About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 35188463 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2022 Reference: J Investig Allergol Clin Immunol. 2022 Feb;32(1):1-12. doi: 10.18176/jiaci.0769. Impact factor: 7.033 Publication type: Review in international publication Authors: Luengo, O, Labrador-Horrillo, M et al. DOI: 10.18176/jiaci.0769
PMID: 33146762 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2022 Reference: Rheumatol Int. 2022 Mar;42(3):441-448. doi: 10.1007/s00296-020-04733-y. Epub 2020 Nov 4. Impact factor: 2.631 Publication type: Paper in international publication Authors: Reina Sanz, Delia, Moya Alvarado, Patricia, de Agustin de Oro, Juan Jose, Aparicio Espinar, Maria, Armengol Perez, Eulalia, Busquets Perez, Noemi, Carmona, Loreto, Casado Burgos, Enrique, Clavaguera Poch, Teresa, Cuervo Aguilera, Andrea et al. DOI: 10.1007/s00296-020-04733-y
PMID: 35174793 Journal: Current Opinion in Allergy and Clinical Immunology Year: 2022 Reference: Curr Opin Allergy Clin Immunol. 2022 Jun 1;22(3):175-180. doi: 10.1097/ACI.0000000000000822. Epub 2022 Feb 16. Impact factor: 3.142 Publication type: Paper in international publication Authors: Luengo, Olga, Galvan-Blasco, Paula, Cardona, Victoria et al. DOI: 10.1097/ACI.0000000000000822
PMID: 34343358 Journal: ALLERGY Year: 2022 Reference: Allergy. 2022 Feb;77(2):357-377. doi: 10.1111/all.15032. Epub 2021 Sep 1. Impact factor: 13.146 Publication type: Paper in international publication Authors: Oude Elberink, Hanneke N G, Regent, Lynne, Sanchez, Angel, Vlieg-Boerstra, Berber J, Roberts, Graham, Michaelis, Louise J, Khaleva, Ekaterina, Jensen, Britt, Halken, Susanne, Muraro, Antonella et al. DOI: 10.1111/all.15032
PMID: 34567526 Journal: Clinical and Translational Allergy Year: 2021 Reference: Clin Transl Allergy. 2021 Sep 19;11(7):e12062. doi: 10.1002/clt2.12062. eCollection 2021 Aug. Impact factor: 5.871 Publication type: Review in international publication Authors: Brussino, Luisa, Cardona, Victoria, Cruz, Alvaro A, de Vries, Govert, Devillier, Philippe, Fokkens, Wytske J, Fuentes-Perez, Jose Miguel, Gemicioglu, Bilun, Haahtela, Tari, Huerta-Villalobos, Yunen Rocio et al. DOI: 10.1002/clt2.12062
PMID: 34444817 Journal: Nutrients Year: 2021 Reference: Nutrients. 2021 Jul 30;13(8). pii: nu13082658. doi: 10.3390/nu13082658. Impact factor: 5.719 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Segundo, Maria Jose, Lacasa, Marcos, Martinez-Martinez, Alba, Sentanes, Ramon Sanmartin, Alegre-Martin, Jose et al. DOI: 10.3390/nu13082658
PMID: 34397526 Journal: EUROPEAN JOURNAL OF ANAESTHESIOLOGY Year: 2021 Reference: Eur J Anaesthesiol. 2021 Sep 1;38(9):916-922. doi: 10.1097/EJA.0000000000001484. Impact factor: 4.33 Publication type: Paper in international publication Authors: Pardos-Gea, Josep, Alijotas-Reig, Jaume, Esteve-Valverde, Enrique, Ferrer-Oliveras, Raquel, Saez-Comet, Luis, Lefkou, Elmina, Mekinian, Arsene, Belizna, Cristina, Ruffatti, Amelia, Tincani, Angela et al. DOI: 10.1097/EJA.0000000000001484
PMID: 34386153 Journal: World Allergy Organization Journal Year: 2021 Reference: World Allergy Organ J. 2021 Jul 28;14(8):100569. doi: 10.1016/j.waojou.2021.100569. eCollection 2021 Aug. Impact factor: 4.084 Publication type: Review in international publication Authors: Ansotegui, Ignacio J, Gonzalez-Diaz, Sandra Nora, Bilo, Maria Beatrice, Cardona, Victoria, Park, Hae-Sim, Braschi, Maria Chiara, Macias-Weinmann, Alejandra, Piga, Mario A, Acuna-Ortega, Natalhie, Sanchez-Borges, Mario et al. DOI: 10.1016/j.waojou.2021.100569
PMID: 32101173 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2020 Reference: J Investig Allergol Clin Immunol. 2020;30(4):296-298. doi: 10.18176/jiaci.0498. Epub 2020 Feb 25. Impact factor: 3.488 Publication type: Paper in international publication Authors: Navas, A, Serrano, P, Espinazo, M, Labrador-Horrillo, M, Monsalve, R I, Jurado, A, Moreno-Aguilar, C, Ruiz-Leon, B et al. DOI: 10.18176/jiaci.0498
PMID: 32085620 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2020 Reference: Int J Mol Sci. 2020 Feb 18;21(4). pii: ijms21041372. doi: 10.3390/ijms21041372. Impact factor: 4.556 Publication type: Paper in international publication Authors: Garcia-Vives, Eloi, Sole, Cristina, Moline, Teresa, Vidal, Marta, Agraz, Irene, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al. DOI: 10.3390/ijms21041372
PMID: 31945019 Journal: JCI Insight Year: 2020 Reference: JCI Insight. 2020 Feb 13;5(3). pii: 134189. doi: 10.1172/jci.insight.134189. Impact factor: 6.205 Publication type: Paper in international publication Authors: Seto, Nickie, Torres-Ruiz, Jose Jiram, Carmona-Rivera, Carmelo, Pinal-Fernandez, Iago, Pak, Katherine, Purmalek, Monica M, Hosono, Yuji, Fernandes-Cerqueira, Catia, Gowda, Prateek, Arnett, Nathan et al. DOI: 10.1172/jci.insight.134189
PMID: 32024964 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Feb 5;10(1):1862. doi: 10.1038/s41598-020-58741-w. Impact factor: 3.998 Publication type: Paper in international publication Authors: Simeon, Carmen P, Fonollosa, Vicente, Guillen, Alfredo, Carreira, Patricia, Castellvi, Ivan, Gonzalez-Gay, Miguel A, Rios, Raquel, Callejas-Rubio, Jose Luis, Vargas-Hitos, Jose A, Garcia-Portales, Rosa et al. DOI: 10.1038/s41598-020-58741-w
PMID: 31229481 Journal: ANNALS OF THORACIC SURGERY Year: 2019 Reference: Ann Thorac Surg. 2019 Oct;108(4):1052-1058. doi: 10.1016/j.athoracsur.2019.04.096. Epub 2019 Jun 21. Impact factor: 3.919 Publication type: Paper in international publication Authors: Loor, Karina, Culebras, Mario, Sansano, Irene, Alvarez, Antonio, Berastegui, Cristina, de Gracia, Javier et al. DOI: 10.1016/j.athoracsur.2019.04.096
PMID: 31229269 Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Year: 2019 Reference: J Allergy Clin Immunol. 2019 Sep;144(3):627-633. doi: 10.1016/j.jaci.2019.05.013. Epub 2019 Jun 20. Impact factor: 14.11 Publication type: Review in international publication Authors: Sanchez-Borges, Mario, Rosenwasser, Lanny J, Ansontegui, Ignacio, Ebisawa, Motohiro, Sisul, Juan Carlos, Jares, Edgardo, Gomez, Maximiliano, Agache, Ioana, Hellings, Peter, Muraro, Antonella et al. DOI: 10.1016/j.jaci.2019.05.013
PMID: 31178295 Journal: MEDICINA CLINICA Year: 2019 Reference: Med Clin (Barc). 2019 Aug 16;153(4):169-177. doi: 10.1016/j.medcli.2019.01.030. Epub 2019 Jun 6. Impact factor: 1.277 Publication type: Paper in national publication Authors: Siso-Almirall, Antonio, Solans, Rosa, Fernandez-Real, Jose Manuel, Carrion, Jose Antonio, Graupera, Isabel, Gines, Pere, Vila, Lluis, Goday, Antonio, Hernandez, Maria Rosa, Caballeria, Llorenc et al. DOI: 10.1016/j.medcli.2019.01.030
PMID: 31169597 Journal: Current Opinion in Allergy and Clinical Immunology Year: 2019 Reference: Curr Opin Allergy Clin Immunol. 2019 Oct;19(5):439-446. doi: 10.1097/ACI.0000000000000550. Impact factor: 3.014 Publication type: Paper in international publication Authors: Sala-Cunill, Anna, Luengo, Olga, Cardona, Victoria et al. DOI: 10.1097/ACI.0000000000000550
PMID: 29314762 Journal: International Journal of Rheumatic Diseases Year: 2018 Reference: Int J Rheum Dis. 2018 Feb;21(2):487-496. doi: 10.1111/1756-185X.13255. Epub 2018 Jan 5. Impact factor: 2.423 Publication type: Paper in international publication Authors: Redondo-Benito, Ada, Curran, Adrian, Villar-Gomez, Ana, Trallero-Araguas, Ernesto, Fernandez-Codina, Andreu, Pinal-Fernandez, Iago, Rodrigo-Pendas, Jose Angel, Selva-O'Callaghan, Albert et al. DOI: 10.1111/1756-185X.13255
PMID: 28600902 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jan;73(1):77-92. doi: 10.1111/all.13218. Epub 2017 Aug 24. Impact factor: 6.048 Publication type: Paper in international publication Authors: De Feo, G, Bousquet, J, Agache, I, Aliberti, M R, Angles, R, Annesi-Maesano, I, Anto, J M, Arnavielhe, S, Asayag, E, Bacci, E et al. DOI: 10.1111/all.13218
PMID: 28249725 Journal: JOINT BONE SPINE Year: 2018 Reference: Joint Bone Spine. 2018 Jan;85(1):119. doi: 10.1016/j.jbspin.2017.02.008. Epub 2017 Feb 27. Impact factor: 3.304 Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu, Simo, Marc, Solans-Laque, Roser, Martinez-Valle, Fernando et al. DOI: 10.1016/j.jbspin.2017.02.008
PMID: 28396659 Journal: Frontiers in Immunology Year: 2017 Reference: Front Immunol. 2017 Mar 27;8:299. doi: 10.3389/fimmu.2017.00299. eCollection 2017. Impact factor: 6.429 Publication type: Paper in international publication Authors: Tome, Adria, Yague, Jordi, Anton, Jordi, Hernandez-Rodriguez, Jose, Castellanos-Moreira, Raul, Espanol-Rego, Marta, Soriano, Alessandra, Ruiz-Ortiz, Estibaliz, Iglesias, Estibaliz, Bujan-Rivas, Segundo et al. DOI: 10.3389/fimmu.2017.00299
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The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
