About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
IP: Maria Jose Soler Romeo Collaborators: Laura Donadeu Casassas, Oriol Bestard Matamoros, Elena Isabel Crespo Gimeno Funding agency: Fundació La Marató de TV3 Funding: 199935.54 Reference: 202037-31 Duration: 01/06/2021 - 31/12/2024
IP: Maria Jose Soler Romeo Collaborators: - Funding agency: Fundació La Marató de TV3 Funding: 154125 Reference: 202133-30 Duration: 23/09/2021 - 22/09/2024
IP: Oriol Bestard Matamoros Collaborators: The EUropean TRAnsplantation and INnovation (EU-TRAIN) consortium for improving diagnosis and risk stratification in kidney tran, Elena Isabel Crespo Gimeno, Delphine Kervella Funding agency: EUROPEAN COMMISSION Funding: 835583.76 Reference: EUTRAIN_H2020-SC12017 Duration: 01/01/2018 - 30/06/2024
IP: Josefina Cortes Hernandez Collaborators: Teresa Moline Marimon, Sheila Bermejo Garcia Funding agency: Instituto de Salud Carlos III Funding: 141570 Reference: PI21/00287 Duration: 01/01/2022 - 31/12/2024
PMID: 38025231 Journal: Kidney International Reports Year: 2023 Reference: Kidney Int Rep. 2023 Sep 20;8(11):2492. doi: 10.1016/j.ekir.2023.08.011. eCollection 2023 Nov. Impact factor: Publication type: Paper in international publication Authors: Aguasca, Gerard Marti; Alujas, Teresa Gonzalez; Barcelo, Maria Calvo; Barrabes, Jose A; Belahnech, Yassin; Bellera, Neus; Calabuig, Alvaro; Fernandez-Galera, Ruben; Galian-Gay, Laura; Garcia Del Blanco, Bruno et al. DOI: 10.1016/j.ekir.2023.08.011
PMID: 38032448 Journal: JOURNAL OF CLINICAL MONITORING AND COMPUTING Year: 2023 Reference: J Clin Monit Comput. 2023 Nov 30. doi: 10.1007/s10877-023-01110-5. Impact factor: Publication type: Paper in international publication Authors: Corbett, Matthew; Gonzalez-Suarez, Susana; Hernandez-Martinez, Alberto; Lopez-Martinez, Marina; Machado, Miriam; Rico-Fontalvo, Jorge; Soler, Maria Jose et al. DOI: 10.1007/s10877-023-01110-5
PMID: 38030066 Journal: Year: 2023 Reference: J Sport Health Sci. 2023 Nov 27:S2095-2546(23)00115-1. doi: 10.1016/j.jshs.2023.11.006. Impact factor: Publication type: Paper in international publication Authors: Alejo, Lidia B; Barranco-Gil, David; Bestard, Oriol; Bustos, Asuncion; Castellote-Belles, Laura; Couzi, Lionel; Fernandez-Ruiz, Mario; Ferrer-Costa, Roser; Kaminski, Hannah; Lucia, Alejandro et al. DOI: 10.1016/j.jshs.2023.11.006
PMID: 38053242 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2023 Reference: J Am Soc Nephrol. 2023 Dec 6. doi: 10.1681/ASN.0000000000000260. Impact factor: Publication type: Paper in international publication Authors: Al-Awadhi, Solaf; Aubert, Olivier; Bailly, Elodie; Bestard, Oriol; Bouquegneau, Antoine; Collins, Gary; Del Bello, Arnaud; Demir, Zeynep; Divard, Gillian; Friedewald, John J et al. DOI: 10.1681/ASN.0000000000000260
PMID: 35497798 Journal: Kidney International Reports Year: 2022 Reference: Kidney Int Rep. 2021 Dec 16;7(4):797-809. doi: 10.1016/j.ekir.2021.11.037. eCollection 2022 Apr. Impact factor: 4.164 Publication type: Paper in international publication Authors: Bauer, Colin, Piani, Federica, Banks, Mindy, Ordonez, Flor A, de Lucas-Collantes, Carmen, Oshima, Kaori, Schmidt, Eric P, Zakharevich, Igor, Segarra, Alfons, Martinez, Cristina et al. DOI: 10.1016/j.ekir.2021.11.037
PMID: 35475363 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27. Impact factor: 6.312 Publication type: Paper in international publication Authors: Arrambide, Georgina, Otero-Romero, Susana, Pappolla, Agustin, Tagliani, Paula, Lopez-Maza, Samuel, Cardenas-Robledo, Simon, Esperalba, Juliana, Fernandez-Naval, Candela, Martinez-Gallo, Monica, Castillo, Mireia et al. DOI: 10.1177/13524585221089540
PMID: 33547795 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Apr 25;37(5):887-894. doi: 10.1093/ndt/gfab034. Impact factor: 5.992 Publication type: Paper in international publication Authors: Garcia-Carro, Clara, Bolufer, Monica, Bury, Roxana, Cataneda, Zaira, Munoz, Eva, Felip, Enriqueta, Lorente, David, Josep Carreras, Maria, Gabaldon, Alejandra, Seron, Daniel et al. DOI: 10.1093/ndt/gfab034
PMID: 35410878 Journal: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Year: 2022 Reference: J Am Soc Nephrol. 2022 Jun;33(6):1223-1224. doi: 10.1681/ASN.2022020164. Epub 2022 Apr 11. Impact factor: 10.121 Publication type: Letter or abstract Authors: Specks, Ulrich, Casal Moura, Marta, Soler, Maria Jose, Sethi, Sanjeev, Fervenza, Fernando C et al. DOI: 10.1681/ASN.2022020164
PMID: 34217504 Journal: NEFROLOGIA Year: 2021 Reference: Nefrologia (Engl Ed). 2021 May 27. pii: S0211-6995(21)00105-3. doi: 10.1016/j.nefro.2021.04.004. Impact factor: 2.033 Publication type: Letter or abstract Authors: Toapanta, Nestor, Castaneda, Zaira, Zuniga, Jose, Leon-Roman, Juan, Ramos, Natalia, Azancot, Maria, Soler, Maria Jose et al. DOI: 10.1016/j.nefro.2021.04.004
PMID: 34221392 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2021 Mar 15;14(7):1848-1850. doi: 10.1093/ckj/sfab058. eCollection 2021 Jul. Impact factor: 4.452 Publication type: Letter or abstract Authors: Segarra Medrano, Alfons, Roig Carcel, Jordi, Estaran, Elena, Abo Rivera, Annabel, Carrera Munoz, Claudia, Gonzalez Rodriguez, Jorge et al. DOI: 10.1093/ckj/sfab058
PMID: 34221369 Journal: Clinical Kidney Journal Year: 2021 Reference: Clin Kidney J. 2020 Feb 10;14(5):1364-1370. doi: 10.1093/ckj/sfaa008. eCollection 2021 May. Impact factor: 4.452 Publication type: Paper in international publication Authors: Oleas, Diana, Bolufer, Monica, Agraz, Irene, Felip, Enriqueta, Munoz, Eva, Gabaldon, Alejandra, Bury, Roxana, Espinel, Eugenia, Seron, Daniel, Garcia-Carro, Clara et al. DOI: 10.1093/ckj/sfaa008
PMID: 34198818 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Jun 5;10(11). pii: jcm10112505. doi: 10.3390/jcm10112505. Impact factor: 4.242 Publication type: Review in international publication Authors: Bermejo, Sheila, Garcia-Carro, Clara, Vergara, Ander, Sanchez de la Nieta, M Dolores, Agraz, Irene, Soler, Maria Jose, Sanchez-Fructuoso, Ana I, Azancot, Maria A et al. DOI: 10.3390/jcm10112505
PMID: 32220930 Journal: Clinical Journal of the American Society of Nephrology Year: 2020 Reference: Clin J Am Soc Nephrol. 2020 May 7;15(5):714-716. doi: 10.2215/CJN.03530320. Epub 2020 Mar 27. Impact factor: 6.628 Publication type: Paper in international publication Authors: Swaminathan, Sundar, Sparks, Matthew A, South, Andrew, Welling, Paul, Luther, J Matt, Cohen, Jordana, Byrd, James Brian, Burrell, Louise M, Batlle, Daniel, Tomlinson, Laurie et al. DOI: 10.2215/CJN.03530320
PMID: 32213927 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2020 Reference: Int J Mol Sci. 2020 Mar 24;21(6). pii: ijms21062245. doi: 10.3390/ijms21062245. Impact factor: 4.556 Publication type: Review in international publication Authors: Moreso, Francesc, Sellares, Joana, Soler, Maria Jose, Seron, Daniel et al. DOI: 10.3390/ijms21062245
PMID: 32200864 Journal: KIDNEY INTERNATIONAL Year: 2020 Reference: Kidney Int. 2020 Apr;97(4):805-806. doi: 10.1016/j.kint.2020.01.007. Impact factor: 8.945 Publication type: Letter or abstract Authors: Soler, Maria Jose, Porrini, Esteban, Fernandez-Fernandez, Beatriz, Ortiz, Alberto et al. DOI: 10.1016/j.kint.2020.01.007
PMID: 31822004 Journal: KIDNEY & BLOOD PRESSURE RESEARCH Year: 2020 Reference: Kidney Blood Press Res. 2020;45(1):122-130. doi: 10.1159/000504544. Epub 2019 Dec 10. Impact factor: 1.898 Publication type: Paper in international publication Authors: Sanchez, Juan, Pombas, Beatriz, Rodriguez, Eva, Busto, Marcos, Barrios, Clara, Sans, Laia, Pascual, Julio, Soler, Maria Jose, Gimeno, Javier, Radosevic, Aleksandar et al. DOI: 10.1159/000504544
PMID: 30314840 Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY Year: 2019 Reference: Int J Cardiol. 2019 Jan 15;275:59-64. doi: 10.1016/j.ijcard.2018.10.002. Epub 2018 Oct 3. Impact factor: 3.471 Publication type: Paper in international publication Authors: Perez-Villa, Felix, Mont, Lluis, Soler, Maria Jose, Batlle, Montserrat, Riera, Marta, Campos, Begona, Ortiz-Perez, Jose Tomas, Anguiano, Lidia, Roca-Ho, Heleia, Farrero, Marta et al. DOI: 10.1016/j.ijcard.2018.10.002
PMID: 24602805 Journal: TRANSPLANT REV-ORLAN Year: 2014 Reference: Transplant Rev (Orlando). 2014 Apr;28(2):84-91. doi: 10.1016/j.trre.2014.01.001. Epub 2014 Jan 27. Impact factor: 2.66 Publication type: Review in international publication Authors: Roman, Antonio, Manito, Nicolas, Campistol, Josep Maria, Cuervas-Mons, Valentin, Almenar, Luis, Arias, Manuel, Casafont, Fernando, Del Castillo, Domingo, Crespo-Leiro, Maria G, Delgado, Juan F et al. DOI: 10.1016/j.trre.2014.01.001
PMID: 24463863 Journal: NEFROLOGIA Year: 2014 Reference: Nefrologia. 2014;34(1):53-61. doi: 10.3265/Nefrologia.pre2013.Oct.12272. Impact factor: 1.442 Publication type: Paper in national publication Authors: Segarra, Alfons, Jatem, Elias, Quiles, M Teresa, Arbos, M Antonia, Ostos, Helena, Valtierra, Naiara, Carnicer, Clara, Salcedo, M Teresa et al. DOI: 10.3265/Nefrologia.pre2013.Oct.12272
PMID: 24463862 Journal: NEFROLOGIA Year: 2014 Reference: Nefrologia. 2014;34(1):46-52. doi: 10.3265/Nefrologia.pre2013.Oct.12256. Impact factor: 1.442 Publication type: Paper in national publication Authors: Agraz, Irene, Segarra, Alfons, Jatem, Elias, Quiles, M Teresa, Arbos, M Antonia, Ostos, Helena, Valtierra, Naiara, Carnicer, Clara, Salcedo, M Teresa et al. DOI: 10.3265/Nefrologia.pre2013.Oct.12256
PMID: 24321303 Journal: TRANSPLANT REV-ORLAN Year: 2014 Reference: Transplant Rev (Orlando). 2014 Jan;28(1):21-5. doi: 10.1016/j.trre.2013.10.006. Epub 2013 Oct 26. Impact factor: 2.66 Publication type: Paper in international publication Authors: Ibernon, Meritxell, Moreso, Francesc, Seron, Daniel et al. DOI: 10.1016/j.trre.2013.10.006
A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.
An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.
Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.
