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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Publications

Association of renin-angiotensin system blockers with COVID-19 diagnosis and prognosis in patients with hypertension: a population-based study.

PMID: 35035939
Journal: Clinical Kidney Journal
Year: 2022
Reference: Clin Kidney J. 2021 Sep 3;15(1):79-94. doi: 10.1093/ckj/sfab161. eCollection 2022 Jan.
Impact factor: 4.452
Publication type: Paper in international publication
Authors: Soler, Maria Jose, Ribera, Aida, Marsal, Josep R, Mendez, Ana Belen, Andres, Mireia, Azancot, Maria Antonia, Oristrell, Gerard, Mendez-Boo, Leonardo, Cohen, Jordana, Barrabes, Jose A et al.
DOI: 10.1093/ckj/sfab161

Loss of humoral response 3 months after SARS-CoV-2 vaccination in the CKD spectrum: the multicentric SENCOVAC study.

PMID: 35022757
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2022
Reference: Nephrol Dial Transplant. 2022 Apr 25;37(5):994-999. doi: 10.1093/ndt/gfac007.
Impact factor: 5.992
Publication type: Paper in international publication
Authors: Carmona, Nicolas Macias, Ortiz, Alberto, Bernat, Amparo, Diaz, Ana Beatriz Munoz, Mantecon, Carlos Jesus Jarava, Perez, Virginia Olinda Gomez, Gonzalez, Carmen Calderon, Cervienka, Michal, Mazuecos, Auxiliadora, Cazorla, Juan Manuel et al.
DOI: 10.1093/ndt/gfac007

Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells.

PMID: 35025963
Journal: PLoS Pathogens
Year: 2022
Reference: PLoS Pathog. 2022 Jan 13;18(1):e1010171. doi: 10.1371/journal.ppat.1010171. eCollection 2022 Jan.
Impact factor: 6.823
Publication type: Paper in international publication
Authors: Grau-Exposito, Judith, Perea, David, Suppi, Marina, Massana, Nuria, Vergara, Ander, Soler, Maria Jose, Trinite, Benjamin, Blanco, Julia, Garcia-Perez, Javier, Alcami, Jose et al.
DOI: 10.1371/journal.ppat.1010171

Revisiting the Renin-Angiotensin System.

PMID: 33819521
Journal: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Year: 2021
Reference: Mol Cell Endocrinol. 2021 Jun 1;529:111268. doi: 10.1016/j.mce.2021.111268. Epub 2021 Apr 2.
Impact factor: 4.102
Publication type: Editorail in international publication
Authors: Soler, Maria Jose, Batlle, Daniel et al.
DOI: 10.1016/j.mce.2021.111268

Kidney transplantation and COVID-19 renal and patient prognosis.

PMID: 33815780
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 26;14(Suppl 1):i21-i29. doi: 10.1093/ckj/sfab030. eCollection 2021 Mar.
Impact factor: 4.452
Publication type: Review in international publication
Authors: Toapanta, Nestor, Torres, Irina B, Sellares, Joana, Chamoun, Betty, Seron, Daniel, Moreso, Francesc et al.
DOI: 10.1093/ckj/sfab030

COVID-19 and its impact on the kidney and the nephrology community.

PMID: 33815779
Journal: Clinical Kidney Journal
Year: 2021
Reference: Clin Kidney J. 2021 Mar 26;14(Suppl 1):i1-i5. doi: 10.1093/ckj/sfab039. eCollection 2021 Mar.
Impact factor: 4.452
Publication type: Editorail in international publication
Authors: Soler, Maria Jose, Batlle, Daniel et al.
DOI: 10.1093/ckj/sfab039

Active bleeding after kidney biopsy: Successful ultrasound-guided direct thrombin embolization into the cortical fistula.

PMID: 33098132
Journal: JOURNAL OF CLINICAL ULTRASOUND
Year: 2021
Reference: J Clin Ultrasound. 2021 May;49(4):390-394. doi: 10.1002/jcu.22939. Epub 2020 Oct 24.
Impact factor: 0.91
Publication type: Letter or abstract
Authors: Escudero-Fernandez, Jose Miguel, Bolufer Cardona, Monica, Perez Lafuente, Mercedes, Montealegre, Carolina, Uriarte, Iciar, Serres-Creixams, Xavier et al.
DOI: 10.1002/jcu.22939

Blog

News

A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.

An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.

Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.