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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Team

Sergio Cabello

Sergio Cabello

Research technician
Clinical Neuroimmunology
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Silvia Ferrer López

Silvia Ferrer López

Administration and Management
Clinical Neuroimmunology
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Sergio Cabello

Sergio Cabello

Research technician
Clinical Neuroimmunology
Read more
Silvia Ferrer López

Silvia Ferrer López

Administration and Management
Clinical Neuroimmunology
Read more

Publications

Ocrelizumab in Early-Stage Relapsing-Remitting Multiple Sclerosis: The Phase IIIb ENSEMBLE 4-Year, Single-Arm, Open-Label Trial.

PMID: 39626127
Journal: NEUROLOGY
Year: 2024
Reference: Neurology. 2024 Dec 24;103(12):e210049. doi: 10.1212/WNL.0000000000210049. Epub 2024 Dec 3.
Impact factor:
Publication type: Paper in international publication
Authors: Benedict, Ralph H B; Berger, Thomas; Bermel, Robert A; Brochet, Bruno; Carroll, William M; Clinch, Susanne; Freedman, Mark S; Hartung, Hans-Peter; Holmoy, Trygve; Kadner, Karen et al.
DOI: 10.1212/WNL.0000000000210049

Chitinase 3-like 1 is neurotoxic in multiple sclerosis patient-derived cortical neurons.

PMID: 39658520
Journal: Clinical and Translational Medicine
Year: 2024
Reference: Clin Transl Med. 2024 Dec;14(12):e70125. doi: 10.1002/ctm2.70125.
Impact factor:
Publication type: Paper in international publication
Authors: Comabella, Manuel; Duarri, Anna; Eixarch, Herena; Lizcano, Jose M; Lopez Comellas, Gloria; Malhotra, Sunny; Matute-Blanch, Clara; Montalban, Xavier; Pinteac, Rucsanda; Soriano, Jordi et al.
DOI: 10.1002/ctm2.70125

Increased EBNA1-specific antibody response in primary-progressive multiple sclerosis.

PMID: 39666032
Journal: JOURNAL OF NEUROLOGY
Year: 2024
Reference: J Neurol. 2024 Dec 12;272(1):26. doi: 10.1007/s00415-024-12763-w.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelhak, Ahmed; Alvarez-Lafuente, Roberto; Bachhuber, Franziska; Behrens, Malina; Berek, Klaus; Blanco, Yolanda; Carbonell-Mirabent, Pere; Castillo-Trivino, Tamara; Comabella, Manuel; Fissolo, Nicolas et al.
DOI: 10.1007/s00415-024-12763-w

Prevalence of distance walking fatigability in multiple sclerosis according to MS phenotype, disability severity and walking speed.

PMID: 39657457
Journal: Annals of Physical and Rehabilitation Medicine
Year: 2024
Reference: Ann Phys Rehabil Med. 2024 Dec 9;68(1):101887. doi: 10.1016/j.rehab.2024.101887.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Abasiyanik, Zuhal; Dalgas, Ulrik; Feys, Peter; Gebara, Benoit; Leone, Carmela; Maamagi, Heigo; Ozakbas, Serkan; Ramari, Cintia; Rasova, Kamila; Romberg, Anders et al.
DOI: 10.1016/j.rehab.2024.101887

Safety and efficacy with alemtuzumab over 13 years in relapsing-remitting multiple sclerosis: final results from the open-label TOPAZ study.

PMID: 37745914
Journal: Therapeutic Advances in Neurological Disorders
Year: 2023
Reference: Ther Adv Neurol Disord. 2023 Sep 21;16:17562864231194823. doi: 10.1177/17562864231194823. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Achiron, Anat; Chirieac, Magdalena; Coles, Alasdair J; Comi, Giancarlo; Freedman, Mark S; Giovannoni, Gavin; Montalban, Xavier; Oreja-Guevara, Celia; Pozzilli, Carlo; Rawlings, Andreea M et al.
DOI: 10.1177/17562864231194823

Family Planning in Fertile-Age Patients With Multiple Sclerosis (MS) (ConPlanEM Study): Delphi Consensus Statements.

PMID: 37746391
Journal: Cureus
Year: 2023
Reference: Cureus. 2023 Aug 24;15(8):e44056. doi: 10.7759/cureus.44056. eCollection 2023 Aug.
Impact factor:
Publication type: Paper in international publication
Authors: Meca, Jose; Meca, Virginia; Mendibe, Mar; Oreja-Guevara, Celia; Prieto, Jose Maria; Rodriguez-Antiguedad, Alfredo; Rodriguez-Antiguedad, Alfredo; Tintore, Mar et al.
DOI: 10.7759/cureus.44056

Association of magnetic resonance imaging phenotypes and serum biomarker levels with treatment response and long-term disease outcomes in multiple sclerosis patients.

PMID: 37754568
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2023
Reference: Eur J Neurol. 2023 Sep 27. doi: 10.1111/ene.16077.
Impact factor:
Publication type: Paper in international publication
Authors: Castillo, Joaquin; Comabella, Manuel; Comabella, Manuel; Fissolo, Nicolas; Midaglia, Luciana; Miro, Berta; Montalban, Xavier; Rio, Jordi; Rio, Jordi; Rovira, Alex et al.
DOI: 10.1111/ene.16077

Assessing treatment response to oral drugs for multiple sclerosis in real-world setting: a MAGNIMS Study.

PMID: 37775266
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2023
Reference: J Neurol Neurosurg Psychiatry. 2023 Sep 29:jnnp-2023-331920. doi: 10.1136/jnnp-2023-331920.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Araji, Sarmad; Annovazzi, Pietro Osvaldo; Barkhof, Frederik; Bisecco, Alvino; Ciccarelli, Olga; Ciccarelli, Olga; De Stefano, Nicola; Enzinger, Christian; Enzinger, Christian; Evangelou, Nikos et al.
DOI: 10.1136/jnnp-2023-331920

Early and unrestricted access to high-efficacy disease-modifying therapies: a consensus to optimize benefits for people living with multiple sclerosis.

PMID: 34626224
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Mar;269(3):1670-1677. doi: 10.1007/s00415-021-10836-8. Epub 2021 Oct 9.
Impact factor:
Publication type: Paper in international publication
Authors: Danesi, Romano; Derfuss, Tobias; Duddy, Martin; Filippi, Massimo; Gallo, Paolo; Gold, Ralf; Havrdova, Eva Kubala; Kornek, Barbara; Sacca, Francesco; Tintore, Mar et al.
DOI: 10.1007/s00415-021-10836-8

Spatial patterns of brain lesions assessed through covariance estimations of lesional voxels in multiple Sclerosis: The SPACE-MS technique.

PMID: 34875458
Journal: NeuroImage-Clinical
Year: 2022
Reference: Neuroimage Clin. 2022;33:102904. doi: 10.1016/j.nicl.2021.102904. Epub 2021 Dec 2.
Impact factor:
Publication type: Paper in international publication
Authors: Calvi, Alberto; Charalambous, Thalis; Chard, Declan T; Chataway, Jeremy; Ciccarelli, Olga; Cortese, Rosa; De Angelis, Floriana; Eshaghi, Arman; Gandini Wheeler-Kingshott, Claudia A M; Grussu, Francesco et al.
DOI: 10.1016/j.nicl.2021.102904

Performance of Activities of daily living in people with multiple sclerosis.

PMID: 35158429
Journal: Multiple Sclerosis and Related Disorders
Year: 2022
Reference: Mult Scler Relat Disord. 2022 Jan;57:103342. doi: 10.1016/j.msard.2021.103342. Epub 2021 Oct 21.
Impact factor:
Publication type: Paper in international publication
Authors: Ferdinand, Sofie; Fillo, Nuria; Huilla, Tarja; Ilsbroukx, Stephan; Jakobson, Jytte; Jansa, Jelka; Kallmayer, Lene; Kos, Daphne; Loyning, Inger G; Milo, Meta et al.
DOI: 10.1016/j.msard.2021.103342

Effect of desire for pregnancy on decisions to escalate treatment in multiple sclerosis care: Differences between MS specialists and non-MS specialists.

PMID: 35158479
Journal: Multiple Sclerosis and Related Disorders
Year: 2022
Reference: Mult Scler Relat Disord. 2022 Jan;57:103389. doi: 10.1016/j.msard.2021.103389. Epub 2021 Nov 13.
Impact factor:
Publication type: Paper in international publication
Authors: Amato, Maria Pia; Andhavarapu, Sanketh; Bermel, Robert; Caceres, Fernando; Celius, Elisabeth Gulowsen; Costa, Andreia; Fernandez, Oscar; Foss, Mona; Havrdova, Eva Kubala; Kalincik, Tomas et al.
DOI: 10.1016/j.msard.2021.103389

The frequency and characteristics of MS misdiagnosis in patients referred to the multiple sclerosis centre of Catalonia.

PMID: 33565909
Journal: Multiple Sclerosis Journal
Year: 2021
Reference: Mult Scler. 2021 May;27(6):913-921. doi: 10.1177/1352458520988148. Epub 2021 Feb 10.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Carvajal, Rene; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Midaglia, Luciana; Montalban, Xavier; Nos, Carlos; Pappolla, Agustin et al.
DOI: 10.1177/1352458520988148

Foveal changes in AQP4-Ab seropositive NMOSD are independent of optic neuritis and not overtly progressive.

PMID: 33547839
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2021
Reference: Eur J Neurol. 2021 Jul;28(7):2280-2293. doi: 10.1111/ene.14766. Epub 2021 Mar 23.
Impact factor:
Publication type: Paper in international publication
Authors: Asseyer, Susanna; Bellmann-Strobl, Judith; Brandt, Alexander Ulrich; Craner, Matthew J; Kuchling, Joseph; Leite, Maria Isabel; Motamedi, Sedamirhosein; Oertel, Frederike Cosima; Palace, Jacqueline; Paul, Friedemann et al.
DOI: 10.1111/ene.14766

Assessing and mitigating risk of infection in patients with multiple sclerosis on disease modifying treatment.

PMID: 33543657
Journal: Expert Review of Clinical Immunology
Year: 2021
Reference: Expert Rev Clin Immunol. 2021 Mar;17(3):285-300. doi: 10.1080/1744666X.2021.1886924. Epub 2021 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Otero-Romero, Susana; Sanchez-Montalva, Adrian; Vidal-Jordana, Angela et al.
DOI: 10.1080/1744666X.2021.1886924

Optic nerve region in multiple sclerosis diagnosis: the utility of visual evoked potentials.

PMID: 33328323
Journal: NEUROLOGY
Year: 2021
Reference: Neurology. 2021 Jan 26;96(4):e482-e490. doi: 10.1212/WNL.0000000000011339. Epub 2020 Dec 16.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Cabello, Sergio; Castillo, Joaquin; Comabella, Manuel; Galan, Ingrid; Midaglia, Luciana; Moncho, Dulce; Montalban, Xavier; Nos, Carlos et al.
DOI: 10.1212/WNL.0000000000011339

The ACROSS study: Long-term efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis.

PMID: 32284874
Journal: Multiple sclerosis journal - experimental, transla
Year: 2020
Reference: Mult Scler J Exp Transl Clin. 2020 Mar 30;6(1):2055217320907951. doi: 10.1177/2055217320907951. eCollection 2020 Jan-Mar.
Impact factor:
Publication type: Paper in international publication
Authors: Azmon, A; Derfuss, T; Gaetano, L; Kappos, L; Montalban, X; Rodegher, M; Sastre-Garriga, J; Tomic, D; Wolf, C; Wuerfel, J et al.
DOI: 10.1177/2055217320907951

Italian consensus on treatment of spasticity in multiple sclerosis.

PMID: 31652369
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2020
Reference: Eur J Neurol. 2020 Mar;27(3):445-453. doi: 10.1111/ene.14110. Epub 2019 Dec 3.
Impact factor:
Publication type: Paper in international publication
Authors: Amadeo, Roberta; Amato, Maria Pia; Bertolotto, Antonio; Boffa, Laura; Brichetto, Giampaolo; Centonze, D; Comi, G; Comola, Mauro; Ghezzi, Angelo; Leocani, L et al.
DOI: 10.1111/ene.14110

NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.

PMID: 32282893
Journal: BRAIN
Year: 2020
Reference: Brain. 2020 May 1;143(5):1414-1430. doi: 10.1093/brain/awaa084.
Impact factor:
Publication type: Paper in international publication
Authors: Amman, Lukas; Calvo-Barreiro, Laura; Castillo, Joaquin; Clemente, Diego; Comabella, Manuel; Costa, Carme; Eixarch, Herena; Espejo, Carmen; Fissolo, Nicolas; Keller, Christian W et al.
DOI: 10.1093/brain/awaa084

A Commercial Probiotic Induces Tolerogenic and Reduces Pathogenic Responses in Experimental Autoimmune Encephalomyelitis.

PMID: 32272791
Journal: Cells
Year: 2020
Reference: Cells. 2020 Apr 7;9(4). pii: cells9040906. doi: 10.3390/cells9040906.
Impact factor:
Publication type: Paper in international publication
Authors: Calvo-Barreiro, Laura; Castillo, Mireia; Clemente, Diego; Del Campo, Rosa; Eixarch, Herena; Espejo, Carmen; Guaza, Carmen; Lebron-Galan, Rafael; Mestre, Leyre; Montalban, Xavier et al.
DOI: 10.3390/cells9040906

Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG.

PMID: 31043474
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 May 28;92(22):e2538-e2549. doi: 10.1212/WNL.0000000000007572. Epub 2019 May 1.
Impact factor: 8.689
Publication type: Paper in international publication
Authors: Waubant, Emmanuelle, Banwell, Brenda, Wassmer, Evangeline, Sormani, Maria-Pia, Amato, Maria-Pia, Hintzen, Rogier, Krupp, Lauren, Rostasy, Kevin, Tenembaum, Silvia, Chitnis, Tanuja et al.
DOI: 10.1212/WNL.0000000000007572

Multiple Sclerosis Lesion Synthesis in MRI Using an Encoder-Decoder U-NET

PMID: NOPMID0063
Journal: IEEE Access
Year: 2019
Reference: IEEE Access. 2019;7:25171-84. doi: 10.1109/ACCESS.2019.2900198
Impact factor: 4.098
Publication type: Paper in international publication
Authors: Salem, Mostafa, Valverde, Sergi, Cabezas, Mariano, Pareto Onghena, Deborah, Oliver, Arnau, Salvi, Joaquim, Rovira Cañellas, Alex, Llado, Xavier et al.
DOI: 10.1109/ACCESS.2019.2900198

Correction: Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

PMID: 31596725
Journal: JOURNAL OF MEDICAL INTERNET RESEARCH
Year: 2019
Reference: J Med Internet Res. 2019 Oct 8;21(10):e16287. doi: 10.2196/16287.
Impact factor: 4.945
Publication type: Letter or abstract
Authors: Midaglia, Luciana, Mulero, Patricia, Montalban, Xavier, Graves, Jennifer, Hauser, Stephen L, Julian, Laura, Baker, Michael, Schadrack, Jan, Gossens, Christian, Scotland, Alf et al.
DOI: 10.2196/16287

Adherence and Satisfaction of Smartphone- and Smartwatch-Based Remote Active Testing and Passive Monitoring in People With Multiple Sclerosis: Nonrandomized Interventional Feasibility Study.

PMID: 31471961
Journal: JOURNAL OF MEDICAL INTERNET RESEARCH
Year: 2019
Reference: J Med Internet Res. 2019 Aug 30;21(8):e14863. doi: 10.2196/14863.
Impact factor: 4.945
Publication type: Paper in international publication
Authors: Midaglia, Luciana, Mulero, Patricia, Montalban, Xavier, Graves, Jennifer, Hauser, Stephen L, Julian, Laura, Baker, Michael, Schadrack, Jan, Gossens, Christian, Scotland, Alf et al.
DOI: 10.2196/14863

Combined therapies to treat complex diseases: The role of the gut microbiota in multiple sclerosis.

PMID: 29191793
Journal: AUTOIMMUNITY REVIEWS
Year: 2018
Reference: Autoimmun Rev. 2018 Feb;17(2):165-174. doi: 10.1016/j.autrev.2017.11.019. Epub 2017 Nov 28.
Impact factor:
Publication type: Review in international publication
Authors: Calvo-Barreiro, Laura; Eixarch, Herena; Espejo, Carmen; Montalban, Xavier et al.
DOI: 10.1016/j.autrev.2017.11.019

Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study.

PMID: 29275979
Journal: LANCET NEUROLOGY
Year: 2018
Reference: Lancet Neurol. 2018 Feb;17(2):133-142. doi: 10.1016/S1474-4422(17)30469-6. Epub 2017 Dec 21.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Brownlee, Wallace; Ciccarelli, Olga; Comi, Giancarlo; Cramer, Stig P; Dekker, Iris; Drulovic, Jelena; Dujmovic-Basuroski, Irena; Enzinger, Christian; Filippi, Massimo et al.
DOI: 10.1016/S1474-4422(17)30469-6

Classic Block Design "Pseudo"-Resting-State fMRI Changes After a Neurorehabilitation Program in Patients with Multiple Sclerosis.

PMID: 29400912
Journal: JOURNAL OF NEUROIMAGING
Year: 2018
Reference: J Neuroimaging. 2018 May;28(3):313-319. doi: 10.1111/jon.12500. Epub 2018 Feb 5.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Juli; Arevalo, Maria Jesus; Galan, Ingrid; Montalban, Xavier; Pareto, Deborah; Renom, Marta; Rovira, Alex; Sastre-Garriga, Jaume et al.
DOI: 10.1111/jon.12500

Multiple sclerosis risk perception and acceptance for Brazilian patients.

PMID: 29364388
Journal: ARQUIVOS DE NEURO-PSIQUIATRIA
Year: 2018
Reference: Arq Neuropsiquiatr. 2018 Jan;76(1):6-12. doi: 10.1590/0004-282X20170167.
Impact factor:
Publication type: Paper in international publication
Authors: Bichuetti, Denis Bernardi; Carvalho, Lorraine Fiama Diniz; Diniz, Denise Sisterolli; Elias, Isaac; Franco, Carolina Azze; Mendonca, Andreia C R; Oliveira, Enedina Maria Lobato de; Tintore, Mar; Tur, Carmen et al.
DOI: 10.1590/0004-282X20170167

DNA Vaccination Techniques.

PMID: 24973869
Journal: ARTIFICIAL LIFE
Year: 2016
Reference: Methods Mol Biol. 2016;1304:39-50. doi: 10.1007/7651_2014_87.
Impact factor:
Publication type: Editorail in international publication
Authors: Comabella, Manuel; Fissolo, Nicolas; Montalban, Xavier et al.
DOI: 10.1007/7651_2014_87

A 10-year follow-up of the European multicenter trial of interferon beta-1b in secondary-progressive multiple sclerosis.

PMID: 26362898
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Apr;22(4):533-43. doi: 10.1177/1352458515594440. Epub 2015 Sep 11.
Impact factor: 4.822
Publication type: Paper in international publication
Authors: Gugleta, K, Ecsedi, M, Lienert, C, Amato, M P, Baum, K, Buttmann, M, Bayas, A, Brassat, D, Brochet, B, Confavreux, C et al.
DOI: 10.1177/1352458515594440

MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes.

PMID: 26604134
Journal: HUMAN MOLECULAR GENETICS
Year: 2016
Reference: Hum Mol Genet. 2016 Jan 15;25(2):308-16. doi: 10.1093/hmg/ddv473. Epub 2015 Nov 24.
Impact factor: 5.985
Publication type: Paper in international publication
Authors: Comabella, Manuel, Canto, Ester, Nurtdinov, Ramil, Rio, Jordi, Villar, Luisa M, Picon, Carmen, Castillo, Joaquin, Fissolo, Nicolas, Aymerich, Xavier, Auger, Cristina et al.
DOI: 10.1093/hmg/ddv473

Structural MRI correlates of cognitive impairment in patients with multiple sclerosis: A Multicenter Study.

PMID: 26833969
Journal: HUMAN BRAIN MAPPING
Year: 2016
Reference: Hum Brain Mapp. 2016 Apr;37(4):1627-44. doi: 10.1002/hbm.23125. Epub 2016 Feb 2.
Impact factor: 4.962
Publication type: Paper in international publication
Authors: Preziosa, Paolo, Rocca, Maria A, Pagani, Elisabetta, Stromillo, Maria Laura, Enzinger, Christian, Gallo, Antonio, Hulst, Hanneke E, Atzori, Matteo, Pareto, Deborah, Riccitelli, Gianna C et al.
DOI: 10.1002/hbm.23125

Role of high mobility group box protein 1 (HMGB1) in peripheral blood from patients with multiple sclerosis.

PMID: 25879961
Journal: J NEUROINFLAMM
Year: 2015
Reference: J Neuroinflammation. 2015 Mar 11;12:48. doi: 10.1186/s12974-015-0269-9.
Impact factor:
Publication type: Paper in international publication
Authors: Castillo, Joaquin; Comabella, Manuel; Fissolo, Nicolas; Malhotra, Sunny; Montalban, Xavier; Tintore, Mar; Vidal-Jordana, Angela; Wing, Ana Cristina et al.
DOI: 10.1186/s12974-015-0269-9

Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.

PMID: 26079949
Journal: CLIN IMMUNOL
Year: 2015
Reference: Clin Immunol. 2015 Oct;160(2):133-41. doi: 10.1016/j.clim.2015.06.004. Epub 2015 Jun 12.
Impact factor:
Publication type: Paper in international publication
Authors: Canto, Ester; Comabella, Manuel; Costa, Carme; Espejo, Carmen; Montalban, Xavier et al.
DOI: 10.1016/j.clim.2015.06.004

Radiologic MS disease activity during natalizumab treatment interruption: findings from RESTORE.

PMID: 25381458
Journal: J NEUROL
Year: 2015
Reference: J Neurol. 2015 Feb;262(2):326-36. doi: 10.1007/s00415-014-7558-6. Epub 2014 Nov 9.
Impact factor:
Publication type: Paper in international publication
Authors: Campagnolo, Denise; Cree, Bruce A C; De Seze, Jerome; Duda, Petra; Fox, Robert J; Gold, Ralf; Hartung, Hans-Peter; Jeffery, Douglas; Kappos, Ludwig; Kaufman, Michael et al.
DOI: 10.1007/s00415-014-7558-6

Assessment of the reproducibility of oligoclonal IgM band detection for its application in daily clinical practice.

PMID: 25110815
Journal: CLIN CHIM ACTA
Year: 2015
Reference: Clin Chim Acta. 2015 Jan 1;438:67-9. doi: 10.1016/j.cca.2014.08.004. Epub 2014 Aug 8.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, V; Alvarez-Cermeno, J C; Arroyo, R; Bau, L; Camara, C; Campos-Ruiz, L; Casanova, B; Espejo, C; Espino, M; Fernandez, O et al.
DOI: 10.1016/j.cca.2014.08.004

Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration.

PMID: 23812283
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Jan;20(1):72-80. doi: 10.1177/1352458513492245. Epub 2013 Jun 27.
Impact factor:
Publication type: Paper in international publication
Authors: Altmann, Dr; Balk, L; Barkhof, F; Chard, Dt; Ciccarelli, O; Filippi, M; Gasperini, C; Geurts, Jjg; Kappos, L; Kearney, H et al.
DOI: 10.1177/1352458513492245

Multiple sclerosis in 2013: Novel triggers, treatment targets and brain atrophy measures.

PMID: 24394287
Journal: Nature Reviews Neurology
Year: 2014
Reference: Nat Rev Neurol. 2014 Feb;10(2):72-3. doi: 10.1038/nrneurol.2013.274. Epub 2014 Jan 7.
Impact factor:
Publication type: Review in international publication
Authors: Montalban, Xavier; Tintore, Mar et al.
DOI: 10.1038/nrneurol.2013.274

[Current description of multiple sclerosis].

PMID: 25732942
Journal: MED CLIN-BARCELONA
Year: 2014
Reference: Med Clin (Barc). 2014 Dec;143 Suppl 3:3-6. doi: 10.1016/S0025-7753(15)30002-6.
Impact factor: 1.252
Publication type: Review in national publication
Authors: Rio, Jordi, Montalban, Xavier et al.
DOI: 10.1016/S0025-7753(15)30002-6

Kinetic analysis of [11C]vorozole binding in the human brain with positron emission tomography.

PMID: 24824855
Journal: MOL IMAGING
Year: 2014
Reference: Mol Imaging. 2014 May;13(3):1-12.
Impact factor: 2.191
Publication type: Paper in international publication
Authors: Logan, Jean, Kim, Sung Won, Pareto, Deborah, Telang, Frank, Wang, Gene-Jack, Fowler, Joanna S, Biegon, Anat et al.
DOI:

Optimization of [(11)C]raclopride positron emission tomographic rat studies: comparison of methods for image quantification.

PMID: 23651503
Journal: Molecular Imaging
Year: 2013
Reference: Mol Imaging. 2013 Jun;12(4):257-62.
Impact factor: 3.408
Publication type: Paper in international publication
Authors: Pareto, Deborah, Ruiz, Alba, Gispert, Juan Domingo, Millan, Olga, Torrent, Elia, Farre, Magi, Abasolo, Ibane, Llop, Jordi et al.
DOI:

Clinical impact of early brain atrophy in clinically isolated syndromes.

PMID: 23652215
Journal: Multiple Sclerosis Journal
Year: 2013
Reference: Mult Scler. 2013 Dec;19(14):1878-86. doi: 10.1177/1352458513488231. Epub 2013 May 7.
Impact factor: 4.472
Publication type: Paper in international publication
Authors: Montalban, X, Rovira, A, Huerga, E, Auger, C, Perez-Miralles, F, Sastre-Garriga, J, Tintore, M, Arrambide, G, Nos, C, Perkal, H et al.
DOI: 10.1177/1352458513488231

Baseline gene expression signatures in monocytes from multiple sclerosis patients treated with interferon-beta.

PMID: 23637780
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Apr 18;8(4):e60994. doi: 10.1371/journal.pone.0060994. Print 2013.
Impact factor: 3.73
Publication type: Paper in international publication
Authors: Montalban, Xavier, Bustamante, Marta F, Nurtdinov, Ramil N, Rio, Jordi, Comabella, Manuel et al.
DOI: 10.1371/journal.pone.0060994

Erythrocytes labeled with [(18) F]SFB as an alternative to radioactive CO for quantification of blood volume with PET.

PMID: 23613441
Journal: Contrast Media & Molecular Imaging
Year: 2013
Reference: Contrast Media Mol Imaging. 2013 Jul-Aug;8(4):375-81. doi: 10.1002/cmmi.1533.
Impact factor: 2.872
Publication type: Paper in international publication
Authors: Gispert, Juan Domingo, Abad, Sergio, Victor, Victor M, Pareto, Deborah, Torrent, Elia, Rojas, Santiago, Herance, Jose Raul et al.
DOI: 10.1002/cmmi.1533

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In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

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Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

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