About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37695530 Journal: JOURNAL OF NEUROLOGY Year: 2023 Reference: J Neurol. 2023 Sep 11. doi: 10.1007/s00415-023-11973-y. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Buti, Maria; Castillo, Joaquin; Marzo, Blanca; Montalban, Xavier; Otero-Romero, Susana; Otero-Romero, Susana; Riveiro-Barciela, Mar; Riveiro-Barciela, Mar; Robles-Sanchez, Miguel-Angel et al. DOI: 10.1007/s00415-023-11973-y
PMID: 37691049 Journal: Expert Review of Anti-Infective Therapy Year: 2023 Reference: Expert Rev Anti Infect Ther. 2023 Sep 10. doi: 10.1080/14787210.2023.2257392. Impact factor: Publication type: Review in international publication Authors: Cilloniz, Catia; Curioso, Walter H; Pericas, Juan Manuel; Pericas, Juan Manuel et al. DOI: 10.1080/14787210.2023.2257392
PMID: 37326326 Journal: HEPATOLOGY Year: 2023 Reference: Hepatology. 2023 Jun 21. doi: 10.1097/HEP.0000000000000431. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Buti, Maria; Ghany, Marc G; Lampertico, Pietro; Lee, Hannah M et al. DOI: 10.1097/HEP.0000000000000431
PMID: 37377088 Journal: JOURNAL OF HEPATOLOGY Year: 2023 Reference: J Hepatol. 2023 Jun 21:S0168-8278(23)00417-8. doi: 10.1016/j.jhep.2023.06.002. Impact factor: Publication type: Review in international publication Authors: Buti, Maria; Buti, Maria; Ghany, Marc G; Lampertico, Pietro; Lee, Hannah M et al. DOI: 10.1016/j.jhep.2023.06.002
PMID: 35643936 Journal: LIVER INTERNATIONAL Year: 2022 Reference: Liver Int. 2022 Aug;42(8):1783-1792. doi: 10.1111/liv.15323. Epub 2022 Jun 7. Impact factor: Publication type: Paper in international publication Authors: Abad, Javier; Aller, Rocio; Ampuero, Javier; Arias-Loste, Maria Teresa; Augustin, Salvador; Calleja, Jose Luis; Crespo, Javier; Escudero, Amparo; Gonzalo Benito, Hugo; Hernandez Conde, Marta et al. DOI: 10.1111/liv.15323
PMID: 35635535 Journal: LIVER INTERNATIONAL Year: 2022 Reference: Liver Int. 2022 Aug;42(8):1751-1761. doi: 10.1111/liv.15327. Epub 2022 Jun 14. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Colom, Joan; Egea-Cortes, Laia; Gomez I Prat, Jordi; Majo, Xavier; Martro, Elisa; Not, Anna; Ouaarab, Hakima; Reyes-Urena, Juliana; Roade, Luisa et al. DOI: 10.1111/liv.15327
PMID: 35625751 Journal: Biomedicines Year: 2022 Reference: Biomedicines. 2022 Apr 28;10(5). pii: biomedicines10051015. doi: 10.3390/biomedicines10051015. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Ciudin, Andreea; Ferrer-Costa, Roser; Gabriel-Medina, Pablo; Pericas, Juan M; Rivera-Esteban, Jesus; Rodriguez-Frias, Francisco; Selva, David Martinez et al. DOI: 10.3390/biomedicines10051015
PMID: 35625927 Journal: Biomedicines Year: 2022 Reference: Biomedicines. 2022 May 20;10(5). pii: biomedicines10051191. doi: 10.3390/biomedicines10051191. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Barbera, Aurora; Bolca, Selin; de Leeuw, Marcel; Estrella, Federico; Genesca, Joan; Gottardi, Davide; Horscroft, Nigel; Martell, Maria; Pinheiro, Iris et al. DOI: 10.3390/biomedicines10051191
PMID: 34003542 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2021 Reference: J Viral Hepat. 2021 Aug;28(8):1177-1189. doi: 10.1111/jvh.13545. Epub 2021 Jun 8. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Cortez-Pinto, Helena; Dahl, Elin Hoffmann; Dalgard, Olav; de Martel, Catherine; Duffell, Erika; Hadzhilova, Tnaiq; Katzarov, Krum; Mardh, Otilia; Mozalevskis, Antons et al. DOI: 10.1111/jvh.13545
PMID: 33982942 Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY Year: 2021 Reference: Am J Gastroenterol. 2021 Apr;116(4):723-732. doi: 10.14309/ajg.0000000000000994. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Augustin, Salvador; Berzigotti, Annalisa; Bosch, Jaime; Bureau, Christophe; Ferlitsch, Arnulf; Genesca, Joan; Guillaume, Maeva; Ma, Mang M; Mandorfer, Mattias et al. DOI: 10.14309/ajg.0000000000000994
PMID: 33916702 Journal: Viruses-Basel Year: 2021 Reference: Viruses. 2021 Apr 3;13(4). pii: v13040616. doi: 10.3390/v13040616. Impact factor: Publication type: Review in international publication Authors: Briones, Carlos; de Avila, Ana Isabel; Domingo, Esteban; Gallego, Isabel; Garcia-Crespo, Carlos; Gomez, Jordi; Gregori, Josep; Lobo-Vega, Rebeca; Martinez-Gonzalez, Brenda; Moreno, Elena et al. DOI: 10.3390/v13040616
PMID: 33923569 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Apr 16;10(8). pii: jcm10081724. doi: 10.3390/jcm10081724. Impact factor: Publication type: Paper in international publication Authors: Barrecheguren, Miriam; Belmonte, Irene; Calle, Myriam; Esquinas, Cristina; Genesca, Joan; Miravitlles, Marc; Nunez, Alexa; Pons, Monica; Rodriguez, Esther; Rodriguez-Frias, Francisco et al. DOI: 10.3390/jcm10081724
PMID: 32339602 Journal: JOURNAL OF HEPATOLOGY Year: 2020 Reference: J Hepatol. 2020 Nov;73(5):1082-1091. doi: 10.1016/j.jhep.2020.04.024. Epub 2020 Apr 24. Impact factor: Publication type: Paper in international publication Authors: Abraldes, J G; Albillos, A; Alvarado, E; Amitrano, L; Banares, R; Barcelo, R; Bosch, J; Brol, M; Bureau, C; Calleja, J L et al. DOI: 10.1016/j.jhep.2020.04.024
PMID: 32329119 Journal: LIVER INTERNATIONAL Year: 2020 Reference: Liver Int. 2020 Aug;40(8):1906-1916. doi: 10.1111/liv.14489. Epub 2020 Jun 3. Impact factor: Publication type: Paper in international publication Authors: Barreira-Diaz, Ana; Buti, Maria; Castells, Lluis; Esteban, Rafael; Martinez-Valle, Fernando; Minguez, Beatriz; Munoz-Couselo, Eva; Ortiz-Velez, Carolina; Riveiro-Barciela, Mar; Vidal-Gonzalez, Judit et al. DOI: 10.1111/liv.14489
PMID: 31816146 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2020 Reference: J Viral Hepat. 2020 Apr;27(4):453-455. doi: 10.1111/jvh.13245. Epub 2019 Dec 18. Impact factor: Publication type: Paper in international publication Authors: Bonis Puig, Sara; Genesca Ferrer, Joan; Martinez-Camprecios, Joan; Minguez Rosique, Beatriz; Pons Delgado, Monica; Salcedo Allende, Maria Teresa et al. DOI: 10.1111/jvh.13245
PMID: 32289870 Journal: LIVER TRANSPLANTATION Year: 2020 Reference: Liver Transpl. 2020 Sep;26(9):1121-1126. doi: 10.1002/lt.25778. Epub 2020 Aug 4. Impact factor: Publication type: Paper in international publication Authors: Bilbao, Itxarone; Caralt, Mireia; Castells, Lluis; Len, Oscar; Los-Arcos, Ibai; Lung, Mayli; Nuvials, Xavier; Perez-Cameo, Cristina; Pont, Teresa; Vargas, Victor et al. DOI: 10.1002/lt.25778
PMID: 30014491 Journal: HEPATOLOGY Year: 2019 Reference: Hepatology. 2019 Jan;69(1):455-457. doi: 10.1002/hep.30180. Epub 2018 Dec 28. Impact factor: Publication type: Paper in international publication Authors: Alvarado, Edilmar; Flavia, Montse; Gely, Cristina; Guarner, Carlos; Poca, Maria; Roman, Eva; Soriano, German; Vargas, Victor et al. DOI: 10.1002/hep.30180
PMID: 30324553 Journal: DIGESTIVE DISEASES AND SCIENCES Year: 2019 Reference: Dig Dis Sci. 2019 Jan;64(1):285-286. doi: 10.1007/s10620-018-5294-y. Impact factor: Publication type: Letter or abstract Authors: Ahn, Sang Hoon; Buti, Maria; Caruntu, Florin A; Chan, Alain; Chan, Henry L Y; Chuang, Wan-Long; Crans, Gerald; Elkhashab, Magdy; Flisiak, Robert; Fung, Scott et al. DOI: 10.1007/s10620-018-5294-y
PMID: 30451649 Journal: JOURNAL OF GENERAL VIROLOGY Year: 2019 Reference: J Gen Virol. 2019 Jan;100(1):63-68. doi: 10.1099/jgv.0.001175. Epub 2018 Nov 19. Impact factor: Publication type: Paper in international publication Authors: Caro-Perez, Noelia; Crespo, Gonzalo; Esteban, Juan Ignacio; Forns, Xavier; Gambato, Martina; Garcia-Cehic, Damir; Garcia-Gonzalez, Neris; Gonzalez, Patricia; Gonzalez-Candelas, Fernando; Gregori, Josep et al. DOI: 10.1099/jgv.0.001175
PMID: 30576297 Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Year: 2019 Reference: Eur J Gastroenterol Hepatol. 2019 Feb;31(2):267-271. doi: 10.1097/MEG.0000000000001289. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Calleja, Jose L; Casado, Marta; Casanovas, Teresa; Crespo, Javier; Diago, Moises; Figueruela, Blanca; Fuentes, Javier; Gomez-Rodriguez, Rafael; Molina, Esther et al. DOI: 10.1097/MEG.0000000000001289
PMID: 29427500 Journal: LIVER INTERNATIONAL Year: 2018 Reference: Liver Int. 2018 Feb;38 Suppl 1:84-89. doi: 10.1111/liv.13641. Impact factor: Publication type: Review in national publication Authors: Buti, Maria; Esteban, Rafael; Riveiro-Barciela, Mar et al. DOI: 10.1111/liv.13641
PMID: 29427368 Journal: LIVER INTERNATIONAL Year: 2018 Reference: Liver Int. 2018 Oct;38(10):1760-1769. doi: 10.1111/liv.13716. Epub 2018 Mar 6. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Edwards, Rosalind; Gaggar, Anuj; Gane, Ed; Jackson, Kathy; Janssen, Harry; Kitrinos, Kathryn; Littlejohn, Margaret; Locarnini, Stephen; Marcellin, Patrick et al. DOI: 10.1111/liv.13716
PMID: 29427727 Journal: JOURNAL OF HEPATOLOGY Year: 2018 Reference: J Hepatol. 2018 Jun;68(6):1129-1136. doi: 10.1016/j.jhep.2018.01.031. Epub 2018 Feb 8. Impact factor: Publication type: Paper in international publication Authors: Berg, Thomas; Buti, Maria; Chi, Heng; Colombo, Massimo; Dalekos, George; de la Revilla, Juan; Esteban, Rafael; Galanis, Kostantinos; Gatselis, Nikolaos; Goulis, John et al. DOI: 10.1016/j.jhep.2018.01.031
PMID: 29253705 Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Year: 2018 Reference: Int J Infect Dis. 2018 Feb;67:114-117. doi: 10.1016/j.ijid.2017.12.016. Epub 2017 Dec 15. Impact factor: Publication type: Paper in international publication Authors: Bernal, Samuel; Del Campo, Jose A; Figueruela, Blanca; Garcia-Rey, Silvia; Grande, Lourdes; Gregori, Josep; Palomares, Jose C; Parra-Sanchez, Manuel; Quer, Josep; Romero-Gomez, Manuel et al. DOI: 10.1016/j.ijid.2017.12.016
PMID: 28273410 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2017 Reference: J Viral Hepat. 2017 Sep;24(9):750-758. doi: 10.1111/jvh.12704. Epub 2017 Apr 18. Impact factor: Publication type: Paper in international publication Authors: Buti, M; Casado, M A; Dominguez-Hernandez, R; Esteban, R; Oyaguez, I et al. DOI: 10.1111/jvh.12704
PMID: 28252637 Journal: Nature Reviews Disease Primers Year: 2017 Reference: Nat Rev Dis Primers. 2017 Mar 2;3:17006. doi: 10.1038/nrdp.2017.6. Impact factor: Publication type: Review in national publication Authors: Buti, Maria; Gane, Ed; Manns, Michael P; Pawlotsky, Jean-Michel; Razavi, Homie; Terrault, Norah; Younossi, Zobair et al. DOI: 10.1038/nrdp.2017.6
PMID: 28238958 Journal: Clinical Gastroenterology and Hepatology Year: 2017 Reference: Clin Gastroenterol Hepatol. 2017 Jun;15(6):945-949.e1. doi: 10.1016/j.cgh.2017.02.020. Epub 2017 Feb 24. Impact factor: Publication type: Paper in international publication Authors: Ampuero, Javier; Arenas, Juan; Buti, Maria; Cabezas, Joaquin; Calleja, Jose Luis; Crespo, Javier; Fernandez, Inmaculada; Garcia-Samaniego, Javier; Gea, Francisco; Hernandez-Conde, Marta et al. DOI: 10.1016/j.cgh.2017.02.020
PMID: 28215615 Journal: Clinical Gastroenterology and Hepatology Year: 2017 Reference: Clin Gastroenterol Hepatol. 2017 Jul;15(7):1087-1094.e2. doi: 10.1016/j.cgh.2017.01.032. Epub 2017 Feb 12. Impact factor: Publication type: Paper in international publication Authors: Afdhal, Nezam; Akarca, Ulus Salih; Buti, Maria; Flaherty, John F; Flisiak, Robert; Jacobson, Ira M; Marcellin, Patrick; McHutchison, John G; Myers, Robert P; Patel, Keyur et al. DOI: 10.1016/j.cgh.2017.01.032
PMID: 26992700 Journal: ALCOHOL Year: 2016 Reference: Alcohol. 2016 Mar;51:51-6. doi: 10.1016/j.alcohol.2016.01.002. Epub 2016 Feb 4. Impact factor: Publication type: Paper in international publication Authors: Altamirano, Jose; Blanch, Jose Luis; Gual, Antoni; Lligona, Anna; Lopez-Pelayo, Hugo; Miquel, Laia et al. DOI: 10.1016/j.alcohol.2016.01.002
PMID: 26946155 Journal: JOURNAL OF CLINICAL VIROLOGY Year: 2016 Reference: J Clin Virol. 2016 May;78:14-9. doi: 10.1016/j.jcv.2016.02.024. Epub 2016 Feb 28. Impact factor: Publication type: Paper in international publication Authors: Ausina, Vicente; Bascunana, Elisabet; Esteban, Juan Ignacio; Garcia-Cehic, Damir; Gregori, Josep; Martro, Elisa; Quer, Josep; Saludes, Veronica et al. DOI: 10.1016/j.jcv.2016.02.024
PMID: 26516761 Journal: HEPATOLOGY Year: 2016 Reference: Hepatology. 2016 Feb;63(2):488-98. doi: 10.1002/hep.28321. Epub 2016 Jan 4. Impact factor: Publication type: Paper in international publication Authors: Abradelo, M; Abradelo, Manuel; Aguero, F; Aguero, F; Aguero, Fernando; Aguilera, V; Aguilera, Victoria; Alonso, M P; Antela, A; Araiz, J J et al. DOI: 10.1002/hep.28321
PMID: 26778768 Journal: Gastroenterologia y Hepatologia Year: 2016 Reference: Gastroenterol Hepatol. 2016 Nov;39(9):607-626. doi: 10.1016/j.gastrohep.2015.09.019. Epub 2016 Jan 8. Impact factor: Publication type: Paper in international publication Authors: Aracil, Carles; Cinta Cardona, Maria; Coll, Susanna; Fernandez, Javier; Genesca, Joan; Gines, Pere; Hombrados, Manoli; Martin-Llahi, Marta; Morillas, Rosa; Pardo, Albert et al. DOI: 10.1016/j.gastrohep.2015.09.019
PMID: 24637729 Journal: J CLIN GASTROENTEROL Year: 2015 Reference: J Clin Gastroenterol. 2015 Feb;49(2):165-8. doi: 10.1097/MCG.0000000000000113. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Girones, Rosa; Minguez, Beatriz; Quer, Josep; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco et al. DOI: 10.1097/MCG.0000000000000113
PMID: 24517276 Journal: LIVER INT Year: 2015 Reference: Liver Int. 2015 Feb;35(2):326-34. doi: 10.1111/liv.12472. Epub 2014 Feb 12. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Esteban, Rafael; Ezkurdia, Nahia; Genesca, Joan; Martell, Maria; Raurell, Imma; Rodriguez, Sarai et al. DOI: 10.1111/liv.12472
PMID: 25070519 Journal: MEDICINA CLINICA Year: 2015 Reference: Med Clin (Barc). 2015 Mar 9;144(5):239. doi: 10.1016/j.medcli.2014.04.019. Epub 2014 Jul 26. Impact factor: 1.417 Publication type: Letter or abstract Authors: Santafe Colomina, Manel, Roade Tato, Luisa, Callejas Moraga, Eduardo L, Pinal Fernandez, Iago et al. DOI: 10.1016/j.medcli.2014.04.019
PMID: 26395289 Journal: JOURNAL OF GENERAL VIROLOGY Year: 2015 Reference: J Gen Virol. 2015 Dec;96(12):3493-3498. doi: 10.1099/jgv.0.000289. Impact factor: 3.183 Publication type: Paper in international publication Authors: Casillas, Rosario, Perez-Del-Pulgar, Sofia, Gregori, Josep, Rodriguez-Frias, Francisco, Gonzalez, Patricia, Garcia-Cehic, Damir, Ramirez, Santseharay, Forns, Xavier, Quer, Josep, Esteban, Juan I et al. DOI: 10.1099/jgv.0.000289
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
