About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 35576644 Journal: EBioMedicine Year: 2022 Reference: EBioMedicine. 2022 Jun;80:104053. doi: 10.1016/j.ebiom.2022.104053. Epub 2022 May 13. Impact factor: 8.143 Publication type: Paper in international publication Authors: Julia, Antonio, Gomez, Antonio, Lopez-Lasanta, Maria, Blanco, Francisco, Erra, Alba, Fernandez-Nebro, Antonio, Mas, Antonio Juan, Perez-Garcia, Carolina, Vivar, Ma Luz Garcia, Sanchez-Fernandez, Simon et al. DOI: 10.1016/j.ebiom.2022.104053
PMID: 35567393 Journal: ALLERGY Year: 2022 Reference: Allergy. 2022 May 14. doi: 10.1111/all.15371. Impact factor: 13.146 Publication type: Paper in international publication Authors: Bedbrook, Anna, Sousa-Pinto, Bernardo, Schunemann, Holger J, Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Anto, Josep M, Klimek, Ludger, Czarlewski, Wienczyslawa, Mullol, Joaquim et al. DOI: 10.1111/all.15371
PMID: 34538611 Journal: Reumatologia clinica Year: 2022 Reference: Reumatol Clin. 2022 May;18(5):260-265. doi: 10.1016/j.reumae.2021.01.005. Epub 2021 Sep 15. Impact factor: 0 Publication type: Paper in national publication Authors: Trillo Calvo, Eva, Rivera Redondo, Javier, Diaz Del Campo Fontecha, Petra, Alegre de Miquel, Cayetano, Almirall Bernabe, Miriam, Casanueva Fernandez, Benigno, Castillo Ojeda, Cristina, Collado Cruz, Antonio, Monteso-Curto, Pilar, Palao Tarrero, Angela et al. DOI: 10.1016/j.reuma.2021.01.006
PMID: 35536413 Journal: CLINICAL RHEUMATOLOGY Year: 2022 Reference: Clin Rheumatol. 2022 Aug;41(8):2361-2373. doi: 10.1007/s10067-022-06176-1. Epub 2022 May 10. Impact factor: 2.98 Publication type: Paper in international publication Authors: Patel, Yusuf, Marsal, Sara, Sanmarti, Raimon, Nurmohamed, Michael T, Griffiths, Hedley, Peichl, Peter, Bannert, Bettina, Chartier, Melanie, Connolly, Sean E, Lozenski, Karissa et al. DOI: 10.1007/s10067-022-06176-1
PMID: 33426389 Journal: Kidney International Reports Year: 2021 Reference: Kidney Int Rep. 2020 Oct 12;6(1):101-109. doi: 10.1016/j.ekir.2020.09.046. eCollection 2021 Jan. Impact factor: Publication type: Paper in international publication Authors: Jatem, Elias; Lima, Joan; Montoro, Bruno; Segarra, Alfons; Torres-Bondia, Francisco et al. DOI: 10.1016/j.ekir.2020.09.046
PMID: 32512619 Journal: ALLERGY Year: 2021 Reference: Allergy. 2021 Jan;76(1):168-190. doi: 10.1111/all.14422. Epub 2020 Oct 23. Impact factor: Publication type: Review in international publication Authors: Agache, Ioana; Akdis, Cezmi A; Almeida, Rute; Annesi-Maesano, Isabella; Ansotegui, Ignacio J; Anto, Josep M; Arnavielhe, Sylvie; Bachert, Claus; Basagana, Xavier; Bateman, Eric et al. DOI: 10.1111/all.14422
PMID: 32658963 Journal: RHEUMATOLOGY Year: 2021 Reference: Rheumatology (Oxford). 2021 Jan 5;60(1):217-223. doi: 10.1093/rheumatology/keaa247. Impact factor: Publication type: Paper in international publication Authors: Carballo, Iago; de Miguel-Campo, Borja; Feijoo-Masso, Carlos; Fernandez-Codina, Andreu; Fonseca-Aizpuru, Eva; Hernandez-Rodriguez, Jose; Lopez-Dupla, Miguel; Martinez-Valle, Fernando; Pinal-Fernandez, Iago; Pinilla, Blanca et al. DOI: 10.1093/rheumatology/keaa247
PMID: 32183996 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia. 2021 Jan - Feb;36(1):92-94. doi: 10.1016/j.nrl.2020.02.001. Epub 2020 Mar 14. Impact factor: Publication type: Letter or abstract Authors: Hernandez-Vara, J; Lucas-Del-Pozo, S; Moreno-Martinez, D; Tejero-Ambrosio, M et al. DOI: 10.1016/j.nrl.2020.02.001
PMID: 32740086 Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY Year: 2020 Reference: Am J Gastroenterol. 2020 Dec;115(12):2047-2059. doi: 10.14309/ajg.0000000000000789. Impact factor: 10.171 Publication type: Paper in international publication Authors: Guilarte, Mar, Vicario, Maria, Martinez, Cristina, de Torres, Ines, Lobo, Beatriz, Pigrau, Marc, Gonzalez-Castro, Ana, Rodino-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina et al. DOI: 10.14309/ajg.0000000000000789
PMID: 32735720 Journal: CLINICAL AND EXPERIMENTAL ALLERGY Year: 2020 Reference: Clin Exp Allergy. 2020 Oct;50(10):1166-1175. doi: 10.1111/cea.13716. Epub 2020 Sep 3. Impact factor: 4.217 Publication type: Paper in international publication Authors: Chapman-Rothe, N, Maurer, M, Costa, C, Gimenez Arnau, A, Guillet, G, Labrador-Horrillo, M, Lapeere, H, Meshkova, R, Savic, S et al. DOI: 10.1111/cea.13716
PMID: 32716834 Journal: European journal of rheumatology Year: 2020 Reference: Eur J Rheumatol. 2020 Jul 21. pii: eurjrheum.2020.20038. doi: 10.5152/eurjrheum.2020.20038. Impact factor: 0 Publication type: Paper in international publication Authors: Coras, Roxana, Sturchio, Gustavo Anez, Bru, Mireia Barcelo, Fernandez, Agusti Sellas, Farietta, Sandra, Badia, Salvador Campos, Diez, Basilio Rodriguez, de Agustin de Oro, Juan Jose et al. DOI: 10.5152/eurjrheum.2020.20038
PMID: 32659758 Journal: DERMATOLOGY Year: 2020 Reference: Dermatology. 2020;236(5):467-476. doi: 10.1159/000508672. Epub 2020 Jul 13. Impact factor: 3.695 Publication type: Review in international publication Authors: Domingo, Sandra, Sole, Cristina, Moline, Teresa, Ferrer, Berta, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al. DOI: 10.1159/000508672
PMID: 31672989 Journal: Nature Communications Year: 2019 Reference: Nat Commun. 2019 Oct 31;10(1):4955. doi: 10.1038/s41467-019-12760-y. Impact factor: 11.878 Publication type: Paper in international publication Authors: Rios, R, de Vries-Bouwstra, Jeska, Wijmenga, Cisca, Koeleman, Bobby P C, Nordin, Annika, Padyukov, Leonid, Hoffmann-Vold, Anna-Maria, Lie, Benedicte, Proudman, Susanna, Stevens, Wendy et al. DOI: 10.1038/s41467-019-12760-y
PMID: 31656683 Journal: Journal of Thoracic Disease Year: 2019 Reference: J Thorac Dis. 2019 Sep;11(9):4072-4084. doi: 10.21037/jtd.2019.09.38. Impact factor: 2.027 Publication type: Review in international publication Authors: Williams, Sian, Pham-Thi, Nhan, Bedbrook, Anna, Agache, Ioana, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep M, Bachert, Claus, Benveniste, Samuel, Bewick, Mike et al. DOI: 10.21037/jtd.2019.09.38
PMID: 31635909 Journal: NEUROMUSCULAR DISORDERS Year: 2019 Reference: Neuromuscul Disord. 2019 Nov;29(11):819-825. doi: 10.1016/j.nmd.2019.09.014. Epub 2019 Sep 26. Impact factor: 2.612 Publication type: Review in international publication Authors: Selva-O'Callaghan, Albert, Ros, Javier, Gil-Vila, Albert, Vila-Pijoan, Gemma, Trallero-Araguas, Ernesto, Pinal-Fernandez, Iago et al. DOI: 10.1016/j.nmd.2019.09.014
PMID: 31639024 Journal: Orphanet Journal of Rare Diseases Year: 2019 Reference: Orphanet J Rare Dis. 2019 Oct 21;14(1):230. doi: 10.1186/s13023-019-1202-6. Impact factor: 3.687 Publication type: Paper in international publication Authors: Sampayo-Cordero, Miguel, Miguel-Huguet, Bernat, Pardo-Mateos, Almudena, Malfettone, Andrea, Perez-Garcia, Jose, Llombart-Cussac, Antonio, Cortes, Javier, Molto-Abad, Marc, Munoz-Delgado, Cecilia, Perez-Quintana, Marta et al. DOI: 10.1186/s13023-019-1202-6
PMID: 29965856 Journal: CURRENT OPINION IN RHEUMATOLOGY Year: 2018 Reference: Curr Opin Rheumatol. 2018 Nov;30(6):630-636. doi: 10.1097/BOR.0000000000000535. Impact factor: 4.277 Publication type: Paper in international publication Authors: Selva-O'Callaghan, Albert, Martinez-Gomez, Xavier, Trallero-Araguas, Ernesto, Pinal-Fernandez, Iago et al. DOI: 10.1097/BOR.0000000000000535
PMID: 29241876 Journal: MEDICINA CLINICA Year: 2018 Reference: Med Clin (Barc). 2018 Jul 13;151(1):18-25. doi: 10.1016/j.medcli.2017.10.034. Epub 2017 Dec 11. Impact factor: 1.168 Publication type: Review in national publication Authors: Martinez-Valle, Fernando, Orozco-Galvez, Olimpia, Fernandez-Codina, Andreu et al. DOI: 10.1016/j.medcli.2017.10.034
PMID: 29930757 Journal: Oncotarget Year: 2018 Reference: Oncotarget. 2018 Jun 5;9(43):27151-27170. doi: 10.18632/oncotarget.25502. eCollection 2018 Jun 5. Impact factor: 0 Publication type: Paper in international publication Authors: Tusell, Laura, Dominguez, Daniel, Bernal, Aina, Molto-Abad, Marc et al. DOI: 10.18632/oncotarget.25502
PMID: 29931516 Journal: CLINICAL RHEUMATOLOGY Year: 2018 Reference: Clin Rheumatol. 2018 Aug;37(8):2303-2304. doi: 10.1007/s10067-018-4179-y. Impact factor: 2.141 Publication type: Letter or abstract Authors: Callejas Moraga, E, Calvo, E, Carbonell, C, Castillo, M J, Chamorro, A J, Colunga, D, Corbella, X, Egurbide, M V, Espinosa, G, Fonollosa, V et al. DOI: 10.1007/s10067-018-4179-y
PMID: 27486035 Journal: Gaceta Sanitaria Year: 2017 Reference: Gac Sanit. 2017 Jul - Aug;31(4):327-331. doi: 10.1016/j.gaceta.2016.06.013. Epub 2016 Jul 30. Impact factor: 1.509 Publication type: Paper in national publication Authors: Lopez-Soto, Alfonso, Torres, Olga H, San-Jose, Antonio, Formiga, Francesc, Vidal, Xavier, Garcia, Juana, Rivas-Cobas, Paula Carlota, Ramirez-Duque, Nieves, Gomez Hernandez, Mercedes, Agusti, Antonia et al. DOI: 10.1016/j.gaceta.2016.06.013
PMID: 29214141 Journal: Allergo journal international Year: 2017 Reference: Allergo J Int. 2017;26(8):295-300. doi: 10.1007/s40629-017-0042-y. Epub 2017 Nov 15. Impact factor: 0 Publication type: Review in national publication Authors: Worm, Margitta, Sturm, Gunter, Kleine-Tebbe, Jorg, Cichocka-Jarosz, Ewa, Cardona, Victoria, Maris, Ioana, Dolle, Sabine et al. DOI: 10.1007/s40629-017-0042-y
PMID: 29177080 Journal: RMD open Year: 2017 Reference: RMD Open. 2017 Nov 14;3(2):e000507. doi: 10.1136/rmdopen-2017-000507. eCollection 2017. Impact factor: 0 Publication type: Paper in international publication Authors: Danko, Katalin, Dimachkie, Mazen M, Feldman, Brian M, Garcia-De La Torre, Ignacio, Gordon, Patrick, Hayashi, Taichi, Katz, James D, Kohsaka, Hitoshi, Lachenbruch, Peter A, Lang, Bianca A et al. DOI: 10.1136/rmdopen-2017-000507
PMID: 29106061 Journal: Arthritis & Rheumatology Year: 2017 Reference: Arthritis Rheumatol. 2017 Dec;69(12):2271-2282. doi: 10.1002/art.40320. Epub 2017 Oct 27. Impact factor: 6.918 Publication type: Paper in international publication Authors: Bottai, Matteo, Lundberg, Ingrid E, Tjarnlund, Anna, Sanner, Helga, Selva-O'Callaghan, Albert, Song, Yeong-Wook, Vencovsky, Jiri, Ytterberg, Steven R, Miller, Frederick W, Rider, Lisa G et al. DOI: 10.1002/art.40320
PMID: 26333026 Journal: DIABETIC MEDICINE Year: 2016 Reference: Diabet Med. 2016 May;33(5):655-62. doi: 10.1111/dme.12894. Epub 2015 Oct 18. Impact factor: 3.152 Publication type: Paper in international publication Authors: Formiga, F, Vidal, X, Agusti, A, Chivite, D, Roson, B, Ponte, Paola, Ortiz, Gabriel, Cobas, Paula-Carlota Rivas, Gil, Paloma, Turbau, Miquel et al. DOI: 10.1111/dme.12894
PMID: 27938773 Journal: CHEST Year: 2016 Reference: Chest. 2016 Dec;150(6):e159-e165. doi: 10.1016/j.chest.2016.08.1449. Impact factor: 5.94 Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu, Aranda-Rodriguez, Santiago, Romagosa, Cleofe, Deu-Martin, Maria, Parra-Farinas, Carmen, Bujan-Rivas, Segundo et al. DOI: 10.1016/j.chest.2016.08.1449
PMID: 27716427 Journal: ARTHRITIS RESEARCH & THERAPY Year: 2016 Reference: Arthritis Res Ther. 2016 Oct 4;18(1):221. Impact factor: 3.979 Publication type: Paper in international publication Authors: Torices, Silvia, Julia, Antonio, Munoz, Pedro, Varela, Ignacio, Balsa, Alejandro, Marsal, Sara, Fernandez-Nebro, Antonio, Blanco, Francisco, Lopez-Hoyos, Marcos, Martinez-Taboada, Victor et al. DOI: 10.1186/s13075-016-1113-z
PMID: 27640317 Journal: AUTOIMMUNITY REVIEWS Year: 2016 Reference: Autoimmun Rev. 2016 Dec;15(12):1161-1166. doi: 10.1016/j.autrev.2016.09.005. Epub 2016 Sep 15. Impact factor: 8.49 Publication type: Paper in international publication Authors: Selva-O'Callaghan, A, Pujol-Borrell, R, Alvarado-Cardenas, M, Marin, A, Martinez, M A, Pinal-Fernandez, I, Labrador-Horrillo, M, Balada, E, Mundet-Tuduri, X, Gonzalez-Mera, L et al. DOI: 10.1016/j.autrev.2016.09.005
PMID: 26423784 Journal: LUNG Year: 2015 Reference: Lung. 2015 Dec;193(6):993-1000. doi: 10.1007/s00408-015-9807-6. Epub 2015 Sep 30. Impact factor: 2.271 Publication type: Paper in international publication Authors: Martinez-Sogues, Mireia, Lopez, Iker, Pallisa, Esther, Schoenenberger, Joan Antoni, Bruno Montoro, J, de Sevilla, Tomas Fernandez, Sune, Pilar, Deu, Maria, Bielsa, Silvia, Aleman, Carmen et al. DOI: 10.1007/s00408-015-9807-6
PMID: 25798438 Journal: Annals of Animal Science Year: 2015 Reference: Front Bioeng Biotechnol. 2015 Mar 5;3:23. doi: 10.3389/fbioe.2015.00023. eCollection 2015. Impact factor: 0.613 Publication type: Review in national publication Authors: Alonso, Arnald, Marsal, Sara, Julia, Antonio et al. DOI: 10.3389/fbioe.2015.00023
PMID: 26051464 Journal: Reumatologia clinica Year: 2015 Reference: Reumatol Clin. 2015 Sep-Oct;11(5):279-294. doi: 10.1016/j.reuma.2015.05.001. Epub 2015 Jun 6. Impact factor: 0 Publication type: Paper in international publication Authors: Sanmarti, Raimon, Garcia-Rodriguez, Susana, Alvaro-Gracia, Jose Maria, Andreu, Jose Luis, Balsa, Alejandro, Caliz, Rafael, Fernandez-Nebro, Antonio, Ferraz-Amaro, Ivan, Gomez-Reino, Juan Jesus, Gonzalez-Alvaro, Isidoro et al. DOI: 10.1016/j.reuma.2015.05.001
PMID: 25990289 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2015 Reference: Ann Rheum Dis. 2015 Oct;74(10):1875-81. doi: 10.1136/annrheumdis-2014-207190. Epub 2015 May 19. Impact factor: 10.377 Publication type: Paper in international publication Authors: Canete, Juan D, Rubio, Esteban, Salvador, Georgina, Diaz-Torne, Cesar, Blanco, Ricardo, Willisch Dominguez, Alfredo, Mosquera, Jose Antonio, Vela, Paloma, Tornero, Jesus, Sanchez-Fernandez, Simon et al. DOI: 10.1136/annrheumdis-2014-207190
PMID: 25409453 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Nov 19;9(11):e113476. doi: 10.1371/journal.pone.0113476. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Marquez, Ana, Solans, Roser, Hernandez-Rodriguez, Jose, Cid, Maria C, Castaneda, Santos, Ramentol, Marc, Rodriguez-Rodriguez, Luis, Narvaez, Javier, Blanco, Ricardo, Ortego-Centeno, Norberto et al. DOI: 10.1371/journal.pone.0113476
PMID: 24215577 Journal: ALLERGY Year: 2014 Reference: Allergy. 2014 Feb;69(2):159-67. doi: 10.1111/all.12314. Epub 2013 Nov 12. Impact factor: 5.995 Publication type: Review in national publication Authors: Akdis, C A, de Silva, D, Geromi, M, Panesar, S S, Muraro, A, Werfel, T, Hoffmann-Sommergruber, K, Roberts, G, Cardona, V, Dubois, A E J et al. DOI: 10.1111/all.12314
PMID: 24205824 Journal: ALLERGY Year: 2014 Reference: Allergy. 2014 Jan;69(1):62-75. doi: 10.1111/all.12305. Epub 2013 Nov 11. Impact factor: 5.995 Publication type: Review in national publication Authors: Sheikh, A, Vlieg-Boerstra, B J, Roberts, G, Nwaru, B I, Hickstein, L, Panesar, S S, Muraro, A, Werfel, T, Cardona, V, Dubois, A E J et al. DOI: 10.1111/all.12305
PMID: 24251536 Journal: ALLERGY Year: 2014 Reference: Allergy. 2014 Feb;69(2):168-75. doi: 10.1111/all.12318. Epub 2013 Nov 20. Impact factor: 5.995 Publication type: Review in international publication Authors: Dhami, S, Papadopoulos, N, Hoffman-Sommergruber, K, Poulsen, L, Timmermans, F, Van Ree, R, Jutel, M, Harada, L, Demoly, P, Clark, A et al. DOI: 10.1111/all.12318
PMID: 22886951 Journal: GENETIC EPIDEMIOLOGY Year: 2012 Reference: Genet Epidemiol. 2012 Nov;36(7):710-6. doi: 10.1002/gepi.21665. Epub 2012 Aug 7. Impact factor: 3.441 Publication type: Paper in international publication Authors: Julia, Antonio, Gelpi, Josep Lluis, Marsal, Sara, Canela-Xandri, Oriol et al. DOI: 10.1002/gepi.21665
PMID: 22845005 Journal: ALLERGY Year: 2012 Reference: Allergy. 2012 Oct;67(10):1316-8. doi: 10.1111/j.1398-9995.2012.02877.x.. Epub 2012 Jul 30. Impact factor: 6.271 Publication type: Paper in international publication Authors: Sala-Cunill, A, Cardona, V, Luengo, O, Garriga, T, Labrador-Horrillo, M, Guilarte, M, Soto, L, Izquierdo, A et al. DOI: 10.1111/j.1398-9995.2012.02877.x.
PMID: 22844327 Journal: Clinical & Developmental Immunology Year: 2012 Reference: Clin Dev Immunol. 2012;2012:926931. Epub 2012 Jul 16. Impact factor: 1.838 Publication type: Editorail in international publication Authors: Fernandez-Nebro, Antonio, Marsal, Sara, Chatham, Winn, Rahman, Anisur et al. DOI: 10.1155/2012/926931
PMID: 22817696 Journal: Health and Quality of Life Outcomes Year: 2012 Reference: Health Qual Life Outcomes. 2012 Jul 20;10:82. doi: 10.1186/1477-7525-10-82. Impact factor: 2.112 Publication type: Paper in international publication Authors: Prior, Nieves, Remor, Eduardo, Gomez-Traseira, Carmen, Lopez Serrano, Concepcion, Cabanas, Rosario, Contreras, Javier, Campos, Angel, Cardona, Victoria, Cimbollek, Stefan, Gonzalez-Quevedo, Teresa et al. DOI: 10.1186/1477-7525-10-82
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
