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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Team

Fernando Azpiroz Vidaur

Fernando Azpiroz Vidaur

Head of group
Physiology and Pathophysiology of the Digestive Tract
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Monder Abu-Suboh Abadia

Monder Abu-Suboh Abadia

Physiology and Pathophysiology of the Digestive Tract
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Carmen Alonso  Cotoner

Carmen Alonso Cotoner

Physiology and Pathophysiology of the Digestive Tract
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Carolina Malagelada Prats

Carolina Malagelada Prats

Physiology and Pathophysiology of the Digestive Tract
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Fco Javier Santos Vicente

Fco Javier Santos Vicente

Physiology and Pathophysiology of the Digestive Tract
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Luis Gerardo Alcala Gonzalez

Luis Gerardo Alcala Gonzalez

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Fernando Azpiroz Vidaur

Fernando Azpiroz Vidaur

Head of group
Physiology and Pathophysiology of the Digestive Tract
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Monder Abu-Suboh Abadia

Monder Abu-Suboh Abadia

Physiology and Pathophysiology of the Digestive Tract
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Carmen Alonso  Cotoner

Carmen Alonso Cotoner

Physiology and Pathophysiology of the Digestive Tract
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Carolina Malagelada Prats

Carolina Malagelada Prats

Physiology and Pathophysiology of the Digestive Tract
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Fco Javier Santos Vicente

Fco Javier Santos Vicente

Physiology and Pathophysiology of the Digestive Tract
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Luis Gerardo Alcala Gonzalez

Luis Gerardo Alcala Gonzalez

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Research lines

Gut Microbiota

The human microbiome is the collective genomes of all microorganisms living at the multiple sites of the human body (oral cavity, skin, nasal cavity, gastrointestinal tract (GI) and vagina). Human (Homo sapiens) and their commensal microorganisms have evolved together over the last 200,000 years and have become dependent on one another. Interaction between humans and their symbiotic bacteria is essential to many aspects of normal ‘mammalian’ physiology, ranging from metabolic activity to immune homeostasis, and ecological or genetic changes that disturb this mutualism can result in disease. It reflects the evolutionary selection pressures acting at both the levels of the host and the microbial cells and has a direct profound impact on human health. This line of research aims at understanding the role of the gut microbiome in intestinal disorders using ‘omics approaches. Our research group proposes a service-collaboration in Microbiome analysis. You can find further information on our prices at the following URL.

IP: Chaysavanh Manichanh

Hypersensitivity and dysmotility of the gastrointestinal tract

Research has been focused on the origin and mechanisms of the disorders of digestive function. Major advancements have been achieved in relation to the diagnostic  methods to detect neuro-myopathic disorders of the digestive tract. Specifically, an overload test has been developed that increases the sensitivity of intestinal manometry to the detect small bowel motor dysfunction. Non-invasive evaluation of intestinal motility has been approached using an original program of endoluminal image analysis using computer learning techniques and automatic learning methods to videos obtained by means of capsule endoscopy. Furthermore, the possible mechanisms involved in symptoms without apparent cause have been investigated; specifically, the mechanism of abdominal distention has been identified by means of morpho-volumetric analysis of the abdominal; The effects of food and diet on gut function amnd perception in health and disease have been addressed.

IP: Fernando Azpiroz Vidaur

Inflammatory pathways in the gut and therapeutic targets

This research programme includes five projects (supported by Spanish and European public research agencies) aimed at the investigation of the cross-talk and effects of live bacteria of the gut microbiota on the intestinal mucosa. In addition, the programme includes four clinical/physiological studies that address the potential application of new knowledge gained in basic research on inflammatory bowel diseases.

IP: Francisco Guarner Aguilar

Neuro-Immuno-Gastroenterology

The irritable bowel syndrome (IBS), the group of microscopical enteritides, food allergy, gastrointestinal eosinophilopaties, and other functional disorders of the gastrointestinal tract represent more than 50% of digestive consultations. Clinical course is chronic and recurrent. However, sensitive and specific diagnostic biological markers are lacking and clinical management is suboptimal as well. Interestingly, a common finding in the intestine of these patients is the presence of barrier dysfunction, mucosal inflammation and immune activation. Moreover, this finding may be related to the onset and severity of some major clinical symptoms, particularly in IBS. Therefore, our group pursues the detailed comprehension (genetic/gender, immunological, metabolic, cellular and molecular basis) of the mechanisms connecting environmental determinants (stress and infections) to the development of intestinal mucosal microscopical inflammation, with special focus in IBS. Our approach includes experimental studies in animal models and humans as well, yet remains inherently translational in search for better targets helpful for the diagnosis, prevention and treatment of IBS and related disorders. In addition, preclinical and clinical assays are also being carried out.

IP: Fco Javier Santos Vicente

Projects

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IP: Danila Guagnozzi
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01443_INT_GUAGNOZZI
Duration: 11/01/2019 - 30/06/2022

-

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01902_INT_SANTOS
Duration: 11/01/2019 - 30/06/2022

Disfunción neuroepitelial intestinal en la fisiopatología del síndrome del intestino irritable.

IP: Maria Vicario Perez
Collaborators: Merce Albert Bayo
Funding agency: Instituto de Salud Carlos III
Funding: 82400
Reference: FI20/00256
Duration: 01/02/2021 - 31/01/2025

Interacción neuro-epitelial inducida por el exposoma intestinal y su contribución a la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica

IP: Maria Vicario Perez
Collaborators: Merce Albert Bayo, Judit Álvarez González
Funding agency: Instituto de Salud Carlos III
Funding: 20700
Reference: MV21/00097
Duration: 17/01/2022 - 15/07/2022

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IP: Danila Guagnozzi
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01443_INT_GUAGNOZZI
Duration: 11/01/2019 - 30/06/2022

-

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01902_INT_SANTOS
Duration: 11/01/2019 - 30/06/2022

Disfunción neuroepitelial intestinal en la fisiopatología del síndrome del intestino irritable.

IP: Maria Vicario Perez
Collaborators: Merce Albert Bayo
Funding agency: Instituto de Salud Carlos III
Funding: 82400
Reference: FI20/00256
Duration: 01/02/2021 - 31/01/2025

Identificación de un panel integrado de biomarcadores no invasivos predictivos del diagnóstico de colitis microscópica

IP: Danila Guagnozzi
Collaborators: Beatriz Lobo Alvarez, Ana Maria Gonzalez Castro, Lara Aguilera Castro, Marc Pigrau Pastor, Stefania Landolfi
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI17/01443
Duration: 01/01/2018 - 30/06/2022

Sol·licitud beques predoctorals. Modalitat VHIR-AGAUR

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-16-34/PARDO
Duration: 01/03/2017 - 29/02/2020

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IP: Danila Guagnozzi
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01443_INT_GUAGNOZZI
Duration: 11/01/2019 - 30/06/2022

-

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01902_INT_SANTOS
Duration: 11/01/2019 - 30/06/2022

Identificación de perfiles bacterianos y epigenéticos género-dependientes en la fisiopatogenia del síndrome de intestino irritable.

IP: Carmen Alonso Cotoner
Collaborators: Ana Maria Gonzalez Castro, Adoración Nieto Ruiz
Funding agency: Instituto de Salud Carlos III
Funding: 128865
Reference: PI15/00301
Duration: 01/01/2016 - 30/11/2020

Candidatura Juan de la Cierva-incorporación

IP: Fco Javier Santos Vicente
Collaborators: Cristina Martínez Martínez
Funding agency: Ministerio Economía, Industria y Competitividad
Funding: 64000
Reference: IJCI-2015-26099
Duration: 09/01/2017 - 08/01/2019

Sol·licitud beques predoctorals. Modalitat VHIR-AGAUR

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-16-34/PARDO
Duration: 01/03/2017 - 29/02/2020

-

IP: Danila Guagnozzi
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01443_INT_GUAGNOZZI
Duration: 11/01/2019 - 30/06/2022

-

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: PI17/01902_INT_SANTOS
Duration: 11/01/2019 - 30/06/2022

Candidatura Juan de la Cierva-incorporación

IP: Fco Javier Santos Vicente
Collaborators: Cristina Martínez Martínez
Funding agency: Ministerio Economía, Industria y Competitividad
Funding: 64000
Reference: IJCI-2015-26099
Duration: 09/01/2017 - 08/01/2019

Sol·licitud beques predoctorals. Modalitat VHIR-AGAUR

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-16-34/PARDO
Duration: 01/03/2017 - 29/02/2020

Proposta: "Impacto de la homeostasis de poblaciones de virus y bacterias fecales en la fisiopatología del síndrome del intestino irritable"

IP: -
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 17875
Reference: MV17/00043
Duration: 01/01/2018 - 02/10/2018

Desarrollo de un panel diagnóstico innovador para el Síndrome del Intestino Irritable basado en la expresión sistémica diferencial de miRNAs, asociado a manifestaciones clínicas y a patología intestinal

IP: Fco Javier Santos Vicente
Collaborators: Ana Maria Gonzalez Castro, Cristina Martínez Martínez
Funding agency: Instituto de Salud Carlos III
Funding: 171215
Reference: PI14/00994
Duration: 01/01/2015 - 30/04/2018

Candidatura Juan de la Cierva-incorporación

IP: Fco Javier Santos Vicente
Collaborators: Cristina Martínez Martínez
Funding agency: Ministerio Economía, Industria y Competitividad
Funding: 64000
Reference: IJCI-2015-26099
Duration: 09/01/2017 - 08/01/2019

Sol·licitud beques predoctorals. Modalitat VHIR-AGAUR

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-16-34/PARDO
Duration: 01/03/2017 - 29/02/2020

Estudio de las propiedades antiinflamatorias de las bacterias intestinales deficitarias en la enfermedad inflamatoria intestinal

IP: María Antolín Mate
Collaborators: Natalia Borruel Sainz, Francesc Casellas Jordá, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 110715
Reference: PI12/00263
Duration: 01/01/2013 - 30/06/2017

Mecanismos neuroinmunológicos de activación de la respuesta humoral en la fisiopatología del Síndrome del Intestino Irritable: base orgánica de la disfunción intestinal

IP: Maria Vicario Perez
Collaborators: Beatriz Lobo Alvarez, Inés de Torres Ramirez, Ana Maria Gonzalez Castro
Funding agency: Instituto de Salud Carlos III
Funding: 80465
Reference: PI13/00935
Duration: 01/01/2014 - 31/03/2017

Mecanismos neuroinmunológicos subyacentes al desarrollo del Sindrome del Intestino Irritable y su asociación con el género femenino

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 54000
Reference: FI12/00254
Duration: 06/09/2012 - 05/09/2016

Estudio de las propiedades antiinflamatorias de las bacterias intestinales deficitarias en la enfermedad inflamatoria intestinal

IP: María Antolín Mate
Collaborators: Natalia Borruel Sainz, Francesc Casellas Jordá, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 110715
Reference: PI12/00263
Duration: 01/01/2013 - 30/06/2017

Identificación de biomarcadores moleculares género-dependientes de disfunción primaria de la barrera intestinal: relevancia en la patogenia y en el diagnóstico de las enfermedades funcionales digestivas

IP: Carmen Alonso Cotoner
Collaborators: Beatriz Lobo Alvarez, Marc Pigrau Pastor
Funding agency: Instituto de Salud Carlos III
Funding: 116765
Reference: PI12/00314
Duration: 01/01/2013 - 31/12/2016

Mecanismos neuroinmunológicos de activación de la respuesta humoral en la fisiopatología del Síndrome del Intestino Irritable: base orgánica de la disfunción intestinal

IP: Maria Vicario Perez
Collaborators: Beatriz Lobo Alvarez, Inés de Torres Ramirez, Ana Maria Gonzalez Castro
Funding agency: Instituto de Salud Carlos III
Funding: 80465
Reference: PI13/00935
Duration: 01/01/2014 - 31/03/2017

Mecanismos neuroinmunológicos subyacentes al desarrollo del Sindrome del Intestino Irritable y su asociación con el género femenino

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 54000
Reference: FI12/00254
Duration: 06/09/2012 - 05/09/2016

Detección de RNAs no-codificantes relacionados con factores psicosociales y género como biomarcadores

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 129447.59
Reference: EIC-EMBL-2011-0070
Duration: 09/01/2012 - 08/01/2015

Ministerio de Ciencia

Estudio de las propiedades antiinflamatorias de las bacterias intestinales deficitarias en la enfermedad inflamatoria intestinal

IP: María Antolín Mate
Collaborators: Natalia Borruel Sainz, Francesc Casellas Jordá, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 110715
Reference: PI12/00263
Duration: 01/01/2013 - 30/06/2017

Identificación de biomarcadores moleculares género-dependientes de disfunción primaria de la barrera intestinal: relevancia en la patogenia y en el diagnóstico de las enfermedades funcionales digestivas

IP: Carmen Alonso Cotoner
Collaborators: Beatriz Lobo Alvarez, Marc Pigrau Pastor
Funding agency: Instituto de Salud Carlos III
Funding: 116765
Reference: PI12/00314
Duration: 01/01/2013 - 31/12/2016

Mecanismos neuroinmunológicos subyacentes al desarrollo del Sindrome del Intestino Irritable y su asociación con el género femenino

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 54000
Reference: FI12/00254
Duration: 06/09/2012 - 05/09/2016

Detección de RNAs no-codificantes relacionados con factores psicosociales y género como biomarcadores

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 129447.59
Reference: EIC-EMBL-2011-0070
Duration: 09/01/2012 - 08/01/2015

Ministerio de Ciencia

Intensificació

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 30000
Reference: INT13/00233
Duration: 01/01/2014 - 31/12/2014

Identification of signaling pathways and active biological networks associated with the role of eosinophils in stress-induced mucosal pathobiology and clinical relevance for siarrhea-irritable bowel syndrome

IP: Maria Vicario Perez
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 121500
Reference: CP10/00502
Duration: 01/01/2011 - 30/04/2014

Mecanismos neuroinmunológicos subyacentes al desarrollo del Sindrome del Intestino Irritable y su asociación con el género femenino

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 54000
Reference: FI12/00254
Duration: 06/09/2012 - 05/09/2016

Detección de RNAs no-codificantes relacionados con factores psicosociales y género como biomarcadores

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 129447.59
Reference: EIC-EMBL-2011-0070
Duration: 09/01/2012 - 08/01/2015

Ministerio de Ciencia

Identification of signaling pathways and active biological networks associated with the role of eosinophils in stress-induced mucosal pathobiology and clinical relevance for siarrhea-irritable bowel syndrome

IP: Maria Vicario Perez
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 121500
Reference: CP10/00502
Duration: 01/01/2011 - 30/04/2014

Psychosocial and gender-related non-coding NRAs biomarkers in irritable bowel syndrome

IP: Fco Javier Santos Vicente
Collaborators: Marc Pigrau Pastor, Cristina Martínez Martínez
Funding agency: Instituto de Salud Carlos III
Funding: 200540.56
Reference: PI11/00716
Duration: 01/01/2012 - 31/12/2014

Aparato Digestivo

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez
Funding agency: Instituto de Salud Carlos III
Funding: 109440
Reference: CM08/00229
Duration: 01/02/2009 - 31/01/2012

Mecanismos neuroinmunológicos subyacentes al desarrollo del Sindrome del Intestino Irritable y su asociación con el género femenino

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 54000
Reference: FI12/00254
Duration: 06/09/2012 - 05/09/2016

Detección de RNAs no-codificantes relacionados con factores psicosociales y género como biomarcadores

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 129447.59
Reference: EIC-EMBL-2011-0070
Duration: 09/01/2012 - 08/01/2015

Ministerio de Ciencia

Estrés, microbioma y epigenética en el síndrome del intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 5200
Reference: BA12/00082
Duration: 01/07/2012 - 31/08/2012

Aparato Digestivo

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez
Funding agency: Instituto de Salud Carlos III
Funding: 109440
Reference: CM08/00229
Duration: 01/02/2009 - 31/01/2012

Intensificació

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 30000
Reference: INT10/327
Duration: 01/01/2011 - 31/12/2011

Estada a la Faculty of Health Sciences (Canada)

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding: 5200
Reference: BA11/00051
Duration: 16/07/2011 - 16/09/2011

Efecto de la estabilización prolongada del mastocito intestinal con cromoglicato disódico en la evolución clínica y la microinflamación de la mucosa intestinal en los pacientes con síndrome de intestino irritable tipo diarrea

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez, Beatriz Lobo Alvarez, Mar Guilarte Clavero, Inés de Torres Ramirez, Cristina Martínez Martínez
Funding agency: Instituto de Salud Carlos III
Funding: 168190
Reference: EC07/90148
Duration: 01/11/2007 - 30/12/2011

El mastocito y el eosinófilo: células clave en el desarrollo y la perpetuación de la inflamación mucosa en pacientes con síndrome del intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez
Funding agency: Instituto de Salud Carlos III
Funding: 37454.4
Reference: CD05/00060
Duration: 01/03/2006 - 28/02/2010

Aparato Digestivo

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez
Funding agency: Instituto de Salud Carlos III
Funding: 109440
Reference: CM08/00229
Duration: 01/02/2009 - 31/01/2012

Efecto de la estabilización prolongada del mastocito intestinal con cromoglicato disódico en la evolución clínica y la microinflamación de la mucosa intestinal en los pacientes con síndrome de intestino irritable tipo diarrea

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez, Beatriz Lobo Alvarez, Mar Guilarte Clavero, Inés de Torres Ramirez, Cristina Martínez Martínez
Funding agency: Instituto de Salud Carlos III
Funding: 168190
Reference: EC07/90148
Duration: 01/11/2007 - 30/12/2011

Mecanismos moleculares subyacentes a la respuesta diferencial (género dependiente) de la barrera epitelial al estrés en el yeyuno humano. Papel del mastocito e implicaciones en el intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez, Victòria Cardona Dahl, Carmen Alonso Cotoner, Cristina Martínez Martínez
Funding agency: Instituto de Salud Carlos III
Funding: 246840
Reference: PI080940
Duration: 01/01/2009 - 31/12/2012

El mastocito y el eosinófilo: células clave en el desarrollo y la perpetuación de la inflamación mucosa en pacientes con síndrome del intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez
Funding agency: Instituto de Salud Carlos III
Funding: 37454.4
Reference: CD05/00060
Duration: 01/03/2006 - 28/02/2010

Programa de investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM05/00055
Duration: 01/02/2006 - 06/04/2009

Department of Surgery UMDNJ - New Jersey Medical School, Newark, New Jersey

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM05/00055-EST
Duration: 05/04/2008 - 31/01/2009

Aparato Digestivo

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez
Funding agency: Instituto de Salud Carlos III
Funding: 109440
Reference: CM08/00229
Duration: 01/02/2009 - 31/01/2012

Programa de Investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: Carmen Alonso Cotoner
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM04/00019
Duration: 01/02/2005 - 31/01/2008

El mastocito y el eosinófilo: células clave en el desarrollo y la perpetuación de la inflamación mucosa en pacientes con síndrome del intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez
Funding agency: Instituto de Salud Carlos III
Funding: 37454.4
Reference: CD05/00060
Duration: 01/03/2006 - 28/02/2010

Programa de investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM05/00055
Duration: 01/02/2006 - 06/04/2009

Department of Surgery UMDNJ - New Jersey Medical School, Newark, New Jersey

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM05/00055-EST
Duration: 05/04/2008 - 31/01/2009

Programa de Investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: Carmen Alonso Cotoner
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM04/00019
Duration: 01/02/2005 - 31/01/2008

El mastocito y el eosinófilo: células clave en el desarrollo y la perpetuación de la inflamación mucosa en pacientes con síndrome del intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez
Funding agency: Instituto de Salud Carlos III
Funding: 37454.4
Reference: CD05/00060
Duration: 01/03/2006 - 28/02/2010

Programa de investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM05/00055
Duration: 01/02/2006 - 06/04/2009

Mecanismos fisiopatológicos en los transtornos funcionales intestinales

IP: Jorge Serra Pueyo
Collaborators: Fernando Azpiroz Vidaur, Santiago Aguade Bruix
Funding agency: Instituto de Salud Carlos III
Funding: 64260
Reference: PI051250
Duration: 01/01/2006 - 31/12/2008

Programa de Investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: Carmen Alonso Cotoner
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM04/00019
Duration: 01/02/2005 - 31/01/2008

El mastocito y el eosinófilo: células clave en el desarrollo y la perpetuación de la inflamación mucosa en pacientes con síndrome del intestino irritable

IP: Fco Javier Santos Vicente
Collaborators: Maria Vicario Perez
Funding agency: Instituto de Salud Carlos III
Funding: 37454.4
Reference: CD05/00060
Duration: 01/03/2006 - 28/02/2010

Programa de investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: -
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM05/00055
Duration: 01/02/2006 - 06/04/2009

Mecanismos fisiopatológicos en los transtornos funcionales intestinales

IP: Jorge Serra Pueyo
Collaborators: Fernando Azpiroz Vidaur, Santiago Aguade Bruix
Funding agency: Instituto de Salud Carlos III
Funding: 64260
Reference: PI051250
Duration: 01/01/2006 - 31/12/2008

Programa de Investigación en el Laboratorio de Fisiología Digestiva del IR-HUVH

IP: Fco Javier Santos Vicente
Collaborators: Carmen Alonso Cotoner
Funding agency: Instituto de Salud Carlos III
Funding:
Reference: CM04/00019
Duration: 01/02/2005 - 31/01/2008

Caracterización de los mecanismos inmunológicos y papel de la penetración transepitelial bacteriana en la patogenia del síndrome del intestino irritable.

IP: Fco Javier Santos Vicente
Collaborators: María Antolín Mate, Carmen Alonso Cotoner, Joan Ramón Malagelada Benaprés
Funding agency: Instituto de Salud Carlos III
Funding: 83490
Reference: PI020190
Duration: 06/11/2002 - 06/11/2005

Caracterización de los mecanismos inmunológicos y papel de la penetración transepitelial bacteriana en la patogenia del síndrome del intestino irritable.

IP: Fco Javier Santos Vicente
Collaborators: María Antolín Mate, Carmen Alonso Cotoner, Joan Ramón Malagelada Benaprés
Funding agency: Instituto de Salud Carlos III
Funding: 83490
Reference: PI020190
Duration: 06/11/2002 - 06/11/2005

Caracterización de los mecanismos inmunológicos y papel de la penetración transepitelial bacteriana en la patogenia del síndrome del intestino irritable.

IP: Fco Javier Santos Vicente
Collaborators: María Antolín Mate, Carmen Alonso Cotoner, Joan Ramón Malagelada Benaprés
Funding agency: Instituto de Salud Carlos III
Funding: 83490
Reference: PI020190
Duration: 06/11/2002 - 06/11/2005

Caracterización de los mecanismos inmunológicos y papel de la penetración transepitelial bacteriana en la patogenia del síndrome del intestino irritable.

IP: Fco Javier Santos Vicente
Collaborators: María Antolín Mate, Carmen Alonso Cotoner, Joan Ramón Malagelada Benaprés
Funding agency: Instituto de Salud Carlos III
Funding: 83490
Reference: PI020190
Duration: 06/11/2002 - 06/11/2005

Publications

Prevalence of Gastrointestinal Symptoms in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Results of the Prospective Controlled Multinational GI-COVID-19 Study.

PMID: 34751672
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2022
Reference: Am J Gastroenterol. 2022 Jan 1;117(1):147-157. doi: 10.14309/ajg.0000000000001541.
Impact factor: 10.864
Publication type: Paper in international publication
Authors: Eskazan, Tugce; Cremon, Cesare; Barbaro, Maria Raffaella; Salvi, Daniele; Cacciari, Giulia; Kagramanova, Anna; Bordin, Dmitry; Drug, Vasile; Miftode, Edgidia; Fusaroli, Pietro et al.
DOI: 10.14309/ajg.0000000000001541

Rumination syndrome, critical review.

PMID: 34023479
Journal: Gastroenterologia y Hepatologia
Year: 2022
Reference: Gastroenterol Hepatol. 2022 Feb;45(2):155-163. doi: 10.1016/j.gastrohep.2021.03.013. Epub 2021 May 21.
Impact factor: 2.102
Publication type: Review in national publication
Authors: Alcala-Gonzalez, L G; Serra, X; Barba, E et al.
DOI: 10.1016/j.gastrohep.2021.03.013

EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a large-scale epidemiological study in Europe.

PMID: 35126668
Journal: Therapeutic Advances in Gastroenterology
Year: 2022
Reference: Therap Adv Gastroenterol. 2022 Feb 2;15:17562848221074204. doi: 10.1177/17562848221074204. eCollection 2022.
Impact factor: 4.409
Publication type: Paper in international publication
Authors: Racca, Francesca; Lucendo, Alfredo J; Santander, Cecilio; Savarino, Edoardo; Guagnozzi, Danila; Perez-Martinez, Isabel; Perello, Antonia; Guardiola-Arevalo, Antonio; Barrio, Jesus; Elena Betore-Glaria, Maria et al.
DOI: 10.1177/17562848221074204

Management of bloating.

PMID: 35143108
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Mar;34(3):e14333. doi: 10.1111/nmo.14333. Epub 2022 Feb 10.
Impact factor: 3.598
Publication type: Review in international publication
Authors: Serra, Jordi et al.
DOI: 10.1111/nmo.14333

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis.

PMID: 35099124
Journal: United European Gastroenterology Journal
Year: 2021
Reference: United European Gastroenterol J. 2021 Sep;9(7):883-884. doi: 10.1002/ueg2.12090. Epub 2021 Jul 14.
Impact factor: 4.623
Publication type: Letter or abstract
Authors: Pohl, Daniel, Mulak, A, Serra, J, Enck, P, Tack, J, Accarino, Anna, Barbara, Giovanni, Bor, Serhat, Coffin, Benoit, Corsetti, Maura et al.
DOI: 10.1002/ueg2.12090

A Fermented Milk Product Containing B. lactis CNCM I-2494 Improves the Tolerance of a Plant-Based Diet in Patients with Disorders of Gut-Brain Interactions.

PMID: 34960094
Journal: Nutrients
Year: 2021
Reference: Nutrients. 2021 Dec 18;13(12). pii: nu13124542. doi: 10.3390/nu13124542.
Impact factor: 5.719
Publication type: Paper in international publication
Authors: Neve, Boris Le, Martinez-De la Torre, Adrian, Tap, Julien, Ruiz, Adoracion Nieto, Derrien, Muriel, Cotillard, Aurelie, Faurie, Jean-Michel, Barba, Elizabeth, Mego, Marianela, Dornic, Quentin et al.
DOI: 10.3390/nu13124542

Identification of Lynch Syndrome Carriers among Patients with Small Bowel Adenocarcinoma.

PMID: 34944998
Journal: Cancers
Year: 2021
Reference: Cancers (Basel). 2021 Dec 20;13(24). pii: cancers13246378. doi: 10.3390/cancers13246378.
Impact factor: 6.639
Publication type: Paper in international publication
Authors: Sanchez, Ariadna, Bujanda, Luis, Cuatrecasas, Miriam, Bofill, Alex, Alvarez-Urturi, Cristina, Hernandez, Goretti, Aguilera, Lara, Carballal, Sabela, Llach, Joan, Herrera-Pariente, Cristina et al.
DOI: 10.3390/cancers13246378

Dysbiosis and relapse-related microbiome in inflammatory bowel disease: A shotgun metagenomic approach.

PMID: 34938418
Journal: Computational and Structural Biotechnology Journal
Year: 2021
Reference: Comput Struct Biotechnol J. 2021 Dec 2;19:6481-6489. doi: 10.1016/j.csbj.2021.11.037. eCollection 2021.
Impact factor: 7.271
Publication type: Paper in international publication
Authors: Serrano-Gomez, Gerard, Mayorga, Luis, Oyarzun, Inigo, Roca, Joaquim, Borruel, Natalia, Casellas, Francesc, Varela, Encarna, Pozuelo, Marta, Machiels, Kathleen, Guarner, Francisco et al.
DOI: 10.1016/j.csbj.2021.11.037

WCE polyp detection with triplet based embeddings.

PMID: 33130417
Journal: COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Year: 2020
Reference: Comput Med Imaging Graph. 2020 Dec;86:101794. doi: 10.1016/j.compmedimag.2020.101794. Epub 2020 Oct 3.
Impact factor: 3.75
Publication type: Paper in international publication
Authors: Laiz, Pablo, Vitria, Jordi, Wenzek, Hagen, Malagelada, Carolina, Azpiroz, Fernando, Segui, Santi et al.
DOI: 10.1016/j.compmedimag.2020.101794

Publisher Correction: Unraveling the effects of the gut microbiota composition and function on horse endurance physiology.

PMID: 32968096
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Sep 23;10(1):15880. doi: 10.1038/s41598-020-69895-y.
Impact factor: 3.998
Publication type: Letter or abstract
Authors: Plancade, Sandra, Clark, Allison, Philippe, Catherine, Helbling, Jean-Christophe, Moisan, Marie-Pierre, Esquerre, Diane, Le Moyec, Laurence, Robert, Celine, Barrey, Eric, Mach, Nuria et al.
DOI: 10.1038/s41598-020-69895-y

Correction of Dyssynergic Defecation, but not Fiber Supplementation, Reduces Symptoms of Functional Dyspepsia in Patients With Constipation in a Randomized Trial.

PMID: 31811952
Journal: Clinical Gastroenterology and Hepatology
Year: 2020
Reference: Clin Gastroenterol Hepatol. 2020 Oct;18(11):2463-2470.e1. doi: 10.1016/j.cgh.2019.11.048. Epub 2019 Dec 4.
Impact factor: 8.549
Publication type: Paper in international publication
Authors: Huaman, Jose-Walter, Bendezu, Alvaro, Monrroy, Hugo, Samino, Sara, Accarino, Anna, Saperas, Esteban, Azpiroz, Fernando, Mego, Marianela et al.
DOI: 10.1016/j.cgh.2019.11.048

Responses to the Letter to the Editor by Brusciano et al.

PMID: 32856764
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2020
Reference: Neurogastroenterol Motil. 2020 Sep;32(9):e13981. doi: 10.1111/nmo.13981.
Impact factor: 2.946
Publication type: Letter or abstract
Authors: Whorwell, Peter, Serra, Jordi, Pohl, Daniel, Azpiroz, Fernando, Chiarioni, Giuseppe, Ducrotte, Philippe, Gourcerol, Guillaume, Hungin, Amrit Pali S, Layer, Peter, Mendive, Juan-Manuel et al.
DOI: 10.1111/nmo.13981

Risk stratification and treatment of primary biliary cholangitis.

PMID: 30338693
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2019
Reference: Rev Esp Enferm Dig. 2019 Jan;111(1):63-70. doi: 10.17235/reed.2018.5662/2018.
Impact factor: 1.858
Publication type: Review in international publication
Authors: Martinez, Javier, Aguilera, Lara, Albillos, Agustin et al.
DOI: 10.17235/reed.2018.5662/2018

Healthcare Experience and their Relationship with Demographic, Disease and Healthcare-Related Variables: A Cross-Sectional Survey of Patients with Chronic Diseases Using the IEXPAC Scale.

PMID: 30430456
Journal: Patient-Patient Centered Outcomes Research
Year: 2019
Reference: Patient. 2019 Jun;12(3):307-317. doi: 10.1007/s40271-018-0345-1.
Impact factor: 2.673
Publication type: Paper in international publication
Authors: Orozco-Beltran, Domingo, de Toro, Javier, Galindo, Maria J, Marin-Jimenez, Ignacio, Casellas, Francesc, Fuster-RuizdeApodaca, Maria J, Garcia-Vivar, Maria L, Hormigo-Pozo, Antonio, Guilabert, Mercedes, Sanchez-Vega, Nuria et al.
DOI: 10.1007/s40271-018-0345-1

A single faecal microbiota transplantation modulates the microbiome and improves clinical manifestations in a rat model of colitis.

PMID: 31628021
Journal: EBioMedicine
Year: 2019
Reference: EBioMedicine. 2019 Oct;48:630-641. doi: 10.1016/j.ebiom.2019.10.002. Epub 2019 Oct 15.
Impact factor: 6.68
Publication type: Paper in international publication
Authors: Lleal, Marina, Sarrabayrouse, Guillaume, Willamil, Joseane, Santiago, Alba, Pozuelo, Marta, Manichanh, Chaysavanh et al.
DOI: 10.1016/j.ebiom.2019.10.002

Altered host-gut microbes symbiosis in severely malnourished anorexia nervosa (AN) patients undergoing enteral nutrition: An explicative factor of functional intestinal disorders?

PMID: 30527539
Journal: CLINICAL NUTRITION
Year: 2019
Reference: Clin Nutr. 2019 Oct;38(5):2304-2310. doi: 10.1016/j.clnu.2018.10.004. Epub 2018 Oct 9.
Impact factor: 6.402
Publication type: Paper in international publication
Authors: Levenez, Florence, Cournede, Nicole, Dore, Joel, Melchior, Jean-Claude, Pascal, Victoria, Schoenenberger, Andreu, Manichanh, Chaysavanh, Hanachi, Mouna et al.
DOI: 10.1016/j.clnu.2018.10.004

Comparison between small bowel manometric patterns and full-thickness biopsy histopathology in severe intestinal dysmotility.

PMID: 28941004
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Mar;30(3). doi: 10.1111/nmo.13219. Epub 2017 Sep 22.
Impact factor: 3.617
Publication type: Paper in international publication
Authors: Malagelada, C, Karunaratne, T B, Accarino, A, Cogliandro, R F, Landolfi, S, Gori, A, Boschetti, E, Malagelada, J R, Stanghellini, V, Azpiroz, F et al.
DOI: 10.1111/nmo.13219

[Rumination syndrome: Diagnostic and therapeutic difficulties of a not so uncommon disorder].

PMID: 28460821
Journal: ANALES DE PEDIATRIA
Year: 2018
Reference: An Pediatr (Barc). 2018 Feb;88(2):100-105. doi: 10.1016/j.anpedi.2017.03.011. Epub 2017 Apr 29.
Impact factor: 1.14
Publication type: Paper in national publication
Authors: Segarra Canton, Oscar, Azpiroz Vidaur, Fernando, Gimenez Casado, Aida, Lopez Linan, Maria Jose, Barba Orozco, Elisabeth, Accarino Garaventa, Anna, Alvarez Beltran, Marina et al.
DOI: 10.1016/j.anpedi.2017.03.011

Consensus document on exclusion diets in irritable bowel syndrome (IBS).

PMID: 30525861
Journal: Nutricion Hospitalaria
Year: 2018
Reference: Nutr Hosp. 2018 Dec 3;35(6):1450-1466.
Impact factor: 0.747
Publication type: Paper in international publication
Authors: Casellas, Francesc, Burgos, Rosa, Marcos, Ascension, Santos, Javier, Ciriza-de-Los-Rios, Constanza, Garcia-Manzanares, Alvaro, Polanco, Isabel, Puy-Portillo, Maria, Villarino, Antonio, Lema-Marques, Beatriz et al.
DOI:

Probiotics in irritable bowel syndrome: Where are we?

PMID: 30460770
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Dec;30(12):e13513. doi: 10.1111/nmo.13513.
Impact factor: 3.842
Publication type: Review in national publication
Authors: Barbara, Giovanni, Cremon, Cesare, Azpiroz, Fernando et al.
DOI: 10.1111/nmo.13513

High resolution manometry in patients with idiopathic inflammatory myopathy: Elevated prevalence of esophageal involvement and differences according to autoantibody status and clinical subset.

PMID: 27935079
Journal: MUSCLE & NERVE
Year: 2017
Reference: Muscle Nerve. 2017 Sep;56(3):386-392. doi: 10.1002/mus.25507. Epub 2017 Apr 4.
Impact factor: 2.713
Publication type: Paper in international publication
Authors: Casal-Dominguez, Maria, Pinal-Fernandez, Iago, Mego, Marianela, Accarino, Anna, Jubany, Lluis, Azpiroz, Fernando, Selva-O'Callaghan, Albert et al.
DOI: 10.1002/mus.25507

Effect of Chicory-derived Inulin on Abdominal Sensations and Bowel Motor Function.

PMID: 27680592
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2017
Reference: J Clin Gastroenterol. 2017 Aug;51(7):619-625. doi: 10.1097/MCG.0000000000000723.
Impact factor: 3.163
Publication type: Paper in international publication
Authors: Azpiroz, Fernando, Molne, Laura, Mendez, Sara, Nieto, Adoracion, Manichanh, Chaysavanh, Mego, Marianela, Accarino, Anna, Santos, Javier, Sailer, Manuela, Theis, Stephan et al.
DOI: 10.1097/MCG.0000000000000723

Functional dyspepsia.

PMID: 29099093
Journal: Nature Reviews Disease Primers
Year: 2017
Reference: Nat Rev Dis Primers. 2017 Nov 3;3:17081. doi: 10.1038/nrdp.2017.81.
Impact factor: 6.389
Publication type: Review in international publication
Authors: Azpiroz, Fernando, Enck, Paul, Feinle-Bisset, Christine, Holtmann, Gerald, Lackner, Jeffrey M, Ronkainen, Jukka, Schemann, Michael, Stengel, Andreas, Tack, Jan, Zipfel, Stephan et al.
DOI: 10.1038/nrdp.2017.81

Irritable bowel syndrome diagnosis and management: A simplified algorithm for clinical practice.

PMID: 29026591
Journal: United European Gastroenterology Journal
Year: 2017
Reference: United European Gastroenterol J. 2017 Oct;5(6):773-788. doi: 10.1177/2050640617731968. Epub 2017 Sep 28.
Impact factor: 3.673
Publication type: Review in national publication
Authors: Moayyedi, Paul, Mearin, Fermin, Azpiroz, Fernando, Andresen, Viola, Barbara, Giovanni, Corsetti, Maura, Emmanuel, Anton, Hungin, A Pali S, Layer, Peter, Stanghellini, Vincenzo et al.
DOI: 10.1177/2050640617731968

Mechanism-Oriented Therapy of Irritable Bowel Syndrome.

PMID: 27138605
Journal: ADVANCES IN THERAPY
Year: 2016
Reference: Adv Ther. 2016 Jun;33(6):877-93. doi: 10.1007/s12325-016-0336-3. Epub 2016 Apr 30.
Impact factor: 2.503
Publication type: Review in international publication
Authors: Malagelada, Juan R, Malagelada, Carolina et al.
DOI: 10.1007/s12325-016-0336-3

Gastroduodenal Disorders.

PMID: 27147122
Journal: GASTROENTEROLOGY
Year: 2016
Reference: Gastroenterology. 2016 May;150(6):1380-92. doi: 10.1053/j.gastro.2016.02.011.
Impact factor: 18.187
Publication type: Review in international publication
Authors: Stanghellini, Vincenzo, Chan, Francis K L, Hasler, William L, Malagelada, Juan R, Suzuki, Hidekazu, Tack, Jan, Talley, Nicholas J et al.
DOI: 10.1053/j.gastro.2016.02.011

The joint power of sex and stress to modulate brain-gut-microbiota axis and intestinal barrier homeostasis: implications for irritable bowel syndrome.

PMID: 26556786
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2016
Reference: Neurogastroenterol Motil. 2016 Apr;28(4):463-86. doi: 10.1111/nmo.12717. Epub 2015 Nov 11.
Impact factor: 3.587
Publication type: Paper in international publication
Authors: Santos, J, Pigrau, M, Rodino-Janeiro, B K, Casado-Bedmar, M, Lobo, B, Vicario, M, Alonso-Cotoner, C et al.
DOI: 10.1111/nmo.12717

Galectin-4 interacts with the drug transporter human concentrative nucleoside transporter 3 to regulate its function.

PMID: 26481311
Journal: FASEB JOURNAL
Year: 2016
Reference: FASEB J. 2016 Feb;30(2):544-54. doi: 10.1096/fj.15-272773. Epub 2015 Oct 19.
Impact factor: 5.043
Publication type: Paper in international publication
Authors: Fernandez-Calotti, Paula, Casulleras, Olga, Antolin, Maria, Guarner, Francisco, Pastor-Anglada, Marcal et al.
DOI: 10.1096/fj.15-272773

World gastroenterology organisation global guidelines: dysphagia--global guidelines and cascades update September 2014.

PMID: 25853874
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2015
Reference: J Clin Gastroenterol. 2015 May-Jun;49(5):370-8. doi: 10.1097/MCG.0000000000000307.
Impact factor: 3.498
Publication type: Paper in international publication
Authors: Malfertheiner, Peter, Salis, Graciela, Sharma, Prateek, Sifrim, Daniel, Vakil, Nimish, Le Mair, Anton, Lindberg, Greger, Kahrilas, Peter, Fried, Michael, De Looze, Danny et al.
DOI: 10.1097/MCG.0000000000000307

The gut microbiome: What do we know?

PMID: 31040957
Journal: Clinical liver disease
Year: 2015
Reference: Clin Liver Dis (Hoboken). 2015 May 7;5(4):86-90. doi: 10.1002/cld.454. eCollection 2015 Apr.
Impact factor: 0
Publication type: Review in international publication
Authors: Guarner, Francisco et al.
DOI: 10.1002/cld.454

The intestinal barrier function and its involvement in digestive disease.

PMID: 26541659
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2015
Reference: Rev Esp Enferm Dig. 2015 Nov;107(11):686-96. doi: 10.17235/reed.2015.3846/2015.
Impact factor: 1.414
Publication type: Review in international publication
Authors: Salvo Romero, Eloisa, Alonso Cotoner, Carmen, Pardo Camacho, Cristina, Casado Bedmar, Maite, Vicario, Maria et al.
DOI: 10.17235/reed.2015.3846/2015

Abdomino-Thoracic Mechanisms of Functional Abdominal Distension And Correction by Biofeedback.

PMID: 25500424
Journal: GASTROENTEROLOGY
Year: 2015
Reference: Gastroenterology. 2015 Apr;148(4):732-9. doi: 10.1053/j.gastro.2014.12.006. Epub 2014 Dec 11.
Impact factor: 13.926
Publication type: Paper in international publication
Authors: Barba, Elizabeth, Burri, Emanuel, Accarino, Anna, Cisternas, Daniel, Quiroga, Sergi, Monclus, Eva, Navazo, Isabel, Malagelada, Juan-R, Azpiroz, Fernando et al.
DOI: 10.1053/j.gastro.2014.12.006

Detection of wrinkle frames in endoluminal videos using betweenness centrality measures for images.

PMID: 25375680
Journal: IEEE J BIOMED HEALTH
Year: 2014
Reference: IEEE J Biomed Health Inform. 2014 Nov;18(6):1831-8. doi: 10.1109/JBHI.2014.2304179.
Impact factor: 0
Publication type: Paper in international publication
Authors: Segui, Santi, Drozdzal, Michal, Zaytseva, Ekaterina, Malagelada, Carolina, Azpiroz, Fernando, Radeva, Petia, Vitria, Jordi et al.
DOI: 10.1109/JBHI.2014.2304179

Perception of lactose intolerance in irritable bowel syndrome patients.

PMID: 25089542
Journal: EUR J GASTROEN HEPAT
Year: 2014
Reference: Eur J Gastroenterol Hepatol. 2014 Oct;26(10):1167-75. doi: 10.1097/MEG.0000000000000089.
Impact factor: 2.152
Publication type: Paper in international publication
Authors: Dainese, Raffaella, Casellas, Francesc, Marine-Barjoan, Eugenia, Vivinus-Nebot, Mylene, Schneider, Stephane M, Hebuterne, Xavier, Piche, Thierry et al.
DOI: 10.1097/MEG.0000000000000089

Autoimmune pancreatitis type-1 associated with intraduct papillary mucinous neoplasm: report of two cases.

PMID: 25062884
Journal: PANCREATOLOGY
Year: 2014
Reference: Pancreatology. 2014 Jul-Aug;14(4):316-8. doi: 10.1016/j.pan.2014.04.032. Epub 2014 May 9.
Impact factor: 2.504
Publication type: Letter or abstract
Authors: Vaquero, Eva C, Salcedo, Maria T, Cuatrecasas, Miriam, De Leon, Hannah, Merino, Xavier, Navarro, Salvador, Gines, Angels, Abu-Suboh, Monder, Balsells, Joaquim, Fernandez-Cruz, Laureano et al.
DOI: 10.1016/j.pan.2014.04.032

Intestinal barrier function and the brain-gut axis.

PMID: 24997030
Journal: ADV EXP MED BIOL
Year: 2014
Reference: Adv Exp Med Biol. 2014;817:73-113. doi: 10.1007/978-1-4939-0897-4_4.
Impact factor: 2.012
Publication type: Review in national publication
Authors: Alonso, Carmen, Vicario, Maria, Pigrau, Marc, Lobo, Beatriz, Santos, Javier et al.
DOI: 10.1007/978-1-4939-0897-4_4

[Recommendations of the Spanish Pancreatic Club on the diagnosis and treatment of chronic pancreatitis: part 1 (diagnosis)].

PMID: 23566414
Journal: Gastroenterologia y Hepatologia
Year: 2013
Reference: Gastroenterol Hepatol. 2013 May;36(5):326-39. doi: 10.1016/j.gastrohep.2012.12.004. Epub 2013 Apr 6.
Impact factor: 0.567
Publication type: Paper in national publication
Authors: Gomez, Luis, Iglesias-Garcia, Julio, Garcia-Malpartida, Katherine, Guarner, Luisa, Larino-Noia, Jose, Lluis, Felix, Lopez, Antonio, Molero, Xavier, Moreno-Perez, Oscar, Navarro, Salvador et al.
DOI: 10.1016/j.gastrohep.2012.12.004

Acute pancreatitis and superior mesenteric artery syndrome.

PMID: 24641461
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2013
Reference: Rev Esp Enferm Dig. 2013 Nov-Dec;105(10):626-8. doi: 10.4321/s1130-01082013001000009.
Impact factor: 1.652
Publication type: Review in international publication
Authors: Sihuay-Diburga, Denisse Joan, Accarino-Garaventa, Anna, Vilaseca-Montplet, Jaime, Azpiroz-Vidaur, Fernando et al.
DOI: 10.4321/s1130-01082013001000009

Hot topics in gut microbiota.

PMID: 24917977
Journal: United European gastroenterology journal
Year: 2013
Reference: United European Gastroenterol J. 2013 Oct;1(5):311-8. doi: 10.1177/2050640613502477.
Impact factor: 0
Publication type: Review in international publication
Authors: Dore, Joel, Simren, Magnus, Buttle, Lisa, Guarner, Francisco et al.
DOI: 10.1177/2050640613502477

Colonic necrosis due to calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.

PMID: 23859454
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2013
Reference: Rev Esp Enferm Dig. 2013 Apr;105(4):232-4. doi: 10.4321/s1130-01082013000400010.
Impact factor: 1.652
Publication type: Paper in international publication
Authors: Castillo-Cejas, Maria Dolores, de-Torres-Ramirez, Ines, Alonso-Cotoner, Carmen et al.
DOI: 10.4321/s1130-01082013000400010

Effect upon hospital activity of the application of a continued care model centered on patients with inflammatory bowel disease.

PMID: 22300112
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2012
Reference: Rev Esp Enferm Dig. 2012 Feb;104(1):16-20. doi: 10.4321/s1130-01082012000100004.
Impact factor: 1.548
Publication type: Paper in national publication
Authors: Castells, Isabel, Borruel-Sainz, Natalia, Casellas-Jorda, Francesc, Torrejon-Herrera, Antonio et al.
DOI: 10.4321/s1130-01082012000100004

Categorization and segmentation of intestinal content frames for wireless capsule endoscopy.

PMID: 24218705
Journal: IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE
Year: 2012
Reference: IEEE Trans Inf Technol Biomed. 2012 Nov;16(6):1341-52.
Impact factor: 1.676
Publication type: Paper in international publication
Authors: Segui, Santi, Drozdzal, Michal, Vilarino, Fernando, Malagelada, Carolina, Azpiroz, Fernando, Radeva, Petia, Vitria, Jordi et al.
DOI: 10.1109/TITB.2012.2221472

Effect of a mixture of inulin and fructo-oligosaccharide on Lactobacillus and Bifidobacterium intestinal microbiota of patients receiving radiotherapy: a randomised, double-blind, placebo-controlled trial.

PMID: 23588438
Journal: Nutricion Hospitalaria
Year: 2012
Reference: Nutr Hosp. 2012 Nov-Dec;27(6):1908-15. doi: 10.3305/nh.2012.27.6.5992.
Impact factor: 1.12
Publication type: Paper in international publication
Authors: Lozano, M A, Moreno, Y, Paron, L, de la Cuerda, C, Breton, I, Camblor, M, Garcia-Hernandez, J, Guarner, F, Hernandez, M, Velasco, C et al.
DOI: 10.3305/nh.2012.27.6.5992

Ustekinumab induction and maintenance therapy in refractory Crohn's disease.

PMID: 23075178
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2012
Reference: N Engl J Med. 2012 Oct 18;367(16):1519-28. doi: 10.1056/NEJMoa1203572.
Impact factor: 53.298
Publication type: Paper in international publication
Authors: Fishman, S, Sandborn, William J, Gasink, Christopher, Gao, Long-Long, Blank, Marion A, Johanns, Jewel, Guzzo, Cynthia, Sands, Bruce E, Hanauer, Stephen B, Targan, Stephan et al.
DOI: 10.1056/NEJMoa1203572

[Information for patients. Functional abdominal pain].

PMID: 21951120
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2011
Reference: Rev Esp Enferm Dig. 2011 Sep;103(9):492. doi: 10.4321/s1130-01082011000900010.
Impact factor: 1.13
Publication type: Letter or abstract
Authors: Accarino, Anna et al.
DOI: 10.4321/s1130-01082011000900010

Postoperative pain after haemorrhoidectomy: role of impaired evacuation.

PMID: 20402734
Journal: Colorectal Disease
Year: 2011
Reference: Colorectal Dis. 2011 Aug;13(8):926-9. doi: 10.1111/j.1463-1318.2010.02280.x. Epub 2010 Apr 5.
Impact factor: 2.41
Publication type: Paper in international publication
Authors: , , et al.
DOI: 10.1111/j.1463-1318.2010.02280.x

Guidelines for the design, conduct and reporting of human intervention studies to evaluate the health benefits of foods.

PMID: 22129662
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2011
Reference: Br J Nutr. 2011 Nov;106 Suppl 2:S3-15.
Impact factor: 3.072
Publication type: Paper in international publication
Authors: Berta, Jean-Louis, Bub, Achim, de Vries, Jan, Guarner, Francisco, Hasselwander, Oliver, Hendriks, Henk, Jakel, Martin, Koletzko, Berthold V, Patterson, Chris C, Richelle, Myriam et al.
DOI: 10.1017/S0007114511003606

A New Validation of the Spanish Work Productivity and Activity Impairment Questionnaire-Crohn's Disease Version.

PMID: 21914506
Journal: VALUE IN HEALTH
Year: 2011
Reference: Value Health. 2011 Sep-Oct;14(6):859-61. Epub 2011 May 28.
Impact factor: 2.342
Publication type: Paper in international publication
Authors: Calvet, Xavier, Gallardo, Olga, Vergara, Mercedes, Montserrat, Antonia, Casellas, Francesc, Villoria, Albert, Suarez, David, Maudsley, Michael, Ricart, Elena et al.
DOI: 10.1016/j.jval.2011.02.1179

[Gastroparesis].

PMID: 20524764
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2010
Reference: Rev Esp Enferm Dig. 2010 May;102(5):337. doi: 10.4321/s1130-01082010000500010.
Impact factor: 0.994
Publication type: Letter or abstract
Authors: Accarino, A et al.
DOI: 10.4321/s1130-01082010000500010

Fatigue as a determinant of health in patients with celiac disease.

PMID: 19935081
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2010
Reference: J Clin Gastroenterol. 2010 Jul;44(6):423-7. doi: 10.1097/MCG.0b013e3181c41d12.
Impact factor: 2.207
Publication type: Paper in international publication
Authors: Jorda, Francesc Casellas, Lopez Vivancos, Josefa et al.
DOI: 10.1097/MCG.0b013e3181c41d12

Current level of consensus on probiotic science--report of an expert meeting--London, 23 November 2009.

PMID: 21637035
Journal: Gut microbes
Year: 2010
Reference: Gut Microbes. 2010 Nov-Dec;1(6):436-9. doi: 10.4161/gmic.1.6.13610.
Impact factor: 2.19
Publication type: Paper in international publication
Authors: Rowland, Ian, Capurso, Lucio, Collins, Kevin, Cummings, John, Delzenne, Nathalie, Goulet, Olivier, Guarner, Francisco, Marteau, Philippe, Meier, Remy et al.
DOI: 10.4161/gmic.1.6.13610

Consensus statements from the Workshop "Probiotics and Health: Scientific Evidence"

PMID: 21336423
Journal: Nutricion Hospitalaria
Year: 2010
Reference: Nutr Hosp. 2010 Oct;25(5):700-704.
Impact factor: 1.065
Publication type: Paper in national publication
Authors: , , et al.
DOI:

The challenge of developing new therapies for irritable bowel syndrome.

PMID: 21180543
Journal: Therapeutic advances in gastroenterology
Year: 2009
Reference: Therap Adv Gastroenterol. 2009 Jul;2(4):201-3. doi: 10.1177/1756283X09335638.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Whorwell, Peter J, Azpiroz, Fernando et al.
DOI: 10.1177/1756283X09335638

Predictive factors of poor response to intravenous cyclosporine in steroid-refractory ulcerative colitis.

PMID: 19388796
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2009
Reference: Rev Esp Enferm Dig. 2009 Mar;101(3):163-71. doi: 10.4321/s1130-01082009000300002.
Impact factor: 1.263
Publication type: Paper in national publication
Authors: Huaman Rios, J W, Casellas Jorda, F, Malagelada Benapres, J R et al.
DOI: 10.4321/s1130-01082009000300002

[Application of a model of continued attention in inflammatory bowel disease: the Crohn-colitis care unit].

PMID: 19231678
Journal: Gastroenterol Hepatol
Year: 2009
Reference: Gastroenterol Hepatol. 2009 Feb;32(2):77-82. doi: 10.1016/j.gastrohep.2008.09.015. Epub 2009 Feb 5.
Impact factor: 0
Publication type: Paper in national publication
Authors: Casellas Jorda, Francesc, Malagelada Benapres, Juan Ramon, Castillejo Badia, Neus, Borruel Sainz, Natalia, Torrejon Herrera, Antonio, Masachs Peracaula, Miquel, Castells Carner, Isabel et al.
DOI: 10.1016/j.gastrohep.2008.09.015

Validation of the Spanish Work Productivity and Activity impairment questionnaire: Crohn's disease version.

PMID: 19404204
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2009
Reference: Eur J Gastroenterol Hepatol. 2009 Jul;21(7):809-15.
Impact factor: 2.08
Publication type: Paper in international publication
Authors: Vergara, Mercedes, Montserrat, Antonia, Casellas, Francesc, Maudsley, Michael, Gallardo, Olga, Ricart, Elena, Calvet, Xavier et al.
DOI: 10.1097/MEG.0b013e32830f4c9e

Neuropharmacology of stress-induced mucosal inflammation: implications for inflammatory bowel disease and irritable bowel syndrome.

PMID: 18537634
Journal: CURRENT MOLECULAR MEDICINE
Year: 2008
Reference: Curr Mol Med. 2008 Jun;8(4):258-73. doi: 10.2174/156652408784533788.
Impact factor: 4.624
Publication type: Editorail in international publication
Authors: Santos, Javier, Alonso, Carmen, Vicario, Maria, Ramos, Laura, Lobo, Beatriz, Malagelada, J-Ramon et al.
DOI: 10.2174/156652408784533788

Stress neuropeptides evoke epithelial responses via mast cell activation in the rat colon.

PMID: 18691825
Journal: PSYCHONEUROENDOCRINOLOGY
Year: 2008
Reference: Psychoneuroendocrinology. 2008 Oct;33(9):1248-56. doi: 10.1016/j.psyneuen.2008.07.002. Epub 2008 Aug 8.
Impact factor: 4.422
Publication type: Paper in international publication
Authors: Vicario, Maria, Alonso, Carmen, Perdue, Mary H, Guilarte, Mar, Yates, Derrick, Santos, Javier et al.
DOI: 10.1016/j.psyneuen.2008.07.002

Maladaptive intestinal epithelial responses to life stress may predispose healthy women to gut mucosal inflammation.

PMID: 18455999
Journal: GASTROENTEROLOGY
Year: 2008
Reference: Gastroenterology. 2008 Jul;135(1):163-172.e1. doi: 10.1053/j.gastro.2008.03.036. Epub 2008 Mar 22.
Impact factor: 11.673
Publication type: Paper in international publication
Authors: Alonso, Carmen, Guilarte, Mar, Vicario, Maria, Ramos, Laura, Ramadan, Ziad, Antolin, Maria, Martinez, Cristina, Rezzi, Serge, Saperas, Esteban, Kochhar, Sunil et al.
DOI: 10.1053/j.gastro.2008.03.036

Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum.

PMID: 17005763
Journal: GUT
Year: 2007
Reference: Gut. 2007 Feb;56(2):203-9. doi: 10.1136/gut.2006.100594. Epub 2006 Sep 27.
Impact factor: 9.002
Publication type: Paper in international publication
Authors: Guilarte, Mar, Santos, Javier, de Torres, Ines, Alonso, Carmen, Vicario, Maria, Ramos, Laura, Martinez, Cristina, Casellas, Francesc, Saperas, Esteban, Malagelada, Juan Ramon et al.
DOI: 10.1136/gut.2006.100594

Targeting mast cells in the treatment of functional gastrointestinal disorders.

PMID: 16956793
Journal: CURRENT OPINION IN PHARMACOLOGY
Year: 2006
Reference: Curr Opin Pharmacol. 2006 Dec;6(6):541-6. doi: 10.1016/j.coph.2006.08.001. Epub 2006 Sep 7.
Impact factor: 5.366
Publication type: Editorail in international publication
Authors: Alonso, Carmen, Malagelada, Juan Ramon, Vicario, Maria, Guilarte, Mar, Santos, Javier et al.
DOI: 10.1016/j.coph.2006.08.001

Anisakis simplex-induced small bowel obstruction after fish ingestion: preliminary evidence for response to parenteral corticosteroids.

PMID: 16206499
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Ga
Year: 2005
Reference: Clin Gastroenterol Hepatol. 2005 Jul;3(7):667-71. doi: 10.1016/s1542-3565(05)00363-0.
Impact factor: 0
Publication type: Paper in international publication
Authors: Malagelada, Juan Ramon, Santos, Javier, Guilarte, Mar, Alonso, Carmen, Ramos, Laura, Vilaseca, Jaime et al.
DOI: 10.1016/s1542-3565(05)00363-0

Pathogenesis of irritable bowel syndrome: the mast cell connection.

PMID: 15764142
Journal: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Year: 2005
Reference: Scand J Gastroenterol. 2005 Feb;40(2):129-40. doi: 10.1080/00365520410009410.
Impact factor: 1.824
Publication type: Editorail in international publication
Authors: Malagelada, J R, Alonso, Carmen, Guilarte, Mar, Santos, Javier et al.
DOI: 10.1080/00365520410009410

Thesis

Design and validation of a short food frequency questionnaire to relate diet with the gut microbiota

PhD student: Francisca Yañez Araya
Director/s: Chaysavanh Manichanh
University: Universitat Autònoma de Barcelona
Year: 2022

Estudi observacional en colitis ulcerosa per investigar la composició de la microbiotica intestinal en pacients en remisió de llarga durada

PhD student: Claudia Maria Herrera de Guise
Director/s: Francisco Guarner Aguilar
University: Universitat Autònoma de Barcelona
Year: 2021

Functional profiling of the human gut microbiome using metatranscriptomic approach

PhD student: Xavier Martínez Serrano
Director/s: Chaysavanh Manichanh
University: Universitat Autònoma de Barcelona
Year: 2020

Mecanismos citotóxicos y humorales implicados en la etiopatogénesis de la esofagitis eosinofílica

PhD student: Marina Fortea Guillamon
Director/s: Fernando Azpiroz Vidaur, Maria Vicario Perez
University: Universitat Autònoma de Barcelona
Year: 2020

Relación entre dieta, función y síntomas digestivos

PhD student: José Wálter Huamán Ríos
Director/s: Ana María Accarino Garaventa, Fernando Azpiroz Vidaur
University: Universitat Autònoma de Barcelona
Year: 2020

La respuesta humoral y las interacciones neuro-inmunológicas en la mucosa intestinal como contribuyentes en la patofisiología del Síndrome del Intestino Irritable con predominio de diarrea

PhD student: Cristina Pardo Camacho
Director/s: Maria Vicario Perez, Fco Javier Santos Vicente
University: Universitat Autònoma de Barcelona
Year: 2020

Metagenómica en la enfermedad inflamatoria intestinal

PhD student: Marta Pozuelo Del Rio
Director/s: Chaysavanh Manichanh
University: Universitat Autònoma de Barcelona
Year: 2019

Implicación del eosinófilo intestinal y producción de factor liberador de corticotropina en la fisiopatología del Síndrome del Intestino Irritable con predominio de diarrea

PhD student: Eloisa Salvo Romero
Director/s: Maria Vicario Perez, Fco Javier Santos Vicente
University: Universitat Autònoma de Barcelona
Year: 2018

Estudio de las alteraciones del microbioma intestinal y extra-intestinal en ratas y humanos durante la progresión de la cirrosis

PhD student: Alba Santiago Badenas
Director/s: Chaysavanh Manichanh
University: Universitat Autònoma de Barcelona
Year: 2018

Molecular Mechanisms and effect of acute and psychosocial stress on the intestinal barrier function. Implications on the iritable bowel syndrome

PhD student: Marc Pigrau Pastor
Director/s: Fco Javier Santos Vicente, Maria Vicario Perez, Carmen Alonso Cotoner
University: Universitat Autònoma de Barcelona
Year: 2018

Mecanismo de producción de los síntomas digestivos funcionales

PhD student: Rogger Alvaro Bendezú García
Director/s: Fernando Azpiroz Vidaur
University: Universitat Autònoma de Barcelona
Year: 2016

Fisiología, fisiopatología y tratamiento de la Distensión abdominal

PhD student: Elizabeth Barba Orozco
Director/s: Elizabeth Barba Orozco, Ana María Accarino Garaventa, Fernando Azpiroz Vidaur
University: Universitat Autònoma de Barcelona
Year: 2015

Fisiología y Fisiopatología de la distensión abdominal: Gas intestinal

PhD student: Marianela Mego Silva
Director/s: Fernando Azpiroz Vidaur
University: Universitat Autònoma de Barcelona
Year: 2015

Efecto de la administración oral del agente estabilizador del mastocito, cromoglicato disódico, sobre la evolución clínica y biológica en pacientes con síndrome del intestino irritable con predominio de diarrea.

PhD student: Beatriz Lobo Alvarez
Director/s: Fco Javier Santos Vicente, Maria Vicario Perez
University: Universitat Autònoma de Barcelona
Year: 2013

Evaluación de la motilidad intestinal mediante análisis de imágenes endoluminales.

PhD student: Carolina Malagelada Prats
Director/s: Fernando Azpiroz Vidaur
University: Universitat Autònoma de Barcelona
Year: 2010

Disfunción e inflamación de la mucosa intestinal inducida por el estrés psicosocial crónico y su relevancia translacional para el síndrome del intestino irritable.

PhD student: Carmen Alonso Cotoner
Director/s: Joan Ramón Malagelada Benaprés, Fco Javier Santos Vicente
University: Universitat Autònoma de Barcelona
Year: 2010

Interacciones de las bacterias de la flora con el sistema inmune intestinal

PhD student: Natalia Borruel Sainz
Director/s:
University: Universitat Autònoma de Barcelona
Year: 2005

Blog

News

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

Onze investigadors i investigadores de Vall d’Hebron faran xerrades i tallers amb l’objectiu d’apropar la ciència a tothom.

His project reports the increased diagnostic power of high-resolution bowel manometry in patients with suspected small bowel motor disorder compared to conventional technology.

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Physiology and Physiopathology of the digestive tract.
Start date:
21/11/2022
End date:
05/12/2022
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Research Nurse - Physiology and Physiopathology of the digestive tract
Start date:
09/11/2022
End date:
23/11/2022
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Assistant in Biomedical Research in IBD -Digestive System Research Unit.
Start date:
20/10/2022
End date:
03/11/2022
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