About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.
Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.
We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function.
PMID: 33619847 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2021 Reference: Neurogastroenterol Motil. 2021 Jul;33(7):e14101. doi: 10.1111/nmo.14101. Epub 2021 Feb 22. Impact factor: 3.598 Publication type: Paper in international publication Authors: Maclnnes, Jane, Relea, Lucia, MacPherson, Lewis C, Cunningham, Margaret R, Vergara, Patri, Accarino, Anna, Kennedy, Charles, Jimenez, Marcel, Barber, Claudia, Traserra, Sara et al. DOI: 10.1111/nmo.14101
PMID: 33613490 Journal: Frontiers in Microbiology Year: 2021 Reference: Front Microbiol. 2021 Feb 5;12:621280. doi: 10.3389/fmicb.2021.621280. eCollection 2021. Impact factor: 5.64 Publication type: Paper in international publication Authors: Notararigo, Sara, Varela, Encarnacion, Otal, Anna, Cristobo, Ivan, Antolin, Maria, Guarner, Francisco, Prieto, Alicia, Lopez, Paloma et al. DOI: 10.3389/fmicb.2021.621280
PMID: 32993305 Journal: Nutricion Hospitalaria Year: 2021 Reference: Nutr Hosp. 2021 Jan 13;37(Spec No2):34-37. doi: 10.20960/nh.03354. Impact factor: 1.057 Publication type: Letter or abstract Authors: Guarner, Francisco et al. DOI: 10.20960/nh.03354
PMID: 32409590 Journal: GUT Year: 2021 Reference: Gut. 2021 Feb;70(2):319-329. doi: 10.1136/gutjnl-2019-319990. Epub 2020 May 14. Impact factor: 23.059 Publication type: Paper in international publication Authors: Tardon, Adonina, Molina-Montes, Esther, Coscia, Claudia, Gomez-Rubio, Paulina, Fernandez, Alba, Boenink, Rianne, Rava, Marta, Marquez, Mirari, Molero, Xavier, Lohr, Matthias et al. DOI: 10.1136/gutjnl-2019-319990
PMID: 31734402 Journal: AUTOIMMUNITY REVIEWS Year: 2020 Reference: Autoimmun Rev. 2020 Jan;19(1):102429. doi: 10.1016/j.autrev.2019.102429. Epub 2019 Nov 15. Impact factor: 7.767 Publication type: Review in international publication Authors: Ruiz de Morales, Jose Maria G, Puig, Lluis, Dauden, Esteban, Canete, Juan D, Pablos, Jose Luis, Martin, Antonio Olveira, Juanatey, Carlos Gonzalez, Adan, Alfredo, Montalban, Xavier, Borruel, Natalia et al. DOI: 10.1016/j.autrev.2019.102429
PMID: 27087165 Journal: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Year: 2017 Reference: J Gastroenterol Hepatol. 2017 Jan;32(1):53-63. doi: 10.1111/jgh.13417. Impact factor: 3.452 Publication type: Paper in international publication Authors: Gonzalez-Castro, Ana M, Martinez, Cristina, Salvo-Romero, Eloisa, Fortea, Marina, Pardo-Camacho, Cristina, Perez-Berezo, Teresa, Alonso-Cotoner, Carmen, Santos, Javier, Vicario, Maria et al. DOI: 10.1111/jgh.13417
PMID: 27112233 Journal: Scientific Reports Year: 2016 Reference: Sci Rep. 2016 Apr 26;6:25001. doi: 10.1038/srep25001. Impact factor: 5.228 Publication type: Paper in international publication Authors: Gely, Cristina, Santiago, Alba, Pozuelo, Marta, Poca, Maria, Roman, Eva, Campos, David, Sarrabayrouse, Guillaume, Vidal, Silvia, Alvarado-Tapias, Edilmar, Guarner, Francisco et al. DOI: 10.1038/srep25001
PMID: 27077120 Journal: EBioMedicine Year: 2016 Reference: EBioMedicine. 2016 Jan 28;5:135-46. doi: 10.1016/j.ebiom.2016.01.032. eCollection 2016 Mar. Impact factor: 0 Publication type: Paper in international publication Authors: Noguera-Julian, Marc, Rocafort, Muntsa, Guillen, Yolanda, Rivera, Javier, Casadella, Maria, Nowak, Piotr, Hildebrand, Falk, Zeller, Georg, Parera, Mariona, Bellido, Rocio et al. DOI: 10.1016/j.ebiom.2016.01.032
PMID: 26603881 Journal: EUROPEAN JOURNAL OF CLINICAL NUTRITION Year: 2016 Reference: Eur J Clin Nutr. 2016 Feb;70(2):170-4. doi: 10.1038/ejcn.2015.192. Epub 2015 Nov 25. Impact factor: 2.935 Publication type: Paper in international publication Authors: Hernandez, M, Garcia-Peris, P, Velasco, C, de la Cuerda, C, Breton, I, Camblor, M, Guarner, F, Paron, L, Lozano, M A et al. DOI: 10.1038/ejcn.2015.192
PMID: 26874350 Journal: Journal of Crohns & Colitis Year: 2016 Reference: J Crohns Colitis. 2016 Jul;10(7):850-9. doi: 10.1093/ecco-jcc/jjw042. Epub 2016 Feb 13. Impact factor: 6.585 Publication type: Paper in international publication Authors: Perez-Torras, Sandra, Iglesias, Ingrid, Llopis, Marta, Lozano, Juan J, Antolin, Maria, Guarner, Francisco, Pastor-Anglada, Marcal et al. DOI: 10.1093/ecco-jcc/jjw042
A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.
Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.
The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.
