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Gerard Cantero Recasens

I am a Principal Investigator of the Renal Physiopathology Group at Vall d'Hebron Research Institute (VHIR) in Barcelona. Motivated by my deep interest in understanding how ion signalling impacts cellular homeostasis and its pathological implications, I have cultivated over the years a diverse skill set including electrophysiology, biochemistry, live-cell imaging, molecular biology, and cell biology. My primary research focus lies in unravelling the intricate relationship between ion homeostasis, glycosylation, and protein trafficking under both physiological and pathological conditions, with a particular emphasis on renal diseases.

Instituciones de las que forman parte

Investigador/a principal
Fisiopatología Renal
Vall Hebron Institut de Recerca

Gerard Cantero Recasens

Instituciones de las que forman parte

Investigador/a principal
Fisiopatología Renal
Vall Hebron Institut de Recerca

I am a Principal Investigator of the Renal Physiopathology Group at Vall d'Hebron Research Institute (VHIR) in Barcelona. Motivated by my deep interest in understanding how ion signalling impacts cellular homeostasis and its pathological implications, I have cultivated over the years a diverse skill set including electrophysiology, biochemistry, live-cell imaging, molecular biology, and cell biology. My primary research focus lies in unravelling the intricate relationship between ion homeostasis, glycosylation, and protein trafficking under both physiological and pathological conditions, with a particular emphasis on renal diseases.

I conducted my Ph.D. thesis in Dr. Valverde’s lab (UPF) on the role of different asthma-associated proteins in controlling intracellular Ca2+ levels. During my Ph.D., I collaborated with Dr. von Blume (USA) to identify a new sorting mechanism at the Golgi; and with Dr. Hoth’s Lab (Germany) to hone my electrophysiological Ca2+ measurement techniques. Later, as a postdoctoral researcher in Dr. Malhotra’s lab (CRG), I led a team that unravelled how cells regulate mucins’ quality and quantities. From 2020 to 2022, I served as a senior researcher of the Renal Physiopathology Group (VHIR), where I studied the role of ion channels in rare renal diseases. Recently, I have been a visiting researcher at the Osaka International Cancer Institute, to deepen my knowledge on glycosylation (Japan); and at Leiden University (the Netherlands) to learn renal organoids’ generation.
My expertise in the field of ion channels is shown by my presentations at numerous scientific congresses and my high-impact publications (74 citations/year in the last 5 years). At present, I am director of a Ph.D. thesis and two Master Final Projects. Regarding my teaching experience, currently, I am professor of the Translational Biomedical Research Master at VHIR, where I am also the co-coordinator of the cardiovascular and kidney diseases module.
My involvement in the scientific community also includes being a member of the Dent Disease Foundation Medical Advisory Board (USA), review editor of Frontiers in Cell and Developmental Biology, and national and international grants’ evaluator. Referring to my merits, I was awarded with a Spanish Ph.D. mobility fellowship, the extraordinary Ph.D. award, a Juan de la Cierva fellowship, and a short-term EMBO fellowship. Furthermore, I have secured national and international funding, including grants from the Instituto de Salud Carlos III, the Mizutani Foundation for Glycoscience and the "Sociedad Española Contra el Cáncer".

Proyectos

Unravelling CIC-5 role on glycosylation and its link with proximal tubule functioning

IP: Gerard Cantero Recasens
Colaboradores: -
Entidad financiadora: Mizutani Foundation for Glycoscience
Financiación: 45000
Referencia: MIZUTANI FOUNDATION FOR GLYCOSCIENCE - 2022
Duración: 01/04/2023 - 31/03/2024

Noticias relacionadas

"Pacientes con hipomagnesemia familiar con hipercalciuria y nefrocalcinosis presentan perfiles de miARNs en vesículas extracelulares urinarias asociados a la progresión de la enfermedad" ha sido el trabajo premiado.

Los investigadores del VHIR han realizado un estudio que ha permitido identificar que la proteína ClC-5 regula los niveles de colágeno a través de la vía β-catenina y la degradación lisosomal.

La investigación realizará un análisis funcional de las variantes genéticas modificadoras del fenotipo en pacientes afectados de hipomagnesemia familiar con hipercalciuria y nefrocalcinosis (HFHNC).

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