About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 35211301 Journal: Clinical Kidney Journal Year: 2022 Reference: Clin Kidney J. 2021 Sep 28;15(3):417-424. doi: 10.1093/ckj/sfab176. eCollection 2022 Mar. Impact factor: 4.452 Publication type: Review in international publication Authors: Crespo, Marta, Rodriguez, Eva, Gabaldon, Alejandra, Soler, Maria Jose, Lop, Joan, Ribas, Andres, Puche, Adrian, Gimeno, Javier, Sans, Laia, Barrios, Clara et al. DOI: 10.1093/ckj/sfab176
PMID: 35171022 Journal: Microbiology Spectrum Year: 2022 Reference: Microbiol Spectr. 2022 Feb 23;10(1):e0178421. doi: 10.1128/spectrum.01784-21. Epub 2022 Feb 16. Impact factor: 7.171 Publication type: Paper in international publication Authors: Monforte, Arnau, Los-Arcos, Ibai, Martin-Gomez, Maria Teresa, Campany-Herrero, David, Sacanell, Judith, Berastegui, Cristina, Marquez-Algaba, Ester, Sempere, Abiu, Nuvials, Xavier, Castells, Lluis et al. DOI: 10.1128/spectrum.01784-21
PMID: 35053290 Journal: Biomolecules Year: 2022 Reference: Biomolecules. 2022 Jan 16;12(1). pii: biom12010143. doi: 10.3390/biom12010143. Impact factor: 4.879 Publication type: Review in international publication Authors: Llorens-Cebria, Carmen, Molina-Van den Bosch, Mireia, Vergara, Ander, Jacobs-Cacha, Conxita, Soler, Maria Jose et al. DOI: 10.3390/biom12010143
PMID: 34873314 Journal: Nature Reviews Nephrology Year: 2022 Reference: Nat Rev Nephrol. 2022 Feb;18(2):80-81. doi: 10.1038/s41581-021-00521-4. Impact factor: 28.314 Publication type: Review in international publication Authors: Soler, Maria Jose, Jacobs-Cacha, Conxita et al. DOI: 10.1038/s41581-021-00521-4
PMID: 33064917 Journal: Transplant Infectious Disease Year: 2021 Reference: Transpl Infect Dis. 2021 Apr;23(2):e13494. doi: 10.1111/tid.13494. Epub 2020 Oct 27. Impact factor: 2.228 Publication type: Paper in international publication Authors: Anaya, Fernando, Lopez-Hoyos, Marcos, Rodrigo, Emilio, Arias, Manuel, Perello, Manel, Seron, Daniel, Karanovic, Boris, Ezzahouri, Ikram, Mezzano, Sergio, Jaramillo, Maria et al. DOI: 10.1111/tid.13494
PMID: 33888348 Journal: NEFROLOGIA Year: 2021 Reference: Nefrologia (Engl Ed). 2021 Apr 19. pii: S0211-6995(21)00058-8. doi: 10.1016/j.nefro.2021.03.002. Impact factor: 2.033 Publication type: Letter or abstract Authors: LeonRoman, Juan, Vergara, Ander, Agraz, Irene, Garcia-Carro, Clara, Bermejo, Sheila, Gabaldon, Alejandra, Soler, Maria Jose et al. DOI: 10.1016/j.nefro.2021.03.002
PMID: 33887895 Journal: Minerva urology and nephrology Year: 2021 Reference: Minerva Urol Nephrol. 2021 Apr 22. pii: S2724-6051.21.04345-7. doi: 10.23736/S2724-6051.21.04345-7. Impact factor: 0 Publication type: Paper in international publication Authors: Miret, Enric, Moreso, Francesc, Toapanta, Nestor, Lorente, David, Triquell, Marina, Pont, Teresa, Perez-Hoyos, Santiago, Seron, Daniel, Morote, Juan, Trilla, Enrique et al. DOI: 10.23736/S2724-6051.21.04345-7
PMID: 33811970 Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY Year: 2021 Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111263. doi: 10.1016/j.mce.2021.111263. Epub 2021 Mar 31. Impact factor: 4.102 Publication type: Paper in international publication Authors: Soler, Maria Jose, Seron, Daniel, Garcia-Carro, Clara, Vergara, Ander, Jacobs-Cacha, Conxita, Molina-Van den Bosch, Mireia, Dominguez-Baez, Pamela, Benito, Begona et al. DOI: 10.1016/j.mce.2021.111263
PMID: 31865857 Journal: LUPUS Year: 2020 Reference: Lupus. 2020 Feb;29(2):118-125. doi: 10.1177/0961203319896018. Epub 2019 Dec 22. Impact factor: 2.251 Publication type: Paper in international publication Authors: Segarra, A, Arredondo, K V, Jaramillo, J, Jatem, E, Salcedo, M T, Agraz, I, Ramos, N, Carnicer, C, Valtierra, N, Ostos, E et al. DOI: 10.1177/0961203319896018
PMID: 31980684 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Jan 24;10(1):1159. doi: 10.1038/s41598-020-58197-y. Impact factor: 3.998 Publication type: Paper in international publication Authors: Jacobs-Cacha, Conxita, Puig-Gay, Natalia, Helm, Dominic, Rettel, Mandy, Sellares, Joana, Meseguer, Anna, Savitski, Mikhail M, Moreso, Francesc J, Soler, Maria Jose, Seron, Daniel et al. DOI: 10.1038/s41598-020-58197-y
PMID: 31895348 Journal: TRANSPLANTATION Year: 2020 Reference: Transplantation. 2020 May;104(5):911-922. doi: 10.1097/TP.0000000000003095. Impact factor: 4.264 Publication type: Paper in international publication Authors: Tullius, Stefan G, Schinstock, Carrie A, Mannon, Roslyn B, Budde, Klemens, Chong, Anita S, Haas, Mark, Knechtle, Stuart, Lefaucheur, Carmen, Montgomery, Robert A, Nickerson, Peter et al. DOI: 10.1097/TP.0000000000003095
PMID: 31913319 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Jan 8;10(1):26. doi: 10.1038/s41598-019-56856-3. Impact factor: 3.998 Publication type: Paper in international publication Authors: Garcia-Fernandez, Nuria, Mora-Gutierrez, Jose Maria, Rodriguez, Jose Antonio, Fernandez-Seara, Maria A, Orbe, Josune, Escalada, Francisco Javier, Soler, Maria Jose, Slon Roblero, Maria Fernanda, Riera, Marta, Paramo, Jose Antonio et al. DOI: 10.1038/s41598-019-56856-3
A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.
An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.
Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.
