Diana Fernandes de Rafael

I possess a Master in Pharmaceutical Sciences (2010) granted by the Faculty of Pharmacy from the Lisbon University, and a PhD degree in Pharmaceutical Technology (2017) from the same University. During my PhD I had the opportunity to do research stays at Ludwig Maximillian University (LMU), Munich, Bellvitge Biomedical Research Institute (IDIBELL) and Vall D'Hebron Research Institute (VHIR), Barcelona. Actually, I am a post-doctoral researcher at Drug Delivery and Targeting Group, VHIR working in the field of nanotechnology-based drug delivery systems applied to several diseases.

Instituciones de las que forman parte

Investigador/a principal
Bioquímica Clínica, Vehiculización de Fármacos y Terapia

Vall Hebron Institut de Recerca

Diana Fernandes de Rafael

Instituciones de las que forman parte

Investigador/a principal
Bioquímica Clínica, Vehiculización de Fármacos y Terapia

Vall Hebron Institut de Recerca

Being a multidisciplinary scientist, during 10 years of research career I acquired expertise in different areas of knowledge such as Pharmaceutical Technology, Nanomedicine, Chemistry, Molecular Biology, Cancer Signalling Pathways, Preclinical Validation, etc. My board knowledge in the field of biomedical sciences granted by my training as pharmacist and my research experience, allowed me to have a comprehensive and integrative view of the different stages of drug development from the bench to the bedside. My career has been fully dedicated to the design, development, and preclinical validation of innovative delivery systems for a wide range of challenging diseases with a special attention to oncology.
My active participation at different international projects (12) and collaborations with a variety of research groups have resulted in the authorship of several publications in high impact peer-reviewed journals (35 publications, 15 as corresponding/first author, h-index 18). Also, she is co-inventor of two patents about delivery systems for gene delivery and the creation of cell penetrating peptides. Moreover, I am truly active in science dissemination both to share the knowhow with the pairs at international conferences, and also in citizenship dissemination actions. Additionally, due to her experience in the fields of Pharmaceutical Technology and Molecular Biology, I am giving classes at the Master of Molecular Biotechnology from the University of Barcelona. Most importantly, I was responsible for the supervision of the thesis of different pre-graduated, master and PhD students (14).

Proyectos

Hidrogeles Inteligentes y Biodegradables como Sistemas de Depósito para la Liberación Intraperitoneal Sostenida de Quimioterapéuticos para el Tratamiento Local del Cáncer de Ovario Avanzado (Smart-InOva)

IP: Diana Fernandes de Rafael
Colaboradores: Julia German Cortes, Fco Javier De la Torre Fdez de Vega, Simon Schwartz Navarro, Angels Alcina Mila, Sandra Mancilla Zamora, Belen Garcia Prats
Entidad financiadora: Instituto de Salud Carlos III
Financiación: 177500
Referencia: PI24/00745
Duración: 01/01/2025 - 31/12/2027

diVHulga. Programa anual de actividades UCC+I del Campus Vall d’Hebron (VH)

IP: Immaculada Hernández Rodríguez
Colaboradores: Josep Quer Sivila, Sara Ruiz Gallardo, Mayte Serrat Lopez, Julia Basallote Garciade Quiros, Beatriz Blasco Perez, Ariadna Laguna Tuset, Diana Fernandes de Rafael
Entidad financiadora: Fundación Española Ciencia y Tecnología (FECYT)
Financiación: 30000
Referencia: FCT-23-19812
Duración: 01/07/2024 - 30/06/2025

Evaluation of an innovative strategy based on nanoparticles-loaded hydrogels as a safe and sustained intraperitoneal chemotherapy in mucinous adenocarcinomas

IP: Fernanda Raquel Da Silva Andrade
Colaboradores: Roser Ferrer Costa, Julia German Cortes, Angels Alcina Mila, Diana Fernandes de Rafael
Entidad financiadora: Asociación Española Contra el Cáncer
Financiación: 10000
Referencia: SNRGS247164DASI
Duración: 01/06/2024 - 31/05/2026

Nanoclustered Affimers for Targeted KRAS Ablation in Pancreatic Ductal Adenocarcinoma

IP: Joaquin Seras Franzoso
Colaboradores: Diana Fernandes de Rafael
Entidad financiadora: Asociación Cáncer de Páncreas
Financiación: 50000
Referencia: ACANPAN/PROJECTES/2023/SERAS
Duración: 05/12/2023 - 04/12/2025