About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37716616 Journal: Clinical Gastroenterology and Hepatology Year: 2023 Reference: Clin Gastroenterol Hepatol. 2023 Sep 14:S1542-3565(23)00708-5. doi: 10.1016/j.cgh.2023.08.038. Impact factor: Publication type: Paper in international publication Authors: Aigner, Elmar; Amzou, Samira; Bals, Robert; Benini, Federica; Bewersdorf, Lisa; Burbaum, Barbara; Denk, Helmut; Frankova, Sona; Fraughen, Daniel D; Fromme, Malin et al. DOI: 10.1016/j.cgh.2023.08.038
PMID: 37734683 Journal: JOURNAL OF HEPATOLOGY Year: 2023 Reference: J Hepatol. 2023 Sep 19:S0168-8278(23)05096-1. doi: 10.1016/j.jhep.2023.09.011. Impact factor: Publication type: Paper in international publication Authors: Ahn, Sang Hoon; Berg, Thomas; Buti, Maria; Buti, Maria; Calleja, Jose Luis; Chun, Ho Soo; Dalekos, George N; Goulis, John; Janssen, Harry LA; Jun, Dae Won et al. DOI: 10.1016/j.jhep.2023.09.011
PMID: 37745192 Journal: JHEP Reports Year: 2023 Reference: JHEP Rep. 2023 Jul 13;5(10):100842. doi: 10.1016/j.jhepr.2023.100842. eCollection 2023 Oct. Impact factor: Publication type: Paper in international publication Authors: Berg, Thomas; Bes, Marta; Buti, Maria; Buti, Maria; Casillas, Rosario; Esteban, Rafael; Esteban, Rafael; Esteban, Rafael; Palom, Adriana; Pfefferkorn, Maria et al. DOI: 10.1016/j.jhepr.2023.100842
PMID: 37769952 Journal: Gastroenterology Year: 2023 Reference: Gastroenterology. 2023 Sep 26:S0016-5085(23)05068-0. doi: 10.1053/j.gastro.2023.09.033. Impact factor: Publication type: Paper in international publication Authors: Agarwal, K; Ahn, S H; Berg, T; Boonstra, A; Brakenhoff, S M; Brunetto, M; Buti, M; Buti, M; Carey, I; Chen, C-H et al. DOI: 10.1053/j.gastro.2023.09.033
PMID: 35625927 Journal: Biomedicines Year: 2022 Reference: Biomedicines. 2022 May 20;10(5). pii: biomedicines10051191. doi: 10.3390/biomedicines10051191. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Barbera, Aurora; Bolca, Selin; de Leeuw, Marcel; Estrella, Federico; Genesca, Joan; Gottardi, Davide; Horscroft, Nigel; Martell, Maria; Pinheiro, Iris et al. DOI: 10.3390/biomedicines10051191
PMID: 35474447 Journal: United European Gastroenterology Journal Year: 2022 Reference: United European Gastroenterol J. 2022 May;10(4):435-437. doi: 10.1002/ueg2.12230. Epub 2022 Apr 26. Impact factor: Publication type: Letter or abstract Authors: Botos, Andreea; Bretthauer, Michael; Burra, Patrizia; Buti Ferret, Maria; Dugic, Ana; Fracasso, Pierluigi; Leja, Marcis; Matysiak Budnik, Tamara; Michl, Patrick; Ricciardiello, Luigi et al. DOI: 10.1002/ueg2.12230
PMID: 35488821 Journal: Revista Espanola de Quimioterapia Year: 2022 Reference: Rev Esp Quimioter. 2022 Apr;35 Suppl 1:28-30. doi: 10.37201/req/s01.06.2022. Epub 2022 Apr 22. Impact factor: Publication type: Review in international publication Authors: Cilloniz, C; Pericas, J M; Rojas, J et al. DOI: 10.37201/req/s01.06.2022
PMID: 35616885 Journal: CLINICAL DRUG INVESTIGATION Year: 2022 Reference: Clin Drug Investig. 2022 Jun;42(Suppl 1):3. doi: 10.1007/s40261-022-01167-1. Impact factor: Publication type: Letter or abstract Authors: Lledo-Navarro, Jose Luis; Minguez, Beatriz et al. DOI: 10.1007/s40261-022-01167-1
PMID: 32780526 Journal: HEPATOLOGY Year: 2021 Reference: Hepatology. 2021 May;73(5):1652-1670. doi: 10.1002/hep.31516. Impact factor: Publication type: Paper in international publication Authors: Bayliss, Julianne; Buti Ferret, Maria; Chan, Henry L Y; Colledge, Danni; Feierbach, Becket; Gaggar, Anuj; Gane, Ed; Howden, Benjamin P; Jackson, Kathy; Janssen, Harry L A et al. DOI: 10.1002/hep.31516
PMID: 33905794 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Sep;75(3):589-599. doi: 10.1016/j.jhep.2021.04.022. Epub 2021 Apr 24. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Albillos, Agustin; Alvarado, Edilmar; Aracil, Carles; Augustin, Salvador; Banares, Rafael; Bosch, Jaume; Brujats, Anna; Calleja, Jose L; Garcia-Pagan, Joan C et al. DOI: 10.1016/j.jhep.2021.04.022
PMID: 33896100 Journal: LIVER INTERNATIONAL Year: 2021 Reference: Liver Int. 2021 Sep;41(9):2076-2086. doi: 10.1111/liv.14898. Epub 2021 May 7. Impact factor: Publication type: Paper in international publication Authors: Abad, Javier; Aller, Rocio; Ampuero, Javier; Andrade, Raul J; Aspichueta, Patricia; Augustin, Salvador; Banales, Jesus M; Benlloch, Salvador; Caballeria, Joan; Crespo, Javier et al. DOI: 10.1111/liv.14898
PMID: 33054562 Journal: Global Health Promotion Year: 2021 Reference: Glob Health Promot. 2021 Mar;28(1):65-69. doi: 10.1177/1757975920962797. Epub 2020 Oct 15. Impact factor: Publication type: Paper in international publication Authors: Benach, Joan; Martinez-Herrera, Eliana; Molina-Betancur, Juan Camilo; Pericas, Juan M et al. DOI: 10.1177/1757975920962797
PMID: 32286105 Journal: Future Microbiology Year: 2020 Reference: Future Microbiol. 2020 Mar;15:349-364. doi: 10.2217/fmb-2019-0247. Impact factor: Publication type: Paper in international publication Authors: Escola-Verge, Laura; Fernandez-Hidalgo, Nuria; Pericas, Juan M et al. DOI: 10.2217/fmb-2019-0247
PMID: 32247593 Journal: TRANSPLANTATION PROCEEDINGS Year: 2020 Reference: Transplant Proc. 2020 Jun;52(5):1496-1499. doi: 10.1016/j.transproceed.2020.02.056. Epub 2020 Apr 1. Impact factor: Publication type: Paper in international publication Authors: Castells, Lluis; Charco, Ramon; Juamperez, Javier; Larrarte, Mauricio; Mercadal-Hally, Maria; Quintero, Jesus; Vidal, Lis et al. DOI: 10.1016/j.transproceed.2020.02.056
PMID: 32202078 Journal: Brain and Behavior Year: 2020 Reference: Brain Behav. 2020 May;10(5):e01596. doi: 10.1002/brb3.1596. Epub 2020 Mar 22. Impact factor: Publication type: Paper in international publication Authors: Auger, Cristina; Cardona, Ignasi; De Fabregues, Oriol; Palasi, Antoni; Quintana, Manuel; Vargas, Victor; Vinas, Jaume et al. DOI: 10.1002/brb3.1596
PMID: 31394283 Journal: Clinical Gastroenterology and Hepatology Year: 2020 Reference: Clin Gastroenterol Hepatol. 2020 Apr;18(4):963-973.e14. doi: 10.1016/j.cgh.2019.07.055. Epub 2019 Aug 5. Impact factor: Publication type: Paper in international publication Authors: Aagaard, N K; Albillos, A; Alessandria, C; Amoros, A; Angeli, P; Arroyo, V; Arteaga, M; Aziz, F; Banares, R; Campion, D et al. DOI: 10.1016/j.cgh.2019.07.055
PMID: 31882668 Journal: Scientific Reports Year: 2019 Reference: Sci Rep. 2019 Dec 27;9(1):20183. doi: 10.1038/s41598-019-56366-2. Impact factor: 4.011 Publication type: Paper in international publication Authors: Hide, Diana, Fernandez-Iglesias, Anabel, Gil, Mar, Barbera, Aurora, Salcedo, Maria Teresa, Augustin, Salvador, Genesca, Joan, Martell, Maria, Raurell, Imma, Bravo, Miren et al. DOI: 10.1038/s41598-019-56366-2
PMID: 31694971 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2019 Reference: J Clin Microbiol. 2019 Dec 23;58(1). pii: JCM.01815-19. doi: 10.1128/JCM.01815-19. Print 2019 Dec 23. Impact factor: 4.959 Publication type: Paper in international publication Authors: Quer, Josep, Casis-Saez, Ernesto, Rodriguez-Frias, Francisco, Esteban-Mur, Rafael, Buti-Ferret, Maria, Ferrer-Costa, Roser, Lopez-Martinez, Rosa, Arias-Garcia, Andrea, Rodriguez-Algarra, Francisco, Castellote-Belles, Laura et al. DOI: 10.1128/JCM.01815-19
PMID: 31666360 Journal: JOURNAL OF CLINICAL MICROBIOLOGY Year: 2019 Reference: J Clin Microbiol. 2019 Dec 23;58(1). pii: JCM.01379-19. doi: 10.1128/JCM.01379-19. Print 2019 Dec 23. Impact factor: 4.959 Publication type: Letter or abstract Authors: Rando-Segura, Ariadna, Buti, Maria, Quer, Josep, Lopez-Martinez, Rosa, Rodriguez-Frias, Francisco et al. DOI: 10.1128/JCM.01379-19
PMID: 31571936 Journal: Infection and Drug Resistance Year: 2019 Reference: Infect Drug Resist. 2019 Sep 10;12:2799-2807. doi: 10.2147/IDR.S214735. eCollection 2019. Impact factor: 3 Publication type: Paper in international publication Authors: Amer, Fatma, Yousif, Monkez M, Hammad, Noha M, Garcia-Cehic, Damir, Gregori, Josep, Rando-Segura, Ariadna, Nieto-Aponte, Leonardo, Esteban, Juan Ignacio, Rodriguez-Frias, Francisco, Quer, Josep et al. DOI: 10.2147/IDR.S214735
PMID: 29397419 Journal: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY Year: 2018 Reference: Eur Biophys J. 2018 May;47(4):443-457. doi: 10.1007/s00249-018-1282-6. Epub 2018 Feb 3. Impact factor: Publication type: Paper in international publication Authors: Domingo, Esteban; Perales, Celia et al. DOI: 10.1007/s00249-018-1282-6
PMID: 29395458 Journal: JOURNAL OF HEPATOLOGY Year: 2018 Reference: J Hepatol. 2018 Mar;68(3):630. doi: 10.1016/j.jhep.2017.12.017. Epub 2018 Feb 1. Impact factor: Publication type: Letter or abstract Authors: Abbadi, Reyad; Adebayo, Danielle; Angeli, Paolo; Borisenko, Oleg; Bureau, Christophe; Cordoba, Juan; de Rieu, Mael Chalret; Elkrief, Laure; Inhaber, Neil; Jalan, Rajiv et al. DOI: 10.1016/j.jhep.2017.12.017
PMID: 29383024 Journal: Therapeutic Advances in Gastroenterology Year: 2018 Reference: Therap Adv Gastroenterol. 2017 Nov 26;11:1756283X17743419. doi: 10.1177/1756283X17743419. eCollection 2018. Impact factor: Publication type: Paper in international publication Authors: Ampuero, Javier; Carmona, Isabel; Genesca, Joan; Les, Inigo; Moreno, Carolina; Romero-Gomez, Manuel; Sanpedro, Francesc; Simon-Talero, Macarena; Ventura-Cots, Meritxell et al. DOI: 10.1177/1756283X17743419
PMID: 29360462 Journal: GASTROENTEROLOGY Year: 2018 Reference: Gastroenterology. 2018 May;154(6):1694-1705.e4. doi: 10.1053/j.gastro.2018.01.028. Epub 2018 Jan 31. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Albillos, Agustin; Augustin, Salvador; Baiges, Anna; Banares, Rafael; Belmonte, Ernest; Berbel, Claudia; Berzigotti, Annalisa; Ble, Michel; Botella, Enrique Ramon et al. DOI: 10.1053/j.gastro.2018.01.028
PMID: 27154504 Journal: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM Year: 2017 Reference: J Cereb Blood Flow Metab. 2017 Mar;37(3):927-937. doi: 10.1177/0271678X16649196. Epub 2016 Jul 20. Impact factor: Publication type: Paper in international publication Authors: Bove, Jordi; Chavarria, Laia; Cordoba, Juan; Garcia-Lezana, Teresa; Genesca, Joan; Oria, Marc; Romero-Gimenez, Jordi; Vila, Miquel et al. DOI: 10.1177/0271678X16649196
PMID: 27896822 Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS Year: 2017 Reference: Aliment Pharmacol Ther. 2017 Feb;45(3):468-475. doi: 10.1111/apt.13883. Epub 2016 Nov 29. Impact factor: Publication type: Clinical Trials Authors: Buti, M; Calleja, J L; Corbett, C; Crespo, J; Diago, M; Fevery, B; Jessner, W; Kalmeijer, R; Kurland, D; Lens, S et al. DOI: 10.1111/apt.13883
PMID: 27905173 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2017 Reference: J Viral Hepat. 2017 Jan;24(1):4-12. doi: 10.1111/jvh.12620. Epub 2016 Dec 1. Impact factor: Publication type: Review in international publication Authors: Buti, M; Esteban, R; Llaneras, J; Riveiro-Barciela, M et al. DOI: 10.1111/jvh.12620
PMID: 28188668 Journal: LIVER TRANSPLANTATION Year: 2017 Reference: Liver Transpl. 2017 May;23(5):645-651. doi: 10.1002/lt.24741. Impact factor: Publication type: Paper in international publication Authors: Abradelo, Manuel; Aguero, Fernando; Aguilera, Victoria; Barcena, Rafael; Barrera-Baena, Pilar; Bilbao, Itxarone; Blanes, Marino; Castells, Lluis; Del Campo, Santos; Fabregat, Juan et al. DOI: 10.1002/lt.24741
PMID: 26902945 Journal: JOURNAL OF HEPATOLOGY Year: 2016 Reference: J Hepatol. 2016 Jun;64(6):1428-45. doi: 10.1016/j.jhep.2016.02.020. Epub 2016 Feb 21. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Juan G; Altamirano, Jose; Berg, Thomas; Duarte-Rojo, Andres; van Bommel, Florian; Villanueva, Augusto; Wiegand, Johannes et al. DOI: 10.1016/j.jhep.2016.02.020
PMID: 26890629 Journal: LIVER TRANSPLANTATION Year: 2016 Reference: Liver Transpl. 2016 Apr;22(4):446-58. doi: 10.1002/lt.24416. Impact factor: Publication type: Paper in international publication Authors: Bahirwani, Ranjeeta; Berg, Christoph; Brown, Robert S; Castells, Lluis; Chacko, Kristina R; Durand, Christine M; ElSharkawy, Ahmed M; Emond, Bruno; Ferenci, Peter; Fontana, Robert J et al. DOI: 10.1002/lt.24416
PMID: 26284943 Journal: LIVER INTERNATIONAL Year: 2016 Reference: Liver Int. 2016 Feb;36(2):177-80. doi: 10.1111/liv.12941. Impact factor: 4.47 Publication type: Editorail in international publication Authors: Ventura-Cots, Meritxell, Santos, Begona, Genesca, Joan et al. DOI: 10.1111/liv.12941
PMID: 27920481 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2016 Reference: World J Gastroenterol. 2016 Nov 21;22(43):9604-9612. Impact factor: 2.787 Publication type: Paper in international publication Authors: Chen, Qian, Belmonte, Irene, Buti, Maria, Nieto, Leonardo, Garcia-Cehic, Damir, Gregori, Josep, Perales, Celia, Ordeig, Laura, Soria, Maria Eugenia, Esteban, Rafael et al. DOI: 10.3748/wjg.v22.i43.9604
PMID: 25160690 Journal: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Year: 2015 Reference: J Gastroenterol Hepatol. 2015 Jan;30(1):92-8. doi: 10.1111/jgh.12712. Impact factor: 3.504 Publication type: Paper in international publication Authors: Cossio-Gil, Yolima, Martinez-Gomez, Xavier, Campins-Marti, Magda, Rodrigo-Pendas, Jose Angel, Borruel-Sainz, Natalia, Rodriguez-Frias, Francisco, Casellas-Jorda, Francesc et al. DOI: 10.1111/jgh.12712
PMID: 26714168 Journal: PLoS One Year: 2015 Reference: PLoS One. 2015 Dec 29;10(12):e0144816. doi: 10.1371/journal.pone.0144816. eCollection 2015. Impact factor: 3.234 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Caballero, Andrea, Gregori, Josep, Homs, Maria, Tabernero, David, Gonzalez, Carolina, Quer, Josep, Blasi, Maria, Casillas, Rosario, Nieto, Leonardo et al. DOI: 10.1371/journal.pone.0144816
PMID: 25641570 Journal: Transplant Infectious Disease Year: 2015 Reference: Transpl Infect Dis. 2015 Apr;17(2):208-20. doi: 10.1111/tid.12360. Impact factor: 2.064 Publication type: Paper in international publication Authors: Buti, M, Tabernero, D, Mas, A, Homs, M, Prieto, M, Rodriguez-Frias, F, Casafont, F, Casillas, R, Gonzalez, A, Miras, M et al. DOI: 10.1111/tid.12360
PMID: 25967352 Journal: JOURNAL OF VIRAL HEPATITIS Year: 2015 Reference: J Viral Hepat. 2015 Sep;22(9):683-90. doi: 10.1111/jvh.12419. Epub 2015 May 13. Impact factor: 3.909 Publication type: Paper in international publication Authors: Buti, M, Llaneras, J, Riveiro-Barciela, M, Esteban, R et al. DOI: 10.1111/jvh.12419
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
