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DocTIS: Decision on optimal combinatorial therapies in Immune-Medicated Inflammatory Diseases (IMIDs) using systems approaches

  • Protocol code: SPON 2002-24
  • EudraCT code: _
  • Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més
  • Principal investigator:  Lopez Lasanta, Maria America
  • Research group:  Reumatologia
  • Service: Reumatologia
  • Phase: Fase II
  • Recruiting: Open
  • Status: Iniciat

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
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Estudio fase 3, aleatorizado, doble ciego, controlado con placebo, para evaluar la eficacia y la seguridad de KarXT para el tratamiento de episodios maníacos en el trastorno bipolar I (BALSAM-2)

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Estudio en fase II/III para evaluar la eficacia y la seguridad deltratamiento con KPL-387 en participantes con pericarditis recurrente

  • Protocol code: KPL-387-C211
  • EudraCT code: No aplica
  • Pathology: Malalties del sistema circulatori
  • Principal investigator:  Rello Sabaté, Pau
  • Research group:  Malalties cardiovasculars
  • Service: Cardiologia
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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Ensayo de fase III, multicéntrico, aleatorizado y en abierto de trastuzumab deruxtecán (Enhertu®) más quimioterapia con o sin pembrolizumab en comparación con quimioterapia más trastuzumab con o sin pembrolizumab como tratamiento de primera línea en participantes con cáncer gástrico o de la unión gastroesofágica (UGE) positivo para HER2 irresecable, localmente avanzado o metastásico (DESTINY-GASTRIC05)

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TRITON-CM: Estudio global de fase 3 , aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia y la seguridad de nucresirán en pacientes con amiloidosis por transtiretina con miocardiopatía (amiloidosis ATTR con miocardiopatía)

  • Protocol code: ALN-TTRSC04-003
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Martínez Valle, Fernando
  • Research group:  Malalties sistèmiques
  • Service: Medicina Interna
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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A Phase 1 Placebo-Controlled Dose-Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ARO-ATXN2 in Adult Subjects with Spinocerebellar Ataxia Type 2

  • Protocol code: AROATXN2-1001
  • EudraCT code: No aplica
  • Pathology: Malalties del sistema nerviós
  • Principal investigator:  Hernández Vara, Jorge
  • Research group:  Malalties neurodegeneratives
  • Service: Neurologia
  • Phase: Fase I
  • Recruiting: Closed
  • Status: Open

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A Phase 3 Randomized, Open Label Study to Evaluate the Efficacy andSafety of Tobevibart+Elebsiran Combination Therapy in Participants with Chronic HDVInfection Not Virologically Suppressed with Bulevirtide

  • Protocol code: VIR-CHDV-V205
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Buti Ferret, Maria
  • Research group:  Malalties hepàtiques
  • Service: Hepatologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio abierto para investigar la seguridad y eficacia a largo plazo de belimumabadministrado por vía subcutánea en adultos con enfermedad pulmonar intersticialasociada a esclerosis sistémica (SSc-ILD).

  • Protocol code: 219855
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Guillen Del Castillo, Alfredo
  • Research group:  Systemic Diseases
  • Service: Internal Medicine
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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A randomized, double-blind, placebo-controlled, parallel group Phase 2a study with an extension phase to evaluate the efficacy and safety of BAY 3401016 in participants aged 18 to 45 with Alport syndrome.

  • Protocol code: 22419
  • EudraCT code: _
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Sans Atxer, Laia
  • Research group:  Nefrologia i trasplantament renal
  • Service: Nefrologia
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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Randomised, multicentre, double-blind clinical trial to evaluate the efficacy and safety of Montelukast vs. placebo in patients with erosive/inflammatory osteoarthritis of the hands”. MOTHER STUDY

  • Protocol code: FMLD-ARSIDOS-65_FIII
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  De Agustin De Oro, Juan Jose
  • Research group:  Rheumatology
  • Service: Rheumatology
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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Estudio de fase 2, multicéntrico, aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia y seguridad de ALXN2030 en pacientes adultos con rechazo mediado por anticuerpos después de un trasplante de riñón.

  • Protocol code: ALXN2030-AMR-201
  • EudraCT code: _
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Moreso Mateos, Francesc
  • Research group:  Nephrology and kidney transplantation
  • Service: Nephrology
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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Ensayo de fase III, doble ciego, aleatorizado y controlado con placebo para evaluar los resultados clínicos relacionados con el hígado y la seguridad de la suvodutida administrada en inyección una vez a la semana en participantes con cirrosis por esteatohepatitis no alcoholica/esteatohepatitis asociada a disfunción metabólica (EHNA/EHADM) compensada

  • Protocol code: 1404-0044
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Pericàs Pulido, Juan Manuel
  • Research group:  Liver Diseases
  • Service: Hepatology
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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Estudio de fase II para evaluar la seguridad y la eficacia deAtacicept en múltiples enfermedades autoinmunitarias glomerulares (PIONEER)

  • Protocol code: VT-001-0060
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Agraz Pamplona, Irene
  • Research group:  Nephrology and kidney transplantation
  • Service: Nephrology
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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Estudio fase III, abierto, de extensión, para evaluar la seguridad a largo plazo de KarXT para el tratamiento de la manía o la manía con características mixtas en el trastorno bipolar I (BALSAM-3)

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ESTUDIO DE FASE III, MULTICÉNTRICO, ALEATORIZADO,CON DOBLE ENMASCARAMIENTO Y COMPARATIVO CON PLACEBO PARAEVALUAR LA EFICACIA Y LA SEGURIDAD DE PRASINEZUMAB INTRAVENOSOEN PARTICIPANTES CON ENFERMEDAD DE PARKINSON INCIPIENTE.

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ESTUDIO EN FASE II, MULTICÉNTRICO, ALEATORIZADO, ABIERTO Y DE GRUPOS PARALELOS PARA EVALUAR LA BIOEQUIVALENCIA DE DOS FORMULACIONES SUBCUTÁNEAS DE OCRELIZUMAB EN PACIENTES CON ESCLEROSIS MÚLTIPLE

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“Estudio de fase III, aleatorizado, doble ciego y controlado con placebo de Pasritamig (JNJ-78278343), un fármaco que redirige los linfocitos T y actúa sobre la calicreína humana 2, en combinación con el mejor tratamiento de soporte frente al mejor tratamiento de soporte para el cáncer de próstata metastásico resistente a la castración”

  • Protocol code: 78278343PCR3001
  • EudraCT code: No aplica
  • Pathology: Tumors
  • Principal investigator:  Valderrama Rodríguez, Angelica
  • Service: Sense classificar
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Protocolo maestro para un estudio de plataforma de fase II, abierto, con varios fármacos, multicéntrico, para evaluar la seguridad, tolerabilidad, farmacocinética y actividad antitumoral preliminar de fármacos novedosos o combinaciones como tratamiento perioperatorio en participantes con adenocarcinoma gastroesofágico resecable localmente avanzado (GEMINI-PeriOp GC)

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Phase 3 Randomized, Double-blind, Placebo controlled Study to Evaluatethe Efficacy and Safety of Maridebart Cafraglutide on Mortality and Morbidity inParticipants Living With Heart Failure With Preserved or Mildly Reduced Ejection Fractionand Obesity (MARITIME-HF)]

  • Protocol code: 20230227
  • EudraCT code: No aplica
  • Pathology: Circulatory system diseases
  • Principal investigator:  Soriano Colomé, Toni
  • Research group:  Cardiovascular Diseases
  • Service: Cardiology
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

A Phase 1/1b Study of ASP2138 as Monotherapy and in Combination with Pembrolizumab and mFOLFOX6 or Ramucirumab and Paclitaxel in Participants with Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma and in Combination with mFOLFIRINOX in Participants with Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma Whose Tumors Have Claudin (CLDN) 18.2 Expression

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.