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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Publications

Efficacy and Safety of PCSK9 Inhibitors in Hypercholesterolemia Associated With Refractory Nephrotic Syndrome.

PMID: 33426389
Journal: Kidney International Reports
Year: 2021
Reference: Kidney Int Rep. 2020 Oct 12;6(1):101-109. doi: 10.1016/j.ekir.2020.09.046. eCollection 2021 Jan.
Impact factor: 4.164
Publication type: Paper in international publication
Authors: Jatem, Elias, Lima, Joan, Montoro, Bruno, Torres-Bondia, Francisco, Segarra, Alfons et al.
DOI: 10.1016/j.ekir.2020.09.046

ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.

PMID: 32512619
Journal: ALLERGY
Year: 2021
Reference: Allergy. 2021 Jan;76(1):168-190. doi: 10.1111/all.14422. Epub 2020 Oct 23.
Impact factor: 13.146
Publication type: Review in international publication
Authors: Bouchard, Jacques, Bousquet, Jean, Anto, Josep M, Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G et al.
DOI: 10.1111/all.14422

Performance of the 2019 ACR/EULAR classification criteria for IgG4-related disease and clinical phenotypes in a Spanish multicentre registry (REERIGG4).

PMID: 32658963
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Jan 5;60(1):217-223. doi: 10.1093/rheumatology/keaa247.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Pinilla, Blanca, Fernandez-Codina, Andreu, Feijoo-Masso, Carlos, Toledano-Macias, Maria, de Miguel-Campo, Borja, Fonseca-Aizpuru, Eva, Saez-Comet, Luis, Lopez-Dupla, Miguel, Hernandez-Rodriguez, Jose, Martinez-Valle, Fernando et al.
DOI: 10.1093/rheumatology/keaa247

MicroRNA expression profiling identifies miR-31 and miR-485-3p as regulators in the pathogenesis of Discoid Cutaneous Lupus.

PMID: 30130620
Journal: JOURNAL OF INVESTIGATIVE DERMATOLOGY
Year: 2019
Reference: J Invest Dermatol. 2019 Jan;139(1):51-61. doi: 10.1016/j.jid.2018.07.026. Epub 2018 Aug 18.
Impact factor: 6.29
Publication type: Paper in international publication
Authors: Sole, Cristina, Domingo, Sandra, Ferrer, Berta, Moline, Teresa, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al.
DOI: 10.1016/j.jid.2018.07.026

Blog

News

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.

The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.