Skip to main content

Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Podocytopathy in patients with monoclonal gammopathy: three patients and literature review.

PMID: 35211301
Journal: Clinical Kidney Journal
Year: 2022
Reference: Clin Kidney J. 2021 Sep 28;15(3):417-424. doi: 10.1093/ckj/sfab176. eCollection 2022 Mar.
Impact factor: 4.452
Publication type: Review in international publication
Authors: Crespo, Marta, Rodriguez, Eva, Gabaldon, Alejandra, Soler, Maria Jose, Lop, Joan, Ribas, Andres, Puche, Adrian, Gimeno, Javier, Sans, Laia, Barrios, Clara et al.
DOI: 10.1093/ckj/sfab176

Safety and Effectiveness of Isavuconazole Treatment for Fungal Infections in Solid Organ Transplant Recipients (ISASOT Study).

PMID: 35171022
Journal: Microbiology Spectrum
Year: 2022
Reference: Microbiol Spectr. 2022 Feb 23;10(1):e0178421. doi: 10.1128/spectrum.01784-21. Epub 2022 Feb 16.
Impact factor: 7.171
Publication type: Paper in international publication
Authors: Monforte, Arnau, Los-Arcos, Ibai, Martin-Gomez, Maria Teresa, Campany-Herrero, David, Sacanell, Judith, Berastegui, Cristina, Marquez-Algaba, Ester, Sempere, Abiu, Nuvials, Xavier, Castells, Lluis et al.
DOI: 10.1128/spectrum.01784-21

Antioxidant Roles of SGLT2 Inhibitors in the Kidney.

PMID: 35053290
Journal: Biomolecules
Year: 2022
Reference: Biomolecules. 2022 Jan 16;12(1). pii: biom12010143. doi: 10.3390/biom12010143.
Impact factor: 4.879
Publication type: Review in international publication
Authors: Llorens-Cebria, Carmen, Molina-Van den Bosch, Mireia, Vergara, Ander, Jacobs-Cacha, Conxita, Soler, Maria Jose et al.
DOI: 10.3390/biom12010143

The COVID-19 pandemic: progress in nephrology.

PMID: 34873314
Journal: Nature Reviews Nephrology
Year: 2022
Reference: Nat Rev Nephrol. 2022 Feb;18(2):80-81. doi: 10.1038/s41581-021-00521-4.
Impact factor: 28.314
Publication type: Review in international publication
Authors: Soler, Maria Jose, Jacobs-Cacha, Conxita et al.
DOI: 10.1038/s41581-021-00521-4

Secondary antibody deficiency is associated with development of infection in kidney transplantation: results of a multicenter study.

PMID: 33064917
Journal: Transplant Infectious Disease
Year: 2021
Reference: Transpl Infect Dis. 2021 Apr;23(2):e13494. doi: 10.1111/tid.13494. Epub 2020 Oct 27.
Impact factor: 2.228
Publication type: Paper in international publication
Authors: Anaya, Fernando, Lopez-Hoyos, Marcos, Rodrigo, Emilio, Arias, Manuel, Perello, Manel, Seron, Daniel, Karanovic, Boris, Ezzahouri, Ikram, Mezzano, Sergio, Jaramillo, Maria et al.
DOI: 10.1111/tid.13494

Focal and segmental glomerulosclerosis associated with COVID-19 infection.

PMID: 33888348
Journal: NEFROLOGIA
Year: 2021
Reference: Nefrologia (Engl Ed). 2021 Apr 19. pii: S0211-6995(21)00058-8. doi: 10.1016/j.nefro.2021.03.002.
Impact factor: 2.033
Publication type: Letter or abstract
Authors: LeonRoman, Juan, Vergara, Ander, Agraz, Irene, Garcia-Carro, Clara, Bermejo, Sheila, Gabaldon, Alejandra, Soler, Maria Jose et al.
DOI: 10.1016/j.nefro.2021.03.002

Surgeon preimplantation macroscopic graft appraisal improves risk stratification of deceased kidney donors: a prospective study.

PMID: 33887895
Journal: Minerva urology and nephrology
Year: 2021
Reference: Minerva Urol Nephrol. 2021 Apr 22. pii: S2724-6051.21.04345-7. doi: 10.23736/S2724-6051.21.04345-7.
Impact factor: 0
Publication type: Paper in international publication
Authors: Miret, Enric, Moreso, Francesc, Toapanta, Nestor, Lorente, David, Triquell, Marina, Pont, Teresa, Perez-Hoyos, Santiago, Seron, Daniel, Morote, Juan, Trilla, Enrique et al.
DOI: 10.23736/S2724-6051.21.04345-7

EFFECT OF RAMIPRIL ON KIDNEY, LUNG AND HEART ACE2 IN A DIABETIC MICE MODEL.

PMID: 33811970
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2021
Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111263. doi: 10.1016/j.mce.2021.111263. Epub 2021 Mar 31.
Impact factor: 4.102
Publication type: Paper in international publication
Authors: Soler, Maria Jose, Seron, Daniel, Garcia-Carro, Clara, Vergara, Ander, Jacobs-Cacha, Conxita, Molina-Van den Bosch, Mireia, Dominguez-Baez, Pamela, Benito, Begona et al.
DOI: 10.1016/j.mce.2021.111263

Efficacy and safety of bortezomib in refractory lupus nephritis: a single-center experience.

PMID: 31865857
Journal: LUPUS
Year: 2020
Reference: Lupus. 2020 Feb;29(2):118-125. doi: 10.1177/0961203319896018. Epub 2019 Dec 22.
Impact factor: 2.251
Publication type: Paper in international publication
Authors: Segarra, A, Arredondo, K V, Jaramillo, J, Jatem, E, Salcedo, M T, Agraz, I, Ramos, N, Carnicer, C, Valtierra, N, Ostos, E et al.
DOI: 10.1177/0961203319896018

A misprocessed form of Apolipoprotein A-I is specifically associated with recurrent Focal Segmental Glomerulosclerosis.

PMID: 31980684
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Jan 24;10(1):1159. doi: 10.1038/s41598-020-58197-y.
Impact factor: 3.998
Publication type: Paper in international publication
Authors: Jacobs-Cacha, Conxita, Puig-Gay, Natalia, Helm, Dominic, Rettel, Mandy, Sellares, Joana, Meseguer, Anna, Savitski, Mikhail M, Moreso, Francesc J, Soler, Maria Jose, Seron, Daniel et al.
DOI: 10.1038/s41598-020-58197-y

Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: the 2019 Expert Consensus From the Transplant Society Working Group.

PMID: 31895348
Journal: TRANSPLANTATION
Year: 2020
Reference: Transplantation. 2020 May;104(5):911-922. doi: 10.1097/TP.0000000000003095.
Impact factor: 4.264
Publication type: Paper in international publication
Authors: Tullius, Stefan G, Schinstock, Carrie A, Mannon, Roslyn B, Budde, Klemens, Chong, Anita S, Haas, Mark, Knechtle, Stuart, Lefaucheur, Carmen, Montgomery, Robert A, Nickerson, Peter et al.
DOI: 10.1097/TP.0000000000003095

MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade.

PMID: 31913319
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Jan 8;10(1):26. doi: 10.1038/s41598-019-56856-3.
Impact factor: 3.998
Publication type: Paper in international publication
Authors: Garcia-Fernandez, Nuria, Mora-Gutierrez, Jose Maria, Rodriguez, Jose Antonio, Fernandez-Seara, Maria A, Orbe, Josune, Escalada, Francisco Javier, Soler, Maria Jose, Slon Roblero, Maria Fernanda, Riera, Marta, Paramo, Jose Antonio et al.
DOI: 10.1038/s41598-019-56856-3

Blog

News

An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.

Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.

This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.

Job offers

Predoctoral Student
Start date:
23/09/2021
End date:
07/10/2021
Document: Download
Laboratory Technician - Nephrology Research Group.
Start date:
27/05/2021
End date:
10/06/2021
Document: Download
Data Entry /Manager Monitoring
Start date:
21/05/2021
End date:
04/06/2021
Document: Download