About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 31983679 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2021 Reference: J Investig Allergol Clin Immunol. 2021 Jul 26;31(4):308-315. doi: 10.18176/jiaci.0483. Epub 2020 Jan 23. Impact factor: 7.033 Publication type: Paper in international publication Authors: Almonacid Sanchez, C, Melero Moreno, C, Quirce Gancedo, S, Sanchez-Herrero, M G, Alvarez Gutierrez, F J, Banas Conejero, D, Cardona, V, Soriano, J B et al. DOI: 10.18176/jiaci.0483
PMID: 34297774 Journal: PLoS One Year: 2021 Reference: PLoS One. 2021 Jul 23;16(7):e0255141. doi: 10.1371/journal.pone.0255141. eCollection 2021. Impact factor: 3.24 Publication type: Paper in international publication Authors: Garcia-Navarro, Jose Augusto, San-Jose, Antonio, Andreu, Antoni L, Campins, Magda, Almirante, Benito, Santaeugenia, Sebastia, Ussi, Anton, Lopez-Segui, Francesc, Meis-Pinheiro, Uxio, Walsh, Sandra et al. DOI: 10.1371/journal.pone.0255141
PMID: 34290006 Journal: BMJ case reports Year: 2021 Reference: BMJ Case Rep. 2021 Jul 21;14(7). pii: 14/7/e241766. doi: 10.1136/bcr-2021-241766. Impact factor: 0 Publication type: Letter or abstract Authors: Montoro, Bruno, Sanchez-Sancho, Pablo, Selva-O'Callaghan, Albert, Trallero-Araguas, Ernesto, Ros, Javier et al. DOI: 10.1136/bcr-2021-241766
PMID: 34262032 Journal: Nature Communications Year: 2021 Reference: Nat Commun. 2021 Jul 14;12(1):4319. doi: 10.1038/s41467-021-24618-3. Impact factor: 14.919 Publication type: Paper in international publication Authors: Andrades, Alvaro, Trastulli, Deborah, Pros, Eva, Setien, Fernando, Verdura, Sara, Farre, Lourdes, Martin-Tejera, Juan F, Llabata, Paula, Oaknin, Ana, Saigi, Maria et al. DOI: 10.1038/s41467-021-24618-3
PMID: 31963773 Journal: International Journal of Environmental Research and Public Health Year: 2020 Reference: Int J Environ Res Public Health. 2020 Jan 19;17(2). pii: ijerph17020634. doi: 10.3390/ijerph17020634. Impact factor: 2.849 Publication type: Paper in international publication Authors: Serrat, Mayte, Sanabria-Mazo, Juan P, Garcia-Troiteiro, Elna, Fontcuberta, Anna, Mateo-Canedo, Corel, Almirall, Miriam, Feliu-Soler, Albert, Mendez-Ulrich, Jorge Luis, Sanz, Antoni, Luciano, Juan V et al. DOI: 10.3390/ijerph17020634
PMID: 31838162 Journal: AUTOIMMUNITY REVIEWS Year: 2020 Reference: Autoimmun Rev. 2020 Feb;19(2):102455. doi: 10.1016/j.autrev.2019.102455. Epub 2019 Dec 12. Impact factor: 7.767 Publication type: Review in international publication Authors: Trallero-Araguas, Ernesto, Matas-Garcia, Ana, Milisenda, Jose C, Selva-O'Callaghan, Albert, Prieto-Gonzalez, Sergio, Padrosa, Joan, Cabrera, Carlos, Reguart, Noemi, Castrejon, Natalia, Sole, Manel et al. DOI: 10.1016/j.autrev.2019.102455
PMID: 31906988 Journal: Journal of Translational Medicine Year: 2020 Reference: J Transl Med. 2020 Jan 6;18(1):4. doi: 10.1186/s12967-019-02184-z. Impact factor: 4.124 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Escorihuela, Rosa Maria, Capdevila, Lluis, Castro, Juan Ramos, Zaragoza, Maria Cleofe, Maurel, Sara, Alegre, Jose et al. DOI: 10.1186/s12967-019-02184-z
PMID: 31113593 Journal: Annals of Hepatology Year: 2019 Reference: Ann Hepatol. 2019 Jan - Feb;18(1):215-219. doi: 10.5604/01.3001.0012.7916. Impact factor: 1.895 Publication type: Paper in international publication Authors: Martinez-Valle, Fernando, Riveiro-Barciela, Mar, Salcedo, Maria-Teresa, Merino-Casabiel, Xavier, Fernandez-Codina, Andreu, Torres, Ines de, Esteban, Rafael, Buti, Maria et al. DOI: 10.5604/01.3001.0012.7916
PMID: 30911161 Journal: NATURE GENETICS Year: 2019 Reference: Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038/s41588-019-0364-4. Epub 2019 Mar 25. Impact factor: 25.455 Publication type: Paper in international publication Authors: Mahajan, Milind C, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R, Purcell, Shaun, Demontis, Ditte, Borglum, Anders D, Walters, James T R, O'Donovan, Michael C, Sullivan, Patrick et al. DOI: 10.1038/s41588-019-0364-4
PMID: 31086353 Journal: NATURE GENETICS Year: 2019 Reference: Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038/s41588-019-0435-6. Impact factor: 25.455 Publication type: Letter or abstract Authors: Gamazon, Eric R, Huckins, Laura M, Dobbyn, Amanda, Ruderfer, Douglas M, Hoffman, Gabriel, Wang, Weiqing, Pardinas, Antonio F, Rajagopal, Veera M, Als, Thomas D, T Nguyen, Hoang et al. DOI: 10.1038/s41588-019-0435-6
PMID: 31081519 Journal: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING Year: 2019 Reference: Eur J Nucl Med Mol Imaging. 2019 Jul;46(8):1626-1632. doi: 10.1007/s00259-019-04339-y. Epub 2019 May 12. Impact factor: 7.182 Publication type: Paper in international publication Authors: Martinez-Valle, Fernando, Navales, Ignacio, Loureiro-Amigo, Jose, Solans-Laque, Roser, Simo-Perdigo, Marc, Mestre-Torres, Jaume et al. DOI: 10.1007/s00259-019-04339-y
PMID: 28248800 Journal: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY Year: 2017 Reference: J Clin Rheumatol. 2017 Apr;23(3):155-159. doi: 10.1097/RHU.0000000000000500. Impact factor: 1.322 Publication type: Paper in international publication Authors: Selva-O'Callaghan, Albert, Marin, Ana, Escola-Verge, Laura, Pinal-Fernandez, Iago, Fernandez-Codina, Andreu, Callejas-Moraga, Eduardo L, Espinosa, Juan, Labrador-Horrillo, Moises et al. DOI: 10.1097/RHU.0000000000000500
PMID: 28229826 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2017 Reference: Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):40-47. Epub 2017 Feb 6. Impact factor: 2.634 Publication type: Paper in international publication Authors: Rubio-Rivas, Manuel, Simeon-Aznar, Carmen Pilar, Velasco, Cesar, Mari-Alfonso, Begona, Espinosa, Gerard, Corbella, Xavier, Colunga-Arguelles, Dolores, Egurbide-Arberas, Maria Victoria, Ortego-Centeno, Norberto, Freire, Mayka et al. DOI:
PMID: 28225490 Journal: MEDICINE Year: 2017 Reference: Medicine (Baltimore). 2017 Feb;96(8):e6083. doi: 10.1097/MD.0000000000006083. Impact factor: 1.803 Publication type: Paper in international publication Authors: Solans-Laque, Roser, Fraile, Guadalupe, Rodriguez-Carballeira, Monica, Caminal, Luis, Castillo, Maria J, Martinez-Valle, Ferran, Saez, Luis, Rios, Juan J, Solanich, Xavier, Oristrell, Joaquim et al. DOI: 10.1097/MD.0000000000006083
PMID: 27043027 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2017 Reference: Rheumatol Int. 2017 Jan;37(1):177. doi: 10.1007/s00296-016-3470-y. Impact factor: 1.824 Publication type: Letter or abstract Authors: Fernandez-Codina, Andreu, Simeon-Aznar, Carmen Pilar, Pinal-Fernandez, Iago, Rodriguez-Palomares, Jose, Pizzi, Maria Nazarena, Hidalgo, Cristina Eve, Guillen-Del Castillo, Alfredo, Prado-Galbarro, Francisco Javier, Sarria-Santamera, Antonio, Fonollosa-Pla, Vicent et al. DOI: 10.1007/s00296-016-3470-y
PMID: 24438879 Journal: ARCH GERONTOL GERIAT Year: 2014 Reference: Arch Gerontol Geriatr. 2014 May-Jun;58(3):460-4. doi: 10.1016/j.archger.2013.12.006. Epub 2014 Jan 2. Impact factor: 1.525 Publication type: Paper in international publication Authors: San-Jose, Antonio, Agusti, Antonia, Vidal, Xavier, Barbe, Jose, Torres, Olga H, Ramirez-Duque, Nieves, Garcia, Juana, Fernandez-Moyano, Antonio, Lopez-Soto, Alfonso, Formiga, Francesc et al. DOI: 10.1016/j.archger.2013.12.006
PMID: 24356492 Journal: DERMATOLOGY Year: 2014 Reference: Dermatology. 2014;228(1):27-30. doi: 10.1159/000356779. Epub 2013 Dec 14. Impact factor: 1.685 Publication type: Paper in international publication Authors: Pinal-Fernandez, Iago, Solans-Laque, Roser et al. DOI: 10.1159/000356779
PMID: 24351900 Journal: J NEUROL SCI Year: 2014 Reference: J Neurol Sci. 2014 Feb 15;337(1-2):167-72. doi: 10.1016/j.jns.2013.12.003. Epub 2013 Dec 7. Impact factor: 2.262 Publication type: Paper in international publication Authors: Saez-Francas, Naia, Hernandez-Vara, Jorge, Corominas-Roso, Margarita, Alegre, Jose, Jacas, Carlos, Casas, Miguel et al. DOI: 10.1016/j.jns.2013.12.003
PMID: 24162151 Journal: RHEUMATOLOGY Year: 2014 Reference: Rheumatology (Oxford). 2014 Feb;53(2):321-31. doi: 10.1093/rheumatology/ket349. Epub 2013 Oct 25. Impact factor: 4.435 Publication type: Paper in international publication Authors: Ripoll, Mar, Pinilla, Blanca, Akasbi, Miriam, Fonseca, Eva, Canora, Jesus, Nadal, Maria-Elvira, Red, Gloria de la, Fernandez-Regal, Ines, Jimenez-Heredia, Iratxe, Bosch, Josep-Angel et al. DOI: 10.1093/rheumatology/ket349
PMID: 22133713 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2012 Reference: Arch Bronconeumol. 2012 Jan;48(1):8-13. Epub 2011 Nov 30. Impact factor: Publication type: Letter or abstract Authors: , , , , , , et al. DOI: 10.1016/j.arbres.2011.06.010
PMID: 22122552 Journal: DERMATOLOGIC SURGERY Year: 2012 Reference: Dermatol Surg. 2012 Jan;38(1):38-47. doi: 10.1111/j.1524-4725.2011.02221.x. Epub 2011 Nov 28. Impact factor: 1.798 Publication type: Paper in international publication Authors: , , , et al. DOI: 10.1111/j.1524-4725.2011.02221.x
PMID: 22294626 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2012 Reference: Ann Rheum Dis. 2012 Jun;71(6):993-6. doi: 10.1136/annrheumdis-2011-200871. Epub 2012 Jan 30. Impact factor: 8.727 Publication type: Paper in international publication Authors: , , , , , , et al. DOI: 10.1136/annrheumdis-2011-200871
PMID: 21992597 Journal: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY Year: 2012 Reference: Am J Reprod Immunol. 2012 Feb;67(2):140-151. doi: 10.1111/j.1600-0897.2011.01072.x. Epub 2011 Oct 13. Impact factor: 3.05 Publication type: Paper in international publication Authors: , , , , , et al. DOI: 10.1111/j.1600-0897.2011.01072.x
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
