About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 32896253 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2021 Reference: Clin Exp Rheumatol. 2021 Mar-Apr;39(2):351-356. Epub 2020 Sep 1. Impact factor: 4.473 Publication type: Paper in international publication Authors: Milisenda, Jose C, Pinal-Fernandez, Iago, Lloyd, Thomas E, Grau, Josep Maria, Miller, Frederick W, Selva-O'Callaghan, Albert, Christopher-Stine, Lisa, Stenzel, Werner, Mammen, Andrew L, Corse, Andrea M et al. DOI:
PMID: 32896242 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2021 Reference: Clin Exp Rheumatol. 2021 Mar-Apr;39(2):337-343. Epub 2020 Sep 3. Impact factor: 4.473 Publication type: Paper in international publication Authors: Lopez-Corbeto, Mireia, Martinez-Mateu, Sergio, Pluma, Andrea, Ferrer, Roser, Lopez-Lasanta, Maria, De Agustin, Juan Jose, Barcelo, Mireia, Julia, Antonio, Marsal, Sara et al. DOI:
PMID: 33831619 Journal: Journal of Allergy and Clinical Immunology-In Practice Year: 2021 Reference: J Allergy Clin Immunol Pract. 2021 Jun;9(6):2284-2292. doi: 10.1016/j.jaip.2021.03.038. Epub 2021 Apr 5. Impact factor: 8.861 Publication type: Paper in international publication Authors: Sabate-Bresco, Marina, Rodriguez-Garijo, Nuria, Azofra, Julian, Baeza, Maria Luisa, Donado, Carmen Diaz, Gaig, Pere, Guilarte, Mar, Herrera-Lasso, Valeria, Labrador-Horrillo, Moises, Sala-Cunill, Anna et al. DOI: 10.1016/j.jaip.2021.03.038
PMID: 33831620 Journal: Journal of Allergy and Clinical Immunology-In Practice Year: 2021 Reference: J Allergy Clin Immunol Pract. 2021 Jul;9(7):2844-2852.e5. doi: 10.1016/j.jaip.2021.03.037. Epub 2021 Apr 5. Impact factor: 8.861 Publication type: Paper in international publication Authors: Wagner, Nicola, Wedi, Bettina, Wenzel, Markus, Bilo, Maria Beatrice, Worm, Margitta, Bauer, Andrea, Kreft, Burkhard, Cardona, Victoria, Kraft, Magdalena, Dolle-Bierke, Sabine et al. DOI: 10.1016/j.jaip.2021.03.037
PMID: 31838162 Journal: AUTOIMMUNITY REVIEWS Year: 2020 Reference: Autoimmun Rev. 2020 Feb;19(2):102455. doi: 10.1016/j.autrev.2019.102455. Epub 2019 Dec 12. Impact factor: 7.767 Publication type: Review in international publication Authors: Trallero-Araguas, Ernesto, Matas-Garcia, Ana, Milisenda, Jose C, Selva-O'Callaghan, Albert, Prieto-Gonzalez, Sergio, Padrosa, Joan, Cabrera, Carlos, Reguart, Noemi, Castrejon, Natalia, Sole, Manel et al. DOI: 10.1016/j.autrev.2019.102455
PMID: 31906988 Journal: Journal of Translational Medicine Year: 2020 Reference: J Transl Med. 2020 Jan 6;18(1):4. doi: 10.1186/s12967-019-02184-z. Impact factor: 4.124 Publication type: Paper in international publication Authors: Castro-Marrero, Jesus, Escorihuela, Rosa Maria, Capdevila, Lluis, Castro, Juan Ramos, Zaragoza, Maria Cleofe, Maurel, Sara, Alegre, Jose et al. DOI: 10.1186/s12967-019-02184-z
PMID: 31043678 Journal: PHARMACOGENOMICS JOURNAL Year: 2019 Reference: Pharmacogenomics J. 2019 Dec;19(6):547-555. doi: 10.1038/s41397-019-0090-4. Epub 2019 May 2. Impact factor: 3.503 Publication type: Paper in international publication Authors: Aterido, Adria, Palau, Nuria, Domenech, Eugeni, Nos Mateu, Pilar, Gutierrez, Ana, Gomollon, Fernando, Mendoza, Juan L, Garcia-Planella, Esther, Barreiro-de Acosta, Manuel, Munoz, Fernando et al. DOI: 10.1038/s41397-019-0090-4
PMID: 31036626 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2019 Reference: Ann Rheum Dis. 2019 Jul;78(7):967-973. doi: 10.1136/annrheumdis-2019-215024. Epub 2019 Apr 29. Impact factor: 14.299 Publication type: Paper in international publication Authors: Jousse-Joulin, Sandrine, D'Agostino, Maria Antonietta, Nicolas, Celine, Naredo, Esperanza, Ohrndorf, Sarah, Backhaus, Marina, Tamborrini, Giorgio, Chary-Valckenaere, Isabelle, Terslev, Lene, Bruyn, G A W et al. DOI: 10.1136/annrheumdis-2019-215024
PMID: 31004236 Journal: Metabolomics Year: 2019 Reference: Metabolomics. 2019 Apr 19;15(4):65. doi: 10.1007/s11306-019-1527-0. Impact factor: 3.167 Publication type: Paper in international publication Authors: Guma, Monica, Quehenberger, Oswald, Jain, Mohit, Coras, Roxana, Kavanaugh, Arthur, Boyd, Tristan, Huynh, Quyen, Pedersen, Brian, Armando, Aaron M, Dahlberg-Wright, Signe et al. DOI: 10.1007/s11306-019-1527-0
PMID: 30952369 Journal: GYNECOLOGIC ONCOLOGY Year: 2019 Reference: Gynecol Oncol. 2019 Jun;153(3):549-554. doi: 10.1016/j.ygyno.2019.03.241. Epub 2019 Apr 3. Impact factor: 4.393 Publication type: Paper in international publication Authors: Tejerizo, A, Lago, V, Fotopoulou, C, Chiantera, V, Minig, L, Gil-Moreno, A, Cascales-Campos, P A, Jurado, M, Di Donna, M C, Marina, T et al. DOI: 10.1016/j.ygyno.2019.03.241
PMID: 27988433 Journal: AUTOIMMUNITY REVIEWS Year: 2017 Reference: Autoimmun Rev. 2017 Feb;16(2):168-172. doi: 10.1016/j.autrev.2016.12.008. Epub 2016 Dec 15. Impact factor: 8.961 Publication type: Review in international publication Authors: Martinez-Valle, Fernando, Fernandez-Codina, Andreu, Pinal-Fernandez, Iago, Orozco-Galvez, Olimpia, Vilardell-Tarres, Miquel et al. DOI: 10.1016/j.autrev.2016.12.008
PMID: 28086002 Journal: Arthritis & Rheumatology Year: 2017 Reference: Arthritis Rheumatol. 2017 May;69(5):1090-1099. doi: 10.1002/art.40045. Epub 2017 Apr 4. Impact factor: 6.918 Publication type: Paper in international publication Authors: Rothwell, Simon, Cooper, Robert G, Lundberg, Ingrid E, Gregersen, Peter K, Hanna, Michael G, Machado, Pedro M, Herbert, Megan K, Pruijn, Ger J M, Lilleker, James B, Roberts, Mark et al. DOI: 10.1002/art.40045
PMID: 28148759 Journal: JOURNAL OF RHEUMATOLOGY Year: 2017 Reference: J Rheumatol. 2017 Feb;44(2):260-261. doi: 10.3899/jrheum.160908. Impact factor: 3.15 Publication type: Letter whit IF Authors: Quesada-Masachs, Estefania, Caballero, Consuelo Modesto et al. DOI: 10.3899/jrheum.160908
PMID: 28131400 Journal: Revista espanola de geriatria y gerontologia Year: 2017 Reference: Rev Esp Geriatr Gerontol. 2017 Jul - Aug;52(4):233-234. doi: 10.1016/j.regg.2016.11.005. Epub 2017 Jan 26. Impact factor: 0 Publication type: Letter or abstract Authors: Agusti, Antonia, Formiga, Francesc, San-Jose, Antonio et al. DOI: 10.1016/j.regg.2016.11.005
PMID: 24630915 Journal: PSYCHIAT RES Year: 2014 Reference: Psychiatry Res. 2014 May 30;216(3):373-8. doi: 10.1016/j.psychres.2014.02.031. Epub 2014 Mar 3. Impact factor: 2.682 Publication type: Paper in international publication Authors: Goma-I-Freixanet, Montserrat, Alegre, Jose, de Sevilla, Tomas Fernandez, Casas, Miquel, Calvo, Natalia, Valero, Sergi, Saez-Francas, Naia et al. DOI: 10.1016/j.psychres.2014.02.031
PMID: 24529880 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 Sep 9;143(5):236. doi: 10.1016/j.medcli.2013.10.028. Epub 2014 Feb 14. Impact factor: 1.252 Publication type: Letter whit IF Authors: Juverdeanu, Roxana-Georgiana, Alegre, Cayetano et al. DOI: 10.1016/j.medcli.2013.10.028
PMID: 24527046 Journal: EVID-BASED COMPL ALT Year: 2014 Reference: Evid Based Complement Alternat Med. 2014;2014:408436. doi: 10.1155/2014/408436. Epub 2014 Jan 9. Impact factor: 2.175 Publication type: Paper in international publication Authors: Sarzi Puttini, Piercarlo C, Alegre, Cayetano, Perrot, Serge, Langhorst, Jost, Hauser, Winfried, Lauche, Romy et al. DOI: 10.1155/2014/408436
PMID: 24469977 Journal: ARTHRIT CARE RES Year: 2014 Reference: Arthritis Care Res (Hoboken). 2014 Jun;66(6):968. doi: 10.1002/acr.22287. Impact factor: 4.039 Publication type: Letter whit IF Authors: Santos-Ortega, Alba, Arcos-Bertiz, Ibai Los, Martinez-Valle, Fernando et al. DOI: 10.1002/acr.22287
PMID: 21641728 Journal: PSYCHONEUROENDOCRINOLOGY Year: 2012 Reference: Psychoneuroendocrinology. 2012 Jan;37(1):65-77. Epub 2011 Jun 8. Impact factor: 5.809 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1016/j.psyneuen.2011.05.005
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.
