About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
PMID: 38012160 Journal: Nature Communications Year: 2023 Reference: Nat Commun. 2023 Nov 27;14(1):7770. doi: 10.1038/s41467-023-43652-x. Impact factor: Publication type: Paper in international publication Authors: Alonso, Fabiola; Arpa, Berta; Aunon, Pilar; Corral-Pujol, Marta; Cosovanu, Catalina; Egia-Mendikute, Leire; Garcia, Patricia; Garcia-Carro, Clara; Gutierrez, Eduardo; Manichanh, Chaysavanh et al. DOI: 10.1038/s41467-023-43652-x
PMID: 38020746 Journal: TRANSPLANT INTERNATIONAL Year: 2023 Reference: Transpl Int. 2023 Nov 7;36:11963. doi: 10.3389/ti.2023.11963. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Bestard, Oriol; Couzi, Lionel; Del Carmen, Amin; Fernandez-Ruiz, Mario; Garnacho-Castano, Manuel V; Kaminski, Hannah; Manuel, Oriol; Miravitlles, Marc; Moreno, Eva; Pleguezuelos, Eulogio et al. DOI: 10.3389/ti.2023.11963
PMID: 38025231 Journal: Kidney International Reports Year: 2023 Reference: Kidney Int Rep. 2023 Sep 20;8(11):2492. doi: 10.1016/j.ekir.2023.08.011. eCollection 2023 Nov. Impact factor: Publication type: Paper in international publication Authors: Aguasca, Gerard Marti; Alujas, Teresa Gonzalez; Barcelo, Maria Calvo; Barrabes, Jose A; Belahnech, Yassin; Bellera, Neus; Calabuig, Alvaro; Fernandez-Galera, Ruben; Galian-Gay, Laura; Garcia Del Blanco, Bruno et al. DOI: 10.1016/j.ekir.2023.08.011
PMID: 38032448 Journal: JOURNAL OF CLINICAL MONITORING AND COMPUTING Year: 2023 Reference: J Clin Monit Comput. 2023 Nov 30. doi: 10.1007/s10877-023-01110-5. Impact factor: Publication type: Paper in international publication Authors: Corbett, Matthew; Gonzalez-Suarez, Susana; Hernandez-Martinez, Alberto; Lopez-Martinez, Marina; Machado, Miriam; Rico-Fontalvo, Jorge; Soler, Maria Jose et al. DOI: 10.1007/s10877-023-01110-5
PMID: 35669972 Journal: TRANSPLANT INTERNATIONAL Year: 2022 Reference: Transpl Int. 2022 May 20;35:10138. doi: 10.3389/ti.2022.10138. eCollection 2022. Impact factor: Publication type: Editorail in international publication Authors: Bellini, Maria Irene; Bestard, Oriol; Bohmig, Georg A; Budde, Klemens; Claas, Frans; Couzi, Lionel; Furian, Lucrezia; Heemann, Uwe; Mamode, Nizam; Naesens, Maarten et al. DOI: 10.3389/ti.2022.10138
PMID: 35669978 Journal: TRANSPLANT INTERNATIONAL Year: 2022 Reference: Transpl Int. 2022 May 20;35:10141. doi: 10.3389/ti.2022.10141. eCollection 2022. Impact factor: Publication type: Editorail in international publication Authors: Becker, Jan Ulrich; Naesens, Maarten; Rabant, Marion; Roufosse, Candice; Seron, Daniel et al. DOI: 10.3389/ti.2022.10141
PMID: 35669975 Journal: TRANSPLANT INTERNATIONAL Year: 2022 Reference: Transpl Int. 2022 May 20;35:10135. doi: 10.3389/ti.2022.10135. eCollection 2022. Impact factor: Publication type: Review in international publication Authors: Becker, Jan Ulrich; Bellini, Maria Irene; Bohmig, Georg A; Budde, Klemens; Diekmann, Fritz; Glotz, Denis; Hilbrands, Luuk; Loupy, Alexandre; Naesens, Maarten; Oberbauer, Rainer et al. DOI: 10.3389/ti.2022.10135
PMID: 35669973 Journal: TRANSPLANT INTERNATIONAL Year: 2022 Reference: Transpl Int. 2022 May 20;35:10140. doi: 10.3389/ti.2022.10140. eCollection 2022. Impact factor: Publication type: Editorail in international publication Authors: Becker, Jan Ulrich; Bellini, Maria Irene; Bohmig, Georg A; Budde, Klemens; Diekmann, Fritz; Glotz, Denis; Hilbrands, Luuk; Loupy, Alexandre; Naesens, Maarten; Oberbauer, Rainer et al. DOI: 10.3389/ti.2022.10140
PMID: 33340043 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2021 Reference: Nephrol Dial Transplant. 2021 Jan 1;36(1):87-94. doi: 10.1093/ndt/gfaa314. Impact factor: Publication type: Paper in international publication Authors: Cozzolino, Mario; Duivenvoorden, Raphael; Fliser, Danilo; Fouque, Denis; Franssen, Casper F M; Gansevoort, Ron T; Gansevoort, Ron T; Goumenos, Dimitrios; Hemmelder, Marc H; Hilbrands, Luuk B et al. DOI: 10.1093/ndt/gfaa314
PMID: 33986388 Journal: Scientific Reports Year: 2021 Reference: Sci Rep. 2021 May 13;11(1):10171. doi: 10.1038/s41598-021-89562-0. Impact factor: Publication type: Paper in international publication Authors: Bello, Irene; Berastegui, Cristina; Bravo, Carlos; Burgos, Rosa; Escobar, Roser; Ferrandiz-Pulido, Carla; Gomez, Alba; Gomez-Olles, Susana; Lopez-Meseguer, Manuel; Mendez, Alejandra et al. DOI: 10.1038/s41598-021-89562-0
PMID: 33098200 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2021 Reference: Am J Transplant. 2021 May;21(5):1825-1837. doi: 10.1111/ajt.16369. Epub 2020 Nov 10. Impact factor: Publication type: Paper in international publication Authors: Aguado, Beatriz; Bada-Bosch, Teresa; Bravo, Carlos; Burgos, Elena; Cabello, Mercedes; Coll, Elisabeth; Crespo, Marta; de Pablo, Alicia; Dominguez-Gil, Beatriz; Facundo, Carme et al. DOI: 10.1111/ajt.16369
PMID: 32810390 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2021 Reference: Am J Transplant. 2021 May;21(5):1683-1684. doi: 10.1111/ajt.16272. Epub 2020 Sep 9. Impact factor: Publication type: Editorail in international publication Authors: Cruzado, Josep M; Montero, Nuria; Moreso, Francesc et al. DOI: 10.1111/ajt.16272
PMID: 31865540 Journal: INTERNATIONAL JOURNAL OF HEMATOLOGY Year: 2020 Reference: Int J Hematol. 2020 Mar;111(3):440-450. doi: 10.1007/s12185-019-02796-7. Epub 2019 Dec 21. Impact factor: Publication type: Paper in international publication Authors: Alsina, Laia; Catala, Albert; Colobran, Roger; de la Campa, Elena Alvarez; de la Cruz, Xavier; Donadeu, Laura; Esteve-Sole, Ana; Martinez-Gallo, Monica; Rincon, Rafael; Sayos, Joan et al. DOI: 10.1007/s12185-019-02796-7
PMID: 32046355 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Feb 8;9(2). pii: jcm9020472. doi: 10.3390/jcm9020472. Impact factor: Publication type: Review in international publication Authors: Garcia-Fernandez, Nuria; Jacobs-Cacha, Conxita; Mora-Gutierrez, Jose Maria; Orbe, Josune; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.3390/jcm9020472
PMID: 31869590 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2020 Reference: J Neurol Sci. 2020 Feb 15;409:116635. doi: 10.1016/j.jns.2019.116635. Epub 2019 Dec 14. Impact factor: Publication type: Paper in international publication Authors: Delgado, Pilar; Espinel, Eugenia; Jimenez-Balado, Joan; Maisterra, Olga; Palasi, Antoni; Penalba, Anna; Pizarro, Jesus; Pujadas, Francesc; Ramirez, Clara; Ramos, Natalia et al. DOI: 10.1016/j.jns.2019.116635
PMID: 32003834 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Jan 1;35(Supplement_1):i13-i23. doi: 10.1093/ndt/gfz237. Impact factor: Publication type: Paper in international publication Authors: Gorriz, Jose Luis; Jacobs-Cacha, Conxita; Martinez-Castelao, Alberto; Navarro-Gonzalez, Juan F; Nunez, Julio; Ortiz, Alberto; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.1093/ndt/gfz237
PMID: 30773693 Journal: TRANSPLANT INTERNATIONAL Year: 2019 Reference: Transpl Int. 2019 Jul;32(7):710-716. doi: 10.1111/tri.13410. Epub 2019 Mar 10. Impact factor: 3.526 Publication type: Paper in international publication Authors: Franco, A, Moreso, F, Merino, E, Sancho, A, Kanter, J, Gimeno, A, Balibrea, N, Perez Contreras, J, Rodriguez, M et al. DOI: 10.1111/tri.13410
PMID: 30760090 Journal: LUPUS Year: 2019 Reference: Lupus. 2019 Mar;28(3):396-405. doi: 10.1177/0961203319828521. Epub 2019 Feb 13. Impact factor: 2.924 Publication type: Paper in international publication Authors: Garcia-Vives, E, Sole, C, Moline, T, Alvarez-Rios, A M, Vidal, M, Agraz, I, Ordi-Ros, J, Cortes-Hernandez, J et al. DOI: 10.1177/0961203319828521
PMID: 30747149 Journal: Clinical Kidney Journal Year: 2019 Reference: Clin Kidney J. 2019 Feb;12(1):33-35. doi: 10.1093/ckj/sfy079. Epub 2018 Oct 3. Impact factor: 2.975 Publication type: Paper in international publication Authors: Diaz, Montserrat, Agraz, Irene, Soler, Maria Jose et al. DOI: 10.1093/ckj/sfy079
PMID: 30411406 Journal: TRANSPLANT INTERNATIONAL Year: 2019 Reference: Transpl Int. 2019 Mar;32(3):313-322. doi: 10.1111/tri.13372. Epub 2018 Nov 28. Impact factor: 3.526 Publication type: Paper in international publication Authors: Puig-Gay, Natalia, Jacobs-Cacha, Conxita, Sellares, Joana, Guirado, Lluis, Gonzalez Roncero, Francisco, Jimenez, Carlos, Zarraga, Sofia, Paul, Javier, Lauzurica, Ricardo, Angel, Alonso et al. DOI: 10.1111/tri.13372
PMID: 28125449 Journal: TRANSPLANTATION Year: 2017 Reference: Transplantation. 2017 Feb;101 Suppl 2S:S1-S41. doi: 10.1097/TP.0000000000001563. Impact factor: 3.678 Publication type: Editorail in international publication Authors: Grinyo, Josep, Loupy, Alexandre, Kuypers, Dirk, Mariat, Christophe, Clancy, Marc, Jardine, Alan G, Guirado, Lluis, Fellstrom, Bengt, O'Grady, John, Pirenne, Jacques et al. DOI: 10.1097/TP.0000000000001563
PMID: 24810779 Journal: TRANSPL IMMUNOL Year: 2014 Reference: Transpl Immunol. 2014 Jun;31(1):11-6. doi: 10.1016/j.trim.2014.04.008. Epub 2014 May 5. Impact factor: 1.832 Publication type: Paper in international publication Authors: Moreso, Francesc, Martinez-Gallo, Monica, Benlloch, Susana, Cantarell, Carme, Perello, Manel, Jimeno, Jose, Pujol-Borrell, Ricardo, Seron, Daniel, Torres, Irina B et al. DOI: 10.1016/j.trim.2014.04.008
PMID: 24770618 Journal: TRANSPLANTATION Year: 2014 Reference: Transplantation. 2014 Sep 15;98(5):537-42. doi: 10.1097/TP.0000000000000103. Impact factor: 3.535 Publication type: Paper in international publication Authors: Azancot, Maria A, Ramos, Natalia, Moreso, Francesc J, Ibernon, Meritxell, Espinel, Eugenia, Torres, Irina B, Fort, Joan, Seron, Daniel et al. DOI: 10.1097/TP.0000000000000103
PMID: 25259815 Journal: NEFROLOGIA Year: 2014 Reference: Nefrologia. 2014 Sep 26;34(5):605-10. doi: 10.3265/Nefrologia.pre2014.Jun.11881. Impact factor: 1.442 Publication type: Paper in national publication Authors: Costa-Requena, Gemma, Cantarell-Aixendri, M Carmen, Parramon-Puig, Gemma, Seron-Micas, Daniel et al. DOI: 10.3265/Nefrologia.pre2014.Jun.11881
PMID: 25068388 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Jul 28;9(7):e103028. doi: 10.1371/journal.pone.0103028. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Riveiro-Barciela, Mar, Buti, Maria, Homs, Maria, Campos-Varela, Isabel, Cantarell, Carmen, Crespo, Manuel, Castells, Lluis, Tabernero, David, Quer, Josep, Esteban, Rafael et al. DOI: 10.1371/journal.pone.0103028
The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.
Hypertension, a key risk factor for heart disease that contributes significantly to cardiovascular mortality and morbidity and damage to vital organs, was the focus of this multi-centre study.
The new findings were presented at the American Society of Nephrology's Kidney Week 2024 meeting in San Diego and simultaneously published in the prestigious journal Nature Medicine.