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Search Fulltext search Activities Professionals Research groups News - Any - A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants with Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping with an Initial Multiple Ascending Dose Part A to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ENTR-601-45, Followed by Part B to Evaluate the Safety and Efficacy of ENTR-601-45 Open Protocol code: ENTR-601-45-201 EudraCT code: _ Research group: Therapeutics and Innovations in Neuropediatrics and other paediatric rare diseases Service: General Pediatrics and Specialties Principal investigator: Gómez Andrés, David Pathology: Malalties del sistema nerviós Phase: Fase I Estudio de fase 1b que combina dinutuximab beta (DB) con regímenes de quimioterapia de inducción en pacientes con neuroblastoma de alto riesgo de reciente diagnóstico. Open Protocol code: SIOPEN-PILOT01 EudraCT code: No aplica Research group: Childhood Cancer and Blood Disorders Service: Pediatric Oncohematology Principal investigator: Moreno Martín-Retortillo, Lucas Pathology: Tumors Phase: Fase I A phase 1 open-label trial to evaluate the safety, tolerability, pharmacodynamics, pharmacokinetics, and immunogenicity of subcutaneous VIS171 in participants with autoimmune disease(s). Open Protocol code: VIS171-103 EudraCT code: _ Research group: Nephrology and kidney transplantation Service: Nephrology Principal investigator: Sans Atxer, Laia Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més Phase: Fase I Estudio aleatorizado, doble ciego para evaluar la eficacia y laseguridad de CAL101 en pacientes con fibrosis pulmonar idiopática. Open Protocol code: CAL-101-201 EudraCT code: No aplica Research group: Pneumology Service: Pneumology Principal investigator: Villar Gomez, Ana Pathology: Malalties del sistema respiratori Phase: Fase II Estudio de fase 3, multicéntrico y abierto para evaluar la farmacocinética, la farmacodinamia, la eficacia y la seguridad de Ravulizumab en participantes pediátricos (de 2 a <18 años de edad) con Nefropatía primaria por Inmunoglobulina A (NIgA) Open Protocol code: ALXN1210-IgAN-325 EudraCT code: No aplica Research group: Kidney Physiopathology Service: Pediatric Nephrology Principal investigator: Ariceta Iraola, Gema Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més Phase: Fase III A MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL TO ASSESS EFFICACY AND SAFETY OF OMECAMTIV MECARBIL IN PATIENTS WITH SYMPTOMATIC HEART FAILURE WITH SEVERELY REDUCED EJECTION FRACTION Open Protocol code: CY 1033 EudraCT code: No aplica Research group: Cardiovascular Diseases Service: Cardiology Principal investigator: Méndez Fernández, Ana Belén Pathology: Malalties del sistema circulatori Phase: Fase III Estudio de fase 2, aleatorizado, abierto y controlado para evaluar la eficacia y la seguridad de rapcabtagene autoleucel frente a un comparador en participantes con miopatías inflamatorias idiopáticas refractarias graves Open Protocol code: CYTB323L12201 EudraCT code: No aplica Research group: Systemic Diseases Service: Internal Medicine Principal investigator: Selva O'Callaghan, Albert Pathology: Malalties del sistema osteomuscular i del teixit connectiu Phase: Fase II Open-label, single-arm, non-controlled trial to evaluate the safety and tolerability of treprostinil sodium in children below the age of 18 years with pulmonary arterial hypertension (PAH)] Open Protocol code: TREPaed EudraCT code: No aplica Research group: Growth and Development Service: General Pediatrics and Specialties Principal investigator: Moreno Galdó, Antonio Pathology: Malalties del sistema respiratori Phase: Fase III An interventional efficacy and safety phase 3, double-blind, 2-arm study to investigate IV followed by oral fosmanogenix compared with IV caspofungin follow by oral fluconazole in adult participants with candidemia and/or invasive cansidiasis Open Protocol code: FMGX-CS-301 EudraCT code: No aplica Research group: Shock, Organ Dysfunction and Resuscitation Service: RTA ICU Principal investigator: Ferrer Roca, Ricard Pathology: Tumors Phase: Fase III Eficacia de la colchicina en prevención secundaria de eventos vasculares y progresión renal en pacientes con enfermedad renal crónica moderada Open Protocol code: FIBHGM-ECNC002-colchiren EudraCT code: _ Research group: Nephrology and kidney transplantation Service: Nephrology Principal investigator: Bermejo Garcia, Sheila Pathology: Malalties del sistema genitourinari Phase: Fase III Status: Recruiting volunteers Estudio aleatorizado de fase II, doble ciego y controlado con placebo para evaluar la eficacia, la seguridad y la tolerabilidad de RO7204239 en combinación con tirzepatida en participantes con obesidad o sobrepeso y con al menos una comorbilidad relacionada con el peso Open Protocol code: BC45538 EudraCT code: No aplica Research group: Diabetes and Metabolism Service: Endocrinology Principal investigator: Ciudin Mihai, Andreea Pathology: Malalties endocrines, nutricionals i metabòliques Phase: Fase II A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 3 Trial Evaluating the Efficacy and Safety of Felzartamab in Kidney Transplant Recipients with Late Antibody-Mediated Rejection (AMR) (TRANSCEND) Open Protocol code: 299AR301 EudraCT code: No aplica Research group: Nephrology and kidney transplantation Service: Nephrology Principal investigator: Bestard Matamoros, Oriol Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més Phase: Fase III Optimizing Reperfusion to Improve Outcomes and Neurologic Function (ORION): A Multicenter, Double-Blind, Placebo-Controlled, Randomized, Parallel-Group, Phase 2/3 Study to Evaluate the Efficacy and Safety of JX10 in Acute Ischemic Stroke with Late Presentations Open Protocol code: JX10002 EudraCT code: No aplica Research group: Stroke Research Service: Neurology Principal investigator: Molina Cateriano, Carlos Pathology: Malalties del sistema circulatori Phase: Fase III Título del estudio: Estudio de extensión abierto para evaluar la seguridad y la tolerabilidad de sotatercept (MK-7962) utilizando un método por franja de peso en participantes con hipertensión arterial pulmonar (HAP) que reciben el tratamiento de referencia Open Protocol code: MK-7962-031 EudraCT code: No aplica Research group: Pneumology Service: Pneumology Principal investigator: Saez Gimenez, Berta Pathology: Malalties del sistema respiratori Phase: Fase II Status: Recruiting volunteers Estudio de fase III multicéntrico, aleatorizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la seguridad y la eficacia de sovateltida en pacientes con accidente cerebrovascular isquémico agudo Open Protocol code: Sovateltide-ACIS-IND2022 EudraCT code: No aplica Research group: Stroke Research Service: Neurology Principal investigator: Molina Cateriano, Carlos Pathology: Malalties del sistema circulatori Phase: Fase III LIGHTBEAM-U01 Subestudio 01C: Subestudio de fase 1/2 para evaluar la seguridad y la eficacia de patritumab deruxtecán en participantes pediátricos con tumores sólidos en recaída o refractarios. Open Protocol code: MK-9999-01C EudraCT code: No aplica Research group: Childhood Cancer and Blood Disorders Service: Pediatric Oncohematology Principal investigator: Hladun Alvaro, Raquel Pathology: Tumors Phase: Fase I Estudio de fase 1/2, abierto y multicéntrico para evaluar laseguridad, eficacia y cinética celular de YTB323 en participantes con EsclerosisMúltiple Recurrente con actividad de la enfermedad durante el tratamiento previo conuna terapia de alta eficacia Open Protocol code: CYTB323N12101 EudraCT code: No aplica Research group: Clinical Neuroimmunology Service: Neuroimmunology Principal investigator: Montalban Gairín, Xavier Pathology: Malalties del sistema nerviós Phase: Fase I Protocolo de fase III, multicéntrico, aleatorizado, doble ciego, controlado con placebo para evaluar la eficacia y la seguridad de nipocalimab en adultos con enfermedad de Sjögren (SjD) de moderada a grave Open Protocol code: 80202135SJS3001 EudraCT code: No aplica Research group: Systemic Diseases Service: Internal Medicine Principal investigator: Solans Laque, Roser Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més Phase: Fase III Estudio de fase III, multicéntrico, aleatorizado, doble ciego,comparativo con placebo y con grupos paralelos para evaluar la eficacia y la seguridadde tirzepatida una vez a la semana en comparación con placebo en participantes adultoscon diabetes de tipo 1 y obesidad o sobrepeso (SURPASS-T1D-1) I8F-MC-GPJA Open Protocol code: I8F-MC-GPJA EudraCT code: No aplica Research group: Diabetes and Metabolism Service: Endocrinology Principal investigator: Simó Servat, Olga Pathology: Malalties endocrines, nutricionals i metabòliques Phase: Fase III A phase 3 randomized, double-blinded, placebo controlled multicenter trial with open label extesion to evaluate the efficacy, safety and tolerability of efgartigimod PH20 Open Protocol code: ARGX-113-2306 EudraCT code: No aplica Research group: Rheumatology Service: Rheumatology Principal investigator: Marsal Barril, Sara Pathology: Tumors Phase: Fase III Pagination First page « Previous page ‹ … Page 2490 Page 2491 Current page 2492 Page 2493 Page 2494 … Next page › Last page »
