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ESTUDIO EN FASE II, MULTICÉNTRICO, ALEATORIZADO, ABIERTO Y DE GRUPOS PARALELOS PARA EVALUAR LA BIOEQUIVALENCIA DE DOS FORMULACIONES SUBCUTÁNEAS DE OCRELIZUMAB EN PACIENTES CON ESCLEROSIS MÚLTIPLE

  • Protocol code: CN45320
  • EudraCT code: No aplica
  • Pathology: Malalties del sistema nerviós
  • Principal investigator:  Montalban Gairín, Xavier
  • Research group:  Neuroimmunologia clínica
  • Service: Neuroimmunologia
  • Phase: Fase II
  • Recruiting: Closed
  • Status: Iniciat

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
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Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

“Estudio de fase III, aleatorizado, doble ciego y controlado con placebo de Pasritamig (JNJ-78278343), un fármaco que redirige los linfocitos T y actúa sobre la calicreína humana 2, en combinación con el mejor tratamiento de soporte frente al mejor tratamiento de soporte para el cáncer de próstata metastásico resistente a la castración”

  • Protocol code: 78278343PCR3001
  • EudraCT code: No aplica
  • Pathology: Tumors
  • Principal investigator:  Valderrama Rodríguez, Angelica
  • Service: Sense classificar
  • Phase: Fase III
  • Recruiting: Open
  • Status: Open

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
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Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
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Protocolo maestro para un estudio de plataforma de fase II, abierto, con varios fármacos, multicéntrico, para evaluar la seguridad, tolerabilidad, farmacocinética y actividad antitumoral preliminar de fármacos novedosos o combinaciones como tratamiento perioperatorio en participantes con adenocarcinoma gastroesofágico resecable localmente avanzado (GEMINI-PeriOp GC)

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Phase 3 Randomized, Double-blind, Placebo controlled Study to Evaluatethe Efficacy and Safety of Maridebart Cafraglutide on Mortality and Morbidity inParticipants Living With Heart Failure With Preserved or Mildly Reduced Ejection Fractionand Obesity (MARITIME-HF)]

  • Protocol code: 20230227
  • EudraCT code: No aplica
  • Pathology: Malalties del sistema circulatori
  • Principal investigator:  Soriano Colomé, Toni
  • Research group:  Malalties cardiovasculars
  • Service: Cardiologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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A Phase 1/1b Study of ASP2138 as Monotherapy and in Combination with Pembrolizumab and mFOLFOX6 or Ramucirumab and Paclitaxel in Participants with Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma and in Combination with mFOLFIRINOX in Participants with Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma Whose Tumors Have Claudin (CLDN) 18.2 Expression

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Células dendríticas tolerogénicas autólogas (ATDC) para receptores de trasplantes renales altamente sensibilizados

  • Protocol code: ATDC-PICI
  • EudraCT code: No aplica
  • Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més
  • Principal investigator:  Moreso Mateos, Francesc
  • Research group:  Nefrologia i trasplantament renal
  • Service: Nefrologia
  • Phase: Phase I
  • Recruiting: Closed
  • Status: Open

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Estudio de fase 3, aleatorizado, doble ciego y con doblesimulación para evaluar la eficacia y la seguridad del empasiprubart intravenoso frentea inmunoglobulina intravenosa en adultos con polineuropatía desmielinizanteinflamatoria crónica

  • Protocol code: ARGX-117-2401
  • EudraCT code: No aplica
  • Pathology: Nervous system diseases
  • Principal investigator:  Juntas Morales, Raul
  • Research group:  Sistema nerviós perifèric
  • Service: Neurologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants with Atherosclerotic Cardiovascular Disease and Overweight or Obesity (MARITIME-CV)

  • Protocol code: 20220196
  • EudraCT code: No aplica
  • Pathology: Circulatory system diseases
  • Principal investigator:  Ciudin Mihai, Andreea
  • Research group:  Diabetis i metabolisme
  • Service: Endocrinologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio de fase 2b/3, adaptativo, aleatorizado y controlado con principio activo, para evaluar la eficacia, seguridad y tolerabilidad del povetacicept frente a un inhibidor de la calcineurina en el tratamiento de la nefropatía membranosa primaria

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Ensayo global de fase IIb, aleatorizado, doble ciego y controladocon placebo para evaluar la eficacia y la seguridad del ninerafaxstat en pacientes concardiomiopatía hipertrófica obstructiva sintomática – FORTITUDE-HCM

  • Protocol code: IMB101-010
  • EudraCT code: No aplica
  • Pathology: Circulatory system diseases
  • Principal investigator:  Limeres Freire, Javier
  • Research group:  Cardiovascular Diseases
  • Service: Cardiology
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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Ensayo clínico de fase III, aleatorizado, doble ciego, controlado con placebo, multicéntrico y con un período de extensión para evaluar la eficacia y la seguridad de inyecciones de Xeomin® para la prevención de la migraña crónica.

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A Phase Ill double-blind, randomised, parallel-group superioritytrial to evaluate efficacy and safety of the combined use of oral vicadrostat (Bl 690517)and empagliflozin compared with placebo and empagliflozin in participants with type 2diabetes, hypertension and established cardiovascular disease.

  • Protocol code: 1378-0041
  • EudraCT code: No aplica
  • Pathology: Circulatory system diseases
  • Principal investigator:  Lozano Torres, Jordi
  • Research group:  Cardiovascular Diseases
  • Service: Cardiology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio de fase II, multicéntrico, aleatorizado y abierto de JSB462 (luxdegalutamida) en combinación con lutecio (177Lu) vipivotida tetraxetano en pacientes varones adultos con cáncer de próstata metastásico resistente a la castración PSMA positivo.

  • Protocol code: CJSB462B12201
  • EudraCT code: No aplica
  • Pathology: Tumors
  • Principal investigator:  Valderrama Rodríguez, Angelica
  • Service: Unclassified
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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A Phase 1/1b Study of IAM1363 in Participants with Advanced Cancers Harboring HER2 Alterations

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Estudio en fase II, aleatorizado, controlado con placebo conenmascaramiento doble y con comparador activo en abierto, de grupos paralelos ymulticéntrico para evaluar la eficacia, la seguridad y la tolerabilidad de RO7795081administrado una vez al día durante 30 semanas a participantes con diabetes mellitusde tipo 2

  • Protocol code: BP45703
  • EudraCT code: No aplica
  • Pathology: Malalties endocrines, nutricionals i metabòliques
  • Principal investigator:  Ciudin Mihai, Andreea
  • Research group:  Diabetes and Metabolism
  • Service: Endocrinology
  • Phase: Phase II
  • Recruiting: Open
  • Status: Open

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[A Randomized, Double-Blind, Active-Controlled Multicenter Phase 2Study Evaluating the Efficacy and Safety of ALG-000184 Compared with TenofovirDisoproxil Fumarate in Untreated HBeAg-Positive and HBeAg-Negative Adult Subjectswith Chronic Hepatitis B Virus Infection (B-SUPREME).]

  • Protocol code: ALG-000184-202
  • EudraCT code: No aplica
  • Pathology: Malalties del sistema digestiu
  • Principal investigator:  Buti Ferret, Maria
  • Research group:  Malalties hepàtiques
  • Service: Hepatologia
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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Ensayo clínico de extensión abierto de vormatrigina en pacientesadultos con epilepsia

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ESTUDIO DE FASE III, MULTICÉNTRICO, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO Y DE GRUPOS PARALELOS PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE TRONTINEMAB EN PARTICIPANTES CON ENFERMEDAD DE ALZHEIMER (EA) SINTOMÁTICA TEMPRANA (DE DETERIORO COGNITIVO LEVE A DEMENCIA LEVE POR EA)

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Ensayo clínico de fase III, aleatorizado, doble ciego, controlado con placebo, multicéntrico y con un período de extensión para evaluar la eficacia y la seguridad de inyecciones de Xeomin® para la prevención de la migraña episódica.

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Estudio de fase III para investigar la eficacia y la seguridad delorforgliprón administrado una vez al día en participantes con obesidad o sobrepeso ygonartrosis: ensayo multicéntrico, aleatorizado, doble ciego, con grupos paralelos ycomparativo con placebo (ATTAIN-OA PAIN)

  • Protocol code: J2A-MC-GZPT
  • EudraCT code: No aplica
  • Pathology: Endocrine, nutritional and metabolic diseases
  • Principal investigator:  Ciudin Mihai, Andreea
  • Research group:  Diabetes and Metabolism
  • Service: Endocrinology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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