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Clinical Research/Innovation in Pneumonia & Sepsis (CRIPS)

CRIPS is a research group focusing on severe acute respiratory infections and sepsis. 

The objective is to develop projects on clinical and translational research in hospital-acquired pneumonia, community-acquired pneumonia, and severe viral respiratory infections, such as influenza and COVID-19. CRIPS also develop epidemiological studies focused on risk and prognostic factors for multi-resistant pathogens, validation of ventilator-associated events in ventilated adult and pediatric patients, incorporating artificial intelligence techniques. It also highlights evidence-based medicine (EBM) research, evaluating therapies and prevention strategies and participating in the formulation of clinical practice guidelines, as part of CIBERES and the European Society for Clinical Microbiology and Infections. The EBM research focuses on knowledge translation to get research findings to the point of decision making, providing health-related recommendations, focusing on clinical research and relevance of care. 

CRIPS collaborate on a Local (UIC, IDIAP), National (CIBERES), and International level (CHU Nimes, Uolo University, ISARIC and Pneumo-Inspire Networks).

Publications

Differences between genetic dilated cardiomyopathy and myocarditis in children presenting with severe cardiac dysfunction.

PMID: 34286374
Journal: EUROPEAN JOURNAL OF PEDIATRICS
Year: 2022
Reference: Eur J Pediatr. 2022 Jan;181(1):287-294. doi: 10.1007/s00431-021-04175-z. Epub 2021 Jul 20.
Impact factor: 3.183
Publication type: Paper in international publication
Authors: Fernandez-Alvarez, Paula, Codina-Sola, Marta, Balcells, Joan, Izquierdo-Blasco, Jaume, Gran, Ferran, Garrido, Marta, Dolader, Paola, Fidalgo, Andrea, Navarro, Alexandra, Sabate-Rotes, Anna et al.
DOI: 10.1007/s00431-021-04175-z

Transverse orange nail lesions following SARS-CoV-2 infection.

PMID: 33340203
Journal: Dermatologic Therapy
Year: 2021
Reference: Dermatol Ther. 2021 Jan;34(1):e14688. doi: 10.1111/dth.14688. Epub 2020 Dec 22.
Impact factor: 2.851
Publication type: Letter or abstract
Authors: Tammaro, Antonella, Adebanjo, Ganiyat Adenike Ralitsa, Erasmus, Hans-Peter, Chello, Camilla, Pezzuto, Aldo, Ramirez-Estrada, Sergio, Rello, Jordi et al.
DOI: 10.1111/dth.14688

Nebulized antibiotics for ventilator-associated pneumonia: methodological framework for future multicenter randomized controlled trials.

PMID: 33605620
Journal: CURRENT OPINION IN INFECTIOUS DISEASES
Year: 2021
Reference: Curr Opin Infect Dis. 2021 Apr 1;34(2):156-168. doi: 10.1097/QCO.0000000000000720.
Impact factor: 4.915
Publication type: Review in international publication
Authors: Torres, Antoni, Zhu, Yinggang, Pugin, Jerome, Rello, Jordi, Rouby, Jean-Jacques, Monsel, Antoine et al.
DOI: 10.1097/QCO.0000000000000720

Cutaneous Endothelial Dysfunction and Complement Deposition in COVID-19.

PMID: 33055532
Journal: AMERICAN JOURNAL OF DERMATOPATHOLOGY
Year: 2021
Reference: Am J Dermatopathol. 2021 Mar 1;43(3):237-238. doi: 10.1097/DAD.0000000000001825.
Impact factor: 1.533
Publication type: Paper in international publication
Authors: Tammaro, Antonella, Adebanjo, Ganiyat Adenike Ralitsa, Del Nonno, Franca, Pezzuto, Aldo, Ramirez-Estrada, Sergio, Parisella, Francesca Romana, Rello, Jordi, Scarabello, Alessandra et al.
DOI: 10.1097/DAD.0000000000001825

Anxiety among front-line health-care workers supporting patients with COVID-19: A global survey.

PMID: 33418193
Journal: GENERAL HOSPITAL PSYCHIATRY
Year: 2021
Reference: Gen Hosp Psychiatry. 2021 Jan-Feb;68:90-96. doi: 10.1016/j.genhosppsych.2020.12.010. Epub 2020 Dec 20.
Impact factor: 3.238
Publication type: Paper in international publication
Authors: Cag, Yasemin, Erdem, Hakan, Gormez, Aynur, Ankarali, Handan, Hargreaves, Sally, Ferreira-Coimbra, Joao, Rubulotta, Francesca, Belliato, Mirko, Berger-Estilita, Joana, Pelosi, Paolo et al.
DOI: 10.1016/j.genhosppsych.2020.12.010

Determinants of empirical antipseudomonal antibiotic prescription for adults with pneumonia in the emergency department.

PMID: 32245452
Journal: BMC Pulmonary Medicine
Year: 2020
Reference: BMC Pulm Med. 2020 Apr 3;20(1):83. doi: 10.1186/s12890-020-1115-0.
Impact factor: 2.813
Publication type: Paper in international publication
Authors: Monso, Eduard, Angrill, Nuria, Gallego, Miguel, Font, Juli, Valles, Jordi, Moron, Anisi, Rello, Jordi et al.
DOI: 10.1186/s12890-020-1115-0

A novel id-iri score: development and internal validation of the multivariable community acquired sepsis clinical risk prediction model.

PMID: 31823148
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2020
Reference: Eur J Clin Microbiol Infect Dis. 2020 Apr;39(4):689-701. doi: 10.1007/s10096-019-03781-y. Epub 2019 Dec 10.
Impact factor: 2.837
Publication type: Paper in international publication
Authors: Diktas, Husrev, Uysal, Serhat, Erdem, Hakan, Cag, Yasemin, Miftode, Egidia, Durmus, Gul, Ulu-Kilic, Aysegul, Alabay, Selma, Szabo, Balint Gergely, Alexandru, Crisan et al.
DOI: 10.1007/s10096-019-03781-y

Parvovirus B19 Myocarditis: Looking Beyond the Heart.

PMID: 31335286
Journal: PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
Year: 2020
Reference: Pediatr Dev Pathol. 2020 Mar-Apr;23(2):158-162. doi: 10.1177/1093526619865641. Epub 2019 Jul 23.
Impact factor: 0.885
Publication type: Paper in international publication
Authors: Izquierdo-Blasco, Jaume, Salcedo Allende, Maria Teresa, Codina Grau, Maria Gemma, Gran, Ferran, Martinez Saez, Elena, Balcells, Joan et al.
DOI: 10.1177/1093526619865641

Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients-a randomized clinical trial.

PMID: 32131866
Journal: CRITICAL CARE
Year: 2020
Reference: Crit Care. 2020 Mar 4;24(1):74. doi: 10.1186/s13054-020-2792-z.
Impact factor: 6.407
Publication type: Paper in international publication
Authors: Schneider, Hauke, Kanesa-Thasan, Niranjan, Eder-Lingelbach, Susanne, Klingler, Anton, Dubischar, Katrin, Wressnigg, Nina, Rello, Jordi, Sramek, Vladimir, Hejja, Maria, Schaaf, Bernhard et al.
DOI: 10.1186/s13054-020-2792-z

An international perspective on hospitalized patients with viral community-acquired pneumonia.

PMID: 30401576
Journal: European Journal of Internal Medicine
Year: 2019
Reference: Eur J Intern Med. 2019 Feb;60:54-70. doi: 10.1016/j.ejim.2018.10.020. Epub 2018 Nov 4.
Impact factor: 3.66
Publication type: Paper in international publication
Authors: Ceccato, Adrian, Radovanovic, Dejan, Sotgiu, Giovanni, Jankovic, Mateja, Mahesh, Padukudru Anand, Marcos, Pedro Jorge, Abdalla, Mohamed I, Di Pasquale, Marta Francesca, Gramegna, Andrea, Terraneo, Silvia et al.
DOI: 10.1016/j.ejim.2018.10.020

Elaboration of consensus clinical endpoints to evaluate antimicrobial treatment efficacy in future HABP/VABP clinical trials.

PMID: 30722013
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2019
Reference: Clin Infect Dis. 2019 Nov 13;69(11):1912-1918. doi: 10.1093/cid/ciz093.
Impact factor: 9.055
Publication type: Paper in international publication
Authors: Rello, Jordi, Rex, John H, Shorr, Andrew F, Talbot, George H, Thamlikitkul, Visanu, Torres, Antoni, Wunderink, Richard G, Timsit, Jean-Francois, Prokocimer, Philippe, Poulakou, Garyphallia et al.
DOI: 10.1093/cid/ciz093

A global priority list of the TOp TEn resistant Microorganisms (TOTEM) study at intensive care: a prioritization exercise based on multi-criteria decision analysis.

PMID: 30426331
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):319-323. doi: 10.1007/s10096-018-3428-y. Epub 2018 Nov 13.
Impact factor: 2.591
Publication type: Paper in international publication
Authors: Wunderink, Richard G, Conway-Morris, Andrew, Rojas, Jose Nicolas, Alp, Emine, Zhang, Zhongheng, Alves, Joana, Lagunes, Leo, Kalwaje Eshwara, Vandana, Rello, Jordi et al.
DOI: 10.1007/s10096-018-3428-y

The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?

PMID: 30680576
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 Apr;38(4):637-647. doi: 10.1007/s10096-019-03486-2. Epub 2019 Jan 24.
Impact factor: 2.591
Publication type: Review in national publication
Authors: Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey, Rello, Jordi et al.
DOI: 10.1007/s10096-019-03486-2

Pneumonia and lung ultrasound in the intensive care unit.

PMID: 24638338
Journal: CHEST
Year: 2014
Reference: Chest. 2014 Mar 1;145(3 Suppl):171A. doi: 10.1378/chest.1806646.
Impact factor: 7.132
Publication type: Paper in international publication
Authors: Parra, Ana, Perez, Purificacion, Serra, Joaquim, Roca, Oriol, Masclans, Joan Ramon, Rello, Jordi et al.
DOI: 10.1378/chest.1806646

Impact of the 2009 influenza A H1N1 pandemic on invasive pneumococcal disease in adults.

PMID: 24456230
Journal: SCAND J INFECT DIS
Year: 2014
Reference: Scand J Infect Dis. 2014 Mar;46(3):185-92. doi: 10.3109/00365548.2013.867072. Epub 2014 Jan 24.
Impact factor: 1.64
Publication type: Paper in international publication
Authors: Ardanuy, Carmen, Pedro-Botet, M Luisa, Burgos, Joaquin, Lujan, Manel, Gimenez, Montse, Rello, Jordi, Planes, Ana, Fontanals, Dionisia, Casas, Irma, Mateu, Lourdes et al.
DOI: 10.3109/00365548.2013.867072

[Diaphragmatic defect, congenital heart disease, agonadism: a new case of PAGOD syndrome.]

PMID: 24582125
Journal: AN PEDIATR
Year: 2014
Reference: An Pediatr (Barc). 2014 Dec;81(6):e34-5. doi: 10.1016/j.anpedi.2013.11.009. Epub 2014 Feb 26.
Impact factor: 0.722
Publication type: Letter whit IF
Authors: Gil, L, Sanchez-de-Toledo, J, Ferreres, J C, Vendrell, T, Ruiz-Campillo, C W, Balcells, J et al.
DOI: 10.1016/j.anpedi.2013.11.009

Risk factors for respiratory failure in pneumococcal pneumonia. The importance of pneumococcal serotypes.

PMID: 23845720
Journal: EUR RESPIR J
Year: 2014
Reference: Eur Respir J. 2014 Feb;43(2):545-53. doi: 10.1183/09031936.00050413. Epub 2013 Jul 11.
Impact factor: 7.125
Publication type: Paper in international publication
Authors: M Planes, Ana, Puig, Mireia, Rello, Jordi, Falco, Vicenc, Pahissa, Albert, Bermudo, Guadalupe, Fontanals, Dionisia, Lujan, Manel, Burgos, Joaquin, Larrosa, M Nieves et al.
DOI: 10.1183/09031936.00050413

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.

PMID: 23353941
Journal: CRITICAL CARE MEDICINE
Year: 2013
Reference: Crit Care Med. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af.
Impact factor: 6.124
Publication type: Paper in international publication
Authors: Resende, Ederlon, Rhodes, Andrew, Annane, Djillali, Gerlach, Herwig, Opal, Steven M, Sevransky, Jonathan E, Sprung, Charles L, Douglas, Ivor S, Jaeschke, Roman, Osborn, Tiffany M et al.
DOI: 10.1097/CCM.0b013e31827e83af

The impact of lung transplantation on ICU personnel.

PMID: 23398845
Journal: Medicina Intensiva
Year: 2013
Reference: Med Intensiva. 2013 Apr;37(3):206-8. doi: 10.1016/j.medin.2012.12.003. Epub 2013 Feb 9.
Impact factor: 1.323
Publication type: Paper in national publication
Authors: Rello, J, Masnou, N et al.
DOI: 10.1016/j.medin.2012.12.003

Role of biomarkers in the differential diagnosis of acute respiratory failure in the immediate postoperative period of lung transplantation.

PMID: 23462428
Journal: Medicina Intensiva
Year: 2013
Reference: Med Intensiva. 2013 Aug-Sep;37(6):416-22. doi: 10.1016/j.medin.2013.01.005. Epub 2013 Feb 22.
Impact factor: 1.323
Publication type: Paper in national publication
Authors: Sacanell, J, Roman, A, Ruano, L, Rello, J et al.
DOI: 10.1016/j.medin.2013.01.005

Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors.

PMID: 23358539
Journal: INTENSIVE CARE MEDICINE
Year: 2013
Reference: Intensive Care Med. 2013 Apr;39(4):672-81. doi: 10.1007/s00134-012-2808-5. Epub 2013 Jan 29.
Impact factor: 5.258
Publication type: Paper in international publication
Authors: Martin-Loeches, Ignacio, Deja, Maria, Dimopoulos, George, Marsh, Brian, Torres, Antonio, Niederman, Michael S, Rello, Jordi, Koulenti, Despoina et al.
DOI: 10.1007/s00134-012-2808-5

Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection.

PMID: 21107529
Journal: INTENSIVE CARE MEDICINE
Year: 2011
Reference: Intensive Care Med. 2011 Feb;37(2):272-83. Epub 2010 Nov 24.
Impact factor: 4.996
Publication type: Paper in international publication
Authors: Valentin, Andreas, Balasini, Carina, Barahona, Diego, Marsh, Brian, Silva, Eliezer, Flaaten, Haans, Sigurdsson, Gisli, Ivana, Zykova, Cerny, Vladimir, Quintel, Michael et al.
DOI: 10.1007/s00134-010-2078-z

Quality of life, pulmonary function, and tomographic scan abnormalities after ARDS.

PMID: 21330382
Journal: CHEST
Year: 2011
Reference: Chest. 2011 Jun;139(6):1340-6. Epub 2011 Feb 17.
Impact factor: 6.519
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1378/chest.10-2438

What is new in the prevention of ventilator-associated pneumonia?

PMID: 21326100
Journal: CURRENT OPINION IN PULMONARY MEDICINE
Year: 2011
Reference: Curr Opin Pulm Med. 2011 May;17(3):155-9.
Impact factor: 2.906
Publication type: Paper in international publication
Authors: , , et al.
DOI: 10.1097/MCP.0b013e328344db65

Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicentre study.

PMID: 21324159
Journal: CRITICAL CARE
Year: 2011
Reference: Crit Care. 2011;15(1):R62. Epub 2011 Feb 16.
Impact factor: 4.595
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1186/cc10036

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