About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
PMID: 39735510 Journal: Network Neuroscience Year: 2024 Reference: Netw Neurosci. 2024 Dec 10;8(4):1545-1562. doi: 10.1162/netn_a_00404. eCollection 2024. Impact factor: Publication type: Paper in international publication Authors: Collorone, Sara; Deco, Gustavo; Filippi, Massimo; Foster, Michael A; Gonzalez-Escamilla, Gabriel; Groppa, Sergiu; Harbo, Hanne F; Hogestol, Einar A; Llufriu, Sara; Marti-Juan, Gerard et al. DOI: 10.1162/netn_a_00404
PMID: 38101890 Journal: LANCET NEUROLOGY Year: 2024 Reference: Lancet Neurol. 2024 Jan;23(1):22-24. doi: 10.1016/S1474-4422(23)00459-3. Impact factor: Publication type: Paper in international publication Authors: Tintore, Mar; Tur, Carmen et al. DOI: 10.1016/S1474-4422(23)00459-3
PMID: 38165383 Journal: NEUROLOGY Year: 2024 Reference: Neurology. 2024 Jan 9;102(1):e207936. doi: 10.1212/WNL.0000000000207936. Epub 2023 Dec 13. Impact factor: Publication type: Editorail in international publication Authors: Rocca, Maria A; Tur, Carmen et al. DOI: 10.1212/WNL.0000000000207936
PMID: 38165378 Journal: NEUROLOGY Year: 2024 Reference: Neurology. 2024 Jan 9;102(1):e200805. doi: 10.1212/WNL.0000000000207805. Epub 2023 Dec 13. Impact factor: Publication type: Paper in international publication Authors: Arrambide, Georgina; Auger, Cristina; Bisecco, Alvino; Calderon, Willem; Capuano, Rocco; Castillo, Joaquin; Cerda-Fuertes, Nuria; Ciccarelli, Olga; Collorone, Sara; De Barros, Andrea et al. DOI: 10.1212/WNL.0000000000207805
PMID: 37183562 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2023 Reference: Eur J Neurol. 2023 May 14. doi: 10.1111/ene.15866. Impact factor: Publication type: Paper in international publication Authors: Chuquisana, Omar; Comabella, Manuel; Ferrer, Roser; Fissolo, Nicolas; Gil-Varea, Elia; Giralt, Marina; Lunemann, Jan D; Malhotra, Sunny; Midaglia, Luciana; Montalban, Xavier et al. DOI: 10.1111/ene.15866
PMID: 37089424 Journal: Frontiers in Physiology Year: 2023 Reference: Front Physiol. 2023 Apr 6;14:1145818. doi: 10.3389/fphys.2023.1145818. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Bailon, Raquel; Buron, Mathias Due; Comi, Giancarlo; Costa, Gloria Dalla; Cummins, Nicholas; Dobson, Richard J B; Folarin, Amos A; Garcia, Esther; Guerrero, Ana Isabel; Hotopf, Matthew et al. DOI: 10.3389/fphys.2023.1145818
PMID: 37086636 Journal: Multiple Sclerosis and Related Disorders Year: 2023 Reference: Mult Scler Relat Disord. 2023 Apr 17;74:104724. doi: 10.1016/j.msard.2023.104724. Impact factor: Publication type: Paper in international publication Authors: Aldevert, Mireia; Anglada, Elisenda; Arevalo, Maria Jesus; Bascunana, Helena; Curto, Gemma; Feliu, Patricia; Galan, Ingrid; Garcia, Itziar; Garcia, Montserrat; Gonzalo, Lorena et al. DOI: 10.1016/j.msard.2023.104724
PMID: 37816633 Journal: NEUROLOGY Year: 2023 Reference: Neurology. 2023 Oct 10:10.1212/WNL.0000000000207957. doi: 10.1212/WNL.0000000000207957. Impact factor: Publication type: Paper in international publication Authors: Aguayo-Ortiz, Rafael; Akgun, Katja; Arrambide, Georgina; Bassas-Freixas, Patricia; Bassas-Freixas, Patricia; Bermel, Robert A; Bernia-Petit, Eduardo; Bonfill-Orti, Montserrat; Calabresi, Peter A; Canueto, Javier et al. DOI: 10.1212/WNL.0000000000207957
PMID: 35088080 Journal: HUMAN MOLECULAR GENETICS Year: 2022 Reference: Hum Mol Genet. 2022 Jul 7;31(13):2155-2163. doi: 10.1093/hmg/ddac009. Impact factor: Publication type: Paper in international publication Authors: Alcina, Antonio; Andres-Leon, Eduardo; Barroso-Del-Jesus, Alicia; Comabella, Manuel; Eichau, Sara; Fedetz, Maria; Garcia-Sanchez, Maria-Isabel; Gil-Varea, Elia; Izquierdo, Guillermo; Leyva, Laura et al. DOI: 10.1093/hmg/ddac009
PMID: 32856989 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Feb;28(2):173-182. doi: 10.1177/1352458520952022. Epub 2020 Aug 28. Impact factor: Publication type: Paper in international publication Authors: Baro, Francesc; Midaglia, Luciana; Montalban, Xavier; Otero, Susana; Tintore, Mar et al. DOI: 10.1177/1352458520952022
PMID: 35084734 Journal: REVISTA DE NEUROLOGIA Year: 2022 Reference: Rev Neurol. 2022 Feb 1;74(3):93-104. doi: 10.33588/rn.7403.2021473. Impact factor: Publication type: Review in national publication Authors: Moncho, D; Pareto, D; Rodriguez-Acevedo, B; Rovira, A; Sastre-Garriga, J; Vidal-Jordana, A et al. DOI: 10.33588/rn.7403.2021473
PMID: 34913743 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Feb;28(2):187-188. doi: 10.1177/13524585211049073. Epub 2021 Dec 16. Impact factor: Publication type: Letter or abstract Authors: Fox, Robert J; Tintore, Mar et al. DOI: 10.1177/13524585211049073
PMID: 33436375 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2021 Reference: Neurol Neuroimmunol Neuroinflamm. 2021 Jan 12;8(2). pii: 8/2/e941. doi: 10.1212/NXI.0000000000000941. Print 2021 Mar. Impact factor: Publication type: Paper in international publication Authors: Borras, Eva; Brito, Veronica; Comabella Lopez, Manuel; Costa, Carme; Dujmovic, Irena; Fissolo, Nicolas; Issazadeh-Navikas, Shohreh; Khalil, Michael; Matute-Blanch, Clara; Miro, Berta et al. DOI: 10.1212/NXI.0000000000000941
PMID: 33431183 Journal: MEDICINA CLINICA Year: 2021 Reference: Med Clin (Barc). 2021 May 21;156(10):509-514. doi: 10.1016/j.medcli.2020.10.015. Epub 2021 Jan 9. Impact factor: Publication type: Paper in national publication Authors: Bosch Ferrer, Montserrat; Filippi-Arriaga, Francesca; Riera-Arnau, Judit; Rodriguez-Acevedo, Breogan et al. DOI: 10.1016/j.medcli.2020.10.015
PMID: 31845614 Journal: Multiple Sclerosis Journal Year: 2021 Reference: Mult Scler. 2021 Jan;27(1):90-96. doi: 10.1177/1352458519895450. Epub 2019 Dec 17. Impact factor: Publication type: Paper in international publication Authors: Edan, Gilles; Galan, Ingrid; Kalkers, Nynke F; Kamm, Christian P; Kerbrat, Anne; McGuigan, Chris; Mokkink, Lidwine B; Montalban, Xavier; O'Connell, Karen; Tacchino, Andrea et al. DOI: 10.1177/1352458519895450
PMID: 33106392 Journal: NEUROLOGY Year: 2021 Reference: Neurology. 2021 Jan 5;96(1):12-13. doi: 10.1212/WNL.0000000000011120. Epub 2020 Oct 26. Impact factor: Publication type: Editorail in international publication Authors: Kalincik, Tomas; Sormani, Maria Pia; Tur, Carmen et al. DOI: 10.1212/WNL.0000000000011120
PMID: 32125223 Journal: Multiple Sclerosis Journal Year: 2020 Reference: Mult Scler. 2020 Apr;26(4):407-408. doi: 10.1177/1352458519895749. Epub 2020 Mar 3. Impact factor: Publication type: Paper in international publication Authors: Arrambide, Georgina et al. DOI: 10.1177/1352458519895749
PMID: 32110891 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Feb 26;9(3). pii: jcm9030625. doi: 10.3390/jcm9030625. Impact factor: Publication type: Paper in international publication Authors: Alcina, Antonio; Bosch, Elena; Castillo-Trivino, Tamara; Comabella, Manuel; Eixarch, Herena; Fedetz, Maria; Fernandez, Oscar; Gil-Varea, Elia; Izquierdo, Guillermo; Leyva, Laura et al. DOI: 10.3390/jcm9030625
PMID: 32094485 Journal: Nature Reviews Neurology Year: 2020 Reference: Nat Rev Neurol. 2020 Mar;16(3):171-182. doi: 10.1038/s41582-020-0314-x. Epub 2020 Feb 24. Impact factor: Publication type: Review in international publication Authors: Barkhof, Frederik; Battaglini, Marco; Ciccarelli, Olga; De Stefano, Nicola; Enzinger, Christian; Filippi, Massimo; Frederiksen, Jette; Gasperini, Claudio; Kappos, Ludwig; Montalban, Xavier et al. DOI: 10.1038/s41582-020-0314-x
PMID: 32057303 Journal: LANCET NEUROLOGY Year: 2020 Reference: Lancet Neurol. 2020 Mar;19(3):234-246. doi: 10.1016/S1474-4422(19)30488-0. Epub 2020 Feb 10. Impact factor: Publication type: Paper in international publication Authors: Aguilera-Albesa, Sergio; Alcantud, Alberto; Alvarez Demanuel, Diana; Alvarez Molinero, Mireia; Aquino Farina, Lourdes; Arino, Helena; Armangue, Thais; Arrabal, Luisa; Arrambide, Georgina; Arriola-Pereda, Gema et al. DOI: 10.1016/S1474-4422(19)30488-0
PMID: 31072248 Journal: INTERVENTIONAL NEURORADIOLOGY Year: 2019 Reference: Interv Neuroradiol. 2019 Oct;25(5):491-496. doi: 10.1177/1591019919847623. Epub 2019 May 9. Impact factor: 1.45 Publication type: Paper in international publication Authors: Tomasello, Alejandro, Ribo, Marc, Gramegna, Laura Ludovica, Melendez, Fernando, Rosati, Santiago, Moreu, Manuel, Aixut, Sonia, Luttich, Alexandre, Werner, Mariano, Remollo, Sebastian et al. DOI: 10.1177/1591019919847623
PMID: 30587516 Journal: NEUROLOGY Year: 2019 Reference: Neurology. 2019 Jan 22;92(4):180-192. doi: 10.1212/WNL.0000000000006810. Epub 2018 Dec 26. Impact factor: 8.689 Publication type: Review in international publication Authors: Gasperini, Claudio, Prosperini, Luca, Tintore, Mar, Sormani, Maria Pia, Filippi, Massimo, Rio, Jordi, Palace, Jacqueline, Rocca, Maria A, Ciccarelli, Olga, Barkhof, Frederik et al. DOI: 10.1212/WNL.0000000000006810
PMID: 30037730 Journal: Hipertension y riesgo vascular Year: 2019 Reference: Hipertens Riesgo Vasc. 2019 Apr - Jun;36(2):70-84. doi: 10.1016/j.hipert.2018.06.002. Epub 2018 Jul 20. Impact factor: 0 Publication type: Paper in national publication Authors: Sabate, N, Merino, M, Ferrer-Vidal, D, Gorriz, J L, Muniz, O, Galgo, A, Hidalgo-Vega, A, Martell, N, Orozco-Beltran, D et al. DOI: 10.1016/j.hipert.2018.06.002
PMID: 30880560 Journal: NEUROREHABILITATION AND NEURAL REPAIR Year: 2019 Reference: Neurorehabil Neural Repair. 2019 Apr;33(4):260-270. doi: 10.1177/1545968319834893. Epub 2019 Mar 17. Impact factor: 3.757 Publication type: Paper in international publication Authors: Knuts, Kathy, Kalron, Alon, Feys, Peter, Dalgas, Ulrik, Smedal, Tori, Freeman, Jennifer, Romberg, Anders, Conyers, Helen, Elorriaga, Iratxe, Gebara, Benoit et al. DOI: 10.1177/1545968319834893
PMID: 29326424 Journal: Nature Reviews Neurology Year: 2018 Reference: Nat Rev Neurol. 2018 Feb;14(2):75-93. doi: 10.1038/nrneurol.2017.171. Epub 2018 Jan 12. Impact factor: Publication type: Review in international publication Authors: Barkhof, Frederik; Chataway, Jeremy; Ciccarelli, Olga; Moccia, Marcello; Sastre-Garriga, Jaume; Thompson, Alan J; Tur, Carmen et al. DOI: 10.1038/nrneurol.2017.171
PMID: 29318919 Journal: Multiple Sclerosis Journal Year: 2018 Reference: Mult Scler. 2018 Apr;24(5):576-577. doi: 10.1177/1352458517751648. Epub 2018 Jan 10. Impact factor: Publication type: Review in international publication Authors: Sastre-Garriga, Jaume et al. DOI: 10.1177/1352458517751648
PMID: 29177546 Journal: JOURNAL OF NEUROLOGY Year: 2018 Reference: J Neurol. 2018 Jan;265(1):32. doi: 10.1007/s00415-017-8679-5. Impact factor: Publication type: Letter or abstract Authors: Alenda, Raquel; Alvarez-Cermeno, Jose C; Alvarez-Lafuente, Roberto; Costa-Frossard, Lucienne; Dominguez-Mozo, Maria I; Espejo, Carmen; Montalban, Xavier; Rio, Jordi; Rodriguez-Martin, Eulalia; Sainz de la Maza, Susana et al. DOI: 10.1007/s00415-017-8679-5
PMID: 29027004 Journal: JOURNAL OF NEUROLOGY Year: 2018 Reference: J Neurol. 2018 Jan;265(1):24-31. doi: 10.1007/s00415-017-8625-6. Epub 2017 Oct 12. Impact factor: Publication type: Paper in international publication Authors: Alenda, Raquel; Alvarez-Cermeno, Jose C; Alvarez-Lafuente, Roberto; Costa-Frossard, Lucienne; de la Maza, Susana Sainz; Dominguez-Mozo, Maria I; Espejo, Carmen; Montalban, Xavier; Rio, Jordi; Rodriguez-Martin, Eulalia et al. DOI: 10.1007/s00415-017-8625-6
PMID: 27306626 Journal: NEUROLOGY Year: 2016 Reference: Neurology. 2016 Jul 12;87(2):134-40. doi: 10.1212/WNL.0000000000002830. Epub 2016 Jun 15. Impact factor: 8.166 Publication type: Paper in international publication Authors: Prosperini, Luca, Rocca, Maria Assunta, Rovira, Alex, Sprenger, Till, Stromillo, Maria Laura, Tedeschi, Gioacchino, Tintore, Mar, Tortorella, Carla, Trojano, Maria, Montalban, Xavier et al. DOI: 10.1212/WNL.0000000000002830
PMID: 27282863 Journal: AMERICAN JOURNAL OF NEURORADIOLOGY Year: 2016 Reference: AJNR Am J Neuroradiol. 2016 Oct;37(10):1816-1823. doi: 10.3174/ajnr.A4829. Epub 2016 Jun 9. Impact factor: 3.124 Publication type: Paper in international publication Authors: Cabezas, M, Corral, J F, Oliver, A, Diez, Y, Tintore, M, Auger, C, Montalban, X, Llado, M, Pareto, D, Rovira, A et al. DOI: 10.3174/ajnr.A4829
PMID: 26810535 Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES Year: 2016 Reference: J Neurol Sci. 2016 Feb 15;361:158-67. doi: 10.1016/j.jns.2015.12.043. Epub 2015 Dec 29. Impact factor: 2.126 Publication type: Review in national publication Authors: Rio, Jordi, Ruiz-Pena, Juan Luis et al. DOI: 10.1016/j.jns.2015.12.043
PMID: 26935253 Journal: JOURNAL OF NEUROIMAGING Year: 2016 Reference: J Neuroimaging. 2016 Sep;26(5):532-8. doi: 10.1111/jon.12337. Epub 2016 Mar 2. Impact factor: 1.625 Publication type: Paper in international publication Authors: Rovira, Alex, Vidal-Jordana, Angela, Sastre-Garriga, Jaume, Perez-Miralles, Francisco, Pareto, Deborah, Rio, Jordi, Auger, Cristina, Tintore, Mar, Montalban, Xavier et al. DOI: 10.1111/jon.12337
PMID: 25698781 Journal: JOURNAL OF NUCLEAR MEDICINE Year: 2015 Reference: J Nucl Med. 2015 Apr;56(4):580-5. doi: 10.2967/jnumed.114.150383. Epub 2015 Feb 19. Impact factor: 6.16 Publication type: Paper in international publication Authors: Biegon, Anat, Alexoff, David L, Kim, Sung Won, Logan, Jean, Pareto, Deborah, Schlyer, David, Wang, Gene-Jack, Fowler, Joanna S et al. DOI: 10.2967/jnumed.114.150383
PMID: 25634715 Journal: AMERICAN JOURNAL OF NEURORADIOLOGY Year: 2015 Reference: AJNR Am J Neuroradiol. 2015 May;36(5):871-6. doi: 10.3174/ajnr.A4231. Epub 2015 Jan 29. Impact factor: 3.589 Publication type: Paper in international publication Authors: Alcaide-Leon, P, Pareto, D, Martinez-Saez, E, Auger, C, Bharatha, A, Rovira, A et al. DOI: 10.3174/ajnr.A4231
PMID: 26450537 Journal: AMERICAN JOURNAL OF NEURORADIOLOGY Year: 2015 Reference: AJNR Am J Neuroradiol. 2015 Dec;36(12):2270-6. doi: 10.3174/ajnr.A4485. Epub 2015 Oct 8. Impact factor: 3.589 Publication type: Paper in international publication Authors: Pareto, D, Sastre-Garriga, J, Auger, C, Vives-Gilabert, Y, Delgado, J, Tintore, M, Montalban, X, Rovira, A et al. DOI: 10.3174/ajnr.A4485
PMID: 26305477 Journal: Translational Psychiatry Year: 2015 Reference: Transl Psychiatry. 2015 Aug 25;5:e626. doi: 10.1038/tp.2015.122. Impact factor: 5.62 Publication type: Paper in international publication Authors: Batalla, A, Bargallo, N, Gasso, P, Molina, O, Pareto, D, Mas, S, Roca, J M, Bernardo, M, Lafuente, A, Parellada, E et al. DOI: 10.1038/tp.2015.122
PMID: 23250676 Journal: REVISTA DE NEUROLOGIA Year: 2013 Reference: Rev Neurol. 2013 Jan 1;56(1):8-12. Impact factor: 1.179 Publication type: Paper in national publication Authors: Lopez-Mendez, P, Rio, J, Perez-Ricart, A, Tintore, M, Sastre-Garriga, J, Cardona-Pascual, I, Gomez-Domingo, M R, Montalban, X et al. DOI:
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
