Skip to main content

Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Publications

Exocrine pancreatic insufficiency following bariatric surgery: unveiling alternative aetiology-case report and short review.

PMID: 37666959
Journal: EUROPEAN JOURNAL OF CLINICAL NUTRITION
Year: 2023
Reference: Eur J Clin Nutr. 2023 Sep 4. doi: 10.1038/s41430-023-01338-z.
Impact factor:
Publication type: Paper in international publication
Authors: Claro, Maria; de Hollanda, Ana; Ibarzabal, Ainitze; Jimenez, Amanda; Leyes, Pere; Milad, Camila; Moize, Violeta; Molero, Xavier; Nunez-Pizarro, Jorge Luis; Vaquero, Eva et al.
DOI: 10.1038/s41430-023-01338-z

[Not Available].

PMID: 37708969
Journal: Gastroenterologia y Hepatologia
Year: 2023
Reference: Gastroenterol Hepatol. 2023 Sep 12:S0210-5705(23)00407-7. doi: 10.1016/j.gastrohep.2023.09.001.
Impact factor:
Publication type: Paper in national publication
Authors: Albeniz, Eduardo; Cuatrecasas, Mirian; Cuatrecasas, Mirian; Guillena, Pedro Delgado; Jimenez Sanchez, Javier; Jimeno, Mireya; Morales, Natalia Garcia; Moreira, Leticia; Sandalinas, Raul Velamazan; Sandalinas, Raul Velamazan et al.
DOI: 10.1016/j.gastrohep.2023.09.001

Assessment of the level III of Inoue by preoperative endoscopic ultrasound and elastography: a novel approach to predict a periarterial divestment technique in borderline resectable (BR) or locally advanced (LA) pancreatic adenocarcinoma-How I do it.

PMID: 37731066
Journal: LANGENBECKS ARCHIVES OF SURGERY
Year: 2023
Reference: Langenbecks Arch Surg. 2023 Sep 21;408(1):367. doi: 10.1007/s00423-023-03105-x.
Impact factor:
Publication type: Paper in international publication
Authors: Abu-Suboh, Monder; Abu-Suboh, Monder; Alberti, Piero; Balsells, Joaquin; Balsells, Joaquin; Charco, Ramon; Charco, Ramon; Macarulla, Teresa; Macarulla, Teresa; Masachs, Miquel et al.
DOI: 10.1007/s00423-023-03105-x

Increased gut permeability and bacterial translocation are associated with fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome: implications for disease-related biomarker discovery.

PMID: 37744357
Journal: Frontiers in Immunology
Year: 2023
Reference: Front Immunol. 2023 Sep 7;14:1253121. doi: 10.3389/fimmu.2023.1253121. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre-Martin, Jose; Alegre-Martin, Jose; Almirall, Miriam; Blanco-Suarez, Manuel; Caceres, Oscar; Castro-Marrero, Jesus; Domingo, Joan Carles; Gonzalez-Castro, Ana Maria; Gonzalez-Castro, Ana Maria; Jurek, Joanna et al.
DOI: 10.3389/fimmu.2023.1253121

Quantitative GC-TCD Measurements of Major Flatus Components: A Preliminary Analysis of the Diet Effect.

PMID: 35161583
Journal: SENSORS
Year: 2022
Reference: Sensors (Basel). 2022 Jan 22;22(3). pii: s22030838. doi: 10.3390/s22030838.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Freire, Rafael; Marco, Santiago; Mas, Silvia; Mego, Marianela; Oliveira, Luciana Fontes; Pardo, Antonio et al.
DOI: 10.3390/s22030838

Management of bloating.

PMID: 35143108
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Mar;34(3):e14333. doi: 10.1111/nmo.14333. Epub 2022 Feb 10.
Impact factor:
Publication type: Review in international publication
Authors: Serra, Jordi et al.
DOI: 10.1111/nmo.14333

EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a large-scale epidemiological study in Europe.

PMID: 35126668
Journal: Therapeutic Advances in Gastroenterology
Year: 2022
Reference: Therap Adv Gastroenterol. 2022 Feb 2;15:17562848221074204. doi: 10.1177/17562848221074204. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Angel; Barrio, Jesus; Blas-Jhon, Leonardo; Carrion, Silvia; Ciriza de Los Rios, Constanza; de la Riva, Susana; Elena Betore-Glaria, Maria; Fernandez-Fernandez, Sonia; Garcia-Morales, Natalia; Guagnozzi, Danila et al.
DOI: 10.1177/17562848221074204

Rumination syndrome, critical review.

PMID: 34023479
Journal: Gastroenterologia y Hepatologia
Year: 2022
Reference: Gastroenterol Hepatol. 2022 Feb;45(2):155-163. doi: 10.1016/j.gastrohep.2021.03.013. Epub 2021 May 21.
Impact factor:
Publication type: Review in national publication
Authors: Alcala-Gonzalez, L G; Barba, E; Serra, X et al.
DOI: 10.1016/j.gastrohep.2021.03.013

Chicago Classification update (v4.0): Technical review of high-resolution manometry metrics for EGJ barrier function.

PMID: 33655610
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2021
Reference: Neurogastroenterol Motil. 2021 Oct;33(10):e14113. doi: 10.1111/nmo.14113. Epub 2021 Mar 2.
Impact factor:
Publication type: Review in international publication
Authors: Bor, Serhat; Kahrilas, Peter J; Kohn, Geoffrey P; Lenglinger, Johannes; Mittal, Ravinder K; Mittal, Sumeet K; Pandolfino, John E; Serra, Jordi; Tatum, Roger; Yadlapati, Rena et al.
DOI: 10.1111/nmo.14113

Evidence of enteric angiopathy and neuromuscular hypoxia in patients with mitochondrial neurogastrointestinal encephalomyopathy.

PMID: 33655764
Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Year: 2021
Reference: Am J Physiol Gastrointest Liver Physiol. 2021 May 1;320(5):G768-G779. doi: 10.1152/ajpgi.00047.2021. Epub 2021 Mar 3.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Boschetti, Elisa; Caio, Giacomo; Carelli, Valerio; Cenacchi, Giovanna; Clavenzani, Paolo; Costa, Roberta; D'Angelo, Roberto; D'Errico, Antonietta; De Giorgio, Roberto et al.
DOI: 10.1152/ajpgi.00047.2021

Gut Microbes and Health.

PMID: 33652061
Journal: Gastroenterologia y Hepatologia
Year: 2021
Reference: Gastroenterol Hepatol. 2021 Aug-Sep;44(7):519-535. doi: 10.1016/j.gastrohep.2021.01.009. Epub 2021 Feb 27.
Impact factor:
Publication type: Review in national publication
Authors: Alvarez, Julia; Guarner, Francisco; Gueimonde, Miguel; Manuel Fernandez Real, Jose; Rodriguez, Juan Miguel; Saenz de Pipaon, Miguel; Sanz, Yolanda et al.
DOI: 10.1016/j.gastrohep.2021.01.009

Corrigendum to "Recomendaciones del Grupo Español de Trabajo en enfermedad de Crohn y colitis ulcerosa (GETECCU) sobre la reservoritis en la colitis ulcerosa. Parte 2: Tratamiento" [Gastroenterología y Hepatología 2020;43(10):649-658]

PMID: 33642094
Journal: Gastroenterologia y Hepatologia
Year: 2021
Reference: Gastroenterol Hepatol. 2021 Apr;44(4):320. doi: 10.1016/j.gastrohep.2021.02.001. Epub 2021 Feb 25.
Impact factor:
Publication type: Letter or abstract
Authors: Barreiro-de Acosta, Manuel; Beltran, Belen; Chaparro, Maria; Espin, Eloy; Ferrer Bradley, Isabel; Gisbert, Javier P; Guarner, Francisco; Gutierrez, Ana; Marin-Jimenez, Ignacio; Nos, Pilar et al.
DOI: 10.1016/j.gastrohep.2021.02.001

European society of neurogastroenterology and motility guidelines on functional constipation in adults.

PMID: 31756783
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2020
Reference: Neurogastroenterol Motil. 2020 Feb;32(2):e13762. doi: 10.1111/nmo.13762. Epub 2019 Nov 22.
Impact factor:
Publication type: Review in international publication
Authors: Azpiroz, Fernando; Chiarioni, Giuseppe; Ducrotte, Philippe; Gourcerol, Guillaume; Hungin, A Pali S; Layer, Peter; Mendive, Juan-Manuel; Pfeifer, Johann; Pohl, Daniel; Rogler, Gerhard et al.
DOI: 10.1111/nmo.13762

A Fermented Milk Product with B. Lactis CNCM I-2494 and Lactic Acid Bacteria Improves Gastrointestinal Comfort in Response to a Challenge Diet Rich in Fermentable Residues in Healthy Subjects.

PMID: 31991794
Journal: Nutrients
Year: 2020
Reference: Nutrients. 2020 Jan 25;12(2). pii: nu12020320. doi: 10.3390/nu12020320.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Barba, Elizabeth; Batet, Ferran Pinsach; Butler, John; Cotillard, Aurelie; de la Torre, Adrian Martinez; Derrien, Muriel; Dornic, Quentin; Faurie, Jean-Michel et al.
DOI: 10.3390/nu12020320

EFFICACY OF THERAPY FOR EOSINOPHILIC ESOPHAGITIS IN REAL-WORLD PRACTICE.

PMID: 31988045
Journal: Clinical Gastroenterology and Hepatology
Year: 2020
Reference: Clin Gastroenterol Hepatol. 2020 Dec;18(13):2903-2911.e4. doi: 10.1016/j.cgh.2020.01.024. Epub 2020 Jan 25.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Angel; Asensio, Teresa; Barrio, Jesus; Casabona, Sergio; de la Riva, Susana; Guagnozzi, Danila; Guardiola, Antonio; Laserna-Mendieta, Emilio J; Lucendo, Alfredo J; Perello, Antonia et al.
DOI: 10.1016/j.cgh.2020.01.024

[Lymphocytic oesophagitis: A rare emerging cause of food impaction].

PMID: 31964566
Journal: Semergen
Year: 2020
Reference: Semergen. 2020 May - Jun;46(4):286-288. doi: 10.1016/j.semerg.2019.11.009. Epub 2020 Jan 18.
Impact factor:
Publication type: Paper in national publication
Authors: Garcia Lopez, C O; Landolfi, S; Lobo, B; Santos, J et al.
DOI: 10.1016/j.semerg.2019.11.009

Risk stratification and treatment of primary biliary cholangitis.

PMID: 30338693
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2019
Reference: Rev Esp Enferm Dig. 2019 Jan;111(1):63-70. doi: 10.17235/reed.2018.5662/2018.
Impact factor: 1.858
Publication type: Review in international publication
Authors: Martinez, Javier, Aguilera, Lara, Albillos, Agustin et al.
DOI: 10.17235/reed.2018.5662/2018

Healthcare Experience and their Relationship with Demographic, Disease and Healthcare-Related Variables: A Cross-Sectional Survey of Patients with Chronic Diseases Using the IEXPAC Scale.

PMID: 30430456
Journal: Patient-Patient Centered Outcomes Research
Year: 2019
Reference: Patient. 2019 Jun;12(3):307-317. doi: 10.1007/s40271-018-0345-1.
Impact factor: 2.673
Publication type: Paper in international publication
Authors: Orozco-Beltran, Domingo, de Toro, Javier, Galindo, Maria J, Marin-Jimenez, Ignacio, Casellas, Francesc, Fuster-RuizdeApodaca, Maria J, Garcia-Vivar, Maria L, Hormigo-Pozo, Antonio, Guilabert, Mercedes, Sanchez-Vega, Nuria et al.
DOI: 10.1007/s40271-018-0345-1

A single faecal microbiota transplantation modulates the microbiome and improves clinical manifestations in a rat model of colitis.

PMID: 31628021
Journal: EBioMedicine
Year: 2019
Reference: EBioMedicine. 2019 Oct;48:630-641. doi: 10.1016/j.ebiom.2019.10.002. Epub 2019 Oct 15.
Impact factor: 6.68
Publication type: Paper in international publication
Authors: Lleal, Marina, Sarrabayrouse, Guillaume, Willamil, Joseane, Santiago, Alba, Pozuelo, Marta, Manichanh, Chaysavanh et al.
DOI: 10.1016/j.ebiom.2019.10.002

Altered host-gut microbes symbiosis in severely malnourished anorexia nervosa (AN) patients undergoing enteral nutrition: An explicative factor of functional intestinal disorders?

PMID: 30527539
Journal: CLINICAL NUTRITION
Year: 2019
Reference: Clin Nutr. 2019 Oct;38(5):2304-2310. doi: 10.1016/j.clnu.2018.10.004. Epub 2018 Oct 9.
Impact factor: 6.402
Publication type: Paper in international publication
Authors: Levenez, Florence, Cournede, Nicole, Dore, Joel, Melchior, Jean-Claude, Pascal, Victoria, Schoenenberger, Andreu, Manichanh, Chaysavanh, Hanachi, Mouna et al.
DOI: 10.1016/j.clnu.2018.10.004

Intermediate Care Unit After Cardiac Surgery: Impact on Length of Stay and Outcomes.

PMID: 29158075
Journal: Revista espanola de cardiologia (English ed.)
Year: 2018
Reference: Rev Esp Cardiol (Engl Ed). 2018 Aug;71(8):638-642. doi: 10.1016/j.rec.2017.10.018. Epub 2017 Nov 20.
Impact factor:
Publication type: Paper in international publication
Authors: Bayes-Genis, Antoni; Berastegui, Elisabet; Camara, Maria-Luisa; Ferrer, Marc; Garcia-Garcia, Cosme; Just, Maria-Soledad; Labata, Carlos; Oliveras, Teresa; Romero, Bernat; Rueda, Ferran et al.
DOI: 10.1016/j.rec.2017.10.018

Randomized Trial of Chronic Pain Self-Management Program in the Community or Clinic for Low-Income Primary Care Patients.

PMID: 29299814
Journal: JOURNAL OF GENERAL INTERNAL MEDICINE
Year: 2018
Reference: J Gen Intern Med. 2018 May;33(5):668-677. doi: 10.1007/s11606-017-4244-2. Epub 2018 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Bobadilla, Raudel; Liang, Yuanyuan; Rodriguez, Natalia; Simmonds, Maureen J; Turner, Barbara J; Yin, Zenong et al.
DOI: 10.1007/s11606-017-4244-2

beta-Blocker treatment and prognosis in acute coronary syndrome associated with cocaine consumption: The RUTI-Cocaine Study.

PMID: 29622456
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2018
Reference: Int J Cardiol. 2018 Jun 1;260:7-10. doi: 10.1016/j.ijcard.2018.02.013.
Impact factor:
Publication type: Paper in international publication
Authors: Bayes-Genis, Antoni; Carrillo, Xavier; Cediel, German; de Diego, Oriol; Ferrer, Marc; Garcia-Garcia, Cosme; Labata, Carlos; Oliveras, Teresa; Rueda, Ferran; Serra, Jordi et al.
DOI: 10.1016/j.ijcard.2018.02.013

"Obstetric violence": Between misunderstanding and mystification.

PMID: 30029826
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology
Year: 2018
Reference: Eur J Obstet Gynecol Reprod Biol. 2018 Sep;228:331. doi: 10.1016/j.ejogrb.2018.06.012. Epub 2018 Jun 15.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Chiantera, Antonio; Colacurci, Nicola; Scambia, Giovanni; Vicario, Maria; Viora, Elsa et al.
DOI: 10.1016/j.ejogrb.2018.06.012

Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome.

PMID: 28164346
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2017
Reference: Aliment Pharmacol Ther. 2017 Apr;45(7):909-922. doi: 10.1111/apt.13958. Epub 2017 Feb 6.
Impact factor:
Publication type: Clinical Trials
Authors: Alonso Cotoner, C; Azpiroz, F; Barbara, G; Barbaro, M R; Bellacosa, L; Bruley des Varannes, S; Cogliandro, R F; Cremon, C; DeFilippis, D; Di Marzo, V et al.
DOI: 10.1111/apt.13958

A microbial signature for Crohn's disease.

PMID: 28179361
Journal: GUT
Year: 2017
Reference: Gut. 2017 May;66(5):813-822. doi: 10.1136/gutjnl-2016-313235. Epub 2017 Feb 7.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Campos, David; Casellas, Francesc; Guarner, Francisco; Machiels, Kathleen; Manichanh, Chaysavanh; Martinez, Xavier; Pascal, Victoria; Pozuelo, Marta; Santiago, Alba et al.
DOI: 10.1136/gutjnl-2016-313235

P327 Evolution after a "de-intensification" strategy with anti-TNF therapy in patients with inflammatory bowel disease in clinical remission: multicenter study.

PMID: 28172730
Journal: Journal of Crohns & Colitis
Year: 2017
Reference: J Crohns Colitis. 2017 Feb 1;11(suppl_1):S243. doi: 10.1093/ecco-jcc/jjx002.452.
Impact factor:
Publication type: Letter or abstract
Authors: Algaba, A; Arguelles-Arias, F; Arias, L; Barreiro-de Acosta, M; Barrio, J; Benitez, J M; Castro, E; Castro, M; Ceballos, D; Chaparro, M et al.
DOI: 10.1093/ecco-jcc/jjx002.452

P423 Early improvement in quality of life in patients with luminal Crohn's disease treated with adalimumab. Data from RAPIDA trial.

PMID: 28175097
Journal: Journal of Crohns & Colitis
Year: 2017
Reference: J Crohns Colitis. 2017 Feb 1;11(suppl_1):S291-S292. doi: 10.1093/ecco-jcc/jjx002.548.
Impact factor:
Publication type: Letter or abstract
Authors: Arguelles-Arias, F; Barreiro-de Acosta, M; Boudet, J M; Busquets, D; Casado, R; Casellas, F; Castro-Laria, L; Ceballos, D; Diaz, G; Echarri, A et al.
DOI: 10.1093/ecco-jcc/jjx002.548

Transcriptional interactions suggest niche segregation among microorganisms in the human gut.

PMID: 27564131
Journal: Nature Microbiology
Year: 2016
Reference: Nat Microbiol. 2016 Aug 26;1:16152. doi: 10.1038/nmicrobiol.2016.152.
Impact factor:
Publication type: Paper in international publication
Authors: Bertalan, Marcelo; Bork, Peer; Brunak, Soren; de Evgrafov, Mari Cristina Rodriguez; Dore, Joel; Ehrlich, S Dusko; Fouqueray, Charlene; Gautier, Laurent; Guarner, Francisco; Hansen, Torben et al.
DOI: 10.1038/nmicrobiol.2016.152

Activation of Immune and Defense Responses in the Intestinal Mucosa by Outer Membrane Vesicles of Commensal and Probiotic Escherichia coli Strains.

PMID: 27242727
Journal: Frontiers in Microbiology
Year: 2016
Reference: Front Microbiol. 2016 May 11;7:705. doi: 10.3389/fmicb.2016.00705. eCollection 2016.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Laura; Alexandra Canas, Maria; Antolin, Maria; Badia, Josefa; Baldoma, Laura; Gimenez, Rosa; Jose Fabrega, Maria; Varela, Encarna et al.
DOI: 10.3389/fmicb.2016.00705

Incongruence between Clinicians' Assessment and Self-Reported Functioning Is Related to Psychopathology among Patients Diagnosed with Gastrointestinal Disorders.

PMID: 27230869
Journal: PSYCHOTHERAPY AND PSYCHOSOMATICS
Year: 2016
Reference: Psychother Psychosom. 2016;85(4):244-5. doi: 10.1159/000443899. Epub 2016 May 27.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Eiroa-Orosa, Francisco Jose; Malagelada, Carolina; Rodriguez-Urrutia, Amanda et al.
DOI: 10.1159/000443899

MetaTrans: an open-source pipeline for metatranscriptomics.

PMID: 27211518
Journal: Scientific Reports
Year: 2016
Reference: Sci Rep. 2016 May 23;6:26447. doi: 10.1038/srep26447.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Campos, David; Guarner, Francisco; Gut, Ivo; Gut, Marta; Manichanh, Chaysavanh; Martinez, Xavier; Pascal, Victoria; Pozuelo, Marta et al.
DOI: 10.1038/srep26447

The administration of probiotics and synbiotics in immune compromised adults: is it safe?

PMID: 25304690
Journal: BENEF MICROBES
Year: 2015
Reference: Benef Microbes. 2015 Mar;6(1):3-17. doi: 10.3920/BM2014.0079.
Impact factor:
Publication type: Paper in international publication
Authors: Brummer, R J; Cabana, M; Claassen, E; Guarner, F; Morelli, L; Van den Nieuwboer, M et al.
DOI: 10.3920/BM2014.0079

World gastroenterology organisation global guidelines: dysphagia--global guidelines and cascades update September 2014.

PMID: 25853874
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2015
Reference: J Clin Gastroenterol. 2015 May-Jun;49(5):370-8. doi: 10.1097/MCG.0000000000000307.
Impact factor: 3.498
Publication type: Paper in international publication
Authors: Malfertheiner, Peter, Salis, Graciela, Sharma, Prateek, Sifrim, Daniel, Vakil, Nimish, Le Mair, Anton, Lindberg, Greger, Kahrilas, Peter, Fried, Michael, De Looze, Danny et al.
DOI: 10.1097/MCG.0000000000000307

The gut microbiome: What do we know?

PMID: 31040957
Journal: Clinical liver disease
Year: 2015
Reference: Clin Liver Dis (Hoboken). 2015 May 7;5(4):86-90. doi: 10.1002/cld.454. eCollection 2015 Apr.
Impact factor: 0
Publication type: Review in international publication
Authors: Guarner, Francisco et al.
DOI: 10.1002/cld.454

The intestinal barrier function and its involvement in digestive disease.

PMID: 26541659
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2015
Reference: Rev Esp Enferm Dig. 2015 Nov;107(11):686-96. doi: 10.17235/reed.2015.3846/2015.
Impact factor: 1.414
Publication type: Review in international publication
Authors: Salvo Romero, Eloisa, Alonso Cotoner, Carmen, Pardo Camacho, Cristina, Casado Bedmar, Maite, Vicario, Maria et al.
DOI: 10.17235/reed.2015.3846/2015

From basic to applied research: lessons from the human microbiome projects.

PMID: 25291122
Journal: J CLIN GASTROENTEROL
Year: 2014
Reference: J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S3-4. doi: 10.1097/MCG.0000000000000242.
Impact factor: 3.186
Publication type: Paper in international publication
Authors: Guarner, Francisco, Robles-Alonso, Virginia et al.
DOI: 10.1097/MCG.0000000000000242

An integrated catalog of reference genes in the human gut microbiome.

PMID: 24997786
Journal: NAT BIOTECHNOL
Year: 2014
Reference: Nat Biotechnol. 2014 Aug;32(8):834-41. doi: 10.1038/nbt.2942. Epub 2014 Jul 6.
Impact factor: 39.08
Publication type: Paper in international publication
Authors: Zhang, Dongya, Zhang, Zhaoxi, Chen, Weineng, Zhao, Hailong, Al-Aama, Jumana Yousuf, Edris, Sherif, Yang, Huanming, Wang, Jian, Hansen, Torben, Nielsen, Henrik Bjorn et al.
DOI: 10.1038/nbt.2942

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.

PMID: 24997787
Journal: NAT BIOTECHNOL
Year: 2014
Reference: Nat Biotechnol. 2014 Aug;32(8):822-8. doi: 10.1038/nbt.2939. Epub 2014 Jul 6.
Impact factor: 39.08
Publication type: Paper in international publication
Authors: Levenez, Florence, Nielsen, Trine, Manichanh, Chaysavanh, Arumugam, Manimozhiyan, Batto, Jean-Michel, Quintanilha Dos Santos, Marcelo B, Blom, Nikolaj, Borruel, Natalia, Burgdorf, Kristoffer S, Boumezbeur, Fouad et al.
DOI: 10.1038/nbt.2939

Microbiome Composition by Pyrosequencing in Mesenteric Lymph Nodes of Rats with CCl-Induced Cirrhosis.

PMID: 24296725
Journal: J INNATE IMMUN
Year: 2014
Reference: J Innate Immun. 2014;6(3):263-71. doi: 10.1159/000356454. Epub 2013 Nov 29.
Impact factor: 4.557
Publication type: Paper in international publication
Authors: Manichanh, Chaysavanh, Guarner, Carlos, Soriano, German, Sancho, Francesc, Cuenca, Silvia, Sanchez, Elisabet, Santiago, Alba, El Khader, Ismail, Panda, Suchita, Vidal, Silvia et al.
DOI: 10.1159/000356454

Acute pancreatitis and superior mesenteric artery syndrome.

PMID: 24641461
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2013
Reference: Rev Esp Enferm Dig. 2013 Nov-Dec;105(10):626-8. doi: 10.4321/s1130-01082013001000009.
Impact factor: 1.652
Publication type: Review in international publication
Authors: Sihuay-Diburga, Denisse Joan, Accarino-Garaventa, Anna, Vilaseca-Montplet, Jaime, Azpiroz-Vidaur, Fernando et al.
DOI: 10.4321/s1130-01082013001000009

Hot topics in gut microbiota.

PMID: 24917977
Journal: United European gastroenterology journal
Year: 2013
Reference: United European Gastroenterol J. 2013 Oct;1(5):311-8. doi: 10.1177/2050640613502477.
Impact factor: 0
Publication type: Review in international publication
Authors: Dore, Joel, Simren, Magnus, Buttle, Lisa, Guarner, Francisco et al.
DOI: 10.1177/2050640613502477

Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.

PMID: 23859454
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2013
Reference: Rev Esp Enferm Dig. 2013 Apr;105(4):232-4. doi: 10.4321/s1130-01082013000400010.
Impact factor: 1.652
Publication type: Paper in international publication
Authors: Castillo-Cejas, Maria Dolores, de-Torres-Ramirez, Ines, Alonso-Cotoner, Carmen et al.
DOI: 10.4321/s1130-01082013000400010

Metagenomic species profiling using universal phylogenetic marker genes.

PMID: 24141494
Journal: NATURE METHODS
Year: 2013
Reference: Nat Methods. 2013 Dec;10(12):1196-9. doi: 10.1038/nmeth.2693. Epub 2013 Oct 20.
Impact factor: 23.565
Publication type: Paper in international publication
Authors: Mende, Daniel R, Zeller, Georg, Izquierdo-Carrasco, Fernando, Berger, Simon A, Kultima, Jens Roat, Coelho, Luis Pedro, Arumugam, Manimozhiyan, Tap, Julien, Nielsen, Henrik Bjorn, Sunagawa, Shinichi et al.
DOI: 10.1038/nmeth.2693

The Jejunum of Diarrhea-Predominant Irritable Bowel Syndrome Shows Molecular Alterations in the Tight Junction Signaling Pathway That Are Associated With Mucosal Pathobiology and Clinical Manifestations.

PMID: 22415197
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2012
Reference: Am J Gastroenterol. 2012 May;107(5):736-46. doi: 10.1038/ajg.2011.472. Epub 2012 Mar 13.
Impact factor: 7.282
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1038/ajg.2011.472

Restoration of quality of life of patients with inflammatory bowel disease after one year with antiTNFalpha treatment.

PMID: 22398074
Journal: Journal of Crohns & Colitis
Year: 2012
Reference: J Crohns Colitis. 2012 Oct;6(9):881-6. doi: 10.1016/j.crohns.2012.01.019. Epub 2012 Feb 14.
Impact factor: 2.566
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1016/j.crohns.2012.01.019

Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction.

PMID: 21641728
Journal: PSYCHONEUROENDOCRINOLOGY
Year: 2012
Reference: Psychoneuroendocrinology. 2012 Jan;37(1):65-77. Epub 2011 Jun 8.
Impact factor: 5.809
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.psyneuen.2011.05.005

Effectiveness of Combined Pharmacologic and Ligation Therapy in High-Risk Patients With Acute Esophageal Variceal Bleeding.

PMID: 21625271
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2011
Reference: Am J Gastroenterol. 2011 Oct;106(10):1787-95. doi: 10.1038/ajg.2011.173. Epub 2011 May 31.
Impact factor: 6.882
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1038/ajg.2011.173

Nursing resources and responsibilities according to hospital organizational model for management of inflammatory bowel disease in Spain.

PMID: 21575883
Journal: Journal of Crohns & Colitis
Year: 2011
Reference: J Crohns Colitis. 2011 Jun;5(3):211-7. Epub 2011 Feb 11.
Impact factor: 2.628
Publication type: Paper in international publication
Authors: Garcia-Sanchez, Valle, Lazaro, Pablo, Alfaro, Noelia, Casellas, Francesc, Marin, Laura, Torrejon, Antonio, Oltra, Lorena, Seoane, Montserrat, Hernandez-Sampelayo, Paloma, Vera, Maria Isabel et al.
DOI: 10.1016/j.crohns.2011.01.001

Abdomino-phrenic dyssynergia in patients with abdominal bloating and distension.

PMID: 21540894
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2011
Reference: Am J Gastroenterol. 2011 May;106(5):815-9.
Impact factor: 6.882
Publication type: Paper in international publication
Authors: Villoria, Albert, Azpiroz, Fernando, Burri, Emanuel, Cisternas, Daniel, Soldevilla, Alfredo, Malagelada, Juan-R et al.
DOI: 10.1038/ajg.2010.408

Enterotypes of the human gut microbiome.

PMID: 21508958
Journal: NATURE
Year: 2011
Reference: Nature. 2011 May 12;473(7346):174-80. Epub 2011 Apr 20.
Impact factor: 36.101
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1038/nature09944

Reshaping the gut microbiome with bacterial transplantation and antibiotic intake.

PMID: 20736229
Journal: GENOME RESEARCH
Year: 2010
Reference: Genome Res. 2010 Oct;20(10):1411-9. Epub 2010 Aug 24.
Impact factor: 11.342
Publication type: Paper in international publication
Authors: Guarner, Francisco, Knight, Rob, Guigo, Roderic, Llopis, Marta, Manichanh, Chaysavanh, Reeder, Jens, Gibert, Prudence, Varela, Encarna, Antolin, Maria et al.
DOI: 10.1101/gr.107987.110

Prebiotic effects: metabolic and health benefits.

PMID: 20920376
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2010
Reference: Br J Nutr. 2010 Aug;104 Suppl 2:S1-63.
Impact factor: 3.446
Publication type: Paper in international publication
Authors: Roberfroid, Marcel, Gibson, Glenn R, Hoyles, Lesley, McCartney, Anne L, Rastall, Robert, Rowland, Ian, Wolvers, Danielle, Watzl, Bernhard, Szajewska, Hania, Stahl, Bernd et al.
DOI: 10.1017/S0007114510003363

Normal values in ambulatory oesophageal pH monitoring at two levels in Spain.

PMID: 20617860
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2010
Reference: Rev Esp Enferm Dig. 2010 Jul;102(7):406-12.
Impact factor: 0.994
Publication type: Paper in national publication
Authors: Mearin, F, Minguez, M, Mones, J, Mora, F, Munoz, C, Perez de la Serna, J, Ponce, J, Rodriguez-Tellez, M, Romero, M J, Ruiz de Leon, A et al.
DOI:

Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress.

PMID: 20600818
Journal: BRAIN BEHAVIOR AND IMMUNITY
Year: 2010
Reference: Brain Behav Immun. 2010 Oct;24(7):1166-75. Epub 2010 Jun 25.
Impact factor: 5.061
Publication type: Paper in international publication
Authors: Vicario, Maria, Guilarte, Mar, Alonso, Carmen, Yang, Pinchang, Martinez, Cristina, Gonzalez, Ana, Guila, Meritxell, Pigrau, Marc, Saperas, Esteban, Azpiroz, Fernando et al.
DOI: 10.1016/j.bbi.2010.06.002

Infliximab maintenance therapy is associated with decreases in direct resource use in patients with luminal or fistulizing Crohn's disease.

PMID: 19448569
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2009
Reference: J Clin Gastroenterol. 2009 Nov-Dec;43(10):950-6.
Impact factor: 2.775
Publication type: Paper in international publication
Authors: Roman, Antonio Lopez-San, Morales, Jose M, Casado, Miguel A, Gisbert, Javier P, Ricart, Elena, Martinez-Montiel, Pilar, Ponce, Marta, Taxonera, Carlos, Rodrigo, Luis, Casellas, Francesc et al.
DOI: 10.1097/MCG.0b013e3181986917

Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's disease mucosa.

PMID: 18839424
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2009
Reference: Inflamm Bowel Dis. 2009 Feb;15(2):275-83.
Impact factor: 4.975
Publication type: Paper in international publication
Authors: Llopis, Marta, Antolin, Maria, Carol, Monica, Borruel, Natalia, Casellas, Francesc, Martinez, Cristina, Espin-Basany, Eloy, Guarner, Francisco, Malagelada, Juan-R et al.
DOI: 10.1002/ibd.20736

Faecal DNA and calprotectin as biomarkers of acute intestinal toxicity in patients undergoing pelvic radiotherapy.

PMID: 19392859
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2009
Reference: Aliment Pharmacol Ther. 2009 Jul 1;30(2):175-85.
Impact factor: 1.215
Publication type: Paper in international publication
Authors: Varela, E, Antolin, M, Guarner, F, Verges, R, Giralt, J, Malagelada, J-R et al.
DOI: 10.1111/j.1365-2036.2009.04019.x

Development, validation, and applicability of a symptoms questionnaire for lactose malabsorption screening.

PMID: 18716868
Journal: DIGESTIVE DISEASES AND SCIENCES
Year: 2009
Reference: Dig Dis Sci. 2009 May;54(5):1059-65.
Impact factor: 1.583
Publication type: Paper in international publication
Authors: Casellas, Francesc, Varela, E, Aparici, A, Casaus, M, Rodriguez, P et al.
DOI: 10.1007/s10620-008-0443-3

Blog

News

A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.