05.2009.1899. Epub 2009 Dec 22.
Impact factor: 0
Publication type: Paper in international publication
Authors: Bolibar, Esther Pages, Raya, Judith Sanchez, Simeon, Carmen-Pilar, Montesinos, Lluisa, Jou, Nuria, Cuxart, Ampar et al.
DOI: 10.1136/bcr.05.2009.1899

Learning and reliability of colour Doppler ultrasound in giant cell arteritis.

PMID: 19646347
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2009
Reference: Clin Exp Rheumatol. 2009 Jan-Feb;27(1 Suppl 52):S53-8.
Impact factor: 2.364
Publication type: Paper in international publication
Authors: De Miguel, E, Lluch, P, Luna, C, Martin, J A, Martinez, E, Mateo, L, Medeiros, D, Mediavilla, M J, Mera, A, Minguez, S et al.
DOI:

Patients' perceptions of health-related quality of life in rheumatoid arthritis.

PMID: 19562403
Journal: CLINICAL RHEUMATOLOGY
Year: 2009
Reference: Clin Rheumatol. 2009 Oct;28(10):1157-65.
Impact factor: 1.559
Publication type: Paper in international publication
Authors: Oriach, M R, Trabado, C, Ordonez, S, Llopart, E, Clavaguera, T, Nunez, Montserrat, Nunez, Esther, Sanchez, Alex, del Val, Jose Luis, Bonet, Maria et al.
DOI: 10.1007/s10067-009-1215-y

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The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.