About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 37745119 Journal: Frontiers in Cardiovascular Medicine Year: 2023 Reference: Front Cardiovasc Med. 2023 Aug 25;10:1242108. doi: 10.3389/fcvm.2023.1242108. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Amiguet, Martina; Amiguet, Martina; Bayes-Genis, Antonio; Bodi, Vicent; Cabeza, Alejandro I Perez; Carmona, Jose David Martinez; Civera, Jose; Climent, Herminio Morillas; Conesa, Adriana; de la Espriella, Rafael et al. DOI: 10.3389/fcvm.2023.1242108
PMID: 37779839 Journal: Clinical Kidney Journal Year: 2023 Reference: Clin Kidney J. 2023 Jul 6;16(10):1656-1663. doi: 10.1093/ckj/sfad142. eCollection 2023 Oct. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Agraz, Irene; Barros, Xoana; Bermejo, Sheila; Bestard, Oriol; Bonet, Josep; Calero, Francesca; Coloma, Ana; Diaz, Montserrat; Diaz, Montserrat et al. DOI: 10.1093/ckj/sfad142
PMID: 37795587 Journal: KIDNEY INTERNATIONAL Year: 2023 Reference: Kidney Int. 2023 Sep 6:S0085-2538(23)00490-8. doi: 10.1016/j.kint.2023.06.032. Impact factor: Publication type: Paper in international publication Authors: Alexander, Mariam P; Amer, Hatem; Appel, Gerald B; Barbour, Sean J; Beck, Laurence H Jr; Caravaca-Fontan, Fernando; Casal Moura, Marta; Cattran, Daniel C; Caza, Tiffany N; D'Agati, Vivette D et al. DOI: 10.1016/j.kint.2023.06.032
PMID: 37804268 Journal: MAYO CLINIC PROCEEDINGS Year: 2023 Reference: Mayo Clin Proc. 2023 Sep 29:S0025-6196(23)00372-5. doi: 10.1016/j.mayocp.2023.08.006. Impact factor: Publication type: Paper in international publication Authors: Alexander, Mariam P; Amer, Hatem; Appel, Gerald B; Barbour, Sean J; Beck, Laurence H Jr; Caravaca-Fontan, Fernando; Casal Moura, Marta; Cattran, Daniel C; Caza, Tiffany N; D'Agati, Vivette D et al. DOI: 10.1016/j.mayocp.2023.08.006
PMID: 35844497 Journal: Frontiers in Immunology Year: 2022 Reference: Front Immunol. 2022 Jun 29;13:902837. doi: 10.3389/fimmu.2022.902837. eCollection 2022. Impact factor: Publication type: Paper in international publication Authors: Alvarez, Antonio; Alvarez, Antonio; Alvarez-Sierra, Daniel; Anton, Andres; Arrese-Munoz, Iria; Bas-Minguet, Jordi; Blanco-Grau, Albert; Blanco-Grau, Albert; Bosch-Nicolau, Pau; Buzon, Maria Jose et al. DOI: 10.3389/fimmu.2022.902837
PMID: 35833145 Journal: Frontiers in Immunology Year: 2022 Reference: Front Immunol. 2022 Jun 27;13:869554. doi: 10.3389/fimmu.2022.869554. eCollection 2022. Impact factor: Publication type: Paper in international publication Authors: Bemelman, Frederike; Bestard, Oriol; Crespo, Elena; Cruzado, Josep M; Donadeu, Laura; Fava, Alex; Fontova, Pere; Goma, Montserrat; Grinyo, Josep; Hruba, Petra et al. DOI: 10.3389/fimmu.2022.869554
PMID: 35806939 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 Jun 24;11(13). pii: jcm11133651. doi: 10.3390/jcm11133651. Impact factor: Publication type: Letter or abstract Authors: Alia-Ramos, Pedro; Bestard, Oriol; Codina, Sergi; Cruzado, Josep M; De Carvalho Ovalles, Rosa Alejandra; Donadeu, Laura; Fava, Alexandre; Fernandez-Cidon, Barbara; Goma, Montserrat; Gomez Preciado, Francisco et al. DOI: 10.3390/jcm11133651
PMID: 35775000 Journal: Frontiers in Medicine Year: 2022 Reference: Front Med (Lausanne). 2022 Jun 14;9:906565. doi: 10.3389/fmed.2022.906565. eCollection 2022. Impact factor: Publication type: Review in international publication Authors: Bermejo, Sheila; Bolufer, Monica; Riveiro-Barciela, Mar; Soler, Maria Jose et al. DOI: 10.3389/fmed.2022.906565
PMID: 34221369 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 Feb 10;14(5):1364-1370. doi: 10.1093/ckj/sfaa008. eCollection 2021 May. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Bolufer, Monica; Bury, Roxana; Espinel, Eugenia; Felip, Enriqueta; Gabaldon, Alejandra; Garcia-Carro, Clara; Munoz, Eva; Oleas, Diana; Seron, Daniel et al. DOI: 10.1093/ckj/sfaa008
PMID: 34198818 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Jun 5;10(11). pii: jcm10112505. doi: 10.3390/jcm10112505. Impact factor: Publication type: Review in international publication Authors: Agraz, Irene; Azancot, Maria A; Azancot, Maria A; Bermejo, Sheila; Garcia-Carro, Clara; Sanchez de la Nieta, M Dolores; Sanchez-Fructuoso, Ana I; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.3390/jcm10112505
PMID: 34174006 Journal: Transplant Infectious Disease Year: 2021 Reference: Transpl Infect Dis. 2021 Aug;23(4):e13677. doi: 10.1111/tid.13677. Epub 2021 Jul 12. Impact factor: Publication type: Letter or abstract Authors: Berastegui, Cristina; Castells, Lluis; Garcia-Garcia, Sonia; Gorgas Torner, Maria Q; Larrosa-Garcia, Maria; Los-Arcos, Ibai; Miarons, Marta; Moreso, Francesc et al. DOI: 10.1111/tid.13677
PMID: 33359528 Journal: KIDNEY INTERNATIONAL Year: 2021 Reference: Kidney Int. 2021 Jul;100(1):196-205. doi: 10.1016/j.kint.2020.12.015. Epub 2020 Dec 24. Impact factor: Publication type: Paper in international publication Authors: Abdel-Wahab, Noha; Abdelrahim, Maen; Abudayyeh, Ala; Alhamad, Tarek; Bassil, Claude; Blosser, Christopher; Cardarelli, Francesca; Danesh, Melissa; Danovitch, Gabriel M; Devoe, Craig E et al. DOI: 10.1016/j.kint.2020.12.015
PMID: 31815310 Journal: CLINICAL TRANSPLANTATION Year: 2020 Reference: Clin Transplant. 2020 Jan;34(1):e13767. doi: 10.1111/ctr.13767. Epub 2019 Dec 31. Impact factor: Publication type: Paper in international publication Authors: Aladren, Maria Jose; Andres, Amado; Beneyto, Isabel; Calvino, Jesus; Cigarran, Secundino; Diekmann, Fritz; Franco, Antonio; Gomez, Gonzalo; Gonzalez Posada, Jose Manuel; Lauzurica, Ricardo et al. DOI: 10.1111/ctr.13767
PMID: 31598700 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Feb 1;35(2):222-226. doi: 10.1093/ndt/gfz199. Impact factor: Publication type: Paper in international publication Authors: Blankestijn, Peter J; Bruchfeld, Annette; Capasso, Giovambattista; Fliser, Danilo; Fouque, Denis; Goumenos, Dimitrios; Massy, Ziad; Rychlik, Ivan; Soler, Maria J; Spasovski, Goce et al. DOI: 10.1093/ndt/gfz199
PMID: 31203229 Journal: JOURNAL OF RHEUMATOLOGY Year: 2020 Reference: J Rheumatol. 2020 Mar;47(3):407-414. doi: 10.3899/jrheum.190065. Epub 2019 Jun 15. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Garcia-Vives, Eloi; Martinez-Valle, Ferran; Segarra-Medrano, Alfons; Solans-Laque, Roser et al. DOI: 10.3899/jrheum.190065
PMID: 31071220 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Jan 1;35(1):10-17. doi: 10.1093/ndt/gfz051. Impact factor: Publication type: Editorail in international publication Authors: Blankestijn, Peter J; Bruchfeld, Annette; Capasso, Giovambattista; Eckardt, Kai-Uwe; Fliser, Danilo; Fouque, Denis; Frische, Sebastian; Gesualdo, Loreto; Goumenos, Dimitrios; Gutierrez, Eugenio et al. DOI: 10.1093/ndt/gfz051
PMID: 31242927 Journal: BMC Nephrology Year: 2019 Reference: BMC Nephrol. 2019 Jun 26;20(1):233. doi: 10.1186/s12882-019-1412-0. Impact factor: 2.088 Publication type: Paper in international publication Authors: Llamas, Francisco, Lopez-Sanchez, Paula, Sanchez-Sobrino, Beatriz, Perez-Saez, Maria Jose, Santos, Julio Pascual, Zapatero, Ana, Hernandez-Marrero, Domingo, Moreso, Francesc, Melilli, Edoardo, Manonelles, Anna et al. DOI: 10.1186/s12882-019-1412-0
PMID: 31214630 Journal: Open Forum Infectious Diseases Year: 2019 Reference: Open Forum Infect Dis. 2019 May 21;6(6):ofz243. doi: 10.1093/ofid/ofz243. eCollection 2019 Jun. Impact factor: 3.371 Publication type: Paper in international publication Authors: Cruzado, Josep M, Carratala, Jordi, Moreso, Francesc, Len, Oscar, Riera, Lluis, Sabe, Nuria, Oriol, Isabel, Melilli, Edoardo, Manonelles, Anna, Bestard, Oriol et al. DOI: 10.1093/ofid/ofz243
PMID: 31212945 Journal: Journal of Clinical Medicine Year: 2019 Reference: J Clin Med. 2019 Jun 17;8(6). pii: jcm8060864. doi: 10.3390/jcm8060864. Impact factor: 5.688 Publication type: Review in international publication Authors: Soler, Maria Jose, Seron, Daniel, Espinel, Eugenia, Jacobs-Cacha, Conxita, Garcia-Carro, Clara, Vergara, Ander, Agraz, Irene et al. DOI: 10.3390/jcm8060864
PMID: 31198532 Journal: Clinical Kidney Journal Year: 2019 Reference: Clin Kidney J. 2019 May 31;12(3):313-321. doi: 10.1093/ckj/sfz070. eCollection 2019 Jun. Impact factor: 2.975 Publication type: Paper in international publication Authors: Fernandez-Fernandez, Beatriz, Fernandez-Prado, Raul, Gorriz, Jose Luis, Martinez-Castelao, Alberto, Navarro-Gonzalez, Juan F, Porrini, Esteban, Soler, Maria Jose, Ortiz, Alberto et al. DOI: 10.1093/ckj/sfz070
PMID: 29380890 Journal: CLINICAL TRANSPLANTATION Year: 2018 Reference: Clin Transplant. 2018 Mar;32(3):e13196. doi: 10.1111/ctr.13196. Epub 2018 Jan 30. Impact factor: 1.518 Publication type: Paper in international publication Authors: Garcia-Carro, Clara, Dorje, Christina, Midtvedt, Karsten, Scott, Helge, Reinholt, Finn P, Holdaas, Hallvard, Reisaeter, Anna V, Seron, Daniel, Asberg, Anders et al. DOI: 10.1111/ctr.13196
PMID: 29340322 Journal: Kidney international reports Year: 2018 Reference: Kidney Int Rep. 2017 Sep 28;3(1):122-132. doi: 10.1016/j.ekir.2017.08.016. eCollection 2018 Jan. Impact factor: 0 Publication type: Paper in international publication Authors: Cruzado, Josep M, Lauzurica, Ricardo, Pascual, Julio, Marcen, Roberto, Moreso, Francesc, Gutierrez-Dalmau, Alex, Andres, Amado, Hernandez, Domingo, Torres, Armando, Beneyto, Maria Isabel et al. DOI: 10.1016/j.ekir.2017.08.016
PMID: 28811074 Journal: Transplantation Reviews Year: 2018 Reference: Transplant Rev (Orlando). 2018 Jan;32(1):36-57. doi: 10.1016/j.trre.2017.07.001. Epub 2017 Jul 26. Impact factor: 2.364 Publication type: Clinical guide Authors: Martin-Davila, P, Montejo, M, Moreno, A, Oliver, A, Pascual, A, Perez-Nadales, E, Roman-Broto, A, San-Juan, R, Seron, D, Sole-Jover, A et al. DOI: 10.1016/j.trre.2017.07.001
PMID: 28495395 Journal: NEFROLOGIA Year: 2017 Reference: Nefrologia. 2017 May - Jun;37(3):320-329. doi: 10.1016/j.nefro.2016.11.019. Epub 2017 May 8. Impact factor: 1.183 Publication type: Paper in national publication Authors: Segarra-Medrano, Alfons, Carnicer-Caceres, Clara, Agraz-Pamplona, Irene, Ramos-Terrades, Natalia, Jatem Escalante, Elias, Ostos-Roldan, Elena, Valtierra-Carmeno, Naiara et al. DOI: 10.1016/j.nefro.2016.11.019
PMID: 28449409 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2017 Reference: Am J Transplant. 2017 Nov;17(11):2851-2862. doi: 10.1111/ajt.14329. Epub 2017 May 30. Impact factor: 6.165 Publication type: Paper in international publication Authors: Halloran, Philip F, Reeve, Jeff, Akalin, Enver, Aubert, Olivier, Bohmig, Georg A, Brennan, Daniel, Bromberg, Jonathan, Einecke, Gunilla, Gosset, Clement, Duong Van Huyen, Jean-Paul et al. DOI: 10.1111/ajt.14329
PMID: 28427723 Journal: MEDICINA CLINICA Year: 2017 Reference: Med Clin (Barc). 2017 Aug 10;149(3):114-118. doi: 10.1016/j.medcli.2017.02.032. Epub 2017 Apr 17. Impact factor: 1.125 Publication type: Paper in national publication Authors: Seron, Daniel, Costa-Requena, Gema, Cantarell, M Carmen, Moreso, Francesc, Parramon, Gemma et al. DOI: 10.1016/j.medcli.2017.02.032
PMID: 28429866 Journal: Transplant Infectious Disease Year: 2017 Reference: Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12711. Epub 2017 Jun 9. Impact factor: 1.719 Publication type: Paper in international publication Authors: Sandiumenge, Alberto, Martinez-Saez, Elena, Pumarola, Tomas, Bodro, Marta, Macias, Antonio, Silva, Jose T, Nuvials, F Xavier, Charco, Ramon, Moreso, Francesc, Pont, Teresa et al. DOI: 10.1111/tid.12711
PMID: 25061126 Journal: NEPHROL DIAL TRANSPL Year: 2014 Reference: Nephrol Dial Transplant. 2014 Oct;29(10):1956-64. doi: 10.1093/ndt/gfu253. Epub 2014 Jul 24. Impact factor: 3.488 Publication type: Paper in international publication Authors: Vanholder, Raymond, Noordzij, Marlies, Jager, Kitty J, van der Veer, Sabine N, Kramar, Reinhard, Collart, Frederic, Heaf, James G, Stojceva-Taneva, Olivera, Leivestad, Torbjorn, Buturovic-Ponikvar, Jadranka et al. DOI: 10.1093/ndt/gfu253
PMID: 25118611 Journal: INT J PEPT RES THER Year: 2014 Reference: Int Urol Nephrol. 2014 Oct;46(10):1983-95. doi: 10.1007/s11255-014-0800-4. Epub 2014 Aug 14. Impact factor: 1.293 Publication type: Paper in international publication Authors: Portoles, Jose, Calls, Jordi, Martinez-Castelao, Alberto, Munar, Maria Antonia, Segarra, Alfonso, Cases, Aleix et al. DOI: 10.1007/s11255-014-0800-4
PMID: 25096639 Journal: AM J NEPHROL Year: 2014 Reference: Am J Nephrol. 2014;40(2):105-12. doi: 10.1159/000365256. Epub 2014 Jul 30. Impact factor: 2.646 Publication type: Paper in international publication Authors: Rivera, Francisco, Merida, Evangelina, Illescas, Maria L, Lopez-Rubio, E, Frutos, Miguel A, Garcia-Frias, Patricia, Ramos, Carmela, Sierra, Maria, Baltar, Jose, Lucas, Jesus et al. DOI: 10.1159/000365256
PMID: 25278376 Journal: AM J TRANSPLANT Year: 2014 Reference: Am J Transplant. 2014 Dec;14(12):2796-806. doi: 10.1111/ajt.12955. Epub 2014 Oct 2. Impact factor: 6.19 Publication type: Clinical Trials Authors: El-Ghoroury, Mohamed A, Goldstein, Michael J, Gaston, Robert S, Gohh, Reginald Y, Killackey, Mary T, King, Anne, Knight, Richard J, Kore, Arputharaj H, Sudan, Debra L, Chapochnick Friedmann, Javier et al. DOI: 10.1111/ajt.12955
PMID: 22717945 Journal: NEFROLOGIA Year: 2012 Reference: Nefrologia. 2012;32 Suppl 2:1-28. doi: 10.3265/Nefrologia.pre2012.Mar.11433. Impact factor: 1 Publication type: Paper in national publication Authors: Guirado, Lluis, del Cerro, Luis Antonio Jimenez, Bautista, Luis Gonzalo, Pallardo, Luis, Artamendi, Marta, Crespo, Marta, Bennouna, Mazine, Munoz, Miguel Angel, Ridao, Natalia, Inigo, Pablo et al. DOI: 10.3265/Nefrologia.pre2012.Mar.11433
PMID: 22361331 Journal: REVISTA CLINICA ESPANOLA Year: 2012 Reference: Rev Clin Esp. 2012 Mar;212(3):147.e1-30. Epub 2012 Feb 22. Impact factor: 2.008 Publication type: Paper in national publication Authors: Quereda, C, Ruiz-Irastorza, G, Espinosa, G, Frutos, M A, Jimenez Alonso, J, Praga, M, Pallares, L, Rivera, F, Robles Marhuenda, A, Segarra, A et al. DOI: 10.1016/j.rce.2012.01.001
PMID: 22015441 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2012 Reference: Nephrol Dial Transplant. 2012 May;27(5):2089-95. Epub 2011 Oct 19. Impact factor: 3.396 Publication type: Paper in international publication Authors: , , , , , , , et al. DOI: 10.1093/ndt/gfr587
PMID: 22137725 Journal: Transplantation reviews Year: 2012 Reference: Transplant Rev (Orlando). 2012 Jan;26(1):1-2. Impact factor: Publication type: Letter or abstract Authors: Seron, Daniel et al. DOI: 10.1016/j.trre.2011.10.005
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.
