About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37896223 Journal: Pharmaceutics Year: 2023 Reference: Pharmaceutics. 2023 Oct 14;15(10):2463. doi: 10.3390/pharmaceutics15102463. Impact factor: Publication type: Paper in international publication Authors: Abasolo, Ibane; Agarwal, Neeraj; Andrade, Fernanda; Azad, Arun A; Chakrabarti, Jayeta; Chen, Hsiang-Chun; Fizazi, Karim; Genesca, Joan; Gil, Mar; Hide, Diana et al. DOI: 10.3390/pharmaceutics15102463
PMID: 37892611 Journal: Journal of Clinical Medicine Year: 2023 Reference: J Clin Med. 2023 Oct 11;12(20):6471. doi: 10.3390/jcm12206471. Impact factor: Publication type: Paper in international publication Authors: Abe, Hiroshi; Ahn, Sang Bong; Aldea-Perona, Ana; An, Jihyun; Arai, Taeang; Atsukawa, Masanori; Avendano-Sola, Cristina; Blasco Quilez, Maria Rosario; Bonilla-Toyos, Elvira; Bosch Ferrer, Montserrat et al. DOI: 10.3390/jcm12206471
PMID: 37916574 Journal: LIVER INTERNATIONAL Year: 2023 Reference: Liver Int. 2023 Nov 2. doi: 10.1111/liv.15776. Impact factor: Publication type: Paper in international publication Authors: Aguilar-Riera, Cristina; Aguilar-Riera, Cristina; Biagetti, Betina; Buti, Maria; Campos-Martorell, Ariadna; Casado, Miguel Angel; Clemente, Maria; Dominguez-Hernandez, Raquel; Esteban, Rafael; Fabregas, Anna et al. DOI: 10.1111/liv.15776
PMID: 37921755 Journal: CLINICAL CANCER RESEARCH Year: 2023 Reference: Clin Cancer Res. 2023 Nov 3. doi: 10.1158/1078-0432.CCR-23-1796. Impact factor: Publication type: Paper in international publication Authors: Bardia, Aditya; Bellet-Ezquerra, Meritxell; Bond, John W; Boni, Valentina; Buti, Maria; Casado, Miguel Angel; Chang, Ching-Wei; Dominguez-Hernandez, Raquel; Eng-Wong, Jennifer; Esteban, Rafael et al. DOI: 10.1158/1078-0432.CCR-23-1796
PMID: 35456274 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 Apr 13;11(8). pii: jcm11082181. doi: 10.3390/jcm11082181. Impact factor: Publication type: Paper in international publication Authors: Almela, Manel; Alonso-Garcia, Pilar; Ayuso, Blanca; Corredoira, Juan; Falces, Carles; Garces-Duran, Rodrigo Vicente; Garcia-Garrote, Fernando; Garcia-Gonzalez, Javier; Garcia-Pais, Maria Jose; Hernandez-Meneses, Marta et al. DOI: 10.3390/jcm11082181
PMID: 35429220 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2022 Reference: Am J Transplant. 2022 Sep;22(9):2283-2284. doi: 10.1111/ajt.17062. Epub 2022 Apr 25. Impact factor: Publication type: Letter or abstract Authors: Campos-Varela, Isabel; Dodge, Jennifer L; Price, Jennifer C; Terrault, Norah A et al. DOI: 10.1111/ajt.17062
PMID: 35434589 Journal: JHEP Reports Year: 2022 Reference: JHEP Rep. 2022 Feb 24;4(5):100462. doi: 10.1016/j.jhepr.2022.100462. eCollection 2022 May. Impact factor: Publication type: Paper in international publication Authors: Aguilera, Antonio; Alados-Arboledas, Juan Carlos; Aldamiz-Echevarria, Teresa; Aleman, Soo; Alonso, Roberto; Andreoni, Massimo; Angelico, Mario; Antequera, Pedro; Anton, Jose Joaquin; Applegate, Tanya et al. DOI: 10.1016/j.jhepr.2022.100462
PMID: 35373449 Journal: CTS-Clinical and Translational Science Year: 2022 Reference: Clin Transl Sci. 2022 Jun;15(6):1544-1555. doi: 10.1111/cts.13276. Epub 2022 Apr 19. Impact factor: Publication type: Paper in international publication Authors: Bilbao, Itxarone; Campos-Varela, Isabel; Caralt, Mireia; Castells, Lluis; Charco, Ramon; Dopazo, Cristina; Garcia, Sonia; Gomez-Gavara, Concepcion; Hidalgo, Ernest; Montoro, Bruno et al. DOI: 10.1111/cts.13276
PMID: 33746085 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Aug;75(2):275-283. doi: 10.1016/j.jhep.2021.02.033. Epub 2021 Mar 18. Impact factor: Publication type: Paper in international publication Authors: Avitabile, Emma; Campos-Varela, Isabel; Castellote, Jose; Castells, Lluis; Colmenero, Jordi; Crespo, Gonzalo; Gines, Pere; Gratacos-Gines, Jordi; Perez-Campuzano, Valeria; Pose, Elisa et al. DOI: 10.1016/j.jhep.2021.02.033
PMID: 33749113 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2021 Reference: Am J Transplant. 2021 Sep;21(9):3148-3156. doi: 10.1111/ajt.16569. Epub 2021 Jul 8. Impact factor: Publication type: Paper in international publication Authors: Brandman, Danielle; Campos-Varela, Isabel; Dodge, Jennifer L; Price, Jennifer C; Terrault, Norah A et al. DOI: 10.1111/ajt.16569
PMID: 32529920 Journal: MEDICAL TEACHER Year: 2021 Reference: Med Teach. 2021 Mar;43(3):358-360. doi: 10.1080/0142159X.2020.1774529. Epub 2020 Jun 12. Impact factor: Publication type: Letter or abstract Authors: Bosch, Xavier; Pericas, Juan M et al. DOI: 10.1080/0142159X.2020.1774529
PMID: 33724244 Journal: TRANSPLANTATION Year: 2021 Reference: Transplantation. 2021 Dec 1;105(12):2528-2537. doi: 10.1097/TP.0000000000003736. Impact factor: Publication type: Review in international publication Authors: Augustin, Salvador; Campos-Varela, Isabel; Gomez-Gavara, Concepcion et al. DOI: 10.1097/TP.0000000000003736
PMID: 32077604 Journal: LIVER INTERNATIONAL Year: 2020 Reference: Liver Int. 2020 Feb;40 Suppl 1:15-21. doi: 10.1111/liv.14367. Impact factor: Publication type: Review in international publication Authors: Buti, Maria; Esteban, Rafael; Riveiro-Barciela, Mar; Roade, Luisa et al. DOI: 10.1111/liv.14367
PMID: 32080253 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Feb 20;10(1):3038. doi: 10.1038/s41598-020-59476-4. Impact factor: Publication type: Paper in international publication Authors: Abrisqueta, Pau; Bosch, Francesc; Buti, Maria; Carreras, Maria Jose; Esteban, Rafael; Farriols, Anna; Gubern, Paula; Riveiro-Barciela, Mar; Roade, Luisa et al. DOI: 10.1038/s41598-020-59476-4
PMID: 31629779 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Mar;72(3):472-480. doi: 10.1016/j.jhep.2019.10.005. Epub 2019 Oct 17. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Buti, Maria; Esteban, Juan Ignacio; Forns, Xavier; Genesca, Joan; Lens, Sabela; Marino, Zoe; Minguez, Beatriz; Pons, Monica; Rodriguez-Tajes, Sergio et al. DOI: 10.1016/j.jhep.2019.10.005
PMID: 31606552 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Mar;72(3):391-400. doi: 10.1016/j.jhep.2019.09.029. Epub 2019 Oct 10. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Bosques-Padilla, Francisco; Chu, Huikuan; Duan, Yi; Hou, Xiaohua; Hube, Bernhard; Jiang, Lu; Lang, Sonja; Liu, Jinyuan; Llorente, Cristina et al. DOI: 10.1016/j.jhep.2019.09.029
PMID: 30223834 Journal: RESPIRATORY RESEARCH Year: 2018 Reference: Respir Res. 2018 Sep 17;19(1):177. doi: 10.1186/s12931-018-0882-0. Impact factor: 3.751 Publication type: Review in international publication Authors: Barrecheguren, Miriam, Gonzalez, Cruz, Miravitlles, Marc et al. DOI: 10.1186/s12931-018-0882-0
PMID: 30176817 Journal: BMC INFECTIOUS DISEASES Year: 2018 Reference: BMC Infect Dis. 2018 Sep 3;18(1):446. doi: 10.1186/s12879-018-3356-6. Impact factor: 2.62 Publication type: Paper in international publication Authors: Domingo, Esteban, Rodriguez-Frias, Francisco, Buti, Maria, Esteban, Rafael, Esteban, Juan Ignacio, Quer, Josep, Perales, Celia, Beach, Nathan M, de Avila, Ana I, Llorens, Meritxell et al. DOI: 10.1186/s12879-018-3356-6
PMID: 30103740 Journal: RESPIRATORY RESEARCH Year: 2018 Reference: Respir Res. 2018 Aug 13;19(1):151. doi: 10.1186/s12931-018-0826-8. Impact factor: 3.751 Publication type: Paper in international publication Authors: Greulich, Timm, Rodriguez-Frias, Francisco, Belmonte, Irene, Miravitlles, Marc, Vogelmeier, Claus F, Klemmer, Andreas et al. DOI: 10.1186/s12931-018-0826-8
PMID: 30059722 Journal: ANTIVIRAL RESEARCH Year: 2018 Reference: Antiviral Res. 2018 Oct;158:34-44. doi: 10.1016/j.antiviral.2018.07.019. Epub 2018 Jul 29. Impact factor: 4.307 Publication type: Review in international publication Authors: Rodriguez-Frias, Francisco, Tabernero, David, Caballero, Andrea, Buti, Maria et al. DOI: 10.1016/j.antiviral.2018.07.019
PMID: 27927921 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2017 Reference: J Clin Microbiol. 2017 Feb;55(2):504-509. doi: 10.1128/JCM.01960-16. Epub 2016 Dec 7. Impact factor: 3.631 Publication type: Paper in international publication Authors: Nieto-Aponte, Leonardo, Quer, Josep, Ruiz-Ripa, Alicia, Tabernero, David, Gonzalez, Carolina, Gregori, Josep, Vila, Marta, Asensio, Miriam, Garcia-Cehic, Damir, Ruiz, Gerardo et al. DOI: 10.1128/JCM.01960-16
PMID: 28468860 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2017 Reference: J Clin Microbiol. 2017 Jul;55(7):2180-2187. doi: 10.1128/JCM.00169-17. Epub 2017 May 3. Impact factor: 3.712 Publication type: Paper in international publication Authors: Laperche, Syria, Sauleda, Silvia, Piron, Maria, Muhlbacher, Annelies, Schennach, Harald, Queiros, Lucinda, Uno, Naoki, Yanagihara, Katsunori, Imdahl, Roland, Hey, Ariann et al. DOI: 10.1128/JCM.00169-17
PMID: NOPMID003 Journal: ICU Management Year: 2017 Reference: ICU Management & Practice 2017:4 Impact factor: 0 Publication type: Paper in international publication Authors: Ferrer Ricard, Juan Carlos Ruiz-Rodriguez, Larrosa Nieves, Llaneras J, Molas Emma, Juanjo Gonzalez-Lopez et al. DOI:
PMID: 27785789 Journal: TRANSFUSION Year: 2017 Reference: Transfusion. 2017 Feb;57(2):244-247. doi: 10.1111/trf.13876. Epub 2016 Oct 26. Impact factor: 3.042 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Sauleda, Silvia, Quer, Josep, Salvador, Fernando, Gregori, Josep, Piron, Maria, Rodriguez-Frias, Francisco, Buti, Maria et al. DOI: 10.1111/trf.13876
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.