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Jorge Pagola Pérez Blanca

My daily work involves clinical practice, teaching, and research. As a physician, I am a vascular neurologist, providing hospital care and on-call services. I specialize in cardioembolic stroke, both in its diagnosis and treatment. As an educator, I coordinate training in focused ultrasound at the national and international levels. My field of research has been the diagnosis and treatment of ischemic stroke. In my Doctoral Thesis in 2010 I defended the influence of advanced fibrinolytic treatment in the worst-prognosis stroke, basilar thrombosis. Later, already at the time of the development of thrombectomy, we published the usefulness of stent retrievers and in recent years I collaborated in the achievement and improvement of this type of treatment that has demonstrated the impact on clinical improvement and a reduction in mortality. In recent years, my field of research has focused on the diagnosis of the cause of stroke with advanced techniques, because in my opinion, it did not make sense to continue performing endovascular treatment and not knowing the origin of the stroke in up to 30% of cases. We have developed new diagnostic techniques that have been adapted to our daily clinical practice (wearable Holter, focused echocardiography, analysis of atrial deformability). In recent years, our group has continued to innovate in the detection of atrial fibrillation, now with smart bracelets that empower the patient in their self-care. In this effort to improve diagnosis, we have created a protocol for analyzing the thrombus extracted from acute cerebral occlusion. We have created lines of research to determine, through histological, immunohistochemical and proteomic analysis of the thrombus, the cause of the stroke and the response to both lytic drugs and endovascular therapy. Finally, we have created a new innovative line, cytometry of the thrombus extracted in thrombectomy of acute stroke. A technique that is faster and less expensive than the usual histological analysis and that has been shown to be able to identify thrombi of cardioembolic origin and those most resistant to recanalization.

Instituciones de las que forman parte

Investigador/a principal
Investigación en Ictus
Vall Hebron Institut de Recerca
Ictus y Hemodinámica Cerebral
Hospital General

Jorge Pagola Pérez Blanca

Instituciones de las que forman parte

Investigador/a principal
Investigación en Ictus
Vall Hebron Institut de Recerca
Ictus y Hemodinámica Cerebral
Hospital General

My daily work involves clinical practice, teaching, and research. As a physician, I am a vascular neurologist, providing hospital care and on-call services. I specialize in cardioembolic stroke, both in its diagnosis and treatment. As an educator, I coordinate training in focused ultrasound at the national and international levels. My field of research has been the diagnosis and treatment of ischemic stroke. In my Doctoral Thesis in 2010 I defended the influence of advanced fibrinolytic treatment in the worst-prognosis stroke, basilar thrombosis. Later, already at the time of the development of thrombectomy, we published the usefulness of stent retrievers and in recent years I collaborated in the achievement and improvement of this type of treatment that has demonstrated the impact on clinical improvement and a reduction in mortality. In recent years, my field of research has focused on the diagnosis of the cause of stroke with advanced techniques, because in my opinion, it did not make sense to continue performing endovascular treatment and not knowing the origin of the stroke in up to 30% of cases. We have developed new diagnostic techniques that have been adapted to our daily clinical practice (wearable Holter, focused echocardiography, analysis of atrial deformability). In recent years, our group has continued to innovate in the detection of atrial fibrillation, now with smart bracelets that empower the patient in their self-care. In this effort to improve diagnosis, we have created a protocol for analyzing the thrombus extracted from acute cerebral occlusion. We have created lines of research to determine, through histological, immunohistochemical and proteomic analysis of the thrombus, the cause of the stroke and the response to both lytic drugs and endovascular therapy. Finally, we have created a new innovative line, cytometry of the thrombus extracted in thrombectomy of acute stroke. A technique that is faster and less expensive than the usual histological analysis and that has been shown to be able to identify thrombi of cardioembolic origin and those most resistant to recanalization.

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Proyectos

ESCALA DE RIESGO DE ICTUS EN PACIENTES CON FIBRILACIÓN AURICULAR Y ANTICOAGULANTES ORALES DIRECTOS

IP: Jorge Pagola Pérez Blanca
Colaboradores: José Alvarez Sabin, Noelia Rodríguez Villatoro, Jaume Francisco Pascual, Hug Cuellar Calabria, ESCALA DE RIESGO DE ICTUS EN PACIENTES CON FIBRILACIÓN AURICULAR Y ANTICOAGULANTES ORALES DIRECTOS, Claudia Meza Burgos, Federica Rizzo
Entidad financiadora: Instituto de Salud Carlos III
Financiación: 61250
Referencia: PI24/00333
Duración: 01/01/2025 - 31/12/2027

NexTOLL: A Phase IIb Clinical Trial to evaluate the neuroprotective effect of ApTOLL in stroke patients

IP: Marc Ribó Jacobi
Colaboradores: Marta Aurora Rubiera del Fueyo, Jorge Pagola Pérez Blanca, Carlos Molina Cateriano, Mª Ángeles Muchada López
Entidad financiadora: Ministerio Ciencia, Innovación y Universidades
Financiación: 498435
Referencia: CPP2022-009778
Duración: 09/03/2023 - 03/12/2026

Ministerio de Ciencia

NexTOLL: A Phase IIb Clinical Trial to evaluate the neuroprotective effect of ApTOLL in stroke patients

IP: Marc Ribó Jacobi
Colaboradores: Marta Aurora Rubiera del Fueyo, Jorge Pagola Pérez Blanca, Carlos Molina Cateriano, Mª Ángeles Muchada López
Entidad financiadora: Ministerio de Ciencia e Innovación-MICINN
Financiación: 498435
Referencia: CPP2022-009778
Duración: 09/03/2023 - 08/03/2026

Ministerio de Ciencia

VALIDACIÓN DIAGNÓSTICA DE UNA PULSERA INTELIGENTE PARA LA DETECCIÓN DE FIBRIL

IP: Jorge Pagola Pérez Blanca
Colaboradores: Nuria Rivas Gandara, José Alvarez Sabin, Jaume Francisco Pascual
Entidad financiadora: Instituto de Salud Carlos III
Financiación: 85910
Referencia: PI20/01210
Duración: 01/01/2021 - 30/06/2025

Noticias relacionadas

La financiación permitirá a la compañía, surgida en el entorno de Vall d'Hebron, completar el desarrollo clínico de su tecnología y avanzar hacia su llegada a los pacientes.

El proyecto RECUPERA, liderado por DyCare y Ephion Health en colaboración con Vall d'Hebron, Eurecat y Fundació Ictus, combinará IA, visión artificial y sensores biomecánicos para medir la evolución de los pacientes y adaptar ejercicios a sus necesidades.

Se ha logrado financiación para 43 proyectos en las convocatorias de Proyectos de I+D+I en Salud, Desarrollo Tecnológico en Salud e Investigación Clínica Independiente

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