Catàleg de biomodels 3D La taula següent mostra els set tipus d’organoides i esferoides desenvolupats al Campus Vall d’Hebron. D’acord amb el seu origen i les seves característiques específiques, es despleguen en quinze models diferenciats, ampliant el ventall de biomodels disponibles per donar suport a la recerca d’una gran varietat de malalties. Reference Type Organoid Disease Class Organism Origin Source of Cells Methodology Used Frozen Organoids Available Research Group OR01 Colon Organoid Colorectal Cancer Tumoral Organoids Mus Musculus Tissue Biopsy Mouse Organoids derived from Intestinal and Colorectal Tumors from Msh2loxP/vCre mouse model Yes Stem Cells & Cancer Group (VHIO) OR02 Colon Organoid Colorectal Cancer Tumoral Organoids Mus Musculus Tissue Biopsy Mouse Organoids derived from Intestinal and Colorectal Tumors from Msh2loxP/vCre/Braf mouse model Yes Stem Cells & Cancer Group (VHIO) OR03 Colon Organoid Colorectal Cancer Tumoral Organoids Mus Musculus Tissue Biopsy Mouse Organoids derived from Intestinal Tumors from vCre/Braf mouse model Yes Stem Cells & Cancer Group (VHIO) OR04 Colon Organoid Colorectal Cancer Tumoral Organoids Homo sapiens Tissue Biopsy Patient derived xenograft from primary CRC Yes Stem Cells & Cancer Group (VHIO) OR05 Colon Organoid Colorectal Cancer Tumoral Organoids Homo sapiens Tissue Biopsy Patient derived xenograft from liver metastasis Yes Stem Cells & Cancer Group (VHIO) OR06 Colon Organoid Colorectal Cancer Tumoral Organoids Homo sapiens Tissue Biopsy Patient derived xenograft from peritoneal metastasis Yes Stem Cells & Cancer Group (VHIO) OR07 Colon Organoid Colorectal Cancer Tumoral Organoids Homo sapiens Tissue Biopsy Patient derived xenograft from clinical trial associace xenograft (CTAX) Yes Stem Cells & Cancer Group (VHIO) OR08 Retinal Organoid Developmental Models Homo sapiens Stem Cells:Induced Pluripotent Stem Cells (iPSCs) 3D organoid differentiation from iPSC cell culture No Oftalmology OR09 Retinal Organoid Patient-Derived Organoids (PDOs) Homo sapiens Stem Cells:Induced Pluripotent Stem Cells (iPSCs) 3D organoid differentiation from iPSC cell culture No Oftalmology OR10 Corneal Organoid Developmental Models Homo sapiens Stem Cells:Induced Pluripotent Stem Cells (iPSCs) 3D organoid differentiation from iPSC cell culture No Oftalmology OR11 Ovarian Organoid Ovarian Cancer Tumoral Organoids Homo sapiens Tissue Biopsy;PDX (Patient-Derived Xenografts) Matrigel cell culture Yes Biomedical Research in Gynaecology OR12 Endometrial Organoid Endometrial Cancer Tumoral Organoids Homo sapiens Tissue Biopsy;PDX (Patient-Derived Xenografts) Matrigel cell culture Yes Biomedical Research in Gynaecology OR13 Endometrial Organoid Other Patient-Derived Organoids (PDOs) Homo sapiens Tissue Biopsy Matrigel cell culture No Biomedical Research in Gynaecology OR14 Intestinal Organoid Cystic Fibrosis Patient-Derived Organoids (PDOs) Homo sapiens Tissue Biopsy Matrigel cell culture Genetics Medicine OR15 Other Cystic Fibrosis Patient-Derived Organoids (PDOs) Homo sapiens Other Genetics Medicine La creació d'aquest catàleg ha estat possible gràcies al finançament de l'Instituto de Salud Carlos III (PT23/00040) en suport a la Recerca Biomèdica, i gràcies als investigadors de la Vall d'Hebron que van proporcionar informació sobre els seus models.També podeu cercar biomodels 3D a la Plataforma de Biomodels i Biobancs de l’ISCIII.
