About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 34269744 Journal: Current opinion in allergy and clinical immunology Year: 2021 Reference: Curr Opin Allergy Clin Immunol. 2021 Oct 1;21(5):435-441. doi: 10.1097/ACI.0000000000000771. Impact factor: 0 Publication type: Review in international publication Authors: Sala-Cunill, Anna, Cardona, Victoria et al. DOI: 10.1097/ACI.0000000000000771
PMID: 34221218 Journal: World Allergy Organization Journal Year: 2021 Reference: World Allergy Organ J. 2021 Jun 17;14(7):100557. doi: 10.1016/j.waojou.2021.100557. eCollection 2021 Jul. Impact factor: 4.084 Publication type: Letter or abstract Authors: Canonica, Giorgio Walter, Ansotegui, Ignacio J, Melioli, Giovanni, Monge Ortega, Olga Patricia, Morais-Almeida, Mario, Pfaar, Oliver, Poulsen, Lars K, Pawankar, Ruby, Renz, Harald E, Romano, Antonino G et al. DOI: 10.1016/j.waojou.2021.100557
PMID: 34201806 Journal: Antioxidants Year: 2021 Reference: Antioxidants (Basel). 2021 Jun 23;10(7). pii: antiox10071010. doi: 10.3390/antiox10071010. Impact factor: 6.313 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Zaragoza, Maria-Cleofe, Lopez-Vilchez, Irene, Galmes, Jose Luis, Maurel, Sara, Domingo, Joan Carles, Alegre-Martin, Jose, Cordobilla, Begona et al. DOI: 10.3390/antiox10071010
PMID: 34211589 Journal: Therapeutic Advances in Musculoskeletal Disease Year: 2021 Reference: Ther Adv Musculoskelet Dis. 2021 Jun 18;13:1759720X211020917. doi: 10.1177/1759720X211020917. eCollection 2021. Impact factor: 5.346 Publication type: Paper in international publication Authors: Bravo, Beatriz, Romero-Yuste, Susana, Salvatierra, Juan, Hidalgo, Cristina, Manrique, Sara, Romero-Gomez, Carlos, Moya, Patricia, Alvarez-Rivas, Noelia, Mendizabal, Javier, Ortiz-Sanjuan, Francisco et al. DOI: 10.1177/1759720X211020917
PMID: 31043678 Journal: PHARMACOGENOMICS JOURNAL Year: 2019 Reference: Pharmacogenomics J. 2019 Dec;19(6):547-555. doi: 10.1038/s41397-019-0090-4. Epub 2019 May 2. Impact factor: 3.503 Publication type: Paper in international publication Authors: Aterido, Adria, Palau, Nuria, Domenech, Eugeni, Nos Mateu, Pilar, Gutierrez, Ana, Gomollon, Fernando, Mendoza, Juan L, Garcia-Planella, Esther, Barreiro-de Acosta, Manuel, Munoz, Fernando et al. DOI: 10.1038/s41397-019-0090-4
PMID: 31036626 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2019 Reference: Ann Rheum Dis. 2019 Jul;78(7):967-973. doi: 10.1136/annrheumdis-2019-215024. Epub 2019 Apr 29. Impact factor: 14.299 Publication type: Paper in international publication Authors: Jousse-Joulin, Sandrine, D'Agostino, Maria Antonietta, Nicolas, Celine, Naredo, Esperanza, Ohrndorf, Sarah, Backhaus, Marina, Tamborrini, Giorgio, Chary-Valckenaere, Isabelle, Terslev, Lene, Bruyn, G A W et al. DOI: 10.1136/annrheumdis-2019-215024
PMID: 31004236 Journal: Metabolomics Year: 2019 Reference: Metabolomics. 2019 Apr 19;15(4):65. doi: 10.1007/s11306-019-1527-0. Impact factor: 3.167 Publication type: Paper in international publication Authors: Guma, Monica, Quehenberger, Oswald, Jain, Mohit, Coras, Roxana, Kavanaugh, Arthur, Boyd, Tristan, Huynh, Quyen, Pedersen, Brian, Armando, Aaron M, Dahlberg-Wright, Signe et al. DOI: 10.1007/s11306-019-1527-0
PMID: 30952369 Journal: GYNECOLOGIC ONCOLOGY Year: 2019 Reference: Gynecol Oncol. 2019 Jun;153(3):549-554. doi: 10.1016/j.ygyno.2019.03.241. Epub 2019 Apr 3. Impact factor: 4.393 Publication type: Paper in international publication Authors: Tejerizo, A, Lago, V, Fotopoulou, C, Chiantera, V, Minig, L, Gil-Moreno, A, Cascales-Campos, P A, Jurado, M, Di Donna, M C, Marina, T et al. DOI: 10.1016/j.ygyno.2019.03.241
PMID: 26497313 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2017 Reference: Rheumatol Int. 2017 Jan;37(1):75-84. doi: 10.1007/s00296-015-3382-2. Epub 2015 Oct 25. Impact factor: 1.824 Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu, Simeon-Aznar, Carmen Pilar, Pinal-Fernandez, Iago, Rodriguez-Palomares, Jose, Pizzi, Maria Nazarena, Hidalgo, Cristina Eve, Del Castillo, Alfredo Guillen, Prado-Galbarro, Francisco Javier, Sarria-Santamera, Antonio, Fonollosa-Pla, Vicent et al. DOI: 10.1007/s00296-015-3382-2
PMID: 27988433 Journal: AUTOIMMUNITY REVIEWS Year: 2017 Reference: Autoimmun Rev. 2017 Feb;16(2):168-172. doi: 10.1016/j.autrev.2016.12.008. Epub 2016 Dec 15. Impact factor: 8.961 Publication type: Review in international publication Authors: Martinez-Valle, Fernando, Fernandez-Codina, Andreu, Pinal-Fernandez, Iago, Orozco-Galvez, Olimpia, Vilardell-Tarres, Miquel et al. DOI: 10.1016/j.autrev.2016.12.008
PMID: 28086002 Journal: Arthritis & Rheumatology Year: 2017 Reference: Arthritis Rheumatol. 2017 May;69(5):1090-1099. doi: 10.1002/art.40045. Epub 2017 Apr 4. Impact factor: 6.918 Publication type: Paper in international publication Authors: Rothwell, Simon, Cooper, Robert G, Lundberg, Ingrid E, Gregersen, Peter K, Hanna, Michael G, Machado, Pedro M, Herbert, Megan K, Pruijn, Ger J M, Lilleker, James B, Roberts, Mark et al. DOI: 10.1002/art.40045
PMID: 28148759 Journal: JOURNAL OF RHEUMATOLOGY Year: 2017 Reference: J Rheumatol. 2017 Feb;44(2):260-261. doi: 10.3899/jrheum.160908. Impact factor: 3.15 Publication type: Letter whit IF Authors: Quesada-Masachs, Estefania, Caballero, Consuelo Modesto et al. DOI: 10.3899/jrheum.160908
PMID: 24022944 Journal: ARTHRIT CARE RES Year: 2014 Reference: Arthritis Care Res (Hoboken). 2014 Feb;66(2):334. doi: 10.1002/acr.22157. Impact factor: 4.039 Publication type: Letter whit IF Authors: Ortego-Centeno, Norberto, Simeon-Aznar, Carmen-Pilar, Callejas-Rubio, Jose-Luis, Rios-Fernandez, Raquel et al. DOI: 10.1002/acr.22157
PMID: 24354303 Journal: ANAL CHEM Year: 2014 Reference: Anal Chem. 2014 Jan 21;86(2):1160-9. doi: 10.1021/ac403110u. Epub 2013 Dec 31. Impact factor: 5.825 Publication type: Paper in international publication Authors: Alonso, Arnald, Rodriguez, Miguel A, Vinaixa, Maria, Tortosa, Raul, Correig, Xavier, Julia, Antonio, Marsal, Sara et al. DOI: 10.1021/ac403110u
PMID: 24387989 Journal: AM J HUM GENET Year: 2014 Reference: Am J Hum Genet. 2014 Jan 2;94(1):47-61. doi: 10.1016/j.ajhg.2013.12.002. Impact factor: 10.987 Publication type: Paper in international publication Authors: Lunardi, Claudio, Ochoa, Eguzkine, Carreira, Patricia, Simeon, Carmen Pilar, Castellvi, Ivan, Gonzalez-Gay, Miguel Angel, Zhernakova, Alexandra, Padyukov, Leonid, Alarcon-Riquelme, Marta, Wijmenga, Cisca et al. DOI: 10.1016/j.ajhg.2013.12.002
PMID: 24387955 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 Jun 16;142(12):519-25. doi: 10.1016/j.medcli.2013.06.030. Epub 2014 Jan 2. Impact factor: 1.252 Publication type: Paper in national publication Authors: Faro, Monica, Saez-Francas, Naia, Castro-Marrero, Jesus, Aliste, Luisa, Collado, Antonio, Alegre, Jose et al. DOI: 10.1016/j.medcli.2013.06.030
PMID: 22045834 Journal: JOURNAL OF RHEUMATOLOGY Year: 2012 Reference: J Rheumatol. 2012 Jan;39(1):112-118. Epub 2011 Nov 1. Impact factor: 3.695 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.3899/jrheum.110235
PMID: 22087014 Journal: RHEUMATOLOGY Year: 2012 Reference: Rheumatology (Oxford). 2012 Jan;51(1):52-9. Epub 2011 Nov 15. Impact factor: 4.058 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1093/rheumatology/ker335
PMID: 21641728 Journal: PSYCHONEUROENDOCRINOLOGY Year: 2012 Reference: Psychoneuroendocrinology. 2012 Jan;37(1):65-77. Epub 2011 Jun 8. Impact factor: 5.809 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1016/j.psyneuen.2011.05.005
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
