About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 34313394 Journal: Arthritis & Rheumatology Year: 2022 Reference: Arthritis Rheumatol. 2022 Feb;74(2):358-364. doi: 10.1002/art.41931. Epub 2021 Dec 26. Impact factor: 10.995 Publication type: Paper in international publication Authors: Balboni, Imelda, Pak, Katherine, Gil-Vila, Albert, Baucells, Andres, Plotz, Benjamin, Casal-Dominguez, Maria, Derfoul, Assia, Angeles Martinez, Maria, Selva-O'Callaghan, Albert, Sabbagh, Sara et al. DOI: 10.1002/art.41931
PMID: 34779868 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2022 Reference: Rheumatol Int. 2022 Jan;42(1):23-29. doi: 10.1007/s00296-021-05046-4. Epub 2021 Nov 15. Impact factor: 2.631 Publication type: Paper in international publication Authors: Gracia-Ramos, Abraham Edgar, Sen, Parikshit, Gupta, Latika, Lilleker, James B, Aggarwal, Vishwesh, Kardes, Sinan, Milchert, Marcin, Gheita, Tamer, Salim, Babur, Velikova, Tsvetelina et al. DOI: 10.1007/s00296-021-05046-4
PMID: 34632668 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2022 Reference: Eur J Neurol. 2022 Feb;29(2):469-477. doi: 10.1111/ene.15137. Epub 2021 Oct 25. Impact factor: 6.089 Publication type: Paper in international publication Authors: On, Begum Irmak, Vidal, Xavier, Berger, Ursula, Sabate, Monica, Ballarin, Elena, Maisterra, Olga, San-Jose, Antonio, Ibanez, Luisa et al. DOI: 10.1111/ene.15137
PMID: 34377160 Journal: Therapeutic Advances in Musculoskeletal Disease Year: 2021 Reference: Ther Adv Musculoskelet Dis. 2021 Jul 27;13:1759720X211032457. doi: 10.1177/1759720X211032457. eCollection 2021. Impact factor: 5.346 Publication type: Review in international publication Authors: Kuwana, Masataka, Gil-Vila, Albert, Selva-O'Callaghan, Albert et al. DOI: 10.1177/1759720X211032457
PMID: 34359858 Journal: Cells Year: 2021 Reference: Cells. 2021 Jul 4;10(7). pii: cells10071688. doi: 10.3390/cells10071688. Impact factor: 6.6 Publication type: Paper in international publication Authors: Barbera, Joan Albert, Peinado, Victor I, Blanco, Isabel, Garcia-Lucio, Jessica, Del Pozo, Roberto, Garcia, Agustin Roberto, Ferrer, Elisabet, Crespo, Isabel, Rodriguez-Chiaradia, Diego A, Simeon-Aznar, Carmen Pilar et al. DOI: 10.3390/cells10071688
PMID: 34331269 Journal: Molecular Diagnosis & Therapy Year: 2021 Reference: Mol Diagn Ther. 2021 Sep;25(5):563-576. doi: 10.1007/s40291-021-00544-4. Epub 2021 Jul 30. Impact factor: 4.074 Publication type: Review in international publication Authors: Garcia-Foncillas, Jesus, Argente, Jesus, Bujanda, Luis, Cardona, Victoria, Casanova, Bonaventura, Fernandez-Montes, Ana, Horcajadas, Jose A, Iniguez, Andres, Ortiz, Alberto, Pablos, Jose L et al. DOI: 10.1007/s40291-021-00544-4
PMID: 32938573 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2021 Reference: J Investig Allergol Clin Immunol. 2021 Jul 26;31(4):334-336. doi: 10.18176/jiaci.0643. Epub 2020 Sep 15. Impact factor: 7.033 Publication type: Paper in international publication Authors: Labrador-Horrillo, M, Roger, A, Basagana, M, Pineda, F, Lazo, C, Navarro, L et al. DOI: 10.18176/jiaci.0643
PMID: 31996780 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Jan 29;10(1):1415. doi: 10.1038/s41598-020-58400-0. Impact factor: 3.998 Publication type: Paper in international publication Authors: Gomez, Nair Perez, Lopez-Mejias, Raquel, Remuzgo-Martinez, Sara, Genre, Fernanda, Pulito-Cueto, Veronica, Rozas, Sonia M Fernandez, Llorca, Javier, Fernandez, David Iturbe, Cuesta, Victor M Mora, Ortego-Centeno, Norberto et al. DOI: 10.1038/s41598-020-58400-0
PMID: 31995656 Journal: ALLERGY Year: 2020 Reference: Allergy. 2020 Jul;75(7):1672-1688. doi: 10.1111/all.14204. Epub 2020 Mar 22. Impact factor: 8.706 Publication type: Paper in international publication Authors: Fokkens, Wytske J, Bedard, Annabelle, Anto, Josep M, Fonseca, Joao A, Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bindslev-Jensen, Carsten, Bosnic-Anticevich, Sinthia, Cardona, Victoria et al. DOI: 10.1111/all.14204
PMID: 31977447 Journal: Current Opinion in Allergy and Clinical Immunology Year: 2020 Reference: Curr Opin Allergy Clin Immunol. 2020 Jun;20(3):248-252. doi: 10.1097/ACI.0000000000000625. Impact factor: 3.246 Publication type: Review in international publication Authors: Cardona, Victoria, Guilarte, Mar, Labrador-Horrillo, Moises et al. DOI: 10.1097/ACI.0000000000000625
PMID: 31969223 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2020 Reference: Clin Exp Rheumatol. 2020 May-Jun;38 Suppl 125(3):106-114. Epub 2020 Jan 14. Impact factor: 3.319 Publication type: Paper in international publication Authors: Iniesta Arandia, Nerea, Espinosa, Gerard, Tolosa Vilella, Carles, Guillen Del Castillo, Alfredo, Rubio Rivas, Manuel, Freire, Mayka, Vargas Hitos, Jose Antonio, Todoli Parra, Jose Antonio, Rodriguez Carballeira, Monica, Marin Ballve, Adela et al. DOI:
PMID: 31157683 Journal: BLOOD COAGULATION & FIBRINOLYSIS Year: 2019 Reference: Blood Coagul Fibrinolysis. 2019 Jul;30(5):239-242. doi: 10.1097/MBC.0000000000000814. Impact factor: 1.12 Publication type: Paper in international publication Authors: Pardos-Gea, Jose, Martinez, Fernanda, Abrisqueta, Pau, Santamaria, Amparo, Bosch, Francesc et al. DOI: 10.1097/MBC.0000000000000814
PMID: 31151417 Journal: BMC Medical Research Methodology Year: 2019 Reference: BMC Med Res Methodol. 2019 May 31;19(1):112. doi: 10.1186/s12874-019-0746-4. Impact factor: 2.509 Publication type: Paper in international publication Authors: Vilaro, Marta, Cortes, Jordi, Selva-O'Callaghan, Albert, Urrutia, Agustin, Ribera, Josep-Maria, Cardellach, Francesc, Basagana, Xavier, Elmore, Matthew, Vilardell, Miquel, Altman, Douglas et al. DOI: 10.1186/s12874-019-0746-4
PMID: 31138531 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2019 Reference: Ann Rheum Dis. 2019 Jul;78(7):996-1002. doi: 10.1136/annrheumdis-2019-215046. Epub 2019 May 28. Impact factor: 14.299 Publication type: Paper in international publication Authors: Ollier, William E, McHugh, Neil J, Mammen, Andrew L, Betteridge, Zoe E, Tansley, Sarah L, Bowes, John, Vencovsky, Jiri, Deakin, Claire T, Danko, Katalin, Vidya, Limaye et al. DOI: 10.1136/annrheumdis-2019-215046
PMID: 30561765 Journal: HEPATOLOGY Year: 2019 Reference: Hepatology. 2019 Jun;69(6):2701-2703. doi: 10.1002/hep.30464. Epub 2019 Mar 7. Impact factor: 14.971 Publication type: Paper in international publication Authors: Senin, Alicia, Salcedo, Maria-Teresa, Merino-Casabiel, Xavier, Castells, Lluis, Esteban, Rafael, Buti, Maria, Martinez-Valle, Fernando, Gironella, Merche, Riveiro-Barciela, Mar et al. DOI: 10.1002/hep.30464
PMID: 28283766 Journal: CLINICAL RHEUMATOLOGY Year: 2017 Reference: Clin Rheumatol. 2017 Jun;36(6):1401-1406. doi: 10.1007/s10067-017-3594-9. Epub 2017 Mar 10. Impact factor: 2.365 Publication type: Paper in international publication Authors: Pardos-Gea, Jose, Cortes-Hernandez, Josefina, Castro-Marrero, Jesus, Balada, Eva, Ordi-Ros, Jose et al. DOI: 10.1007/s10067-017-3594-9
PMID: 28283274 Journal: MEDICINA CLINICA Year: 2017 Reference: Med Clin (Barc). 2017 Jun 21;148(12):574-575. doi: 10.1016/j.medcli.2017.01.027. Epub 2017 Mar 7. Impact factor: 1.125 Publication type: Paper in national publication Authors: Fernandez-Codina, Andreu, Francisco-Pascual, Jaume, Fonollosa-Pla, Vicent et al. DOI: 10.1016/j.medcli.2017.01.027
PMID: 28277489 Journal: Scientific Reports Year: 2017 Reference: Sci Rep. 2017 Mar 9;7:43953. doi: 10.1038/srep43953. Impact factor: 4.259 Publication type: Paper in international publication Authors: Ramentol-Sintas, Marc, Gomez-Vaquero, Carmen, Raya, Enrique, Grau, Elena, Roman, Jose A, Vicente, Esther F, de Miguel, Eugenio, Lopez-Longo, Francisco J, Martinez, Lina, Morado, Inmaculada C et al. DOI: 10.1038/srep43953
PMID: 28263001 Journal: JOURNAL OF BONE AND MINERAL RESEARCH Year: 2017 Reference: J Bone Miner Res. 2017 Jul;32(7):1575-1581. doi: 10.1002/jbmr.3121. Epub 2017 May 11. Impact factor: 6.284 Publication type: Paper in international publication Authors: Herrera, Sabina, Perez-Lopez, Jordi, Molto-Abad, Marc, Guerri-Fernandez, Roberto, Cabezudo, Elena, Novelli, Silvana, Esteve, Jordi, Hernandez, Albert, Roig, Inmaculada, Solanich, Xavier et al. DOI: 10.1002/jbmr.3121
PMID: 24527046 Journal: EVID-BASED COMPL ALT Year: 2014 Reference: Evid Based Complement Alternat Med. 2014;2014:408436. doi: 10.1155/2014/408436. Epub 2014 Jan 9. Impact factor: 2.175 Publication type: Paper in international publication Authors: Sarzi Puttini, Piercarlo C, Alegre, Cayetano, Perrot, Serge, Langhorst, Jost, Hauser, Winfried, Lauche, Romy et al. DOI: 10.1155/2014/408436
PMID: 24469977 Journal: ARTHRIT CARE RES Year: 2014 Reference: Arthritis Care Res (Hoboken). 2014 Jun;66(6):968. doi: 10.1002/acr.22287. Impact factor: 4.039 Publication type: Letter whit IF Authors: Santos-Ortega, Alba, Arcos-Bertiz, Ibai Los, Martinez-Valle, Fernando et al. DOI: 10.1002/acr.22287
PMID: 24461380 Journal: J AUTOIMMUN Year: 2014 Reference: J Autoimmun. 2014 Feb-Mar;48-49:118-21. doi: 10.1016/j.jaut.2014.01.025. Epub 2014 Jan 22. Impact factor: 7.018 Publication type: Review in international publication Authors: Milisenda, J C, Selva-O'Callaghan, A, Grau, J M et al. DOI: 10.1016/j.jaut.2014.01.025
PMID: 24452223 Journal: INT J CARDIOL Year: 2014 Reference: Int J Cardiol. 2014 Mar 1;172(1):127-31. doi: 10.1016/j.ijcard.2013.12.169. Epub 2014 Jan 8. Impact factor: 6.175 Publication type: Paper in international publication Authors: Formiga, Francesc, Chivite, David, Conde, Alicia, Ruiz-Laiglesia, Fernando, Franco, Alvaro Gonzalez, Bocanegra, Carmen Perez, Manzano, Luis, Perez-Barquero, Manuel Montero et al. DOI: 10.1016/j.ijcard.2013.12.169
PMID: 21953614 Journal: ARTHRITIS AND RHEUMATISM Year: 2012 Reference: Arthritis Rheum. 2012 Feb;64(2):523-32. doi: 10.1002/art.33379. Impact factor: 7.866 Publication type: Paper in international publication Authors: , , , , , , , et al. DOI: 10.1002/art.33379
PMID: 21745025 Journal: Psychology Health & Medicine Year: 2012 Reference: Psychol Health Med. 2012 Mar;17(2):150-63. Epub 2011 Jul 11. Impact factor: 1.178 Publication type: Paper in international publication Authors: , , , , et al. DOI: 10.1080/13548506.2011.582124
PMID: 21905008 Journal: ARTHRITIS AND RHEUMATISM Year: 2012 Reference: Arthritis Rheum. 2012 Jan;64(1):264-71. doi: 10.1002/art.33325. Impact factor: 7.866 Publication type: Paper in international publication Authors: Camps, Mayte, Vonk, M C, Knaapen, H, Beretta, L, Rueda, B, Hesselstrand, R, Herrick, A, Worthington, J, Hunzelman, N, Denton, C P et al. DOI: 10.1002/art.33325
PMID: 21832821 Journal: RESPIRATION Year: 2012 Reference: Respiration. 2012;83(3):239-44. Epub 2011 Aug 11. Impact factor: 2.258 Publication type: Letter whit IF Authors: , , , , , , , et al. DOI: 10.1159/000329440
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
