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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Team

Oriol Bestard Matamoros

Oriol Bestard Matamoros

Head of group
Nephrology and kidney transplantation
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Maria Jose Soler Romeo

Maria Jose Soler Romeo

Head of group
Nephrology and kidney transplantation
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Ander Vergara Arana

Ander Vergara Arana

Main researcher
Nephrology and kidney transplantation
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Francesc Moreso Mateos

Francesc Moreso Mateos

Main researcher
Nephrology and kidney transplantation
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Joana Sellarés Roig

Joana Sellarés Roig

Main researcher
Nephrology and kidney transplantation
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M Antonieta Azancot Rivero

M Antonieta Azancot Rivero

Main researcher
Nephrology and kidney transplantation
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Oriol Bestard Matamoros

Oriol Bestard Matamoros

Head of group
Nephrology and kidney transplantation
Read more
Maria Jose Soler Romeo

Maria Jose Soler Romeo

Head of group
Nephrology and kidney transplantation
Read more
Ander Vergara Arana

Ander Vergara Arana

Main researcher
Nephrology and kidney transplantation
Read more
Francesc Moreso Mateos

Francesc Moreso Mateos

Main researcher
Nephrology and kidney transplantation
Read more
Joana Sellarés Roig

Joana Sellarés Roig

Main researcher
Nephrology and kidney transplantation
Read more
M Antonieta Azancot Rivero

M Antonieta Azancot Rivero

Main researcher
Nephrology and kidney transplantation
Read more

Research lines

Desenvolupament de noves mol.lècules inmunomoduladores que prevenen l'activació de l'al·loresposta o autoreactivitat així com altres estratègies que promouen respostes protectores anti-virals

IP: Oriol Bestard Matamoros, Elena Isabel Crespo Gimeno

Estudi de les bases biològiques de patologies glomerulars o sistèmiques amb directe afectació renal com la nefropatia diabètica, així com l'estudi dels diferents mediadors del Fracàs Renal Agut en el context de noxes diferent

IP: Maria Jose Soler Romeo, Concepció Jacobs Cachá

Estudi dels factors biològics que modulen el risc de desenvolupar infeccions oportunistes i neoplàsies després del trasplantament

IP: Oriol Bestard Matamoros, Francesc Moreso Mateos

Estudi dels mecanismes immunològics, funcionals i moleculars que vehiculitzen el rebuig i/o la tolerància de l'empelt, emprant i desenvolupant noves eines diagnostiques no invasives per a personalitzar el tractament immunosupressor després del trasplantament

IP: Oriol Bestard Matamoros, Maria Antonia Emilia Meneghini

Projects

Dissecció i promoció d'immunitat adaptativa específica davant del poliomavirus (BKV) per prevenir la infecció viral després del trasplantament renal (projecte BK-VAX)

IP: Oriol Bestard Matamoros
Collaborators: Miriam Izquierdo Sans , Jose Miguel Zuñiga Vergara
Funding agency: Fundació Catalana de Trasplantament
Funding: 25000
Reference: FCT/BEQUES/2022/ZUÑIGA
Duration: 01/01/2023 - 31/12/2023

Hacia un manejo clínico personalizado de pacientes oncológicos con fracaso renal agudo asociado a los immune-checkpoint inhibitors (ICIs)

IP: Maria Jose Soler Romeo
Collaborators: Oriol Bestard Matamoros, Sheila Bermejo Garcia, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno
Funding agency: Instituto de Salud Carlos III
Funding: 246840
Reference: AC22/00029
Duration: 01/01/2023 - 31/12/2025

Evaluación de la respuesta celular B autoreactiva ANCA-específica como nuevo biomarcador de actividad en la vasculitis asociadas a ANCA

IP: Oriol Bestard Matamoros
Collaborators: -
Funding agency: Sociedad Española de Nefrología (S.E.N.)
Funding: 24000
Reference: SENEFRO/AYUDAS.INVES/2022/BESTARD
Duration: 10/10/2022 - 10/10/2024

Nefrologia i Trasplantament Renal

IP: Oriol Bestard Matamoros
Collaborators: Marina Lopez Martinez, Francesc Moreso Mateos, Natalia Ramos Terrades, Maria Jose Soler Romeo, Joana Sellarés Roig, Pamela Dominguez Baez, Ander Vergara Arana, Irene Agraz Pamplona, Sheila Bermejo Garcia, Mariona Juvé Torres, Irina Betsabe Torres Rodriguez, Alba Torija Recasens, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno, Laura Donadeu Casassas, Carmen Llorens Cebriá, Nuria Bolaños Peruga, Maria Tormo Fabios, Manel Perelló Carrascosa, Maria Antonia Emilia Meneghini
Funding agency: AGAUR no fer servir-correcte 4301-37
Funding: 40000
Reference: 2021 SGR 00883
Duration: 01/01/2022 - 31/12/2024

Publications

Disarming the Old Foe. Restoring T-Cell Immune Function with mTor-Inhibitors to Tackle Cytomegalovirus Infection.

PMID: 34969818
Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Year: 2022
Reference: J Am Soc Nephrol. 2022 Jan;33(1):6-8. doi: 10.1681/ASN.2021111471.
Impact factor: 10.121
Publication type: Editorail in international publication
Authors: Bestard, Oriol; Crespo, Elena et al.
DOI: 10.1681/ASN.2021111471

Reconciling short-term clinical and Immunological outcomes of SARS-CoV-2 vaccination in Solid Organ Transplant recipients.

PMID: 34554648
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2022
Reference: Am J Transplant. 2022 Feb;22(2):673-675. doi: 10.1111/ajt.16855. Epub 2021 Oct 5.
Impact factor: 8.086
Publication type: Letter or abstract
Authors: Toapanta, Nestor; Esperalba, Juliana; Campos-Varela, Isabel; Pont, Teresa; Len, Oscar; Campins, Magda; Moreso, Francesc; Crespo, Elena; Munoz, Marina; Lopez, Manuel et al.
DOI: 10.1111/ajt.16855

A comprehensive assessment of long-term SARS-CoV-2-specific adaptive immune memory in convalescent COVID-19 Solid Organ Transplant recipients.

PMID: 35124011
Journal: KIDNEY INTERNATIONAL
Year: 2022
Reference: Kidney Int. 2022 May;101(5):1027-1038. doi: 10.1016/j.kint.2021.12.029. Epub 2022 Feb 4.
Impact factor: 10.612
Publication type: Paper in international publication
Authors: Fava, Alexandre; Donadeu, Laura; Jouve, Thomas; Gonzalez-Costello, Jose; Llado, Laura; Santana, Carolina; Toapanta, Nestor; Lopez, Manuel; Pernin, Vincent; Facundo, Carme et al.
DOI: 10.1016/j.kint.2021.12.029

Parathyroid hormone and phosphate homeostasis in patients with Bartter and Gitelman syndrome: an international cross-sectional study.

PMID: 35137195
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Feb 7. pii: 6523371. doi: 10.1093/ndt/gfac029.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Decramer, Stephane; Devuyst, Olivier; van Dyck, Maria; Ferraro, Pietro Manuel; Fila, Marc; Francisco, Telma; Ghiggeri, Gian Marco; Gondra, Leire; Guarino, Stefano; Hooman, Nakysa et al.
DOI: 10.1093/ndt/gfac029

Clinical triage of patients on kidney replacement therapy presenting with COVID-19: an ERACODA registry analysis.

PMID: 34129039
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2021
Reference: Nephrol Dial Transplant. 2021 Dec 2;36(12):2308-2320. doi: 10.1093/ndt/gfab196.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Veldhuizen, Nicoline M H, Mitra, Sandip, Jayanti, Anuradha, Vart, Priya, Coca, Armando, Gallieni, Maurizio, Ovrehus, Marius Altern, Midtvedt, Karsten, Abd ElHafeez, Samar, Gandolfini, Iliaria et al.
DOI: 10.1093/ndt/gfab196

A Prospective Multicenter Trial to Evaluate Urinary Metabolomics for Non-invasive Detection of Renal Allograft Rejection (PARASOL): Study Protocol and Patient Recruitment.

PMID: 35071266
Journal: Frontiers in Medicine
Year: 2021
Reference: Front Med (Lausanne). 2022 Jan 7;8:780585. doi: 10.3389/fmed.2021.780585. eCollection 2021.
Impact factor: 5.093
Publication type: Paper in international publication
Authors: Banas, Miriam C, Bohmig, Georg A, Viklicky, Ondrej, Rostaing, Lionel P, Jouve, Thomas, Guirado, Lluis, Facundo, Carme, Bestard, Oriol, Grone, Hermann-Josef, Kobayashi, Kazuhiro et al.
DOI: 10.3389/fmed.2021.780585

Endothelial ADAM17 Expression in the Progression of Kidney Injury in an Obese Mouse Model of Pre-Diabetes.

PMID: 35008648
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Dec 25;23(1). pii: ijms23010221. doi: 10.3390/ijms23010221.
Impact factor: 5.924
Publication type: Paper in international publication
Authors: Palau, Vanesa, Jarrin, Josue, Villanueva, Sofia, Benito, David, Marquez, Eva, Rodriguez, Eva, Soler, Maria Jose, Oliveras, Anna, Gimeno, Javier, Sans, Laia et al.
DOI: 10.3390/ijms23010221

Funding kidney research as a public health priority: challenges and opportunities.

PMID: 32888017
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2021
Reference: Nephrol Dial Transplant. 2021 Dec 31;37(1):21-28. doi: 10.1093/ndt/gfaa163.
Impact factor: 5.992
Publication type: Review in international publication
Authors: Zoccali, Carmine, Vanholder, Raymond, Wagner, Carsten A, Anders, Hans-Joachim, Blankestijn, Peter J, Bruchfeld, Annette, Capasso, Giovambattista, Cozzolino, Mario, Dekker, Friedo W, Fliser, Danilo et al.
DOI: 10.1093/ndt/gfaa163

A Rejection Gene Expression Score in Indication and Surveillance Biopsies Is Associated with Graft Outcome.

PMID: 33153205
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2020
Reference: Int J Mol Sci. 2020 Nov 3;21(21). pii: ijms21218237. doi: 10.3390/ijms21218237.
Impact factor: 4.556
Publication type: Paper in international publication
Authors: Seron, Daniel, Moreso, Francesc, O'Valle, Francisco, Perello, Manel, Chamoun, Betty, Caraben, Anna, Torres, Irina B, Sellares, Joana, Jimenez, Raquel, Toapanta, Nestor et al.
DOI: 10.3390/ijms21218237

Impact of the COVID-19 pandemic on Spanish Nephrology Services.

PMID: 33131910
Journal: NEFROLOGIA
Year: 2020
Reference: Nefrologia. 2020 Nov - Dec;40(6):579-584. doi: 10.1016/j.nefro.2020.08.002. Epub 2020 Oct 6.
Impact factor: 1.544
Publication type: Editorial in national publication
Authors: Salgueira Lazo, Mercedes, Del Pino Y Pino, Maria Dolores, Ortiz, Alberto, Macia Heras, Manuel, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2020.08.002

SGLT2 inhibitors for non-diabetic kidney disease: drugs to treat CKD that also improve glycaemia.

PMID: 33123352
Journal: Clinical Kidney Journal
Year: 2020
Reference: Clin Kidney J. 2020 Oct 9;13(5):728-733. doi: 10.1093/ckj/sfaa198. eCollection 2020 Oct.
Impact factor: 3.388
Publication type: Editorail in international publication
Authors: Ortiz, Alberto, Gorriz, Jose Luis, Soler, Maria Jose, Fernandez-Fernandez, Beatriz, Sarafidis, Pantelis, Kanbay, Mehmet, Navarro-Gonzalez, Juan F et al.
DOI: 10.1093/ckj/sfaa198

Nephrology: achieving sustainability.

PMID: 32901289
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2020
Reference: Nephrol Dial Transplant. 2020 Dec 4;35(12):2030-2033. doi: 10.1093/ndt/gfaa193.
Impact factor: 4.531
Publication type: Editorail in international publication
Authors: Blankestijn, Peter J, Bruchfeld, Annette, Cozzolino, Mario, Fliser, Danilo, Fouque, Denis, Gansevoort, Ron, Goumenos, Dimitrios, Massy, Ziad A, Rychlik, Ivan, Soler, Maria Jose et al.
DOI: 10.1093/ndt/gfaa193

Single-cell RNA profiling of glomerular cells in diabetic kidney: a step forward for understanding diabetic nephropathy.

PMID: 32016058
Journal: Annals of Translational Medicine
Year: 2019
Reference: Ann Transl Med. 2019 Dec;7(Suppl 8):S340. doi: 10.21037/atm.2019.09.104.
Impact factor: 3.689
Publication type: Editorail in international publication
Authors: Soler, Maria Jose, Batlle, Daniel et al.
DOI: 10.21037/atm.2019.09.104

Diabetic retinopathy as an independent predictor of subclinical cardiovascular disease: baseline results of the PRECISED study.

PMID: 31908800
Journal: BMJ Open Diabetes Research & Care
Year: 2019
Reference: BMJ Open Diabetes Res Care. 2019 Dec 29;7(1):e000845. doi: 10.1136/bmjdrc-2019-000845. eCollection 2019.
Impact factor: 5.067
Publication type: Paper in international publication
Authors: Simo, Rafael, Baneras, Jordi, Hernandez, Cristina, Rodriguez-Palomares, Jose, Valente, Filipa, Gutierrez, Laura, Gonzalez-Alujas, Teresa, Ferreira, Ignacio, Aguade-Bruix, Santiago, Seron, Daniel et al.
DOI: 10.1136/bmjdrc-2019-000845

Complement Activation and Thrombotic Microangiopathies.

PMID: 31694864
Journal: Clinical Journal of the American Society of Nephrology
Year: 2019
Reference: Clin J Am Soc Nephrol. 2019 Dec 6;14(12):1719-1732. doi: 10.2215/CJN.05830519. Epub 2019 Nov 6.
Impact factor: 6.243
Publication type: Paper in international publication
Authors: Palomo, Marta, Blasco, Miquel, Molina, Patricia, Lozano, Miquel, Praga, Manuel, Torramade-Moix, Sergi, Martinez-Sanchez, Julia, Cid, Joan, Escolar, Gines, Carreras, Enric et al.
DOI: 10.2215/CJN.05830519

Prediabetes is a risk factor for cardiovascular disease following renal transplantation.

PMID: 31611066
Journal: KIDNEY INTERNATIONAL
Year: 2019
Reference: Kidney Int. 2019 Dec;96(6):1374-1380. doi: 10.1016/j.kint.2019.06.026. Epub 2019 Aug 14.
Impact factor: 8.306
Publication type: Paper in international publication
Authors: Porrini, Esteban, Diaz, Juan Manuel, Moreso, Francesc, Lauzurrica, Ricardo, Ibernon, Meritxel, Torres, Irene Silva, Ruiz, Rocio Benitez, Rodriguez Rodriguez, Ana Elena, Mallen, Patricia Delgado, Bayes-Genis, Beatriz et al.
DOI: 10.1016/j.kint.2019.06.026

Reduced TCR-signalling contributes to impaired Th17 responses in tolerant kidney transplant recipients.

PMID: 28902773
Journal: TRANSPLANTATION
Year: 2018
Reference: Transplantation. 2018 Jan;102(1):e10-e17. doi: 10.1097/TP.0000000000001920.
Impact factor: 3.678
Publication type: Paper in international publication
Authors: Tsui, Tjir-Li, Norris, Sonia, John, Susan, Boardman, Dominic A, Lechler, Robert I, Lombardi, Giovanna, Hernandez-Fuentes, Maria P, Kamra, Yogesh, Mobillo, Paula, Runglall, Manohursingh et al.
DOI: 10.1097/TP.0000000000001920

Systematic review of the methods predictive of the functionality of kidney transplantation.

PMID: 28803679
Journal: Actas Urologicas Espanolas
Year: 2018
Reference: Actas Urol Esp. 2018 May;42(4):218-226. doi: 10.1016/j.acuro.2017.07.004. Epub 2017 Aug 10.
Impact factor: 1.181
Publication type: Paper in national publication
Authors: Miret Alomar, E, Trilla Herrera, E, Lorente Garcia, D, Regis Placido, L, Lopez Del Campo, R, Pont Castellana, T, Moreso Mateos, F, Seron Micas, D, Morote Robles, J, Cuadras Sole, M et al.
DOI: 10.1016/j.acuro.2017.07.004

Relationships between iron dose, hospitalizations and mortality in incident haemodialysis patients: a propensity-score matched approach.

PMID: 28992120
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2018
Reference: Nephrol Dial Transplant. 2018 Jan 1;33(1):160-170. doi: 10.1093/ndt/gfx209.
Impact factor: 4.6
Publication type: Paper in international publication
Authors: Varas, Javier, Ramos, Rosa, Aljama, Pedro, Perez-Garcia, Rafael, Moreso, Francesc, Pinedo, Miguel, Ignacio Merello, Jose, Stuard, Stefano, Canaud, Bernard, Martin-Malo, Alejandro et al.
DOI: 10.1093/ndt/gfx209

Randomized Controlled Trial Assessing the Impact of Tacrolimus Versus Cyclosporine on the Incidence of Posttransplant Diabetes Mellitus.

PMID: 30450457
Journal: Kidney international reports
Year: 2018
Reference: Kidney Int Rep. 2018 Jul 11;3(6):1304-1315. doi: 10.1016/j.ekir.2018.07.009. eCollection 2018 Nov.
Impact factor: 0
Publication type: Paper in international publication
Authors: Ruiz, Juan C, Marrero Miranda, Domingo, Perez-Tamajon, Lourdes, Rodriguez, Aurelio, Gonzalez-Rinne, Ana, Alvarez, Alejandra, Perez-Carreno, Estefania, de la Vega Prieto, Maria Jose, Henriquez, Fernando, Gallego, Roberto et al.
DOI: 10.1016/j.ekir.2018.07.009

Health literacy and chronic kidney disease.

PMID: 27837925
Journal: NEFROLOGIA
Year: 2017
Reference: Nefrologia. 2017 Mar - Apr;37(2):115-117. doi: 10.1016/j.nefro.2016.10.001. Epub 2016 Nov 9.
Impact factor: 1.207
Publication type: Paper in national publication
Authors: Costa-Requena, Gema, Seron, Daniel, Cantarell, M Carmen, Moreso, Francesc et al.
DOI: 10.1016/j.nefro.2016.10.001

Inflammation in Early Kidney Allograft Surveillance Biopsies With and Without Associated Tubulointerstitial Chronic Damage as a Predictor of Fibrosis Progression and Development of De Novo Donor Specific Antibodies.

PMID: 27163535
Journal: TRANSPLANTATION
Year: 2017
Reference: Transplantation. 2017 Jun;101(6):1410-1415. doi: 10.1097/TP.0000000000001216.
Impact factor: 3.69
Publication type: Paper in international publication
Authors: Garcia-Carro, Clara, Dorje, Christina, Asberg, Anders, Midtvedt, Karsten, Scott, Helge, Reinholt, Finn P, Holdaas, Hallvard, Seron, Daniel, Reisaeter, Anna V et al.
DOI: 10.1097/TP.0000000000001216

Health-related behaviours after 1 year of renal transplantation.

PMID: 26359287
Journal: JOURNAL OF HEALTH PSYCHOLOGY
Year: 2017
Reference: J Health Psychol. 2017 Mar;22(4):505-514. doi: 10.1177/1359105315604889. Epub 2016 Jul 10.
Impact factor:
Publication type: Letter or abstract
Authors: Costa-Requena, Gema, Cantarell, M Carmen, Moreso, Francesc J, Parramon, Gemma, Seron, Daniel et al.
DOI: 10.1177/1359105315604889

Lorraine Racusen and Kim Solez Awarded the Gold Medal of the Catalan Transplant Society.

PMID: 29198652
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2017
Reference: Transplant Proc. 2017 Dec;49(10):2240-2242. doi: 10.1016/j.transproceed.2017.09.044.
Impact factor: 0.908
Publication type: Letter or abstract
Authors: Seron, D, Roman, A et al.
DOI: 10.1016/j.transproceed.2017.09.044

Multiple parapelvic cysts in Fabry disease.

PMID: 27061865
Journal: NEFROLOGIA
Year: 2016
Reference: Nefrologia. 2016 May-Jun;36(3):310-2. doi: 10.1016/j.nefro.2015.12.003. Epub 2016 Apr 6.
Impact factor: 1.207
Publication type: Paper in national publication
Authors: Azancot, Maria A, Vila, Josefa, Dominguez, Carmen, Serres, Xavier, Espinel, Eugenia et al.
DOI: 10.1016/j.nefro.2015.12.003

Effectiveness of Cinacalcet in Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism Not Receiving Dialysis.

PMID: 27588942
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Sep 2;11(9):e0161527. doi: 10.1371/journal.pone.0161527. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Sune-Negre, Josep-Maria, Perez-Ricart, Ariadna, Galicia-Basart, Maria, Alcalde-Rodrigo, Maria, Segarra-Medrano, Alfons, Montoro-Ronsano, Jose-Bruno et al.
DOI: 10.1371/journal.pone.0161527

Clinical evolution of post-transplant diabetes mellitus.

PMID: 26538615
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2016
Reference: Nephrol Dial Transplant. 2016 Mar;31(3):495-505. doi: 10.1093/ndt/gfv368. Epub 2015 Nov 3.
Impact factor: 4.085
Publication type: Paper in international publication
Authors: Ruiz, Juan C, Porrini, Esteban L, Diaz, Jose M, Moreso, Francisco, Delgado Mallen, Patricia I, Silva Torres, Irene, Ibernon, Meritxell, Bayes-Genis, Beatriz, Benitez-Ruiz, Rocio, Lampreabe, Ildefonso et al.
DOI: 10.1093/ndt/gfv368

Controlled randomized study comparing the cardiovascular profile of everolimus with tacrolimus in renal transplantation.

PMID: 27648523
Journal: TRANSPLANT INTERNATIONAL
Year: 2016
Reference: Transpl Int. 2016 Dec;29(12):1317-1328. doi: 10.1111/tri.12862. Epub 2016 Oct 17.
Impact factor: 2.835
Publication type: Clinical Trials
Authors: Sanchez-Fructuoso, Ana, Seron, Daniel, Diaz, Joan M, Rengel, Manuel, Oppenheimer, Federico, Hernandez, Domingo, Paravisini, Alexandra, Saval, Nuria, Morales, Jose M, Pascual, Julio et al.
DOI: 10.1111/tri.12862

Clinical features, course and prognosis of idiopathic membranous nephropathy depending on the presence of antibodies against M-type phospholipase A2 receptor.

PMID: 26306972
Journal: NEFROLOGIA
Year: 2015
Reference: Nefrologia. 2015;35(5):479-86. doi: 10.1016/j.nefro.2015.05.026. Epub 2015 Jul 7.
Impact factor: 1.223
Publication type: Paper in national publication
Authors: Jatem Escalante, Elias, Segarra Medrano, Alfons, Carnicer Caceres, Clara, Martin-Gomez, M Adoracion, Salcedo Allende, Maria Teresa, Ostos Roldan, Helena, Agraz Pamplona, Irene et al.
DOI: 10.1016/j.nefro.2015.05.026

Medium-Term Renal Function in a Large Cohort of Stable Kidney Transplant Recipients Converted From Twice-Daily to Once-Daily Tacrolimus.

PMID: 27500226
Journal: Transplantation direct
Year: 2015
Reference: Transplant Direct. 2015 Aug 5;1(7):e24. doi: 10.1097/TXD.0000000000000536. eCollection 2015 Aug.
Impact factor: 0
Publication type: Paper in international publication
Authors: Osuna, Antonio, Guirado, Lluis, Burgos, Dolores, Cantarell, Carme, Fernandez, Ana, Franco, Antonio, Gentil, Miguel Angel, Mazuecos, Auxiliadora, Torregrosa, Josep Vicenc, Huertas, Ernesto Gomez et al.
DOI: 10.1097/TXD.0000000000000536

Drug-related acute renal failure in hospitalised patients.

PMID: 26474529
Journal: NEFROLOGIA
Year: 2015
Reference: Nefrologia. 2015 Nov-Dec;35(6):523-32. doi: 10.1016/j.nefro.2015.09.007. Epub 2015 Oct 21.
Impact factor: 1.223
Publication type: Paper in national publication
Authors: Iavecchia, Lujan, Cereza Garcia, Gloria, Sabate Gallego, Monica, Vidal Guitart, Xavier, Ramos Terrades, Natalia, de la Torre, Judith, Segarra Medrano, Alfons, Agusti Escasany, Antonia et al.
DOI: 10.1016/j.nefro.2015.09.007

Disappearance of T Cell-Mediated Rejection Despite Continued Antibody-Mediated Rejection in Late Kidney Transplant Recipients.

PMID: 25377077
Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Year: 2015
Reference: J Am Soc Nephrol. 2015 Jul;26(7):1711-20. doi: 10.1681/ASN.2014060588. Epub 2014 Nov 6.
Impact factor: 9.466
Publication type: Letter or abstract
Authors: Reeve, Jeff, Einecke, Gunilla, Sellares, Joana, Chang, Jessica, Famulski, Konrad, Hidalgo, Luis G, Salazar, Israel D R, Merino Lopez, Maribel, Matas, Arthur, Picton, Michael et al.
DOI: 10.1681/ASN.2014060588

Prevalence, diagnostic value and clinical characteristics associated with the presence of circulating levels and renal deposits of antibodies against the M-type phospholipase A2 receptor in idiopathic membranous nephropathy.

PMID: 24798555
Journal: NEFROLOGIA
Year: 2014
Reference: Nefrologia. 2014 May 21;34(3):353-9. doi: 10.3265/Nefrologia.pre2013.Dec.12291. Epub 2014 Feb 10.
Impact factor: 1.442
Publication type: Paper in national publication
Authors: Segarra-Medrano, Alfonso, Jatem-Escalante, Elias, Quiles-Perez, M Teresa, Salcedo, M Teresa, Arbos-Via, M Antonia, Ostos, Helena, Valtierra, Naiara, Carnicer-Caceres, Clara, Agraz-Pamplona, Irene et al.
DOI: 10.3265/Nefrologia.pre2013.Dec.12291

Evolution of antibody titre against the M-type phospholipase A2 receptor and clinical response in idiopathic membranous nephropathy patients treated with tacrolimus.

PMID: 25036063
Journal: NEFROLOGIA
Year: 2014
Reference: Nefrologia. 2014;34(4):491-7. doi: 10.3265/Nefrologia.pre2014.Jun.12536.
Impact factor: 1.442
Publication type: Paper in national publication
Authors: Segarra-Medrano, Alfons, Jatem-Escalante, Elias, Carnicer-Caceres, Clara, Salcedo, M Teresa, Agraz-Pamplona, Irene, Valtierra, Naiara, Ostos-Roldan, Elena, Arredondo, Karla V, Jaramillo, Juliana et al.
DOI: 10.3265/Nefrologia.pre2014.Jun.12536

[Persistent microhaematuria with negative or low proteinuria].

PMID: 24463867
Journal: NEFROLOGIA
Year: 2014
Reference: Nefrologia. 2014;34(1):110-4. doi: 10.3265/Nefrologia.pre2013.Jul.12096.
Impact factor: 1.442
Publication type: Paper in national publication
Authors: Gutierrez, Eduardo, Moreno, Juan A, Praga, Manuel, Gutierrez, E, Zamora, I, Ballarin, J A, Arce, Y, Jimenez, S, Quereda, C, Olea, T et al.
DOI: 10.3265/Nefrologia.pre2013.Jul.12096

CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance.

PMID: 24263531
Journal: PEDIATR NEPHROL
Year: 2014
Reference: Pediatr Nephrol. 2014 Aug;29(8):1363-71. doi: 10.1007/s00467-013-2679-1. Epub 2013 Nov 22.
Impact factor: 2.881
Publication type: Paper in international publication
Authors: Cara-Fuentes, Gabriel, Wei, Changli, Ishimoto, Takuji, Rivard, Christopher, Johnson, Richard J, Reiser, Jochen, Garin, Eduardo H, Segarra, Alfons et al.
DOI: 10.1007/s00467-013-2679-1

Extracorporeal depuration technique as treatment of acute kidney injury related to multiple myeloma.

PMID: 23735155
Journal: THERAPEUTIC APHERESIS AND DIALYSIS
Year: 2013
Reference: Ther Apher Dial. 2013 Jun;17(3):351-2. doi: 10.1111/1744-9987.12009. Epub 2013 Feb 17.
Impact factor: 1.529
Publication type: Letter or abstract
Authors: Gil Carballeira, Ivan, Fort Ros, Joan, Ramos Sanchez, Rosa et al.
DOI: 10.1111/1744-9987.12009

Should high-flux hemodialysis be replaced by online hemodiafiltration for treating end-stage renal disease patients?

PMID: 24236671
Journal: Journal of Comparative Effectiveness Research
Year: 2013
Reference: J Comp Eff Res. 2013 Jul;2(4):347-9. doi: 10.2217/cer.13.30.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Maduell, Francisco, Moreso, Francesc et al.
DOI: 10.2217/cer.13.30

Potential impact of microarray diagnosis of T cell-mediated rejection in kidney transplants: The INTERCOM study.

PMID: 23915426
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2013
Reference: Am J Transplant. 2013 Sep;13(9):2352-63. doi: 10.1111/ajt.12387. Epub 2013 Aug 5.
Impact factor: 6.192
Publication type: Paper in international publication
Authors: Chang, J, Matas, A, Picton, M, De Freitas, D, Bromberg, J, Seron, D, Sellares, J, Einecke, G, Reeve, J, Pereira, A B et al.
DOI: 10.1111/ajt.12387

Treatment of idiopathic focal segmental glomerulosclerosis: options in the event of resistance to corticosteroids and calcineurin inhibitors.

PMID: 23897176
Journal: NEFROLOGIA
Year: 2013
Reference: Nefrologia. 2013;33(4):448-61. doi: 10.3265/Nefrologia.pre2013.Jan.11871.
Impact factor: 1.274
Publication type: Review in national publication
Authors: Ostos-Roldan, Elena, Quiles-Perez, M Teresa, Arbos-Via, M Antonia, Ramos-Terrades, Natalia, Carnicer-Caceres, Clara, Jatem-Escalante, Elias, Segarra-Medrano, Alfonso, Agraz-Pamplona, Irene et al.
DOI: 10.3265/Nefrologia.pre2013.Jan.11871

Early treatment with eculizumab in atypical haemolytic uraemic syndrome.

PMID: 26069743
Journal: Clinical kidney journal
Year: 2012
Reference: Clin Kidney J. 2012 Feb;5(1):31-3. doi: 10.1093/ndtplus/sfr157. Epub 2012 Jan 31.
Impact factor: 0
Publication type: Letter or abstract
Authors: Garjau, Maria, Azancot, Maria, Ramos, Rosa, Sanchez-Corral, Pilar, Montero, Maria Angeles, Seron, Daniel et al.
DOI: 10.1093/ndtplus/sfr157

The natural history of clinical operational tolerance after kidney transplantation through twenty-seven cases.

PMID: 22974211
Journal: AMERICAN JOURNAL OF TRANSPLANTATION
Year: 2012
Reference: Am J Transplant. 2012 Dec;12(12):3296-307. doi: 10.1111/j.1600-6143.2012.04249.x. Epub 2012 Sep 13.
Impact factor: 6.394
Publication type: Paper in international publication
Authors: Brouard, S, Pallier, A, Soulillou, J-P, Giral, M, Testa, A, Ranbant, M, Hoitsma, A, Cantarell, C, Renaudin, K, Foucher, Y et al.
DOI: 10.1111/j.1600-6143.2012.04249.x

Late evolution of kidney transplants in elderly donors and recipients receiving initial immunosuppressant treatment with daclizumab, mycophenolate mofetil, and delayed introduction of tacrolimus.

PMID: 22806279
Journal: NEFROLOGIA
Year: 2012
Reference: Nefrologia. 2012 Jul 17;32(4):446-54. doi: 10.3265/Nefrologia.pre2012.Mar.11024.
Impact factor: 1
Publication type: Paper in international publication
Authors: Gonzalez-Roncero, Francisco M, Gentil-Govantes, Miguel A, Gonzalez-Molina, Miguel, Rivero, Manuel, Cantarell, Carmen, Alarcon, Antonio, Franco, Antonio, Sanchez-Plumed, Jaime, Lampreabe, Ildefonso, Lauzurica, Ricardo et al.
DOI: 10.3265/Nefrologia.pre2012.Mar.11024

Development and validation of a specific questionnaire for evaluating the impact of gastrointestinal symptoms on the health-related quality of life of transplant patients.

PMID: 22664001
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2012
Reference: Transplant Proc. 2012 Jun;44(5):1281-6. doi: 10.1016/j.transproceed.2012.01.114.
Impact factor: 1.005
Publication type: Paper in international publication
Authors: Miras, M, Ortega, F, Bravo, J, Cantarell, C, Cofan, F, Gomez-Bravo, M A, Guinea, G, Ussetti, P, Crespo-Leiro, M G et al.
DOI: 10.1016/j.transproceed.2012.01.114

Subclinical rejection in renal transplants is associated with low serum mannose-binding lectin levels.

PMID: 25018901
Journal: Kidney international supplements
Year: 2011
Reference: Kidney Int Suppl (2011). 2011 Aug;1(2):36-39. doi: 10.1038/kisup.2011.10.
Impact factor: 0
Publication type: Paper in international publication
Authors: Ibernon, Meritxell, Moreso, Francesc, Seron, Daniel et al.
DOI: 10.1038/kisup.2011.10

Efficacy and safety of combined cyclosporin A and mycophenolate mofetil therapy in patients with cyclosporin-resistant focal segmental glomerulosclerosis.

PMID: 21468162
Journal: NEFROLOGIA
Year: 2011
Reference: Nefrologia. 2011;31(3):286-91. doi: 10.3265/Nefrologia.pre2011.Feb.10870. Epub 2011 Mar 15.
Impact factor: 0.738
Publication type: Paper in national publication
Authors: Camps Domenech, J, Majo Masferrer, J, Pou Clave, L, Vila Presas, J, Segarra Medrano, A et al.
DOI: 10.3265/Nefrologia.pre2011.Feb.10870

Histological findings in two renal transplants accomplishing operational tolerance criteria.

PMID: 25984157
Journal: NDT plus
Year: 2011
Reference: NDT Plus. 2011 Jun;4(3):198-200. doi: 10.1093/ndtplus/sfr001. Epub 2011 Mar 7.
Impact factor: 0.42
Publication type: Paper in international publication
Authors: Azancot, M A, Moreso, F, Cantarell, C, Torres, I B, Seron, D R et al.
DOI: 10.1093/ndtplus/sfr001

Assessing glomerular filtration rate in hospitalized patients: a comparison between CKD-EPI and four cystatin C-based equations.

PMID: 21852668
Journal: Clinical Journal of the American Society of Nephrology
Year: 2011
Reference: Clin J Am Soc Nephrol. 2011 Oct;6(10):2411-20. doi: 10.2215/CJN.01150211. Epub 2011 Aug 18.
Impact factor: 4.763
Publication type: Paper in international publication
Authors: Segarra, Alfonso, de la Torre, Judith, Ramos, Natalia, Quiroz, Augusto, Garjau, Maria, Torres, Irina, Azancot, M Antonia, Lopez, Montserrat, Sobrado, Ana et al.
DOI: 10.2215/CJN.01150211

Dramatic event after acute ischaemic steal syndrome following arm arteriovenous fistulae.

PMID: 25984063
Journal: NDT plus
Year: 2010
Reference: NDT Plus. 2010 Oct;3(5):490-1. doi: 10.1093/ndtplus/sfq100. Epub 2010 Jun 10.
Impact factor: 0
Publication type: Letter or abstract
Authors: Quiroz, Augusto, Torres, Irina, Romero, Alejandro, Ramos, Rosa, Gil, Ivan et al.
DOI: 10.1093/ndtplus/sfq100

Improvement in late renal allograft survival between 1990 and 2002 in Spain: results from a multicentre case-control study.

PMID: 20230537
Journal: TRANSPLANT INTERNATIONAL
Year: 2010
Reference: Transpl Int. 2010 Sep;23(9):907-13. Epub 2010 Mar 11.
Impact factor: 3.254
Publication type: Paper in international publication
Authors: Bustamante, J, Moreso, Francesc, Alonso, Angel, Gentil, Miguel A, Gonzalez-Molina, Miguel, Capdevila, Lluis, Marcen, Roberto, Pascual, Julio, Seron, Daniel, Franco, A et al.
DOI: 10.1111/j.1432-2277.2010.01075.x

Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection.

PMID: 20150436
Journal: AMERICAN JOURNAL OF PATHOLOGY
Year: 2010
Reference: Am J Pathol. 2010 Apr;176(4):1696-704. Epub 2010 Feb 11.
Impact factor: 5.673
Publication type: Paper in international publication
Authors: Hueso, Miguel, Navarro, Estanis, Moreso, Francesc, O'Valle, Francisco, Perez-Riba, Merce, Del Moral, Raimundo Garcia, Grinyo, Josep M, Seron, Daniel et al.
DOI: 10.2353/ajpath.2010.090411

Continuous positive airway pressure treatment in sleep apnea patients with resistant hypertension: a randomized, controlled trial.

PMID: 20577130
Journal: JOURNAL OF HYPERTENSION
Year: 2010
Reference: J Hypertens. 2010 Oct;28(10):2161-8.
Impact factor: 4.988
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1097/HJH.0b013e32833b9c63

[Progression factors in chronic kidney disease. Immunological mechanisms].

PMID: 19675656
Journal: NEFROLOGIA
Year: 2009
Reference: Nefrologia. 2009;29 Suppl 1:7-15. doi: 10.3265/NEFROLOGIA.2009.29.S.1.5632.EN.FULL.
Impact factor: 0.674
Publication type: Paper in national publication
Authors: Capdevila Plaza, Luis, Cubero, Juan Jose, Luna, Enrique, Hernandez Gallego, Roman et al.
DOI: 10.3265/NEFROLOGIA.2009.29.S.1.5632.EN.FULL

[Scintigraphy of the intraperitoneal cavity using technetium 99m as a diagnostic technique for diaphragmatic leaks in peritoneal dialysis: regarding two cases].

PMID: 19554061
Journal: NEFROLOGIA
Year: 2009
Reference: Nefrologia. 2009;29(3):263-5. doi: 10.3265/Nefrologia.2009.29.3.5285.en.full.
Impact factor: 0.674
Publication type: Letter or abstract
Authors: Ramos Sanchez, R, Antonia Azancot, M, Bartolome Espinosa, J, Vilaplana Molto, M, Camps Domenech, J, Gil Carballeira, I et al.
DOI: 10.3265/Nefrologia.2009.29.3.5285.en.full

[Is mycophenolate mofetil more effective than conservative treatment for primary membranous glomerulonephritis?].

PMID: 20221227
Journal: NEFROLOGIA
Year: 2009
Reference: Nefrologia. 2009;29(6 Suppl):49-52. doi: 10.3265/NEFROLOGIA.2009.29.S.E.noID.36.free.
Impact factor: 0.674
Publication type: Letter or abstract
Authors: Segarra Medrano, Alfons et al.
DOI: 10.3265/NEFROLOGIA.2009.29.S.E.noID.36.free

Chronic allograft nephropathy--a clinical syndrome: early detection and the potential role of proliferation signal inhibitors.

PMID: 19719730
Journal: CLINICAL TRANSPLANTATION
Year: 2009
Reference: Clin Transplant. 2009 Nov-Dec;23(6):769-77. Epub 2009 Aug 27.
Impact factor: 1.915
Publication type: Review in national publication
Authors: Neumayer, Hans H, Oyen, Ole, Pascual, Julio, Pohanka, Erich, Ruiz, Juan C, Scolari, Maria P, Stefoni, Sergio, Seron, Daniel, Sparacino, Vito, Arns, Wolfgang et al.
DOI: 10.1111/j.1399-0012.2009.01057.x

Thesis

Afectación renal en el paciente oncológico: de la fisiopatología a la repercusión

PhD student: Monica Bolufer Cardona
Director/s: Maria Jose Soler Romeo, Clara García Carro
University:
Year: 2022

Mecanismos de acción del bloqueo SGLT2 en la protección cardiorrenal en la diabetes tipo 2.

PhD student: Ander Vergara Arana
Director/s: Maria Jose Soler Romeo, Concepció Jacobs Cachá
University: Universidad Autònoma de Barcelona
Year: 2021

Contribución de la inflamación del aloinjerto renal a la inflamación sistémica

PhD student: Anna Caraben Redaño
Director/s: Daniel Serón Micas
University: Universidad Autònoma de Barcelona
Year: 2020

Valor predictivo del fenotipo molecular sobre la progresion de las lesiones renales en biopsias de seguimiento en trasplante renal

PhD student: Irina Betsabe Torres Rodriguez
Director/s: Francesc Moreso Mateos
University: Universidad Autònoma de Barcelona
Year: 2017

Alteraciones de la inmunidad innata, inflamación de bajo grado y progresión de la aterosclerosis subclínica en pacientes con insuficiencia renal y en trasplantados renales

PhD student: M Antonieta Azancot Rivero, M Antonieta Azancot Rivero
Director/s: Daniel Serón Micas
University: Universidad Autònoma de Barcelona
Year: 2017

Estudio exploratorio observacional y prospectivo de la maduración de la fístula arteriovenosa (FAV) nativa. Estudio "MAFAVI

PhD student: Iván Gil Carballeira
Director/s: Daniel Serón Micas
University: Universidad Autònoma de Barcelona
Year: 2017

Marcadores bioquímicos de lesión endotelial, sistema fibrinolítico y microalbuminuria en HTA esencial.

PhD student: Natalia Ramos Terrades
Director/s: Alfons Segarra Medrano, Vicenç Fonollosa Pla
University: Universidad Autònoma de Barcelona
Year: 2010

Blog

News

The Kidney Transplantation Unit of Vall d'Hebron Hospital was the first European center to include patients in the post-authorization efficacy study, the step prior to approval by the European Medicines Agency.

Vall d'Hebron has announced a research collaboration with Pure Transplant Solutions, LLC (PTS) led by Dr. Oriol Bestard, head of the Nephrology and Kidney Transplant group at VHIR.

Dels 117 pacients trasplantats d’òrgan sòlid infectats per SARS-CoV-2 en els vuit mesos que comprèn l’estudi (de novembre a juny de 2021), un 88% van infectar-se en el període prevacunació (103 pacients, que van contreure COVID-19 de novembre a març).

Job offers

Laboratory Technician - Nephrology Research Group
Start date:
28/06/2023
End date:
12/07/2023
Document: Download
RESEARCH SUPPORT PhD - Nephrology and Transplantation Group
Start date:
17/05/2023
End date:
06/06/2023
Document: Download
Study Nurse Study Coordinator - Nephrology and Transplantation Group
Start date:
12/05/2023
End date:
01/06/2023
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