About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
PMID: 37841069 Journal: Brain communications Year: 2023 Reference: Brain Commun. 2023 Oct 4;5(5):fcad255. doi: 10.1093/braincomms/fcad255. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Barkhof, Frederik; Brownlee, Wallace; Castano, Carlos; Chard, Declan; Chung, Karen; Ciccarelli, Olga; Dominguez, Carlos; Gandini Wheeler-Kingshott, Claudia A M; Gramegna, Laura Ludovica; Haider, Lukas et al. DOI: 10.1093/braincomms/fcad255
PMID: 37841253 Journal: Frontiers in Immunology Year: 2023 Reference: Front Immunol. 2023 Sep 29;14:1248182. doi: 10.3389/fimmu.2023.1248182. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Aladro, Yolanda; Alia, Eva Maria Guerra; Alvarez-Lafuente, Roberto; Arroyo, Rafael; Baurain, Jean-Francois; Braicu, Elena Ioana; Casanova-Peno, Ignacio; Colombo, Nicoletta; Comabella, Manuel; Costa-Frossard, Lucienne et al. DOI: 10.3389/fimmu.2023.1248182
PMID: 37850411 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2023 Reference: J Investig Allergol Clin Immunol. 2023 Oct 18:0. doi: 10.18176/jiaci.0941. Impact factor: Publication type: Paper in international publication Authors: Aladro, Yolanda; Alvarez-Lafuente, Roberto; Arroyo, Rafael; Casanova-Peno, Ignacio; Comabella, Manuel; Costa-Frossard, Lucienne; Cruz, M J; Dominguez-Mozo, Maria Inmaculada; Espejo, D; Garcia-Dominguez, Jose Manuel et al. DOI: 10.18176/jiaci.0941
PMID: 37850363 Journal: Future Oncology Year: 2023 Reference: Future Oncol. 2023 Oct 18. doi: 10.2217/fon-2023-0282. Impact factor: Publication type: Paper in international publication Authors: Barkhof, Frederik; Bokemeyer, Carsten; Brownlee, Wallace; Chard, Declan; Chung, Karen; Ciardiello, Fortunato; Ciccarelli, Olga; Dubreuil, Olivier; Esser, Regina; Gandini Wheeler-Kingshott, Claudia A M et al. DOI: 10.2217/fon-2023-0282
PMID: 34994579 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jul;28(8):1277-1285. doi: 10.1177/13524585211061861. Epub 2022 Jan 7. Impact factor: Publication type: Paper in international publication Authors: Ascherio, Alberto; Barkhof, Frederik; Cortese, Marianna; Edan, Gilles; Freedman, Mark S; Hartung, Hans-Peter; Kappos, Ludwig; Manuel Escobar, Juan; Montalban, Xavier; Munger, Kassandra L et al. DOI: 10.1177/13524585211061861
PMID: 34994577 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jun;28(7):1131-1137. doi: 10.1177/13524585211061343. Epub 2022 Jan 7. Impact factor: Publication type: Paper in international publication Authors: Bermel, Robert A; Cohen, Jeffrey A; Grossman, Cynthia I; Hersh, Carrie M; Hyland, Megan; Montalban, Xavier; Mowry, Ellen M; Naismith, Robert; Naylor, Maria L; Nicholas, Jacqueline et al. DOI: 10.1177/13524585211061343
PMID: 34988947 Journal: ACTA NEUROLOGICA BELGICA Year: 2022 Reference: Acta Neurol Belg. 2022 Jun;122(3):823-825. doi: 10.1007/s13760-021-01864-2. Epub 2022 Jan 6. Impact factor: Publication type: Letter or abstract Authors: Auger, Cristina; Callejo, Ana; Cobo-Calvo, Alvaro; Lallana, Sofia; Rio, Jordi; Sanchez-Tejerina, Daniel et al. DOI: 10.1007/s13760-021-01864-2
PMID: 34596743 Journal: JOURNAL OF NEUROLOGY Year: 2022 Reference: J Neurol. 2022 Jan;269(1):452-459. doi: 10.1007/s00415-021-10823-z. Epub 2021 Oct 1. Impact factor: Publication type: Paper in international publication Authors: Arrambide, Georgina; Auger, Cristina; Castillo, Joaquim; Cobo, Alvaro; Comabella, Manuel; Galan, Ingrid; Gasperini, Claudio; Midaglia, Luciana; Montalban, Xavier; Nos, Carlos et al. DOI: 10.1007/s00415-021-10823-z
PMID: 33625280 Journal: Multiple Sclerosis Journal Year: 2021 Reference: Mult Scler. 2021 Apr;27(5):661-662. doi: 10.1177/1352458520981309. Epub 2021 Feb 24. Impact factor: Publication type: Paper in international publication Authors: Tur, Carmen et al. DOI: 10.1177/1352458520981309
PMID: 33882422 Journal: NeuroImage-Clinical Year: 2021 Reference: Neuroimage Clin. 2021;30:102659. doi: 10.1016/j.nicl.2021.102659. Epub 2021 Apr 6. Impact factor: 4.881 Publication type: Paper in international publication Authors: Simoes, Jorge, Ruggieri, Serena, Schregel, Katharina, Ropele, Stefan, Rocca, Maria A, Gasperini, Claudio, Gallo, Antonio, Schoonheim, Menno M, Amann, Michael, Yiannakas, Marios et al. DOI: 10.1016/j.nicl.2021.102659
PMID: 34857668 Journal: Journal of NeuroInterventional Surgery Year: 2021 Reference: J Neurointerv Surg. 2021 Dec 2. pii: neurintsurg-2021-018241. doi: 10.1136/neurintsurg-2021-018241. Impact factor: 5.836 Publication type: Paper in international publication Authors: Olive-Gadea, Marta, Requena, Manuel, Diaz, Facundo, Boned, Sandra, Garcia-Tornel, Alvaro, Muchada, Marian, Deck, Matias, Lozano, Prudencio, Rodriguez-Villatoro, Noelia, Juega, Jesus et al. DOI: 10.1136/neurintsurg-2021-018241
PMID: 34859704 Journal: Multiple Sclerosis Journal Year: 2021 Reference: Mult Scler. 2021 Dec 3:13524585211061339. doi: 10.1177/13524585211061339. Impact factor: 6.312 Publication type: Paper in international publication Authors: Rovira, Alex, Corral, Juan Francisco, Auger, Cristina, Valverde, Sergi, Vidal-Jordana, Angela, Ng Wong, Yiken Karelys, Tintore, Mar, Pareto, Deborah, Aymerich, Francesc Xavier, Montalban, Xavier et al. DOI: 10.1177/13524585211061339
PMID: 31978348 Journal: CELL Year: 2020 Reference: Cell. 2020 Jan 23;180(2):403. doi: 10.1016/j.cell.2020.01.002. Impact factor: Publication type: Letter or abstract Authors: Agliardi, Cristina; Alfredsson, Lars; Andlauer, Till F M; Ban, Maria; Baranzini, Sergio E; Barcellos, Lisa F; Barizzone, Nadia; Bayas, Antonios; Beecham, Ashley H; Bergh, Florian Then et al. DOI: 10.1016/j.cell.2020.01.002
PMID: 31943361 Journal: NEUROUROLOGY AND URODYNAMICS Year: 2020 Reference: Neurourol Urodyn. 2020 Feb;39(2):762-770. doi: 10.1002/nau.24276. Epub 2020 Jan 15. Impact factor: Publication type: Paper in international publication Authors: Adot, Jose Maria; Allue, Marta; Arlandis, Salvador; Blasco, Pedro; Casanova, Bonaventura; Lopez-Fando, Luis; Madurga, Blanca; Matias-Guiu, Jorge; Medina-Polo, Jose; Meza-Murillo, Edwin-Roger et al. DOI: 10.1002/nau.24276
PMID: 31936765 Journal: Cells Year: 2020 Reference: Cells. 2020 Jan 10;9(1). pii: cells9010175. doi: 10.3390/cells9010175. Impact factor: Publication type: Paper in international publication Authors: Aktas, Orhan; Alloza, Iraide; Altmann, Vivian; Antiguedad, Alfredo; Astobiza, Ianire; Buttmann, Mathias; Castillo-Trivino, Tamara; Chan, Andrew; Comabella, Manuel; Espino-Paisan, Laura et al. DOI: 10.3390/cells9010175
PMID: 31734402 Journal: AUTOIMMUNITY REVIEWS Year: 2020 Reference: Autoimmun Rev. 2020 Jan;19(1):102429. doi: 10.1016/j.autrev.2019.102429. Epub 2019 Nov 15. Impact factor: Publication type: Review in international publication Authors: Adan, Alfredo; Borruel, Natalia; Canete, Juan D; Dauden, Esteban; Garcia-Vidal, Carolina; Gonzalez-Gay, Miguel Angel; Juanatey, Carlos Gonzalez; Martin, Antonio Olveira; Martin, Esther Holgado; Montalban, Xavier et al. DOI: 10.1016/j.autrev.2019.102429
PMID: 30587519 Journal: NEUROLOGY Year: 2019 Reference: Neurology. 2019 Feb 5;92(6):296-298. doi: 10.1212/WNL.0000000000006801. Epub 2018 Dec 26. Impact factor: 8.689 Publication type: Paper in international publication Authors: Pappolla, Agustin, Midaglia, Luciana, Boix Rodriguez, Claudia P, Puig, Adaia Albasanz, Lung, Maiylyi, Camps, Isabel Ruiz, Castillo, Joaquin, Mulero, Patricia, Arrambide, Georgina, Rodriguez-Acevedo, Breogan et al. DOI: 10.1212/WNL.0000000000006801
PMID: 30687923 Journal: REVISTA DE NEUROLOGIA Year: 2019 Reference: Rev Neurol. 2019 Feb 1;68(3):132-133. Impact factor: 0.485 Publication type: Letter whit IF Authors: Llaurado-Gayete, A, Campos-Fernandez, D, Olive-Gadea, M, Ballve-Martin, A, Rio, J, Rovira, A, Santamarina, E et al. DOI: 10.33588/rn.6803.2018377
PMID: 30623863 Journal: Multiple Sclerosis and Related Disorders Year: 2019 Reference: Mult Scler Relat Disord. 2019 Feb;28:230-234. doi: 10.1016/j.msard.2019.01.007. Epub 2019 Jan 3. Impact factor: 2.725 Publication type: Paper in international publication Authors: Sepulveda, Maria, Armangue, Thais, Sabater, Lidia, Martinez-Hernandez, Eugenia, Arrambide, Georgina, Blanco, Yolanda, Llufriu, Sara, Martinez-Lapiscina, Elena H, Mulero, Patricia, Sola-Valls, Nuria et al. DOI: 10.1016/j.msard.2019.01.007
PMID: 30035845 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2019 Reference: Eur J Neurol. 2019 Jan;26(1):41-50. doi: 10.1111/ene.13760. Epub 2018 Sep 9. Impact factor: 4.387 Publication type: Paper in international publication Authors: Kopke, Sascha, Giordano, Andrea, Veronese, Simone, Rahn, Anne Christin, Kleiter, Ingo, Basedow-Rajwich, Birgit, Fornari, Arianna, Battaglia, Mario Alberto, Drulovic, Jelena, Kooij, Liesbeth et al. DOI: 10.1111/ene.13760
PMID: 29117789 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Oct;24(11):1507-1510. doi: 10.1177/1352458517739137. Epub 2017 Nov 9. Impact factor: 5.28 Publication type: Paper in international publication Authors: Malhotra, Sunny, Sorosina, Melissa, Rio, Jordi, Peroni, Silvia, Midaglia, Luciana, Villar, Luisa M, Alvarez-Cermeno, Jose C, Schroeder, Ina, Esposito, Federica, Clarelli, Ferdinando et al. DOI: 10.1177/1352458517739137
PMID: 28445084 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 May;24(6):721-727. doi: 10.1177/1352458517707070. Epub 2017 Apr 26. Impact factor: 5.28 Publication type: Paper in international publication Authors: Huerga, Elena, Mitjana, Raquel, Auger, Cristina, Tintore, Mar, Rovira, Alex, Montalban, Xavier, Otero-Romero, Susana, Arrambide, Georgina, Pareto, Deborah, Vidal-Jordana, Angela et al. DOI: 10.1177/1352458517707070
PMID: 29774057 Journal: Therapeutic Advances in Neurological Disorders Year: 2018 Reference: Ther Adv Neurol Disord. 2018 May 10;11:1756286418773025. doi: 10.1177/1756286418773025. eCollection 2018. Impact factor: 4.75 Publication type: Review in international publication Authors: Mulero, Patricia, Midaglia, Luciana, Montalban, Xavier et al. DOI: 10.1177/1756286418773025
PMID: 29671675 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Oct;24(11):1516-1517. doi: 10.1177/1352458518771259. Epub 2018 Apr 19. Impact factor: 5.28 Publication type: Editorail in international publication Authors: Rio, Jordi, Rodriguez-Acevedo, Breogan et al. DOI: 10.1177/1352458518771259
PMID: 25778697 Journal: Multiple Sclerosis Journal Year: 2015 Reference: Mult Scler. 2015 Dec;21(14):1802-10. doi: 10.1177/1352458515575338. Epub 2015 Mar 16. Impact factor: 4.822 Publication type: Paper in international publication Authors: Simon, Eva, Castillo, Joaquin, Palavra, Filipe, Mitjana, Raquel, Auger, Cristina, Rovira, Alex, Montalban, Xavier, Vidal-Jordana, Angela, Galan, Ingrid, Nos, Carlos et al. DOI: 10.1177/1352458515575338
PMID: 26185778 Journal: Neurology: Neuroimmunology & Neuroinflammation Year: 2015 Reference: Neurol Neuroimmunol Neuroinflamm. 2015 Jul 2;2(4):e132. doi: 10.1212/NXI.0000000000000132. eCollection 2015 Aug. Impact factor: Publication type: Letter or abstract Authors: Perez-Miralles, Francisco Carlos, Sastre-Garriga, Jaume, Vidal-Jordana, Angela, Rio, Jordi, Auger, Cristina, Pareto, Deborah, Tintore, Mar, Rovira, Alex, Montalban, Xavier et al. DOI: 10.1212/NXI.0000000000000132
PMID: 26204085 Journal: REVISTA DE NEUROLOGIA Year: 2015 Reference: Rev Neurol. 2015 Aug 16;61(4):145-52. Impact factor: 0.83 Publication type: Clinical guide Authors: Rio, Jordi, Gobartt, Ana L, Ramio-Torrenta, Ll, Munteis-Olivas, E, Perez-Trullen, J M, Bujanda-Alegria, M, Solar-Sanchez, D M, Menendez-Gonzalez, M, Marey-Lopez, J, Llaneza-Gonzalez, M A et al. DOI:
PMID: 26445728 Journal: Neurology: Neuroimmunology & Neuroinflammation Year: 2015 Reference: Neurol Neuroimmunol Neuroinflamm. 2015 Sep 24;2(5):e154. eCollection 2015 Oct. Impact factor: Publication type: Letter or abstract Authors: Bustamante, Marta F, Morcillo-Suarez, Carlos, Malhotra, Sunny, Rio, Jordi, Leyva, Laura, Fernandez, Oscar, Zettl, Uwe K, Killestein, Joep, Brassat, David, Garcia-Merino, Juan Antonio et al. DOI: 10.1212/NXI.0000000000000154
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
