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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Publications

Clinico-pathological phenotypes of Systemic Sclerosis associated myopathy: analysis of a multicenter large cohort.

PMID: 35713496
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Jun 17. pii: 6609769. doi: 10.1093/rheumatology/keac361.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Prieto-Gonzalez, Sergio, Matas-Garcia, Ana, Guillen-Del-Castillo, Alfredo, Kisluk, Boris, Selva-O'Callaghan, Albert, Espinosa, Gerard, Milisenda, Jose C, Simeon-Aznar, Carmen Pilar, Grau-Junyent, Josep Maria, Garrabou, Gloria et al.
DOI: 10.1093/rheumatology/keac361

Left ventricular diastolic dysfunction in systemic sclerosis: Clinical, immunological and survival differences in the Spanish RESCLE registry.

PMID: 35691226
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2022
Reference: Semin Arthritis Rheum. 2022 Aug;55:152033. doi: 10.1016/j.semarthrit.2022.152033. Epub 2022 May 28.
Impact factor: 5.532
Publication type: Paper in international publication
Authors: Freire, Mayka, Chamorro, Antonio-J, Perales Fraile, Isabel, Madronero Vuelta, Ana Belen, Sanchez Trigo, Sabela, Tolosa Vilella, Carles, Fonollosa Pla, Vicent, Simeon Aznar, Carmen Pilar, Herranz Marin, Maria Teresa, Trapiella Martinez, Luis et al.
DOI: 10.1016/j.semarthrit.2022.152033

Gastrointestinal Involvement in Dermatomyositis.

PMID: 35626355
Journal: Diagnostics
Year: 2022
Reference: Diagnostics (Basel). 2022 May 11;12(5). pii: diagnostics12051200. doi: 10.3390/diagnostics12051200.
Impact factor: 3.706
Publication type: Review in international publication
Authors: Matas-Garcia, Ana, Milisenda, Jose C, Espinosa, Gerard, Cuatrecasas, Miriam, Selva-O'Callaghan, Albert, Grau, Josep Maria, Prieto-Gonzalez, Sergio et al.
DOI: 10.3390/diagnostics12051200

Increase of Circulating Monocyte-Platelet Conjugates in Rheumatoid Arthritis Responders to IL-6 Blockage.

PMID: 35628558
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2022
Reference: Int J Mol Sci. 2022 May 20;23(10). pii: ijms23105748. doi: 10.3390/ijms23105748.
Impact factor: 5.924
Publication type: Paper in international publication
Authors: Mariscal, Anais, Zamora, Carlos, Diaz-Torne, Cesar, Ortiz, M Angels, Agustin, Juan Jose de, Reina, Delia, Estrada, Paula, Moya, Patricia, Corominas, Hector, Vidal, Silvia et al.
DOI: 10.3390/ijms23105748

Clinical Approach to Mast Cell Activation Syndromes: A Practical Overview.

PMID: 33541851
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Investig Allergol Clin Immunol. 2021 Dec 21;31(6):461-470. doi: 10.18176/jiaci.0675. Epub 2020 Feb 5.
Impact factor:
Publication type: Review in international publication
Authors: Escribese, M M; Labrador-Horrillo, M; Longo, N; Luengo-Sanchez, O; Matheu, V; Matito, A; Mayorga, C; Pascal, M; Perez-Gordo, M; Seoane-Reula, M E et al.
DOI: 10.18176/jiaci.0675

Heart Disease in Eosinophilic Granulomatosis with Polyangiitis (EGPA) Patients: a screening approach proposal.

PMID: 33493294
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Oct 2;60(10):4538-4547. doi: 10.1093/rheumatology/keab027.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Vives, Eloi; Harty, Len; Jayne, David; Rodriguez-Palomares, J F; Solans-Laque, Roser et al.
DOI: 10.1093/rheumatology/keab027

Relapse rate and renal prognosis in ANCA-associated vasculitis according to long-term ANCA patterns.

PMID: 33020895
Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Year: 2021
Reference: Clin Exp Immunol. 2021 Feb;203(2):209-218. doi: 10.1111/cei.13530. Epub 2020 Nov 2.
Impact factor:
Publication type: Paper in international publication
Authors: Amengual, Ma Jose; Feijoo, Carlos; Loureiro-Amigo, Jose; Marin, Ana; Monsalvez, Victor; Oristrell, Joaquim; Segarra, Alfons; Solans, Roser; Tolosa, Carles; Valenzuela, Ma Pau et al.
DOI: 10.1111/cei.13530

Omalizumab for the treatment of Chronic Inducible Urticaria in 80 patients.

PMID: 32730636
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2021
Reference: Br J Dermatol. 2021 Jan;184(1):167-168. doi: 10.1111/bjd.19425. Epub 2020 Sep 2.
Impact factor:
Publication type: Letter or abstract
Authors: Aguilera Peiro, P; Baliu-Pique, C; Bonfill Orti, M; Curto Barredo, L; Exposito-Serrano, V; Fernandez Chico, N; Figueras Nart, I; Gimenez-Arnau, A; Gomez Armayones, S; Guilabert Vidal, A et al.
DOI: 10.1111/bjd.19425

Epidemiological profile and north-south gradient driving baseline systemic involvement of primary Sjogren's syndrome.

PMID: 31873754
Journal: RHEUMATOLOGY
Year: 2020
Reference: Rheumatology (Oxford). 2020 Sep 1;59(9):2350-2359. doi: 10.1093/rheumatology/kez578.
Impact factor: 5.606
Publication type: Paper in international publication
Authors: Sanchez-Guerrero, Jorge, Brito-Zeron, Pilar, Acar-Denizli, Nihan, Ng, Wan-Fai, Bootsma, Hendrika, Nakamura, Hideki, Giacomelli, Roberto, Devauchelle-Pensec, Valerie, Hofauer, Benedikt, Bombardieri, Michele et al.
DOI: 10.1093/rheumatology/kez578

Tocilizumab in giant cell arteritis: differences between the GiACTA trial and a multicentre series of patients from the clinical practice.

PMID: 32441643
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2020
Reference: Clin Exp Rheumatol. 2020 Mar-Apr;38 Suppl 124(2):112-119. Epub 2020 May 21.
Impact factor: 3.319
Publication type: Paper in international publication
Authors: Calderon-Goercke, Monica, Castaneda, Santos, Aldasoro, Vicente, Villa, Ignacio, Prieto-Pena, Diana, Atienza-Mateo, Belen, Patino, Esther, Moriano, Clara, Romero-Yuste, Susana, Narvaez, Javier et al.
DOI:

Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis.

PMID: 32843099
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2020
Reference: Arthritis Res Ther. 2020 Aug 25;22(1):196. doi: 10.1186/s13075-020-02287-9.
Impact factor: 4.103
Publication type: Paper in international publication
Authors: Julia, Antonio, Avila, Gabriela, Celis, Raquel, Sanmarti, Raimon, Ramirez, Julio, Marsal, Sara, Canete, Juan D et al.
DOI: 10.1186/s13075-020-02287-9

Anti-HMGCR Specificity of HALIP: A Confirmatory Study.

PMID: 32766318
Journal: Journal of Immunology Research
Year: 2020
Reference: J Immunol Res. 2020 Jul 16;2020:6292631. doi: 10.1155/2020/6292631. eCollection 2020.
Impact factor: 3.327
Publication type: Paper in international publication
Authors: Baucells, Andres, Martinez, Maria Angeles, Alvarado-Cardenas, Marcelo, Mariscal, Anais, Martinez-Martinez, Laura, Juarez, Candido, Selva-O'Callaghan, Albert et al.
DOI: 10.1155/2020/6292631

Nailfold Capillaroscopy Characteristics of Antisynthetase Syndrome and Possible Clinical Associations: Results of a Multicenter International Study.

PMID: 30442823
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2019
Reference: J Rheumatol. 2019 Mar;46(3):279-284. doi: 10.3899/jrheum.180355. Epub 2018 Nov 15.
Impact factor: 3.634
Publication type: Paper in international publication
Authors: Mosca, Marta, Bauhammer, Jutta, Miehle, Nikolaus, Parisi, Simone, Cavagna, Lorenzo, Codullo, Veronica, Montecucco, Carlomaurizio, Lopez-Longo, Francisco Javier, Martinez-Barrio, Julia, Nieto-Gonzalez, Juan Carlos et al.
DOI: 10.3899/jrheum.180355

Pulmonary hypertension in Spanish patients with systemic sclerosis. Data from the RESCLE registry.

PMID: 30535994
Journal: CLINICAL RHEUMATOLOGY
Year: 2019
Reference: Clin Rheumatol. 2019 Apr;38(4):1117-1124. doi: 10.1007/s10067-018-4390-x. Epub 2018 Dec 7.
Impact factor: 2.293
Publication type: Paper in international publication
Authors: Chamorro, A J, Todoli-Parra, Jose A, Rodriguez-Carballeira, Monica, Espinosa-Garriga, Gerard, Colunga-Arguelles, Dolores, Ortego-Centeno, Norberto, Trapiella-Martinez, Luis, Rodero-Roldan, Maria M, Pla-Salas, Xavier, Perales-Fraile, Isabel et al.
DOI: 10.1007/s10067-018-4390-x

Therapeutic strategy according to the differing patient response profiles to omalizumab in chronic spontaneous urticaria.

PMID: 30222111
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2019
Reference: J Investig Allergol Clin Immunol. 2019;29(5):338-348. doi: 10.18176/jiaci.0323. Epub 2018 Sep 17.
Impact factor: 3.802
Publication type: Review in international publication
Authors: Ferrer Puga, M, Silvestre Salvador, F J, Sastre, J, Ortiz de Frutos, J, Miquel Miquel, F J, Gimenez Arnau, A M, Valero Santiago, A, Bartra Tomas, J, Jauregui Presa, I, Labrador-Horrillo, M et al.
DOI: 10.18176/jiaci.0323

ARIA Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.

PMID: 30273709
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2019
Reference: J Allergy Clin Immunol. 2019 Mar;143(3):864-879. doi: 10.1016/j.jaci.2018.08.049. Epub 2018 Sep 29.
Impact factor: 14.11
Publication type: Paper in international publication
Authors: Okubo, Ken, Bousquet, Jean, Hellings, Peter W, Agache, Ioana, Amat, Flore, Annesi-Maesano, Isabella, Ansotegui, Ignacio J, Anto, Josep M, Bachert, Claus, Bateman, Eric D et al.
DOI: 10.1016/j.jaci.2018.08.049

Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.

PMID: 30044938
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 Jul 26;379(4):352-362. doi: 10.1056/NEJMoa1716995.
Impact factor: 79.258
Publication type: Clinical Trials
Authors: Aygoren-Pursun, Emel, Bygum, Anette, Grivcheva-Panovska, Vesna, Magerl, Markus, Graff, Jochen, Maurer, Marcus, Cicardi, Marco, Sheridan, William, Collis, Phil, Fang, Lei et al.
DOI: 10.1056/NEJMoa1716995

Phenotypes, endotypes and biomarkers in anaphylaxis: current insights.

PMID: 30048251
Journal: Current Opinion in Allergy and Clinical Immunology
Year: 2018
Reference: Curr Opin Allergy Clin Immunol. 2018 Oct;18(5):370-376. doi: 10.1097/ACI.0000000000000472.
Impact factor: 3.544
Publication type: Review in international publication
Authors: Sala-Cunill, Anna, Guilarte, Mar, Cardona, Victoria et al.
DOI: 10.1097/ACI.0000000000000472

Management of asthma in the emergency department: a consensus statement.

PMID: 30033702
Journal: Emergencias
Year: 2018
Reference: Emergencias. 2018 Ago;30(4):268-277.
Impact factor: 3.608
Publication type: Paper in international publication
Authors: Pinera Salmeron, Pascual, Delgado Romero, Julio, Dominguez Ortega, Javier, Labrador Horrillo, Moises, Alvarez Gutierrez, Francisco J, Martinez Moragon, Eva, Plaza Moral, Vicente, Alvarez Rodriguez, Cesareo, Miguel Franco, Jose et al.
DOI:

Subclinical cardiovascular disease and Systemic Sclerosis: A comparison between risk charts, quantification of coronary calcium and carotid ultrasonography.

PMID: 30005858
Journal: AUTOIMMUNITY REVIEWS
Year: 2018
Reference: Autoimmun Rev. 2018 Sep;17(9):900-905. doi: 10.1016/j.autrev.2018.03.015. Epub 2018 Jul 11.
Impact factor: 8.745
Publication type: Review in national publication
Authors: Sanz Perez, I, Martinez Valle, F, Guillen Del Castillo, A, Roque Perez, A, Cuellar Calabria, H, Pizzi, M N, Fernandez Codina, A, Callejas Moragas, E, Orozco Galvez, O, Fonollosa Pla, V et al.
DOI: 10.1016/j.autrev.2018.03.015

Lettuce allergy is a lipid transfer syndrome-related food allergy with high risk of severe reactions.

PMID: 27609533
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2017
Reference: J Investig Allergol Clin Immunol. 2017;27(2):98-103. doi: 10.18176/jiaci.0110. Epub 2016 Sep 9.
Impact factor: 2.131
Publication type: Paper in international publication
Authors: Cardona, V, Pastor-Vargas, C, Cuesta-Herranz, J, Moreno-Perez, N, Luengo-Sanchez, O, Munoz-Garcia, E et al.
DOI: 10.18176/jiaci.0110

Immunotherapy in allergic rhinitis and lower airway outcomes.

PMID: 27439141
Journal: ALLERGY
Year: 2017
Reference: Allergy. 2017 Jan;72(1):35-42. doi: 10.1111/all.12989. Epub 2016 Aug 15.
Impact factor: 6.335
Publication type: Paper in international publication
Authors: Luengo, Olga, Cardona, Victoria, Labrador, Moises et al.
DOI: 10.1111/all.12989

Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose escalation, randomised, single-blind, placebo-controlled phase Ib/IIa clinical trial.

PMID: 27269294
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2017
Reference: Ann Rheum Dis. 2017 Jan;76(1):196-202. doi: 10.1136/annrheumdis-2015-208918. Epub 2016 Jun 7.
Impact factor: 12.384
Publication type: Paper in international publication
Authors: Diaz-Gonzalez, Federico, DelaRosa, Olga, Alvaro-Gracia, Jose M, Jover, Juan A, Garcia-Vicuna, Rosario, Carreno, Luis, Alonso, Alberto, Marsal, Sara, Blanco, Francisco, Martinez-Taboada, Victor M et al.
DOI: 10.1136/annrheumdis-2015-208918

Should tumour necrosis factor antagonist safety information be applied from patients with rheumatoid arthritis to psoriasis? Rates of serious adverse events in the prospective rheumatoid arthritis BIOBADASER and psoriasis BIOBADADERM cohorts.

PMID: 27258623
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2017
Reference: Br J Dermatol. 2017 Mar;176(3):643-649. doi: 10.1111/bjd.14776. Epub 2016 Oct 3.
Impact factor: 4.317
Publication type: Paper in international publication
Authors: Rivera, Raquel, Garcia-Doval, I, Hernandez, M V, Vanaclocha, F, Sellas, A, de la Cueva, P, Montero, D, Rodriguez, Basilio, Erausquin, Celia, Rua, Inigo et al.
DOI: 10.1111/bjd.14776

Polypharmacy in elderly people with diabetes admitted to hospital.

PMID: 26607825
Journal: ACTA DIABETOLOGICA
Year: 2016
Reference: Acta Diabetol. 2016 Oct;53(5):857-8. doi: 10.1007/s00592-015-0818-9. Epub 2015 Nov 25.
Impact factor: 3.074
Publication type: Letter or abstract
Authors: Jose, Antonio San, Formiga, Francesc, Agusti, Antonia et al.
DOI: 10.1007/s00592-015-0818-9

PTPN22 is not associated with Behcet's disease. Study spanning the complete gene region in the Spanish population and meta-analysis of the functional variant R620W.

PMID: 27050764
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2016
Reference: Clin Exp Rheumatol. 2016 Sep-Oct;34(6 Suppl 102):S41-S45. Epub 2016 Apr 1.
Impact factor: 2.495
Publication type: Paper in international publication
Authors: Garcia-Lozano, Jose-Raul, Conde-Jaldon, Marta, Ortego-Centeno, Norberto, Gonzalez-Leon, Rocio, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Julia, Maria Rosa, Solans, Roser, Blanco, Ricardo et al.
DOI:

Defining disease activity states and clinically meaningful improvement in primary Sjogren's syndrome with EULAR primary Sjogren's syndrome disease activity (ESSDAI) and patient-reported indexes (ESSPRI).

PMID: 25480887
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2016
Reference: Ann Rheum Dis. 2016 Feb;75(2):382-9. doi: 10.1136/annrheumdis-2014-206008. Epub 2014 Dec 5.
Impact factor: 12.384
Publication type: Paper in international publication
Authors: Praprotnik, Sonja, Sumida, Takayuki, Nishiyama, Sumusu, Caporali, Roberto, Kruize, Aike A, Vollenweider, Cristina, Ravaud, Philippe, Meiners, Petra, Brito-Zeron, Pilar, Vitali, Claudio et al.
DOI: 10.1136/annrheumdis-2014-206008

Systemic activity and mortality in primary Sjogren syndrome: predicting survival using the EULAR-SS Disease Activity Index (ESSDAI) in 1045 patients.

PMID: 25433020
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2016
Reference: Ann Rheum Dis. 2016 Feb;75(2):348-55. doi: 10.1136/annrheumdis-2014-206418. Epub 2014 Nov 28.
Impact factor: 9.27
Publication type: Paper in international publication
Authors: Ramos-Casals, M, Retamozo, S, Gheitasi, H, Morera-Morales, M L, Brito-Zeron, P, Kostov, B, Solans, R, Fraile, G, Casanovas, A, Rascon, F J et al.
DOI: 10.1136/annrheumdis-2014-206418

Variants of the IFI16 gene affecting the levels of expression of mRNA are associated with susceptibility to Behcet disease.

PMID: 25641891
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2015
Reference: J Rheumatol. 2015 Apr;42(4):695-701. doi: 10.3899/jrheum.140949. Epub 2015 Feb 1.
Impact factor: 3.187
Publication type: Paper in international publication
Authors: Ortiz-Fernandez, Lourdes, Garcia-Lozano, Jose-Raul, Montes-Cano, Marco-Antonio, Conde-Jaldon, Marta, Ortego-Centeno, Norberto, Garcia-Hernandez, Francisco-Jose, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Blanco, Ricardo et al.
DOI: 10.3899/jrheum.140949

Delayed diagnosis of late-onset Pompe disease in patients with myopathies of unknown origin and/or hyperCKemia.

PMID: 25752415
Journal: MOLECULAR GENETICS AND METABOLISM
Year: 2015
Reference: Mol Genet Metab. 2015 Apr;114(4):580-3. doi: 10.1016/j.ymgme.2015.02.004. Epub 2015 Feb 21.
Impact factor: 2.625
Publication type: Paper in international publication
Authors: Perez-Lopez, Jordi, Selva-O'Callaghan, Albert, Grau-Junyent, Josep M, Gallego-Galindo, Luis, Coll, M Josep, Garcia-Morillo, Salvador, Torralba-Cabeza, Miguel A, Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.ymgme.2015.02.004

IgG4-Related Disease: Results From a Multicenter Spanish Registry.

PMID: 26266361
Journal: MEDICINE
Year: 2015
Reference: Medicine (Baltimore). 2015 Aug;94(32):e1275. doi: 10.1097/MD.0000000000001275.
Impact factor: 5.723
Publication type: Paper in international publication
Authors: DeTorres, Ines, Solans-Laque, Roser, Fraile-Rodriguez, Guadalupe, Casanovas-Martinez, Arnau, Lopez-Dupla, Miguel, Robles-Marhuenda, Angel, Barragan-Gonzalez, Maria Jesus, Cid, Maria Cinta, Prieto-Gonzalez, Sergio, Brito-Zeron, Pilar et al.
DOI: 10.1097/MD.0000000000001275

Increased humoral immunity in the jejunum of diarrhoea-predominant irritable bowel syndrome associated with clinical manifestations.

PMID: 25209656
Journal: GUT
Year: 2015
Reference: Gut. 2015 Sep;64(9):1379-88. doi: 10.1136/gutjnl-2013-306236. Epub 2014 Sep 10.
Impact factor: 13.319
Publication type: Paper in international publication
Authors: Vicario, Maria, Gonzalez-Castro, Ana M, Martinez, Cristina, Lobo, Beatriz, Pigrau, Marc, Guilarte, Mar, de Torres, Ines, Mosquera, Jose L, Fortea, Marina, Sevillano-Aguilera, Cesar et al.
DOI: 10.1136/gutjnl-2013-306236

GIMAP and Behcet disease: no association in the European population.

PMID: 24625627
Journal: ANN RHEUM DIS
Year: 2014
Reference: Ann Rheum Dis. 2014 Jul;73(7):1433-4. doi: 10.1136/annrheumdis-2013-205156. Epub 2014 Mar 13.
Impact factor: 9.27
Publication type: Letter or abstract
Authors: Ortiz-Fernandez, Lourdes, Conde-Jaldon, Marta, Garcia-Lozano, Jose Raul, Montes-Cano, Marco Antonio, Ortego-Centeno, Norberto, Castillo-Palma, Maria Jesus, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Gonzalez-Gay, Miguel Angel et al.
DOI: 10.1136/annrheumdis-2013-205156

Influence of the IL17A locus in giant cell arteritis susceptibility.

PMID: 24919468
Journal: ANN RHEUM DIS
Year: 2014
Reference: Ann Rheum Dis. 2014 Sep;73(9):1742-5. doi: 10.1136/annrheumdis-2014-205261. Epub 2014 Jun 11.
Impact factor: 9.27
Publication type: Paper in international publication
Authors: Narvaez, J, Gomez-Vaquero, C, Martinez-Taboada, V M, Ortego-Centeno, N, Sopena, B, Monfort, J, Garcia-Villanueva, M J, Caminal-Montero, L, de Miguel, E, Blanco, R et al.
DOI: 10.1136/annrheumdis-2014-205261

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

PMID: 24952504
Journal: NAT IMMUNOL
Year: 2014
Reference: Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22.
Impact factor: 24.973
Publication type: Paper in international publication
Authors: Martin-Sanchez, Fatima, Gomez, Ana I, Martinez, Carlos M, Amores-Iniesta, Joaquin, Compan, Vincent, Barbera-Cremades, Maria, Yague, Jordi, Ruiz-Ortiz, Estibaliz, Anton, Jordi, Bujan, Segundo et al.
DOI: 10.1038/ni.2919

Epistatic interaction of ERAP1 and HLA-B in Behcet disease: a replication study in the Spanish population.

PMID: 25019531
Journal: PLOS ONE
Year: 2014
Reference: PLoS One. 2014 Jul 14;9(7):e102100. doi: 10.1371/journal.pone.0102100. eCollection 2014.
Impact factor: 3.534
Publication type: Paper in international publication
Authors: Solans, Roser, Fanlo, Patricia, Carballeira, Monica Rodriguez, Camps, Teresa, Castaneda, Santos, Martin, Javier, Gonzalez-Escribano, Maria Francisca, Barnosi-Marin, Ana Celia, Gonzalez-Gay, Miguel Angel, Grana-Gil, Genaro et al.
DOI: 10.1371/journal.pone.0102100

Criterion and concurrent validity of Conners Adult ADHD Diagnostic Interview for DSM-IV (CAADID) Spanish version.

PMID: 23021295
Journal: Revista de psiquiatria y salud mental
Year: 2012
Reference: Rev Psiquiatr Salud Ment. 2012 Oct-Dec;5(4):229-35. doi: 10.1016/j.rpsm.2012.05.004. Epub 2012 Jul 4.
Impact factor: 0.308
Publication type: Paper in national publication
Authors: Vidal, Raquel, Chalita, Pablo J, Casas, Miguel, Real, Alberto, Corominas, Margarida, Corrales, Montse, Ramos-Quiroga, Josep Antoni, Bosch, Rosa, Richarte, Vanesa, Valero, Sergi et al.
DOI: 10.1016/j.rpsm.2012.05.004

Anti-ganglioside antibodies in patients with systemic lupus erythematosus and neurological manifestations.

PMID: 22323340
Journal: LUPUS
Year: 2012
Reference: Lupus. 2012 May;21(6):611-5. Epub 2012 Feb 9.
Impact factor: 2.337
Publication type: Paper in international publication
Authors: Labrador-Horrillo, M, Martinez-Valle, F, Gallardo, E, Rojas-Garcia, R, Ordi-Ros, J, Vilardell, M et al.
DOI: 10.1177/0961203312436856

Autoimmune/inflammatory syndrome (ASIA) induced by biomaterials injection other than silicone medical grade.

PMID: 22952322
Journal: LUPUS
Year: 2012
Reference: Lupus. 2012;21(12):1326-34. Epub 2012 Sep 5.
Impact factor: 2.337
Publication type: Paper in international publication
Authors: Alijotas-Reig, J, Garcia-Gimenez, V, Llurba, E, Vilardell-Tarres, M, , et al.
DOI: 10.1177/0961203312458838

Screening for the presence of FMR1 premutation alleles in a Spanish population with fibromyalgia.

PMID: 22903700
Journal: CLINICAL RHEUMATOLOGY
Year: 2012
Reference: Clin Rheumatol. 2012 Nov;31(11):1611-5. doi: 10.1007/s10067-012-2052-y. Epub 2012 Aug 18.
Impact factor: 1.996
Publication type: Paper in international publication
Authors: Naudo, Montserrat, Martorell, Loreto, Tondo, Mireia, Garcia-Fructuoso, Ferran, Genoves, Jordi, Poo, Pilar, Gamez, Josep, Alegre, Cayetano et al.
DOI: 10.1007/s10067-012-2052-y

Is obstetric antiphospholipid syndrome a primary nonthrombotic, proinflammatory, complement-mediated disorder related to antiphospholipid antibodies?

PMID: 20040128
Journal: OBSTETRICAL & GYNECOLOGICAL SURVEY
Year: 2010
Reference: Obstet Gynecol Surv. 2010 Jan;65(1):39-45.
Impact factor: 3.097
Publication type: Paper in international publication
Authors: Alijotas-Reig, Jaume, Vilardell-Tarres, Miquel, Alijotas Reig, Jaume et al.
DOI: 10.1097/OGX.0b013e3181c97809

Echocardiography at diagnosis of antiphospholipid syndrome provides prognostic information on valvular disease evolution and identifies two subtypes of patients.

PMID: 20068017
Journal: LUPUS
Year: 2010
Reference: Lupus. 2010;19(5):575-82. Epub 2010 Jan 12.
Impact factor: 2.586
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1177/0961203309353772

Cancer-associated myositis and anti-p155 autoantibody in a series of 85 patients with idiopathic inflammatory myopathy.

PMID: 20075704
Journal: MEDICINE
Year: 2010
Reference: Medicine (Baltimore). 2010 Jan;89(1):47-52.
Impact factor: 5.054
Publication type: Paper in international publication
Authors: Trallero-Araguas, Ernesto, Labrador-Horrillo, Moises, Selva-O'Callaghan, Albert, Martinez, Maria Angeles, Martinez-Gomez, Xavier, Palou, Eduard, Rodriguez-Sanchez, Jose Luis, Vilardell-Tarres, Miquel et al.
DOI: 10.1097/MD.0b013e3181ca14ff

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The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.