About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
PMID: 37973633 Journal: EUROPEAN RADIOLOGY Year: 2023 Reference: Eur Radiol. 2023 Nov 16. doi: 10.1007/s00330-023-10416-6. Impact factor: Publication type: Editorail in international publication Authors: Arntzen, Ellen Christin; Coote, Susan; Jonsdottir, Johanna; Kalron, Alon; Kos, Daphne; Learmonth, Yvonne C; Moumdjian, Lousin; Nedeljkovic, Una; Novotna, Klara; Pareto, Deborah et al. DOI: 10.1007/s00330-023-10416-6
PMID: 37961530 Journal: Year: 2023 Reference: medRxiv. 2023 Oct 24:2023.10.23.23297397. doi: 10.1101/2023.10.23.23297397. Preprint. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Albasha, Hasan; Alexandri, Nektaria; Andreassi, Maria Grazia; Bianco, Lisa; Bissell, Malenka M; Body, Simon C; Brieva, Luis; Brochet, Bruno; Caffarelli, Anthony; Carlisle, Steven G et al. DOI: 10.1101/2023.10.23.23297397
PMID: 37992310 Journal: CLINICAL CANCER RESEARCH Year: 2023 Reference: Clin Cancer Res. 2023 Nov 22. doi: 10.1158/1078-0432.CCR-23-0133. Impact factor: Publication type: Paper in international publication Authors: Abdel-Mannan, Omar; Barbash, Olena; Cescon, David W; Champsas, Dimitrios; Chitre, Manali; Ciccarelli, Olga; Desai, Ishita; Dhar, Arindam; Forsyth, Rob; Hacohen, Yael et al. DOI: 10.1158/1078-0432.CCR-23-0133
PMID: 38033284 Journal: JOURNAL OF CLINICAL ONCOLOGY Year: 2023 Reference: J Clin Oncol. 2023 Nov 30:JCO2300897. doi: 10.1200/JCO.23.00897. Impact factor: Publication type: Paper in international publication Authors: Abdalkader, Mohamad; Bautista Sirvent, Francisco J; Bertrand, Yves; Beverloo, Berna H; Bourquin, Jean-Pierre; Brivio, Erica; Bui, Jenny; Bukowinski, Andrew; Cooper, Stacy; de Havenon, Adam et al. DOI: 10.1200/JCO.23.00897
PMID: 36001711 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2022 Reference: N Engl J Med. 2022 Aug 25;387(8):704-714. doi: 10.1056/NEJMoa2201904. Impact factor: Publication type: Paper in international publication Authors: Adamczyk-Sowa, Monika; Alekseenko, Yuri; Alifirova, Valentina; Alvarez, Enrique; Alvarez, Enrique; Arefyeva, Elena; Arroyo Gonzalez, Rafael; Bakhtiyarova, Klara; Belova, Anna; Bernitsas, Evanthia et al. DOI: 10.1056/NEJMoa2201904
PMID: 34927702 Journal: REVISTA DE NEUROLOGIA Year: 2022 Reference: Rev Neurol. 2022 Jan 1;74(1):22-34. doi: 10.33588/rn.7401.2021163. Impact factor: 0.87 Publication type: Review in national publication Authors: Sepulveda, M; Arrambide, G; Cobo-Calvo, A et al. DOI: 10.33588/rn.7401.2021163
PMID: 34850641 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):16-28. doi: 10.1177/13524585211059766. Epub 2021 Dec 1. Impact factor: 6.312 Publication type: Paper in international publication Authors: Coetzee, Timothy; Zaratin, Paola; Strum, Jon; Smith, Kathryn E; Thompson, Alan J; Carroll, William; Ciccarelli, Olga; Comi, Giancarlo; Cross, Anne; Donnelly, Alexis et al. DOI: 10.1177/13524585211059766
PMID: 33764197 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jan;28(1):132-138. doi: 10.1177/13524585211005339. Epub 2021 Mar 25. Impact factor: 6.312 Publication type: Paper in international publication Authors: Portaccio, Emilio; Fonderico, Mattia; Hemmer, Bernhard; Derfuss, Tobias; Stankoff, Bruno; Selmaj, Krzysztof; Tintore, Mar; Amato, Maria Pia et al. DOI: 10.1177/13524585211005339
PMID: 33327838 Journal: Multiple Sclerosis Journal Year: 2021 Reference: Mult Scler. 2021 Aug;27(9):1455-1457. doi: 10.1177/1352458520980141. Epub 2020 Dec 17. Impact factor: 6.312 Publication type: Paper in international publication Authors: Comabella, Manuel, Deutschmann, Claudia, Midaglia, Luciana, Schierack, Peter, Martinez, Julia, Roggenbuck, Dirk, Montalban, Xavier et al. DOI: 10.1177/1352458520980141
PMID: 34338742 Journal: JAMA Neurology Year: 2021 Reference: JAMA Neurol. 2021 Sep 1;78(9):1099-1107. doi: 10.1001/jamaneurol.2021.2385. Impact factor: 18.302 Publication type: Paper in international publication Authors: Requena, Manuel, Olive-Gadea, Marta, Muchada, Marian, Hernandez, David, Rubiera, Marta, Boned, Sandra, Pinana, Carlos, Deck, Matias, Garcia-Tornel, Alvaro, Diaz-Silva, Humberto et al. DOI: 10.1001/jamaneurol.2021.2385
PMID: 34293826 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2021 Reference: Eur J Neurol. 2021 Dec;28(12):4124-4134. doi: 10.1111/ene.15030. Epub 2021 Aug 5. Impact factor: 6.089 Publication type: Paper in international publication Authors: Cardenas-Robledo, Simon, Otero-Romero, Susana, Passarell-Bacardit, Maria Angels, Carbonell-Mirabent, Pere, Sastre-Garriga, Jaume, Montalban, Xavier, Tintore, Mar et al. DOI: 10.1111/ene.15030
PMID: 34273945 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 Jul 17;22(1):75. doi: 10.1186/s10194-021-01289-5. Impact factor: 7.277 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Pareto, Deborah, Gallardo, Victor J, Cuberas-Borros, Gemma, Alpuente, Alicia, Caronna, Edoardo, Vila-Ballo, Adria, Lorenzo-Bosquet, Carles, Castell-Conesa, Joan, Rovira, Alex et al. DOI: 10.1186/s10194-021-01289-5
PMID: 31610739 Journal: Multiple Sclerosis Journal Year: 2020 Reference: Mult Scler. 2020 Nov;26(13):1658-1669. doi: 10.1177/1352458519877810. Epub 2019 Oct 15. Impact factor: 5.649 Publication type: Paper in international publication Authors: Arevalo, Maria Jesus, Anglada, Elisenda, Menendez, Rebeca, Midaglia, Luciana, Galan, Ingrid, Vidal-Jordana, Angela, Castillo, Joaquin, Mulero, Patricia, Zabalza, Ana, Rodriguez-Acevedo, Breogan et al. DOI: 10.1177/1352458519877810
PMID: 33066917 Journal: Journal of Stroke & Cerebrovascular Diseases Year: 2020 Reference: J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105225. doi: 10.1016/j.jstrokecerebrovasdis.2020.105225. Epub 2020 Aug 5. Impact factor: 1.787 Publication type: Paper in international publication Authors: Ribo, Marc, Molina, Carlos A, Tomasello, Alejandro, Rubiera, Marta, Requena, Manuel, Muchada, Marian, Garcia-Tornel, Alvaro, Deck, Matias, Juega, Jesus, Boned, Sandra et al. DOI: 10.1016/j.jstrokecerebrovasdis.2020.105225
PMID: 32881954 Journal: PLoS One Year: 2020 Reference: PLoS One. 2020 Sep 3;15(9):e0238301. doi: 10.1371/journal.pone.0238301. eCollection 2020. Impact factor: 2.74 Publication type: Paper in international publication Authors: Cobo-Calvo, Alvaro, Ruiz, Anne, Richard, Chloe, Blondel, Sandrine, Cavagna, Sylvie, Strazielle, Nathalie, Ghersi-Egea, Jean-Francois, Giraudon, Pascale, Marignier, Romain et al. DOI: 10.1371/journal.pone.0238301
PMID: 32868418 Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Year: 2020 Reference: Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22962-22966. doi: 10.1073/pnas.2006117117. Epub 2020 Aug 31. Impact factor: 9.412 Publication type: Paper in international publication Authors: Biegon, Anat, Alia-Klein, Nelly, Alexoff, David L, Fowler, Joanna S, Kim, Sung Won, Logan, Jean, Pareto, Deborah, Preston-Campbell, Rebecca, Wang, Gene-Jack, Hildebrandt, Tom et al. DOI: 10.1073/pnas.2006117117
PMID: 29400912 Journal: JOURNAL OF NEUROIMAGING Year: 2018 Reference: J Neuroimaging. 2018 May;28(3):313-319. doi: 10.1111/jon.12500. Epub 2018 Feb 5. Impact factor: 1.953 Publication type: Paper in international publication Authors: Rovira, Alex, Renom, Marta, Pareto, Deborah, Sastre-Garriga, Jaume, Alonso, Juli, Galan, Ingrid, Arevalo, Maria Jesus, Montalban, Xavier et al. DOI: 10.1111/jon.12500
PMID: 29177546 Journal: JOURNAL OF NEUROLOGY Year: 2018 Reference: J Neurol. 2018 Jan;265(1):32. doi: 10.1007/s00415-017-8679-5. Impact factor: 3.783 Publication type: Letter or abstract Authors: Alenda, Raquel, Costa-Frossard, Lucienne, Alvarez-Lafuente, Roberto, Espejo, Carmen, Rodriguez-Martin, Eulalia, Sainz de la Maza, Susana, Villarrubia, Noelia, Rio, Jordi, Dominguez-Mozo, Maria I, Alvarez-Cermeno, Jose C et al. DOI: 10.1007/s00415-017-8679-5
PMID: 29027004 Journal: JOURNAL OF NEUROLOGY Year: 2018 Reference: J Neurol. 2018 Jan;265(1):24-31. doi: 10.1007/s00415-017-8625-6. Epub 2017 Oct 12. Impact factor: 3.783 Publication type: Paper in international publication Authors: Villar, Luisa M, Alvarez-Cermeno, Jose C, Montalban, Xavier, Dominguez-Mozo, Maria I, Alenda, Raquel, Costa-Frossard, Lucienne, Alvarez-Lafuente, Roberto, Espejo, Carmen, Rodriguez-Martin, Eulalia, de la Maza, Susana Sainz et al. DOI: 10.1007/s00415-017-8625-6
PMID: 29251340 Journal: REVISTA DE NEUROLOGIA Year: 2018 Reference: Rev Neurol. 2018 Jan 1;66(1):25-32. Impact factor: 0.601 Publication type: Review in national publication Authors: Midaglia, L, Mora, L, Mulero, P, Sastre-Garriga, J, Montalban, X et al. DOI: 10.33588/rn.6601.2017213
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
