Vés al contingut

Recerca Biomèdica en Ginecologia

El Grup de Recerca Biomèdica en Ginecologia (GBR-G) és un equip multidisciplinari format per clínics especialistes en ginecologia i patologia, i investigadors bàsics i translacionals. La nostra recerca és clarament translacional. Tot i que tenim en compte la importància òbvia de comprendre el mecanisme a nivell cel·lular i molecular i intentem incorporar-lo a la nostra recerca. La nostra recerca sempre està enfocada a tenir una aplicabilitat directa als pacients i el seu benefici clínic. En el nostre camí per transferir resultats científics a la clínica, fomentem la innovació i l'emprenedoria.

El nostre grup està format per quatre subgrups de recerca, que estan estretament connectats: el grup de recerca clínica dedicat principalment a projectes clínics en tots els càncers ginecològics; i tres grups de recerca translacional dedicats al càncer d'ovari; el càncer d'endometri i endometriosi; i les malalties del tracte genital femení baix.

Equip

Antonio Gil Moreno

Antonio Gil Moreno

Cap de grup
Recerca biomèdica en ginecologia
Llegir més
Eva Colas Ortega

Eva Colas Ortega

Cap de grup
Recerca biomèdica en ginecologia
Llegir més
Fco Javier De la Torre Fdez de Vega

Fco Javier De la Torre Fdez de Vega

Investigador/a sènior
Recerca biomèdica en ginecologia
Llegir més
Laura Mañalich Barrachina

Laura Mañalich Barrachina

Investigador/a predoctoral
Recerca biomèdica en ginecologia
Llegir més
Maria Asuncion Perez Benavente

Maria Asuncion Perez Benavente

Investigador/a principal
Recerca biomèdica en ginecologia
Llegir més
Úrsula Acosta Sánchez

Úrsula Acosta Sánchez

Investigador/a principal
Recerca biomèdica en ginecologia
Llegir més
Antonio Gil Moreno

Antonio Gil Moreno

Cap de grup
Recerca biomèdica en ginecologia
Llegir més
Eva Colas Ortega

Eva Colas Ortega

Cap de grup
Recerca biomèdica en ginecologia
Llegir més
Fco Javier De la Torre Fdez de Vega

Fco Javier De la Torre Fdez de Vega

Investigador/a sènior
Recerca biomèdica en ginecologia
Llegir més
Laura Mañalich Barrachina

Laura Mañalich Barrachina

Investigador/a predoctoral
Recerca biomèdica en ginecologia
Llegir més
Maria Asuncion Perez Benavente

Maria Asuncion Perez Benavente

Investigador/a principal
Recerca biomèdica en ginecologia
Llegir més
Úrsula Acosta Sánchez

Úrsula Acosta Sánchez

Investigador/a principal
Recerca biomèdica en ginecologia
Llegir més

Línies de recerca

Clinical Research in Ginecology

Research team:


Dr. Antonio Gil-Moreno (Principal researcher)

Dr. Assumpció Pérez-Benavente (Clinical associated investigator)

Dr. José Lúís Sánchez Iglesias (Clinical associated investigator)

Dra. Silvia Cabrera (Clinical associated investigator)

Dr. Vicente Bebia Conesa (Clinical associated investigator)

Dr. Natalia Rodríguez Gómez-Hidalgo (Clinical associated investigator)

Dr. Javier de la Torre Fernández de Vega (Clinical associated investigator)

Dr. José Luís Poza Barrasús (Clinical associated investigator)

Dr. Sabina Salicrú Riera (Clinical associated investigator)

Dr. Laura Mañalich Barrachina (Clinical associated investigator)

Dr. Montse Cubo Albert (Clinical associated investigator)

Dr. Cristina Centeno Mediavilla (Clinical associated investigator)

Dr. Melissa Bradbury (Clinical associated investigator)

Dr. Sonia Monreal (Clinical associated investigator)

Dr. Angel García (Clinical associated investigator)

Dr. Armando Reques (Clinical associated investigator)

Dr. Elena Suárez (Clinical associated investigator)

Dr. Mireia Armengol (Clinical associated investigator/resident)

Dra. Eva Colás (Translational associated researcher)

Dr. Melek Denizli (Technician)



Research focus. Clinical Research Lines



CLINICAL ENDOMETRIAL CANCER RESEARCH

- Prospective, randomized study: STELLA1-2 Trial: Transperitoneal vs. Extraperitoneal Approach for Laparoscopic Staging of Endometrial/Ovarian Cancer. ClinicalTrials.gov Identifier: NCT01810874.

- Implementation of radioguided surgery for clinically occult lesions (ROLL) in abdominal recurrences of gynecological tumors.

- MULTISENT study: Ambiespective multicenter study of sentinel node biopsy in initial endometrial cancer.

- Concordance study between morphological techniques and OSNA (one-step nucleic cid amplification) for the detection of lymph node metastases in endometrial carcinoma.

- Preoperative staging of endometrial carcinoma by ultrasound 2D and 3D.


CLINICAL OVARIAN CANCER RESEARCH

- Prospective study: Postoperatory Recovery in Advanced Ovarian Cancer, Fast-Track Protocol vs. Classical Management (PROFAST). ClinicalTrials.gov Identifier: NCT02172638.

- EDMOCS study in ovarian cancer.

- SIMACEO study: Current Situation of the Management of Epithelial Cancer of the Ovary in initial stages in Spain.


CLINICAL CERVICAL CANCER RESEARCH

- Prospective study of validation of sentinel lymph node detection technique in early cervical cancer (FIGO 2018 stages IA2-IB1-IB2-IIA1).

- Collaborating center in the RACC Trial study (PI: Karolynska Hospital, Sweden): International, Prospective, Randomized comparative study of robotic versus laparotomic radical hysterectomy approach in early cervical cancer.

- Validation of robotic assisted and laparoscopic aortic extraperitoneal lymphadenectomy in recurrences of gynaecologic malignancies.

- Preoperative staging of carcinoma of the uterine cervix by ultrasound 2D and 3D.


CLINICAL RESEARCH IN BENIGN GYNECOLOGY

- Prospective study: Multicentric Comparative Randomized Study of the Single-incision Sling Ajust® Versus Suburethral Transobturator Slings. ClinicalTrials.gov Identifier: NCT01699425

- “A 3 Years Naturalistic Cohort Survey Of Altis® Single Incision Sling System For Female Stress Urinary Incontinence. A post-marketing and multicenter prospective observational cohort study in subjects with female stress urinary incontinence”.

- "Non-interventional study to evaluate quality of life, satisfaction with treatment, use of resources and persistence in treatment in patients with overactive bladder (OAB) who were prescribed Betmiga".

- “Comparative study of polyvinylidene fluoride and polypropylene suburethral-slings in the treatment of female stress urinary incontinence.”

- “Microarray analysis of differentially expressed genes in samples from patients with pelvic organ prolapse.”

Estudio EME: “Estudio epidemiológico sobre la miomatosis uterina en España”.


CLINICAL RESEARCH: MISCELLANEOUS

Prospective study of validation of sentinel lymph node detection technique in early vulvar cancer (early stages FIGO 2009)

- Prospective study of quality of life in patients with BRCA1-2 after risk-reducing adnexectomy.

- Prospective study of quality of life in patients with BRCA1-2 after risk-reducing mastectomy.

- Early detection of preneoplastic tubal lesions to delay ovarian cancer risk-reducing surgery in patients with BRCA1/2 mutations.

- Prospective, multicenter study for the evaluation of the intraoperative HPV test.

- INCIP Study: Cancer in pregnancy

- Randomized, open, multicentric, parallel group and control group clinical trial to evaluate the effect of PAPILOCARE® in the normalization of cytological alterations of the cervix caused by HPV (PALOMA II Clinical Trial).

- Cervical epithelium methylation as a risk marker of progression to HSIL in women with normal cytology and positive HPV.

- Conservative management of high-risk cervical intraepithelial lesions.

- Utility of DySIS® in the diagnosis and management of intraepithelial lesions of the lower genital tract.

- Breast Cancer During Pregnancy (BRCAPRE). ClinicalTrials.gov Identifier: NCT02102282.

IP: Antonio Gil Moreno

Endometrial Cancer and Endometriosis Research

Research team:


Dr. Eva Colas (Principal researcher)

Dr. Cristian Moiola (Post-doctoral researcher)

Dr. Eva Coll (PhD student)

Dr. Carlos López (PhD student)

Dr. Carina Masferrer (PhD student)

Dr. Beatriz Villafranca (PhD student)

Dr. Melek Denizli (Technician)

Dr. Marta Rebull (Technician)

Dr. Aida Soler (Technician)

Dr. Antonio Gil-Moreno (Principal researcher)

Dra. Silvia Cabrera (Clinical associated investigator)

Dr. Angel García (Clinical associated investigator)

Dr. Armando Reques (Clinical associated investigator)

Dra. Elena Suárez (Clinical associated investigator)

Dra. Mireia Armengol (Clinical associated investigator/resident)



Research focus


IMPLEMENTATION OF MOLECULAR DIAGNOSTICS IN ENDOMETRIAL CANCER

Early detection is directly related to an increased survival for endometrial cancer patients. Diagnosis of endometrial cancer initiates with the presence of symptoms, i.e. an abnormal vaginal bleeding, and 1 of every 10 women with this symptom will have an endometrial cancer. In order to improve early detection, we aim to improve the process of diagnosis by implementing molecular markers in proximal bodily fluids. Thus, we expect to minimize invasiveness whilst increase accuracy on the newly developed methods of diagnosis. In this research line, the group has two ongoing projects:

Proteomic biomarkers for an improved diagnosis in uterine aspirates.

Exploitation of pap-smears as an untapped source of biomarkers of endometrial cancer.


PREVENTING DISTANT AND LOCAL DISSEMINATION OF ENDOMETRIAL CANCER CELLS

Once a patient is diagnosed, the presence of prognostic factors are used to classify patients according to their risk of recurrence, which directly affects their clinical management. However, up to 20% of patients diagnosed at early stages, and up to 50% of patients diagnosed in advanced stages will suffer a relapse without means of predicting it. We aim to understand the mechanisms of local and distant tumour dissemination to develop strategies that prevent tumour relapse. Moreover, we aim to design tools to better estimate the risk of recurrence of endometrial cancer patients. In this research line, the group has two ongoing projects:

Understanding the molecular mechanisms associated to local and distant dissemination via studying the MELF component and the exosomes derived from the tumor.

Deciphering biomarkers of recurrence in endometrial cancer.


DEVELOPING INDIVIDUALIZED TREATMENT FOR ENDOMETRIAL CANCER PATIENTS

Nowadays, adjuvant treatment of metastatic or recurrent endometrial cancer patients is restricted to few therapeutic options, mostly based on radiotherapy and conventional chemotherapy regimens. Advances in understanding the molecular landscape of endometrial cancer have arisen the development of targeted therapies. However, responses to these targeted therapies are modest, probably due to the underestimation of the heterogeneity found in cancer, misrepresentation of low frequent subtypes of cancer, as well as the lack of clinically relevant models to perform pre-clinical studies, among other issues. The group aims to develop clinically relevant models and design experimental treatments in order to increase the response rate of patients. In this research line, the group has 2 ongoing projects:

The U-CAN platform of endometrial cancer PDX models to perform preclinical studies.

Identification of new experimental therapies.

Real-time oncology.


MOLECULAR DIAGNOSIS AND RECURRENCE PREDICTION IN ENDOMETRIOSIS

Endometriosis is an estrogen dependent disease that affects approximately 15% of women in reproductive age. Although endometriosis is considered a benign disease, characterized by the presence of uterine tissue outside the uterus, it causes strong pain and, often, infertility. So far, the gold standard method to diagnose endometriosis is laparoscopy, an invasive technique and there are no methods for early diagnose of the disease. In addition, patients undergoing surgery as a definitive treatment of endometriosis might recur without means of predicting it. In this research line, the group has 2 ongoing projects:

Assess the potential of angiogenic factors to diagnose and predict recurrence in endometriosis.

Identification of biomarkers to predict recurrence in endometrioma using a proteomic and transcriptomic approach.

IP: Eva Colas Ortega

Ovarian Cancer Research

Research team:


Dr. Melissa Bardbury (Principal researcher)

Dr. Antonio Gil-Moreno (Principal researcher)

Dra. Anna Santamaría (Stable collaborator)

Dr. Eva Coll (PhD student)

Dr. Carlos López (PhD student)

Dr. Melek Denizli (Technician)

Dr. José Luís Sánchez Iglesias (Clinical associated investigator)

Dr. Armando Reques (Clinical associated investigator)

Dr. Assumpció Pérez-Benavente (Clinical associated investigator)

Dr. Vicente Bebia Conesa (Clinical associated investigator)

Dr. Natalia Rodríguez Gómez-Hidalgo (Clinical associated investigator)

Dr. Javier de la Torre Fernández de Vega (Clinical associated investigator)


Research focus


PERIOPERATIVE IMMUNOMODULATION IN OVARIAN CANCER

Surgery for advanced ovarian cancer is a stressful stimulus that results in a pro-catabolic hormonal and cytokine environment, which significantly impacts metabolism. This metabolic response is accompanied by immune system impairment, increasing the risk of post-operative complications. In this research line the group is working in a multidisplinary project within the ERAS® program at the Vall d’Hebron Hospital for the: 

Identification of inflammatory markers predicting improved recovery after surgery within an ERAS® protocol.


MOLECULAR DIAGNOSTICS AND PREDICTION OF TREATMENT RESPONSE IN OVARIAN CANCER

Ovarian cancer remains the leading cause of death from gynecological malignancies due to its late diagnosis and high recurrence rates following treatment. There is a need to improve the early detection of the disease and identify predictive markers of treatment response. These diagnostic and predictive markers are being identified in proximal body fluids and patient-tissue samples. In this research line, the group has 3 ongoing projects:

Proteomic biomarkers for an improved diagnosis in uterine aspirates and pap-smears.

Proteomic biomarkers for the prediction of treatment response.

SalivOmiX: A salivary miRNA-based test for ovarian cancer early diagnosis.



IP: Melissa Bradbury Lobato, Antonio Gil Moreno

Preinvasive and invasive disease of the lower genital tract research

Research team:


Dr. Melissa Bradbury (Principal researcher)

Dr. Cristina Centeno (Clinical associated investigator)

Dr. Antonio Gil-Moreno (Principal researcher)

Dr. Carme Dinarés (Clinical associated investigator)

Dr. Josep Castellví (Clinical associated investigator)

Dr. Armando Reques (Clinical associated investigator)

Dr. Angel Garcia (Clinical associated investigator)

Dra. Eva Colás (Translational associated researcher)

Dr. Melek Denizli (Technician)


Research focus


NEW MARKERS FOR THE DIAGNOSIS AND PROGRESSION OF INTRAEPITHELIAL NEOPLASIA OF THE LOWER GENITAL TRACT

Persistent infections with high-risk human papillomavirus (HPV) genotypes are necessary, but not sufficient, cause of preinvasive and invasive lesions of the cervix and the lower genital tract. Although cancer screening prevention is based on HPV screening and pap-smear tests, it is essential to identify new molecular markers that can predict the transformation of HPV-associated lesions.

In this research line our group is assessing: Identification of molecular markers associated to an increased risk of development, persistence and progression of preinvasive lesions of the lower genital tract.





IP: Melissa Bradbury Lobato

Projectes

Approaching personalized treatment in endometrial cancer patients unveiling the intratumour heterogeneity

IP: Eva Colas Ortega
Col·laboradors: Beatriz Villafranca Magdalena, Miriam Izquierdo Sans
Entitat finançadora: Instituto de Salud Carlos III
Finançament: 19895
Referència: MV23/00016
Durada: 08/07/2024 - 20/12/2024

BIOBANCOS Y BIOMODELOS

IP: Isabel Novoa Garcia
Col·laboradors: Joaquim Vives Armengol, Anna Duarri Piqué, Eva Colas Ortega, Oriol Bestard Matamoros, Marta Rosal Fontana, Carmen Espejo Ruiz, Marielle Esteves Coelho, Juan Jose Gonzalez Lopez, Sheyla Pascual Martín, Alejandro Tomasello Weitz
Entitat finançadora: Instituto de Salud Carlos III
Finançament: 137460
Referència: PT23/00040
Durada: 01/01/2024 - 31/12/2026

Development of non-invasive molecular diagnosis of endometriosis

IP: Eva Colas Ortega
Col·laboradors: Raquel Delgado Gil, Miriam Izquierdo Sans
Entitat finançadora: Fundació Institut de Recerca HUVH
Finançament: 102820.06
Referència: VHIR-PHD-2023-005
Durada: 01/12/2023 - 30/11/2027

Desarrollo de CEMARK-Px, un método in vitro para el diagnóstico objetivo y preciso del tipo y grado histológico del cáncer de endometrio en fluido uterino

IP: Eva Colas Ortega
Col·laboradors: Vicente Bebia Conesa, Silvia Cabrera Diaz, Antonio Gil Moreno, Marta Rebull Santamaria, Ana Luzarraga Aznar, Irene De la Calle Fuentes, Melek Denizli, Lourdes Elena Salazar Huayna
Entitat finançadora: Instituto de Salud Carlos III
Finançament: 278300
Referència: DTS23/00091
Durada: 01/01/2024 - 31/12/2025

Publicacions

ESGO/ESTRO/ESP Guidelines for the management of patients with cervical cancer - Update 2023.

PMID: 37145263
Revista: VIRCHOWS ARCHIV
Any: 2023
Referència: Virchows Arch. 2023 May 5. doi: 10.1007/s00428-023-03552-3.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Bernabe, Sandra Rubio; Centeno, Carlos; Chargari, Cyrus; Cibula, David; Felix, Ana; Fischerova, Daniela; Jahnn-Kuch, Daniela; Joly, Florence; Kohler, Christhardt; Lax, Sigurd et al.
DOI: 10.1007/s00428-023-03552-3

Mortality and severe neurological morbidity in extremely preterm fetal growth-restricted fetuses.

PMID: 37325877
Revista: ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Any: 2023
Referència: Ultrasound Obstet Gynecol. 2023 Jun 16. doi: 10.1002/uog.26290.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Armengol-Alsina, M; Boada, D; Bonacina, E; Comas, M; De Diego, R; Figueras, F; Galindo, A; Gomez Roig, M D; Gonzalez, A; Herraiz, I et al.
DOI: 10.1002/uog.26290

ESGO/ESTRO/ESP Guidelines for the management of patients with cervical cancer - Update 2023.

PMID: 37336614
Revista: RADIOTHERAPY AND ONCOLOGY
Any: 2023
Referència: Radiother Oncol. 2023 Jul;184:109682. doi: 10.1016/j.radonc.2023.109682. Epub 2023 May 1.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Centeno, Carlos; Chargari, Cyrus; Cibula, David; Felix, Ana; Fischerova, Daniela; Jahnn-Kuch, Daniela; Joly, Florence; Kohler, Christhardt; Lax, Sigurd; Lindegaard, Jacob et al.
DOI: 10.1016/j.radonc.2023.109682

Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function.

PMID: 37587191
Revista: Communications Biology
Any: 2023
Referència: Commun Biol. 2023 Aug 16;6(1):780. doi: 10.1038/s42003-023-05070-z.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Andrews, Shan V; Becker, Christian; Collins, Frances; Ghukasyan, Zhanna; Giudice, Linda; Grosjean, Parker; Horne, Andrew W; Houshdaran, Sahar; Irwin, Juan C; Jacoby, Alison et al.
DOI: 10.1038/s42003-023-05070-z

Minimum standards of pelvic exenterative practice: PelvEx Collaborative guideline.

PMID: 36170347
Revista: British Journal of Surgery
Any: 2022
Referència: Br J Surg. 2022 Nov 22;109(12):1251-1263. doi: 10.1093/bjs/znac317.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Aalbers, A G J; Abdul Aziz, N; Abecasis, N; Abraham-Nordling, M; Akiyoshi, T; Alberda, W; Albert, M; Andric, M; Angeles, M A; Angenete, E et al.
DOI: 10.1093/bjs/znac317

Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.

PMID: 36328042
Revista: LANCET
Any: 2022
Referència: Lancet. 2022 Nov 5;400(10363):1607-1617. doi: 10.1016/S0140-6736(22)01846-3. Epub 2022 Oct 31.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: AAbdulrahmanlarood, Salameh A; Aaghar, Mohammad S; AAhmed, Abdelkareem; Aarabi, Shahram; Ab Rahman, Norhafiza; Ababneh, Hazim S; Abad-Motos, Ane; Abass, Khider Altayeb Bakheet; Abate, Emmanuele; Abayomi, Olukayode O et al.
DOI: 10.1016/S0140-6736(22)01846-3

Contemporary Management of Locally Advanced and Recurrent Rectal Cancer: Views from the PelvEx Collaborative.

PMID: 35267469
Revista: Cancers
Any: 2022
Referència: Cancers (Basel). 2022 Feb 24;14(5):1161. doi: 10.3390/cancers14051161.
Factor d'impacte:
Tipus de publicació: Revisió en revista internacional
Autors: Aalbers, A G J; Abdul Aziz, N; Abecasis, N; Abraham-Nordling, M; Abu Saadeh, F; Akiyoshi, T; Alberda, W; Albert, M; Andric, M; Angeles, M A et al.
DOI: 10.3390/cancers14051161

Uterine Inflammatory Myofibroblastic Neoplasms With Aggressive Behavior, Including an Epithelioid Inflammatory Myofibroblastic Sarcoma: A Clinicopathologic Study of 9 Cases.

PMID: 34138797
Revista: AMERICAN JOURNAL OF SURGICAL PATHOLOGY
Any: 2022
Referència: Am J Surg Pathol. 2022 Jan 1;46(1):105-117. doi: 10.1097/PAS.0000000000001756.
Factor d'impacte: 6.394
Tipus de publicació: Article en revista internacional
Autors: Collins, Katrina; Ramalingam, Preetha; Euscher, Elizabeth D; Reques Llanos, Armando; Garcia, Angel; Malpica, Anais et al.
DOI: 10.1097/PAS.0000000000001756

Endometrial Factor in Unexplained Infertility and Recurrent Implantation Failure.

PMID: 34425598
Revista:
Any: 2021
Referència: Semin Reprod Med. 2021 Nov;39(5-06):227-232. doi: 10.1055/s-0041-1735199. Epub 2021 Aug 23.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Santamaria, Xavier; Simon, Carlos et al.
DOI: 10.1055/s-0041-1735199

Value of Preoperative Use of Statins as a Protective Factor for Severe Graft Dysfunction After Lung Transplantation: A Multicenter Propensity Score Analysis.

PMID: 35699020
Revista: ARCHIVOS DE BRONCONEUMOLOGIA
Any: 2021
Referència: Arch Bronconeumol. 2021 Nov;57(11):720-722. doi: 10.1016/j.arbr.2021.04.015.
Factor d'impacte: 4.872
Tipus de publicació: Carta o abstract
Autors: Jauregui, Alberto, Pont, Teresa, Deu, Maria, Sacanell, Judith, Gomez, Aroa, Ussetti, Piedad, Crowley, Silvana, Minambres, Eduardo, Mora, Victor, Alvarez, Carlos et al.
DOI: 10.1016/j.arbr.2021.04.015

Retro cervical tunneling to ensure correct placement for robotic-assisted transabdominal cerclage.

PMID: 34579826
Revista: FERTILITY AND STERILITY
Any: 2021
Referència: Fertil Steril. 2021 Oct;116(4):1195-1196. doi: 10.1016/j.fertnstert.2021.08.021.
Factor d'impacte: 7.329
Tipus de publicació: Article en revista internacional
Autors: Suarez-Salvador, Elena, Goya, Maria, Acosta, Ursula, Vargas, Mireia, Bradbury, Melissa, Carreras, Elena, Gil-Moreno, Antonio et al.
DOI: 10.1016/j.fertnstert.2021.08.021

Recurrent superinfection in a patient with transjugular intrahepatic portosystemic shunt (endotipsitis), findings on (18)F-FDG PET/CT.

PMID: 34425974
Revista: Revista Espanola de Medicina Nuclear e Imagen Molecular
Any: 2021
Referència: Rev Esp Med Nucl Imagen Mol (Engl Ed). 2021 Sep-Oct;40(5):320-321. doi: 10.1016/j.remnie.2021.03.001. Epub 2021 Mar 11.
Factor d'impacte: 1.359
Tipus de publicació: Carta o abstract
Autors: Villasboas-Rosciolesi, D, Simo-Perdigo, M, Castell-Conesa, J, Aguade-Bruix, S et al.
DOI: 10.1016/j.remnie.2021.03.001

Preoperative risk stratification in endometrial cancer (ENDORISK) by a Bayesian network model: A development and validation study.

PMID: 32413043
Revista: PLOS MEDICINE
Any: 2020
Referència: PLoS Med. 2020 May 15;17(5):e1003111. doi: 10.1371/journal.pmed.1003111. eCollection 2020 May.
Factor d'impacte: 10.5
Tipus de publicació: Article en revista internacional
Autors: Reijnen, Casper, Gogou, Evangelia, Visser, Nicole C M, Engerud, Hilde, Pijnenborg, Johanna M A, Lucas, Peter J F, Kusters-Vandevelde, Heidi V N, Snijders, Marc P L M, Massuger, Leon F A G, Ramjith, Jordache et al.
DOI: 10.1371/journal.pmed.1003111

Prognostic Biomarkers in Endometrial Cancer: A Systematic Review and Meta-Analysis.

PMID: 32560580
Revista: Journal of Clinical Medicine
Any: 2020
Referència: J Clin Med. 2020 Jun 17;9(6). pii: jcm9061900. doi: 10.3390/jcm9061900.
Factor d'impacte: 3.303
Tipus de publicació: Revisió en revista internacional
Autors: Gil-Moreno, Antonio, Cabrera, Silvia, Colas, Eva, Dittmar, Gunnar, Martinez-Garcia, Elena, Coll-de la Rubia, Eva et al.
DOI: 10.3390/jcm9061900

Potential strategies for prevention of tumor spillage in minimally invasive radical hysterectomy.

PMID: 32808499
Revista: Journal of Gynecologic Oncology
Any: 2020
Referència: J Gynecol Oncol. 2020 Sep;31(5):e73. doi: 10.3802/jgo.2020.31.e73.
Factor d'impacte: 3.304
Tipus de publicació: Article en revista internacional
Autors: Bebia, Vicente, Monreal-Clua, Sonia, Perez-Benavente, Assumpcio, Franco-Camps, Silvia, Diaz-Feijoo, Berta, Gil-Moreno, Antonio et al.
DOI: 10.3802/jgo.2020.31.e73

Identification of early stage recurrence endometrial cancer biomarkers using bioinformatics tools.

PMID: 32705231
Revista: ONCOLOGY REPORTS
Any: 2020
Referència: Oncol Rep. 2020 Sep;44(3):873-886. doi: 10.3892/or.2020.7648. Epub 2020 Jun 16.
Factor d'impacte: 3.417
Tipus de publicació: Article en revista internacional
Autors: Argibay, Maria Cecilia, Abba, Martin, Furlong, Laura Ines, Colas, Eva, Gil-Moreno, Antonio, Reventos, Jaume, Bello, Ricardo, Vazquez-Levin, Monica Hebe, Lacunza, Ezequiel, Montivero, Luciana et al.
DOI: 10.3892/or.2020.7648

Characterization of the molecular changes associated with the overexpression of a novel epithelial cadherin splice variant mRNA in a breast cancer model using proteomics and bioinformatics approaches: identification of changes in cell metabolism and an increased expression of lactate dehydrogenase B.

PMID: 31086659
Revista: Cancer & Metabolism
Any: 2019
Referència: Cancer Metab. 2019 May 9;7:5. doi: 10.1186/s40170-019-0196-9. eCollection 2019.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Besso, Maria Jose; Canals, Francesc; Lapyckyj, Lara; Matos, Maria Laura; Monge, Marta; Quevedo Cuenca, Jorge Oswaldo; Reventos, Jaume; Rosso, Marina; Vazquez-Levin, Monica Hebe et al.
DOI: 10.1186/s40170-019-0196-9

Defining a mutational signature for endometrial cancer screening and early detection.

PMID: 31238232
Revista: Cancer Epidemiology
Any: 2019
Referència: Cancer Epidemiol. 2019 Aug;61:129-132. doi: 10.1016/j.canep.2019.06.003. Epub 2019 Jun 22.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Alemany, Laia; Aytes, Alvaro; Barahona, Marc; Benavente, Yolanda; Bianchi, Ilaria; Bosch, Francesc Xavier; Brunet, Joan; Capella, Gabriel; Climent, Maite; Costas, Laura et al.
DOI: 10.1016/j.canep.2019.06.003

New perspectives on screening and early detection of endometrial cancer.

PMID: 31199503
Revista: INTERNATIONAL JOURNAL OF CANCER
Any: 2019
Referència: Int J Cancer. 2019 Dec 15;145(12):3194-3206. doi: 10.1002/ijc.32514. Epub 2019 Jun 28.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Alemany, Laia; Aytes, Alvaro; Barahona, Marc; Benavente, Yolanda; Bianchi, Ilaria; Bosch, Francesc X; Brunet, Joan; Canet, Julia; Capella, Gabriel; Climent, Maite et al.
DOI: 10.1002/ijc.32514

FXYD5/Dysadherin, a Biomarker of Endometrial Cancer Myometrial Invasion and Aggressiveness: Its Relationship With TGF-beta1 and NF-kappaB Pathways.

PMID: 31867269
Revista: Frontiers in Oncology
Any: 2019
Referència: Front Oncol. 2019 Dec 6;9:1306. doi: 10.3389/fonc.2019.01306. eCollection 2019.
Factor d'impacte: 4.137
Tipus de publicació: Article en revista internacional
Autors: Besso, Maria Jose, Rosso, Marina, Lapyckyj, Lara, Moiola, Cristian Pablo, Matos, Maria Laura, Mercogliano, Maria Florencia, Schillaci, Roxana, Reventos, Jaume, Colas, Eva, Gil-Moreno, Antonio et al.
DOI: 10.3389/fonc.2019.01306

Laparoscopic Isthmocele Repair with Hysteroscopic Assistance.

PMID: 29032251
Revista: Journal of Minimally Invasive Gynecology
Any: 2018
Referència: J Minim Invasive Gynecol. 2018 May - Jun;25(4):576-577. doi: 10.1016/j.jmig.2017.10.005. Epub 2017 Oct 12.
Factor d'impacte: 3.061
Tipus de publicació: Article en revista internacional
Autors: Suarez Salvador, Elena, Haladjian, Cecilia, Bradbury, Melissa, Cubo-Abert, Montserrat, Manalich Barrachina, Laura, Vila Escude, Eva, Puig Puig, Oriol, Gil Moreno, Antonio et al.
DOI: 10.1016/j.jmig.2017.10.005

[Embolizing cardiac hibernoma and acute respiratory failure].

PMID: 30269781
Revista: Revista espanola de patologia : publicacion oficia
Any: 2018
Referència: Rev Esp Patol. 2018 Oct - Dec;51(4):267-270. doi: 10.1016/j.patol.2018.02.003. Epub 2018 Apr 5.
Factor d'impacte: 0
Tipus de publicació: Article en revista nacional
Autors: Montecino Romanini, Carolina, Reques Llanos, Armando, de Torres Ramirez, Ines, Rodriguez Morera, Jaime, Temprana Salvador, Jordi, Ramon Y Cajal, Santiago, Garcia Jimenez, Angel et al.
DOI: 10.1016/j.patol.2018.02.003

ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer.

PMID: 29682175
Revista: Oncotarget
Any: 2018
Referència: Oncotarget. 2018 Mar 30;9(24):16648-16664. doi: 10.18632/oncotarget.24625. eCollection 2018 Mar 30.
Factor d'impacte: 0
Tipus de publicació: Article en revista internacional
Autors: Devis, Laura, Martinez-Garcia, Elena, Moiola, Cristian P, Quiles, Maria Teresa, Arbos, Maria Antonia, Stirbat, Tomita Vasilica, Brochard-Wyart, Francoise, Garcia, Angel, Alonso-Alconada, Lorena, Abal, Miguel et al.
DOI: 10.18632/oncotarget.24625

Nerve Sparing Technique during Laparoscopic Radical Hysterectomy: Critical Steps.

PMID: 29432901
Revista: Journal of Minimally Invasive Gynecology
Any: 2018
Referència: J Minim Invasive Gynecol. 2018 Nov - Dec;25(7):1144-1145. doi: 10.1016/j.jmig.2018.01.034. Epub 2018 Feb 9.
Factor d'impacte: 3.061
Tipus de publicació: Article en revista internacional
Autors: Diaz-Feijoo, Berta, Bradbury, Melisa, Perez-Benavente, Assumpcio, Franco-Camps, Silvia, Gil-Moreno, Antonio et al.
DOI: 10.1016/j.jmig.2018.01.034

Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer.

PMID: 28055301
Revista: Autophagy
Any: 2017
Referència: Autophagy. 2017 Mar 4;13(3):608-624. doi: 10.1080/15548627.2016.1271512. Epub 2017 Jan 5.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Bergada, Laura; Boyd, Jeff; Chen, Bo-Juen; Dolcet, Xavier; Encinas, Mario; Eritja, Nuria; Gatius, Sonia; Llobet-Navas, David; Marti, Maria Dolores; Matias-Guiu, Xavier et al.
DOI: 10.1080/15548627.2016.1271512

Fluorescence spectroscopy and parallel factor analysis as a dissolved organic monitoring tool to assess treatment performance in drinking water trains.

PMID: 28169026
Revista: SCIENCE OF THE TOTAL ENVIRONMENT
Any: 2017
Referència: Sci Total Environ. 2017 Apr 15;584-585:1212-1220. doi: 10.1016/j.scitotenv.2017.01.184. Epub 2017 Feb 3.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Boleda, M R; Casas, S; Cortina, J L; Cruz, S; Gibert, O; Martin-Alonso, J; Mesa, J; Vera, M et al.
DOI: 10.1016/j.scitotenv.2017.01.184

Chromatin remodelling and DNA repair genes are frequently mutated in endometrioid endometrial carcinoma.

PMID: 27997699
Revista: INTERNATIONAL JOURNAL OF CANCER
Any: 2017
Referència: Int J Cancer. 2017 Apr 1;140(7):1551-1563. doi: 10.1002/ijc.30573. Epub 2017 Feb 2.
Factor d'impacte: 5.531
Tipus de publicació: Article en revista internacional
Autors: Garcia-Sanz, Pablo, Trivino, Juan Carlos, Mota, Alba, Perez Lopez, Maria, Colas, Eva, Rojo-Sebastian, Alejandro, Garcia, Angel, Gatius, Sonia, Ruiz, Maria, Prat, Jaime et al.
DOI: 10.1002/ijc.30573

Activated leukocyte cell adhesion molecule (ALCAM) is a marker of recurrence and promotes cell migration, invasion and metastasis in early stage endometrioid endometrial cancer.

PMID: 27873306
Revista: JOURNAL OF PATHOLOGY
Any: 2017
Referència: J Pathol. 2017 Mar;241(4):475-487. doi: 10.1002/path.4851. Epub 2017 Jan 23.
Factor d'impacte: 7.381
Tipus de publicació: Carta o abstract
Autors: Devis, Laura, Moiola, Cristian P, Masia, Nuria, Martinez-Garcia, Elena, Santacana, Maria, Stirbat, Tomita Vasilica, Brochard-Wyart, Francoise, Garcia, Angel, Alameda, Francesc, Cabrera, Silvia et al.
DOI: 10.1002/path.4851

Vulvar intraepithelial neoplasia: clinical presentation, management and outcomes in women infected with HIV.

PMID: 26959352
Revista: AIDS
Any: 2016
Referència: AIDS. 2016 Mar 27;30(6):859-68. doi: 10.1097/QAD.0000000000000984.
Factor d'impacte: 4.407
Tipus de publicació: Article en revista internacional
Autors: Bradbury, Melissa, Garcia-Jimenez, Angel, Franco-Camps, Silvia, Sanchez-Iglesias, Jose Luis, Diaz-Feijoo, Berta, Perez-Benavente, Assumpcio, Gil-Moreno, Antonio, Centeno-Mediavilla, Cristina, Cabrera, Silvia et al.
DOI: 10.1097/QAD.0000000000000984

Development of a sequential workflow based on LC-PRM for the verification of endometrial cancer protein biomarkers in uterine aspirate samples.

PMID: 27447978
Revista: Oncotarget
Any: 2016
Referència: Oncotarget. 2016 Aug 16;7(33):53102-53115. doi: 10.18632/oncotarget.10632.
Factor d'impacte: 5.008
Tipus de publicació: Article en revista internacional
Autors: Devis, Laura, Martinez-Garcia, Elena, Lesur, Antoine, van Oostrum, Jan, Matias-Guiu, Xavier, Gil-Moreno, Antonio, Reventos, Jaume, Colas, Eva, Domon, Bruno, Cabrera, Silvia et al.
DOI: 10.18632/oncotarget.10632

Exosome-like vesicles in uterine aspirates: a comparison of ultracentrifugation-based isolation protocols.

PMID: 27317346
Revista: Journal of Translational Medicine
Any: 2016
Referència: J Transl Med. 2016 Jun 18;14(1):180.
Factor d'impacte: 3.694
Tipus de publicació: Article en revista internacional
Autors: Campoy, Irene, Lanau, Lucia, Altadill, Tatiana, Sequeiros, Tamara, Cabrera, Silvia, Cubo-Abert, Montserrat, Perez-Benavente, Assumpcion, Garcia, Angel, Borros, Salvador, Santamaria, Anna et al.
DOI: 10.1186/s12967-016-0935-4

Enabling Metabolomics Based Biomarker Discovery Studies Using Molecular Phenotyping of Exosome-Like Vesicles.

PMID: 26974972
Revista: PLoS One
Any: 2016
Referència: PLoS One. 2016 Mar 14;11(3):e0151339. doi: 10.1371/journal.pone.0151339. eCollection 2016.
Factor d'impacte: 3.057
Tipus de publicació: Article en revista internacional
Autors: Altadill, Tatiana, Campoy, Irene, Lanau, Lucia, Gill, Kirandeep, Rigau, Marina, Gil-Moreno, Antonio, Reventos, Jaume, Byers, Stephen, Colas, Eva, Cheema, Amrita K et al.
DOI: 10.1371/journal.pone.0151339

Annexin-A2 as predictor biomarker of recurrent disease in endometrial cancer.

PMID: 25219463
Revista: INTERNATIONAL JOURNAL OF CANCER
Any: 2015
Referència: Int J Cancer. 2015 Apr 15;136(8):1863-73. doi: 10.1002/ijc.29213. Epub 2014 Sep 29.
Factor d'impacte: 5.085
Tipus de publicació: Article en revista internacional
Autors: Salvesen, Helga, Alonso-Alconada, Lorena, Santacana, Maria, Garcia-Sanz, Pablo, Muinelo-Romay, Laura, Colas, Eva, Mirantes, Cristina, Monge, Marta, Cueva, Juan, Oliva, Esther et al.
DOI: 10.1002/ijc.29213

Biological properties of extracellular vesicles and their physiological functions.

PMID: 25979354
Revista: Journal of Extracellular Vesicles
Any: 2015
Referència: J Extracell Vesicles. 2015 May 14;4:27066. doi: 10.3402/jev.v4.27066. eCollection 2015.
Factor d'impacte:
Tipus de publicació: Carta o abstract
Autors: Heegaard, Niels H H, Yanez-Mo, Maria, Siljander, Pia R-M, Andreu, Zoraida, Zavec, Apolonija Bedina, Borras, Francesc E, Buzas, Edit I, Buzas, Krisztina, Casal, Enriqueta, Cappello, Francesco et al.
DOI:

Simultaneous treatment with statins and aspirin reduces the risk of prostate cancer detection and tumorigenic properties in prostate cancer cell lines.

PMID: 25649906
Revista: Biomed Research International
Any: 2015
Referència: Biomed Res Int. 2015;2015:762178. doi: 10.1155/2015/762178. Epub 2015 Jan 12.
Factor d'impacte: 1.579
Tipus de publicació: Article en revista internacional
Autors: de Torres, I, Doll, A, Morote, J, Reventos, J, Placer, J, Planas, J, Celma, A, Olivan, M, Rigau, M, Colas, E et al.
DOI: 10.1155/2015/762178

Urinary biomarkers for the detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia.

PMID: 25845829
Revista: PROSTATE
Any: 2015
Referència: Prostate. 2015 Jul;75(10):1102-13. doi: 10.1002/pros.22995. Epub 2015 Apr 1.
Factor d'impacte: 3.565
Tipus de publicació: Article en revista internacional
Autors: Sequeiros, Tamara, Bastaros, Juan M, Sanchez, Milagros, Rigau, Marina, Montes, Melania, Placer, Jose, Planas, Jaques, de Torres, Ines, Reventos, Jaume, Pegtel, D Michiel et al.
DOI: 10.1002/pros.22995

Giant urinary bladder stone: incidental finding in (99m)Tc-DTPA renography.

PMID: 24686214
Revista: CLIN NUCL MED
Any: 2014
Referència: Clin Nucl Med. 2014 Jul;39(7):667-8. doi: 10.1097/RLU.0000000000000432.
Factor d'impacte: 2.857
Tipus de publicació: Carta o abstract
Autors: Garcia-Burillo, Amparo, Villasboas-Rosciolesi, Diego, Cardenas-Perilla, Rodrigo, Castell-Conesa, Joan et al.
DOI: 10.1097/RLU.0000000000000432

A 9-protein biomarker molecular signature for predicting histologic type in endometrial carcinoma by immunohistochemistry.

PMID: 25282036
Revista: HUM PATHOL
Any: 2014
Referència: Hum Pathol. 2014 Dec;45(12):2394-403. doi: 10.1016/j.humpath.2014.06.031. Epub 2014 Aug 23.
Factor d'impacte: 2.806
Tipus de publicació: Article en revista internacional
Autors: Santacana, Maria, Maiques, Oscar, Gatius, Sonia, Abo, Ana Isabel, Lopez-Garcia, Maria Angeles, Mota, Alba, Reventos, Jaume, Moreno-Bueno, Gema, Palacios, Jose, Bartosch, Carla et al.
DOI: 10.1016/j.humpath.2014.06.031

Role of p53 pathway alterations in uterine carcinosarcomas (malignant mixed Mullerian tumors).

PMID: 25033979
Revista: ONCOLOGY-BASEL
Any: 2014
Referència: Oncology. 2014;87(4):193-204. doi: 10.1159/000363574. Epub 2014 Jul 11.
Factor d'impacte: 2.613
Tipus de publicació: Revisió en revista nacional
Autors: Semczuk, Andrzej, Ignatov, Atanas, Obrzut, Bogdan, Reventos, Jaume, Rechberger, Tomasz et al.
DOI: 10.1159/000363574

Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer.

PMID: 25261936
Revista: MOL CANCER
Any: 2014
Referència: Mol Cancer. 2014 Sep 27;13:223. doi: 10.1186/1476-4598-13-223.
Factor d'impacte: 5.397
Tipus de publicació: Article en revista internacional
Autors: Cueva, Juan, Vieito, Maria, Ortega, Eugenia, Mariscal, Javier, Colas, Eva, Castellvi, Josep, Cusido, Maite, Dolcet, Xavier, Nijman, Hans W, Bosse, Tjalling et al.
DOI: 10.1186/1476-4598-13-223

Molecular markers for prostate cancer in formalin-fixed paraffin-embedded tissues.

PMID: 24371818
Revista: BioMed research international [electronic resource]
Any: 2013
Referència: Biomed Res Int. 2013;2013:283635. doi: 10.1155/2013/283635. Epub 2013 Nov 25.
Factor d'impacte:
Tipus de publicació: Carta o abstract
Autors: Doll, Andreas, Reventos, Jaume, Morote, Juan, de Torres, Ines, Sequeiros, Tamara, Garcia, Marta, Montes, Melania, Olivan, Mireia, Rigau, Marina, Colas, Eva et al.
DOI: 10.1155/2013/283635

The present and future of prostate cancer urine biomarkers.

PMID: 23774836
Revista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Any: 2013
Referència: Int J Mol Sci. 2013 Jun 17;14(6):12620-49. doi: 10.3390/ijms140612620.
Factor d'impacte: 2.464
Tipus de publicació: Article en revista internacional
Autors: Rigau, Marina, Olivan, Mireia, Garcia, Marta, Sequeiros, Tamara, Montes, Melania, Colas, Eva, Llaurado, Marta, Planas, Jacques, Torres, Ines de, Morote, Juan et al.
DOI: 10.3390/ijms140612620

[Molecular biology of bone metastases].

PMID: 23793764
Revista: Archivos españoles de urología
Any: 2013
Referència: Arch Esp Urol. 2013 Jun;66(5):463-74.
Factor d'impacte:
Tipus de publicació: Carta o abstract
Autors: Reventos, Jaume, Doll, Andreas, Garcia, Marta, Rigau, Marina, Olivan, Mireia, Montes, Melania, Sequeiros, Tamara, Llaurado, Marta, Colas, Eva, Morote, Juan et al.
DOI:

Molecular diagnosis of endometrial cancer from uterine aspirates.

PMID: 23649867
Revista: INTERNATIONAL JOURNAL OF CANCER
Any: 2013
Referència: Int J Cancer. 2013 Nov 15;133(10):2383-91. doi: 10.1002/ijc.28243. Epub 2013 Jun 21.
Factor d'impacte: 6.198
Tipus de publicació: Article en revista internacional
Autors: Xercavins, Jordi, Perez-Sanchez, Cristina, Colas, Eva, Cabrera, Silvia, Falcon, Orlando, Sanchez-Del-Rio, Angel, Garcia, Enrique, Fernandez-de-Castillo, Luis, Muruzabal, Juan Carlos, Alvarez, Elena et al.
DOI: 10.1002/ijc.28243

Notch-mediated induction of N-cadherin and alpha9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells.

PMID: 22976797
Revista: BRITISH JOURNAL OF CANCER
Any: 2012
Referència: Br J Cancer. 2012 Oct 9;107(8):1374-83. doi: 10.1038/bjc.2012.411. Epub 2012 Sep 13.
Factor d'impacte: 5.042
Tipus de publicació: Article en revista internacional
Autors: Sanchez de Toledo, J, Roma, J, Gallego, S, Toran, N, Reventos, J, Almazan-Moga, A, Masia, A, Velasco, P et al.
DOI: 10.1038/bjc.2012.411

The EMT signaling pathways in endometrial carcinoma.

PMID: 22911547
Revista: Clinical & Translational Oncology
Any: 2012
Referència: Clin Transl Oncol. 2012 Oct;14(10):715-20. doi: 10.1007/s12094-012-0866-3. Epub 2012 Aug 22.
Factor d'impacte: 1.327
Tipus de publicació: Revisió en revista internacional
Autors: Garcia, Angel, Ramon Y Cajal, Santiago, Moreno-Bueno, Gema, Dolcet, Xavier, Alameda, Francesc, Palacios, Jose, Prat, Jaime, Doll, Andreas, Matias-Guiu, Xavier, Abal, Miguel et al.
DOI: 10.1007/s12094-012-0866-3

Molecular bases of endometrial cancer: New roles for new actors in the diagnosis and the therapy of the disease.

PMID: 22037169
Revista: MOLECULAR AND CELLULAR ENDOCRINOLOGY
Any: 2012
Referència: Mol Cell Endocrinol. 2012 Jul 25;358(2):244-55. Epub 2011 Oct 20.
Factor d'impacte: 4.192
Tipus de publicació: Revisió en revista internacional
Autors: , , , , , , , , , et al.
DOI: 10.1016/j.mce.2011.10.003

Analysis of gene expression regulated by the ETV5 transcription factor in OV90 ovarian cancer cells identifies FoxM1 over-expression in ovarian cancer.

PMID: 22589409
Revista: MOLECULAR CANCER RESEARCH
Any: 2012
Referència: Mol Cancer Res. 2012 Jul;10(7):914-24. doi: 10.1158/1541-7786.MCR-11-0449. Epub 2012 May 15.
Factor d'impacte: 4.288
Tipus de publicació: Article en revista internacional
Autors: , , , , , , et al.
DOI: 10.1158/1541-7786.MCR-11-0449

Apoptosis-like cell death induction and aberrant fibroblast properties in human incisional hernia fascia.

PMID: 21641387
Revista: AMERICAN JOURNAL OF PATHOLOGY
Any: 2011
Referència: Am J Pathol. 2011 Jun;178(6):2641-53.
Factor d'impacte: 5.224
Tipus de publicació: Article en revista internacional
Autors: Guillem-Marti, Jordi, Lopez-Cano, Manuel, Huguet, Pere, Ramon-Y-Cajal, Santiago, Reventos, Jaume, Armengol, Manel, Arbos, Maria A, Quiles, Maria T, Diaz, Ramon et al.
DOI: 10.1016/j.ajpath.2011.02.044

High risk endometrial carcinoma profiling identifies TGF-{beta}1 as a key factor in the initiation of tumor invasion.

PMID: 21613448
Revista: MOLECULAR CANCER THERAPEUTICS
Any: 2011
Referència: Mol Cancer Ther. 2011 Aug;10(8):1357-66. Epub 2011 May 25.
Factor d'impacte: 5.225
Tipus de publicació: Article en revista internacional
Autors: , , , , , , , , , et al.
DOI: 10.1158/1535-7163.MCT-10-1019

A Three-Gene panel on urine increases PSA specificity in the detection of prostate cancer.

PMID: 21520154
Revista: PROSTATE
Any: 2011
Referència: Prostate. 2011 Dec;71(16):1736-45. doi: 10.1002/pros.21390. Epub 2011 Apr 25.
Factor d'impacte: 3.377
Tipus de publicació: Article en revista internacional
Autors: , , , , , , , , , et al.
DOI: 10.1002/pros.21390

Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.

PMID: 20970160
Revista: HUMAN PATHOLOGY
Any: 2011
Referència: Hum Pathol. 2011 Jan;42(1):57-67. Epub 2010 Oct 20.
Factor d'impacte: 2.998
Tipus de publicació: Article en revista internacional
Autors: , , , , , , et al.
DOI: 10.1016/j.humpath.2010.01.025

Human SHBG mRNA Translation Is Modulated by Alternative 5'-Non-Coding Exons 1A and 1B.

PMID: 21079794
Revista: PLoS One
Any: 2010
Referència: PLoS One. 2010 Nov 4;5(11):e13844.
Factor d'impacte: 4.351
Tipus de publicació: Article en revista internacional
Autors: , , , , , , et al.
DOI: 10.1371/journal.pone.0013844

Behavior of the PCA3 gene in the urine of men with high grade prostatic intraepithelial neoplasia.

PMID: 20607245
Revista: WORLD JOURNAL OF UROLOGY
Any: 2010
Referència: World J Urol. 2010 Dec;28(6):677-80. Epub 2010 Jul 7.
Factor d'impacte: 2.629
Tipus de publicació: Article en revista internacional
Autors: , , , , , , , , , et al.
DOI: 10.1007/s00345-010-0580-0

PSGR and PCA3 as biomarkers for the detection of prostate cancer in urine.

PMID: 20672322
Revista: PROSTATE
Any: 2010
Referència: Prostate. 2010 Dec 1;70(16):1760-7.
Factor d'impacte: 3.081
Tipus de publicació: Article en revista internacional
Autors: , , , , , , , , , et al.
DOI: 10.1002/pros.21211

A transcriptional signature associated with the onset of benign prostate hyperplasia in a canine model.

PMID: 20687213
Revista: PROSTATE
Any: 2010
Referència: Prostate. 2010 Sep 15;70(13):1402-12.
Factor d'impacte: 3.081
Tipus de publicació: Article en revista internacional
Autors: Gallardo-Arrieta, F, Doll, A, Rigau, M, Mogas, T, Juanpere, N, Garcia, F, Morote, J, Nunez, F, Abal, M, Lloreta, J et al.
DOI: 10.1002/pros.21175

MMPs/TIMPs and inflammatory signalling deregulation in human incisional hernia tissues.

PMID: 19397782
Revista: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Any: 2009
Referència: J Cell Mol Med. 2009 Nov-Dec;13(11-12):4432-43.
Factor d'impacte: 5.114
Tipus de publicació: Article en revista internacional
Autors: , , , , , , , , , et al.
DOI: 10.1111/j.1582-4934.2008.00637.x

Identification, characterization and expression of novel Sex Hormone Binding Globulin alternative first exons in the human prostate.

PMID: 19534810
Revista: BMC MOLECULAR BIOLOGY
Any: 2009
Referència: BMC Mol Biol. 2009 Jun 17;10:59.
Factor d'impacte: 2.81
Tipus de publicació: Article en revista internacional
Autors: Munell, Francina, Morote, Joan, Pinos, Tomas, Barbosa-Desongles, Anna, Hurtado, Antoni, Santamaria-Martinez, Albert, de Torres, Ines, Reventos, Jaume et al.
DOI: 10.1186/1471-2199-10-59

An orthotopic endometrial cancer mouse model demonstrates a role for RUNX1 in distant metastasis.

PMID: 19384951
Revista: INTERNATIONAL JOURNAL OF CANCER
Any: 2009
Referència: Int J Cancer. 2009 Jul 15;125(2):257-63.
Factor d'impacte: 4.734
Tipus de publicació: Article en revista internacional
Autors: Abal, Miguel, Doll, Andreas, Gonzalez, Marta, Colas, Eva, Monge, Marta, Xercavins, Jordi, Capella, Gabriel, Diaz, Berta, Gil-Moreno, Antonio, Alameda, Francesc et al.
DOI: 10.1002/ijc.24330

Individual variations of serum testosterone in patients with prostate cancer receiving androgen deprivation therapy.

PMID: 19007366
Revista: BJU INTERNATIONAL
Any: 2009
Referència: BJU Int. 2009 Feb;103(3):332-5; discussion 335.
Factor d'impacte: 2.704
Tipus de publicació: Article en revista internacional
Autors: Morote, Juan, Planas, Jacques, Salvador, Carlos, Raventos, Carles X, Catalan, Roberto, Reventos, Jaume et al.
DOI: 10.1111/j.1464-410X.2008.08062.x

Estrogen receptor beta displays cell cycle-dependent expression and regulates the G1 phase through a non-genomic mechanism in prostate carcinoma cells.

PMID: 18607069
Revista: CELLULAR ONCOLOGY
Any: 2008
Referència: Cell Oncol. 2008;30(4):349-65.
Factor d'impacte: 4.17
Tipus de publicació: Article en revista internacional
Autors: de Torres, Ines, Bellmunt, Joaquim, Reventos, Jaume, Munell, Francina, Morote, Joan, Santamaria-Martinez, Albert, Barquinero, Jordi, Hurtado, Antoni, Pinos, Tomas, Barbosa-Desongles, Anna et al.
DOI:

Tesis

Valor pronóstico de la linfadenectomía aórtica extraperitoneal en cáncer de cérvix localmente avanzado

Doctorand: Rocio Luna Guibourg
Director/s: Berta Diaz Feijoo, Antonio Gil Moreno
Universitat: Universitat Autònoma de Barcelona
Any: 2022

Ganglis limfàtics sentinella en el carcinoma d'endometri: "Passat, present i futur"

Doctorand: Natalia Rodriguez Gómez - Hidalgo
Director/s: Silvia Cabrera Diaz, Maria Asuncion Perez Benavente, Antonio Gil Moreno
Universitat: Universitat Autònoma de Barcelona
Any: 2022

Biomarcadors en endometriosi

Doctorand: Taisiia Melnychuk
Director/s: Antonio Gil Moreno, Eva Colas Ortega
Universitat:
Any: 2022

Aproximació a la medicina personalitzada en càncer d'endometri pel control de la malaltia recurrent

Doctorand: Carlos Lopez Gil
Director/s: Antonio Gil Moreno, Eva Colas Ortega
Universitat:
Any: 2022

Estadificació prequirúrgica del carcinoma endometrial mitjançant ecografia en dos-tres

Doctorand: Montserrat Cubo Abert
Director/s: Antonio Gil Moreno
Universitat:
Any: 2021

Resultats a llarg termini del tractament quirúrgic amb diferents vies d'abordatge per a la histerectomia radical en el càncer de cèrvix inicial

Doctorand: Sabina Salicrú Riera
Director/s: Antonio Gil Moreno
Universitat:
Any: 2021

Utilidad diagnóstica del test intraoperatorio del virus del papiloma humano como marcador precoz de curación o recidiva en mujeres con neoplasia intraepitelial cervical de alto grado (HSIL/CIN2-3)

Doctorand: Jordi Rabasa Antonijuan
Director/s: Antonio Gil Moreno
Universitat: Universidad Autònoma de Barcelona
Any: 2020

Impacto del uso de la sutura de absorción retardada en la incidencia de dehiscencia de la cúpula vaginal, después de la histerectomía laparoscópica y robótica

Doctorand: Elena Suarez Salvador
Director/s: Antonio Gil Moreno
Universitat: Universidad Autònoma de Barcelona
Any: 2020

Estudi de cohorts prospectiu del tractament quirúrgic de la incontinència urinària de esforç femenina amb bandes suburetrals transobturadores

Doctorand: Jose Luis Poza Barrasus
Director/s: Antonio Gil Moreno
Universitat: Universidad Autònoma de Barcelona
Any: 2020

Targeting mitosis in ovarian cancer: The study of Bora as a future therapeutic avenue

Doctorand: Alfonso Parrilla Ocon
Director/s: Anna Santamaria Margalef
Universitat: Universidad Autònoma de Barcelona
Any: 2019

EV-associated miRNAs as a new source of biomarkers in endometrial, colorectal and lung cancers

Doctorand: Berta Román Canal
Director/s: Eva Colas Ortega
Universitat: Universidad Autònoma de Barcelona
Any: 2019

Metabolomic study for the identification of diagnostic markers and the characterization of the dissemination process of endometrial cancer

Doctorand: Tatiana Altadill Vallespi
Director/s: Antonio Gil Moreno, Eva Colas Ortega
Universitat: Universidad Autònoma de Barcelona
Any: 2018

Molecular alteracions in eutopic endometrium of women with endometriosis and implications in its diagnostic

Doctorand: Júlia Vallvé Juanico
Director/s: Xavier Santamaria Costa, Antonio Gil Moreno
Universitat: Universidad Autònoma de Barcelona
Any: 2018

The role of activated leukocyte cell adhesion molecule (ALCAM) in endometrial cancer progression and dissemination

Doctorand: Laura Devis Jauregui
Director/s: Jaume Reventós Puigjaner, Antonio Gil Moreno, Eva Colas Ortega
Universitat: Universidad Autònoma de Barcelona
Any: 2017

Nuevas moléculas asociadas al cáncer de ovario para la mejora de su diagnóstico y tratamiento

Doctorand: Lucia Lanau Angulo
Director/s: Jaume Reventós Puigjaner, Marina Rigau Resina, Anna Santamaria Margalef
Universitat: Universidad Autònoma de Barcelona
Any: 2017

Protein signatures in uterine aspirates to improve diagnosis of endometrial cancer. The CEMARK project

Doctorand: Elena Martínez García
Director/s: Antonio Gil Moreno, Jaume Reventós Puigjaner, Eva Colas Ortega
Universitat: Universidad Autònoma de Barcelona
Any: 2017

Micro-RNAs in ovarian cancer as tools for diagnosis and therapy

Doctorand: Blanca Majem Cavaller
Director/s: Anna Santamaria Margalef
Universitat: Universidad Autònoma de Barcelona
Any: 2017

Estudio comparativo entre cirugía primaria y cirurgia de intervalo en el estadio IIIC del cáncer de ovario

Doctorand: José Luis Sánchez Iglesias
Director/s: Antonio Gil Moreno
Universitat: Universidad Autònoma de Barcelona
Any: 2014

Identification of New Urine Biomarkers for the Detection of Prostate Cancer

Doctorand: Marina Rigau Resina
Director/s: Jaume Reventós Puigjaner, Andreas He Doll , Joan Morote Robles
Universitat: Universidad Autònoma de Barcelona
Any: 2011

Endometrial carcinoma: improving diagnosis, deconstructing carcinoma invasion and pursuing new therapeutic strategies

Doctorand: Eva Colas Ortega, Eva Colas Ortega
Director/s: Jaume Reventós Puigjaner, Miguel Abal Posada
Universitat: Universidad Autònoma de Barcelona
Any: 2011

Estudio prospectivo para la validacion de la tecnica del ganclio centinela en cáncer de cervix uterino inicial

Doctorand: Berta Diaz Feijoo
Director/s:
Universitat: Universidad Autònoma de Barcelona
Any: 2007

Actualitat

Notícies

Els projectes s’han avaluat en funció de la seva qualitat i metodologia, rellevància científica, sanitària i social, i valor innovador i transformador, entre altres aspectes.

Durant el debat s’han intercanviat experiències entre donants i investigadors on es demostra l’impacte de la col·laboració de la ciutadania per fer avançar la ciència.

En el Dia Mundial de la Recerca en Càncer, destaquem la recerca per millorar els tractaments contra el càncer infantil i de l’adult gràcies a tècniques innovadores.