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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Publications

Bariatric Evaluation Through AI: a Survey of Expert Opinions Versus ChatGPT-4 (BETA-SEOV).

PMID: 37889368
Journal: OBESITY SURGERY
Year: 2023
Reference: Obes Surg. 2023 Oct 27. doi: 10.1007/s11695-023-06903-w.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Ariadna; Alqahtani, Aayed R; Billy, Helmuth Thorlakur; Chiappetta, Sonja; Da Silva Ribeiro, Rui Jose; Gawdat, Khaled; Ghanem, Omar M; Haddad, Ashraf; Jazi, Amir Hossein Davarpanah; Kasama, Kazunori et al.
DOI: 10.1007/s11695-023-06903-w

Monitoring of antimicrobial consumption in paediatrics.

PMID: 37923493
Journal: Enfermedades infecciosas y microbiologia clinica (
Year: 2023
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2023 Nov;41(9):527-528. doi: 10.1016/j.eimce.2023.06.005.
Impact factor:
Publication type: Editorail in international publication
Authors: Dimitrova, Emiliya; Elenski, Kiril; Etropolska, Zlatka; Fernandez-Polo, Aurora; Petrisor, Diana Corina; Santos, Javier et al.
DOI: 10.1016/j.eimce.2023.06.005

Stepwise management of COPD: What is next after bronchodilation?

PMID: 37936381
Journal: Therapeutic Advances in Respiratory Disease
Year: 2023
Reference: Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231208630. doi: 10.1177/17534666231208630.
Impact factor:
Publication type: Paper in international publication
Authors: Alcala Gonzalez, Luis Gerardo; Dreher, Michael; Malagelada, Carolina; Matsunaga, Kazuto; Miravitlles, Marc et al.
DOI: 10.1177/17534666231208630

The potential of patient-derived organoids in precision medicine of biliary tract cancer.

PMID: 37992681
Journal: Cell Reports Medicine
Year: 2023
Reference: Cell Rep Med. 2023 Nov 21;4(11):101294. doi: 10.1016/j.xcrm.2023.101294.
Impact factor:
Publication type: Paper in international publication
Authors: Macarulla, Teresa; Malagelada, Carolina; Martin Dominguez, Veronica; Santander, Cecilio; Tian, Tian V; Yanez-Bartolome, Mariana et al.
DOI: 10.1016/j.xcrm.2023.101294

Rumination syndrome, critical review.

PMID: 34023479
Journal: Gastroenterologia y Hepatologia
Year: 2022
Reference: Gastroenterol Hepatol. 2022 Feb;45(2):155-163. doi: 10.1016/j.gastrohep.2021.03.013. Epub 2021 May 21.
Impact factor: 2.102
Publication type: Review in national publication
Authors: Alcala-Gonzalez, L G; Serra, X; Barba, E et al.
DOI: 10.1016/j.gastrohep.2021.03.013

EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a large-scale epidemiological study in Europe.

PMID: 35126668
Journal: Therapeutic Advances in Gastroenterology
Year: 2022
Reference: Therap Adv Gastroenterol. 2022 Feb 2;15:17562848221074204. doi: 10.1177/17562848221074204. eCollection 2022.
Impact factor: 4.409
Publication type: Paper in international publication
Authors: Racca, Francesca; Lucendo, Alfredo J; Santander, Cecilio; Savarino, Edoardo; Guagnozzi, Danila; Perez-Martinez, Isabel; Perello, Antonia; Guardiola-Arevalo, Antonio; Barrio, Jesus; Elena Betore-Glaria, Maria et al.
DOI: 10.1177/17562848221074204

Management of bloating.

PMID: 35143108
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Mar;34(3):e14333. doi: 10.1111/nmo.14333. Epub 2022 Feb 10.
Impact factor: 3.598
Publication type: Review in international publication
Authors: Serra, Jordi et al.
DOI: 10.1111/nmo.14333

Quantitative GC-TCD Measurements of Major Flatus Components: A Preliminary Analysis of the Diet Effect.

PMID: 35161583
Journal: SENSORS
Year: 2022
Reference: Sensors (Basel). 2022 Jan 22;22(3). pii: s22030838. doi: 10.3390/s22030838.
Impact factor: 3.576
Publication type: Paper in international publication
Authors: Freire, Rafael; Mego, Marianela; Oliveira, Luciana Fontes; Mas, Silvia; Azpiroz, Fernando; Marco, Santiago; Pardo, Antonio et al.
DOI: 10.3390/s22030838

Course of disease in patients with microscopic colitis - a European prospective incident cohort study.

PMID: 33433605
Journal: Journal of Crohns & Colitis
Year: 2021
Reference: J Crohns Colitis. 2021 Jul 5;15(7):1174-1183. doi: 10.1093/ecco-jcc/jjab007.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Khalaf, M A R; Bohr, Johan; Cebula, W; Diac, A R; Fernandez-Banares, Fernando; Guagnozzi, Danila; Hjortswang, Henrik; Kupcinskas, Juozas; Lucendo, Alfredo J; Lyutakov, Ivan et al.
DOI: 10.1093/ecco-jcc/jjab007

Deciphering the complex interplay between pancreatic cancer, diabetes mellitus subtypes and obesity/BMI through causal inference and mediation analyses.

PMID: 32409590
Journal: GUT
Year: 2021
Reference: Gut. 2021 Feb;70(2):319-329. doi: 10.1136/gutjnl-2019-319990. Epub 2020 May 14.
Impact factor:
Publication type: Paper in international publication
Authors: Balcells, Joaquim; Barbera, Victor M; Boenink, Rianne; Carrato, Alfredo; Coscia, Claudia; Costello, Eithne; Crnogorac-Jurcevic, Tatjana; Dominguez-Munoz, J Enrique; Farre, Antoni; Fernandez, Alba et al.
DOI: 10.1136/gutjnl-2019-319990

Plasma protein biomarkers for early detection of pancreatic ductal adenocarcinoma.

PMID: 33411965
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2021
Reference: Int J Cancer. 2021 Apr 15;148(8):2048-2058. doi: 10.1002/ijc.33464. Epub 2021 Jan 15.
Impact factor:
Publication type: Paper in international publication
Authors: Carrato, Alfredo; Estudillo Garcia, Lidia; Evangelina Lopez de Maturana, Maria; Kordes, Maximilian; Lohr, Matthias; Malats, Nuria; Molero, Xavier; Nilsson, Magnus; Ploner, Alexander; Real, Francisco X et al.
DOI: 10.1002/ijc.33464

Normative reference values for esophageal high-resolution manometry in healthy adults: A systematic review.

PMID: 32715569
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2021
Reference: Neurogastroenterol Motil. 2021 Jan;33(1):e13954. doi: 10.1111/nmo.13954. Epub 2020 Jul 26.
Impact factor:
Publication type: Review in international publication
Authors: Alcala Gonzalez, Luis G; Bredenoord, Albert J; Oude Nijhuis, Renske A B; Smout, Andreas J P M et al.
DOI: 10.1111/nmo.13954

Correction of Dyssynergic Defecation, but not Fiber Supplementation, Reduces Symptoms of Functional Dyspepsia in Patients With Constipation in a Randomized Trial.

PMID: 31811952
Journal: Clinical Gastroenterology and Hepatology
Year: 2020
Reference: Clin Gastroenterol Hepatol. 2020 Oct;18(11):2463-2470.e1. doi: 10.1016/j.cgh.2019.11.048. Epub 2019 Dec 4.
Impact factor: 8.549
Publication type: Paper in international publication
Authors: Huaman, Jose-Walter, Bendezu, Alvaro, Monrroy, Hugo, Samino, Sara, Accarino, Anna, Saperas, Esteban, Azpiroz, Fernando, Mego, Marianela et al.
DOI: 10.1016/j.cgh.2019.11.048

Responses to the Letter to the Editor by Brusciano et al.

PMID: 32856764
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2020
Reference: Neurogastroenterol Motil. 2020 Sep;32(9):e13981. doi: 10.1111/nmo.13981.
Impact factor: 2.946
Publication type: Letter or abstract
Authors: Whorwell, Peter, Serra, Jordi, Pohl, Daniel, Azpiroz, Fernando, Chiarioni, Giuseppe, Ducrotte, Philippe, Gourcerol, Guillaume, Hungin, Amrit Pali S, Layer, Peter, Mendive, Juan-Manuel et al.
DOI: 10.1111/nmo.13981

Consensus document on the management preferences of patients with ulcerative colitis: points to consider and recommendations.

PMID: 32804838
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2020
Reference: Eur J Gastroenterol Hepatol. 2020 Dec;32(12):1514-1522. doi: 10.1097/MEG.0000000000001885.
Impact factor: 2.251
Publication type: Paper in international publication
Authors: Casellas, Francesc, Guinard Vicens, Daniel, Garcia-Lopez, Santiago, Gonzalez-Lama, Yago, Arguelles-Arias, Federico, Barreiro-de Acosta, Manuel, Marin Sanchez, Laura, Mendive, Juan Manuel, Saldana, Roberto, Cabez, Ana et al.
DOI: 10.1097/MEG.0000000000001885

Peripheral Corticotropin-Releasing Factor Triggers Jejunal Mast Cell Activation and Abdominal Pain in Patients With Diarrhea-Predominant Irritable Bowel Syndrome.

PMID: 32740086
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2020
Reference: Am J Gastroenterol. 2020 Dec;115(12):2047-2059. doi: 10.14309/ajg.0000000000000789.
Impact factor: 10.171
Publication type: Paper in international publication
Authors: Guilarte, Mar, Vicario, Maria, Martinez, Cristina, de Torres, Ines, Lobo, Beatriz, Pigrau, Marc, Gonzalez-Castro, Ana, Rodino-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina et al.
DOI: 10.14309/ajg.0000000000000789

The experience of inflammatory bowel disease patients with healthcare: A survey with the IEXPAC instrument.

PMID: 30946348
Journal: MEDICINE
Year: 2019
Reference: Medicine (Baltimore). 2019 Apr;98(14):e15044. doi: 10.1097/MD.0000000000015044.
Impact factor: 1.87
Publication type: Paper in international publication
Authors: Marin-Jimenez, Ignacio, Casellas, Francesc, Cortes, Xavier, Garcia-Sepulcre, Mariana F, Julia, Berta, Cea-Calvo, Luis, Soto, Nadia, Navarro-Correal, Ester, Saldana, Roberto, de Toro, Javier et al.
DOI: 10.1097/MD.0000000000015044

Biological Response to Meal Ingestion: Gender Differences.

PMID: 30917512
Journal: Nutrients
Year: 2019
Reference: Nutrients. 2019 Mar 26;11(3). pii: nu11030702. doi: 10.3390/nu11030702.
Impact factor: 4.171
Publication type: Paper in international publication
Authors: Amigo, Nuria, Accarino, Anna, Correig, Xavier, Azpiroz, Fernando, Nieto, Adoracion, Galan, Carmen, Borghi, Giulio, Monrroy, Hugo, Pribic, Teodora et al.
DOI: 10.3390/nu11030702

Non-invasive Prediction of High-risk Varices in Patients with Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.

PMID: 30315285
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2019
Reference: Am J Gastroenterol. 2019 Mar;114(3):446-452. doi: 10.1038/s41395-018-0265-7.
Impact factor: 10.241
Publication type: Paper in international publication
Authors: Tasayco-Huaman, Stephanie, Moctezuma-Velazquez, Carlos, Saffioti, Francesca, Roccarina, Davide, Vargas, Victor, Nilsson, Jan-Erick, Tsochatzis, Emmanuel, Augustin, Salvador, Montano-Loza, Aldo J, Berzigotti, Annalisa et al.
DOI: 10.1038/s41395-018-0265-7

Sequential Changes in the Mesenteric Lymph Node Microbiome and Immune Response during Cirrhosis Induction in Rats.

PMID: 30801032
Journal: mSystems
Year: 2019
Reference: mSystems. 2019 Feb 19;4(1). pii: mSystems00278-18. doi: 10.1128/mSystems.00278-18. eCollection 2019 Jan-Feb.
Impact factor: 6.519
Publication type: Paper in international publication
Authors: Santiago, Alba, Sanchez, Elisabet, Clark, Allison, Pozuelo, Marta, Calvo, Miguel, Yanez, Francisca, Sarrabayrouse, Guillaume, Perea, Lidia, Vidal, Silvia, Gallardo, Alberto et al.
DOI: 10.1128/mSystems.00278-18

Functional neuromuscular impairment in severe intestinal dysmotility.

PMID: 30178519
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Dec;30(12):e13458. doi: 10.1111/nmo.13458. Epub 2018 Sep 3.
Impact factor: 3.842
Publication type: Paper in international publication
Authors: Gallego, Diana, Malagelada, Carolina, Accarino, Anna, Gori, Alessandra, Malagelada, Juan Ramon, Azpiroz, Fernando, De Giorgio, Roberto, Jimenez, Marcel et al.
DOI: 10.1111/nmo.13458

Metabolomic signature of the postprandial experience.

PMID: 30101554
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Dec;30(12):e13447. doi: 10.1111/nmo.13447. Epub 2018 Aug 13.
Impact factor: 3.842
Publication type: Paper in international publication
Authors: Gomez, Josep, Amigo, Nuria, Accarino, Anna, Correig, Xavier, Azpiroz, Fernando, Canellas, Nicolau, Ciccantelli, Barbara, Malagelada, Carolina, Pribic, Teodora et al.
DOI: 10.1111/nmo.13447

Th1-skewed profile and excessive production of proinflammatory cytokines in a NFKB1-deficient patient with CVID and severe gastrointestinal manifestations.

PMID: 30063981
Journal: CLINICAL IMMUNOLOGY
Year: 2018
Reference: Clin Immunol. 2018 Oct;195:49-58. doi: 10.1016/j.clim.2018.07.015. Epub 2018 Jul 29.
Impact factor: 3.557
Publication type: Paper in international publication
Authors: Dieli-Crimi, Romina, Martinez-Gallo, Monica, Franco-Jarava, Clara, Antolin, Maria, Blasco, Laura, Paramonov, Ida, Semidey, Maria E, Fernandez, Antoni Alvarez, Velasquez, Julio, Martin-Nalda, Andrea et al.
DOI: 10.1016/j.clim.2018.07.015

Effects of Prebiotics vs a Diet Low in Fodmaps in Patients with Functional Gut Disorder.

PMID: 29964041
Journal: GASTROENTEROLOGY
Year: 2018
Reference: Gastroenterology. 2018 Oct;155(4):1004-1007. doi: 10.1053/j.gastro.2018.06.045. Epub 2018 Jun 30.
Impact factor: 20.773
Publication type: Paper in international publication
Authors: Huaman, Jose-Walter, Mego, Marianela, Manichanh, Chaysavanh, Canellas, Nicolau, Canueto, Daniel, Segurola, Hegoi, Jansana, Marta, Malagelada, Carolina, Accarino, Anna, Vulevic, Jelena et al.
DOI: 10.1053/j.gastro.2018.06.045

High resolution manometry in patients with idiopathic inflammatory myopathy: Elevated prevalence of esophageal involvement and differences according to autoantibody status and clinical subset.

PMID: 27935079
Journal: MUSCLE & NERVE
Year: 2017
Reference: Muscle Nerve. 2017 Sep;56(3):386-392. doi: 10.1002/mus.25507. Epub 2017 Apr 4.
Impact factor: 2.713
Publication type: Paper in international publication
Authors: Casal-Dominguez, Maria, Pinal-Fernandez, Iago, Mego, Marianela, Accarino, Anna, Jubany, Lluis, Azpiroz, Fernando, Selva-O'Callaghan, Albert et al.
DOI: 10.1002/mus.25507

Effect of Chicory-derived Inulin on Abdominal Sensations and Bowel Motor Function.

PMID: 27680592
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2017
Reference: J Clin Gastroenterol. 2017 Aug;51(7):619-625. doi: 10.1097/MCG.0000000000000723.
Impact factor: 3.163
Publication type: Paper in international publication
Authors: Azpiroz, Fernando, Molne, Laura, Mendez, Sara, Nieto, Adoracion, Manichanh, Chaysavanh, Mego, Marianela, Accarino, Anna, Santos, Javier, Sailer, Manuela, Theis, Stephan et al.
DOI: 10.1097/MCG.0000000000000723

Functional dyspepsia.

PMID: 29099093
Journal: Nature Reviews Disease Primers
Year: 2017
Reference: Nat Rev Dis Primers. 2017 Nov 3;3:17081. doi: 10.1038/nrdp.2017.81.
Impact factor: 6.389
Publication type: Review in international publication
Authors: Azpiroz, Fernando, Enck, Paul, Feinle-Bisset, Christine, Holtmann, Gerald, Lackner, Jeffrey M, Ronkainen, Jukka, Schemann, Michael, Stengel, Andreas, Tack, Jan, Zipfel, Stephan et al.
DOI: 10.1038/nrdp.2017.81

Irritable bowel syndrome diagnosis and management: A simplified algorithm for clinical practice.

PMID: 29026591
Journal: United European Gastroenterology Journal
Year: 2017
Reference: United European Gastroenterol J. 2017 Oct;5(6):773-788. doi: 10.1177/2050640617731968. Epub 2017 Sep 28.
Impact factor: 3.673
Publication type: Review in national publication
Authors: Moayyedi, Paul, Mearin, Fermin, Azpiroz, Fernando, Andresen, Viola, Barbara, Giovanni, Corsetti, Maura, Emmanuel, Anton, Hungin, A Pali S, Layer, Peter, Stanghellini, Vincenzo et al.
DOI: 10.1177/2050640617731968

High Resolution Esophageal Manometry in Patients with Chagas Disease: A Cross-Sectional Evaluation.

PMID: 26848957
Journal: PLoS Neglected Tropical Diseases
Year: 2016
Reference: PLoS Negl Trop Dis. 2016 Feb 5;10(2):e0004416. doi: 10.1371/journal.pntd.0004416. eCollection 2016 Feb.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Mego, Marianela; Molina, Israel; Moris, Maria; Ramirez, Kathleen; Ruiz-de-Leon, Antonio; Salvador, Fernando; Sanchez-Montalva, Adrian et al.
DOI: 10.1371/journal.pntd.0004416

Diabetic neuropathy in the gut: pathogenesis and diagnosis.

PMID: 26643877
Journal: DIABETOLOGIA
Year: 2016
Reference: Diabetologia. 2016 Mar;59(3):404-8. doi: 10.1007/s00125-015-3831-1. Epub 2015 Dec 7.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Malagelada, Carolina et al.
DOI: 10.1007/s00125-015-3831-1

Emergence of linezolid-resistant coagulase-negative staphylococci in an intensive care unit.

PMID: 26670684
Journal:
Year: 2016
Reference: Infect Dis (Lond). 2016;48(5):343-9. doi: 10.3109/23744235.2015.1122225. Epub 2015 Dec 15.
Impact factor:
Publication type: Paper in international publication
Authors: Balandin, Barbara; Fernandez, Inmaculada; Galdos, Pedro; Garcia, Elena; Lobo, Beatriz; Martinez, Rocio; Orden, Beatriz; Ortega, Alfonso; Roman, Federico; Valdivia, Miguel et al.
DOI: 10.3109/23744235.2015.1122225

Mechanism-Oriented Therapy of Irritable Bowel Syndrome.

PMID: 27138605
Journal: ADVANCES IN THERAPY
Year: 2016
Reference: Adv Ther. 2016 Jun;33(6):877-93. doi: 10.1007/s12325-016-0336-3. Epub 2016 Apr 30.
Impact factor: 2.503
Publication type: Review in international publication
Authors: Malagelada, Juan R, Malagelada, Carolina et al.
DOI: 10.1007/s12325-016-0336-3

[Prebiotics: concept, properties and beneficial effects].

PMID: 25659062
Journal: Nutricion Hospitalaria
Year: 2015
Reference: Nutr Hosp. 2015 Feb 7;31 Suppl 1:99-118. doi: 10.3305/nh.2015.31.sup1.8715.
Impact factor: 1.04
Publication type: Paper in national publication
Authors: Redondo-Cuenca, A, Sanz, M L, Clemente, A, Ruperez, P, Ruas-Madiedo, P, Plou, F J, Mateos-Aparicio, I, Corzo, N, Alonso, J L, Azpiroz, F et al.
DOI: 10.3305/nh.2015.31.sup1.8715

Intestinal gas homeostasis: disposal pathways.

PMID: 25581042
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Mar;27(3):363-369. doi: 10.1111/nmo.12498. Epub 2015 Jan 4.
Impact factor: 3.587
Publication type: Paper in international publication
Authors: Mego, M, Bendezu, A, Accarino, A, Malagelada, J-R, Azpiroz, F et al.
DOI: 10.1111/nmo.12498

Intestinal gas content and distribution in health and in patients with functional gut symptoms.

PMID: 26095329
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Sep;27(9):1249-57. doi: 10.1111/nmo.12618. Epub 2015 Jun 21.
Impact factor: 3.587
Publication type: Paper in international publication
Authors: Malagelada, C, Segui, S, Accarino, A, Quiroga, S, Monclus, E, Navazo, I, Malagelada, J-R, Azpiroz, F, Cisternas, D, Burri, E et al.
DOI: 10.1111/nmo.12618

Safety of probiotics and synbiotics in children under 18 years of age.

PMID: 25809217
Journal: Beneficial Microbes
Year: 2015
Reference: Benef Microbes. 2015 Oct 15;6(5):615-30. doi: 10.3920/BM2014.0157. Epub 2015 Apr 22.
Impact factor: 2.614
Publication type: Paper in international publication
Authors: van den Nieuwboer, M, Brummer, R J, Guarner, F, Morelli, L, Cabana, M, Claassen, E et al.
DOI: 10.3920/BM2014.0157

The Spanish Pancreatic Club's recommendations for the diagnosis and treatment of chronic pancreatitis: part 2 (treatment).

PMID: 23395565
Journal: PANCREATOLOGY
Year: 2013
Reference: Pancreatology. 2013 Jan-Feb;13(1):18-28. doi: 10.1016/j.pan.2012.11.310. Epub 2012 Nov 27.
Impact factor: 2.043
Publication type: Paper in international publication
Authors: Farre, A, de-Madaria, E, Abad-Gonzalez, A, Aparicio, J R, Aparisi, L, Boadas, J, Boix, E, de-Las-Heras, G, Dominguez-Munoz, E, Iglesias-Garcia, J et al.
DOI: 10.1016/j.pan.2012.11.310

Impact of orocecal transit time on patient s perception of lactose intolerance.

PMID: 23548006
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2013
Reference: Rev Esp Enferm Dig. 2013 Jan;105(1):13-18.
Impact factor: 1.652
Publication type: Paper in national publication
Authors: Casellas, F, Aparici, A, Casaus, M, Rodriguez, P, Malagelada, J R et al.
DOI:

Diarrhoea-predominant irritable bowel syndrome: an organic disorder with structural abnormalities in the jejunal epithelial barrier.

PMID: 22637702
Journal: GUT
Year: 2013
Reference: Gut. 2013 Aug;62(8):1160-8. doi: 10.1136/gutjnl-2012-302093. Epub 2012 May 25.
Impact factor: 10.732
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1136/gutjnl-2012-302093

[Progress in the knowledge of the intestinal human microbiota].

PMID: 23848071
Journal: Nutricion Hospitalaria
Year: 2013
Reference: Nutr Hosp. 2013 May-Jun;28(3):553-7. doi: 10.3305/nh.2013.28.3.6601.
Impact factor: 1.305
Publication type: Paper in national publication
Authors: Robles-Alonso, Virginia, Guarner, Francisco et al.
DOI: 10.3305/nh.2013.28.3.6601

International validation of a health-related quality of life questionnaire in patients with erosive gastro-oesophageal reflux disease.

PMID: 19183145
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2009
Reference: Aliment Pharmacol Ther. 2009 Mar 15;29(6):615-25.
Impact factor: 1.215
Publication type: Paper in international publication
Authors: Chassany, O, Devault, K R, Schmitt, H, Gebauer, U, Doerfler, H, Malagelada, J R, Holtmann, G et al.
DOI: 10.1111/j.1365-2036.2008.03922.x

Inflammatory disease processes and interactions with nutrition.

PMID: 19586558
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2009
Reference: Br J Nutr. 2009 May;101 Suppl 1:S1-45.
Impact factor: 2.764
Publication type: Review in international publication
Authors: Bourdet-Sicard, R, Calder, P C, Albers, R, Antoine, J-M, Blum, S, Friedmann, P S, Frost, G S, Guarner, F, Lovik, M, Macfarlane, S et al.
DOI: 10.1017/S0007114509377867

Prebiotics, probiotics and helminths: the 'natural' solution?

PMID: 19786773
Journal: DIGESTIVE DISEASES
Year: 2009
Reference: Dig Dis. 2009;27(3):412-7.
Impact factor: 1.092
Publication type: Paper in international publication
Authors: Guarner, Francisco et al.
DOI: 10.1159/000228582

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News

A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.