Matilde Lleonart Pajarin I am group leader of "Biomedical Research in Cancer Stem Cells" at VHIR. I arrived at VHIR 21 years ago after having worked in different prestigious international research centers: World Health Organization (WHO) at the International Agency for Research on Cancer (IARC) (Lyon, France), the Wolfson Institute for Biomedical Research (WIBR) in London and the Queen´s Mary University of London. Instituciones de las que forman parte Jefe de grupo Investigación biomédica con Células Madre de Cáncer Vall Hebron Institut de Recerca LinkedIn Twitter Orcid Matilde Lleonart Pajarin LinkedIn Twitter Orcid Instituciones de las que forman parte Jefe de grupo Investigación biomédica con Células Madre de Cáncer Vall Hebron Institut de Recerca I am group leader of "Biomedical Research in Cancer Stem Cells" at VHIR. I arrived at VHIR 21 years ago after having worked in different prestigious international research centers: World Health Organization (WHO) at the International Agency for Research on Cancer (IARC) (Lyon, France), the Wolfson Institute for Biomedical Research (WIBR) in London and the Queen´s Mary University of London.
My Research Group was recognized as an Emerging Research Group in 2009 by the Generalitat de Catalunya and later in 2014 as a Consolidated Research Group. Throughout my career I have been involved in cancer research from a more molecular point of view correlating key mutations in oncogenes and tumor suppressor genes with anatomical, pathological and clinical features of patients' tumors and also through cell culture studies to determine important key cell signaling pathways in tumorigenesis. Currently, the main lines of research of my Research Group focus on the identification and characterization of biological mechanisms in resistant cancer cells, including cancer stem cells, to unravel the pathways responsible for their resistance in breast, lung and head and neck cancer models. In addition, we are particularly focused on identifying molecular targets in resistant cancer cells and cancer stem cells affecting particularly aggressive tumors. The aim is to attack them pharmacologically in order to propose new cancer therapies: new drugs and/or drug combinations to combat resistant tumors in mouse models.
Proyectos Identificación y caracterización de nuevos genes que inmortalicen células primarias y su papel en tumores humanos IP: Matilde Lleonart Pajarin Colaboradores: Santiago Ramon y Cajal Agüeras, Carmela Iglesias i Felip, Javier Hernandez Losa Entidad financiadora: Instituto de Salud Carlos III Financiación: 94300 Referencia: PI040530 Duración: 01/01/2005 - 30/08/2008 Búsqueda de genes existentes en células embrionarias murinas que estén implicados en la inmortalización IP: Matilde Lleonart Pajarin Colaboradores: - Entidad financiadora: Instituto de Salud Carlos III Financiación: 42070 Referencia: CP03/00101 Duración: 01/03/2004 - 28/02/2007 Búsqueda de genes existentes en células embrionarias murinas que estén implicados en la inmortalización IP: Santiago Ramon y Cajal Agüeras Colaboradores: Matilde Lleonart Pajarin Entidad financiadora: Instituto de Salud Carlos III Financiación: Referencia: CP03/00101 Duración: 01/03/2004 - 28/02/2010 Paginación Primera página « Página anterior ‹ … Página 4 Página 5 Página 6 Página 7 Página actual 8
