About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 35229657 Journal: ANTIOXIDANTS & REDOX SIGNALING Year: 2022 Reference: Antioxid Redox Signal. 2022 Apr;36(10-12):729-739. doi: 10.1089/ars.2022.0018. Impact factor: 8.401 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Domingo, Joan Carles, Cordobilla, Begona, Ferrer, Roser, Giralt, Marina, Sanmartin-Sentanes, Ramon, Alegre-Martin, Jose et al. DOI: 10.1089/ars.2022.0018
PMID: 35234202 Journal: CLINICAL NUCLEAR MEDICINE Year: 2022 Reference: Clin Nucl Med. 2022 May 1;47(5):387-393. doi: 10.1097/RLU.0000000000004097. Impact factor: 7.794 Publication type: Paper in international publication Authors: Navales-Mateu, Ignacio, Mestre-Torres, Jaume, Martinez-Valle, Fernando, Gabaldon, Alejandra, Simo-Perdigo, Marc, Salcedo-Allende, M Teresa, Solans-Laque, Roser et al. DOI: 10.1097/RLU.0000000000004097
PMID: 35225224 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2022 Reference: Clin Exp Rheumatol. 2022 Feb;40(2):309-319. Epub 2022 Feb 25. Impact factor: 4.473 Publication type: Review in international publication Authors: Faghihi-Kashani, Sara, Scire, Carlo Alberto, Bonella, Francesco, Corte, Tamera J, Doyle, Tracy J, Fiorentino, David, Gonzalez-Gay, Miguel A, Hudson, Marie, Kuwana, Masataka, Lundberg, Ingrid E et al. DOI:
PMID: 34480833 Journal: Arthritis & Rheumatology Year: 2022 Reference: Arthritis Rheumatol. 2022 Mar;74(3):508-517. doi: 10.1002/art.41964. Epub 2022 Feb 1. Impact factor: 10.995 Publication type: Paper in international publication Authors: Pinal-Fernandez, Iago, Pak, Katherine, Huang, Wilson, Selva-O'Callaghan, Albert, Albayda, Jemima, Casciola-Rosen, Livia, Paik, Julie J, Tiniakou, Eleni, Mecoli, Christopher A, Lloyd, Thomas E et al. DOI: 10.1002/art.41964
PMID: 34603940 Journal: Current treatment options in rheumatology Year: 2021 Reference: Curr Treatm Opt Rheumatol. 2021;7(4):319-333. doi: 10.1007/s40674-021-00186-x. Epub 2021 Sep 28. Impact factor: 0 Publication type: Review in international publication Authors: Sanchez-Pernaute, O, Pinal-Fernandez, I, Ruiz-Rodriguez, J C, Gil-Vila, A, Trallero-Araguas, E, Romero-Bueno, F, Selva-O'Callaghan, A et al. DOI: 10.1007/s40674-021-00186-x
PMID: 34596027 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2021 Reference: Clin Exp Rheumatol. 2021 Sep 21. pii: 17302. Impact factor: 4.473 Publication type: Paper in international publication Authors: Rodriguez-Muguruza, Samantha, Combe, Bernard, Guillemin, Francis, Fautrel, Bruno, Olive, Alejandro, Marsal, Sara, Valero, Oliver, Lukas, Cedric et al. DOI:
PMID: 34575280 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Sep 15;10(18). pii: jcm10184171. doi: 10.3390/jcm10184171. Impact factor: 4.242 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Zacares, Mario, Almenar-Perez, Eloy, Alegre-Martin, Jose, Oltra, Elisa et al. DOI: 10.3390/jcm10184171
PMID: 34582103 Journal: Clinical and Translational Allergy Year: 2021 Reference: Clin Transl Allergy. 2021 Aug;11(7):e12052. doi: 10.1002/clt2.12052. Impact factor: 5.871 Publication type: Review in international publication Authors: Pascal, Mariona, Moreno, Carmen, Davila, Ignacio, Tabar, Ana I, Labrador, Moises, Luengo, Olga, Bartra, Joan et al. DOI: 10.1002/clt2.12052
PMID: 31530514 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2020 Reference: J Investig Allergol Clin Immunol. 2020;30(1):67. doi: 10.18176/jiaci.0444. Epub 2019 Sep 18. Impact factor: 3.488 Publication type: Paper in international publication Authors: Castillo Marchuet, M J, Luengo, O, Cardona, V et al. DOI: 10.18176/jiaci.0444
PMID: 31365334 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2020 Reference: Clin Exp Rheumatol. 2020 Jan-Feb;38(1):67-73. Epub 2019 Jul 30. Impact factor: 3.319 Publication type: Paper in international publication Authors: Dani, Lara, Holmqvist, Marie, Martinez, Maria Angeles, Trallero-Araguas, Ernesto, Dastmalchi, Maryam, Svensson, John, Labrador-Horrillo, Moises, Selva-O'Callaghan, Albert, Lundberg, Ingrid E et al. DOI:
PMID: 31203229 Journal: JOURNAL OF RHEUMATOLOGY Year: 2020 Reference: J Rheumatol. 2020 Mar;47(3):407-414. doi: 10.3899/jrheum.190065. Epub 2019 Jun 15. Impact factor: 3.35 Publication type: Paper in international publication Authors: Garcia-Vives, Eloi, Segarra-Medrano, Alfons, Martinez-Valle, Ferran, Agraz, Irene, Solans-Laque, Roser et al. DOI: 10.3899/jrheum.190065
PMID: 31230373 Journal: ALLERGY Year: 2020 Reference: Allergy. 2020 Feb;75(2):259-272. doi: 10.1111/all.13953. Epub 2019 Sep 16. Impact factor: 8.706 Publication type: Paper in international publication Authors: Blaiss, Michael S, Matricardi, Paolo Maria, Dramburg, Stephanie, Alvarez-Perea, Alberto, Antolin-Amerigo, Dario, Apfelbacher, Christian, Atanaskovic-Markovic, Marina, Berger, Uwe, Pfaar, Oliver, Pitsios, Constantinos et al. DOI: 10.1111/all.13953
PMID: 31261500 Journal: MEDICINE Year: 2019 Reference: Medicine (Baltimore). 2019 Jun;98(26):e15947. doi: 10.1097/MD.0000000000015947. Impact factor: 1.87 Publication type: Paper in international publication Authors: Corominas, Hector, Alegre, Cayetano, Narvaez, Javier, Fernandez-Cid, Carlos Marras, Torrente-Segarra, Vicenc, Gomez, Manuel Rodriguez, Pan, Francisco Maceiras, Morla, Rosa Maria, Martinez, Fernando Jose Rodriguez, Gomez-Centeno, Antoni et al. DOI: 10.1097/MD.0000000000015947
PMID: 31253111 Journal: BMC PUBLIC HEALTH Year: 2019 Reference: BMC Public Health. 2019 Jun 28;19(1):840. doi: 10.1186/s12889-019-7225-z. Impact factor: 2.567 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Faro, Monica, Zaragoza, Maria Cleofe, Aliste, Luisa, de Sevilla, Tomas Fernandez, Alegre, Jose et al. DOI: 10.1186/s12889-019-7225-z
PMID: 31253480 Journal: MEDICINA CLINICA Year: 2019 Reference: Med Clin (Barc). 2019 Dec 13;153(11):437-440. doi: 10.1016/j.medcli.2019.04.022. Epub 2019 Jun 26. Impact factor: 1.277 Publication type: Paper in national publication Authors: Milisenda, Jose C, Garcia, Ana Matas, Jou, Cristina, Pinal-Fernandez, Iago, O'Callaghan, Albert Selva, Grau, Josep Maria et al. DOI: 10.1016/j.medcli.2019.04.022
PMID: 31237427 Journal: Arthritis & Rheumatology Year: 2019 Reference: Arthritis Rheumatol. 2019 Dec;71(12):2081-2089. doi: 10.1002/art.41026. Epub 2019 Oct 21. Impact factor: 9.002 Publication type: Paper in international publication Authors: Ruiz-Moreno, Oscar, Atienza-Mateo, Belen, Martin-Varillas, Jose Luis, Calvo-Rio, Vanesa, Fernandez-Cid, Carlos, Aurrecoechea, Elena, Garcia-Arias, Miriam, Castaneda, Santos, Caracuel-Ruiz, Miguel A, Montilla-Morales, Carlos A et al. DOI: 10.1002/art.41026
PMID: 28905404 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Feb;73(2):323-327. doi: 10.1111/all.13306. Epub 2017 Oct 11. Impact factor: 6.048 Publication type: Paper in international publication Authors: Hoffmann, Hans Jurgen, Pfaar, Oliver, Cardona, Victoria, Demoly, Pascal, Dreborg, Sten, Fusun Kalpaklioglu, A, Klimek, Ludger, Muraro, Antonella, Popov, Todor A et al. DOI: 10.1111/all.13306
PMID: 29331045 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Sep;73(9):1792-1800. doi: 10.1111/all.13408. Epub 2018 Jun 17. Impact factor: 6.048 Publication type: Paper in international publication Authors: DunnGalvin, Audrey, Eigenmann, Philippe A, Halken, Susanne, Hoffmann-Sommergruber, Karin, Lau, Susanne, Nilsson, Caroline, Poulsen, Lars K, Rueff, Franziska, Spergel, Jonathan, Sturm, Gunter et al. DOI: 10.1111/all.13408
PMID: 29318637 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jun;73(6):1322-1330. doi: 10.1111/all.13380. Epub 2018 Mar 8. Impact factor: 6.048 Publication type: Paper in international publication Authors: Worm, Margitta, Francuzik, Wojciech, Renaudin, Jean-Marie, Bilo, Maria Beatrice, Cardona, Victoria, Hofmeier, Kathrin Scherer, Kohli, Alice, Bauer, Andrea, Christoff, George, Cichocka-Jarosz, Ewa et al. DOI: 10.1111/all.13380
PMID: 29171712 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jan;73 Suppl 104:5-23. doi: 10.1111/all.13355. Impact factor: 6.048 Publication type: Review in international publication Authors: Pfaar, O, Bonini, S, Cardona, V, Demoly, P, Jakob, T, Jutel, M, Kleine-Tebbe, J, Klimek, L, Klysner, S, Kopp, M V et al. DOI: 10.1111/all.13355
PMID: 28450313 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2017 Reference: Ann Rheum Dis. 2017 Sep;76(9):1575-1582. doi: 10.1136/annrheumdis-2016-210882. Epub 2017 Apr 27. Impact factor: 12.811 Publication type: Paper in international publication Authors: Ordi-Ros, Josep, Saez-Comet, Luis, Perez-Conesa, Mercedes, Vidal, Xavier, Mitjavila, Francesca, Castro Salomo, Antoni, Cuquet Pedragosa, Jordi, Ortiz-Santamaria, Vera, Mauri Plana, Montserrat, Cortes-Hernandez, Josefina et al. DOI: 10.1136/annrheumdis-2016-210882
PMID: 28432600 Journal: DRUGS & AGING Year: 2017 Reference: Drugs Aging. 2017 Jun;34(6):453-466. doi: 10.1007/s40266-017-0452-z. Impact factor: 2.769 Publication type: Paper in international publication Authors: Marquez, Paola H Ponte, Torres, Olga H, San-Jose, Anonio, Vidal, Xavier, Agusti, Antonia, Formiga, Francesc, Lopez-Soto, Alfonso, Ramirez-Duque, Nieves, Fernandez-Moyano, Antonio, Garcia-Moreno, Juana et al. DOI: 10.1007/s40266-017-0452-z
PMID: 28426925 Journal: Arthritis & Rheumatology Year: 2017 Reference: Arthritis Rheumatol. 2017 Sep;69(9):1914-1915. doi: 10.1002/art.40129. Epub 2017 Jul 11. Impact factor: 6.918 Publication type: Letter or abstract Authors: Bernal-Bello, David, Guillen-Del Castillo, Alfredo, Selva-O'Callaghan, Albert, Garcia de Tena, Jaime, Fonollosa-Pla, Vicent, Simeon-Aznar, Carmen Pilar et al. DOI: 10.1002/art.40129
PMID: 28410878 Journal: MOLECULAR GENETICS AND METABOLISM Year: 2017 Reference: Mol Genet Metab. 2017 Jun;121(2):138-149. doi: 10.1016/j.ymgme.2017.04.004. Epub 2017 Apr 9. Impact factor: 3.769 Publication type: Paper in international publication Authors: Perez-Lopez, Jordi, Morales-Conejo, Montserrat, Lopez-Rodriguez, Monica, Hermida-Ameijeiras, Alvaro, Molto-Abad, Marc et al. DOI: 10.1016/j.ymgme.2017.04.004
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The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
