Francesc Xavier Molero Richard Institucions de les que formen part Fisiologia i fisiopatologia digestiva Vall Hebron Institut de Recerca Email Francesc Xavier Molero Richard Email Institucions de les que formen part Fisiologia i fisiopatologia digestiva Vall Hebron Institut de Recerca
Línies de recerca Pathophysiology and treatment of pancreatic disorders. The focus of our research is to study the series of pathophysiologic events leading to acute and chronic pancreatitis and, eventually, pancreatic cancer. We aim to take advantage of knowledge gained at our basic research program to design therapeutic strategies intended to prevent or ameliorate human pancreatic disorders. In rodent models of acute and chronic pancreatitis we examine pancreatic regeneration, fibrogenesis, acino-ductal trandiferentiation, stellate cell activation, epithelial-to-mesenchymal transition and cancer development. In human pancreatitis we investigate environmental and genetic determinants (with special focus at CFTR dysfunction) and new treatment modalities for acute and chronic pancreatitis. IP: Francesc Xavier Molero Richard Projectes New tool based on Artificial Intelligence and Biomarkers for early non-invasive diagnosis of Pancreatic Cancer - AI-Early PanC IP: Stephanie Solange Tasayco Huaman Col·laboradors: Santiago Pérez Hoyos, Francesc Xavier Molero Richard, Joaquin Balsells Valls, Xavier Merino Casabiel, Joan Dot Bach Entitat finançadora: Ministerio Ciencia, Innovación y Universidades Finançament: 293321 Referència: CPP2022-009592 Durada: 01/10/2023 - 31/12/2026 CFTR down regulation enhances pancreatic carcinogenesis and promotes cancer invasion and metastasis IP: Stephanie Solange Tasayco Huaman Col·laboradors: Francesc Xavier Molero Richard, Raquel Ibañez Ferrer Entitat finançadora: Cystic Fibrosis Foundation Finançament: 300565.29 Referència: CFTR_CFF-RESEARCH GRANTS-FALL_2021 Durada: 01/05/2022 - 31/03/2026 Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y metástasis por células estrelladas carentes de CFTR. IP: Francesc Xavier Molero Richard Col·laboradors: Eva Polverino Entitat finançadora: Instituto de Salud Carlos III Finançament: 147620 Referència: PI22/00887 Durada: 01/01/2023 - 01/05/2023 Enhanced fibroinflammatory phenotype of pancreatic stellate cells devoid of CFTR. Exploring pathways for correction. IP: Francesc Xavier Molero Richard Col·laboradors: - Entitat finançadora: Vertex Pharmaceuticals (Spain), S.L. Finançament: 90750 Referència: VERTEX_X.MOLERO_IIS_2020 Durada: 01/02/2020 - 25/05/2023 Paginació Pàgina actual 1 Page 2 Page 3 Page 4 Pàgina següent › Última pàgina »
