Skip to main content

Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

A step-by-step guide to ileoanal J-pouch MRI interpretation.

PMID: 38066348
Journal: Techniques in Coloproctology
Year: 2023
Reference: Tech Coloproctol. 2023 Dec 8;28(1):2. doi: 10.1007/s10151-023-02888-x.
Impact factor:
Publication type: Paper in international publication
Authors: Celentano, V; Climente, Monica; Damani, A; Escolano, Angel; Kennedy, N; Lee, Y J; Manrique-Rodriguez, Silvia; Manzo, C A; Miarons, Marta; Parra, Alba Pau et al.
DOI: 10.1007/s10151-023-02888-x

Donor-Derived Cell-Free DNA: Attractive Biomarker Seeks a Context of Use.

PMID: 38106814
Journal: TRANSPLANT INTERNATIONAL
Year: 2023
Reference: Transpl Int. 2023 Dec 1;36:12406. doi: 10.3389/ti.2023.12406. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Benet, Marta; Bestard, Oriol; Carbonell, Teresa; Del Carmen, Amin; Farres, Montserrat Girabent; Garnacho-Castano, Manuel V; Garrido, Ainoa Biurrun; Jerez-Molina, Carmen; Miravitlles, Marc; Molina-Raya, Lorena et al.
DOI: 10.3389/ti.2023.12406

Preventing chronic malnutrition in children under 2 years in rural Angola (MuCCUA trial): protocol for the economic evaluation of a three-arm community cluster randomised controlled trial.

PMID: 38110392
Journal: BMJ Open
Year: 2023
Reference: BMJ Open. 2023 Dec 18;13(12):e073349. doi: 10.1136/bmjopen-2023-073349.
Impact factor:
Publication type: Paper in international publication
Authors: Aguado, Isabel; Biondani, Andrea; Cavero, Teresa; Chaperon, Frederique; Custodio, Estefania; Daina, Erica; Eisenberger, Ute; Faria, Lourdes Maria; Gackler, Anja; Garcia-Carro, Clara et al.
DOI: 10.1136/bmjopen-2023-073349

Staged treatment of bicondylar tibial plateau fractures: influence of frame configuration and quality of reduction on outcomes.

PMID: 38110517
Journal: European Journal of Trauma and Emergency Surgery
Year: 2023
Reference: Eur J Trauma Emerg Surg. 2023 Dec 18. doi: 10.1007/s00068-023-02411-9.
Impact factor:
Publication type: Paper in international publication
Authors: Andres-Peiro, Jose Vicente; Bestard, Oriol; Corro, Sebastian; Garcia-Sanchez, Yaiza; Guerra-Farfan, Ernesto Melchor; Naesens, Maarten; Oleo-Taltavull, Rafael; Pagliazzi, Angelica; Piedra-Calle, Carlos Alberto; Porcel-Vazquez, Juan Antonio et al.
DOI: 10.1007/s00068-023-02411-9

Humoral Response to Third Dose of SARS-CoV-2 Vaccines in the CKD Spectrum.

PMID: 35551070
Journal: Clinical Journal of the American Society of Nephrology
Year: 2022
Reference: Clin J Am Soc Nephrol. 2022 Jun;17(6):872-876. doi: 10.2215/CJN.01770222. Epub 2022 May 12.
Impact factor:
Publication type: Letter whit IF
Authors: Aguilar Cervera, Maria Cinta; Alfaro Sanchez, Christian; Arroyo, David; Carnerero Di Riso, Manuel Antonio; Cazorla, Juan Manuel; Cervienka, Michal; Cigarran Guldris, Secundino; de Arriba, Gabriel; de Sequera, Patricia; Folgueiras Lopez, Montserrat et al.
DOI: 10.2215/CJN.01770222

Minimal Change Disease Is Associated With Endothelial Glycocalyx Degradation and Endothelial Activation.

PMID: 35497798
Journal: Kidney International Reports
Year: 2022
Reference: Kidney Int Rep. 2021 Dec 16;7(4):797-809. doi: 10.1016/j.ekir.2021.11.037. eCollection 2022 Apr.
Impact factor:
Publication type: Paper in international publication
Authors: Banks, Mindy; Bauer, Colin; Bjornstad, Petter; Blaine, Judith; Cara-Fuentes, Gabriel; de Lucas-Collantes, Carmen; Johnson, Richard J; Lucia, Marshall Scott; Martinez, Cristina; Ordonez, Flor A et al.
DOI: 10.1016/j.ekir.2021.11.037

Is humoral and cellular response to SARS-CoV-2 vaccine modified by DMT in patients with multiple sclerosis and other autoimmune diseases?

PMID: 35475363
Journal: Multiple Sclerosis Journal
Year: 2022
Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27.
Impact factor:
Publication type: Paper in international publication
Authors: Agraz, Irene; Alvarez, Gary; Arrambide, Georgina; Bertran, Jordina; Bonastre, Merce; Carbonell-Mirabent, Pere; Cardenas-Robledo, Simon; Castillo, Joaquin; Castillo, Mireia; Cobo-Calvo, Alvaro et al.
DOI: 10.1177/13524585221089540

Acute kidney injury as a risk factor for mortality in oncological patients receiving check-point inhibitors.

PMID: 33547795
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Apr 25;37(5):887-894. doi: 10.1093/ndt/gfab034.
Impact factor:
Publication type: Paper in international publication
Authors: Agraz, Irene; Bolufer, Monica; Bury, Roxana; Cataneda, Zaira; Felip, Enriqueta; Gabaldon, Alejandra; Garcia-Carro, Clara; Jose Soler, Maria; Josep Carreras, Maria; Lorente, David et al.
DOI: 10.1093/ndt/gfab034

EFFECT OF RAMIPRIL ON KIDNEY, LUNG AND HEART ACE2 IN A DIABETIC MICE MODEL.

PMID: 33811970
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2021
Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111263. doi: 10.1016/j.mce.2021.111263. Epub 2021 Mar 31.
Impact factor:
Publication type: Paper in international publication
Authors: Benito, Begona; Dominguez-Baez, Pamela; Garcia-Carro, Clara; Jacobs-Cacha, Conxita; Molina-Van den Bosch, Mireia; Seron, Daniel; Soler, Maria Jose; Vergara, Ander et al.
DOI: 10.1016/j.mce.2021.111263

COVID-19 and its impact on the kidney and the nephrology community.

PMID: 33815779
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 26;14(Suppl 1):i1-i5. doi: 10.1093/ckj/sfab039. eCollection 2021 Mar.
Impact factor:
Publication type: Editorail in international publication
Authors: Batlle, Daniel; Soler, Maria Jose et al.
DOI: 10.1093/ckj/sfab039

Kidney transplantation and COVID-19 renal and patient prognosis.

PMID: 33815780
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 26;14(Suppl 1):i21-i29. doi: 10.1093/ckj/sfab030. eCollection 2021 Mar.
Impact factor:
Publication type: Review in international publication
Authors: Chamoun, Betty; Moreso, Francesc; Sellares, Joana; Seron, Daniel; Toapanta, Nestor; Torres, Irina B et al.
DOI: 10.1093/ckj/sfab030

Active bleeding after kidney biopsy: Successful ultrasound-guided direct thrombin embolization into the cortical fistula.

PMID: 33098132
Journal: JOURNAL OF CLINICAL ULTRASOUND
Year: 2021
Reference: J Clin Ultrasound. 2021 May;49(4):390-394. doi: 10.1002/jcu.22939. Epub 2020 Oct 24.
Impact factor:
Publication type: Letter or abstract
Authors: Bolufer Cardona, Monica; Escudero-Fernandez, Jose Miguel; Montealegre, Carolina; Perez Lafuente, Mercedes; Serres-Creixams, Xavier; Uriarte, Iciar et al.
DOI: 10.1002/jcu.22939

Consensus statement on the use of alemtuzumab in daily clinical practice in Spain.

PMID: 31987648
Journal: Neurologia (Barcelona, Spain)
Year: 2020
Reference: Neurologia (Engl Ed). 2020 Jan 25:S0213-4853(19)30146-X. doi: 10.1016/j.nrl.2019.11.003.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez Cermeno, J C; Arnal Garcia, C; Arroyo Gonzalez, R; Brieva Ruiz, L; Calles Hernandez, C; Eichau Madueno, S; Fernandez Fernandez, O; Fernandez-Prada, M; Garcia Merino, A; Garcia Vazquez, E et al.
DOI: 10.1016/j.nrl.2019.11.003

A Rejection Gene Expression Score in Indication and Surveillance Biopsies Is Associated with Graft Outcome.

PMID: 33153205
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2020
Reference: Int J Mol Sci. 2020 Nov 3;21(21). pii: ijms21218237. doi: 10.3390/ijms21218237.
Impact factor: 4.556
Publication type: Paper in international publication
Authors: Seron, Daniel, Moreso, Francesc, O'Valle, Francisco, Perello, Manel, Chamoun, Betty, Caraben, Anna, Torres, Irina B, Sellares, Joana, Jimenez, Raquel, Toapanta, Nestor et al.
DOI: 10.3390/ijms21218237

Impact of the COVID-19 pandemic on Spanish Nephrology Services.

PMID: 33131910
Journal: NEFROLOGIA
Year: 2020
Reference: Nefrologia. 2020 Nov - Dec;40(6):579-584. doi: 10.1016/j.nefro.2020.08.002. Epub 2020 Oct 6.
Impact factor: 1.544
Publication type: Editorial in national publication
Authors: Salgueira Lazo, Mercedes, Del Pino Y Pino, Maria Dolores, Ortiz, Alberto, Macia Heras, Manuel, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2020.08.002

SGLT2 inhibitors for non-diabetic kidney disease: drugs to treat CKD that also improve glycaemia.

PMID: 33123352
Journal: Clinical Kidney Journal
Year: 2020
Reference: Clin Kidney J. 2020 Oct 9;13(5):728-733. doi: 10.1093/ckj/sfaa198. eCollection 2020 Oct.
Impact factor: 3.388
Publication type: Editorail in international publication
Authors: Ortiz, Alberto, Gorriz, Jose Luis, Soler, Maria Jose, Fernandez-Fernandez, Beatriz, Sarafidis, Pantelis, Kanbay, Mehmet, Navarro-Gonzalez, Juan F et al.
DOI: 10.1093/ckj/sfaa198

Sex hormones and their influence on chronic kidney disease.

PMID: 30320621
Journal: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
Year: 2019
Reference: Curr Opin Nephrol Hypertens. 2019 Jan;28(1):1-9. doi: 10.1097/MNH.0000000000000463.
Impact factor: 3.013
Publication type: Paper in international publication
Authors: Soler, Maria Jose, Valdivielso, Jose Manuel, Jacobs-Cacha, Conxita et al.
DOI: 10.1097/MNH.0000000000000463

Is antibody-mediated rejection in kidney transplant recipients a risk factor for developing cytomegalovirus or BK virus infection? Results from a case-control study.

PMID: 30537648
Journal: JOURNAL OF CLINICAL VIROLOGY
Year: 2019
Reference: J Clin Virol. 2019 Jan;110:45-50. doi: 10.1016/j.jcv.2018.11.010. Epub 2018 Dec 1.
Impact factor: 3.02
Publication type: Paper in international publication
Authors: Len, Oscar, Perello, Manel, Torres, Irina B, Codina, Gemma, Esperalba, Juliana, Sellares, Joana, Moreso, Francesc, Seron, Daniel, Gavalda, Joan, Los-Arcos, Ibai et al.
DOI: 10.1016/j.jcv.2018.11.010

ACE2 and ACE in acute and chronic rejection after human heart transplantation.

PMID: 30314840
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2019
Reference: Int J Cardiol. 2019 Jan 15;275:59-64. doi: 10.1016/j.ijcard.2018.10.002. Epub 2018 Oct 3.
Impact factor: 3.471
Publication type: Paper in international publication
Authors: Perez-Villa, Felix, Mont, Lluis, Soler, Maria Jose, Batlle, Montserrat, Riera, Marta, Campos, Begona, Ortiz-Perez, Jose Tomas, Anguiano, Lidia, Roca-Ho, Heleia, Farrero, Marta et al.
DOI: 10.1016/j.ijcard.2018.10.002

Native ureteropyelostomy in the treatment of obstructive uropathy in adult renal transplant.

PMID: 24636074
Journal: ACTAS UROL ESP
Year: 2014
Reference: Actas Urol Esp. 2014 Oct;38(8):552-6. doi: 10.1016/j.acuro.2014.02.004. Epub 2014 Mar 11.
Impact factor: 1.148
Publication type: Paper in national publication
Authors: Celma, A, Cantarell, C, Moreso, F, Seron, D, Morote, J, Placer, J, Planas, J, Salvador, C, Lorente, D, Trilla, E et al.
DOI: 10.1016/j.acuro.2014.02.004

[Health related quality of life and kidney transplantation: A comparison with population values at 6 months post-transplant.]

PMID: 24480289
Journal: MED CLIN-BARCELONA
Year: 2014
Reference: Med Clin (Barc). 2014 May 6;142(9):393-6. doi: 10.1016/j.medcli.2013.09.044. Epub 2014 Jan 28.
Impact factor: 1.252
Publication type: Paper in national publication
Authors: Costa-Requena, Gema, Cantarell Aixendri, M Carmen, Rodriguez Urrutia, Amanda, Seron Micas, Daniel et al.
DOI: 10.1016/j.medcli.2013.09.044

The impact of the prevention strategies on the indirect effects of CMV infection in solid organ transplant recipients.

PMID: 24602805
Journal: TRANSPLANT REV-ORLAN
Year: 2014
Reference: Transplant Rev (Orlando). 2014 Apr;28(2):84-91. doi: 10.1016/j.trre.2014.01.001. Epub 2014 Jan 27.
Impact factor: 2.66
Publication type: Review in international publication
Authors: Roman, Antonio, Manito, Nicolas, Campistol, Josep Maria, Cuervas-Mons, Valentin, Almenar, Luis, Arias, Manuel, Casafont, Fernando, Del Castillo, Domingo, Crespo-Leiro, Maria G, Delgado, Juan F et al.
DOI: 10.1016/j.trre.2014.01.001

[Value of soluble urokinase receptor serum levels in the differential diagnosis between idiopathic and secondary focal segmental glomerulosclerosis].

PMID: 24463863
Journal: NEFROLOGIA
Year: 2014
Reference: Nefrologia. 2014;34(1):53-61. doi: 10.3265/Nefrologia.pre2013.Oct.12272.
Impact factor: 1.442
Publication type: Paper in national publication
Authors: Segarra, Alfons, Jatem, Elias, Quiles, M Teresa, Arbos, M Antonia, Ostos, Helena, Valtierra, Naiara, Carnicer, Clara, Salcedo, M Teresa et al.
DOI: 10.3265/Nefrologia.pre2013.Oct.12272

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.

The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.