About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 37813743 Journal: Nefrologia Year: 2023 Reference: Nefrologia (Engl Ed). 2023 Oct 7:S2013-2514(23)00146-3. doi: 10.1016/j.nefroe.2023.09.002. Impact factor: Publication type: Review in international publication Authors: Facila, Lorenzo; Gonzalez-Juanatey, Jose Ramon; Gorriz, Jose Luis; Ortiz, Alberto; Soler, Maria Jose; Valle, Alfonso et al. DOI: 10.1016/j.nefroe.2023.09.002
PMID: 37862791 Journal: Gynecologic Oncology Year: 2023 Reference: Gynecol Oncol. 2023 Oct 18;178:119-129. doi: 10.1016/j.ygyno.2023.09.012. Impact factor: Publication type: Paper in international publication Authors: Birrer, Michael; Boixadera, A; Castany-Aregall, M; Colombo, Nicoletta; Cristescu, Razvan; Distefano, L; Edmondson, Mackenzie; Garcia-Arumi, J; Garrell-Salat, X; Gonzalez-Martin, Antonio et al. DOI: 10.1016/j.ygyno.2023.09.012
PMID: 37879444 Journal: ANNALS OF ONCOLOGY Year: 2023 Reference: Ann Oncol. 2023 Oct 17:S0923-7534(23)04281-3. doi: 10.1016/j.annonc.2023.10.117. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Azuma, K; Baneras, Jordi; Barala, P; Bauml, J M; Bearz, A; Boixadera, Anna; Bourla, A B; Califano, R; Campelo, R G et al. DOI: 10.1016/j.annonc.2023.10.117
PMID: 37949757 Journal: Enfermeria intensiva Year: 2023 Reference: Enferm Intensiva (Engl Ed). 2023 Nov 8:S2529-9840(23)00057-5. doi: 10.1016/j.enfie.2023.06.002. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Al-Maghrabi, Reem; Alain, Sophie; Ballesteros-Reviriego, G; Beauvais, David; Bestard, Oriol; Bestard, Oriol; Blumberg, Emily; Boeken, Udo; Chemaly, Roy; Daniel Marti, J et al. DOI: 10.1016/j.enfie.2023.06.002
PMID: 35768070 Journal: AGE AND AGEING Year: 2022 Reference: Age Ageing. 2022 Aug 2;51(8). pii: 6609704. doi: 10.1093/ageing/afac157. Impact factor: Publication type: Editorail in international publication Authors: Fouque, Denis; Mattace-Raso, Francesco; Ortiz, Alberto; Soler, Maria Jose et al. DOI: 10.1093/ageing/afac157
PMID: 35757188 Journal: Kidney International Reports Year: 2022 Reference: Kidney Int Rep. 2022 Sep;7(9):2091-2096. doi: 10.1016/j.ekir.2022.06.007. Epub 2022 Jun 20. Impact factor: Publication type: Paper in international publication Authors: Arnol, Miha; Duivenvoorden, Raphael; Facundo, Carme; Franssen, Casper F M; Gansevoort, Ron T; Groeneveld, Marc; Hemmelder, Marc H; Hilbrands, Luuk B; Jager, Kitty J; Lepeytre, Fanny et al. DOI: 10.1016/j.ekir.2022.06.007
PMID: 33779754 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Jun 23;37(7):1270-1280. doi: 10.1093/ndt/gfab075. Impact factor: Publication type: Paper in international publication Authors: Allende, Natalia; Ariceta, Gema; Avila, Ana; Barros, Xoana; Bravo, Luis; Cabello, Virginia; Cano-Megias, Marta; Caravaca-Fontan, Fernando; Cruz, Sonia; Da Silva, Iara et al. DOI: 10.1093/ndt/gfab075
PMID: 35730384 Journal: AIDS Year: 2022 Reference: AIDS. 2022 Aug 1;36(10):1373-1382. doi: 10.1097/QAD.0000000000003276. Epub 2022 Jun 22. Impact factor: Publication type: Paper in international publication Authors: Ardanuy, Carmen; Bestard, Oriol; Calatayud, Laura; Cidraque, Ignacio; Crespo, Elena; Donadeu, Laura; Fava, Alexandre; Jouve, Thomas; Lozano, Juan J; Meneghini, Maria et al. DOI: 10.1097/QAD.0000000000003276
PMID: 34088718 Journal: Clinical Journal of the American Society of Nephrology Year: 2021 Reference: Clin J Am Soc Nephrol. 2021 Jul;16(7):1061-1072. doi: 10.2215/CJN.18961220. Epub 2021 Jun 4. Impact factor: Publication type: Paper in international publication Authors: Abramowicz, Daniel; Basile, Carlo; Covic, Adrian; Crespo, Marta; de Arriba, Gabriel; Duivenvoorden, Raphael; Gansevoort, Ronald; Massy, Ziad; Noordzij, Marlies; Ortiz, Alberto et al. DOI: 10.2215/CJN.18961220
PMID: 34098555 Journal: KIDNEY & BLOOD PRESSURE RESEARCH Year: 2021 Reference: Kidney Blood Press Res. 2021;46(4):452-459. doi: 10.1159/000515714. Epub 2021 Jun 7. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Baldallo, Cinthia; Bury, Roxana; Gabaldon, Alejandra; Garcia-Carro, Clara; Roman, Juan Leon; Seron, Daniel; Soler, Maria Jose; Toapanta, Nestor; Torres, Irina et al. DOI: 10.1159/000515714
PMID: 34069888 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 May 18;10(10). pii: jcm10102174. doi: 10.3390/jcm10102174. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Gabaldon, Maria-Alejandra; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Moreso, Francesc; Puig-Gay, Natalia; Sellares, Joana; Seron, Daniel; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.3390/jcm10102174
PMID: 34072230 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 May 27;10(11). pii: jcm10112364. doi: 10.3390/jcm10112364. Impact factor: Publication type: Review in international publication Authors: Ariton, Diana Maria; Delgado, Pilar; Jimenez-Balado, Joan; Maisterra, Olga; Pujadas, Francesc; Soler, Maria Jose et al. DOI: 10.3390/jcm10112364
PMID: 32118794 Journal: MEDICINE Year: 2020 Reference: Medicine (Baltimore). 2020 Feb;99(9):e19407. doi: 10.1097/MD.0000000000019407. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Lopez, Patricia; Berastegui, Cristina; Buti, Maria; Castells, Lluis; Esteban, Rafael; Flores-Cortes, Claudia; Oleas-Vega, Diana; Perello, Manel; Riveiro-Barciela, Mar; Roman, Antonio et al. DOI: 10.1097/MD.0000000000019407
PMID: 32112085 Journal: JOURNAL OF INFECTIOUS DISEASES Year: 2020 Reference: J Infect Dis. 2020 Jul 6;222(3):479-487. doi: 10.1093/infdis/jiaa090. Impact factor: Publication type: Paper in international publication Authors: Aguado, Jose Maria; Albert, Eliseo; Andres, Amado; Azancot, Maria Antonieta; Azancot, Maria Antonieta; Escudero-Sanchez, Rosa; Fernandez-Ruiz, Mario; Fortun, Jesus; Gimenez, Estela; Len, Oscar et al. DOI: 10.1093/infdis/jiaa090
PMID: 32085620 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2020 Reference: Int J Mol Sci. 2020 Feb 18;21(4). pii: ijms21041372. doi: 10.3390/ijms21041372. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Cortes-Hernandez, Josefina; Garcia-Vives, Eloi; Moline, Teresa; Ordi-Ros, Josep; Sole, Cristina; Vidal, Marta et al. DOI: 10.3390/ijms21041372
PMID: 32076718 Journal: CLINICAL INFECTIOUS DISEASES Year: 2020 Reference: Clin Infect Dis. 2020 Dec 3;71(9):2375-2385. doi: 10.1093/cid/ciz1209. Impact factor: Publication type: Paper in international publication Authors: Bestard, Oriol; Crespo, Elena; Cruzado, Josep M; Facundo, Carme; Gil Vernet, Salvador; Grinyo, Josep M; Guirado, Lluis; Gutierrez, Alex; Jarque, Marta; Manonelles, Anna et al. DOI: 10.1093/cid/ciz1209
PMID: 31197325 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2019 Reference: Nephrol Dial Transplant. 2019 Sep 1;34(9):1469-1480. doi: 10.1093/ndt/gfz089. Impact factor: 4.198 Publication type: Paper in international publication Authors: Sever, Mehmet Sukru, Massy, Ziad A, Caskey, Fergus J, Finne, Patrik, Harambat, Jerome, Jager, Kitty J, Nagler, Evi, Stengel, Benedicte, Bruchfeld, Annette, Capasso, Giovambattista et al. DOI: 10.1093/ndt/gfz089
PMID: 31198226 Journal: Clinical Kidney Journal Year: 2019 Reference: Clin Kidney J. 2019 Mar 6;12(3):322-325. doi: 10.1093/ckj/sfz019. eCollection 2019 Jun. Impact factor: 2.975 Publication type: Paper in international publication Authors: Vergara, Ander, Jacobs-Cacha, Conxita, Soler, Maria Jose et al. DOI: 10.1093/ckj/sfz019
PMID: 30497696 Journal: NEFROLOGIA Year: 2019 Reference: Nefrologia. 2019 Mar - Apr;39(2):151-159. doi: 10.1016/j.nefro.2018.07.013. Epub 2018 Nov 27. Impact factor: 1.439 Publication type: Paper in national publication Authors: Ramos, Ana, Pascual, Julio, Gavela, Eva, Jimenez, Carlos, Fernandez-Garcia, Anton, Perez Flores, Isabel, Portoles, Jose M, Perez-Saez, Maria Jose, Lopez-Sanchez, Paula, Lafuente-Covarrubias, Omar et al. DOI: 10.1016/j.nefro.2018.07.013
PMID: 30815678 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2019 Reference: Nephrol Dial Transplant. 2019 Jul 1;34(7):1112-1114. doi: 10.1093/ndt/gfz023. Impact factor: 4.198 Publication type: Paper in international publication Authors: Goumenos, Dimitrios, Ketteler, Markus, Massy, Ziad, Rychlik, Ivan, Soler, Maria, Stevens, Kate, Spasovski, Goce, Wanner, Christoph, Fouque, Denis, Fliser, Danilo et al. DOI: 10.1093/ndt/gfz023
PMID: 28328734 Journal: TRANSPLANTATION Year: 2017 Reference: Transplantation. 2017 Apr;101(4S Suppl 2):S1-S56. doi: 10.1097/TP.0000000000001651. Impact factor: 3.678 Publication type: Paper in international publication Authors: Rodriguez-Peralvarez, Manuel L, Samuel, Didier, Schneeberger, Stefan, Seron, Daniel, Trunecka, Pavel, Tisone, Giuseppe, van Gelder, Teun, Pirenne, Jacques, Nevens, Frederik, Kramer, Bernhard K et al. DOI: 10.1097/TP.0000000000001651
PMID: 28207630 Journal: TRANSPLANTATION Year: 2017 Reference: Transplantation. 2017 Jul;101(7):1527-1534. doi: 10.1097/TP.0000000000001648. Impact factor: 3.678 Publication type: Review in international publication Authors: Woodle, E Steve, Kuypers, Dirk, Mannon, Roslyn R, Abecassis, Michael, Chadban, Stephen, Gill, John S, Murphy, Barbara, Nickerson, Peter W, Schold, Jesse D, Stock, Peter et al. DOI: 10.1097/TP.0000000000001648
PMID: 27425627 Journal: Revista de calidad asistencial : organo de la Soci Year: 2017 Reference: Rev Calid Asist. 2017 Jan - Feb;32(1):33-39. doi: 10.1016/j.cali.2016.05.004. Epub 2016 Jul 15. Impact factor: 0 Publication type: Paper in national publication Authors: Costa-Requena, G, Cantarell, M C, Moreso, F, Parramon, G, Seron, D et al. DOI: 10.1016/j.cali.2016.05.004
PMID: 27862883 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2017 Reference: Am J Transplant. 2017 Jan;17(1):28-41. doi: 10.1111/ajt.14107. Impact factor: 6.165 Publication type: Editorail in international publication Authors: Alachkar, N, Bagnasco, S, Becker, J U, Cornell, L, Drachenberg, C, Dragun, D, de Kort, H, Gibson, I W, Kraus, E S, Lefaucheur, C et al. DOI: 10.1111/ajt.14107
PMID: 25103874 Journal: CLIN TRANSPLANT Year: 2014 Reference: Clin Transplant. 2014 Oct;28(10):1148-54. doi: 10.1111/ctr.12433. Epub 2014 Sep 11. Impact factor: 1.486 Publication type: Paper in international publication Authors: Torres, Irina B, Salcedo, Maite, Moreso, Francesc, Sellares, Joana, Castella, Eva, Azancot, M Antonieta, Perello, Manel, Cantarell, Carme, Seron, Daniel et al. DOI: 10.1111/ctr.12433
PMID: 25073029 Journal: TRANSPL IMMUNOL Year: 2014 Reference: Transpl Immunol. 2014 Sep;31(3):152-6. doi: 10.1016/j.trim.2014.07.001. Epub 2014 Jul 26. Impact factor: 1.832 Publication type: Paper in international publication Authors: Ibernon, M, Moreso, F, O'Valle, F, Grinyo, J M, Moral, R G, Seron, D et al. DOI: 10.1016/j.trim.2014.07.001
PMID: 25060591 Journal: GASTROENT HEPAT-BARC Year: 2014 Reference: Gastroenterol Hepatol. 2014 Oct;37(8):480-91. doi: 10.1016/j.gastrohep.2013.11.006. Epub 2014 Jul 22. Impact factor: 0.832 Publication type: Paper in national publication Authors: Castells, Lluis, Baliellas, Carme, Bilbao, Itxarone, Cantarell, Carme, Cruzado, Josep Maria, Esforzado, Nuria, Garcia-Valdecasas, Juan Carlos, Llado, Laura, Seron, Daniel, Oppenheimer, Federico et al. DOI: 10.1016/j.gastrohep.2013.11.006
PMID: 24712330 Journal: AM J TRANSPLANT Year: 2014 Reference: Am J Transplant. 2014 Apr;14(4):897-907. doi: 10.1111/ajt.12641. Epub 2014 Feb 20. Impact factor: 6.19 Publication type: Paper in international publication Authors: Mengel, M, Farris, A B, Chan, S, Climenhaga, J, Adam, B, Bellamy, C O C, Seron, D, Colvin, R B, Reeve, J et al. DOI: 10.1111/ajt.12641
PMID: 22293933 Journal: NEFROLOGIA Year: 2012 Reference: Nefrologia. 2012;32 Suppl 1:1-35. doi: 10.3265/Nefrologia.pre2011.Dec.11298. Impact factor: 1 Publication type: Paper in national publication Authors: Espinosa, Gerard, Ruiz Irastorza, Guillermo, Praga, Manuel, Pallares, Lucio, Rivera, Francisco, Robles Marhuenda, Angel, Segarra, Alfons, Quereda, Carlos, Jimenez Alonso, Juan, Frutos, Miguel A et al. DOI: 10.3265/Nefrologia.pre2011.Dec.11298
PMID: 22350120 Journal: Archives of sexual behavior Year: 2012 Reference: Arch Sex Behav. 2012 Aug;41(4):1059-63. doi: 10.1007/s10508-011-9894-2. Epub 2012 Feb 14. Impact factor: Publication type: Letter or abstract Authors: , , , , , , et al. DOI: 10.1007/s10508-011-9894-2
PMID: 22094957 Journal: TRANSPLANTATION Year: 2012 Reference: Transplantation. 2012 Jan 15;93(1):41-6. Impact factor: 4.003 Publication type: Paper in international publication Authors: , , , , , , , et al. DOI: 10.1097/TP.0b013e31823bb647
PMID: 22137728 Journal: Transplantation reviews (Orlando, Fla.) Year: 2012 Reference: Transplant Rev (Orlando). 2012 Jan;26(1):20-6. Impact factor: Publication type: Letter or abstract Authors: Seron, Daniel, Burgos, Dolores, Alonso, Angel et al. DOI: 10.1016/j.trre.2011.07.009
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.