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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Team

Alfredo Guillen Del Castillo

Alfredo Guillen Del Castillo

Main researcher
Systemic Diseases
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Anna Sala Cunill

Anna Sala Cunill

Postdoctoral researcher
Systemic Diseases
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Antonio San Jose Laporte

Antonio San Jose Laporte

Systemic Diseases
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José Ordi Ros

José Ordi Ros

Main researcher
Systemic Diseases
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José Pardos Gea

José Pardos Gea

Systemic Diseases
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Mar Guilarte Clavero

Mar Guilarte Clavero

Main researcher
Systemic Diseases
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Alfredo Guillen Del Castillo

Alfredo Guillen Del Castillo

Main researcher
Systemic Diseases
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Anna Sala Cunill

Anna Sala Cunill

Postdoctoral researcher
Systemic Diseases
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Antonio San Jose Laporte

Antonio San Jose Laporte

Systemic Diseases
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José Ordi Ros

José Ordi Ros

Main researcher
Systemic Diseases
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José Pardos Gea

José Pardos Gea

Systemic Diseases
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Mar Guilarte Clavero

Mar Guilarte Clavero

Main researcher
Systemic Diseases
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Research lines

Antibodies to types I and IV collagen in patients with antiphospholipid syndrome and systemic lupus erythematosus. Correlation with valvulopathy

Antibodies to collagen have been identified in patients with infectious (endocarditis) and inflammatory (rheumatic) valvulopathies. The objective is to assess a possible role of autoantibodies against types I and IV collagen in the valvulopathy of patients with antiphospholipid syndrome and systemic lupus erythematosus.

IP: José Pardos Gea

Cancer and myositis. Relevance of the anti-p155 antibodies and importance of the screening for cancer by Positron Emission Tomography and Computed Tomography (PET/CT).

Anti-p155 antibodies seem to be useful for the diagnosis of paraneoplastic myopathies. We have studied their prevalence and their diagnosis value in a cohort of 137 patients with inflammatory myopathies and we have observed that they have a high negative predictive value. On the other hand, the screening by PET/TC does not contribute much to the conventional screening of cancer in these patients.

IP: Albert Selva O'Callaghan

Canine-myositis study

In this study we collaborate with the Faculty of Veterinary located at the Barcelona Autonomous University (Dr. Santiago Lavin) along with the Department of Pathology of the University of California (Prof G. Diane Shelton).

The only myositis spontaneous animal model is found in dogs, especially in Collies, and when it accompanies cancer, in Boxers. Several antibodies have been described in dogs but it is not known if they are also found in humans. Alternatively, myositis specific antibodies may be positive or negative in dogs. If human beings and dogs share a common autoimmune response, a new door can be opened to deepen in the etiopathogenia and the species-specificity of these illnesses.


IP: Albert Selva O'Callaghan

Capillaroscopy abnormalities in primary Sjögren’s syndrome.

We want to describe the capillaroscopy alterations observed in patients with Raynaud's phenomenon and primary Sjögren’s syndrome. Our main objective is to establish if there is a specific capillaroscopic pattern associated with Sjögren syndrome and if it is related to visceral extraglandular involvement.

IP: Roser Solans Laque, Vicenç Fonollosa Pla

Projects

OPVIH (Optimización del proceso VIH): Definición del mapa del recorrido de la persona VIH y oportunidades para su optimización mediante salud digital.

IP: Adria Curran Fàbregas
Collaborators: Anna Sala Cunill, Vicenç Falcó Ferrer, Yolima Cossio Gil, Ignasi Cardona Pascual, Paula Suanzes Diez, Jordi Navarro Mercadé, Joaquin Burgos Cibrian, Núria Castany Viñas, Maria Belén Gutiérrez Iglesias, Silvina Andrea Magnani
Funding agency: Laboratorio ViiV Healthcare
Funding: 55000
Reference: VIIV/BECAS/2023/CURRAN
Duration: 15/01/2024 - 14/01/2026

Caracterización de las células patogénicas del músculo y piel de pacientes con Dermatomiositis y Síndrome Antisintetasa y estudio de aplicabilidad traslacional

IP: Ernesto Trallero Araguas
Collaborators: Miriam Izquierdo Sans
Funding agency: Fundación Española de Reumatología
Funding: 30000
Reference: FER/TRALLERO/2023
Duration: 21/10/2023 - 20/10/2024

Ajuts Grups de Recerca (SGR) 2022

IP: Jaume Alijotas Reig
Collaborators: Moisés Labrador Horrillo, Carmen Pilar Simeón i Aznar, Anna Sala Cunill, Roser Solans Laque, Segundo Bujan Rivas, Mar Guilarte Clavero, Vicenç Fonollosa Pla, Fernando Martínez Valle, Victòria Cardona Dahl, Francesc Miro Mur, Alfredo Guillen Del Castillo, Albert Selva O'Callaghan, José Pardos Gea, Laura Donaire Lancharro, Ariadna Anunciacion Llunell
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00048
Duration: 01/01/2022 - 30/06/2025

Malalties infeccioses

IP: Vicenç Falcó Ferrer
Collaborators: Jose Santos Santiago, Maria Luisa Aznar Ruiz de Alegria, Adria Curran Fàbregas, Jorge Nestor Garcia Perez, Oscar Len Abad, Mª Carmen Ferrer Barberà, Javier Gomis Rodriguez, Diana Pou Ciruelo, Begoña Treviño Maruri, Nuria Fernández Hidalgo, Joan Gavaldà Santapau, Juan Espinosa Pereiro, Bibiana Planas Ribas, Ma Dolores Rodríguez Pardo, Pau Bosch Nicolau, David Perea Pérez, Israel Molina Romero, Patricia Álvarez López, Luis Lopez Perez, Vicente Descalzo Jorro, Marta Sanchiz Cruz, Nuria Serre Delcor, Laura Escola Verge, Julia Sellares Nadal, Fernando M Salvador Velez, Isabel Ruiz Camps, Jordi Gómez i Prat, María José Buzón Gómez, Hakima Ouaarab Essadek, Paula Suanzes Diez, Jordi Navarro Mercadé, Esperanza Esteban Serna, Raisa Morales Martinez, Joaquin Burgos Cibrian, Nerea Sanchez Gaona, Joan Rey Cano, Adrián Sánchez Montalvá, Cristina Mancebo Perez, Montserrat Llinás Vidal, Ana Gallego Cortes, Maider Arando Lasagabaster, Ibai Los Arcos Bertiz, Claudia Broto Cortes, Ester Marquez Algaba, Benito Almirante Gragera, Desideria Martinez Rascón, Meritxell Genesca Ferrer, Ines Mercedes Oliveira Souto, Silvina Andrea Magnani, Yasmine Margaret Baktash
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00764
Duration: 01/01/2022 - 30/06/2025

Publications

CORRESPONDENCE/COMMENTS ON ACR/EULAR ANTIPHOSPHOLIPID SYNDROME CLASSIFICATION CRITERIA.

PMID: 38200647
Journal: Arthritis & Rheumatology
Year: 2024
Reference: Arthritis Rheumatol. 2024 Jan 10. doi: 10.1002/art.42792.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Belizna, Cristina; Canti, Valentina; de Carolis, Sara; Esteve-Valverde, Enrique; Ferrer-Oliveras, Raquel; Hoxha, Ariella; Jaume Alijotas-Reig, J; Latino, Omar; Lefkou, Eleftheria; Llurba, Elisa et al.
DOI: 10.1002/art.42792

WAO consensus on DEfinition of Food Allergy SEverity (DEFASE).

PMID: 36910595
Journal: World Allergy Organization Journal
Year: 2023
Reference: World Allergy Organ J. 2023 Mar 2;16(3):100753. doi: 10.1016/j.waojou.2023.100753. eCollection 2023 Mar.
Impact factor:
Publication type: Paper in international publication
Authors: Alvaro-Lozano, Montserrat; Ansotegui, Ignacio J; Arasi, Stefania; Asaria, Miqdad; Begin, Philippe; Boyle, Robert; Bozzola, Martin; Brough, Helen; Cardona, Victoria; Chinthrajah, R Sharon et al.
DOI: 10.1016/j.waojou.2023.100753

Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection.

PMID: 37019909
Journal: Nature Communications
Year: 2023
Reference: Nat Commun. 2023 Apr 5;14(1):1887. doi: 10.1038/s41467-023-37559-w.
Impact factor:
Publication type: Paper in international publication
Authors: Buzon, Maria J; Esperalba, Juliana; Falco, Vicenc; Genesca, Meritxell; Kuguel, Sebastian G; Kuguel, Sebastian G; Mancebo, Cristina; Mancebo, Cristina; Pieren, Daan K J; Rey-Cano, Joan et al.
DOI: 10.1038/s41467-023-37559-w

Efficacy and Safety of Anakinra Plus Standard of Care for Patients With Severe COVID-19: A Randomized Phase 2/3 Clinical Trial.

PMID: 37027155
Journal: JAMA Network Open
Year: 2023
Reference: JAMA Netw Open. 2023 Apr 3;6(4):e237243. doi: 10.1001/jamanetworkopen.2023.7243.
Impact factor:
Publication type: Paper in international publication
Authors: Abdilla-Bonias, Noelia; Alende-Sixto, Rosario; Alvarez-Suarez, Ana Maria; Alvarez-Troncoso, Jorge; Andrade-Pina, Ariadna Helena; Arevalo, Coral; Argibay, Ana Belen; Arnaez, Ruben; Arnalich, Francisco; Bara, Nuria et al.
DOI: 10.1001/jamanetworkopen.2023.7243

Low complement levels are related to poor obstetric outcomes in women with obstetric antiphospholipid syndrome. The EUROAPS Registry Study Group.

PMID: 37028222
Journal: PLACENTA
Year: 2023
Reference: Placenta. 2023 May;136:29-34. doi: 10.1016/j.placenta.2023.04.001. Epub 2023 Apr 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume; Anunciacion-Llunell, Ariadna; Arnau, Anna; Belizna, Cristina; Canti, Valentina; Cervera, Ricard; Chighizola, Cecilia B; De Carolis, Sara; Espinosa, Gerard; Esteve-Valverde, Enrique et al.
DOI: 10.1016/j.placenta.2023.04.001

A pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solutions in open fractures (Aqueous-PREP): statistical analysis plan.

PMID: 36096826
Journal: Trials
Year: 2022
Reference: Trials. 2022 Sep 12;23(1):772. doi: 10.1186/s13063-022-06541-0.
Impact factor:
Publication type: Paper in international publication
Authors: Abbott, Harper; Acerboni-Flores, Francesc; Achor, Timothy S; Adams, John D; Ahn, James S; Al-Asiri, Jamal; Alavedra-Massana, Anna; Alnasser, Ahmad; Altman, Kyle M; Amirhekmat, Arya et al.
DOI: 10.1186/s13063-022-06541-0

Aqueous skin antisepsis before surgical fixation of open fractures (Aqueous-PREP): a multiple-period, cluster-randomised, crossover trial.

PMID: 36244384
Journal: LANCET
Year: 2022
Reference: Lancet. 2022 Oct 15;400(10360):1334-1344. doi: 10.1016/S0140-6736(22)01652-X.
Impact factor:
Publication type: Paper in international publication
Authors: Abbott, Harper; Acerboni-Flores, Francesc; Achor, Timothy S; Adams, John D; Al-Asiri, Jamal; Alavedra-Massana, Anna; Alnasser, Ahmad; Altman, Kyle M; Amirhekmat, Arya; Anderson, Matthew et al.
DOI: 10.1016/S0140-6736(22)01652-X

Association of Patient-Level and Hospital-Level Factors With Timely Fracture Care by Race.

PMID: 36449289
Journal: JAMA Network Open
Year: 2022
Reference: JAMA Netw Open. 2022 Nov 1;5(11):e2244357. doi: 10.1001/jamanetworkopen.2022.44357.
Impact factor:
Publication type: Paper in international publication
Authors: Abbott, Harper; Acerboni-Flores, Francesc; Achor, Timothy S; Adams, John D; Al-Asiri, Jamal; Alavedra-Massana, Anna; Alnasser, Ahmad; Altman, Kyle M; Amirhekmat, Arya; Anderson, Matthew et al.
DOI: 10.1001/jamanetworkopen.2022.44357

Anti-Polymyositis/Scl Antibodies in Systemic Sclerosis: Clinical Associations in a Multicentric Spanish Cohort and Review of the Literature.

PMID: 33938499
Journal: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
Year: 2022
Reference: J Clin Rheumatol. 2022 Jan 1;28(1):e180-e188. doi: 10.1097/RHU.0000000000001676.
Impact factor: 3.517
Publication type: Paper in international publication
Authors: Iniesta Arandia, Nerea; Espinosa, Gerard; Guillen Del Castillo, Alfredo; Tolosa-Vilella, Carles; Colunga-Arguelles, Dolores; Gonzalez de Echavarri Perez de Heredia, Cristina; Lledo, Gema M; Comet, Luis Saez; Ortego-Centeno, Norberto; Vargas Hito, Jose Antonio et al.
DOI: 10.1097/RHU.0000000000001676

Long-term Follow-up in Adult Patients with Cystic Fibrosis and Deep Intronic Splicing Variants.

PMID: 35698963
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Jul;57(7):501-503. doi: 10.1016/j.arbr.2020.11.017.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: Polverino, Eva, Culebras, Mario, Clofent, David, Garcia Arumi, Elena, Tizzano, Eduardo F, de Gracia, Javier, Gartner, Silvia, Fernandez-Alvarez, Paula, Alvarez, Antonio, Loor, Karina et al.
DOI: 10.1016/j.arbr.2020.11.017

Can we Train the Immune System of Patients With Cystic Fibrosis?

PMID: 35699016
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Nov;57(11):708-710. doi: 10.1016/j.arbr.2020.10.016.
Impact factor: 4.872
Publication type: Letter or abstract
Authors: Assante, Giulio, Martinez-Gallo, Monica, Traversi, Letizia, Tur-Torres, Jordi, Romero Mesones, Christian Eduardo, Chang-Macchiu, Patricia, Alvarez, Antoni, Clofent Alarcon, David, Polverino, Eva, Torres-Sierra, Sandra et al.
DOI: 10.1016/j.arbr.2020.10.016

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

PMID: 34597274
Journal: JOURNAL OF CLINICAL INVESTIGATION
Year: 2021
Reference: J Clin Invest. 2021 Dec 1;131(23). pii: 152386. doi: 10.1172/JCI152386.
Impact factor: 14.808
Publication type: Paper in international publication
Authors: O'Byrne, Sheila M, Nakanishi, Tomoko, Pigazzini, Sara, Degenhardt, Frauke, Cordioli, Mattia, Butler-Laporte, Guillaume, Nafria-Jimenez, Beatriz, Hov, Johannes R, Migeotte, Isabelle, Renieri, Alessandra et al.
DOI: 10.1172/JCI152386

Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes.

PMID: 34096881
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2021
Reference: Ann Rheum Dis. 2021 Apr 1. pii: annrheumdis-2021-219884. doi: 10.1136/annrheumdis-2021-219884.
Impact factor: 19.103
Publication type: Paper in international publication
Authors: Distler, J H W, Acosta-Herrera, Marialbert, Kerick, Martin, Lopez-Isac, Elena, Assassi, Shervin, Beretta, Lorenzo, Simeon-Aznar, Carmen Pilar, Ortego-Centeno, Norberto, Proudman, Susanna M, Hunzelmann, Nicolas et al.
DOI: 10.1136/annrheumdis-2021-219884

Utility of recombinant human TSH stimulation test in the follow-up of patients with differentiated thyroid cancer depending on basal thyroglobulin results.

PMID: 37362557
Journal: Advances in laboratory medicine
Year: 2020
Reference: Adv Lab Med. 2020 Jan 7;1(1):20190017. doi: 10.1515/almed-2019-0017. eCollection 2020 Mar.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, Estibaliz; Ferrer, Roser; Galofre, Juan Carlos; Gonzalez, Alvaro; Macias, Monica; Perdomo, Carolina; Sandua, Amaia et al.
DOI: 10.1515/almed-2019-0017

A Cross-National Comparison of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome at Tertiary Care Settings from the US and Spain.

PMID: 34109300
Journal: American journal of social sciences and humanities
Year: 2020
Reference: Am J Soc Sci Humanit. 2020;5(1):104-115. doi: 10.20448/801.51.104.115. Epub 2019 Dec 19.
Impact factor: 0
Publication type: Paper in international publication
Authors: Bhatia, Shaun, Olczyk, Nicole, Jason, Leonard A, Alegre, Jose, Fuentes-Llanos, Judith, Castro-Marrero, Jesus et al.
DOI: 10.20448/801.51.104.115

Experts document on methotrexate use in combined therapy with biological or targeted synthetic disease modifying drugs in patients with rheumatoid arthritis.

PMID: 33041228
Journal: Reumatologia clinica
Year: 2020
Reference: Reumatol Clin (Engl Ed). 2020 Oct 8. pii: S1699-258X(20)30200-X. doi: 10.1016/j.reuma.2020.08.003.
Impact factor: 0
Publication type: Paper in national publication
Authors: Tornero-Molina, Jesus, Castellvi, Ivan, de Agustin-de Oro, Juan Jose, Escudero, Alejandro, Garcia-Vicuna, Rosario, Gonzalez-Gay, Miguel Angel, Hidalgo, Cristina, Rubio, Esteban, Sanmarti, Raimon, Casamira, Nuria et al.
DOI: 10.1016/j.reuma.2020.08.003

Complement genes contribute sex-biased vulnerability in diverse disorders.

PMID: 32499649
Journal: NATURE
Year: 2020
Reference: Nature. 2020 Jun;582(7813):577-581. doi: 10.1038/s41586-020-2277-x. Epub 2020 May 11.
Impact factor: 42.778
Publication type: Paper in international publication
Authors: Seidman, Christine E, Kamitaki, Nolan, Sekar, Aswin, Handsaker, Robert E, de Rivera, Heather, Tooley, Katherine, Morris, David L, Taylor, Kimberly E, Whelan, Christopher W, Tombleson, Philip et al.
DOI: 10.1038/s41586-020-2277-x

Specific Association of HLA-DRB1*03 With Anti-Carbamylated Protein Antibodies in Patients With Rheumatoid Arthritis.

PMID: 30277011
Journal: Arthritis & Rheumatology
Year: 2019
Reference: Arthritis Rheumatol. 2019 Mar;71(3):331-339. doi: 10.1002/art.40738. Epub 2019 Jan 28.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, Lydia; Balsa, Alejandro; Boveda, Maria Dolores; Castano-Nunez, Angel L; Fernandez-Gutierrez, Benjamin; Gomez-Reino, Juan J; Gonzalez, Antonio; Gonzalez-Alvaro, Isidoro; Gonzalez-Escribano, Maria Francisca; Herranz, Eva et al.
DOI: 10.1002/art.40738

ARIA guideline 2019: treatment of allergic rhinitis in the German health system.

PMID: 32176226
Journal: Allergologie select
Year: 2019
Reference: Allergol Select. 2019 Dec 30;3(1):22-50. doi: 10.5414/ALX02120E. eCollection 2019.
Impact factor: 0
Publication type: Paper in international publication
Authors: Vogelberg, Christian, Fuchs, Thomas, Gerstlauer, Michael, Hormann, Karl, Jakob, Thilo, Jung, Kirsten, Kopp, Matthias V, Mahler, Vera, Merk, Hans, Mulleneisen, Norbert et al.
DOI: 10.5414/ALX02120E

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.

PMID: 30597673
Journal: CLINICAL AND EXPERIMENTAL ALLERGY
Year: 2019
Reference: Clin Exp Allergy. 2019 Apr;49(4):442-460. doi: 10.1111/cea.13333. Epub 2019 Mar 12.
Impact factor: 4.741
Publication type: Paper in international publication
Authors: Cecchi, Lorenzo, De Feo, Giulia, Illario, M, Stellato, Cristiana, Fonseca, Joao, Malva, Joao, Morais-Almeida, Mario, Pereira, Ana Maria, Todo-Bom, Ana Maria, Kvedariene, Violeta et al.
DOI: 10.1111/cea.13333

Association of Functional Polymorphisms of KIR3DL1/DS1 With Behcet's Disease.

PMID: 31849952
Journal: Frontiers in Immunology
Year: 2019
Reference: Front Immunol. 2019 Nov 29;10:2755. doi: 10.3389/fimmu.2019.02755. eCollection 2019.
Impact factor: 4.716
Publication type: Paper in international publication
Authors: Castano-Nunez, Angel, Montes-Cano, Marco-Antonio, Garcia-Lozano, Jose-Raul, Ortego-Centeno, Norberto, Garcia-Hernandez, Francisco-Jose, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Julia, Maria-Rosa, Solans, Roser et al.
DOI: 10.3389/fimmu.2019.02755

MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.

PMID: 30386555
Journal: Clinical and Translational Allergy
Year: 2018
Reference: Clin Transl Allergy. 2018 Oct 25;8:45. doi: 10.1186/s13601-018-0227-6. eCollection 2018.
Impact factor: 3.539
Publication type: Review in international publication
Authors: Bousquet, J, Arnavielhe, S, Bedbrook, A, Bewick, M, Laune, D, Mathieu-Dupas, E, Murray, R, Onorato, G L, Pepin, J L, Picard, R et al.
DOI: 10.1186/s13601-018-0227-6

Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Analysis of Data From the Histology-Independent, Phase 2, Open-label VE-BASKET Study.

PMID: 29188284
Journal: JAMA Oncology
Year: 2018
Reference: JAMA Oncol. 2018 Mar 1;4(3):384-388. doi: 10.1001/jamaoncol.2017.5029.
Impact factor: 20.871
Publication type: Paper in international publication
Authors: Arcila, Maria E, Ulaner, Gary, Abdel-Wahab, Omar, Pitcher, Bethany, Makrutzki, Martina, Riehl, Todd, Baselga, Jose, Hyman, David M, Durham, Benjamin, Martinez-Valle, Ferran et al.
DOI: 10.1001/jamaoncol.2017.5029

Hepatobiliary involvement in systemic sclerosis and the cutaneous subsets: Characteristics and survival of patients from the Spanish RESCLE Registry.

PMID: 29246416
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2018
Reference: Semin Arthritis Rheum. 2018 Jun;47(6):849-857. doi: 10.1016/j.semarthrit.2017.10.004. Epub 2017 Oct 6.
Impact factor: 4.498
Publication type: Paper in international publication
Authors: Madronero-Vuelta, Ana Belen, Perales-Fraile, Isabel, Pla-Salas, Xavier, Fernandez-De-La-Puebla, Rafael A, Fonollosa-Pla, Vicent, Tolosa-Vilella, Carles, Chamorro, Antonio-J, Vargas Hitos, Jose Antonio, Freire, Mayka, Ortego-Centeno, Norberto et al.
DOI: 10.1016/j.semarthrit.2017.10.004

First clinical symptom as a prognostic factor in systemic sclerosis: results of a retrospective nationwide cohort study.

PMID: 29214548
Journal: CLINICAL RHEUMATOLOGY
Year: 2018
Reference: Clin Rheumatol. 2018 Apr;37(4):999-1009. doi: 10.1007/s10067-017-3936-7. Epub 2017 Dec 7.
Impact factor: 2.365
Publication type: Paper in international publication
Authors: Verdejo, G, Rubio-Rivas, Manuel, Corbella, Xavier, Pestana-Fernandez, Melany, Tolosa-Vilella, Carles, Guillen-Del Castillo, Alfredo, Colunga-Arguelles, Dolores, Trapiella-Martinez, Luis, Iniesta-Arandia, Nerea, Castillo-Palma, Maria Jesus et al.
DOI: 10.1007/s10067-017-3936-7

Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer.

PMID: 28423537
Journal: Oncotarget
Year: 2017
Reference: Oncotarget. 2017 Mar 28;8(13):21930-21937. doi: 10.18632/oncotarget.15748.
Impact factor:
Publication type: Paper in international publication
Authors: Adamo, Barbara; Albanell, Joan; Alonso, Immaculada; Altomare, Vittorio; Amato, Michela; Aya, Francisco; Caballero, Rosalia; Carrasco, Eva; de la Haba, Juan; Fernandez, Pedro et al.
DOI: 10.18632/oncotarget.15748

Protein Z and atherosclerotic disease: a less close relationship than though.

PMID: 27844302
Journal: JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Year: 2017
Reference: J Thromb Thrombolysis. 2017 Apr;43(3):387-389. doi: 10.1007/s11239-016-1457-x.
Impact factor: 2.142
Publication type: Letter or abstract
Authors: Pardos-Gea, Jose et al.
DOI: 10.1007/s11239-016-1457-x

Recommendations by the Spanish Society of Rheumatology for the management of patients diagnosed with rheumatoid arthritis who cannot be treated with methotrexate.

PMID: 27825791
Journal: Reumatologia clinica
Year: 2017
Reference: Reumatol Clin. 2017 May - Jun;13(3):127-138. doi: 10.1016/j.reuma.2016.10.002. Epub 2016 Nov 5.
Impact factor: 0
Publication type: Paper in international publication
Authors: Garcia-Vicuna, Rosario, Martin-Martinez, Maria Auxiliadora, Gonzalez-Crespo, Maria Rosa, Tornero-Molina, Jesus, Fernandez-Nebro, Antonio, Blanco-Garcia, Francisco Javier, Blanco-Alonso, Ricardo, Marsal-Barril, Sara et al.
DOI: 10.1016/j.reuma.2016.10.002

DNA demethylation of inflammasome-associated genes is enhanced in patients with cryopyrin-associated periodic syndromes.

PMID: 27394913
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2017
Reference: J Allergy Clin Immunol. 2017 Jan;139(1):202-211.e6. doi: 10.1016/j.jaci.2016.05.016. Epub 2016 Jul 7.
Impact factor: 13.081
Publication type: Paper in international publication
Authors: Vento-Tormo, Roser, Alvarez-Errico, Damiana, Garcia-Gomez, Antonio, Hernandez-Rodriguez, Jose, Bujan, Segundo, Basagana, Maria, Mendez, Maria, Yague, Jordi, Juan, Manel, Arostegui, Juan I et al.
DOI: 10.1016/j.jaci.2016.05.016

Migraines Are Correlated with Higher Levels of Nitrate-, Nitrite-, and Nitric Oxide-Reducing Oral Microbes in the American Gut Project Cohort.

PMID: 27822557
Journal:
Year: 2016
Reference: mSystems. 2016 Oct 18;1(5):e00105-16. doi: 10.1128/mSystems.00105-16. eCollection 2016 Sep-Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Gilbert, Jack A; Gonzalez, Antonio; Hyde, Embriette; Knight, Rob; Sangwan, Naseer; Viirre, Erik et al.
DOI: 10.1128/mSystems.00105-16

Long-Term Safety and Efficacy of Epratuzumab in the Treatment of Moderate-to- Severe Systemic Lupus Erythematosus: Results From an Open-Label Extension Study.

PMID: 26316325
Journal: ARTHRITIS CARE & RESEARCH
Year: 2016
Reference: Arthritis Care Res (Hoboken). 2016 Apr;68(4):534-43. doi: 10.1002/acr.22694.
Impact factor: 3.229
Publication type: Paper in international publication
Authors: Gordon, C, Wallace, D J, Hobbs, K, Clowse, M E B, Petri, M, Strand, V, Pike, M, Merrill, J T, Leszczynski, P, Neuwelt, C M et al.
DOI: 10.1002/acr.22694

The Spanish version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for fibromyalgia: reliability and validity assessment.

PMID: 26752202
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2016
Reference: Clin Exp Rheumatol. 2016 Mar-Apr;34(2 Suppl 96):S55-8. Epub 2016 Jan 9.
Impact factor: 2.495
Publication type: Paper in international publication
Authors: Hernandez, Jose L, Casanueva, Benigno, Garcia-Fructuoso, Ferran, Belenguer, Rafael, Alegre, Cayetano, Moreno-Muelas, Jose V, Gonzalez-Gay, Miguel A, Pina, Tinitario et al.
DOI:

VARIAR Study: Assessment of short-term efficacy and safety of rituximab compared to an tumor necrosis factor alpha antagonists as second-line drug therapy in patients with rheumatoid arthritis refractory to a first tumor necrosis factor alpha antagonist.

PMID: 26831256
Journal: Reumatologia clinica
Year: 2016
Reference: Reumatol Clin. 2016 Nov - Dec;12(6):319-322. doi: 10.1016/j.reuma.2015.11.019. Epub 2016 Jan 29.
Impact factor: 0
Publication type: Paper in national publication
Authors: Torrente-Segarra, Vicenc, Acosta Pereira, Asuncion, Morla, Rosa, Ruiz, Jose Miguel, Clavaguera, Teresa, Figuls, Ramon, Corominas, Hector, Geli, Carme, Rosello, Rosa, Alegre, Cayetano et al.
DOI: 10.1016/j.reuma.2015.11.019

Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry.

PMID: 25038238
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2015
Reference: Ann Rheum Dis. 2015 Nov;74(11):2043-9. doi: 10.1136/annrheumdis-2013-204991. Epub 2014 Jul 18.
Impact factor: 10.377
Publication type: Paper in international publication
Authors: Bader-Meunier, B, Levy, R, Gerard, L, Kuemmerle-Deschner, J, Lachmann, H J, Kone-Paut, I, Cantarini, L, Woo, P, Naselli, A, Ozen, S et al.
DOI: 10.1136/annrheumdis-2013-204991

Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes.

PMID: 24326009
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2015
Reference: Ann Rheum Dis. 2015 Mar;74(3):603-10. doi: 10.1136/annrheumdis-2013-204361. Epub 2013 Dec 10.
Impact factor: 10.377
Publication type: Paper in international publication
Authors: Nakagawa, Kenji, Gonzalez-Roca, Eva, Souto, Alejandro, Kawai, Toshinao, Saito, Megumu K, Ohara, Osamu, Kambe, Naotomo, Yasumi, Takahiro, Izawa, Kazushi, Kawai, Tomoki et al.
DOI: 10.1136/annrheumdis-2013-204361

Statins and myositis: the role of anti-HMGCR antibodies.

PMID: 26492593
Journal: Expert Review of Clinical Immunology
Year: 2015
Reference: Expert Rev Clin Immunol. 2015;11(12):1277-9. doi: 10.1586/1744666X.2015.1102632. Epub 2015 Oct 22.
Impact factor: 2.484
Publication type: Editorail in international publication
Authors: Selva-O'Callaghan, Albert, Alvarado-Cardenas, Marcelo, Marin, Ana, Pinal-Fernandez, Iago et al.
DOI: 10.1586/1744666X.2015.1102632

Association between nailfold capillaroscopy findings and pulmonary function tests in patients with systemic sclerosis.

PMID: 25399393
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2015
Reference: J Rheumatol. 2015 Feb;42(2):222-7. doi: 10.3899/jrheum.140276. Epub 2014 Nov 15.
Impact factor: 3.187
Publication type: Paper in international publication
Authors: Castellvi, Ivan, Simeon-Aznar, Carmen Pilar, Sarmiento, Monica, Fortuna, Ana, Mayos, Mercedes, Geli, Carme, Diaz-Torne, Cesar, Moya, Patricia, De Llobet, Josep Maria, Casademont, Jordi et al.
DOI: 10.3899/jrheum.140276

Tocilizumab for retinal vasoproliferative tumor secondary to juvenile idiopathic arthritis-associated uveitis: a case report.

PMID: 24061910
Journal: GRAEF ARCH CLIN EXP
Year: 2014
Reference: Graefes Arch Clin Exp Ophthalmol. 2014 Jan;252(1):163-4. doi: 10.1007/s00417-013-2466-5. Epub 2013 Sep 24.
Impact factor: 2.333
Publication type: Letter or abstract
Authors: Adan, Alfredo, Mesquida, Marina, Llorenc, Victor, Modesto, Consuelo et al.
DOI: 10.1007/s00417-013-2466-5

Biological insights from 108 schizophrenia-associated genetic loci.

PMID: 25056061
Journal: NATURE
Year: 2014
Reference: Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22.
Impact factor: 42.351
Publication type: Paper in international publication
Authors: Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Bruggeman, Richard, Buccola, Nancy G, Buckner, Randy L, Byerley, William, Cahn, Wiepke, Cai, Guiqing, Campion, Dominique et al.
DOI: 10.1038/nature13595

Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus.

PMID: 25199642
Journal: Arthritis & rheumatology (Hoboken, N.J.)
Year: 2014
Reference: Arthritis Rheumatol. 2014 Dec;66(12):3521-3. doi: 10.1002/art.38870.
Impact factor: 0
Publication type: Letter whit IF
Authors: Lopez-Isac, Elena, Bossini-Castillo, Lara, Guerra, Sandra G, Denton, Christopher, Fonseca, Carmen, Assassi, Shervin, Zhou, Xiaodong, Mayes, Maureen D, Simeon, Carmen Pilar, Ortego-Centeno, Norberto et al.
DOI: 10.1002/art.38870

A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility.

PMID: 24401602
Journal: ARTHRITIS RES THER
Year: 2014
Reference: Arthritis Res Ther. 2014 Jan 9;16(1):R6. doi: 10.1186/ar4432.
Impact factor: 4.117
Publication type: Paper in international publication
Authors: Castillo, Ma Jesus, Voskuyl, Alexandre E, Shiels, Paul G, van Laar, Jacob M, Fonseca, Carmen, Denton, Christopher, Herrick, Ariane, Worthington, Jane, Assassi, Shervin, Koeleman, Bobby P et al.
DOI: 10.1186/ar4432

Clinical characteristics and one-year survival in heart failure patients more than 85 years of age compared with younger.

PMID: 23385010
Journal: European Journal of Internal Medicine
Year: 2013
Reference: Eur J Intern Med. 2013 Jun;24(4):339-45. doi: 10.1016/j.ejim.2013.01.005. Epub 2013 Feb 4.
Impact factor: 2.049
Publication type: Paper in international publication
Authors: Montero-Perez-Barquero, Manuel, Conde-Martel, Alicia, Formiga, Francesc, Perez-Bocanegra, Carmen, Armengou-Arxe, Arola, Muela-Molinero, Alberto, Sanchez-Sanchez, Cristina, Diez-Manglano, Jesus et al.
DOI: 10.1016/j.ejim.2013.01.005

The epidemiology of anaphylaxis in Europe: a systematic review.

PMID: 24117770
Journal: ALLERGY
Year: 2013
Reference: Allergy. 2013 Nov;68(11):1353-61. doi: 10.1111/all.12272. Epub 2013 Oct 14.
Impact factor: 5.883
Publication type: Review in international publication
Authors: Lack, G, Panesar, S S, Javad, S, de Silva, D, Nwaru, B I, Hickstein, L, Muraro, A, Roberts, G, Worm, M, Bilo, M B et al.
DOI: 10.1111/all.12272

Histiocytoid Sweet syndrome and cutaneous polyarteritis nodosa secondary to myelodysplastic syndrome.

PMID: 24382288
Journal: International Journal of Rheumatic Diseases
Year: 2013
Reference: Int J Rheum Dis. 2013 Dec;16(6):777-9. doi: 10.1111/1756-185X.12103. Epub 2013 Jun 3.
Impact factor: 1.65
Publication type: Letter or abstract
Authors: Pinal-Fernandez, Iago, Ferrer Fabrega, Berta, Ramentol Sintas, Marc, Solans Laque, Roser et al.
DOI: 10.1111/1756-185X.12103

Evidence of association of the NLRP1 gene with giant cell arteritis.

PMID: 23253924
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2013
Reference: Ann Rheum Dis. 2013 Apr;72(4):628-30. doi: 10.1136/annrheumdis-2012-202609. Epub 2012 Dec 19.
Impact factor: 9.111
Publication type: Letter or abstract
Authors: Serrano, Aurora, Carmona, F David, Castaneda, Santos, Solans, Roser, Hernandez-Rodriguez, Jose, Cid, Maria C, Prieto-Gonzalez, Sergio, Miranda-Filloy, Jose A, Rodriguez-Rodriguez, Luis, Morado, Inmaculada C et al.
DOI: 10.1136/annrheumdis-2012-202609

[Use of benzodiazepines according to the admission diagnosis].

PMID: 22995843
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Nov 17;139(12):531-4. doi: 10.1016/j.medcli.2012.05.037. Epub 2012 Sep 17.
Impact factor: 1.385
Publication type: Paper in national publication
Authors: Formiga, Francesc, Duaso, Enric, Ruiz, Domingo, San Jose, Antonio, Urrutia, Agustin, Lopez-Soto, Alfonso et al.
DOI: 10.1016/j.medcli.2012.05.037

A multicentre study on high-frequency ultrasound evaluation of the skin and joints in patients with psoriatic arthritis treated with infliximab.

PMID: 23020866
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2012
Reference: Clin Exp Rheumatol. 2012 Nov-Dec;30(6):879-85. Epub 2012 Dec 17.
Impact factor: 2.148
Publication type: Paper in international publication
Authors: De Agustin, Juan Jose, Moragues, Carmen, De Miguel, Eugenio, Moller, Ingrid, Acebes, Carlos, Naredo, Esperanza, Uson, Jacqueline, Rejon, Eduardo, Mayordomo, Lucia, Garrido, Jesus et al.
DOI:

Bone mass and vitamin D in patients with systemic sclerosis from two Spanish regions.

PMID: 22935485
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2012
Reference: Clin Exp Rheumatol. 2012 Nov-Dec;30(6):905-11. Epub 2012 Dec 17.
Impact factor: 2.148
Publication type: Paper in international publication
Authors: Callejas-Rubio, Jose-Luis, Fernandez-Roldan, Concepcion, Simeon-Aznar, Carmen-Pilar, Garcia-Hernandez, Francisco, Castillo-Garcia, Maria-Jesus, Fonollosa Pla, Vicent, Barnosi Marin, Ana Celia, Gonzalez-Gay, Miguel Angel, Ortego-Centeno, Norberto, Rios-Fernandez, Raquel et al.
DOI:

Evidence that deletion at FCGR3B is a risk factor for systemic sclerosis.

PMID: 22551723
Journal: GENES AND IMMUNITY
Year: 2012
Reference: Genes Immun. 2012 Sep;13(6):458-60. doi: 10.1038/gene.2012.15. Epub 2012 May 3.
Impact factor: 3.872
Publication type: Paper in international publication
Authors: Simeon, C P, Fonollosa, V, Carreira, P E, Ortego-Centeno, N, Gonzalez-Gay, M A, Airo, P, Coenen, M, Martin, J, Radstake, T R D J, Merriman, T R et al.
DOI: 10.1038/gene.2012.15

[Syndrome CINCA/NOMID].

PMID: 21596181
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Jan;136 Suppl 1:10-5. doi: 10.1016/S0025-7753(11)70003-3.
Impact factor: 1.413
Publication type: Paper in national publication
Authors: Modesto, Consuelo et al.
DOI: 10.1016/S0025-7753(11)70003-3

[A 47-year-old woman with progressive dyspnea, cutaneous oedema and muscular weakness].

PMID: 21367434
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Apr 23;136(11):495-500. doi: 10.1016/j.medcli.2010.10.023. Epub 2011 Mar 1.
Impact factor: 1.413
Publication type: Letter or abstract
Authors: Bujan, Segundo, Arguis, Pedro, Grau, Josep Maria et al.
DOI: 10.1016/j.medcli.2010.10.023

Etanercept-induced myelopathy in a pediatric case of blau syndrome.

PMID: 22937436
Journal: Case Rep Rheumatol
Year: 2011
Reference: Case Rep Rheumatol. 2011;2011:134106. doi: 10.1155/2011/134106. Epub 2012 Jan 15.
Impact factor: 0.47
Publication type: Paper in international publication
Authors: Caracseghi, Fabiola, Izquierdo-Blasco, Jaume, Sanchez-Montanez, Angel, Melendo-Perez, Susana, Roig-Quilis, Manuel, Modesto, Consuelo et al.
DOI: 10.1155/2011/134106

A nonsynonymous functional variant of the ITGAM gene is not involved in biopsy-proven giant cell arteritis.

PMID: 21965647
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2011
Reference: J Rheumatol. 2011 Dec;38(12):2598-601. Epub 2011 Oct 1.
Impact factor: 3.551
Publication type: Paper in international publication
Authors: Ortego-Centeno, Norberto, Blanco, Ricardo, de Miguel, Eugenio, Hidalgo-Conde, Ana, Martin, Javier, Gonzalez-Gay, Miguel A, Unzurrunzaga, Ainhoa, Mari-Alfonso, Begona, Sopena, Bernardo, Solans, Roser et al.
DOI: 10.3899/jrheum.110685

[Internet-based Continuing Medical Education. Presentation of the first experience of the Spanish Society of Internal Medicine].

PMID: 20633875
Journal: REVISTA CLINICA ESPANOLA
Year: 2010
Reference: Rev Clin Esp. 2010 Dec;210(11):567-72. doi: 10.1016/j.rce.2010.04.012. Epub 2010 Jul 14.
Impact factor: 0.584
Publication type: Paper in national publication
Authors: San Jose, A, Formiga, F, Lopez Soto, A, Ortiz, J, Tiberio, G, Ollero, M, Valero, J, Ballarin, M et al.
DOI: 10.1016/j.rce.2010.04.012

[Chronic fatigue syndrome: more than fatigue].

PMID: 21322184
Journal: Rev Enferm
Year: 2010
Reference: Rev Enferm. 2010 Dec;33(12):16-9.
Impact factor: 0
Publication type: Paper in national publication
Authors: Royes, Badia, Alvarez, Carballo, Lalinde, Sevillano, Vidal, Llinas, Martin, Alegre et al.
DOI:

DNase1 activity in systemic lupus erythematosus patients with and without nephropathy.

PMID: 19844716
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2010
Reference: Rheumatol Int. 2010 Nov;30(12):1601-4. doi: 10.1007/s00296-009-1199-6. Epub 2009 Oct 21.
Impact factor: 1.327
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1007/s00296-009-1199-6

A European multicenter randomized double-blind placebo-controlled monotherapy clinical trial of milnacipran in treatment of fibromyalgia.

PMID: 20156949
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2010
Reference: J Rheumatol. 2010 Apr;37(4):851-9. Epub 2010 Feb 15.
Impact factor: 3.854
Publication type: Paper in international publication
Authors: Cimmino, M A, Maugars, Y, Mejjad, O, Schalck, R, Rioult, B, Roussel, P, Serra, E, Viel, E, Mazieres, B, Ginies, P et al.
DOI: 10.3899/jrheum.090884

[Nutritional support in the home-based hospitalization setting].

PMID: 19266120
Journal: Nutricion Hospitalaria
Year: 2009
Reference: Nutr Hosp. 2009 Jan-Feb;24(1):93-6.
Impact factor: 1.096
Publication type: Paper in national publication
Authors: Chicharro, L, Planas, M, Perez-Portabella, C, Velez, C, San Jose, A et al.
DOI:

Palmar fascitis and polyarthritis as a paraneoplastic syndrome associated with ovarian carcinoma: a case report.

PMID: 22190980
Journal: BMJ case reports
Year: 2009
Reference: BMJ Case Rep. 2009;2009. pii: bcr05.2009.1899. doi: 10.1136/bcr.05.2009.1899. Epub 2009 Dec 22.
Impact factor: 0
Publication type: Paper in international publication
Authors: Bolibar, Esther Pages, Raya, Judith Sanchez, Simeon, Carmen-Pilar, Montesinos, Lluisa, Jou, Nuria, Cuxart, Ampar et al.
DOI: 10.1136/bcr.05.2009.1899

Learning and reliability of colour Doppler ultrasound in giant cell arteritis.

PMID: 19646347
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2009
Reference: Clin Exp Rheumatol. 2009 Jan-Feb;27(1 Suppl 52):S53-8.
Impact factor: 2.364
Publication type: Paper in international publication
Authors: De Miguel, E, Lluch, P, Luna, C, Martin, J A, Martinez, E, Mateo, L, Medeiros, D, Mediavilla, M J, Mera, A, Minguez, S et al.
DOI:

Patients' perceptions of health-related quality of life in rheumatoid arthritis.

PMID: 19562403
Journal: CLINICAL RHEUMATOLOGY
Year: 2009
Reference: Clin Rheumatol. 2009 Oct;28(10):1157-65.
Impact factor: 1.559
Publication type: Paper in international publication
Authors: Oriach, M R, Trabado, C, Ordonez, S, Llopart, E, Clavaguera, T, Nunez, Montserrat, Nunez, Esther, Sanchez, Alex, del Val, Jose Luis, Bonet, Maria et al.
DOI: 10.1007/s10067-009-1215-y

Stress neuropeptides evoke epithelial responses via mast cell activation in the rat colon.

PMID: 18691825
Journal: PSYCHONEUROENDOCRINOLOGY
Year: 2008
Reference: Psychoneuroendocrinology. 2008 Oct;33(9):1248-56. doi: 10.1016/j.psyneuen.2008.07.002. Epub 2008 Aug 8.
Impact factor: 4.422
Publication type: Paper in international publication
Authors: Vicario, Maria, Alonso, Carmen, Perdue, Mary H, Guilarte, Mar, Yates, Derrick, Santos, Javier et al.
DOI: 10.1016/j.psyneuen.2008.07.002

Maladaptive intestinal epithelial responses to life stress may predispose healthy women to gut mucosal inflammation.

PMID: 18455999
Journal: GASTROENTEROLOGY
Year: 2008
Reference: Gastroenterology. 2008 Jul;135(1):163-172.e1. doi: 10.1053/j.gastro.2008.03.036. Epub 2008 Mar 22.
Impact factor: 11.673
Publication type: Paper in international publication
Authors: Alonso, Carmen, Guilarte, Mar, Vicario, Maria, Ramos, Laura, Ramadan, Ziad, Antolin, Maria, Martinez, Cristina, Rezzi, Serge, Saperas, Esteban, Kochhar, Sunil et al.
DOI: 10.1053/j.gastro.2008.03.036

Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum.

PMID: 17005763
Journal: GUT
Year: 2007
Reference: Gut. 2007 Feb;56(2):203-9. doi: 10.1136/gut.2006.100594. Epub 2006 Sep 27.
Impact factor: 9.002
Publication type: Paper in international publication
Authors: Guilarte, Mar, Santos, Javier, de Torres, Ines, Alonso, Carmen, Vicario, Maria, Ramos, Laura, Martinez, Cristina, Casellas, Francesc, Saperas, Esteban, Malagelada, Juan Ramon et al.
DOI: 10.1136/gut.2006.100594

Targeting mast cells in the treatment of functional gastrointestinal disorders.

PMID: 16956793
Journal: CURRENT OPINION IN PHARMACOLOGY
Year: 2006
Reference: Curr Opin Pharmacol. 2006 Dec;6(6):541-6. doi: 10.1016/j.coph.2006.08.001. Epub 2006 Sep 7.
Impact factor: 5.366
Publication type: Editorail in international publication
Authors: Alonso, Carmen, Malagelada, Juan Ramon, Vicario, Maria, Guilarte, Mar, Santos, Javier et al.
DOI: 10.1016/j.coph.2006.08.001

Anisakis simplex-induced small bowel obstruction after fish ingestion: preliminary evidence for response to parenteral corticosteroids.

PMID: 16206499
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Ga
Year: 2005
Reference: Clin Gastroenterol Hepatol. 2005 Jul;3(7):667-71. doi: 10.1016/s1542-3565(05)00363-0.
Impact factor: 0
Publication type: Paper in international publication
Authors: Malagelada, Juan Ramon, Santos, Javier, Guilarte, Mar, Alonso, Carmen, Ramos, Laura, Vilaseca, Jaime et al.
DOI: 10.1016/s1542-3565(05)00363-0

Pathogenesis of irritable bowel syndrome: the mast cell connection.

PMID: 15764142
Journal: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Year: 2005
Reference: Scand J Gastroenterol. 2005 Feb;40(2):129-40. doi: 10.1080/00365520410009410.
Impact factor: 1.824
Publication type: Editorail in international publication
Authors: Malagelada, J R, Alonso, Carmen, Guilarte, Mar, Santos, Javier et al.
DOI: 10.1080/00365520410009410

Thesis

Estudio de una cohorte de pacientes con esclerodermia y neoplasia: incidencia, tipos de cáncer y factores de riesgo.

PhD student: Maria Roca Herrera
Director/s: Carmen Pilar Simeón i Aznar, Alfredo Guillen Del Castillo
University: Universitat Autònoma de Barcelona
Year: 2023

Síndrome de Behçet: estudio de microcirculación e inmunotrombosis y correlación fenotípica, de Joan Maria Mercadé Torras

PhD student: Joan María Mercadé Torras
Director/s: Roser Solans Laque, Segundo Bujan Rivas
University: Universitat Autònoma de Barcelona
Year: 2022

Implicación de las alteraciones capilaroscópicas basales y de seguimiento en el pronóstico y la progresión de la esclerodermia sistémica

PhD student: Serafín Alonso Vila
Director/s: Carmen Pilar Simeón i Aznar, Albert Selva O'Callaghan, Alfredo Guillen Del Castillo
University: Universitat Autònoma de Barcelona
Year: 2022

Utilitat de L´ecografia doppler carotídea a la quantificació del risc cardiovascular en pacients amb esclerodèrmia

PhD student: Isidro Sanz Pérez
Director/s: Fernando Martínez Valle, Carmen Pilar Simeón i Aznar
University: Universitat Autònoma de Barcelona
Year: 2022

Biomarcadors diagnòstics i d'activitat a la Síndrome de Sjögren Primari

PhD student: Jose Loureiro Amigo, Jose Loureiro Amigo
Director/s: Roser Solans Laque
University: Universitat Autònoma de Barcelona
Year: 2022

Características clínicas y de laboratorio de la patología obstétrica relacionada con los anticuerpos antifosfolipídicos.

PhD student: Enrique Esteve Valverde
Director/s: Jaume Alijotas Reig
University: Universidad Autònoma de Barcelona
Year: 2021

Factores predictivos de respuesta a inmunoterapia en cáncer colorrectal avanzado con inestabilidad de microsatélites.

PhD student: Núria Mulet Margalef
Director/s: Albert Selva O'Callaghan
University: Universidad Autònoma de Barcelona
Year: 2021

Evaluación inmunogénica de los tumores de mama triple negativos en relación a la presencia o no de linfocitos intratumorales

PhD student: Angela Quintana Vega
Director/s: Javier Cortés Castan, Eva Muñoz Couselo, Vicente Peg Camara
University: Universidad Autònoma de Barcelona
Year: 2019

Evaluación de la efectividad de una intervención basada en la disminución de las horas de sedestación en pacientes con sobrepeso y obesidad moderada (proyecto SEDESTACTIV)

PhD student: María Elena Martínez Ramos
Director/s: Albert Selva O'Callaghan
University: Universidad Autònoma de Barcelona
Year: 2019

Efectividad de una intervención multifactorial para la modificación de parámetros de fragilidad en población anciana

PhD student: Romera Liebana Laura
Director/s: Albert Selva O'Callaghan
University: Universidad Autònoma de Barcelona
Year: 2019

Diagnóstico de los pacientes con alergia a gamba

PhD student: Maria Rueda García
Director/s: Albert Selva O'Callaghan
University: Universidad Autònoma de Barcelona
Year: 2019

Caracteristicas epidemiológicas de una gran cohorte de pacientes con enfermedades mediadas por mecanismos autoinmunes

PhD student: Ana Carolina Díaz Mendoza, Ana Carolina Díaz Mendoza, Ana Carolina Díaz Mendoza
Director/s: Sara Marsal Barril, Maria America Lopez Lasanta
University: Universidad Autònoma de Barcelona
Year: 2018

Fenotipos de alergia alimentaria por sensibilización a proteínas transferidoras de lípidos (LTP) en adultos del área mediterránea

PhD student: Núria Moreno Pérez
Director/s: Moisés Labrador Horrillo, Olga Luengo Sanchez
University: Universidad Autònoma de Barcelona
Year: 2018

Comorbilidad como factor predisponente a fiebre neutropénica o infección documentada en los pacientes con linfoma sometidos a tratamiento con quimioterapia

PhD student: Ana Jaqueline Bañuelos Ávila
Director/s: Jaume Alijotas Reig, Isabel Ruiz Camps
University: Universidad Autònoma de Barcelona
Year: 2018

Desenvolupament d'un model predictiu amb marcadors tumorals per a descartar malignitat en pacients amb pèrdua de pes involuntària aïllada en una Unitat de diagnòstic ràpid

PhD student: Jordi Aligue Capsada
Director/s: Antonio San Jose Laporte
University: Universidad Autònoma de Barcelona
Year: 2018

Estudio de la afección pulmonar asociada a Esclerodermia Sistémica: biomarcadores pronósticos y detección precoz

PhD student: Alfredo Guillen Del Castillo
Director/s: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Miguel Vilardell Tarres, Miguel Vilardell Tarres
University: Universidad Autònoma de Barcelona
Year: 2017

Factores predictores de la incapacidad laboral en el sindrome de fatiga crónica

PhD student: Mònica Faro Colomés
Director/s: José Alegre Martin
University: Universidad Autònoma de Barcelona
Year: 2017

Artritis idiopáticajuvenil: estudio de la incidencia y prevalencia en Catalunya.

PhD student: Basilio Rodriguez Diez
Director/s: Consuelo Modesto Caballero, Albert Selva O'Callaghan
University: Universidad Autònoma de Barcelona
Year: 2010

Senecio jacobea: caracterización de una nueva fuente alergénica.

PhD student: Olga Luengo Sanchez, Olga Luengo Sanchez
Director/s: José Ángel Bosch Gil, Victòria Cardona Dahl, José Ángel Bosch Gil
University: Universidad Autònoma de Barcelona
Year: 2008

Actividad serica de la DNasa1 en pacientes afectos de lupus eritematoso sistémico.

PhD student: Fernando Martínez Valle, Fernando Martínez Valle
Director/s:
University: Universidad Autònoma de Barcelona
Year: 2007

Modulació de la resposta immunològica per la immunoteràpia amb Dermatophagoides pteronyssinus. Relació amb l'eficàcia clínica

PhD student: Victòria Cardona Dahl, Victòria Cardona Dahl
Director/s:
University: Universidad Autònoma de Barcelona
Year: 2002

Blog

News

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.

The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.

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Graduated Researcher Systemic Autoimmune Diseases Group_20240174
Start date:
23/05/2024
End date:
06/06/2024
Document: Download
Research Technician Systemic Autoimmune Diseases Research Group – Microbioma Research Group
Start date:
15/12/2023
End date:
10/01/2024
Document: Download
Study Coordinator Allergology Department
Start date:
03/11/2023
End date:
23/11/2023
Document: Download