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Neurovascular Diseases

Stroke is a medical emergency and a leading cause of death and disability worldwide affecting millions of subjects. In this context the Neurovascular Research Laboratory was created in 2001 focused in stroke research from a basic and translational perspective, covering all stages of the disease: from prevention and treatment, to recovery.

Nowadays our team is composed by a highly motivated group of researchers including clinical and basic scientists, with group leaders involved in National and International projects with public or private research funding on biomarkers for clinical decision making in stroke, the presence of silent infarctions, the assessment of cognition and cognitive decline, developing experimental models of cerebral ischemia testing new treatments complementary to reperfusion, and developing studies on cerebral amyloid angiopathy, tissue neurorepair or post-stroke rehabilitation.

Complementary studies on vascular dementia and Alzheimer disease related to amyloid-beta protein have also been encompassed as part of our research in the last years.

Publications

Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management.

PMID: 33619704
Journal: DRUGS & AGING
Year: 2021
Reference: Drugs Aging. 2021 Apr;38(4):285-299. doi: 10.1007/s40266-021-00837-7. Epub 2021 Feb 23.
Impact factor: 3.923
Publication type: Review in international publication
Authors: Galovic, Marian, Ferreira-Atuesta, Carolina, Abraira, Laura, Dohler, Nico, Sinka, Lucia, Brigo, Francesco, Bentes, Carla, Zelano, Johan, Koepp, Matthias J et al.
DOI: 10.1007/s40266-021-00837-7

Incidence and mortality in adults with epilepsy in northern Spain.

PMID: 32969054
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2021
Reference: Acta Neurol Scand. 2021 Jan;143(1):27-33. doi: 10.1111/ane.13349. Epub 2020 Oct 13.
Impact factor: 3.209
Publication type: Paper in international publication
Authors: Quintana, Manuel, Sanchez-Lopez, Javier, Mazuela, Gonzalo, Santamarina, Estevo, Abraira, Laura, Fonseca, Elena, Seijo, Ivan, Alvarez-Sabin, Jose, Toledo, Manuel et al.
DOI: 10.1111/ane.13349

Corrigendum to 'Screening of Embolic Sources by Point-of-Care Ultrasound in the Acute Phase of Ischemic Stroke' [Ultrasound in Med. & Biol. 46 (2020) 2173-2180].

PMID: 33589352
Journal: ULTRASOUND IN MEDICINE AND BIOLOGY
Year: 2021
Reference: Ultrasound Med Biol. 2021 May;47(5):1428. doi: 10.1016/j.ultrasmedbio.2021.01.021. Epub 2021 Feb 12.
Impact factor: 2.998
Publication type: Letter or abstract
Authors: Juega, Jesus, Pagola, Jorge, Gonzalez-Alujas, Teresa, Rodriguez-Luna, David, Rubiera, Marta, Rodriguez-Villatoro, Noelia, Garcia-Tornel, Alvaro, Requena, Manuel, Deck, Matias, Sero, Laia et al.
DOI: 10.1016/j.ultrasmedbio.2021.01.021

Blood Biomarkers to Predict Long-Term Mortality after Ischemic Stroke.

PMID: 33578805
Journal: Life-Basel
Year: 2021
Reference: Life (Basel). 2021 Feb 10;11(2). pii: life11020135. doi: 10.3390/life11020135.
Impact factor: 3.817
Publication type: Paper in international publication
Authors: Ramiro, Laura, Abraira, Laura, Quintana, Manuel, Garcia-Rodriguez, Paula, Santamarina, Estevo, Alvarez-Sabin, Jose, Zaragoza, Josep, Hernandez-Perez, Maria, Ustrell, Xavier, Lara, Blanca et al.
DOI: 10.3390/life11020135

Vascular risk factors as independent predictors of neurocognitive impairments in patients with late-onset epilepsy who have small-vessel disease.

PMID: 31399342
Journal: EPILEPSY & BEHAVIOR
Year: 2020
Reference: Epilepsy Behav. 2020 Mar;104(Pt B):106443. doi: 10.1016/j.yebeh.2019.106443. Epub 2019 Aug 6.
Impact factor: 2.508
Publication type: Paper in international publication
Authors: Turon, Marc, Abraira, Laura, Cazorla, Sonia, Fonseca, Elena, Quintana, Manuel, Toledo, Manuel, Salas-Puig, Xavier, Santamarina, Estevo et al.
DOI: 10.1016/j.yebeh.2019.106443

Corrigendum to "Correlation of blood biomarkers with early-onset seizures after an acute stroke event" [Epilepsy Behav 104(Pt B) (2020 Mar)].

PMID: 32248061
Journal: EPILEPSY & BEHAVIOR
Year: 2020
Reference: Epilepsy Behav. 2020 May;106:107045. doi: 10.1016/j.yebeh.2020.107045. Epub 2020 Apr 2.
Impact factor: 2.508
Publication type: Letter or abstract
Authors: Montaner, Joan, Alvarez-Sabin, Jose, Davalos, Antoni, Castellanos, Mar, Ustrell, Xavier, Abraira, Laura, Giannini, Nicola, Santamarina, Estevo, Cazorla, Sonia, Bustamante, Alejandro et al.
DOI: 10.1016/j.yebeh.2020.107045

Proteasomal-mediated degradation of AKAP150 accompanies AMPAR endocytosis during cLTD.

PMID: 32205379
Journal: eNeuro
Year: 2020
Reference: eNeuro. 2020 Apr 16;7(2). pii: ENEURO.0218-19.2020. doi: 10.1523/ENEURO.0218-19.2020. Print 2020 Mar/Apr.
Impact factor: 3.544
Publication type: Paper in international publication
Authors: Cheng, Wenwen, Siedlecki-Wullich, Dolores, Catala-Solsona, Judit, Fabregas, Cristina, Fado, Rut, Sole, Montse, Unzeta, Mercedes, Saura, Carlos A, Rodriguez-Alvarez, Jose, Minano-Molina, Alfredo J et al.
DOI: 10.1523/ENEURO.0218-19.2020

Correlation of blood biomarkers with early-onset seizures after an acute stroke event.

PMID: 31677998
Journal: EPILEPSY & BEHAVIOR
Year: 2020
Reference: Epilepsy Behav. 2020 Mar;104(Pt B):106549. doi: 10.1016/j.yebeh.2019.106549. Epub 2019 Oct 31.
Impact factor: 2.508
Publication type: Paper in international publication
Authors: Grau-Lopez, Laia, Jimenez, Marta, Ciurans, Jordi, Becerra, Juan Luis, Millan, Monica, Cardona, Pere, Terceno, Mikel, Zaragoza, Josep, Canovas, David, Gasull, Teresa et al.
DOI: 10.1016/j.yebeh.2019.106549

Cognitive Impact of Cerebral Small Vessel Disease Changes in Patients With Hypertension.

PMID: 30606062
Journal: HYPERTENSION
Year: 2019
Reference: Hypertension. 2019 Feb;73(2):342-349. doi: 10.1161/HYPERTENSIONAHA.118.12090.
Impact factor: 7.017
Publication type: Paper in international publication
Authors: Delgado, Pilar, Ventura, Oriol, Jimenez-Balado, Joan, Riba-Llena, Iolanda, Abril, Oscar, Garde, Edurne, Penalba, Anna, Ostos, Elena, Maisterra, Olga, Montaner, Joan et al.
DOI: 10.1161/HYPERTENSIONAHA.118.12090

Blog

News

For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.

The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.

The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.