Vés al contingut

Recerca Biomèdica en Melanoma

El grup de Recerca Biomèdica en Melanoma està interessat en l'estudi dels càncers de pell, en particular, del melanoma. Els nostres interessos se centren en l'estudi de les causes moleculars d'aquestes malalties, per tal de desenvolupar teràpies eficaces contra elles. La nostra investigació es realitza de manera pròxima als pacients, ja que el nostre objectiu principal és traslladar els nostres descobriments a la clínica tan ràpid com sigui possible. Per això, el nostre grup multidisciplinari està associat a dermatòlegs, oncòlegs i patòlegs, a més d’estar-ho als investigadors bàsics del grup que pretenen respondre a qüestions clíniques rellevants que necessiten una resposta biològica. 

El nostre flux de treball contempla l'obtenció d'informació dels pacients (dades genètiques, clíniques, funcionals, etc.), que és traslladada a models animals (models genèticament modificats, PDX, etc.) i experiments in vitro per a respondre a les preguntes plantejades. Aquests resultats s’usen amb les següents finalitats:

  • Dissenyar noves aproximacions terapèutiques.
  • Desenvolupar nous fàrmacs.
  • Posar en marxa estudis preclínics que es traslladaran als pacients.

Equip

Juan Angel Recio Conde

Juan Angel Recio Conde

Cap de grup
Recerca Biomèdica en Melanoma
Llegir més
Carla Ferrándiz Pulido

Carla Ferrándiz Pulido

Investigador/a sènior
Recerca Biomèdica en Melanoma
Llegir més
Roberto Orsenigo

Roberto Orsenigo

Investigador/a predoctoral
Recerca Biomèdica en Melanoma
Llegir més
Yuxin Ding

Yuxin Ding

Investigador/a predoctoral
Recerca Biomèdica en Melanoma
Llegir més
Berta Ferrer Fábrega

Berta Ferrer Fábrega

Recerca Biomèdica en Melanoma
Llegir més
Carlos González Cruz

Carlos González Cruz

Investigador/a predoctoral
Recerca Biomèdica en Melanoma
Llegir més
Juan Angel Recio Conde

Juan Angel Recio Conde

Cap de grup
Recerca Biomèdica en Melanoma
Llegir més
Carla Ferrándiz Pulido

Carla Ferrándiz Pulido

Investigador/a sènior
Recerca Biomèdica en Melanoma
Llegir més
Roberto Orsenigo

Roberto Orsenigo

Investigador/a predoctoral
Recerca Biomèdica en Melanoma
Llegir més
Yuxin Ding

Yuxin Ding

Investigador/a predoctoral
Recerca Biomèdica en Melanoma
Llegir més
Berta Ferrer Fábrega

Berta Ferrer Fábrega

Recerca Biomèdica en Melanoma
Llegir més
Carlos González Cruz

Carlos González Cruz

Investigador/a predoctoral
Recerca Biomèdica en Melanoma
Llegir més

Línies de recerca

Deciphering oncogene-driven metabolism settings in malignant melanoma with therapeutic purposes

Metabolic settings of aggressive tumor cells adapt to their energetic and anabolic demands. While limited success in cancer treatment using targeted therapy has been accomplished, the altered metabolism of tumor cells compared to normal cells, provides a viable novel target for a non-toxic chemotherapeutic approach. Since tumor cells can utilize different metabolic strategies that have only now being elucidated, deciphering which metabolic settings are associated to a particular mutational status would be helpful to both design novel therapeutic strategies and stratify patients for treatment. In melanoma ~50% of tumors present activating mutations in BRAF (BRAFV600E) and another 20% present activating mutations in NRAS (NRASQ61L). While targeted therapy of BRAFV600E mutant tumors has been partially successful there is no therapeutic alternative for patients harboring NRASQ61L mutant tumors. Despite the fact that these molecules affect the same pathway (RAS-ERK1/2), BRAFV600E and NRASQ61L mutant cells behave and respond differently to therapy and to metabolic stress. Understanding the metabolic settings of BRAFV600E and NRASQ61L mutant melanoma tumors would help to sensitize them, overcome resistance mechanisms to therapy and target them according to their genetic alterations. This project is been supported by Marie Curie actions.


Expected results: After execution of this project the main expected results are:

1. To define the different metabolic settings of melanomas harboring diferent oncogenic mutations

2. To identify the biochemical mechanism responsible for the differential metabolic stress response acconding to their genotype

3. To design of novel therapeutic alternatives to treat melanoma tumors.

IP: -

Novel therapeutic strategies for melanoma treatment

IP: -

Preclinical study in lung and melanoma using ALDH specific inhibitors

To translate our reseach into the clinic is one of our main objetives. We are currently conducting a preclinical study in colaboration with the Industry to test the therapeutic capabilities of ALDH isoform-specific inhibidors in melanoma, lung and breast tumors. The aims of this project are:

To identify the ALDH isoforms and the metabolic settings associated to oncògenes


To verify a cause and effect relationship between the increased activity of a specific ALDH isoform and the resistance to cell death manifest.


To identify which of the endogenous substrates of ALDH and corresponding reaction products are specifically involved in cell death resistance.


To evaluate the therapeutic efficacy of specific inhibitors of ALDHs

IP: -

Role of LKB1 in tumor biology: LKB1 role in UVB-induced DNA damage response

Environmental insults are directly involved in cancer development. In particular, Ultraviolet (UV) radiation has been associated to the acquisition of different types of skin cancer and premature skin aging. UV radiation causes modifications in the genetic material of cells (DNA) that if not repaired properly will lead to a mutated DNA (mutated genes) which might trigger the development of cancer. Understanding the molecular basis of the UV-induced DNA damage response is important to elucidate the mechanisms of skin tumorigenesis.


In the study, published in Plos Genetics, the authors used a UV-induced skin cancer mouse model (Hepatocyte growth factor (HGF) transgenic mice), where one of the two Lkb1 gene alleles was deleted (haploinsufficiency), and consequently the amounts of LKB1 protein was half of the normal levels. A single dose of UVB radiation in Lkb1 haploinsufficient neonates  mice expressing HGF was enough to induced the quickly development of squamous cell carcinomas, and this, was associated to a deficient response in DNA damage repair.  Moreover, cells harboring the damaged DNA were resistant to cell death (apoptosis).  Thus, lack of LKB1 promotes a double effect: cells not only fail to repair the damage in their DNA, but they do not die, leading to the accumulation of mutated cells and the development of tumors. The research team has obtained similar results (to be published soon) in two additional mouse models of melanoma, a much more lethal type of UV-induced skin cancer.


One of the beauties of this model is that reflects the real scenario for cancer adquisition where initially just one of gene copies is damaged. It also reproduces a tumor related to chronic DNA damage using a single dose of UV radiation, underlining the importance of this protein’s function. 


LKB1 mutations have been found epithelial human cancers associated to environmental insults. “However, this is the first study that links LKB1 to the UV-induced DNA repair responses” explains Dr. Recio, “and provides an important insight into how cells can defend themselves from external genotoxic damage”.


Importantly, these results can be extrapolated to human cancer. In fact, when examining the expression of LKB1 protein in samples from patients with skin tumors, the authors found that roughly half of these samples showed low or no expression of LKB1.  Furthermore, absence of the protein was detected in all stages of the disease, particularly in UV-exposed skin areas, suggesting that the loss of expression of LKB1 is an early event and very likely contributes to UV-induced skin cancer development.


In the near future, we will be evaluating LKB1 as a prognostic risk factor for UV–induced skin cancer. They also are investigating the different factors that may alter LKB1 expression, with a particular emphasis in families with skin cancer predisposition or skin cancer history.

IP: -

Projectes

Tumor dependent immune evasive mechanisms in melanoma

IP: Juan Angel Recio Conde
Col·laboradors: Paula Granado Martinez, Kimberley Anne McGrail Fernández, Vicente García-Patos Briones, Berta Ferrer Fábrega, Yuxin Ding, Roberto Orsenigo
Entitat finançadora: Instituto de Salud Carlos III
Finançament: 321250
Referència: PI23/00428
Durada: 01/01/2024 - 31/12/2026

Development of TET2 activating drugs for the treatment of melanoma

IP: Juan Angel Recio Conde
Col·laboradors: -
Entitat finançadora: Ministerio de Ciencia e Innovación-MICINN
Finançament: 233708
Referència: CPP2022-009781
Durada: 01/11/2023 - 31/10/2026

Ministerio de Ciencia

Beca VHIR PhD

IP: Juan Angel Recio Conde
Col·laboradors: Sira Rodrigo Bosch, Laia Perez Lasarte, Yuxin Ding
Entitat finançadora: Fundació Institut de Recerca HUVH
Finançament: 69188.74
Referència: VPHD/YUXUNG_D
Durada: 01/09/2023 - 31/08/2026

Discovering intratumoral immune-cell resistance mechanisms to immunotherapy response

IP: Juan Angel Recio Conde
Col·laboradors: Roberto Orsenigo
Entitat finançadora: Fundació "La Caixa"
Finançament: 115092
Referència: CAIXA/INPHINIT/2022/ORSENIGO
Durada: 01/11/2022 - 31/10/2025

Publicacions

Mucosal Melanoma Clinical Management and Prognostic Implications: A Retrospective Cohort Study.

PMID: 38201654
Revista: Cancers
Any: 2024
Referència: Cancers (Basel). 2024 Jan 3;16(1):227. doi: 10.3390/cancers16010227.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Bassas-Freixas, Patricia; Bodet, Domingo; Clavero-Rovira, Laia; Ferrandiz-Pulido, Carla; Ferrer, Berta; Garcia-Patos, Vicente; Gomez-Tomas, Alvaro; Hernandez-Losa, Javier; Munoz-Couselo, Eva; Perez-Benavente, Assumpcio et al.
DOI: 10.3390/cancers16010227

Oral linezolid compared with benzathine penicillin G for treatment of early syphilis in adults (Trep-AB Study) in Spain: a prospective, open-label, non-inferiority, randomised controlled trial.

PMID: 38211601
Revista: LANCET INFECTIOUS DISEASES
Any: 2024
Referència: Lancet Infect Dis. 2024 Jan 8:S1473-3099(23)00683-7. doi: 10.1016/S1473-3099(23)00683-7.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Alemany, Andrea; Alvarez, Marlene; Arando, Maider; Canut, Andres; Descalzo Jorro, Vicent; Farre, Magi; G-Beiras, Camila; Galvan-Casas, Cristina; Garcia-Patos, Vicente; Giacani, Lorenzo et al.
DOI: 10.1016/S1473-3099(23)00683-7

Prognostic factors for satellitosis or in-transit metastasis in cutaneous squamous cell carcinoma: A multicentric cohort study.

PMID: 36907554
Revista: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Any: 2023
Referència: J Am Acad Dermatol. 2023 Jul;89(1):119-127. doi: 10.1016/j.jaad.2023.02.048. Epub 2023 Mar 10.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Abril-Perez, Carlos; Aguayo-Ortiz, Rafael S; Altemir-Vidal, Arcadi; Bea-Ardebol, Sonia; Becerril, Sara; Bodet-Castillo, Domingo; Botella-Estrada, Rafael; Canueto, Javier; Deza, Gustavo; Ferrandiz-Pulido, Carla et al.
DOI: 10.1016/j.jaad.2023.02.048

Therapeutic Outcomes and Survival Analysis of Extramammary Paget's Disease: A multicentre retrospective study of 249 patients.

PMID: 37704106
Revista: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Any: 2023
Referència: J Am Acad Dermatol. 2023 Sep 11:S0190-9622(23)02690-7. doi: 10.1016/j.jaad.2023.08.088.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Aguayo-Ortiz, Rafael S; Alcaraz, Inmaculada; Arandes-Marcocci, Jorge; Barchino-Ortiz, Lucia; Bea-Ardebol, Sonia; Delgado, Yolanda; Deza, Gustavo; Dradi, Giulia Greta; Escola, Helena; Escola-Rodriguez, Alba et al.
DOI: 10.1016/j.jaad.2023.08.088

Nephro-oncology: clinical and biochemical aspects of kidney disease and cancer.

PMID: 37159995
Revista: ACTA BIOCHIMICA POLONICA
Any: 2023
Referència: Acta Biochim Pol. 2023 May 9. doi: 10.18388/abp.2020_6588.
Factor d'impacte:
Tipus de publicació: Article en revista internacional
Autors: Adamczak, Marcin; Chudek, Jerzy; Debska-Slizien, Alicja; Durlik, Magdalena; Ferrandiz-Pulido, Carla; Foroncewicz, Bartosz; Gellert, Ryszard; Krajewska, Magdalena; Kurnatowska, Ilona; Lizakowski, Slawomir et al.
DOI: 10.18388/abp.2020_6588

[Not Available].

PMID: 37088285
Revista: Actas dermo-sifiliograficas
Any: 2023
Referència: Actas Dermosifiliogr. 2023 Apr 21:S0001-7310(23)00318-6. doi: 10.1016/j.ad.2023.04.022.
Factor d'impacte:
Tipus de publicació: Article en revista nacional
Autors: Bea-Ardebol, S; Bonfill-Orti, M; Deza-Vargas, L G; Feal, C; Fernandez-de-Misa, R; Ferrandiz-Pulido, C; Florez, A; Galiano-Mejias, S; Hernandez-Hernandez, N; Jaka, A et al.
DOI: 10.1016/j.ad.2023.04.022

Prurigiform angiomatosis: report of three cases and review of the literature.

PMID: 35781803
Revista: INTERNATIONAL JOURNAL OF DERMATOLOGY
Any: 2022
Referència: Int J Dermatol. 2022 Jul 3. doi: 10.1111/ijd.16345.
Factor d'impacte: 2.736
Tipus de publicació: Carta o abstract
Autors: Fernandez-Figueras, Maria-Teresa; Garcia-Patos Briones, Vicente; Perez-Munoz, Noelia; Barrabes-Torrella, Cristina; Salleras-Redonnet, Montse; Quintana-Codina, Monica; Gonzalez-Cruz, Carlos et al.
DOI: 10.1111/ijd.16345

Effects of COVID-19 Lockdown on Tumour Burden of Melanoma and Cutaneous Squamous Cell Carcinoma.

PMID: 34396424
Revista: ACTA DERMATO-VENEREOLOGICA
Any: 2021
Referència: Acta Derm Venereol. 2021 Aug 25;101(8):adv00525. doi: 10.2340/00015555-3890.
Factor d'impacte: 4.437
Tipus de publicació: Article en revista internacional
Autors: Tejera-Vaquerizo, Antonio, Paradela, Sabela, Toll, Agusti, Santos-Juanes, Jorge, Jaka, Ane, Taberner, Rosa, Rodenas-Herranz, Teresa, Garcia-Donoso, Carmen, Puig, Susana, Nagore, Eduardo et al.
DOI: 10.2340/00015555-3890

Posttransplant Kaposi sarcoma: Analysis of a series of 13 patients.

PMID: 34246484
Revista: MEDICINA CLINICA
Any: 2021
Referència: Med Clin (Barc). 2021 Oct 8;157(7):339-343. doi: 10.1016/j.medcli.2021.04.030. Epub 2021 Jul 7.
Factor d'impacte: 1.725
Tipus de publicació: Carta o abstract
Autors: Ferrer Fabregas, Berta, Gonzalez-Cruz, Carlos, Ferrandiz-Pulido, Carla, Garcia-Patos Briones, Vicente et al.
DOI: 10.1016/j.medcli.2021.04.030

Melanoma in Solid Organ Transplant Recipients.

PMID: 33197437
Revista: Actas dermo-sifiliograficas
Any: 2021
Referència: Actas Dermosifiliogr. 2021 Mar;112(3):216-224. doi: 10.1016/j.ad.2020.11.005. Epub 2020 Nov 13.
Factor d'impacte: 0
Tipus de publicació: Revisió en revista nacional
Autors: Gonzalez-Cruz, C, Ferrandiz-Pulido, C, Garcia-Patos Briones, V et al.
DOI: 10.1016/j.ad.2020.11.005

Mediastinal FDG-positive lymph nodes simulating melanoma progression: drug-induced sarcoidosis like/lymphadenopathy related to ipilimumab.

PMID: 33509865
Revista: BMJ case reports
Any: 2021
Referència: BMJ Case Rep. 2021 Jan 28;14(1). pii: 14/1/e237310. doi: 10.1136/bcr-2020-237310.
Factor d'impacte: 0
Tipus de publicació: Carta o abstract
Autors: Gonzalez-Cruz, Carlos, Bodet, Domingo, Munoz-Couselo, Eva, Garcia-Patos, Vicente et al.
DOI: 10.1136/bcr-2020-237310

Leucocytoclastic vasculitis in a patient with COVID-19 with positive SARS-CoV-2 PCR in skin biopsy.

PMID: 33122236
Revista: BMJ case reports
Any: 2020
Referència: BMJ Case Rep. 2020 Oct 29;13(10). pii: 13/10/e238039. doi: 10.1136/bcr-2020-238039.
Factor d'impacte: 0
Tipus de publicació: Article en revista internacional
Autors: Camprodon Gomez, Maria, Gonzalez-Cruz, Carlos, Ferrer, Berta, Barbera, Maria Jesus et al.
DOI: 10.1136/bcr-2020-238039

Maculopapular eruptions associated to COVID-19: a subanalysis of the COVID-Piel study.

PMID: 32779280
Revista: Dermatologic Therapy
Any: 2020
Referència: Dermatol Ther. 2020 Nov;33(6):e14170. doi: 10.1111/dth.14170. Epub 2020 Sep 9.
Factor d'impacte: 2.327
Tipus de publicació: Article en revista internacional
Autors: Llamas-Velasco, Mar, Carnero-Gonzalez, Lucia, Garcia-Gavin, Juan, Baniandres, Ofelia, Gonzalez-Cruz, Carlos, Morillas-Lahuerta, Victor, Cubiro, Xavier, Figueras, Ignasi, Selda-Enriquez, Gerald, Fusta-Novell, Xavier et al.
DOI: 10.1111/dth.14170

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.

PMID: 32647375
Revista: Communications Biology
Any: 2020
Referència: Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0.
Factor d'impacte: 4.165
Tipus de publicació: Article en revista internacional
Autors: Granado-Martinez, Paula, Garcia-Ortega, Sara, Gonzalez-Sanchez, Elena, McGrail, Kimberley, Selgas, Rafael, Grueso, Judit, Gil, Rosa, Naldaiz-Gastesi, Neia, Rhodes, Ana C, Hernandez-Losa, Javier et al.
DOI: 10.1038/s42003-020-1092-0

Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases.

PMID: 32348545
Revista: BRITISH JOURNAL OF DERMATOLOGY
Any: 2020
Referència: Br J Dermatol. 2020 Jul;183(1):71-77. doi: 10.1111/bjd.19163. Epub 2020 Jun 10.
Factor d'impacte: 7
Tipus de publicació: Article en revista internacional
Autors: Galvan Casas, C, Catala, A, Carretero Hernandez, G, Rodriguez-Jimenez, P, Fernandez Nieto, D, Rodriguez-Villa Lario, A, Navarro Fernandez, I, Ruiz-Villaverde, R, Falkenhain, D, Llamas Velasco, M et al.
DOI: 10.1111/bjd.19163

Proportion of Potentially Avoidable Referrals From Primary Care to Dermatologists for Cystic Lesions or Benign Neoplasms in Spain: Analysis of Data from the DIADERM Study.

PMID: 31153547
Revista: Actas dermo-sifiliograficas
Any: 2019
Referència: Actas Dermosifiliogr. 2019 Oct;110(8):659-665. doi: 10.1016/j.ad.2019.02.003. Epub 2019 May 29.
Factor d'impacte: 0
Tipus de publicació: Article en revista nacional
Autors: Gonzalez-Cruz, C, Descalzo, M A, Arias-Santiago, S, Molina-Leyva, A, Gilaberte, Y, Fernandez-Crehuet, P, Viera-Ramirez, A, Fernandez-Penas, P, Taberner, R, Buendia-Eisman, A et al.
DOI: 10.1016/j.ad.2019.02.003

Indurated Papules on the Face.

PMID: 30850121
Revista: Actas dermo-sifiliograficas
Any: 2019
Referència: Actas Dermosifiliogr. 2019 Sep;110(7):599-600. doi: 10.1016/j.ad.2018.01.018. Epub 2019 Mar 6.
Factor d'impacte: 0
Tipus de publicació: Article en revista nacional
Autors: Gonzalez-Cruz, C, Cabezas Calderon, V, Garcia-Patos Briones, V et al.
DOI: 10.1016/j.ad.2018.01.018

Cutaneous infections by dematiaceous opportunistic fungi: diagnosis and management in 11 solid organ transplant recipients.

PMID: 30230044
Revista: MYCOSES
Any: 2019
Referència: Mycoses. 2019 Feb;62(2):121-127. doi: 10.1111/myc.12853. Epub 2018 Oct 17.
Factor d'impacte: 3.065
Tipus de publicació: Article en revista internacional
Autors: Ferrandiz-Pulido, C, Martin-Gomez, M T, Repiso, T, Juarez, C, Ferrer, B, Lopez-Lerma, I, Gonzalez-Cruz, C, Moreso, F, Roman, A, Garcia-Patos, V et al.
DOI: 10.1111/myc.12853

Lupus panniculitis: Clinicopathological features of a series of 12 patients.

PMID: 30154008
Revista: MEDICINA CLINICA
Any: 2018
Referència: Med Clin (Barc). 2018 Dec 14;151(11):444-449. doi: 10.1016/j.medcli.2018.06.024. Epub 2018 Aug 25.
Factor d'impacte: 1.168
Tipus de publicació: Article en revista nacional
Autors: Gonzalez-Cruz, Carlos, Aparicio Espanol, Gloria, Ferrer Fabrega, Berta, Cabezas Calderon, Victor, Giner Pichel, Mario, Garcia-Patos Briones, Vicente et al.
DOI: 10.1016/j.medcli.2018.06.024

Genetic Profiles of Squamous Cell Carcinomas Associated with Recessive Dystrophic Epidermolysis Bullosa Unveil NOTCH and TP53 Mutations and an Increased MYC Expression.

PMID: 29291383
Revista: JOURNAL OF INVESTIGATIVE DERMATOLOGY
Any: 2018
Referència: J Invest Dermatol. 2018 Jun;138(6):1423-1427. doi: 10.1016/j.jid.2017.12.026. Epub 2017 Dec 29.
Factor d'impacte: 6.448
Tipus de publicació: Article en revista internacional
Autors: Vivancos, A, Garcia-Patos, V, Recio, J A, Bodet, D, Hernandez-Losa, J, Perez-Alea, M, Sans-DeSanNicolas, L, Caratu, G, Vidal-Cortes, O, Sanchez-Redondo, S et al.
DOI: 10.1016/j.jid.2017.12.026

Tesis

Targeting NRAS mutant melanomas through metabolic stress.

Doctorand: Kimberley Anne McGrail Fernández, Kimberley Anne McGrail Fernández
Director/s: Juan Angel Recio Conde
Universitat: Universidad Autònoma de Barcelona
Any: 2021

Study of the in vivo cooperation between oncogenic BRAF, LKB1 loss and UV irradiation

Doctorand: Elena González Sánchez
Director/s: Juan Angel Recio Conde
Universitat: Universidad Autònoma de Barcelona
Any: 2019

Study of the in vivo cooperation between oncogenic BRAF, LKB1 loss and UV irradiation

Doctorand:
Director/s: Juan Angel Recio Conde
Universitat: Universitat Autònoma de Barcelona
Any: 2019

Study of the in vivo cooperation between oncogenic BRAF, LKB1 loss and UV irradiation

Doctorand: Elena González Sánchez
Director/s: Juan Angel Recio Conde
Universitat: Universidad Autònoma de Barcelona
Any: 2019

Mecanismos epigenéticos con valor pronóstico en el carcinoma escamoso cutáneo

Doctorand: Maria eugenia Hernandez Ruiz
Director/s: Vicente García-Patos Briones
Universitat: Universidad Autònoma de Barcelona
Any: 2019

Caracterización de la expresión de ácido ribonucléico mensajero en distintos subtipos histológicos de carcinoma basocelular

Doctorand: Patricia Bassas Freixas
Director/s: Vicente García-Patos Briones, Aleix Prat Aparicio
Universitat: Universidad Autònoma de Barcelona
Any: 2018

Actualitat

Notícies

En el Dia Mundial de la Recerca en Càncer, destaquem la recerca per millorar els tractaments contra el càncer infantil i de l’adult gràcies a tècniques innovadores.

En el Dia Mundial de la Recerca en Càncer, destaquem el model de recerca oncològica del VHIR que permet que els resultats del laboratori es traslladin al més ràpid possible a la pràctica clínica.

Hem superat una exhaustiva avaluació externa de l’OECI que l’acredita com a centre d’excel·lència en l’assistència multidisciplinària als pacients oncològics, recerca, prevenció, innovació assistencial i formació dels professionals.